| 12722831 |
Ishizawa T et al.:
Colocalization of tau and alpha-synuclein epitopes in Lewy bodies.
J. Neuropathol. Exp. Neurol.
2003
62: 389-397
|
| 9930729 |
Lesort M et al.:
Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase.
J. Neurochem.
1999
72: 576-584
|
| 8250835 |
Sutherland C et al.:
Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling.
Biochem. J.
1993
296: 15-19
|
| 8382613 |
Hughes K et al.:
Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation.
EMBO J.
1993
12: 803-808
|
| 9685326 |
Pap M et al.:
Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.
J. Biol. Chem.
1998
273
|
| 8978681 |
Alessi DR et al.:
Mechanism of activation of protein kinase B by insulin and IGF-1.
EMBO J.
1996
15: 6541-6551
|
| 8978681 |
Alessi DR et al.:
Mechanism of activation of protein kinase B by insulin and IGF-1
EMBO J.
1996
15: 6541-6551
|
| 8978681 |
Alessi DR et al.:
Mechanism of activation of protein kinase B by insulin and IGF-1
EMBO J.
1996
15: 6541-6551
|
| 11527574 |
Grimes CA et al.:
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
Prog. Neurobiol.
2001
65: 391-426
|
| 9468292 |
Welsh GI et al.:
Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin.
FEBS Lett.
1998
421: 125-130
|
| 18852354 |
Schaffer BA et al.:
Association of GSK3B with Alzheimer disease and frontotemporal dementia
Arch. Neurol.
2008
65: 1368-1374
|
| 1899151 |
Moore CK et al.:
Cardiac allograft cellular rejection during OKT3 prophylaxis in the absence of sensitization
Transplant. Proc.
1991
23: 1055-1058
|
| 18932008 |
Mendes CT et al.:
Lithium reduces Gsk3b mRNA levels: implications for Alzheimer Disease
Eur Arch Psychiatry Clin Neurosci
2009
259: 16-22
|
| 16944319 |
Verdile G et al.:
The role of presenilin and its interacting proteins in the biogenesis of Alzheimers beta amyloid.
Neurochem. Res.
2007
32: 609-623
|
| 16641999 |
Chen F et al.:
TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity
Nature
2006
440: 1208-1212
|
| 16641999 |
Chen F et al.:
TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity.
Nature
2006
440: 1208-1212
|
| 19779148 |
Kang JE et al.:
Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle.
Science
2009
326: 1005-1007
|
| 10993067 |
Yu G et al.:
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing
Nature
2000
407: 48-54
|
| 10993067 |
Yu G et al.:
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing.
Nature
2000
407: 48-54
|
| 12660785 |
Takasugi N et al.:
The role of presenilin cofactors in the gamma-secretase complex.
Nature
2003
422: 438-441
|
| 12032140 |
Yang DS et al.:
Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins.
J. Biol. Chem.
2002
277
|
| 12032140 |
Yang DS et al.:
Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins
J. Biol. Chem.
2002
277
|
| 12044882 |
Tomita T et al.:
Complex N-glycosylated form of nicastrin is stabilized and selectively bound to presenilin fragments.
FEBS Lett.
2002
520: 117-121
|
| 12048259 |
Edbauer D et al.:
Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation.
Proc. Natl. Acad. Sci. U.S.A.
2002
99: 8666-8671
|
| 14981233 |
Schubert M et al.:
Role for neuronal insulin resistance in neurodegenerative diseases
Proc. Natl. Acad. Sci. U.S.A.
2004
101: 3100-3105
|
| 19144826 |
Lee HK et al.:
The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid.
Mol. Biol. Cell
2009
20: 1533-1544
|
| 19144826 |
Lee HK et al.:
The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid
Mol. Biol. Cell
2009
20: 1533-1544
|
| 19712582 |
de la Monte SM et al.:
Insulin resistance and Alzheimers disease
BMB Rep
2009
42: 475-481
|
| 12904469 |
Schubert M et al.:
Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation
J. Neurosci.
2003
23: 7084-7092
|
| 1904481 |
Perry G et al.:
Neuropil threads of Alzheimers disease show a marked alteration of the normal cytoskeleton
J. Neurosci.
1991
11: 1748-1755
|
| 8592647 |
Takashima A et al.:
Amyloid beta peptide induces cytoplasmic accumulation of amyloid protein precursor via tau protein kinase I/glycogen synthase kinase-3 beta in rat hippocampal neurons.
Neurosci. Lett.
1995
198: 83-86
|
| 15094077 |
Watson GS et al.:
Modulation of memory by insulin and glucose: neuropsychological observations in Alzheimers disease
Eur. J. Pharmacol.
2004
490: 97-113
|
| 10672254 |
Hoyer S et al.:
Inhibition of the neuronal insulin receptor causes Alzheimer-like disturbances in oxidative/energy brain metabolism and in behavior in adult rats
Ann. N. Y. Acad. Sci.
1999
893: 301-303
|
| 11943765 |
Leem JY et al.:
Presenilin 1 is required for maturation and cell surface accumulation of nicastrin.
J. Biol. Chem.
2002
277
|
| 11146649 |
Sato N et al.:
Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.
Nat. Cell Biol.
2000
2: 863-870
|
| 12846562 |
Beher D et al.:
In vitro characterization of the presenilin-dependent gamma-secretase complex using a novel affinity ligand
Biochemistry
2003
42: 8133-8142
|
| 15189355 |
Shirotani K et al.:
Immature nicastrin stabilizes APH-1 independent of PEN-2 and presenilin: identification of nicastrin mutants that selectively interact with APH-1.
J. Neurochem.
2004
89: 1520-1527
|
| 15676027 |
Uchida Y et al.:
Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimers disease.
Genes Cells
2005
10: 165-179
|
| 19940183 |
Rudrabhatla P et al.:
Peptidyl-prolyl isomerase 1 regulates protein phosphatase 2A-mediated topographic phosphorylation of neurofilament proteins.
J. Neurosci.
2009
29
|
| 18635547 |
Rudrabhatla P et al.:
Pin1-dependent prolyl isomerization modulates the stress-induced phosphorylation of high molecular weight neurofilament protein.
J. Biol. Chem.
2008
283
|
| 18635547 |
Rudrabhatla P et al.:
Pin1-dependent prolyl isomerization modulates the stress-induced phosphorylation of high molecular weight neurofilament protein
J. Biol. Chem.
2008
283
|
| 19661622 |
Popp J et al.:
Homocysteine metabolism and cerebrospinal fluid markers for Alzheimers disease.
J. Alzheimers Dis.
2009
18: 819-828
|
| 19661623 |
Goni-Oliver P et al.:
Memantine inhibits calpain-mediated truncation of GSK-3 induced by NMDA: implications in Alzheimers disease
J. Alzheimers Dis.
2009
18: 843-848
|
| 17626162 |
Kesavapany S et al.:
Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons
Mol. Biol. Cell
2007
18: 3645-3655
|
| 17626162 |
Kesavapany S et al.:
Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons.
Mol. Biol. Cell
2007
18: 3645-3655
|
| 10672251 |
Frolich L et al.:
A disturbance in the neuronal insulin receptor signal transduction in sporadic Alzheimers disease.
Ann. N. Y. Acad. Sci.
1999
893: 290-293
|
| 10231383 |
Li BS et al.:
Activation of mitogen-activated protein kinases (Erk1 and Erk2) cascade results in phosphorylation of NF-M tail domains in transfected NIH 3T3 cells.
Eur. J. Biochem.
1999
262: 211-217
|
| 10670439 |
Boyt AA et al.:
The effect of insulin and glucose on the plasma concentration of Alzheimers amyloid precursor protein.
Neuroscience
2000
95: 727-734
|
| 17298085 |
Zhou S et al.:
Regulation of gamma-secretase activity in Alzheimers disease.
Biochemistry
2007
46: 2553-2563
|
| 12761548 |
Phiel CJ et al.:
GSK-3alpha regulates production of Alzheimers disease amyloid-beta peptides
Nature
2003
423: 435-439
|
| 19090986 |
Cashman JR et al.:
Immune defects in Alzheimers disease: new medications development.
BMC Neurosci
2008
9: S13
|
| 10341227 |
Kang DE et al.:
Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimers disease-linked PS1 mutants in the beta-catenin-signaling pathway
J. Neurosci.
1999
19: 4229-4237
|
| 12297048 |
Kang DE et al.:
Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis
Cell
2002
110: 751-762
|
| 11554609 |
Klunk WE et al.:
Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain.
Life Sci.
2001
69: 1471-1484
|
| 14651959 |
Ryder J et al.:
Divergent roles of GSK3 and CDK5 in APP processing
Biochem. Biophys. Res. Commun.
2003
312: 922-929
|
| 14651959 |
Ryder J et al.:
Divergent roles of GSK3 and CDK5 in APP processing.
Biochem. Biophys. Res. Commun.
2003
312: 922-929
|
| 18189321 |
Chen Q et al.:
Loss of presenilin function causes Alzheimers disease-like neurodegeneration in the mouse.
J. Neurosci. Res.
2008
86: 1615-1625
|
| 19337449 |
Gotz J et al.:
An update on the toxicity of Abeta in Alzheimers disease.
Neuropsychiatr Dis Treat
2008
4: 1033-1042
|
| 17708691 |
Crouch PJ et al.:
Mitochondria in aging and Alzheimers disease.
Rejuvenation Res
2007
10: 349-357
|
| 19268425 |
Celsi F et al.:
Mitochondria, calcium and cell death: a deadly triad in neurodegeneration
Biochim. Biophys. Acta
2009
1787: 335-344
|
| 9051814 |
Guo Q et al.:
Alzheimers PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid beta-peptide
Neuroreport
1996
8: 379-383
|
| 16394273 |
Lee SY et al.:
PS2 mutation increases neuronal cell vulnerability to neurotoxicants through activation of caspase-3 by enhancing of ryanodine receptor-mediated calcium release
FASEB J.
2006
20: 151-153
|
| 15659604 |
Crouch PJ et al.:
Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42
J. Neurosci.
2005
25: 672-679
|
| 15170327 |
Su Y et al.:
Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing
Biochemistry
2004
43: 6899-6908
|
| 15170327 |
Su Y et al.:
Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing
Biochemistry
2004
43: 6899-6908
|
| 16014628 |
Feyt C et al.:
Lithium chloride increases the production of amyloid-beta peptide independently from its inhibition of glycogen synthase kinase 3.
J. Biol. Chem.
2005
280
|
| 15485501 |
Good PF et al.:
A role for semaphorin 3A signaling in the degeneration of hippocampal neurons during Alzheimers disease.
J. Neurochem.
2004
91: 716-736
|
| 15634781 |
Ma G et al.:
APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development.
J. Neurosci.
2005
25: 192-198
|
| 19478559 |
Yoon EJ et al.:
Intracellular amyloid beta interacts with SOD1 and impairs the enzymatic activity of SOD1: implications for the pathogenesis of amyotrophic lateral sclerosis
Exp. Mol. Med.
2009
41: 611-617
|
| 15466863 |
Cole AR et al.:
GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons.
J. Biol. Chem.
2004
279
|
| 15466863 |
Cole AR et al.:
GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons
J. Biol. Chem.
2004
279
|
| 19793966 |
Jinwal UK et al.:
Chemical manipulation of hsp70 ATPase activity regulates tau stability
J. Neurosci.
2009
29
|
| 19449461 |
Koren J 3rd et al.:
Chaperone signalling complexes in Alzheimers disease
J. Cell. Mol. Med.
2009
13: 619-630
|
| 16724068 |
Uehara T et al.:
S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration
Nature
2006
441: 513-517
|
| 16724068 |
Uehara T et al.:
S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration
Nature
2006
441: 513-517
|
| 16724068 |
Uehara T et al.:
S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration.
Nature
2006
441: 513-517
|
| 12522269 |
Dou F et al.:
Chaperones increase association of tau protein with microtubules.
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 721-726
|
| 12522269 |
Dou F et al.:
Chaperones increase association of tau protein with microtubules
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 721-726
|
| 14962978 |
Petrucelli L et al.:
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
Hum. Mol. Genet.
2004
13: 703-714
|
| 18061943 |
Bjorkdahl C et al.:
Small heat shock proteins Hsp27 or alphaB-crystallin and the protein components of neurofibrillary tangles: tau and neurofilaments.
