CIDeRplusGeneral Information:
| Id: | 3,512 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance Obesity - [OMIM] |
| Homo sapiens | |
| article | |
| Reference: | Newgard CB et al.(2009) A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance Cell Metab. 9: 311-326 [PMID: 19356713] |
Interaction Information:
| Comment | Among a total of 16 amino acids measured in the serum, 7 were not different in obese versus lean subjects (citrulline, histidine, methionine, ornithine, proline, serine, tryptophan). Eight other amino acids were dramatically elevated in obese versus lean participants (alanine, valine, leucine/isoleucine, phenylalanine, tyrosine, glutamate/ glutamine, aspartate/asparagine, arginine), whereas glycine levels were lower in obese subjects. |
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Formal Description Interaction-ID: 32698 |
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