General Information:

Id: 3,651 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
article
Reference: Wang-Sattler R et al.(2012) Novel biomarkers for pre-diabetes identified by metabolomics Mol. Syst. Biol. 8: 615 [PMID: 23010998]

Interaction Information:

Comment To investigate the underlying molecular mechanism for the three identified IGT metabolites, their associations with T2D-related genes were studied by analyzing protein-metabolite interaction networks. In all, 7 out of the 46 known T2D-related genes (PPARG, TCF7L2, HNF1A, GCK, IGF1, IRS1 and IDE) were linked to these metabolites through related enzymes or proteins.
Formal Description
Interaction-ID: 34713

gene/protein

PPARG

affects_quantity of

drug/chemical compound

Glycine

Drugbank entries Show/Hide entries for PPARG or Glycine