J. Neurosci. Res.
2008
86: 1343-1352
|
| 18061943 |
Bjorkdahl C et al.:
Small heat shock proteins Hsp27 or alphaB-crystallin and the protein components of neurofibrillary tangles: tau and neurofilaments
J. Neurosci. Res.
2008
86: 1343-1352
|
| 19946466 |
Bonda DJ et al.:
Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease
Aging (Albany NY)
2009
1: 382-388
|
| 20237268 |
Biswas SC et al.:
Sertad1 plays an essential role in developmental and pathological neuron death
J. Neurosci.
2010
30: 3973-3982
|
| 19647374 |
Bajic VP et al.:
The X-chromosome instability phenotype in Alzheimers disease: a clinical sign of accelerating aging? }, authors { names std { { name ml Bajic VP, affil str Institute of Biomedical Research, Galenika ad, 11000 Belgrade, Serbia. vladanbajic@yahoo.com }, { name ml Spremo-Potparevic B }, { name ml Zivkovic L }, { name ml Bonda DJ }, { name ml Siedlak SL }, { name ml Casadesus G }, { name ml Lee HG }, { name ml Smith MA } } }, from journal { title { iso-jta Med. Hypotheses, ml-jta Med Hypotheses, issn 1532-2777, name Medical hypotheses }, imp { date std { year 2009, month 12 }, volume 73, issue 6, pages 917-920, language eng, pubstatus ppublish, history { { pubstatus received, date std { year 2009, month 6, day 23 } }, { pubstatus accepted, date std { year 2009, month 6, day 24 } }, { pubstatus aheadofprint, date std { year 2009, month 7, day 31 } }, { pubstatus other, date std { year 2009, month 8, day 4, hour 9, minute 0 } }, { pubstatus pubmed, date std { year 2009, month 8, day 4, hour 9, minute 0 } }, { pubstatus medline, date std { year 2010, month 3, day 2, hour 6, minute 0 } } } } }, ids { pii S0306-9877(09)00478-2, doi 10.1016/j.mehy.2009.06.046, pubmed 19647374, other { db pmc, tag str PMC2787990 }, other { db mid, tag str NIHMS136441 }, other { db ELocationID doi, tag str 10.1016/j.mehy.2009.06.046 } } }, abstract Premature centromere division, or premature centromere separation (PCS), occurs when chromatid separation is dysfunctional, occurring earlier than usual during the interphase stage of mitosis. This phenomenon, seen in Roberts syndrome and various cancers, has also been documented in peripheral as well as neuronal cells of Alzheimers disease (AD). In the latter instances, fluorescent in situ hybridization (FISH), applied to the centromere region of the X-chromosome in interphase nuclei of lymphocytes from peripheral blood in AD patients, demonstrated premature chromosomal separation before mitotic metaphase directly after completion of DNA replication in G(2) phase of the cell cycle. Furthermore, and perhaps unexpectedly given the presumptive post-mitotic status of terminally differentiated neurons, neurons in AD patients also showed significantly increased levels of PCS of the X-chromosome. Taken together with other phenomena such as cell cycle re-activation and ectopic re-expression of cyclins and cyclin dependent proteins, we propose that AD is an oncogenic phenotype leading to accelerated aging of the affected brain
Med. Hypotheses
2009
73: 917-920
|
| 12624792 |
Pei JJ et al.:
Role of protein kinase B in Alzheimers neurofibrillary pathology.
Acta Neuropathol.
2003
105: 381-392
|
| 17276679 |
Ansar S et al.:
A non-toxic Hsp90 inhibitor protects neurons from Abeta-induced toxicity.
Bioorg. Med. Chem. Lett.
2007
17: 1984-1990
|
| 14963027 |
Shimura H et al.:
Binding of tau to heat shock protein 27 leads to decreased concentration of hyperphosphorylated tau and enhanced cell survival.
J. Biol. Chem.
2004
279
|
| 15132984 |
Nemes Z et al.:
Cross-linking of ubiquitin, HSP27, parkin, and alpha-synuclein by gamma-glutamyl-epsilon-lysine bonds in Alzheimers neurofibrillary tangles.
FASEB J.
2004
18: 1135-1137
|
| 15615647 |
Kosik KS et al.:
Phosphorylated tau and the neurodegenerative foldopathies.
Biochim. Biophys. Acta
2005
1739: 298-310
|
| 14612456 |
Shimura H et al.:
CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival
J. Biol. Chem.
2004
279: 4869-4876
|
| 12888622 |
Gamblin TC et al.:
Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimers disease
Proc. Natl. Acad. Sci. U.S.A.
2003
100
|
| 20357768 |
de Calignon A et al.:
Caspase activation precedes and leads to tangles.
Nature
2010
464: 1201-1204
|
| 19191039 |
Sun AY et al.:
Botanical phenolics and brain health
Neuromolecular Med.
2008
10: 259-274
|
| 12793519 |
Joseph JA et al.:
Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model.
Nutr Neurosci
2003
6: 153-162
|
| 16177050 |
Rezai-Zadeh K et al.:
Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice
J. Neurosci.
2005
25: 8807-8814
|
| 16177050 |
Rezai-Zadeh K et al.:
Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice
J. Neurosci.
2005
25: 8807-8814
|
| 16624814 |
Obregon DF et al.:
ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein
J. Biol. Chem.
2006
281
|
| 15579468 |
Kanekura K et al.:
A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death
J. Biol. Chem.
2005
280: 4532-4543
|
| 16636099 |
Chen F et al.:
Reductions in levels of the Alzheimers amyloid beta peptide after oral administration of ginsenosides
FASEB J.
2006
20: 1269-1271
|
| 16636099 |
Chen F et al.:
Reductions in levels of the Alzheimers amyloid beta peptide after oral administration of ginsenosides
FASEB J.
2006
20: 1269-1271
|
| 15277073 |
Chauhan NB et al.:
Anti-amyloidogenic effect of Allium sativum in Alzheimers transgenic model Tg2576
J Herb Pharmacother
2003
3: 95-107
|
| 20385830 |
Han W et al.:
Linking type 2 diabetes and Alzheimers disease
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 6557-6558
|
| 20231468 |
Takeda S et al.:
Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 7036-7041
|
| 11880515 |
Westerman MA et al.:
The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimers disease
J. Neurosci.
2002
22: 1858-1867
|
| 19242462 |
Cisse M et al.:
Alzheimers disease: A prion protein connection.
Nature
2009
457: 1090-1091
|
| 19829367 |
Mucke L et al.:
Neuroscience: Alzheimers disease
Nature
2009
461: 895-897
|
| 17082448 |
Roberson ED et al.:
100 years and counting: prospects for defeating Alzheimers disease.
Science
2006
314: 781-784
|
| 16842945 |
Chauhan NB et al.:
Effect of aged garlic extract on APP processing and tau phosphorylation in Alzheimers transgenic model Tg2576
J Ethnopharmacol
2006
108: 385-394
|
| 17380553 |
Chauhan NB et al.:
Amelioration of early cognitive deficits by aged garlic extract in Alzheimers transgenic mice
Phytother Res
2007
21: 629-640
|
| 17380553 |
Chauhan NB et al.:
Amelioration of early cognitive deficits by aged garlic extract in Alzheimers transgenic mice.
Phytother Res
2007
21: 629-640
|
| 14637120 |
Stackman RW et al.:
Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimers disease by chronic Ginkgo biloba treatment
Exp. Neurol.
2003
184: 510-520
|
| 17086105 |
Garcia-Alloza M et al.:
Plaque-derived oxidative stress mediates distorted neurite trajectories in the Alzheimer mouse model
J. Neuropathol. Exp. Neurol.
2006
65: 1082-1089
|
| 15010693 |
Tohda C et al.:
Abeta(25-35)-induced memory impairment, axonal atrophy, and synaptic loss are ameliorated by M1, A metabolite of protopanaxadiol-type saponins.
Neuropsychopharmacology
2004
29: 860-868
|
| 17010630 |
Hartman RE et al.:
Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimers disease
Neurobiol. Dis.
2006
24: 506-515
|
| 19104446 |
Julien C et al.:
Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease.
J. Neuropathol. Exp. Neurol.
2009
68: 48-58
|
| 19548013 |
Tong Y et al.:
COL25A1 triggers and promotes Alzheimers disease-like pathology in vivo
Neurogenetics
2010
11: 41-52
|
| 20126630 |
Frykman S et al.:
Synaptic and endosomal localization of active gamma-secretase in rat brain.
PLoS ONE
2010
5: E8948
|
| 16183991 |
Chen J et al.:
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling
J. Biol. Chem.
2005
280
|
| 20061625 |
Huesa G et al.:
Altered distribution of RhoA in Alzheimers disease and AbetaPP overexpressing mice
J. Alzheimers Dis.
2010
19: 37-56
|
| 12603837 |
Siman R et al.:
Localization of presenilin-nicastrin complexes and gamma-secretase activity to the trans-Golgi network.
J. Neurochem.
2003
84: 1143-1153
|
| 19712581 |
Chung SH et al.:
Aberrant phosphorylation in the pathogenesis of Alzheimers disease
BMB Rep
2009
42: 467-474
|
| 10814741 |
Yasojima K et al.:
Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain.
Brain Res.
2000
865: 116-120
|
| 10412011 |
Yasojima K et al.:
Tangled areas of Alzheimer brain have upregulated levels of exon 10 containing tau mRNA.
Brain Res.
1999
831: 301-305
|
| 10924763 |
Schwab C et al.:
Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases
Neurobiol. Aging
2000
21: 503-510
|
| 15345711 |
Beglopoulos V et al.:
Reduced beta-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice.
J. Biol. Chem.
2004
279
|
| 19521544 |
Engmann O et al.:
Crosstalk between Cdk5 and GSK3beta: Implications for Alzheimers Disease.
Front Mol Neurosci
2009
2: 2
|
| 18691386 |
Sun KH et al.:
Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction
J. Neurochem.
2008
107: 265-278
|
| 9038181 |
Poon RY et al.:
Identification of functional domains in the neuronal Cdk5 activator protein.
J. Biol. Chem.
1997
272: 5703-5708
|
| 10604467 |
Patrick GN et al.:
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
Nature
1999
402: 615-622
|
| 19776350 |
Sun KH et al.:
Direct and indirect roles of cyclin-dependent kinase 5 as an upstream regulator in the c-Jun NH2-terminal kinase cascade: relevance to neurotoxic insults in Alzheimers disease.
Mol. Biol. Cell
2009
20: 4611-4619
|
| 20462385 |
Candore G et al.:
Inflammation, cytokines, immune response, apolipoprotein E, cholesterol, and oxidative stress in Alzheimer disease: therapeutic implications
Rejuvenation Res
2010
13: 301-313
|
| 11329064 |
Wyss-Coray T et al.:
TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice
Nat. Med.
2001
7: 612-618
|
| 18801740 |
Lukiw WJ et al.:
An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells
J. Biol. Chem.
2008
283
|
| 17905482 |
Letiembre M et al.:
Screening of innate immune receptors in neurodegenerative diseases: a similar pattern
Neurobiol. Aging
2009
30: 759-768
|
| 11749806 |
Zeng HH et al.:
Antioxidant properties of phenolic diterpenes from Rosmarinus officinalis
Acta Pharmacol. Sin.
2001
22: 1094-1098
|
| 2529544 |
Griffin WS et al.:
Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease
Proc. Natl. Acad. Sci. U.S.A.
1989
86: 7611-7615
|
| 15290893 |
Mrak RE et al.:
Trisomy 21 and the brain
J. Neuropathol. Exp. Neurol.
2004
63: 679-685
|
| 17360493 |
Flajolet M et al.:
Regulation of Alzheimers disease amyloid-beta formation by casein kinase I
Proc. Natl. Acad. Sci. U.S.A.
2007
104: 4159-4164
|
| 17094809 |
Wilkinson BL et al.:
The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimers disease
J Neuroinflammation
2006
3: 30
|
| 20552018 |
Schonrock N et al.:
Neuronal microRNA deregulation in response to Alzheimers disease amyloid-beta
PLoS ONE
2010
5
|
| 20552018 |
Schonrock N et al.:
Neuronal microRNA deregulation in response to Alzheimers disease amyloid-beta.
PLoS ONE
2010
5
|
| 19406203 |
Sethi P et al.:
Micro-RNA abundance and stability in human brain: specific alterations in Alzheimers disease temporal lobe neocortex
Neurosci. Lett.
2009
459: 100-104
|
| 20489155 |
Wang WX et al.:
miR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative disease.
Am. J. Pathol.
2010
177: 334-345
|
| 20126538 |
Nunez-Iglesias J et al.:
Joint genome-wide profiling of miRNA and mRNA expression in Alzheimers disease cortex reveals altered miRNA regulation
PLoS ONE
2010
5: E8898
|
| 20202123 |
Shioya M et al.:
Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3
Neuropathol. Appl. Neurobiol.
2010
36: 320-330
|
| 12787059 |
Castegna A et al.:
Proteomic identification of nitrated proteins in Alzheimers disease brain
J. Neurochem.
2003
85: 1394-1401
|
| 20472889 |
Arendt T et al.:
Selective cell death of hyperploid neurons in Alzheimers disease
Am. J. Pathol.
