General Information:

Id: 441 (click here to show other Interactions for entry)
Diseases: Epilepsy
Rattus norvegicus
Sprague-Dawley
BTO:0003036 hippocampal cell line
article
Reference: Pal S et al.(2001) Epileptogenesis induces long-term alterations in intracellular calcium release and sequestration mechanisms in the hippocampal neuronal culture model of epilepsy. Cell Calcium 30: 285-296 [PMID: 11587552]

Interaction Information:

Comment A period of 30 min after the stimulus, control cells recovered to basal levels of [Ca2+]i that were not statistically significantly different from the initial levels prior to glutamate treatment. However, the [Ca2+]i levels in the epileptic cells were still slightly elevated above initial base line levels 40 min after the glutamate stimulatio.
Formal Description
Interaction-ID: 13796

drug/chemical compound

Glutamate

increases_quantity of

drug/chemical compound

Ca2+

in epileptic neurons