General Information:

Id: 4,767 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Metabolic
Rattus norvegicus
article/cited
Reference: Breard M et al.(2007) The endogenous neurotransmitter, serotonin, modifies neuronal nitric oxide synthase activities Free Radic. Res. 41: 413-423 [PMID: 17454123]

Interaction Information:

Comment 5HT induces an increase in nNOS activity under conditions where nNOS was shown to produce mainly H2O2 (in the absence of arginine and presence of BH4).
Formal Description
Interaction-ID: 47196

drug/chemical compound

Serotonin

increases_activity of

gene/protein

NOS1

in the absence of arginine
Drugbank entries Show/Hide entries for NOS1