General Information:
Id: | 3,651 (click here to show other Interactions for entry) |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
Homo sapiens | |
article | |
Reference: | Wang-Sattler R et al.(2012) Novel biomarkers for pre-diabetes identified by metabolomics Mol. Syst. Biol. 8: 615 [PMID: 23010998] |
Interaction Information:
Comment | To investigate the underlying molecular mechanism for the three identified IGT metabolites, their associations with T2D-related genes were studied by analyzing protein-metabolite interaction networks. In all, 7 out of the 46 known T2D-related genes (PPARG, TCF7L2, HNF1A, GCK, IGF1, IRS1 and IDE) were linked to these metabolites through related enzymes or proteins. |
Formal Description Interaction-ID: 34716 |
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Drugbank entries | Show/Hide entries for GCK or Glycine |