CIDeRplusGeneral Information:
| Id: | 1,070 (click here to show other Interactions for entry) |
| Diseases: |
Parkinson disease
|
| Homo sapiens | |
| BTO:0000793 SH-SY5Y cell | |
| article | |
| Reference: | Lev N et al.(2009) DJ-1 protects against dopamine toxicity. J Neural Transm 116: 151-160 [PMID: 18974921] |
Interaction Information:
| Comment | Exposure of cells to dopamine caused increased intracellular ROS levels. Overexpression of DJ-1 significantly reduced intracellular ROS accumulation after dopamine exposure. |
|
Formal Description Interaction-ID: 6742 |
drug/chemical compound increases_quantity of drug/chemical compound Reactive oxygen species |
| Drugbank entries | Show/Hide entries for Dopamine |