|
2,370
|
| 20827 |
psrA
|
|
decreases_expression of
|
tle5
|
|
|
18524913
|
Pseudomonas aeruginosa diseases
|
|
2,464
|
| 24062 |
T6SS-HSI-1
|
|
increases_transport of
|
hcp1
|
into the host cell / into the extracellular medium; in patients with CF
|
| 24081 |
P. aeruginosa infection, chronic
|
|
increases_activity of
|
T6SS-HSI-1
|
|
| 24082 |
P. aeruginosa infection
|
|
increases_activity of
|
T6SS-HSI-2
|
|
| 24083 |
P. aeruginosa infection
|
|
increases_activity of
|
T6SS-HSI-3
|
|
|
20947426
|
Pseudomonas aeruginosa diseases
|
|
2,492
|
| 23250 |
T6SS-HSI-1
|
|
increases_transport of
|
tse1
|
into the host cell / into the extracellular medium
|
| 23251 |
T6SS-HSI-1
|
|
increases_transport of
|
tse2
|
into the host cell / into the extracellular medium
|
| 23252 |
T6SS-HSI-1
|
|
increases_transport of
|
tse3
|
into the host cell / into the extracellular medium
|
| 23254 |
tse2
|
|
affects_activity of
|
killing of other bacteria
|
|
| 24066 |
T6SS-HSI-1
|
|
increases_transport of
|
hcp1
|
into the host cell / into the extracellular medium
|
| 24067 |
T6SS-HSI-1
|
|
increases_transport of
|
vgrG1a
|
into the host cell / into the extracellular medium
|
| 28465 |
hcp1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28466 |
vgrG1a
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28467 |
vgrG1b
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28468 |
tssA1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28469 |
tssB1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28470 |
tssC1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28471 |
tagJ1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28472 |
tssE1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28473 |
tssF1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28474 |
tssG1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28475 |
clpV1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28476 |
tssK1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28477 |
icmF1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28478 |
tssL1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28479 |
tssJ1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
|
21811488
|
Pseudomonas aeruginosa diseases
|
|
2,555
|
| 23801 |
T6SS-HSI-1
|
|
increases_transport of
|
vgrG1a
|
into the extracellular medium
|
| 23802 |
T6SS-HSI-1
|
|
increases_transport of
|
vgrG1c
|
into the extracellular medium
|
| 23803 |
T6SS-HSI-1
|
|
increases_transport of
|
vgrG1b
|
into the extracellular medium
|
| 23823 |
retS
|
|
decreases_expression of
|
vgrG1a
|
|
| 23831 |
ladS
|
|
decreases_activity of
|
retS
|
if ladS is overexpressed
|
| 23836 |
ladS
|
|
increases_expression of
|
T6SS-HSI-1 complex
|
if ladS is overexpressed
|
| 23848 |
clpV1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 23880 |
vgrG1b
|
NOT |
affects transport of
|
hcp1
|
|
| 23882 |
vgrG1b
|
NOT |
affects transport of
|
vgrG1a
|
|
| 23886 |
vgrG1b
|
NOT |
affects transport of
|
vgrG1c
|
|
| 23894 |
vgrG1a
|
|
increases_transport of
|
hcp1
|
|
| 23898 |
vgrG1c
|
|
increases_transport of
|
hcp1
|
|
| 23903 |
vgrG1a
|
NOT |
affects transport of
|
vgrG1c
|
|
| 23906 |
vgrG1c
|
NOT |
affects transport of
|
vgrG1a
|
|
| 23927 |
clpV1
|
|
increases_transport of
|
vgrG1a
|
|
| 23928 |
clpV1
|
|
increases_transport of
|
vgrG1c
|
|
| 23929 |
vgrG1a
|
|
increases_transport of
|
tse3
