General Information:

Id: 9,836 (click here to show other Interactions for entry)
Diseases: Cardiomyopathy, dilated
Mammalia
article
Reference: Rafiq K et al.(2014) c-Cbl inhibition improves cardiac function and survival in response to myocardial ischemia Circulation 129: 2031-2043 [PMID: 24583314]

Interaction Information:

Comment Myocytes challenged with hypertrophic agonists norepinephrine (primarily an alpha-adrenergic receptor agonist), isoproterenol (a non-selective alpha-adrenergic receptor agonist), thrombin, or TNF-alpha for 48 hours showed an increase in c-Cbl accumulation compared to controls in neonatal rat cardiomyocytes.
Formal Description
Interaction-ID: 103638

drug/chemical compound

Noradrenaline

increases_quantity of

gene/protein

CBL

in cardiomyocytes; of neonatal rats