2010
177: 15-20
|
| 10867782 |
Hock C et al.:
Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas
Arch. Neurol.
2000
57: 846-851
|
| 15857398 |
Wang J et al.:
Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimers disease
J. Neurochem.
2005
93: 953-962
|
| 11733217 |
Butterfield DA et al.:
Evidence of oxidative damage in Alzheimers disease brain: central role for amyloid beta-peptide
Trends Mol Med
2001
7: 548-554
|
| 19654187 |
Wang Y et al.:
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing
Hum. Mol. Genet.
2009
18: 4153-4170
|
| 17485462 |
Ko MH et al.:
The sterol carrier protein SCP-x/pro-SCP-2 gene has transcriptional activity and regulates the Alzheimer disease gamma-secretase
J. Biol. Chem.
2007
282
|
| 20451302 |
Persengiev S et al.:
Genome-wide analysis of miRNA expression reveals a potential role for miR-144 in brain aging and spinocerebellar ataxia pathogenesis
Neurobiol. Aging
2011
32: 2316
|
| 20413881 |
Nelson PT et al.:
MiR-107 is reduced in Alzheimers disease brain neocortex: validation study
J. Alzheimers Dis.
2010
21: 75-79
|
| 20110602 |
Ciaramella A et al.:
Increased pro-inflammatory response by dendritic cells from patients with Alzheimers disease
J. Alzheimers Dis.
2010
19: 559-572
|
| 20134203 |
Morales I et al.:
Neuroimmunomodulation in the pathogenesis of Alzheimers disease
Neuroimmunomodulation
2010
17: 202-204
|
| 20122289 |
Zotova E et al.:
Inflammation in Alzheimers disease: relevance to pathogenesis and therapy
Alzheimers Res Ther
2010
2: 1
|
| 20696495 |
Wilkinson BL et al.:
Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimers disease
Neurobiol. Aging
2012
33: 197
|
| 20696495 |
Wilkinson BL et al.:
Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimers disease
Neurobiol. Aging
2012
33: 197
|
| 16645044 |
Wang R et al.:
Transcriptional regulation of APH-1A and increased gamma-secretase cleavage of APP and Notch by HIF-1 and hypoxia
FASEB J.
2006
20: 1275-1277
|
| 16645641 |
Xu Y et al.:
Intracellular domains of amyloid precursor-like protein 2 interact with CP2 transcription factor in the nucleus and induce glycogen synthase kinase-3beta expression
Cell Death Differ.
2007
14: 79-91
|
| 20594619 |
Robakis NK et al.:
Mechanisms of AD neurodegeneration may be independent of Abeta and its derivatives
Neurobiol. Aging
2011
32: 372-379
|
| 19641596 |
Zhang C et al.:
Presenilins are essential for regulating neurotransmitter release
Nature
2009
460: 632-636
|
| 18184791 |
Baki L et al.:
Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling
J. Neurosci.
2008
28: 483-490
|
| 19261853 |
Liu Z et al.:
Membrane-associated farnesylated UCH-L1 promotes alpha-synuclein neurotoxicity and is a therapeutic target for Parkinsons disease
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 4635-4640
|
| 20739979 |
Ledford H et al.:
Key Alzheimers findings questioned.
Nature
2010
466: 1031
|
| 20552043 |
Guglielmotto M et al.:
Oxidative stress mediates the pathogenic effect of different Alzheimers disease risk factors
Front Aging Neurosci
2010
2: 3
|
| 20817278 |
Duce JA et al.:
Iron-export ferroxidase activity of beta-amyloid precursor protein is inhibited by zinc in Alzheimers disease
Cell
2010
142: 857-867
|
| 19021541 |
Rogers JT et al.:
Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimers disease
Biochem. Soc. Trans.
2008
36: 1282-1287
|
| 20631161 |
Brewer GJ et al.:
Copper and ceruloplasmin abnormalities in Alzheimers disease
Am J Alzheimers Dis Other Demen
2010
25: 490-497
|
| 19166904 |
Cahill CM et al.:
Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases
Biochim. Biophys. Acta
2009
1790: 615-628
|
| 19631630 |
Yao L et al.:
Influence of the Pro12Ala polymorphism of PPAR-gamma on age at onset and sRAGE levels in Alzheimers disease
Brain Res.
2009
1291: 133-139
|
| 18400211 |
Cheng CY et al.:
Ferulic acid provides neuroprotection against oxidative stress-related apoptosis after cerebral ischemia/reperfusion injury by inhibiting ICAM-1 mRNA expression in rats
Brain Res.
2008
1209: 136-150
|
| 16205720 |
Gaeta A et al.:
The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy
Br. J. Pharmacol.
2005
146: 1041-1059
|
| 18687504 |
Jo DG et al.:
Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimers disease
Neurobiol. Aging
2010
31: 917-925
|
| 18687504 |
Jo DG et al.:
Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimers disease
Neurobiol. Aging
2010
31: 917-925
|
| 19965584 |
Vedin I et al.:
Reduced prostaglandin F2 alpha release from blood mononuclear leukocytes after oral supplementation of omega3 fatty acids: the OmegAD study
J. Lipid Res.
2010
51: 1179-1185
|
| 17014365 |
Andrews NC et al.:
Iron homeostasis
Annu. Rev. Physiol.
2007
69: 69-85
|
| 19225519 |
Nikolaev A et al.:
APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
Nature
2009
457: 981-989
|
| 19898775 |
Wang SM et al.:
Role of hepcidin in murine brain iron metabolism
Cell. Mol. Life Sci.
2010
67: 123-133
|
| 18585350 |
Dreses-Werringloer U et al.:
A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimers disease risk
Cell
2008
133: 1149-1161
|
| 20619502 |
Liu W et al.:
MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimers-associated pathogenesis in SAMP8 mice
Neurobiol. Aging
2012
33: 522-534
|
| 19090996 |
Block ML et al.:
NADPH oxidase as a therapeutic target in Alzheimers disease
BMC Neurosci
2008
9: S8
|
| 20442493 |
Young KJ et al.:
The mitochondrial secret(ase) of Alzheimers disease
J. Alzheimers Dis.
2010
20: S381-S400
|
| 16551656 |
Manczak M et al.:
Mitochondria are a direct site of A beta accumulation in Alzheimers disease neurons: implications for free radical generation and oxidative damage in disease progression
Hum. Mol. Genet.
2006
15: 1437-1449
|
| 20463396 |
Di Filippo M et al.:
Mitochondria and the link between neuroinflammation and neurodegeneration
J. Alzheimers Dis.
2010
20: S369-S379
|
| 20463408 |
Morais VA et al.:
Mitochondria dysfunction and neurodegenerative disorders: cause or consequence
J. Alzheimers Dis.
2010
20: S255-S263
|
| 15087549 |
Lustbader JW et al.:
ABAD directly links Abeta to mitochondrial toxicity in Alzheimers disease
Science
2004
304: 448-452
|
| 18757748 |
Hansson Petersen CA et al.:
The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae
Proc. Natl. Acad. Sci. U.S.A.
2008
105
|
| 15456764 |
Hansson CA et al.:
Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria
J. Biol. Chem.
2004
279
|
| 20655099 |
Ittner LM et al.:
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimers disease mouse models
Cell
2010
142: 387-397
|
| 20691893 |
Haass C et al.:
Fyn-tau-amyloid: a toxic triad
Cell
2010
142: 356-358
|
| 17088888 |
Lin MT et al.:
Alzheimers APP mangles mitochondria
Nat. Med.
2006
12: 1241-1243
|
| 12196559 |
Stein TD et al.:
Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways
J. Neurosci.
2002
22: 7380-7388
|
| 12196559 |
Stein TD et al.:
Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways
J. Neurosci.
2002
22: 7380-7388
|
| 14675736 |
Cardoso SM et al.:
Cytochrome c oxidase is decreased in Alzheimers disease platelets
Neurobiol. Aging
2004
25: 105-110
|
| 12270688 |
Casley CS et al.:
Beta-amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons
Neurobiol. Dis.
2002
10: 258-267
|
| 19605646 |
Wang X et al.:
Impaired balance of mitochondrial fission and fusion in Alzheimers disease
J. Neurosci.
2009
29: 9090-9103
|
| 15591653 |
Keil U et al.:
Elevated nitric oxide production mediates beta-amyloid-induced mitochondria failure
Pol J Pharmacol
2004
56: 631-634
|
| 20816785 |
Anekonda TS et al.:
L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimers disease.
Neurobiol. Dis.
2011
41: 62-70
|
| 21134458 |
Rozkalne A et al.:
Calcineurin inhibition with FK506 ameliorates dendritic spine density deficits in plaque-bearing Alzheimer model mice
Neurobiol. Dis.
2011
41: 650-654
|
| 20887789 |
Batlevi Y et al.:
Mitochondrial autophagy in neural function, neurodegenerative disease, neuron cell death, and aging
Neurobiol. Dis.
2011
43: 46-51
|
| 20888417 |
Massone S et al.:
17A, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease
Neurobiol. Dis.
2011
41: 308-317
|
| 21081164 |
Rohn TT et al.:
Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimers disease brain
Neurobiol. Dis.
2011
43: 68-78
|
| 20732422 |
Yamamoto A et al.:
The elimination of accumulated and aggregated proteins: a role for aggrephagy in neurodegeneration
Neurobiol. Dis.
2011
43: 17-28
|
| 12270682 |
Janciauskiene S et al.:
Interactions of A beta with endogenous anti-inflammatory agents: a basis for chronic neuroinflammation in Alzheimers disease
Neurobiol. Dis.
2002
10: 187-200
|
| 21270867 |
Ledford H et al.:
Alzheimers-disease probe nears approval.
Nature
2011
469: 458
|
| 20551690 |
Kaiser E et al.:
Cerebrospinal fluid concentrations of functionally important amino acids and metabolic compounds in patients with mild cognitive impairment and Alzheimers disease.
Neurodegener Dis
2010
7: 251-259
|
| 18037246 |
Padmashri R et al.:
Glutamate transporter blockade affects Ca(2+) responses in astrocytes.
Neuroscience
2008
151: 56-62
|
| 19897719 |
Rhein V et al.:
Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimers disease mice.
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 19035593 |
Frydman-Marom A et al.:
Cognitive-performance recovery of Alzheimers disease model mice by modulation of early soluble amyloidal assemblies.
Angew. Chem. Int. Ed. Engl.
2009
48: 1981-1986
|
| 20709030 |
Wang H et al.:
miR-106b aberrantly expressed in a double transgenic mouse model for Alzheimers disease targets TGF-beta type II receptor.
Brain Res.
2010
1357: 166-174
|
| 20937840 |
Cui JG et al.:
Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease
J. Biol. Chem.
2010
285
|
| 18838197 |
Vargas T et al.:
Abeta accumulation in choroid plexus is associated with mitochondrial-induced apoptosis
Neurobiol. Aging
2010
31: 1569-1581
|
| 21062284 |
Smith P et al.:
In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs.
J. Neurochem.
2011
116: 240-247
|
| 18434550 |
Hebert SS et al.:
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimers disease correlates with increased BACE1/beta-secretase expression
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 6415-6420
|
| 16599941 |
Wilhelmus MM et al.:
Specific association of small heat shock proteins with the pathological hallmarks of Alzheimers disease brains
Neuropathol. Appl. Neurobiol.
2006
32: 119-130
|
| 16611012 |
Gomez-Ramos A et al.:
Inhibition of GSK3 dependent tau phosphorylation by metals.
Curr Alzheimer Res
2006
3: 123-127
|
| 19795195 |
Pickrell AM et al.:
The role of cytochrome c oxidase deficiency in ROS and amyloid plaque formation.
J. Bioenerg. Biomembr.
2009
41: 453-456
|
| 19342591 |
Cho DH et al.:
S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury.
Science
2009
324: 102-105
|
| 19050078 |
Wang X et al.:
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins.
Proc. Natl. Acad. Sci. U.S.A.
2008
105
|
| 17715058 |
Fukui H et al.:
Cytochrome c oxidase deficiency in neurons decreases both oxidative stress and amyloid formation in a mouse model of Alzheimers disease
Proc. Natl. Acad. Sci. U.S.A.
2007
104
|
| 19091971 |
Liu Y et al.:
Amyloid pathology is associated with progressive monoaminergic neurodegeneration in a transgenic mouse model of Alzheimers disease.
J. Neurosci.
2008
28
|
| 19118186 |
Sato S et al.:
Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1
J. Neurosci.
2008
28
|
| 19118186 |
Sato S et al.:
Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1.
J. Neurosci.
2008
28
|
| 21208686 |
van Beek AH et al.:
Oscillations in cerebral blood flow and cortical oxygenation in Alzheimers disease
Neurobiol. Aging
2012
33: 428
|
| 19063999 |
Kennelly SP et al.:
Blood pressure and the risk for dementia: a double edged sword
Ageing Res. Rev.