|
|
| 23946 |
vgrG1b
|
|
increases_transport of
|
tse3
|
|
| 23950 |
vgrG1c
|
|
increases_transport of
|
tse3
|
|
| 24069 |
T6SS-HSI-1
|
|
increases_transport of
|
hcp1
|
|
| 27005 |
clpV1
|
NOT |
affects transport of
|
vgrG1b
|
|
| 27009 |
vgrG1a
|
|
interacts (colocalizes) with
|
vgrG1c
|
|
|
21325275
|
Pseudomonas aeruginosa diseases
|
|
2,565
|
| 24054 |
retS
|
|
decreases_expression of
|
T6SS-HSI-1 complex
|
|
| 24055 |
ladS
|
|
increases_expression of
|
T6SS-HSI-1 complex
|
|
| 24076 |
biofilm formation
|
|
increases_expression of
|
T6SS-HSI-1 complex
|
progressively during biofilm formation from attachment to maturation
|
| 24078 |
biofilm formation
|
|
increases_expression of
|
T6SS-HSI-3 complex
|
during the initial steps of biofilm development
|
| 24079 |
mvaT
|
|
decreases_expression of
|
T6SS-HSI-2 complex
|
DNA microarray approach
|
| 24084 |
mvaT
|
|
decreases_expression of
|
T6SS-HSI-3 complex
|
DNA microarray approach
|
| 24104 |
mvfR
|
|
increases_expression of
|
T6SS-HSI-2 complex
|
DNA microarray, RT-PCR appoach
|
| 24106 |
mvfR
|
|
increases_expression of
|
T6SS-HSI-3 complex
|
DNA microarray, RT-PCR appoach
|
| 24107 |
mvfR
|
|
decreases_expression of
|
T6SS-HSI-1 complex
|
DNA microarray, RT-PCR appoach
|
| 24119 |
psrA
|
|
affects_expression of
|
T6SS-HSI-2 complex
|
DNA microarray approach
|
| 28406 |
rsmA
|
|
decreases_expression of
|
T6SS-HSI-1 complex
|
DNA microarray approach
|
|
20511495
|
Pseudomonas aeruginosa diseases
|
|
2,568
|
| 24139 |
ppkA
|
|
increases_activity of
|
fha1
|
|
| 24140 |
ppkA
|
|
increases_phosphorylation of
|
fha1
|
|
| 24141 |
pppA
|
|
decreases_activity of
|
fha1
|
|
| 24142 |
pppA
|
|
decreases_phosphorylation of
|
fha1
|
|
| 24143 |
T6SS-HSI-1
|
|
increases_transport of
|
hcp1
|
|
| 24144 |
ppkA
|
|
increases_activity of
|
T6SS-HSI-1
|
|
| 24145 |
pppA
|
|
decreases_activity of
|
T6SS-HSI-1
|
|
| 24151 |
ppkA
|
|
increases_phosphorylation of
|
ppkA
|
|
| 24152 |
ppkA
|
|
interacts (colocalizes) with
|
ppkA
|
|
| 24153 |
fha1
|
|
increases_activity of
|
T6SS-HSI-1
|
|
| 24154 |
clpV1
|
|
increases_activity of
|
T6SS-HSI-1
|
|
| 24155 |
tagR1
|
|
increases_activity of
|
ppkA
|
|
|
19400797
|
Pseudomonas aeruginosa diseases
|
|
2,573
|
| 24200 |
T6SS-HSI-1
|
|
increases_transport of
|
tse1
|
|
| 24202 |
T6SS-HSI-1
|
|
increases_transport of
|
tse3
|
|
| 24203 |
tsi2
|
|
decreases_activity of
|
tse2
|
|
| 24204 |
tsi2
|
|
interacts (colocalizes) with
|
tse2
|
|
| 24205 |
tse2
|
|
affects_activity of
|
killing of other bacteria
|
analysed in S. cerevisiae, HeLa cells, Escherichia coli and Burkholderia thailandensis
|
| 24207 |
T6SS-HSI-1
|
|
increases_transport of
|
tse2
|
into bacterial cells
|
| 24210 |
T6SS-HSI-1
|
NOT |
increases_transport of
|
tse2
|
into eucaryotic cells
|
|
20114026
|
Pseudomonas aeruginosa diseases
|
|
2,592
|
| 24446 |
P. aeruginosa infection, chronic
|
|
increases_activity of
|
T6SS-HSI-1
|
in patients with CF
|
| 24479 |
rsmA
|
|
decreases_expression of
|
T6SS-HSI-1 complex
|
|
|
21955777
|
Pseudomonas aeruginosa diseases
|
|
2,595
|
| 24493 |
cdiGMP
|
|
increases_activity of
|
T6SS-HSI-1
|
if c-di-GMP levels are increased
|
| 24521 |
cdiGMP
|
|
increases_quantity of
|
hcp1
|
if c-di-GMP levels are increased
|
| 24548 |
wspR
|
|
increases_quantity of
|
cdiGMP
|
|
| 24552 |
tpbB
|
|
increases_quantity of
|
cdiGMP
|
