2,024
|
16087 |
Coxiella burnetii infection
|
|
increases_activity of
|
Q fever, acute
|
|
16146 |
Doxycycline
|
|
decreases_activity of
|
Q fever, acute
|
|
17575 |
Coxiella burnetii infection
|
|
increases_activity of
|
Q fever, chronic
|
|
|
21030501
|
Q fever
|
2,061
|
35043 |
Coxiella burnetii infection
|
|
increases_quantity of
|
IFNG
|
in lymphocytes from vaccinated and convalescent humans
|
35045 |
IFNG
|
|
decreases_activity of
|
Coxiella burnetii replication
|
|
35052 |
IFNG
|
|
increases_quantity of
|
Reactive oxygen species
|
|
35053 |
IFNG
|
|
increases_quantity of
|
Reactive nitrogen species
|
|
35073 |
Q fever, acute
|
|
increases_activity of
|
T cell mediated immunity
|
|
35074 |
T cell mediated immunity
|
|
increases_quantity of
|
IFNG
|
|
|
18813881
|
Q fever
|
2,103
|
17170 |
Q fever, acute
|
|
increases_activity of
|
granuloma formation
|
in human monocytes and macrophages
|
17316 |
Q fever, acute
|
|
decreases_activity of
|
pathogen survival
|
in human monocytes
|
|
19538264
|
Q fever
|
2,579
|
24287 |
Q fever, acute
|
|
cooccurs with
|
Febrile flu-like illness
|
predominant form of acute Q fever
|
24288 |
Q fever, acute
|
|
cooccurs with
|
Pneumonia
|
|
24289 |
Q fever, acute
|
|
cooccurs with
|
Hepatitis
|
|
24290 |
Q fever, acute
|
|
cooccurs with
|
Neurological sequelae
|
|
24291 |
Q fever, acute
|
|
cooccurs with
|
Myocarditis
|
|
24320 |
Doxycycline
|
|
decreases_activity of
|
Q fever, acute
|
|
24321 |
Ofloxacin
|
|
decreases_activity of
|
Neurological sequelae
|
administered to adults with meningoencephalitis
|
24322 |
Pefloxacin
|
|
decreases_activity of
|
Neurological sequelae
|
administered to adults with meningoencephalitis
|
24323 |
Co-Trimoxazole
|
|
decreases_activity of
|
Q fever, acute
|
|
24324 |
Rifampicin
|
|
decreases_activity of
|
Q fever, acute
|
|
24325 |
Clarithromycin
|
|
decreases_activity of
|
Pneumonia
|
|
24326 |
Roxithromycin
|
|
decreases_activity of
|
Pneumonia
|
|
24338 |
Co-Trimoxazole
|
|
decreases_activity of
|
abnormal spontaneous abortion rate
|
|
36539 |
Co-Trimoxazole
|
NOT |
decreases_activity of
|
Q fever, chronic
|
|
|
20455682
|
Q fever
|
3,544
|
32986 |
Q fever, acute
|
|
increases_quantity of
|
IFNG
|
|
32987 |
Q fever, chronic
|
NOT |
increases_quantity of
|
IFNG
|
|
|
22711631
|
Q fever
|
3,653
|
34759 |
monocyte activation
|
|
increases_activity of
|
M1 polarization
|
in response to C. burnetii infection
|
34764 |
macrophage activation
|
|
increases_activity of
|
atypical M2 polarization
|
in response to C. burnetii infection
|
34766 |
atypical M2 polarization
|
|
increases_quantity of
|
IL10
|
in macrophages; in response to C. burnetii infection
|
34767 |
atypical M2 polarization
|
|
increases_quantity of
|
TGFB1
|
in macrophages; in response to C. burnetii infection
|
34768 |
atypical M2 polarization
|
|
increases_quantity of
|
CCL18
|
in macrophages; in response to C. burnetii infection
|
34769 |
atypical M2 polarization
|
|
increases_quantity of
|
MRC1
|
in macrophages; in response to C. burnetii infection
|
34770 |