2009
8: 61-70
|
| 18692159 |
Chung HY et al.:
Molecular inflammation: underpinnings of aging and age-related diseases.
Ageing Res. Rev.
2009
8: 18-30
|
| 18313368 |
Chung JH et al.:
Molecular mechanism of PPAR in the regulation of age-related inflammation
Ageing Res. Rev.
2008
7: 126-136
|
| 20170744 |
Vance JE et al.:
Formation and function of apolipoprotein E-containing lipoproteins in the nervous system
Biochim. Biophys. Acta
2010
1801: 806-818
|
| 20228251 |
Lee M et al.:
Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases.
FASEB J.
2010
24: 2533-2545
|
| 16025111 |
Snyder EM et al.:
Regulation of NMDA receptor trafficking by amyloid-beta.
Nat. Neurosci.
2005
8: 1051-1058
|
| 18813209 |
Chiba T et al.:
Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons.
Mol. Psychiatry
2009
14: 206-222
|
| 20889807 |
Geldmacher DS et al.:
Alzheimer disease prevention: focus on cardiovascular risk, not amyloid
Cleve Clin J Med
2010
77: 689-704
|
| 19076444 |
Gibson GE et al.:
Oxidant-induced changes in mitochondria and calcium dynamics in the pathophysiology of Alzheimers disease
Ann. N. Y. Acad. Sci.
2008
1147: 221-232
|
| 16472763 |
Clementi ME et al.:
Alzheimers amyloid beta-peptide (1-42) induces cell death in human neuroblastoma via bax/bcl-2 ratio increase: an intriguing role for methionine 35.
Biochem. Biophys. Res. Commun.
2006
342: 206-213
|
| 20933077 |
Zhang H et al.:
Puerarin protects Alzheimers disease neuronal cybrids from oxidant-stress induced apoptosis by inhibiting pro-death signaling pathways.
Exp. Gerontol.
2011
46: 30-37
|
| 21461981 |
Bajic VP et al.:
Mislocalization of CDK11/PITSLRE, a regulator of the G2/M phase of the cell cycle, in Alzheimer disease
Cell. Mol. Biol. Lett.
2011
16: 359-372
|
| 21421841 |
Jin M et al.:
Soluble amyloid {beta}-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration.
Proc. Natl. Acad. Sci. U.S.A.
2011
108: 5819-5824
|
| 21349442 |
Bonda DJ et al.:
The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations
Lancet Neurol
2011
10: 275-279
|
| 21121893 |
Monteiro JP et al.:
SIRT1 deacetylase activity and the maintenance of protein homeostasis in response to stress: an overview.
Protein Pept. Lett.
2011
18: 167-173
|
| 16751189 |
Qin W et al.:
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction.
J. Biol. Chem.
2006
281
|
| 17517621 |
De Ferrari GV et al.:
Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimers disease.
Proc. Natl. Acad. Sci. U.S.A.
2007
104: 9434-9439
|
| 21383494 |
Sultana R et al.:
Increased Protein and Lipid Oxidative Damage in Mitochondria Isolated from Lymphocytes from Patients with Alzheimers Disease: Insights into the Role of Oxidative Stress in Alzheimers Disease and Initial Investigations into a Potential Biomarker for this Dementing Disorder.
J. Alzheimers Dis.
2011
24: 77-84
|
| 21187585 |
Schrag M et al.:
Effect of cerebral amyloid angiopathy on brain iron, copper, and zinc in Alzheimers disease.
J. Alzheimers Dis.
2011
24: 137-149
|
| 21187587 |
Zhou R et al.:
Association between Bone Mineral Density and the Risk of Alzheimers Disease.
J. Alzheimers Dis.
2011
24: 101-108
|
| 21376707 |
Li W et al.:
Regulation of matrix metalloproteinase 2 by oligomeric amyloid beta protein.
Brain Res.
2011
1387: 141-148
|
| 21148560 |
Jawhar S et al.:
Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice.
J. Biol. Chem.
2011
286: 4454-4460
|
| 19863057 |
Buchholz M et al.:
Inhibitors for human glutaminyl cyclase by structure based design and bioisosteric replacement.
J. Med. Chem.
2009
52: 7069-7080
|
| 20128815 |
Manthey D et al.:
The selective beta1-adrenoceptor antagonist nebivolol is a potential oestrogen receptor agonist with neuroprotective abilities.
Br. J. Pharmacol.
2010
159: 1264-1273
|
| 21288892 |
Huang KF et al.:
Structures of Human Golgi-resident Glutaminyl Cyclase and Its Complexes with Inhibitors Reveal a Large Loop Movement upon Inhibitor Binding.
J. Biol. Chem.
2011
286
|
| 18836460 |
Schilling S et al.:
Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimers disease-like pathology.
Nat. Med.
2008
14: 1106-1111
|
| 19342064 |
Shenk JC et al.:
The effect of acetyl-L-carnitine and R-alpha-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimers disease
J. Neurol. Sci.
2009
283: 199-206
|
| 20385883 |
Gu Y et al.:
Food combination and Alzheimer disease risk: a protective diet
Arch. Neurol.
2010
67: 699-706
|
| 20627092 |
Yamada K et al.:
Effect of a centrally active angiotensin-converting enzyme inhibitor, perindopril, on cognitive performance in a mouse model of Alzheimers disease.
Brain Res.
2010
1352: 176-186
|
| 20971085 |
Shi JQ et al.:
Anti-TNF-alpha reduces amyloid plaques and tau phosphorylation and induces CD11c-positive dendritic-like cell in the APP/PS1 transgenic mouse brains.
Brain Res.
2011
1368: 239-247
|
| 18926603 |
Julien C et al.:
High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model.
Neurobiol. Aging
2010
31: 1516-1531
|
| 19604602 |
DOnofrio M et al.:
Early inflammation and immune response mRNAs in the brain of AD11 anti-NGF mice.
Neurobiol. Aging
2011
32: 1007-1022
|
| 16813604 |
Akomolafe A et al.:
Genetic association between endothelial nitric oxide synthase and Alzheimer disease
Clin. Genet.
2006
70: 49-56
|
| 21127294 |
Austin SA et al.:
Endothelial nitric oxide modulates expression and processing of amyloid precursor protein.
Circ. Res.
2010
107: 1498-1502
|
| 19604603 |
Portelius E et al.:
A novel pathway for amyloid precursor protein processing
Neurobiol. Aging
2011
32: 1090-1098
|
| 19604604 |
Liu RM et al.:
Knockout of plasminogen activator inhibitor 1 gene reduces amyloid beta peptide burden in a mouse model of Alzheimers disease.
Neurobiol. Aging
2011
32: 1079-1089
|
| 19628305 |
Amadoro G et al.:
Endogenous Abeta causes cell death via early tau hyperphosphorylation.
Neurobiol. Aging
2011
32: 969-990
|
| 17534003 |
Gliebus G et al.:
The influence of beta-blockers on delayed memory function in people with cognitive impairment.
Am J Alzheimers Dis Other Demen
2007
22: 57-61
|
| 19805638 |
Takeda S et al.:
Angiotensin receptor blocker prevented beta-amyloid-induced cognitive impairment associated with recovery of neurovascular coupling.
Hypertension
2009
54: 1345-1352
|
| 21633502 |
Bigalke B et al.:
Adipocytokines and CD34 Progenitor Cells in Alzheimers Disease.
PLoS ONE
2011
6
|
| 21297254 |
Mateos L et al.:
Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimers disease
J. Alzheimers Dis.
2011
24: 669-679
|
| 21368380 |
Fiala M et al.:
MGAT3 mRNA: a biomarker for prognosis and therapy of Alzheimers disease by vitamin D and curcuminoids
J. Alzheimers Dis.
2011
25: 135-144
|
| 21157028 |
Gelber RP et al.:
Coffee intake in midlife and risk of dementia and its neuropathologic correlates.
J. Alzheimers Dis.
2011
23: 607-615
|
| 21321396 |
Carrasquillo MM et al.:
Replication of BIN1 association with Alzheimers disease and evaluation of genetic interactions
J. Alzheimers Dis.
2011
24: 751-758
|
| 21132329 |
Belbin O et al.:
Investigation of 15 of the top candidate genes for late-onset Alzheimers disease.
Hum. Genet.
2011
129: 273-282
|
| 21098976 |
Keller L et al.:
The obesity related gene, FTO, interacts with APOE, and is associated with Alzheimers disease risk: a prospective cohort study
J. Alzheimers Dis.
2011
23: 461-469
|
| 21321400 |
Tiribuzi R et al.:
Lysosomal beta-galactosidase and beta-hexosaminidase activities correlate with clinical stages of dementia associated with Alzheimers disease and type 2 diabetes mellitus
J. Alzheimers Dis.
2011
24: 785-797
|
| 21321389 |
Echeverria V et al.:
Cotinine reduces amyloid-beta aggregation and improves memory in Alzheimers disease mice
J. Alzheimers Dis.
2011
24: 817-835
|
| 20413858 |
Carlsson CM et al.:
Type 2 diabetes mellitus, dyslipidemia, and Alzheimers disease.
J. Alzheimers Dis.
2010
20: 711-722
|
| 18376061 |
Carlsson CM et al.:
Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimers disease.
J. Alzheimers Dis.
2008
13: 187-197
|
| 21536132 |
Butterfield DA et al.:
Cholesterol-independent neuroprotective and neurotoxic activities of statins: perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders
Pharmacol. Res.
2011
64: 180-186
|
| 20847439 |
Murphy MP et al.:
Changes in cognition and amyloid-beta processing with long term cholesterol reduction using atorvastatin in aged dogs.
J. Alzheimers Dis.
2010
22: 135-150
|
| 21345168 |
Heneka MT et al.:
Molecular mechanisms and therapeutic application of NSAIDs and derived compounds in Alzheimers disease.
Curr Alzheimer Res
2011
8: 115-131
|
| 20639188 |
Gulaj E et al.:
Kynurenine and its metabolites in Alzheimers disease patients
Adv Med Sci
2010
55: 204-211
|
| 17049675 |
Urbanelli L et al.:
Cathepsin D expression is decreased in Alzheimers disease fibroblasts.
Neurobiol. Aging
2008
29: 12-22
|
| 21416488 |
Green KN et al.:
ST101 induces a novel 17 kDa APP cleavage that precludes Abeta generation in vivo.
Ann. Neurol.
2011
69: 831-844
|
| 11786245 |
Sly LM et al.:
Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimers disease.
Brain Res. Bull.
2001
56: 581-588
|
| 21466683 |
Kok EH et al.:
CLU, CR1 and PICALM genes associate with Alzheimers-related senile plaques.
Alzheimers Res Ther
2011
3: 12
|
| 21391232 |
Chibnik LB et al.:
CR1 is associated with amyloid plaque burden and age-related cognitive decline.
Ann. Neurol.
2011
69: 560-569
|
| 16515786 |
Pedersen WA et al.:
Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice
Exp. Neurol.
2006
199: 265-273
|
| 21280074 |
Chu J et al.:
5-lipoxygenase as an endogenous modulator of amyloid beta formation in vivo.
Ann. Neurol.
2011
69: 34-46
|
| 21280075 |
Reitz C et al.:
SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimers disease risk.
Ann. Neurol.
2011
69: 47-64
|
| 21321391 |
Fragkouli A et al.:
Matrix metalloproteinase-9 participates in NGF-induced alpha-secretase cleavage of amyloid-beta protein precursor in PC12 cells
J. Alzheimers Dis.
2011
24: 705-719
|
| 21416485 |
Jayadev S et al.:
Familial prion disease with Alzheimer disease-like tau pathology and clinical phenotype.
Ann. Neurol.
2011
69: 712-720
|
| 21504563 |
Piette F et al.:
Masitinib as an adjunct therapy for mild-to-moderate Alzheimers disease: a randomised, placebo-controlled phase 2 trial.
Alzheimers Res Ther
2011
3: 16
|
| 21406112 |
Li B et al.:
Stem cell factor and granulocyte colony-stimulating factor reduce beta-amyloid deposits in the brains of APP/PS1 transgenic mice.
Alzheimers Res Ther
2011
3: 8
|
| 21193043 |
Barone E et al.:
Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action
Pharmacol. Res.
2011
63: 172-180
|
| 21335656 |
Perez-Gonzalez R et al.:
Leptin induces proliferation of neuronal progenitors and neuroprotection in a mouse model of Alzheimers disease.
J. Alzheimers Dis.
2011
24: 17-25
|
| 21633390 |
Garwood CJ et al.:
Astrocytes are important mediators of Abeta-induced neurotoxicity and tau phosphorylation in primary culture.
