CIDeRplusGeneral Information:
| Id: | 2,183 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
| Rattus norvegicus | |
| male | |
| 12-wk-old spontaneously hypertensive rats (SHR/NHsd, haplotype RT1k) | |
| article | |
| Reference: | Potenza MA et al.(2005) Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance between NO and ET-1 production Am. J. Physiol. Heart Circ. Physiol. 289: H813-H822 [PMID: 15792994] |
Interaction Information:
| Comment | Preincubation of arteries with insulin significantly reduced the contractile effect of norepinephrine (NE) by 20% in WKY but not SHR rats. |
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Formal Description Interaction-ID: 18288 |
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