atypical M2 polarization
|
|
increases_quantity of
|
IL6
|
in macrophages; in response to C. burnetii infection
|
34771 |
atypical M2 polarization
|
|
increases_quantity of
|
CXCL8
|
in response to C. burnetii infection
|
34772 |
atypical M2 polarization
|
|
increases_quantity of
|
ARG1
|
in macrophages; in response to C. burnetii infection
|
34773 |
M1 polarization
|
|
increases_quantity of
|
TNF
|
in monocytes; in response to C. burnetii infection
|
34774 |
M1 polarization
|
|
increases_quantity of
|
IL6
|
in monocytes; in response to C. burnetii infection
|
34775 |
M1 polarization
|
|
increases_quantity of
|
IL12
|
in monocytes; in response to C. burnetii infection
|
34776 |
M1 polarization
|
|
increases_quantity of
|
CD80
|
in monocytes; in response to C. burnetii infection
|
34777 |
M1 polarization
|
|
increases_quantity of
|
CCR7
|
in monocytes; in response to C. burnetii infection
|
34778 |
M1 polarization
|
|
increases_quantity of
|
IFNG
|
in monocytes; in response to C. burnetii infection
|
34779 |
M1 polarization
|
|
increases_quantity of
|
Reactive nitrogen species
|
in response to C. burnetii infection
|
34787 |
IL10
|
|
increases_activity of
|
pathogen survival
|
|
34788 |
atypical M2 polarization
|
NOT |
increases_quantity of
|
TNF
|
in macrophages; in response to C. burnetii infection
|
34789 |
atypical M2 polarization
|
NOT |
increases_quantity of
|
IL12
|
in macrophages; in response to C. burnetii infection
|
34790 |
atypical M2 polarization
|
NOT |
increases_quantity of
|
CD80
|
in macrophages; in response to C. burnetii infection
|
34791 |
atypical M2 polarization
|
NOT |
increases_quantity of
|
CCR7
|
in macrophages; in response to C. burnetii infection
|
34792 |
atypical M2 polarization
|
NOT |
increases_quantity of
|
Reactive nitrogen species
|
in macrophages; in response to C. burnetii infection
|
34962 |
atypical M2 polarization
|
NOT |
decreases_activity of
|
Coxiella burnetii replication
|
in macrophages
|
34963 |
M1 polarization
|
|
decreases_activity of
|
Coxiella burnetii replication
|
in monocytes
|
34975 |
Q fever, chronic
|
|
increases_activity of
|
engulfment of apoptotic cell
|
|
34976 |
Q fever, acute
|
|
decreases_activity of
|
engulfment of apoptotic cell
|
|
36492 |
Q fever, acute
|
NOT |
increases_quantity of
|
FOXP3
|
in regulatory T cell subsets
|
|
22711638
|
Q fever
|
3,660
|
34903 |
Coxiella burnetii infection
|
|
increases_activity of
|
Q fever, acute
|
|
34908 |
Coxiella burnetii infection
|
|
increases_activity of
|
Q fever, chronic
|
|
34910 |
monocyte activation
|
|
increases_activity of
|
M1 polarization
|
in response to C. burnetii infection
|
34912 |
macrophage activation
|
|
increases_activity of
|
atypical M2 polarization
|
in response to C. burnetii infection
|
34914 |
Q fever, acute
|
|
increases_activity of
|
M1 polarization
|
in monocytes
|
34916 |
Q fever, acute
|
|
increases_activity of
|
atypical M2 polarization
|
in macrophages
|
34921 |
atypical M2 polarization
|
|
increases_quantity of
|
IL10
|
in macrophages; in response to C. burnetii infection
