General Information:

Id: 6,331 (click here to show other Interactions for entry)
Diseases: Hepatocellular carcinoma - [OMIM]
Homo sapiens
article
Reference: Soll C et al.(2010) Serotonin promotes tumor growth in human hepatocellular cancer Hepatology 51: 1244-1254 [PMID: 20099302]

Interaction Information:

Comment During starvation hepatocellular carcinoma cells exhibited characteristics of autophagy, which disappeared in serotonin-treated cells.
Formal Description
Interaction-ID: 59397

drug/chemical compound

Serotonin

decreases_activity of

process

autophagy

in Huh7 and HepG2 hepatocellular cancer cells; in response to starvation