General Information:

Id: 9,140 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Gastrointestinal
Metabolic
Neurological
Mammalia
review
Reference: Giau VV et al.Gut Microbiota and Their Neuroinflammatory Implications in Alzheimers Disease [PMID: 30441866]

Interaction Information:

Comment Gut bacteria produce amino acids (i.e., gamma-amino butyric acid (GABA) and tryptophan), and monoamines (i.e., serotonin, histamine, and dopamine), which play a significant role in the brain as neurotransmitters, or as neurotransmitter precursors. These neuroactive products can target the CNS via the blood stream and can also influence neurons in the ENS (enteric nervous system).
Formal Description
Interaction-ID: 97577

environment

gut microbiota

increases_quantity of

drug/chemical compound

GABA