General Information:

Id: 3,438 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Metabolic syndrome
Obesity - [OMIM]
Rattus norvegicus
male
article
Reference: Sampey BP et al.(2012) Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation PLoS ONE 7 [PMID: 22701716]

Interaction Information:

Comment The influence of Cafeteria diets (CAF) consisting of nutrient poor human junk food was investigated. Supervised cluster analysis was performed to elucidate patterns of serum metabolic changes in CAF vs. SC-fed animals. This cluster analysis implicates upregulation of many NEFAs and acylcarnitine species with downregulation of several amino acids, arachidonoyl carnitine (C20:4), and short chain acylcarnitines in CAF-fed rats. Accumulation of acylcarnitines is indicative of inefficient beta-oxidation and mitochondrial dysfunction.
Formal Description
Interaction-ID: 31967

environment

cafeteria diet

increases_quantity of

drug/chemical compound

Glycine

in blood serum
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