Cell Death Dis
2011
2: E167
|
| 21527912 |
Kumar S et al.:
Extracellular phosphorylation of the amyloid beta-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimers disease.
EMBO J.
2011
30: 2255-2265
|
| 21562267 |
Terwel D et al.:
Critical role of astroglial apolipoprotein E and liver X receptor-alpha expression for microglial Abeta phagocytosis.
J. Neurosci.
2011
31: 7049-7059
|
| 21817177 |
Yanagisawa K et al.:
[Newly approved drugs for Alzheimer disease: effectiveness and limitation].
Brain Nerve
2011
63: 863-868
|
| 19694182 |
Wang B et al.:
Schisandrin B protects rat cortical neurons against Abeta1-42-induced neurotoxicity.
Pharmazie
2009
64: 450-454
|
| 21037121 |
Starkstein SE et al.:
Anosognosia is a significant predictor of apathy in Alzheimers disease.
J Neuropsychiatry Clin Neurosci
2010
22: 378-383
|
| 20808100 |
Orfei MD et al.:
Anosognosia in mild cognitive impairment and mild Alzheimers disease: frequency and neuropsychological correlates.
Am J Geriatr Psychiatry
2010
18: 1133-1140
|
| 20555149 |
Sedaghat F et al.:
Brain SPECT findings of anosognosia in Alzheimers disease.
J. Alzheimers Dis.
2010
21: 641-647
|
| 20188013 |
Leicht H et al.:
Anosognosia in Alzheimers disease: the role of impairment levels in assessment of insight across domains.
J Int Neuropsychol Soc
2010
16: 463-473
|
| 17361039 |
Jacob CP et al.:
Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimers disease.
J. Alzheimers Dis.
2007
11: 97-116
|
| 21211392 |
Lei JK et al.:
[Change of serum ACTH and cortisol levels in Alzheimer disease and mild cognition impairment].
Zhonghua Yi Xue Za Zhi
2010
90: 2894-2896
|
| 20937084 |
Fleisher-Berkovich S et al.:
Distinct modulation of microglial amyloid beta phagocytosis and migration by neuropeptides (i).
J Neuroinflammation
2010
7: 61
|
| 21387370 |
Himeno E et al.:
Apomorphine treatment in Alzheimer mice promoting amyloid-beta degradation.
Ann. Neurol.
2011
69: 248-256
|
| 21448224 |
Di Paolo G et al.:
Linking lipids to Alzheimers disease: cholesterol and beyond.
Nat. Rev. Neurosci.
2011
12: 284-296
|
| 21147981 |
Oliveira TG et al.:
Phospholipase d2 ablation ameliorates Alzheimers disease-linked synaptic dysfunction and cognitive deficits.
J. Neurosci.
2010
30
|
| 21357679 |
Chapuis J et al.:
Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-beta precursor protein
Hum. Mol. Genet.
2011
20: 2026-2036
|
| 19196476 |
Prinzen C et al.:
Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice.
BMC Genomics
2009
10: 66
|
| 21672962 |
Rolyan H et al.:
Telomere shortening reduces Alzheimers disease amyloid pathology in mice.
Brain
2011
134: 2044-2056
|
| 21389082 |
Casas-Tinto S et al.:
The ER stress factor XBP1s prevents amyloid-beta neurotoxicity.
Hum. Mol. Genet.
2011
20: 2144-2160
|
| 18276079 |
Clement AB et al.:
Effects of neuron-specific ADAM10 modulation in an in vivo model of acute excitotoxic stress.
Neuroscience
2008
152: 459-468
|
| 17722071 |
Shimmyo Y et al.:
Multifunction of myricetin on A beta: neuroprotection via a conformational change of A beta and reduction of A beta via the interference of secretases.
J. Neurosci. Res.
2008
86: 368-377
|
| 20592218 |
Mitterreiter S et al.:
Bepridil and amiodarone simultaneously target the Alzheimers disease beta- and gamma-secretase via distinct mechanisms.
J. Neurosci.
2010
30: 8974-8983
|
| 18391946 |
Berman DE et al.:
Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism
Nat. Neurosci.
2008
11: 547-554
|
| 19109907 |
OConnor T et al.:
Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.
Neuron
2008
60: 988-1009
|
| 20492361 |
Xu J et al.:
Actin interaction and regulation of cyclin-dependent kinase 5/p35 complex activity
J. Neurochem.
2011
116: 192-204
|
| 20348102 |
Lammich S et al.:
Expression of the anti-amyloidogenic secretase ADAM10 is suppressed by its 5-untranslated region.
J. Biol. Chem.
2010
285
|
| 20427278 |
Ullrich S et al.:
The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein.
J. Biol. Chem.
2010
285
|
| 21955788 |
Zhang L et al.:
Identifying Tmem59 related gene regulatory network of mouse neural stem cell from a compendium of expression profiles.
BMC Syst Biol
2011
5: 152
|
| 21413990 |
Lichtenthaler SF et al.:
Regulated intramembrane proteolysis--lessons from amyloid precursor protein processing.
J. Neurochem.
2011
117: 779-796
|
| 21695060 |
Hogl S et al.:
Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and gamma-secretase.
PLoS ONE
2011
6
|
| 20676056 |
Kuhn PH et al.:
ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons.
EMBO J.
2010
29: 3020-3032
|
| 21460840 |
Hollingworth P et al.:
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimers disease
Nat. Genet.
2011
43: 429-435
|
| 19879754 |
Baumann S et al.:
NSAID-derived gamma-secretase modulators. Part III: Membrane anchoring.
Bioorg. Med. Chem. Lett.
2009
19: 6986-6990
|
| 21689411 |
Ferris SH et al.:
Analyzing the impact of 23 mg/day donepezil on language dysfunction in moderate to severe Alzheimers disease.
Alzheimers Res Ther
2011
3: 22
|
| 19552690 |
Lu P et al.:
Silibinin prevents amyloid beta peptide-induced memory impairment and oxidative stress in mice
Br. J. Pharmacol.
2009
157: 1270-1277
|
| 12714508 |
Hundhausen C et al.:
The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion
Blood
2003
102: 1186-1195
|
| 21881209 |
Krohn M et al.:
Cerebral amyloid-beta proteostasis is regulated by the membrane transport protein ABCC1 in mice
J. Clin. Invest.
2011
121: 3924-3931
|
| 21035623 |
Craig-Schapiro R et al.:
YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimers disease.
Biol. Psychiatry
2010
68: 903-912
|
| 16371011 |
Glatz DC et al.:
The alternative splicing of tau exon 10 and its regulatory proteins CLK2 and TRA2-BETA1 changes in sporadic Alzheimers disease.
J. Neurochem.
2006
96: 635-644
|
| 21470964 |
Qian W et al.:
Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A.
Nucleic Acids Res.
2011
39: 6161-6171
|
| 21281635 |
Jung HJ et al.:
Increased expression of three-repeat isoforms of tau contributes to tau pathology in a rat model of chronic type 2 diabetes.
Exp. Neurol.
2011
228: 232-241
|
| 21367856 |
Shi J et al.:
Cyclic AMP-dependent protein kinase regulates the alternative splicing of tau exon 10: a mechanism involved in tau pathology of Alzheimer disease.
J. Biol. Chem.
2011
286
|
| 21807765 |
Smith PY et al.:
MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy.
Hum. Mol. Genet.
2011
20: 4016-4024
|
| 20930824 |
author information missing
article information missing
|
| 16943417 |
Wu JY et al.:
SRp54 (SFRS11), a regulator for tau exon 10 alternative splicing identified by an expression cloning strategy.
Mol. Cell. Biol.
2006
26: 6739-6747
|
| 15972296 |
Prinzen C et al.:
Genomic structure and functional characterization of the human ADAM10 promoter.
FASEB J.
2005
19: 1522-1524
|
| 19608551 |
Kim M et al. et al.:
Potential late-onset Alzheimers disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity
Hum. Mol. Genet.
2009
18: 3987-3996
|
| 19498037 |
Rodriguez-Martin T et al.:
Correction of tau mis-splicing caused by FTDP-17 MAPT mutations by spliceosome-mediated RNA trans-splicing
Hum. Mol. Genet.
2009
18: 3266-3273
|
| 2181826 |
Godfrey DG et al.:
The distribution, relationships and identification of enzymic variants within the subgenus Trypanozoon.
Adv. Parasitol.
1990
29: 1-74
|
| 16777844 |
Kar A et al.:
RBM4 interacts with an intronic element and stimulates tau exon 10 inclusion.
J. Biol. Chem.
2006
281
|
| 21333649 |
Qian W et al.:
Splicing factor SC35 promotes tau expression through stabilization of its mRNA.
FEBS Lett.
2011
585: 875-880
|
| 20615469 |
Chen KL et al.:
Amyloid-beta peptide alteration of tau exon-10 splicing via the GSK3beta-SC35 pathway
Neurobiol. Dis.
2010
40: 378-385
|
| 19502709 |
Kooistra J et al.:
A new function of human HtrA2 as an amyloid-beta oligomerization inhibitor.
J. Alzheimers Dis.
2009
17: 281-294
|
| 21365281 |
Gutierrez-Lopez MD et al.:
The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9.
Cell. Mol. Life Sci.
2011
68: 3275-3292
|
| 20194618 |
Ohe K et al.:
HMGA1a trapping of U1 snRNP at an authentic 5 splice site induces aberrant exon skipping in sporadic Alzheimers disease.
Mol. Cell. Biol.
2010
30: 2220-2228
|
| 11193153 |
Fahrenholz F et al.:
Alpha-secretase activity of the disintegrin metalloprotease ADAM 10. Influences of domain structure.
Ann. N. Y. Acad. Sci.
2000
920: 215-222
|
| 21799908 |
Pietrzak M et al.:
Epigenetic silencing of nucleolar rRNA genes in Alzheimers disease.
PLoS ONE
2011
6
|
| 21835916 |
Wilkinson K et al.:
A high content drug screen identifies ursolic acid as an inhibitor of amyloid beta protein interactions with its receptor CD36.
J. Biol. Chem.
2011
286
|
| 15695522 |
Wang Y et al.:
Tau exons 2 and 10, which are misregulated in neurodegenerative diseases, are partly regulated by silencers which bind a SRp30c.SRp55 complex that either recruits or antagonizes htra2beta1.
J. Biol. Chem.
2005
280
|
| 22278060 |
Israel MA et al.:
Probing sporadic and familial Alzheimers disease using induced pluripotent stem cells
Nature
2012
482: 216-220
|
| 15615629 |
Andreadis A et al.:
Tau gene alternative splicing: expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases.
Biochim. Biophys. Acta
2005
1739: 91-103
|
| 21114897 |
Radenahmad N et al.:
Young coconut juice, a potential therapeutic agent that could significantly reduce some pathologies associated with Alzheimers disease: novel findings.
Br. J. Nutr.
2011
105: 738-746
|
| 21492498 |
Barak Y et al.:
Escitalopram versus risperidone for the treatment of behavioral and psychotic symptoms associated with Alzheimers disease: a randomized double-blind pilot study
Int Psychogeriatr
2011
23: 1515-1519
|
| 15890777 |
Zhou S et al.:
CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimers disease amyloid beta-peptide production.
Proc. Natl. Acad. Sci. U.S.A.
2005
102: 7499-7504
|
| 21343338 |
Kar A et al.:
RNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5 splice site.
Mol. Cell. Biol.
2011
31: 1812-1821
|
| 21902456 |
Hedskog L et al.:
Strategic role for mitochondria in Alzheimers disease and cancer
Antioxid. Redox Signal.
2012
16: 1476-1491
|
| 21707856 |
Kato K et al.:
Protein kinase C stabilizes X-linked inhibitor of apoptosis protein (XIAP) through phosphorylation at Ser(87) to suppress apoptotic cell death.
Psychogeriatrics
2011
11: 90-97
|
| 21054783 |
Hedskog L et al.:
gamma-Secretase complexes containing caspase-cleaved presenilin-1 increase intracellular Abeta(42) /Abeta(40) ratio.
J. Cell. Mol. Med.
2011
15: 2150-2163
|
| 19389700 |
Quintanilla RA et al.:
Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: implications for the pathogenesis of Alzheimer disease
J. Biol. Chem.
2009
284
|
| 22079237 |
Alldred MJ et al.:
Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction
Neurobiol. Dis.
2012
45: 751-762
|
| 20570249 |
Yang H et al.:
Amelioration of the Alzheimers disease phenotype by absence of 12/15-lipoxygenase
Biol. Psychiatry
2010
68: 922-929
|
| 21900234 |
Bate C et al.:
Amyloid-beta-induced synapse damage is mediated via cross-linkage of cellular prion proteins.
J. Biol. Chem.
2011
286
|
| 21715329 |
Xue Y et al.:
Crystal structure of the E2 domain of amyloid precursor protein-like protein 1 in complex with sucrose octasulfate.
