General Information:

Id: 670 (click here to show other Interactions for entry)
Diseases: Status epilepticus
Rattus norvegicus
Sprague-Dawley
BTO: 0000601 hippocampus
article
Reference: Wang HP et al.(2009) [Effects of edaravone on the expression of interleukin-1beta, nuclear factor-kappaB and neuron apoptosis in juvenile rat hippocampus after status convulsion] Zhonghua Er Ke Za Zhi 47: 575-580 [PMID: 19951488]

Interaction Information:

Comment The edaravone inhibited expression of IL-1beta and NF-kappaB in pilocarpine-induced seizures in rat hippocampus, reduced the number of neuronal apoptosis.
Formal Description
Interaction-ID: 3587

drug/chemical compound

Edaravone

decreases_activity of

in lithium-pilocarpine model