CIDeRplusGeneral Information:
| Id: | 989 (click here to show other Interactions for entry) |
| Diseases: |
Parkinson disease
|
| Homo sapiens | |
| BTO:0000793 SH-SY5Y cell | |
| article | |
| Reference: | Niso-Santano M et al.(2010) Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis Free Radic. Biol. Med. 48: 1370-1381 [PMID: 20202476] |
Interaction Information:
| Comment | Paraquat is a well known complex I inhibitor releasing reactive oxygen species (ROS) and dopaminergic toxicants. It is widely used to model PD. |
|
Formal Description Interaction-ID: 6145 |
drug/chemical compound increases_quantity of drug/chemical compound Reactive oxygen species |