|
| 24553 |
wspR
|
|
increases_activity of
|
T6SS-HSI-1
|
if wspR is overexpressed
|
| 24554 |
tpbB
|
|
increases_activity of
|
T6SS-HSI-1
|
if PA1120 is overexpressed
|
| 24557 |
PA2133
|
|
decreases_quantity of
|
cdiGMP
|
if PA2133 is overexpressed
|
| 24558 |
PA2133
|
|
increases_activity of
|
T3SS
|
if PA2133 is overexpressed
|
| 24559 |
PA2133
|
|
decreases_activity of
|
T6SS-HSI-1
|
if PA2133 is overexpressed
|
|
21955777
|
Pseudomonas aeruginosa diseases
|
|
2,706
|
| 25237 |
tse1
|
|
decreases_quantity of
|
peptidoglycan, exogenous
|
in the periplasm of recipient cell
|
| 25241 |
tse3
|
|
decreases_quantity of
|
peptidoglycan, exogenous
|
in the periplasm of recipient cell
|
| 25246 |
tse1
|
|
interacts (colocalizes) with
|
tsi1
|
|
| 25247 |
tse3
|
|
interacts (colocalizes) with
|
tsi3
|
|
| 25248 |
T6SS-HSI-1
|
|
increases_transport of
|
tse1
|
into periplasm of recipient cell
|
| 25249 |
T6SS-HSI-1
|
|
increases_transport of
|
tse3
|
into periplasm of recipient cell
|
| 25250 |
tsi1
|
|
decreases_activity of
|
tse1
|
|
| 25251 |
tsi3
|
|
decreases_activity of
|
tse3
|
|
| 25253 |
tse1
|
|
increases_activity of
|
killing of other bacteria
|
|
| 25254 |
tse3
|
|
increases_activity of
|
killing of other bacteria
|
|
|
21776080
|
Pseudomonas aeruginosa diseases
|
|
2,832
|
| 26135 |
LasR/I-3OC12-(HSL)-system
|
|
decreases_expression of
|
T6SS-HSI-1 complex
|
|
| 26139 |
biofilm formation
|
|
increases_activity of
|
T6SS-HSI-1
|
more than planktonic culture
|
| 26141 |
phosphorylation-dependent type VI secretion activation
|
|
increases_activity of
|
T6SS-HSI-1
|
|
| 26142 |
tagR1
|
|
affects_activity of
|
phosphorylation-dependent type VI secretion activation
|
|
| 26143 |
ppkA
|
|
affects_activity of
|
phosphorylation-dependent type VI secretion activation
|
|
| 26144 |
pppA
|
|
affects_activity of
|
phosphorylation-dependent type VI secretion activation
|
|
| 26145 |
fha1
|
|
affects_activity of
|
phosphorylation-dependent type VI secretion activation
|
|
| 26146 |
ppkA
|
|
increases_activity of
|
T6SS-HSI-1
|
|
| 26147 |
tagR1
|
|
increases_activity of
|
ppkA
|
|
| 26149 |
ppkA
|
|
increases_phosphorylation of
|
fha1
|
at Thr 362
|
| 26150 |
ppkA
|
|
interacts (colocalizes) with
|
fha1
|
|
| 26151 |
fha1
|
|
increases_activity of
|
T6SS-HSI-1
|
|
| 26152 |
fha1
|
|
interacts (colocalizes) with
|
clpV1
|
|
| 26154 |
pppA
|
|
decreases_activity of
|
phosphorylation-dependent type VI secretion activation
|
|
| 26157 |
pppA
|
|
decreases_phosphorylation of
|
fha1
|
|
|
22017253
|
Pseudomonas aeruginosa diseases
|
|
2,835
|
| 26158 |
tagF1
|
|
decreases_activity of
|
T6SS-HSI-1
|
by a phosphorylation-independent type VI secretion activation
|
| 26159 |
tagF1
|
|
affects_activity of
|
phosphorylation-independent type VI secretion activation
|
|
| 26160 |
tagF1
|
NOT |
affects_activity of
|
phosphorylation-dependent type VI secretion activation
|
|
| 26161 |
ppkA
|
NOT |
affects_activity of
|
phosphorylation-independent type VI secretion activation
|
|
| 26162 |
fha1
|
|
affects_activity of
|
phosphorylation-independent type VI secretion activation
|
but only in the not-phosphorylated form of fha1
|
| 26163 |
clpV1
|
|
affects_activity of
|
phosphorylation-independent type VI secretion activation
|
|
| 26164 |
clpV1
|
|
affects_activity of
|
phosphorylation-dependent type VI secretion activation
