General Information:

Id: 1,680 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Rattus norvegicus
APPsw PC12 cell
article
Reference: Keil U et al.(2004) Elevated nitric oxide production mediates beta-amyloid-induced mitochondria failure Pol J Pharmacol 56: 631-634 [PMID: 15591653]

Interaction Information:

Comment APPsw PC12 cells showed increased NO levels, decreased cytochrome C oxidase activity and reduced ATP levels compared to wild-type APP bearing cells.
Formal Description
Interaction-ID: 12547

tissue/cell line

PC-12 cell

increases_quantity of

drug/chemical compound

NO