General Information:

Id: 5,416 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
article
Reference: Yadav VK et al.(2008) Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum Cell 135: 825-837 [PMID: 19041748]

Interaction Information:

Comment Serotonin acts on osteoblasts through the Htr1b receptor and CREB to inhibit their proliferation.
Formal Description
Interaction-ID: 52910

drug/chemical compound

Serotonin

decreases_activity of

process

osteoblast proliferation