|
|
| 26165 |
biofilm formation
|
|
affects_activity of
|
phosphorylation-dependent type VI secretion activation
|
|
|
22017253
|
Pseudomonas aeruginosa diseases
|
|
2,851
|
| 26273 |
tssC1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 26274 |
biofilm formation
|
|
increases_quantity of
|
tssC1
|
|
| 26275 |
tssC1
|
|
increases_activity of
|
antibiotic resistance
|
biofilm-specific
|
| 26276 |
biofilm formation
|
|
increases_quantity of
|
hcp1
|
|
| 28174 |
biofilm formation
|
|
increases_activity of
|
T6SS-HSI-1
|
|
|
21784934
|
Pseudomonas aeruginosa diseases
|
|
3,088
|
| 28343 |
P. aeruginosa infection
|
|
increases_activity of
|
T6SS-HSI-2
|
|
| 28344 |
T6SS-HSI-2 complex
|
|
increases_activity of
|
T6SS-HSI-2
|
|
| 28345 |
P. aeruginosa infection
|
|
increases_activity of
|
T6SS-HSI-3
|
|
| 28346 |
T6SS-HSI-3 complex
|
|
increases_activity of
|
T6SS-HSI-3
|
|
| 28347 |
P. aeruginosa infection
|
|
increases_activity of
|
T6SS-HSI-1
|
|
| 28348 |
T6SS-HSI-1 complex
|
|
increases_activity of
|
T6SS-HSI-1
|
|
| 28352 |
hcp1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28353 |
T6SS-HSI-1
|
|
increases_transport of
|
hcp1
|
|
|
19497948
|
Pseudomonas aeruginosa diseases
|
|
3,089
|
| 28351 |
hcp2
|
|
is_part_of
|
T6SS-HSI-2 complex
|
|
| 28354 |
mvfR
|
|
increases_expression of
|
T6SS-HSI-2 complex
|
shown in a microarray and qRT-PCR approach
|
| 28355 |
LasR/I-3OC12-(HSL)-system
|
|
increases_expression of
|
T6SS-HSI-2 complex
|
shown in a microarray and qRT-PCR approach
|
| 28356 |
hcp3
|
|
is_part_of
|
T6SS-HSI-3, right operon
|
|
| 28357 |
mvfR
|
|
increases_expression of
|
T6SS-HSI-3 complex
|
shown in a microarray and qRT-PCR approach
|
| 28358 |
LasR/I-3OC12-(HSL)-system
|
|
increases_expression of
|
T6SS-HSI-3 complex
|
shown in a microarray and qRT-PCR approach
|
| 28359 |
hcp1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 28360 |
mvfR
|
|
decreases_expression of
|
T6SS-HSI-1 complex
|
shown in a microarray and qRT-PCR approach
|
| 28361 |
LasR/I-3OC12-(HSL)-system
|
|
decreases_expression of
|
T6SS-HSI-1 complex
|
shown in a microarray and qRT-PCR approach
|
| 28362 |
P. aeruginosa infection, acute
|
|
increases_activity of
|
T6SS-HSI-2
|
shown in Arabidopsis, acute mouse lung and acute mouse burn infection models
|
| 28363 |
P. aeruginosa infection, acute
|
|
increases_activity of
|
T6SS-HSI-3
|
shown in Arabidopsis, acute mouse lung and acute mouse burn infection models
|
| 28364 |
4CABA
|
|
decreases_expression of
|
T6SS-HSI-2 complex
|
shown in a microarray and qRT-PCR approach
|
| 28365 |
4CABA
|
|
decreases_expression of
|
T6SS-HSI-3 complex
|
shown in a microarray and qRT-PCR approach
|
| 28366 |
6CABA
|
|
decreases_expression of
|
T6SS-HSI-2 complex
|
shown in a microarray and qRT-PCR approach
|
| 28367 |
6CABA
|
|
decreases_expression of
|
T6SS-HSI-3 complex
|
shown in a microarray and qRT-PCR approach
|
| 28368 |
4CABA
|
|
decreases_activity of
|
mvfR
|
|
| 28369 |
6CABA
|
|
decreases_activity of
|
mvfR
|
|
| 28370 |
mvfR
|
|
increases_expression of
|
hcp2
|
shown in qRT-PCR approach
|
| 28371 |
lasR
|
|
increases_expression of
|
hcp2
|
shown in qRT-PCR approach
|
| 28373 |
mvfR
|
|
increases_expression of
|
hcp3
|
shown in qRT-PCR approach
|
| 28374 |
lasR
|
|
increases_expression of
|
hcp3
|
shown in qRT-PCR approach
|
| 28375 |
mvfR
|
|
