CIDeRplusGeneral Information:
| Id: | 3,651 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
| Homo sapiens | |
| article | |
| Reference: | Wang-Sattler R et al.(2012) Novel biomarkers for pre-diabetes identified by metabolomics Mol. Syst. Biol. 8: 615 [PMID: 23010998] |
Interaction Information:
| Comment | The study revealed significant metabolic variation in pre-diabetic individuals that are distinct from known diabetes risk indicators, such as glycosylated hemoglobin levels, fasting glucose and insulin. The study identified three metabolites (glycine, lysophosphatidylcholine (LPC) (18:2) and acetylcarnitine) that had significantly altered levels in IGT individuals as compared to those with normal glucose tolerance. Lower levels of glycine and LPC were found to be predictors not only for IGT but also for T2D. |
|
Formal Description Interaction-ID: 34676 |
phenotype decreases_quantity of drug/chemical compound |
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