J. Biol. Chem.
2011
286
|
| 22101739 |
Samy AS et al.:
Regulation of IL-1beta-induced cyclooxygenase-2 expression by interactions of Abeta peptide, apolipoprotein E and nitric oxide in human neuroglioma
J. Mol. Neurosci.
2012
47: 533-545
|
| 21795680 |
Griffiths HH et al.:
Prion protein interacts with BACE1 protein and differentially regulates its activity toward wild type and Swedish mutant amyloid precursor protein.
J. Biol. Chem.
2011
286
|
| 19671904 |
Scarmeas N et al.:
Physical activity, diet, and risk of Alzheimer disease.
JAMA
2009
302: 627-637
|
| 20009056 |
Lieb W et al.:
Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging.
JAMA
2009
302: 2565-2572
|
| 19887909 |
Kellett KA et al.:
Prion protein and Alzheimer disease.
Prion
2009
3: 190-194
|
| 20819221 |
Bitel CL et al.:
Increased expression and local accumulation of the prion protein, Alzheimer Abeta peptides, superoxide dismutase 1, and nitric oxide synthases 1 & 2 in muscle in a rabbit model of diabetes.
BMC Physiol.
2010
10: 18
|
| 22072713 |
Murakami K et al.:
SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid beta protein oligomerization and memory loss in mouse model of Alzheimer disease
J. Biol. Chem.
2011
286
|
| 21694453 |
Novak P et al.:
Tauons and prions: infamous cousins?
J. Alzheimers Dis.
2011
26: 413-430
|
| 20473510 |
Reiniger L et al.:
Tau, prions and Abeta: the triad of neurodegeneration
Acta Neuropathol.
2011
121: 5-20
|
| 22100763 |
Kudo W et al.:
Cellular prion protein is essential for oligomeric amyloid-beta-induced neuronal cell death.
Hum. Mol. Genet.
2012
21: 1138-1144
|
| 22028219 |
Jucker M et al.:
Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders.
Ann. Neurol.
2011
70: 532-540
|
| 22017494 |
Rosen RF et al.:
Exogenous seeding of cerebral beta-amyloid deposition in betaAPP-transgenic rats
J. Neurochem.
2012
120: 660-666
|
| 21699076 |
Szymanski P et al.:
Design, synthesis and biological evaluation of new 2-benzoxazolinone derivatives as potential cholinesterase inhibitors for therapy of alzheimers disease
Pharmazie
2011
66: 399-403
|
| 20598287 |
Grimmer T et al.:
Progression of cerebral amyloid load is associated with the apolipoprotein E epsilon4 genotype in Alzheimers disease
Biol. Psychiatry
2010
68: 879-884
|
| 20400860 |
Khalifa NB et al.:
What is the role of amyloid precursor protein dimerization
Cell Adh Migr
2010
4: 268-272
|
| 17050537 |
Kuan YH et al.:
PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2
J. Biol. Chem.
2006
281
|
| 16230627 |
Rodriguez-Martin T et al.:
Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: implications for tauopathies
Proc. Natl. Acad. Sci. U.S.A.
2005
102
|
| 22077634 |
Sheng B et al.:
Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimers disease
J. Neurochem.
2012
120: 419-429
|
| 19273754 |
Qin W et al.:
PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia
Arch. Neurol.
2009
66: 352-361
|
| 21255795 |
Zhang Y et al.:
The -1082G/A polymorphism in IL-10 gene is associated with risk of Alzheimers disease: a meta-analysis
J. Neurol. Sci.
2011
303: 133-138
|
| 20479757 |
Conejero-Goldberg C et al.:
Molecular signatures in post-mortem brain tissue of younger individuals at high risk for Alzheimers disease as based on APOE genotype
Mol. Psychiatry
2011
16: 836-847
|
| 17998437 |
Li H et al.:
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease
Arch. Neurol.
2008
65: 45-53
|
| 17684015 |
Huttunen HJ et al.:
HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation
J. Biol. Chem.
2007
282
|
| 18292081 |
Kotilinek LA et al.:
Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity
Brain
2008
131: 651-664
|
| 19943124 |
Rothman SM et al.:
Adverse stress, hippocampal networks, and Alzheimers disease
Neuromolecular Med.
2010
12: 56-70
|
| 22275252 |
Chu J et al.:
Transcriptional regulation of beta-secretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments
Ann. Neurol.
2012
71: 57-67
|
| 18021299 |
Tachida Y et al.:
Interleukin-1 beta up-regulates TACE to enhance alpha-cleavage of APP in neurons: resulting decrease in Abeta production
J. Neurochem.
2008
104: 1387-1393
|
| 18587388 |
Yuzwa SA et al.:
A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo
Nat. Chem. Biol.
2008
4: 483-490
|
| 17940659 |
Dias WB et al.:
O-GlcNAc modification in diabetes and Alzheimers disease
Mol Biosyst
2007
3: 766-772
|
| 19122823 |
Bajic VP et al.:
Is the time dimension of the cell cycle re-entry in AD regulated by centromere cohesion dynamics
Biosci Hypotheses
2008
1: 156-161
|
| 15974909 |
Ringman JM et al.:
A potential role of the curry spice curcumin in Alzheimers disease
Curr Alzheimer Res
2005
2: 131-136
|
| 18815129 |
Ono K et al.:
Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity
J. Biol. Chem.
2008
283
|
| 18032783 |
Nixon RA et al.:
Autophagy, amyloidogenesis and Alzheimer disease
J. Cell. Sci.
2007
120: 4081-4091
|
| 21968187 |
Klug W et al.:
Phosphorylation of LRP1 regulates the interaction with Fe65
FEBS Lett.
2011
585: 3229-3235
|
| 16195917 |
Mikol J et al.:
Extensive cortico-subcortical lesions in Wilsons disease: clinico-pathological study of two cases
Acta Neuropathol.
2005
110: 451-458
|
| 22264991 |
Chen R et al.:
Elevation of serum TNF-alpha levels in mild and moderate Alzheimer patients with daytime sleepiness
J. Neuroimmunol.
2012
244: 97-102
|
| 22349686 |
Spalletta G et al.:
Anosognosia and neuropsychiatric symptoms and disorders in mild Alzheimer disease and mild cognitive impairment
J. Alzheimers Dis.
2012
29: 761-772
|
| 21129451 |
Jardanhazi-Kurutz D et al.:
Distinct adrenergic system changes and neuroinflammation in response to induced locus ceruleus degeneration in APP/PS1 transgenic mice
Neuroscience
2011
176: 396-407
|
| 11470313 |
Strausak D et al.:
Copper in disorders with neurological symptoms: Alzheimers, Menkes, and Wilson diseases
Brain Res. Bull.
2001
55: 175-185
|
| 20493925 |
Song H et al.:
Association between haplotype -88G/25G in A2M with Alzheimers disease
Neurosci. Lett.
2010
479: 143-145
|
| 9697696 |
Blacker D et al.:
Alpha-2 macroglobulin is genetically associated with Alzheimer disease
Nat. Genet.
1998
19: 357-360
|
| 21216965 |
Chen WT et al.:
Distinct effects of Zn2+, Cu2+, Fe3+, and Al3+ on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofibril formation
J. Biol. Chem.
2011
286: 9646-9656
|
| 16236446 |
Deary IJ et al.:
Polymorphisms in the gene encoding 11B-hydroxysteroid dehydrogenase type 1 (HSD11B1) and lifetime cognitive change
Neurosci. Lett.
2006
393: 74-77
|
| 14583441 |
de Quervain DJ et al.:
Glucocorticoid-related genetic susceptibility for Alzheimers disease
Hum. Mol. Genet.
2004
13: 47-52
|
| 11257240 |
Rasmuson S et al.:
Increased glucocorticoid production and altered cortisol metabolism in women with mild to moderate Alzheimers disease
Biol. Psychiatry
2001
49: 547-552
|
| 20157240 |
Souza-Talarico JN et al.:
Relationship between cortisol levels and memory performance may be modulated by the presence or absence of cognitive impairment: evidence from healthy elderly, mild cognitive impairment and Alzheimers disease subjects
J. Alzheimers Dis.
2010
19: 839-848
|
| 22660329 |
Nussbaum JM et al.:
Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-beta
Nature
2012
485: 651-655
|
| 22654059 |
Barrett PJ et al.:
The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol
Science
2012
336: 1168-1171
|
| 18482978 |
Tolia A et al.:
Transmembrane domain 9 of presenilin determines the dynamic conformation of the catalytic site of gamma-secretase
J. Biol. Chem.
2008
283
|
| 20871650 |
Shawkatova I et al.:
No association between cytokine gene polymorphism and risk of Alzheimers disease in Slovaks
Acta Neurobiol Exp (Wars)
2010
70: 303-307
|
| 22178568 |
Fang M et al.:
The miR-124 regulates the expression of BACE1/beta-secretase correlated with cell death in Alzheimers disease
Toxicol. Lett.
2012
209: 94-105
|
| 18096514 |
Lee MR et al.:
Inhibition of APP intracellular domain (AICD) transcriptional activity via covalent conjugation with Nedd8
Biochem. Biophys. Res. Commun.
2008
366: 976-981
|
| 22506131 |
Borquez DA et al.:
The amyloid precursor protein intracellular domain-fe65 multiprotein complexes: a challenge to the amyloid hypothesis for Alzheimers disease
Int J Alzheimers Dis
2012
2012
|
| 19282473 |
Stante M et al.:
Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 5093-5098
|
| 15331662 |
von Rotz RC et al.:
The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor
J. Cell. Sci.
2004
117: 4435-4448
|
| 22122663 |
Pardossi-Piquard R et al.:
The physiology of the beta-amyloid precursor protein intracellular domain AICD
J. Neurochem.
2012
120: 109-124
|
| 17093061 |
Muller T et al.:
Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD)
Mol. Biol. Cell
2007
18: 201-210
|
| 15708439 |
Caccamo A et al.:
Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders
Neurobiol. Aging
2005
26: 645-654
|
| 22563077 |
Maesako M et al.:
Exercise Is More Effective than Diet Control in Preventing High Fat Diet-induced beta-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic Mice
J. Biol. Chem.
2012
287
|
| 22303443 |
Westin K et al.:
CCL2 is associated with a faster rate of cognitive decline during early stages of Alzheimers disease
PLoS ONE
2012
7
|
| 22805778 |
Hoshi A et al.:
Characteristics of aquaporin expression surrounding senile plaques and cerebral amyloid angiopathy in Alzheimer disease
J. Neuropathol. Exp. Neurol.
2012
71: 750-759
|
| 22801501 |
Jonsson T et al.:
A mutation in APP protects against Alzheimers disease and age-related cognitive decline
Nature
2012
488: 96-99
|
| 10742146 |
Lu DC et al.:
A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor
Nat. Med.
2000
6: 397-404
|
| 14557245 |
Chen Y et al.:
APP-BP1 mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimers disease brain
J. Cell Biol.
2003
163: 27-33
|
| 12533840 |
Dil Kuazi A et al.:
NEDD8 protein is involved in ubiquitinated inclusion bodies
J. Pathol.
2003
199: 259-266
|
| 18801622 |
Guldiken S et al.:
Subclinical Cushings syndrome is a potential cause of metabolic dementia and rapidly progressive Alzheimer-type dementia
Med. Hypotheses
2008
71: 703-705
|
| 16125145 |
Elgh E et al.:
Cognitive dysfunction, hippocampal atrophy and glucocorticoid feedback in Alzheimers disease
Biol. Psychiatry
2006
59: 155-161
|
| 10722740 |
Chen Y et al.:
The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons
J. Biol. Chem.
2000
275: 8929-8935
|
| 21880910 |
Li X et al.:
Neuronal production of transthyretin in human and murine Alzheimers disease: is it protective
J. Neurosci.
2011
31
|
| 15192323 |
Chen YZ et al.:
APP induces neuronal apoptosis through APP-BP1-mediated downregulation of beta-catenin
Apoptosis
2004
9: 415-422
|
| 12777371 |
Weggen S et al.:
Abeta42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein (APP) and ErbB-4 receptor and signaling through the APP intracellular domain
J. Biol. Chem.
2003
278
|
| 20689579 |
Ghosal K et al.:
APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation
PLoS ONE
2010
5
|
| 21958873 |
Paris D et al.:
Anatabine lowers Alzheimers Abeta production in vitro and in vivo
Eur. J. Pharmacol.
2011
670: 384-391
|
| 16973241 |
Carter CJ et al.:
Convergence of genes implicated in Alzheimers disease on the cerebral cholesterol shuttle: APP, cholesterol, lipoproteins, and atherosclerosis
Neurochem. Int.
