CIDeRplusGeneral Information:
| Id: | 1,823 (click here to show other Interactions for entry) |
| Diseases: |
Alzheimer disease
- [OMIM]
|
| Homo sapiens | |
| BTO:0000258 choroid plexus | |
| article | |
| Reference: | Vargas T et al.(2010) Abeta accumulation in choroid plexus is associated with mitochondrial-induced apoptosis Neurobiol. Aging 31: 1569-1581 [PMID: 18838197] |
Interaction Information:
| Comment | A sequence of pathological steps link Abeta accumulation in CP epithelium with an enhanced nitric oxide production, mitochondrial dysfunction, and up-regulation of matrix metalloproteinase-9, which ultimately lead to cell death, and probably to CSF barrier dysfunction. |
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Formal Description Interaction-ID: 13700 |
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