General Information:

Id: 9,689 (click here to show other Interactions for entry)
Diseases: Anxiety disorders
Major depressive disorder - [OMIM]
Metabolic
Mammalia
review
Reference: Higuchi Y et al.(2017) Regulatory Pathways of Monoamine Oxidase A during Social Stress Front Neurosci 11: 604 [PMID: 29163009]

Interaction Information:

Comment FOXO1 is involved in the valproate-induced activation of MAO-A gene expression, catalytic activity, and promoter activity. FOXO1 represses the transcription of MAO-A by directly binding to a FOXO1-binding site of the MAO-A promoter.
Formal Description
Interaction-ID: 102250

drug/chemical compound

Valproic acid

increases_activity of

gene/protein

MAOA

Drugbank entries Show/Hide entries for Valproic acid or MAOA