General Information:
Id: | 4,940 (click here to show other Interactions for entry) |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
Homo sapiens | |
article | |
Reference: | Mittelstrass K et al.(2011) Discovery of sexual dimorphisms in metabolic and genetic biomarkers PLoS Genet. 7 [PMID: 21852955] |
Interaction Information:
Comment | All phenotypic analysis steps were performed on population-based cohort data from KORA F4 (1452 males, 1552 females) and KORA F3 (197 males, 180 females) with fasting serum concentrations of 131 metabolites. A combined meta-analysis of KORA F4 and KORA F3 revealed 113 metabolites with a significant effect of sex. The linear regression analysis showed that the concentrations of most amino acids were significantly higher in males except for the concentrations of glycine and serine which displayed higher concentrations in females. |
Formal Description Interaction-ID: 49024 |
phenotype sex affects_quantity of drug/chemical compound |
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