General Information:

Id: 1,106 (click here to show other Interactions for entry)
Diseases: Schizophrenia - [OMIM]
Homo sapiens
BTO:0002807 prefrontal cortex; BTO:0000484 frontal lobe
article
Reference: Tan HY et al.(2008) Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans J. Clin. Invest. 118: 2200-2208 [PMID: 18497887]

Interaction Information:

Comment The functional polymorphism (Val158Met) of the COMT gene leads to lower dopamine level.
Formal Description
Interaction-ID: 7058

decreases_quantity of

drug/chemical compound

Dopamine

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