decreases_expression of
|
hcp1
|
shown in qRT-PCR approach
|
| 28376 |
lasR
|
|
decreases_expression of
|
hcp1
|
shown in qRT-PCR approach
|
|
19497948
|
Pseudomonas aeruginosa diseases
|
|
3,206
|
| 29543 |
rsmA
|
|
decreases_expression of
|
T6SS-HSI-1 complex
|
|
|
22354680
|
Pseudomonas aeruginosa diseases
|
|
3,348
|
| 30751 |
LasR/I-3OC12-(HSL)-system
|
|
increases_expression of
|
T6SS-HSI-2 complex
|
|
| 30755 |
RhlR/I-C4-(HSL)-system
|
|
increases_expression of
|
T6SS-HSI-2 complex
|
|
| 30759 |
fur
|
|
affects_expression of
|
T6SS-HSI-2 complex
|
|
| 30764 |
P. aeruginosa infection
|
|
increases_activity of
|
T6SS-HSI-2
|
analysed by internalization of P. aeruginosa into HeLa cells
|
| 30765 |
T6SS-HSI-2
|
|
increases_activity of
|
phosphatidylinositol 3-kinase signaling
|
analysed by internalization of P. aeruginosa into Calu-3 cells
|
| 30835 |
T6SS-HSI-2
|
|
increases_activity of
|
protein kinase B signaling
|
analysed by internalization of P. aeruginosa into Calu-3 cells
|
|
22665491
|
Pseudomonas aeruginosa diseases
|
|
3,356
|
| 30781 |
T6SS-HSI-1
|
|
increases_transport of
|
tse2
|
into bacterial recipient
|
| 30783 |
tse2
|
|
decreases_activity of
|
cell proliferation
|
in bacterial recipient
|
| 30784 |
tsi2
|
|
decreases_activity of
|
tse2
|
in bacterial recipient
|
| 30785 |
tsi2
|
|
increases_activity of
|
cell proliferation
|
in bacterial recipient
|
| 30786 |
tsi2
|
|
interacts (colocalizes) with
|
tse2
|
analysed in an E. coli bacterial two-hybrid (B2H) assay
|
| 30787 |
tsi2
|
NOT |
affects transport of
|
tse2
|
|
| 30790 |
tsi2
|
|
interacts (colocalizes) with
|
tsi2
|
|
|
22511866
|
Pseudomonas aeruginosa diseases
|
|
3,586
|
| 33575 |
tagJ1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 33576 |
tssB1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 33577 |
tagJ1
|
|
interacts (colocalizes) with
|
tssB1
|
shown in a bacterial two-hybrid (BTH) system and copurification experiments
|
| 33578 |
tssB1
|
|
increases_transport of
|
vgrG1a
|
analysed in a PAK-delta-rets background
|
| 33579 |
tssB1
|
|
increases_transport of
|
vgrG1c
|
analysed in a PAK-delta-rets background
|
| 33580 |
tssB1
|
|
increases_transport of
|
hcp1
|
analysed in a PAK-delta-rets background
|
| 33581 |
tssB1
|
|
increases_transport of
|
tse3
|
analysed in a PAK-delta-rets background
|
| 33582 |
tagJ1
|
NOT |
increases_transport of
|
vgrG1a
|
analysed in a PAK-delta-rets background
|
| 33583 |
tagJ1
|
NOT |
increases_transport of
|
vgrG1c
|
analysed in a PAK-delta-rets background
|
| 33584 |
tagJ1
|
NOT |
increases_transport of
|
hcp1
|
analysed in a PAK-delta-rets background
|
| 33585 |
tagJ1
|
NOT |
increases_transport of
|
tse3
|
analysed in a PAK-delta-rets background
|
| 33586 |
hsiB2
|
|
is_part_of
|
T6SS-HSI-2 complex
|
|
| 33587 |
hsiB3
|
|
is_part_of
|
T6SS-HSI-3, right operon
|
|
| 33588 |
tagJ1
|
NOT |
interacts (colocalizes) with
|
hsiB2
|
|
| 33591 |
tssB1
|
|
increases_activity of
|
T6SS-HSI-1
|
|
|
22906320
|
Pseudomonas aeruginosa diseases
|
|
3,590
|
| 33606 |
tssE1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 33608 |
hsiF2
|
|
is_part_of
|
T6SS-HSI-2 complex
|
|
| 33609 |
hsiF3
|
|
is_part_of
|
T6SS-HSI-3, right operon
|
|
| 33613 |
tssE1
|
|
increases_transport of
|
vgrG1a
|
analysed in a PAK-delta-rets background
|
| 33615 |
tssE1
|
|
increases_transport of
|
vgrG1c
|
