General Information:

Id: 4,523 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Metabolic
Rattus norvegicus
male
Sprague-Dawley rat
aorta, heart tissue, smooth muscle cell (SMC)
article
Reference: El Midaoui A et al.(2006) Modulation of cardiac and aortic peroxisome proliferator-activated receptor-gamma expression by oxidative stress in chronically glucose-fed rats Am. J. Hypertens. 19: 407-412 [PMID: 16580578]

Interaction Information:

Comment Chronic glucose feeding (10% glucose in addition to normal chow diet for 4 weeks) resulted in a significant elevation of insulin resistance index, as expressed by HOMA. Subsequent treatment with alpha-lipoic acid attenuated this increase.
Formal Description
Interaction-ID: 45273

drug/chemical compound

Lipoate

decreases_activity of

disease

Insulin resistance