2007
50: 12-38
|
| 22464332 |
Nakamura K et al.:
Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimers disease
Cell
2012
149: 232-244
|
| 18587408 |
Faghihi MA et al.:
Expression of a noncoding RNA is elevated in Alzheimers disease and drives rapid feed-forward regulation of beta-secretase
Nat. Med.
2008
14: 723-730
|
| 22915175 |
Singh-Manoux A et al.:
Obesity phenotypes in midlife and cognition in early old age: the Whitehall II cohort study
Neurology
2012
79: 755-762
|
| 22796576 |
Eyles DW et al.:
Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease
Front Neuroendocrinol
2013
34: 47-64
|
| 22591405 |
Qiao DL et al.:
Is vitamin D beneficial to Alzheimer disease? A surprising dilemma
CNS Neurosci Ther
2012
18: 601-603
|
| 21486290 |
Webster SJ et al.:
The acute effects of dimebolin, a potential Alzheimers disease treatment, on working memory in rhesus monkeys
Br. J. Pharmacol.
2011
164: 970-978
|
| 22942647 |
Sozio P et al.:
Transdermal donepezil on the treatment of Alzheimers disease
Neuropsychiatr Dis Treat
2012
8: 361-368
|
| 21502597 |
Rafii MS et al.:
A phase II trial of huperzine A in mild to moderate Alzheimer disease
Neurology
2011
76: 1389-1394
|
| 22227962 |
Kummer MP et al.:
Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice
J Neuroimmune Pharmacol
2012
7: 165-172
|
| 22766135 |
Martins LC et al.:
Disease-specific expression of the serotonin-receptor 5-HT(2C) in natural killer cells in Alzheimers dementia
J. Neuroimmunol.
2012
251: 73-79
|
| 19072283 |
Owen JB et al.:
Proteomics-determined differences in the concanavalin-A-fractionated proteome of hippocampus and inferior parietal lobule in subjects with Alzheimers disease and mild cognitive impairment: implications for progression of AD
J. Proteome Res.
2009
8: 471-482
|
| 22801742 |
Doecke JD et al.:
Blood-based protein biomarkers for diagnosis of Alzheimer disease
Arch. Neurol.
2012
69: 1318-1325
|
| 22329649 |
Cai H et al.:
Metabolic dysfunction in Alzheimers disease and related neurodegenerative disorders
Curr Alzheimer Res
2012
9: 5-17
|
| 16843497 |
Rentzos M et al.:
Interleukin-12 is reduced in cerebrospinal fluid of patients with Alzheimers disease and frontotemporal dementia
J. Neurol. Sci.
2006
249: 110-114
|
| 23178247 |
Vom Berg J et al.:
Inhibition of IL-12/IL-23 signaling reduces Alzheimers disease-like pathology and cognitive decline
Nat. Med.
2012
18: 1812-1819
|
| 11137576 |
Szczepanik AM et al.:
IL-4, IL-10 and IL-13 modulate A beta(1--42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line
J. Neuroimmunol.
2001
113: 49-62
|
| 23157339 |
Arlt S et al.:
Genetic risk factors for depression in Alzheimer`s disease patients
Curr Alzheimer Res
2013
10: 72-81
|
| 22970774 |
Azizi G et al.:
The potential role of proinflammatory and antiinflammatory cytokines in Alzheimer disease pathogenesis
Immunopharmacol Immunotoxicol
2012
34: 881-895
|
| 19776284 |
Reed-Geaghan EG et al.:
CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation
J. Neurosci.
2009
29
|
| 21071836 |
Murata N et al.:
Silymarin attenuated the amyloid beta plaque burden and improved behavioral abnormalities in an Alzheimers disease mouse model
Biosci. Biotechnol. Biochem.
2010
74: 2299-2306
|
| 21185897 |
Yin F et al.:
Silibinin: a novel inhibitor of Abeta aggregation
Neurochem. Int.
2011
58: 399-403
|
| 22610069 |
Lehmann SM et al.:
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration
Nat. Neurosci.
2012
15: 827-835
|
| 19464758 |
Srikanth V et al.:
Advanced glycation endproducts and their receptor RAGE in Alzheimers disease
Neurobiol. Aging
2011
32: 763-777
|
| 23393093 |
Mori K et al.:
The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS
Science
2013
339: 1335-1338
|
| 23352322 |
Cacace R et al.:
C9orf72 G4C2 repeat expansions in Alzheimers disease and mild cognitive impairment
Neurobiol. Aging
2013
34: 1712
|
| 23150934 |
Guerreiro R et al.:
TREM2 variants in Alzheimers disease
N. Engl. J. Med.
2013
368: 117-127
|
| 19484711 |
Oulhaj A et al.:
Homocysteine as a predictor of cognitive decline in Alzheimers disease
Int J Geriatr Psychiatry
2010
25: 82-90
|
| 9823829 |
Clarke R et al.:
Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease
Arch. Neurol.
1998
55: 1449-1455
|
| 22964832 |
Xi Z et al.:
Investigation of c9orf72 in 4 neurodegenerative disorders
Arch. Neurol.
2012
69: 1583-1590
|
| 16688597 |
Rota E et al.:
Increased intrathecal TGF-beta1, but not IL-12, IFN-gamma and IL-10 levels in Alzheimers disease patients
Neurol. Sci.
2006
27: 33-39
|
| 9147373 |
Xu S et al.:
Increased incidence of anti-beta-amyloid autoantibodies secreted by Epstein-Barr virus transformed B cell lines from patients with Alzheimers disease
Mech. Ageing Dev.
1997
94: 213-222
|
| 21857683 |
Deng HX et al.:
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
Nature
2011
477: 211-215
|
| 20074050 |
Haapasalo A et al.:
Emerging role of Alzheimers disease-associated ubiquilin-1 in protein aggregation
Biochem. Soc. Trans.
2010
38: 150-155
|
| 21966562 |
Haapasalo A et al.:
Involvement of ubiquilin-1 transcript variants in protein degradation and accumulation
Commun Integr Biol
2011
4: 428-432
|
| 23162743 |
Ma QL et al.:
PAK in Alzheimer disease, Huntington disease and X-linked mental retardation
Cell Logist
2012
2: 117-125
|
| 21852239 |
Stieren ES et al.:
Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein
J. Biol. Chem.
2011
286
|
| 23204143 |
Yarchoan M et al.:
Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias
Brain
2012
135: 3749-3756
|
| 22745485 |
Kook SY et al.:
Abeta(1)(-)(4)(2)-RAGE interaction disrupts tight junctions of the blood-brain barrier via Ca(2)(+)-calcineurin signaling
J. Neurosci.
2012
32: 8845-8854
|
| 23208281 |
Ashe KH et al.:
Prions, prionoids and pathogenic proteins in Alzheimer disease
Prion
2013
7: 55-59
|
| 21969301 |
Bakalash S et al.:
Egr1 expression is induced following glatiramer acetate immunotherapy in rodent models of glaucoma and Alzheimers disease
Invest. Ophthalmol. Vis. Sci.
2011
52: 9033-9046
|
| 23667698 |
Takasugi N et al.:
FTY720/Fingolimod, a Sphingosine Analogue, Reduces Amyloid-beta Production in Neurons
PLoS ONE
2013
8
|
| 15923191 |
Tamboli IY et al.:
Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide
J. Biol. Chem.
2005
280
|
| 20110603 |
Rojo LE et al.:
Selective interaction of lansoprazole and astemizole with tau polymers: potential new clinical use in diagnosis of Alzheimers disease
J. Alzheimers Dis.
2010
19: 573-589
|
| 10226937 |
Baran H et al.:
Kynurenine metabolism in Alzheimers disease
J Neural Transm
1999
106: 165-181
|
| 17017544 |
Nemeth H et al.:
Kynurenines, Parkinsons disease and other neurodegenerative disorders: preclinical and clinical studies
J. Neural Transm. Suppl.
2006
70: 285-304
|
| 21538537 |
De Deyn PP et al.:
Tolerability of extended-release quetiapine fumarate compared with immediate-release quetiapine fumarate in older patients with Alzheimers disease with symptoms of psychosis and/or agitation: a randomised, double-blind, parallel-group study
Int J Geriatr Psychiatry
2012
27: 296-304
|
| 15465626 |
Walter A et al.:
Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients
Neurobiol. Aging
2004
25: 1299-1303
|
| 16227558 |
Serot JM et al.:
Homocysteine and methylmalonic acid concentrations in cerebrospinal fluid: relation with age and Alzheimers disease
J. Neurol. Neurosurg. Psychiatr.
2005
76: 1585-1587
|
| 23365075 |
Browne TC et al.:
IFN-gamma Production by amyloid beta-specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimers disease
J. Immunol.
2013
190: 2241-2251
|
| 19199127 |
Leoni V et al.:
Oxysterols as markers of neurological disease--a review
Scand. J. Clin. Lab. Invest.
2009
69: 22-25
|
| 11027840 |
Bretillon L et al.:
Plasma levels of 24S-hydroxycholesterol in patients with neurological diseases
Neurosci. Lett.
2000
293: 87-90
|
| 23666171 |
Leoni V et al.:
Diagnostic power of 24S-hydroxycholesterol in cerebrospinal fluid: candidate marker of brain health
J. Alzheimers Dis.
2013
36: 739-747
|
| 23285020 |
Hosokawa M et al.:
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
PLoS ONE
2012
7
|
| 23435411 |
Lira-De Leon KI et al.:
Molecular mechanism of tau aggregation induced by anionic and cationic dyes
J. Alzheimers Dis.
2013
35: 319-334
|
| 23443659 |
Crowe A et al.:
Aminothienopyridazines and methylene blue affect Tau fibrillization via cysteine oxidation
J. Biol. Chem.
2013
288
|
| 23653592 |
Xie L et al.:
Methylene blue induces macroautophagy through 5 adenosine monophosphate-activated protein kinase pathway to protect neurons from serum deprivation
Front Cell Neurosci
2013
7: 56
|
| 22377780 |
Hughes TM et al.:
Markers of cholesterol metabolism in the brain show stronger associations with cerebrovascular disease than Alzheimers disease
J. Alzheimers Dis.
2012
30: 53-61
|
| 20158567 |
Nilsson P et al.:
Gene therapy in Alzheimers disease - potential for disease modification
J. Cell. Mol. Med.
2010
14: 741-757
|
| 21383512 |
Mori K et al.:
Effects of Hericium erinaceus on amyloid beta(25-35) peptide-induced learning and memory deficits in mice
Biomed. Res.
2011
32: 67-72
|
| 18758067 |
Mori K et al.:
Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells
Biol. Pharm. Bull.
2008
31: 1727-1732
|
| 22078238 |
Costa A et al.:
Galanin and alpha-MSH autoantibodies in cerebrospinal fluid of patients with Alzheimers disease
J. Neuroimmunol.
2011
240-241: 114-120
|
| 21399480 |
Lauterbach EC et al.:
Psychotropic drug effects on gene transcriptomics relevant to Alzheimer disease
Alzheimer Dis Assoc Disord
2012
26: 1-7
|
| 23935582 |
Mariani S et al.:
Effects of hemochromatosis and transferrin gene mutations on peripheral iron dyshomeostasis in mild cognitive impairment and Alzheimers and Parkinsons diseases
Front Aging Neurosci
2013
5: 37
|
| 17234346 |
Salins P et al.:
Lovastatin protects human neurons against Abeta-induced toxicity and causes activation of beta-catenin-TCF/LEF signaling
Neurosci. Lett.
2007
412: 211-216
|
| 22654722 |
Heneka MT et al.:
Impact and Therapeutic Potential of PPARs in Alzheimers Disease
Curr Neuropharmacol
2011
9: 643-650
|
| 10078972 |
Pradier L et al.:
Mapping the APP/presenilin (PS) binding domains: the hydrophilic N-terminus of PS2 is sufficient for interaction with APP and can displace APP/PS1 interaction
Neurobiol. Dis.
1999
6: 43-55
|
| 15033165 |
Cardona-Gomez P et al.:
Estradiol inhibits GSK3 and regulates interaction of estrogen receptors, GSK3, and beta-catenin in the hippocampus
Mol. Cell. Neurosci.
2004
25: 363-373
|
| 24270855 |
Han J et al.:
OCIAD2 activates gamma-secretase to enhance amyloid beta production by interacting with nicastrin
Cell. Mol. Life Sci.