analysed in a PAK-delta-rets background
|
| 33616 |
tssE1
|
NOT |
increases_transport of
|
vgrG1b
|
analysed in a PAK-delta-rets background
|
| 33617 |
tssE1
|
|
increases_transport of
|
hcp1
|
analysed in a PAK-delta-rets background
|
| 33625 |
tssE1
|
|
is localized in
|
cytoplasm
|
analysed in a PAK-delta-rets background
|
|
21873404
|
Pseudomonas aeruginosa diseases
|
|
3,638
|
| 34469 |
clpV1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 34475 |
tssB1
|
|
is_part_of
|
T6SS-HSI-1 complex
|
|
| 34477 |
tssB1
|
|
increases_activity of
|
T6SS-HSI-1
|
|
| 34480 |
T6SS-HSI-1
|
|
affects_folding of
|
T6SS-HSI-1 complex
|
between sister cells of bacteria
|
|
22767897
|
Pseudomonas aeruginosa diseases
|
|
3,874
|
| 39006 |
T6SS-HSI-1
|
|
increases_activity of
|
killing of other bacteria
|
in a coculture of P. aeruginosa PAO1 (T6SS+)/B. thailandensis or P. aeruginosa PAO1 (T6SS+)/S. typhimurium, shown by time-lapse fluorescence microscopy
|
| 39036 |
tse1
|
|
increases_activity of
|
killing of other bacteria
|
in a coculture of P. aeruginosa PAO1 (T6SS+)/B. thailandensis or P. aeruginosa PAO1 (T6SS+)/S. typhimurium, shown by time-lapse fluorescence microscopy
|
| 39058 |
T6SS-HSI-1
|
|
increases_activity of
|
T6SS dueling
|
in a coculture of P. aeruginosa PAO1 (T6SS+)/B. thailandensis or P. aeruginosa PAO1 (T6SS+)/S. typhimurium, shown by time-lapse fluorescence microscopy
|
| 39066 |
T6SS dueling
|
|
increases_activity of
|
killing of other bacteria
|
between neighboring cells
|
|
23150540
|
Pseudomonas aeruginosa diseases
|
|
3,878
|
| 39068 |
T6SS-HSI-1
|
|
increases_activity of
|
killing of other bacteria
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39069 |
T6SS-HSI-1
|
|
increases_activity of
|
T6SS dueling
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39082 |
T6SS-HSI-1
|
|
increases_activity of
|
membrane destabilization
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39095 |
T6SS-HSI-1
|
|
increases_transport of
|
tse1
|
into V. cholerae
|
| 39097 |
tse1
|
NOT |
increases_activity of
|
T6SS dueling
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39103 |
tse2
|
NOT |
increases_activity of
|
T6SS dueling
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39105 |
tse3
|
NOT |
increases_activity of
|
T6SS dueling
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39106 |
tse1
|
NOT |
increases_activity of
|
killing of other bacteria
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39107 |
tse2
|
NOT |
increases_activity of
|
killing of other bacteria
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39108 |
tse3
|
NOT |
increases_activity of
|
killing of other bacteria
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39111 |
ppkA
|
|
increases_activity of
|
T6SS-HSI-1
|
|
| 39112 |
pppA
|
|
decreases_activity of
|
T6SS-HSI-1
|
|
| 39113 |
tagT1
|
|
increases_activity of
|
T6SS dueling
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39140 |
ppkA
|
|
affects_activity of
|
T6SS dueling
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39142 |
pppA
|
|
affects_activity of
|
T6SS dueling
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39143 |
tagQ1
|
|
increases_activity of
|
T6SS dueling
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39144 |
tagR1
|
|
increases_activity of
|
T6SS dueling
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39146 |
