CIDeRplusGeneral Information:
| Id: | 1,531 (click here to show other Interactions for entry) |
| Diseases: |
Parkinson disease
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| Mammalia | |
| article/cited | |
| Reference: | Johansen JL et al.(2010) HIF prolyl hydroxylase inhibition increases cell viability and potentiates dopamine release in dopaminergic cells J. Neurochem. 115: 209-219 [PMID: 20649842] |
Interaction Information:
| Comment | Hypoxia induces tyrosine hydroxylase expression in substantia nigra, which is the rate-limiting enzyme in dopamine synthesis, resulting in elevated dopamine release. (cited information) |
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Formal Description Interaction-ID: 10916 |
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| Drugbank entries | Show/Hide entries for TH or Dopamine |