General Information:

Id: 4,113 (click here to show other Interactions for entry)
Diseases: Major depressive disorder - [OMIM]
Mus musculus
BTO:0000478 forebrain
article
Reference: Guo M et al.(2012) Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression Transl Psychiatry 2: E83 [PMID: 22408745]

Interaction Information:

Comment In addition, loss of Lepr in forebrain glutamatergic neurons facilitates NMDA-induced hippocampal long-term synaptic depression (LTD).
Formal Description
Interaction-ID: 42410

drug/chemical compound

Glutamate

interacts (colocalizes) with

complex/PPI

NMDA receptor complex