|
34922 |
atypical M2 polarization
|
|
increases_quantity of
|
TGFB1
|
in macrophages; in response to C. burnetii infection
|
34923 |
atypical M2 polarization
|
|
increases_quantity of
|
CCL18
|
in macrophages; in response to C. burnetii infection
|
34924 |
atypical M2 polarization
|
|
increases_quantity of
|
MRC1
|
in macrophages; in response to C. burnetii infection
|
34925 |
atypical M2 polarization
|
|
increases_quantity of
|
ARG1
|
in macrophages; in response to C. burnetii infection
|
34926 |
atypical M2 polarization
|
|
increases_quantity of
|
IL6
|
in macrophages; in response to C. burnetii infection
|
34927 |
atypical M2 polarization
|
|
increases_quantity of
|
CXCL8
|
in macrophages; in response to C. burnetii infection
|
34928 |
atypical M2 polarization
|
NOT |
increases_quantity of
|
TNF
|
in macrophages; in response to C. burnetii infection
|
34931 |
atypical M2 polarization
|
NOT |
increases_quantity of
|
IL12
|
in macrophages; in response to C. burnetii infection
|
34932 |
atypical M2 polarization
|
NOT |
increases_quantity of
|
CD80
|
in macrophages; in response to C. burnetii infection
|
34933 |
atypical M2 polarization
|
NOT |
increases_quantity of
|
CCR7
|
in macrophages; in response to C. burnetii infection
|
34934 |
atypical M2 polarization
|
NOT |
increases_quantity of
|
Reactive nitrogen species
|
in macrophages; in response to C. burnetii infection
|
34935 |
atypical M2 polarization
|
NOT |
decreases_activity of
|
Coxiella burnetii replication
|
in macrophages; during acute Q fever
|
34936 |
M1 polarization
|
|
increases_quantity of
|
TNF
|
in monocytes; in response to C. burnetii infection
|
34937 |
M1 polarization
|
|
increases_quantity of
|
IL6
|
in monocytes; in response to C. burnetii infection
|
34938 |
M1 polarization
|
|
increases_quantity of
|
IL12
|
in monocytes; in response to C. burnetii infection
|
34939 |
M1 polarization
|
|
increases_quantity of
|
CCR7
|
in monocytes; in response to C. burnetii infection
|
34940 |
M1 polarization
|
|
increases_quantity of
|
IFNG
|
in monocytes; in response to C. burnetii infection
|
34961 |
M1 polarization
|
|
decreases_activity of
|
Coxiella burnetii replication
|
in monocytes
|
|
18768823
|
Q fever
|
3,688
|
35407 |
IFNG
|
|
increases_activity of
|
phagosome-lysosome fusion
|
|
35409 |
IFNG
|
|
affects_activity of
|
phagosome acidification
|
|
35478 |
Q fever, chronic
|
NOT |
increases_activity of
|
T cell mediated immunity
|
|
35480 |
Q fever, acute
|
|
increases_activity of
|
T cell mediated immunity
|
|
|
22711637
|
Q fever
|
3,744
|
36383 |
Q fever, acute
|
|
increases_expression of
|
PER2
|
in men to a significant level
|
36384 |
Q fever, chronic
|
NOT |
increases_expression of
|
PER2
|
in men
|
36385 |
Q fever, acute
|
NOT |
increases_expression of
|
PER2
|
in women
|
|
22984121
|
Q fever
|
3,751
|
36477 |
Q fever, acute
|
|
cooccurs with
|
Febrile flu-like illness
|
like high fever, severe headache, night sweating, nausea, diarrhoea
|
36479 |
Q fever, acute
|
|
cooccurs with
|
Pneumonia
|
|
36480 |
