General Information:

Id: 1,314 (click here to show other Interactions for entry)
Diseases: Epilepsy, temporal lobe
Mammalia
review
Reference: Waldbaum S and Patel M(2010) Mitochondria, oxidative stress, and temporal lobe epilepsy Epilepsy Res. 88: 23-45 [PMID: 19850449]

Interaction Information:

Comment Results from the pilocarpine model have demonstrated decreased activity of complexes I and IV, increased flux control of complex I and decreased respiration rates in CA1 and CA3 30 d post-treatment, with no changes detected in the dentate gyrus or parahippocampal gyrus.
Formal Description
Interaction-ID: 8978

drug/chemical compound

Pilocarpine

increases_activity of

phenotype

convulsive seizures

Drugbank entries Show/Hide entries for Pilocarpine