General Information:

Id: 7,368 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
BTO:0000142 brain
article/cited
Reference: Hull J et al.(2015) Regional Increase in the Expression of the BCAT Proteins in Alzheimers Disease Brain: Implications in Glutamate Toxicity J. Alzheimers Dis. 45: 891-905 [PMID: 25633671]

Interaction Information:

Comment In humans and rodents, hBCATc is predominantly found in the soma and proximal dendrites of glutamatergic and GABAergic neuronal cells, in keeping with its role in contributing to the storage and metabolic pools of glutamate, which is in turn decarboxylated in GABAergic neurons to form GABA. (cited)
Formal Description
Interaction-ID: 72597

drug/chemical compound

Glutamate

affects_quantity of

drug/chemical compound

GABA