Q fever, acute
|
|
cooccurs with
|
Hepatitis
|
|
36481 |
Q fever, acute
|
|
cooccurs with
|
Myocarditis
|
|
36482 |
Q fever, acute
|
|
cooccurs with
|
Pericarditis
|
|
36483 |
Q fever, acute
|
|
cooccurs with
|
Neurological sequelae
|
|
36484 |
Q fever, acute
|
|
cooccurs with
|
weight loss
|
|
36490 |
Q fever, acute
|
|
cooccurs with
|
Q fever fatigue syndrome, QFS
|
|
|
22711640
|
Q fever
|
3,760
|
36580 |
Q fever, acute
|
|
increases_activity of
|
abnormal spontaneous abortion rate
|
|
36581 |
QpDV plasmid
|
|
increases_activity of
|
Q fever, acute
|
|
36586 |
Co-Trimoxazole
|
|
decreases_activity of
|
Q fever, acute
|
|
36587 |
Co-Trimoxazole
|
|
decreases_activity of
|
abnormal spontaneous abortion rate
|
|
|
23052984
|
Q fever
|
3,769
|
36727 |
Q fever, chronic
|
|
increases_quantity of
|
CCL5
|
in plasma of patients with chronic Q fever
|
36738 |
Q fever, chronic
|
|
increases_quantity of
|
CCL2
|
in plasma of patients with chronic Q fever
|
36739 |
Q fever, acute
|
NOT |
increases_quantity of
|
CCL5
|
in plasma of patients with acute Q fever
|
36740 |
Q fever, acute
|
NOT |
increases_quantity of
|
CCL2
|
in plasma of patients with acute Q fever
|
|
17353158
|
Q fever
|
3,782
|
37239 |
Coxiella burnetii infection
|
|
is localized in
|
lung
|
|
37240 |
Coxiella burnetii infection
|
|
is localized in
|
liver
|
|
37241 |
Coxiella burnetii infection
|
|
is localized in
|
spleen
|
|
37242 |
Coxiella burnetii infection
|
|
is localized in
|
amniotic fluid
|
|
37243 |
Coxiella burnetii infection
|
|
is localized in
|
placenta
|
|
37250 |
Q fever, acute
|
|
cooccurs with
|
Meningitis
|
in rare cases
|
37251 |
Q fever, acute
|
|
cooccurs with
|
Meningoencephalitis
|
in rare cases
|
37252 |
Q fever, acute
|
|
cooccurs with
|
Guillain-Barre syndrome
|
in rare cases
|
37253 |
Arrhythmia
|
|
cooccurs with
|
Myocarditis
|
in rare cases
|
37256 |
Tachycardia
|
|
cooccurs with
|
Myocarditis
|
in rare cases
|
37257 |
Hypoxemia
|
|
cooccurs with
|
Myocarditis
|
in rare cases
|
37276 |
Doxycycline
|
|
decreases_activity of
|
Q fever, acute
|
|
37279 |
Fluoroquinolone
|
|
decreases_activity of
|
Q fever, acute
|
|
37285 |
Pefloxacin
|
|
decreases_activity of
|
Q fever, acute
|
|
37287 |
Fluoroquinolone
|
|
decreases_activity of
|
phagosome acidification
|
|
37289 |
Fluoroquinolone
|
|
decreases_activity of
|
Meningoencephalitis
|
|
37291 |
Erythromycin
|
|
decreases_activity of
|
Q fever, acute
|
|
37303 |
Q fever, acute
|
|
increases_activity of
|
Pneumonia
|
as main clinical symptom in children
|
37305 |
Q fever, acute
|
|
increases_activity of
|
Meningitis
|
as main clinical symptom in children
|
37306 |
Q fever, acute
|
|
increases_activity of
|
Hepatitis
|
as rare clinical symptom in children
|
37307 |
Q fever, acute
|
|
increases_activity of
|
Febrile flu-like illness
|
in children
|
|
23163207
|
Q fever
|
3,797
|
37731 |
Q fever, acute
|
|
increases_activity of
|
skin lesions
|
|
|
15792739
|
Q fever
|
4,009
|
41149 |
QpH1 plasmid
|
|
increases_activity of
|
Q fever, acute
|
|
|
23687269
|
Q fever
|