CIDeRplusGeneral Information:
| Id: | 5,024 (click here to show other Interactions for entry) |
| Diseases: |
Neurological
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| Homo sapiens | |
| article | |
| Reference: | Furukawa H et al.(2005) Subunit arrangement and function in NMDA receptors Nature 438: 185-192 [PMID: 16281028] |
Interaction Information:
| Comment | NMDA (N-methyl-D-aspartate) receptors are heteromeric ion channels that for activation require binding of glycine and glutamate to the NR1 and NR2 subunits, respectively. NMDA receptor function is characterized by slow channel opening and deactivation, and the resulting influx of cations initiates signal transduction cascades that are crucial to higher functions including learning and memory. |
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Formal Description Interaction-ID: 49586 |
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| Drugbank entries | Show/Hide entries for Glycine or GRIN1 |