General Information:

Id: 8,676 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Homo sapiens
article
Reference: Lee SG et al.(2018) Fasting serum amino acids concentration is associated with insulin resistance and pro-inflammatory cytokines Diabetes Res. Clin. Pract. 140: 107-117 [PMID: 29601913]

Interaction Information:

Comment Twenty AAs, TNF-alpha, and IL-6 were analyzed in fasting serum samples from a total of 198 individuals (56 drug-naive patients with T2DM, 69 patients IFG (impaired fasting glucose), and 73 healthy controls). In addition to branched chain amino acids BCAAs, fasting serum AAs such as glutamic acid, lysine, phenylalanine, arginine, alanine, tyrosine, aspartic acid, were higher in patients with T2DM and intermediately elevated in patients with IFG compared with normoglycemic controls.
Formal Description
Interaction-ID: 90137

increases_quantity of

drug/chemical compound

Aspartate

in fasting serum; of patients with T2DM compared to healthy controls