CIDeRplusGeneral Information:
| Id: | 3,561 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
| Homo sapiens | |
| article | |
| Reference: | Huffman KM et al.(2012) Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial PLoS ONE 7 [PMID: 22523532] |
Interaction Information:
| Comment | Using PCA to analyze changes in the fasting-to-postprandial difference (FPPD), we identified single components for FPPD for each of the major analyte modules, free fatty acids FFA, acylcarnitines AC, and amino acids AA, with eigenvalues of 6.37, 8.67, and 7.88 respectively, explaining 80%, 20% and 53% of the variance in the component. At the initial assessment, individual FFA and AC metabolites generally decreased from fasting to the postprandial state, particularly those that loaded heavily as part of the FFA and AC components. In contrast, individual AA concentrations increased in the transition to the postprandial state. |
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Formal Description Interaction-ID: 33171 |
environment feeding after fasting increases_quantity of drug/chemical compound |
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