CIDeRplusGeneral Information:
| Id: | 3,977 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
| Homo sapiens | |
| article | |
| Reference: | Bajoria R et al.(2002) Placenta as a link between amino acids, insulin-IGF axis, and low birth weight: evidence from twin studies J. Clin. Endocrinol. Metab. 87: 308-315 [PMID: 11788666] |
Interaction Information:
| Comment | The study determined the association between fetal nutrition and the insulin-IGF axis by measuring the plasma concentrations of amino acids, insulin, IGF-I and IGF-binding protein-1 (IGFBP-1) in maternal and cord blood from gestational age-matched dichorionic (DC) twins with (n = 10) and without discordant birth weights (n = 10). In the growth-restricted (IUGR) twins, fetal concentrations of total essential, nonessential, and branched chain amino acids were lower than those in the appropriate for gestational age co-twins and concordant twin pairs. |
|
Formal Description Interaction-ID: 40437 |
phenotype decreases_quantity of drug/chemical compound |