2,123
|
17536 |
T3SS
|
|
increases_transport of
|
exoY
|
into the host cell
|
|
15695491
|
Pseudomonas aeruginosa diseases
|
2,299
|
19681 |
exoY
|
|
increases_quantity of
|
cAMP
|
in cytosolic compartment
|
19684 |
exoY
|
|
decreases_activity of
|
establishment of endothelial barrier
|
|
19692 |
exoY
|
|
increases_activity of
|
MAPT
|
|
19713 |
exoY
|
|
increases_phosphorylation of
|
MAPT
|
at Ser 214
|
|
21478251
|
Pseudomonas aeruginosa diseases
|
2,336
|
20417 |
exoY
|
|
increases_quantity of
|
cAMP
|
in intracellular host cell compartment
|
|
19680249
|
Pseudomonas aeruginosa diseases
|
2,346
|
20567 |
exoY
|
|
increases_expression of
|
IL11
|
|
20568 |
exoY
|
|
decreases_expression of
|
FGG
|
|
20569 |
exoY
|
|
decreases_expression of
|
FGB
|
|
20570 |
exoY
|
|
decreases_expression of
|
ANXA13
|
|
20571 |
exoY
|
|
decreases_expression of
|
VTN
|
|
20572 |
exoY
|
|
decreases_expression of
|
S100P
|
|
20573 |
exoY
|
|
decreases_expression of
|
ERBB3
|
|
20574 |
exoY
|
|
decreases_expression of
|
ABCC5
|
|
20575 |
exoY
|
|
decreases_expression of
|
CEACAM5
|
|
20576 |
exoY
|
|
decreases_expression of
|
MUC5AC
|
|
20577 |
exoY
|
|
decreases_expression of
|
GYPE
|
|
|
16207250
|
Pseudomonas aeruginosa diseases
|
2,354
|
20593 |
exsA
|
|
increases_expression of
|
exoY
|
|
|
15901720
|
Pseudomonas aeruginosa diseases
|
2,464
|
23034 |
T3SS
|
|
increases_transport of
|
exoY
|
into the host cell
|
|
20947426
|
Pseudomonas aeruginosa diseases
|
2,518
|
23443 |
exoY
|
NOT |
interacts (colocalizes) with
|
CALM1
|
|
23444 |
CALM1
|
NOT |
affects_activity of
|
exoY
|
|
|
21517912
|
Pseudomonas aeruginosa diseases
|
2,586
|
24367 |
T3SS
|
|
increases_transport of
|
exoY
|
into the host cell
|
|
21833328
|
Pseudomonas aeruginosa diseases
|
3,006
|
27371 |
T3SS
|
|
increases_transport of
|
exoY
|
in A459, BJAB, Jurkat, differentiated HL-60 and U937 cells
|
27373 |
T3SS
|
NOT |
affects transport of
|
exoY
|
in undifferentiated HL-60 or U937 cells
|
|
22299042
|
Pseudomonas aeruginosa diseases
|
4,475
|
45045 |
exoY
|
|
increases_activity of
|
membrane bleb niche formation
|
in human corneal epithelial cells (hTCEpi); only to a low extend
|
|
20732998
|
Pseudomonas aeruginosa diseases
|
4,506
|
45100 |
exoY
|
|
increases_activity of
|
membrane bleb niche formation
|
requiring adenylate cyclase activity of ExoY
|
45101 |
exoY
|
NOT |
increases_activity of
|
P. aeruginosa intracellular replication
|
in membrane bleb niches
|
|
21843628
|
Pseudomonas aeruginosa diseases
|
4,507
|
45102 |
exoY
|
|
increases_activity of
|
P. aeruginosa infection
|
as shown in a mouse model 24 h and 48 h post-inoculation
|
|
21843628
|
Pseudomonas aeruginosa diseases
|
4,943
|
48854 |
exoY
|
NOT |
decreases_activity of
|
establishment of endothelial barrier
|
in primary endothelial cells
|
48857 |
exoY
|
NOT |
decreases_activity of
|
focal adhesion assembly
|
in primary endothelial cells
|
48858 |
exoY
|
NOT |
decreases_activity of
|
actin cytoskeleton organization
|
in primary endothelial cells
|
|
23974244
|
Pseudomonas aeruginosa diseases
|
5,267
|
51349 |
exoY
|
|
decreases_quantity of
|
microtubule cytoskeleton
|
|
51359 |
exoY
|
|
decreases_activity of
|
microtubule cytoskeleton organization
|
|
51371 |
exoY
|
|
increases_phosphorylation of
|
MAPT
|
at Ser-214
|
51372 |
exoY
|
|
decreases_activity of
|
establishment of endothelial barrier
|
|
51489 |
exoY
|
NOT |
affects_activity of
|
centrosome-templated microtubule nucleation
|
|
|
24023939
|
Pseudomonas aeruginosa diseases
|
6,402
|
60381 |
exoY
|
NOT |
affects_activity of
|
biofilm formation
|
as shown on MDCK epithelial cells and in a murine model of acute neumonia
|
|
25375398
|
Pseudomonas aeruginosa diseases
|