tagS1
|
|
increases_activity of
|
T6SS dueling
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39148 |
T6SS dueling
|
|
increases_activity of
|
killing of other bacteria
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), or P.aeruginosa/A. baylyi, shown by time-lapse fluorescence microscopy
|
| 39154 |
tse1
|
|
decreases_quantity of
|
peptidoglycan, exogenous
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), shown by time-lapse fluorescence microscopy
|
| 39155 |
membrane destabilization
|
|
decreases_quantity of
|
peptidoglycan, exogenous
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), shown by time-lapse fluorescence microscopy
|
| 39158 |
tse1
|
|
increases_activity of
|
membrane destabilization
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/V. cholerae 2740-80 (T6SS+), shown by time-lapse fluorescence microscopy
|
| 39161 |
T6SS-HSI-1
|
NOT |
increases_activity of
|
T6SS dueling
|
in a coculture of P.aeruginosa PAO1 (T6SS+)/E. coli (T6SS-)
|
|
23415234
|
Pseudomonas aeruginosa diseases
|
|
3,882
|
| 39130 |
tagQ1
|
|
increases_activity of
|
ppkA
|
|
| 39136 |
tagR1
|
|
increases_activity of
|
ppkA
|
|
| 39137 |
tagS1
|
|
increases_activity of
|
ppkA
|
|
| 39138 |
tagT1
|
|
increases_activity of
|
ppkA
|
|
|
23415234
|
Pseudomonas aeruginosa diseases
|
|
3,886
|
| 39203 |
tagQ1
|
|
affects_activity of
|
phosphorylation-dependent type VI secretion activation
|
|
| 39208 |
tagS1
|
|
affects_activity of
|
phosphorylation-dependent type VI secretion activation
|
|
| 39209 |
tagT1
|
|
affects_activity of
|
phosphorylation-dependent type VI secretion activation
|
|
| 39210 |
tagT1
|
|
interacts (colocalizes) with
|
tagS1
|
in the inner membrane
|
| 39211 |
tagQ1
|
|
is localized in
|
bacterial outer membrane
|
|
| 39212 |
tagT-tagS complex
|
NOT |
affects transport of
|
tagQ1
|
to the outer membrane
|
| 39213 |
tagT-tagS complex
|
NOT |
affects transport of
|
tssJ1
|
to the outer membrane
|
| 39214 |
tagT1
|
|
is_part_of
|
tagT-tagS complex
|
|
| 39215 |
tagS1
|
|
is_part_of
|
tagT-tagS complex
|
|
| 39217 |
tagQ1
|
|
affects transport of
|
tagR1
|
to the outer membrane
|
| 39218 |
tssJ1
|
|
is localized in
|
bacterial outer membrane
|
|
|
22765374
|
Pseudomonas aeruginosa diseases
|
|
3,949
|
| 40086 |
tle5
|
|
increases_quantity of
|
Choline
|
analysed in an enzyme assay in lipid vesicles
|
| 40088 |
tle5
|
|
decreases_quantity of
|
Phosphatidylcholine
|
analysed in an enzyme assay in lipid vesicles
|
| 40089 |
tle5
|
|
interacts (colocalizes) with
|
tli5
|
|
| 40090 |
T6SS-HSI-2
|
|
increases_transport of
|
tle5
|
|
| 40091 |
tli5
|
|
decreases_activity of
|
tle5
|
|
| 40092 |
tle5
|
|
increases_quantity of
|
Phosphatidate
|
|
| 40093 |
tle5
|
|
decreases_quantity of
|
Phosphatidylethanolamine
|
|
| 40094 |
tle5
|
|
increases_activity of
|
killing of other bacteria
|
|
| 40095 |
tle5
|
|
increases_activity of
|
membrane destabilization
|
|
| 40096 |
T6SS-HSI-2
|
|
increases_activity of
|
T6SS dueling
|
|
| 45380 |
T6SS-HSI-2
|
|
increases_activity of
|
killing of other bacteria
|
|
|
23552891
|
Pseudomonas aeruginosa diseases
|
|
3,985
|
| 40561 |
tssB1
|
|
interacts (colocalizes) with
|
tssC1
|
if co-expressed in E. coli cells and shown in a bacterial two-hybrid system
|
| 40562 |
hsiB2
|
|
interacts (colocalizes) with
|
hsiC2
|
shown in a bacterial two-hybrid system
