General Information:

Id: 6,438 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type I - [OMIM]
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Rattus norvegicus
male
streptozotocin-induced diabetic rat
article
Reference: Bahmani F et al.(2012) Glycine therapy inhibits the progression of cataract in streptozotocin-induced diabetic rats Mol. Vis. 18: 439-448 [PMID: 22355255]

Interaction Information:

Comment The results indicated that the oral administration of Gly significantly delayed the onset and the progression of diabetic cataract in rats. These effects were due to its antiglycating action and to a lesser extent, due to the inhibition of oxidative stress and polyol pathway.
Formal Description
Interaction-ID: 60797

drug/chemical compound

Glycine

decreases_activity of

process

polyol pathway

Drugbank entries Show/Hide entries for Glycine