General Information:
Id: | 9,836 (click here to show other Interactions for entry) |
Diseases: |
Cardiomyopathy, dilated
|
Mammalia | |
article | |
Reference: | Rafiq K et al.(2014) c-Cbl inhibition improves cardiac function and survival in response to myocardial ischemia Circulation 129: 2031-2043 [PMID: 24583314] |
Interaction Information:
Comment | Myocytes challenged with hypertrophic agonists norepinephrine (primarily an alpha-adrenergic receptor agonist), isoproterenol (a non-selective alpha-adrenergic receptor agonist), thrombin, or TNF-alpha for 48 hours showed an increase in c-Cbl accumulation compared to controls in neonatal rat cardiomyocytes. |
Formal Description Interaction-ID: 103638 |
drug/chemical compound increases_quantity of gene/protein |