|
| 40563 |
hsiB2
|
|
is_part_of
|
T6SS-HSI-2 complex
|
|
| 40564 |
hsiC2
|
|
is_part_of
|
T6SS-HSI-2 complex
|
|
| 40565 |
hsiB2
|
NOT |
interacts (colocalizes) with
|
tssC1
|
shown in a bacterial two-hybrid system
|
| 40566 |
tssB1
|
NOT |
interacts (colocalizes) with
|
hsiC2
|
shown in a bacterial two-hybrid system
|
| 40567 |
tssC1
|
|
increases_activity of
|
T6SS-HSI-1
|
|
|
23341461
|
Pseudomonas aeruginosa diseases
|
|
4,252
|
| 43368 |
mucus layer
|
|
increases_expression of
|
T6SS-HSI-1 complex
|
in mucoid CF isolate PA2192
|
| 43369 |
mucus layer
|
|
increases_expression of
|
tssA1
|
in mucoid CF isolate PA2192
|
| 43370 |
mucus layer
|
|
increases_expression of
|
tagQ1
|
in mucoid CF isolate PA2192
|
| 43371 |
mucus layer
|
|
increases_expression of
|
tssB1
|
in mucoid CF isolate PA2192
|
| 43372 |
mucus layer
|
|
increases_expression of
|
hcp1
|
in mucoid CF isolate PA2192
|
|
23143799
|
Pseudomonas aeruginosa diseases
|
|
4,548
|
| 45376 |
P. aeruginosa infection
|
|
increases_activity of
|
T6SS-HSI-2
|
as shown in a C. elegans killing assay
|
| 45377 |
P. aeruginosa infection
|
|
increases_activity of
|
T6SS-HSI-3
|
as shown in a C. elegans killing assay
|
| 45378 |
clpV3
|
|
is_part_of
|
T6SS-HSI-3, right operon
|
|
|
24204589
|
Pseudomonas aeruginosa diseases
|
|
4,550
|
| 45381 |
sfa3
|
|
is_part_of
|
T6SS-HSI-3, left operon
|
|
| 45382 |
hsiA3
|
|
is_part_of
|
T6SS-HSI-3, left operon
|
|
| 45386 |
icmF3
|
|
is_part_of
|
T6SS-HSI-3, left operon
|
|
| 45387 |
dotU3
|
|
is_part_of
|
T6SS-HSI-3, left operon
|
|
| 45388 |
lip3
|
|
is_part_of
|
T6SS-HSI-3, left operon
|
|
| 45389 |
hsiB3
|
|
is_part_of
|
T6SS-HSI-3, right operon
|
|
| 45390 |
hsiC3
|
|
is_part_of
|
T6SS-HSI-3, right operon
|
|
| 45391 |
hcp3
|
|
is_part_of
|
T6SS-HSI-3, right operon
|
|
| 45393 |
hsiF3
|
|
is_part_of
|
T6SS-HSI-3, right operon
|
|
| 45394 |
hsiG3
|
|
is_part_of
|
T6SS-HSI-3, right operon
|
|
| 45395 |
hsiH3
|
|
is_part_of
|
T6SS-HSI-3, right operon
|
|
| 45397 |
clpV3
|
|
is_part_of
|
T6SS-HSI-3, right operon
|
|
| 45398 |
vgrG3
|
|
is_part_of
|
T6SS-HSI-3, right operon
|
|
| 45400 |
T6SS-HSI-3, right operon
|
|
is_part_of
|
T6SS-HSI-3 complex
|
|
| 45401 |
T6SS-HSI-3, left operon
|
|
is_part_of
|
T6SS-HSI-3 complex
|
|
| 45402 |
LasR/I-3OC12-(HSL)-system
|
|
increases_expression of
|
T6SS-HSI-3, left operon
|
|
| 45404 |
LasR/I-3OC12-(HSL)-system
|
|
increases_expression of
|
T6SS-HSI-3, right operon
|
|
| 45405 |
RhlR/I-C4-(HSL)-system
|
|
increases_expression of
|
T6SS-HSI-3, left operon
|
|
| 45406 |
RhlR/I-C4-(HSL)-system
|
|
increases_expression of
|
T6SS-HSI-3, right operon
|
|
| 45407 |
LasR/I-3OC12-(HSL)-system
|
|
increases_expression of
|
T6SS-HSI-2 complex
|
|
| 45408 |
RhlR/I-C4-(HSL)-system
|
|
increases_expression of
|
T6SS-HSI-2 complex
|
|
| 45412 |
rpoN
|
|
increases_expression of
|
T6SS-HSI-3, left operon
|
|
| 45413 |
rpoN
|
|
decreases_expression of
|
T6SS-HSI-3, right operon
|
|
| 45414 |
rpoN
|
|
decreases_expression of
|
T6SS-HSI-2 complex
|
|
| 45415 |
sfa2
|
|
decreases_expression of
|
T6SS-HSI-2 complex
|
|
| 45416 |
sfa2
|
|
increases_activity of
|
rpoN
|
|
| 45506 |
sfa2
|
NOT |
affects_expression of
|
T6SS-HSI-3, left operon
|
|
| 45509 |
sfa2
|
NOT |
affects_expression of
|
T6SS-HSI-3, right operon
|
|
|
24204589
|
Pseudomonas aeruginosa diseases
|
HoPaCI