General Information:

Id: 9,274 (click here to show other Interactions for entry)
Diseases: Gastrointestinal
Major depressive disorder - [OMIM]
Metabolic
Neurological
Mammalia
review
Reference: Evrensel A and Ceylan ME(2015) The Gut-Brain Axis: The Missing Link in Depression Clin Psychopharmacol Neurosci 13: 239-244 [PMID: 26598580]

Interaction Information:

Comment The human gut microbiota contains more than 1,000 species and over 7,000 subspecies. Gut bacteria are able to produce active metabolites for human organ systems. For example; Lactobacillus and Bifidobacterium synthesize gamma-aminobutyric acid (GABA) from monosodium glutamate. Escherichia coli, Bacillus and Saccharomyces produce norepinefrin; Candida, Streptococcus, Escherichia and Enterococcus produce serotonin, and Bacillus and Serratia produce dopamine.
Formal Description
Interaction-ID: 98820

environment

Lactobacillus

increases_quantity of

drug/chemical compound

GABA

from monosodium glutamate