CIDeRplusGeneral Information:
| Id: | 1,403 (click here to show other Interactions for entry) |
| Diseases: |
Parkinson disease
|
| Mus musculus | |
| article | |
| Reference: | Taylor TN et al.(2009) Nonmotor symptoms of Parkinsons disease revealed in an animal model with reduced monoamine storage capacity J. Neurosci. 29: 8103-8113 [PMID: 19553450] |
Interaction Information:
| Comment | Mice with a 95% genetic reduction in vesicular monoamine transporter expression (VMAT2-deficient, VMAT2 LO) display progressive loss of striatal dopamine, L-DOPA-responsive motor deficits, alpha-synuclein accumulation, and nigral dopaminergic cell loss. |
|
Formal Description Interaction-ID: 9733 |
|
| Drugbank entries | Show/Hide entries for SLC18A2 or Dopamine |