2014
71: 2561-2576
|
| 11740561 |
Kamal A et al.:
Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP
Nature
2001
414: 643-648
|
| 21298039 |
Gatta V et al.:
Microarray analysis on human neuroblastoma cells exposed to aluminum, beta(1-42)-amyloid or the beta(1-42)-amyloid aluminum complex
PLoS ONE
2011
6
|
| 24780254 |
Laurent C et al.:
Beneficial effects of caffeine in a transgenic model of Alzheimers disease-like tau pathology
Neurobiol. Aging
2014
35: 2079-2090
|
| 11278378 |
Kihara T et al.:
alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity
J. Biol. Chem.
2001
276
|
| 10681545 |
Wang HY et al.:
beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimers disease pathology
J. Biol. Chem.
2000
275: 5626-5632
|
| 24123152 |
Zhang L et al.:
Tyrosine phosphatase STEP61 negatively regulates amyloid beta-mediated ERK/CREB signaling pathways via alpha7 nicotinic acetylcholine receptors
J. Neurosci. Res.
2013
91: 1581-1590
|
| 23810791 |
Sokolov AN et al.:
Chocolate and the brain: neurobiological impact of cocoa flavanols on cognition and behavior
Neurosci Biobehav Rev
2013
37: 2445-2453
|
| 21982844 |
Williams RJ et al.:
Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease
Free Radic. Biol. Med.
2012
52: 35-45
|
| 24511465 |
Robin NC et al.:
Simvastatin Promotes Adult Hippocampal Neurogenesis by Enhancing Wnt/beta-Catenin Signaling
Stem Cell Reports
2013
2: 9-17
|
| 16230462 |
Ryan KA et al.:
Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain
J. Cell Biol.
2005
171: 327-335
|
| 18070361 |
Chen Y et al.:
Amyloid precursor protein modulates beta-catenin degradation
J Neuroinflammation
2007
4: 29
|
| 18234671 |
Magdesian MH et al.:
Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling
J. Biol. Chem.
2008
283: 9359-9368
|
| 25878270 |
Kan MJ et al.:
Arginine deprivation and immune suppression in a mouse model of Alzheimers disease
J. Neurosci.
2015
15: 5969-5982
|
| 25502766 |
Sun Y et al.:
Translational study of Alzheimers disease (AD) biomarkers from brain tissues in AbetaPP/PS1 mice and serum of AD patients
J. Alzheimers Dis.
2015
45: 269-282
|
| 22406198 |
Kim YH et al.:
Proteomic analysis of plasma from a Tau transgenic mouse
Int. J. Dev. Neurosci.
2012
30: 277-283
|
| 21912965 |
Boda E et al.:
Brain expression of Kv3 subunits during development, adulthood and aging and in a murine model of Alzheimers disease
J. Mol. Neurosci.
2012
3: 606-615
|
| 15485486 |
Angulo E et al.:
Up-regulation of the Kv3.4 potassium channel subunit in early stages of Alzheimers disease
J. Neurochem.
2004
3: 547-557
|
| 18449908 |
Poduslo SE et al.:
Genome screen of late-onset Alzheimers extended pedigrees identifies TRPC4AP by haplotype analysis
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2009
1: 50-55
|
| 21116278 |
Furney SJ et al.:
Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimers disease
Mol. Psychiatry
2011
16: 1130-1138
|
| 26458046 |
Mainz A et al.:
The chaperone alphaB-crystallin uses different interfaces to capture an amorphous and an amyloid client
|
| 26033219 |
Cecarini V et al.:
Effects of Ghrelin on the Proteolytic Pathways of Alzheimers Disease Neuronal Cells
|
| 25998028 |
Folch J et al.:
The role of leptin in the sporadic form of Alzheimers disease. Interactions with the adipokines amylin, ghrelin and the pituitary hormone prolactin
Life Sci.
2015
140: 19-28
|
| 23595620 |
Hokama M et al.:
Altered expression of diabetes-related genes in Alzheimers disease brains: the Hisayama study
Cereb. Cortex
2014
24: 2476-2488
|
| 26515689 |
Lin CL et al.:
Amyloid-beta suppresses AMP-activated protein kinase (AMPK) signaling and contributes to alpha-synuclein-induced cytotoxicity
Exp. Neurol.
2016
275: 84-98
|
| 22367557 |
Cai Z et al.:
Roles of AMP-activated protein kinase in Alzheimers disease
Neuromolecular Med.
2012
14: 1-14
|
| 26250687 |
Goedert M et al.:
NEURODEGENERATION. Alzheimers and Parkinsons diseases: The prion concept in relation to assembled Abeta, tau, and alpha-synuclein
Science
2015
349
|
| 22746245 |
Nunes MA et al.:
Microdose lithium treatment stabilized cognitive impairment in patients with Alzheimers disease
Curr Alzheimer Res
2013
10: 104-107
|
| 23246577 |
Lee E et al.:
Effect of conjugated linoleic acid, mu-calpain inhibitor, on pathogenesis of Alzheimers disease
Biochim. Biophys. Acta
2013
1831: 709-718
|
| 9848094 |
Torp R et al.:
GADD45 is induced in Alzheimers disease, and protects against apoptosis in vitro
Neurobiol. Dis.
1998
5: 245-252
|
| 28035934 |
author information missing
article information missing
|
| 28111074 |
Huang YA et al.:
ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Abeta Secretion
Cell
2017
168: 427-441.e21
|
| 25328986 |
Phillips MC et al.:
Apolipoprotein E isoforms and lipoprotein metabolism
IUBMB Life
2014
66: 616-623
|
| 11408727 |
Dupuy AM et al.:
The relationship between apolipoprotein E4 and lipid metabolism is impaired in Alzheimers disease
Gerontology
2001
47: 213-218
|
| 25280473 |
Ashbrook DG et al.:
Joint genetic analysis of hippocampal size in mouse and human identifies a novel gene linked to neurodegenerative disease
BMC Genomics
2014
15: 850
|
| 24456642 |
Couttas TA et al.:
Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimers disease pathogenesis
Acta Neuropathol Commun
2014
2: 9
|
| 10416513 |
Caramelli P et al.:
Increased apolipoprotein B serum concentration in Alzheimers disease
Acta Neurol. Scand.
1999
100: 61-63
|
| 24470773 |
Mielke MM et al.:
Clinical epidemiology of Alzheimers disease: assessing sex and gender differences
Clin Epidemiol
2014
6: 37-48
|
| 28240269 |
Suhre K et al. et al.:
Connecting genetic risk to disease end points through the human blood plasma proteome
Nat Commun
2017
8: 14357
|
| 21841246 |
Mosconi L et al.:
Reduced mitochondria cytochrome oxidase activity in adult children of mothers with Alzheimers disease
J. Alzheimers Dis.
2011
27: 483-490
|
| 25633671 |
Hull J et al.:
Regional Increase in the Expression of the BCAT Proteins in Alzheimers Disease Brain: Implications in Glutamate Toxicity
J. Alzheimers Dis.
2015
45: 891-905
|
| 26983404 |
Gallart-Palau X et al.:
Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimers disease with cerebrovascular disease
Mol Brain
2016
9: 27
|
| 26969397 |
Riedel BC et al.:
Age, APOE and sex: Triad of risk of Alzheimers disease
J. Steroid Biochem. Mol. Biol.
2016
160: 134-147
|
| 28107809 |
Kitamura Y et al.:
Plasma protein profiling for potential biomarkers in the early diagnosis of Alzheimers disease
Neurol. Res.
2017
39: 231-238
|
| 21857965 |
Obama T et al.:
Dietary cholesterol reduces plasma triacylglycerol in apolipoprotein E-null mice: suppression of lipin-1 and -2 in the glycerol-3-phosphate pathway
PLoS ONE
2011
6
|
| 18155511 |
Xu Z et al.:
Long-term phytosterol treatment alters gene expression in the liver of apo E-deficient mice
J. Nutr. Biochem.
2008
19: 545-554
|
| 17077142 |
Wang JM et al.:
Activation of estrogen receptor alpha increases and estrogen receptor beta decreases apolipoprotein E expression in hippocampus in vitro and in vivo
Proc. Natl. Acad. Sci. U.S.A.
2006
103
|
| 24444806 |
Panizzon MS et al.:
Interaction of APOE genotype and testosterone on episodic memory in middle-aged men
Neurobiol. Aging
2014
35: 1778
|
| 21423873 |
Elliott DA et al.:
Apolipoproteins in the brain: implications for neurological and psychiatric disorders
Clin Lipidol
2010
51: 555-573
|
| 14741101 |
DeMattos RB et al.:
ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo
Neuron
2004
41: 193-202
|
| 9547226 |
Stone DJ et al.:
Increased synaptic sprouting in response to estrogen via an apolipoprotein E-dependent mechanism: implications for Alzheimers disease
J. Neurosci.
1998
18: 3180-3185
|
| 22701550 |
Song F et al.:
Plasma apolipoprotein levels are associated with cognitive status and decline in a community cohort of older individuals
PLoS One
2012
7
|
| 18395206 |
Raber J et al.:
AR, apoE, and cognitive function
Horm Behav
2008
53: 706-715
|
| 0 |
author information missing
article information missing
|
| 28248224 |
Martins IJ et al.:
The Role of Clinical Proteomics, Lipidomics, and Genomics in the Diagnosis of Alzheimers Disease
|
| 7737971 |
Hamazaki H et al.:
Ca(2+)-dependent binding of human serum amyloid P component to Alzheimers beta-amyloid peptide
J. Biol. Chem.
1995
270
|
| 12214001 |
Kindy MS et al.:
Apolipoprotein Serum Amyloid A in Alzheimers Disease
J. Alzheimers Dis.
1999
1: 155-167
|
| 10329371 |
Chauhan VP et al.:
Binding of gelsolin, a secretory protein, to amyloid beta-protein
Biochem. Biophys. Res. Commun.
1999
258: 241-246
|
| 26980008 |
Ashby EL et al.:
Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia
Neurochem. Res.
2017
42: 306-319
|
| 28261376 |
Griffin JW et al.:
Amino Acid Catabolism in Alzheimers Disease Brain: Friend or Foe? }, authors { names std { { name ml Griffin JW, affil str Department of Biomedical Sciences, East Tennessee State University College of Medicine, Johnson City, TN 37614, USA
Oxid Med Cell Longev
2017
2017
|
| 28298292 |
Chang TY et al.:
Cellular cholesterol homeostasis and Alzheimers disease
J. Lipid Res.
2017
58: 2239-2254
|
| 27634977 |
Pistollato F et al.:
Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease
Nutr. Rev.
2016
74: 624-634
|
| 18657226 |
Ryu JK et al.:
A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimers disease brain
J. Cell. Mol. Med.
2009
13: 2911-2925
|
| 19863188 |
Roher AE et al.:
Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimers disease
Biomarkers
2009
14: 493-501
|
| 22883744 |
Cudaback E et al.:
Apolipoprotein C-I is an APOE genotype-dependent suppressor of glial activation
J Neuroinflammation
2012
9: 192
|
| 25938590 |
Fonteh AN et al.:
Sphingolipid metabolism correlates with cerebrospinal fluid Beta amyloid levels in Alzheimers disease
PLoS ONE
2015
10
|
| 28697566 |
Johansson P et al.:
Reduced Cerebrospinal Fluid Concentration of Apolipoprotein A-I in Patients with Alzheimers Disease
|
| 24952994 |
Mielke MM et al.:
Cerebrospinal fluid sphingolipids, beta-amyloid, and tau in adults at risk for Alzheimers disease
Neurobiol. Aging
2014
35: 2486-2494
|
| 23868911 |
Fonteh AN et al.:
Alterations in cerebrospinal fluid glycerophospholipids and phospholipase A2 activity in Alzheimers disease
J. Lipid Res.
2013
54: 2884-2897
|
| 22521584 |
Kosicek M et al.:
Elevated cerebrospinal fluid sphingomyelin levels in prodromal Alzheimers disease
Neurosci. Lett.
2012
516: 302-305
|
| 22835784 |
van Echten-Deckert G et al.:
Sphingolipids: critical players in Alzheimers disease
Prog. Lipid Res.
2012
51: 378-393
|
| 20953867 |
Kosicek M et al.:
Nano-HPLC-MS analysis of phospholipids in cerebrospinal fluid of Alzheimers disease patients--a pilot study
Anal Bioanal Chem
2010
398: 2929-2937
|
| 20452460 |
Haughey NJ et al.:
Roles for dysfunctional sphingolipid metabolism in Alzheimers disease neuropathogenesis
Biochim. Biophys. Acta
2010
1801: 878-886
|
| 20110596 |
Martin V et al.:
Lipid alterations in lipid rafts from Alzheimers disease human brain cortex
J. Alzheimers Dis.
2010
19: 489-502
|
| 18547682 |
He X et al.:
Deregulation of sphingolipid metabolism in Alzheimers disease
Neurobiol. Aging
2010
31: 398-408
|
| 17342407 |
Katsel P et al.:
Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimers disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimers disease? }, authors { names std { { name ml Katsel P, affil str Department of Psychiatry, The Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029-6575, USA. pavel.katsel@mssm.edu }, { name ml Li C }, { name ml Haroutunian V } } }, from journal { title { iso-jta Neurochem. Res
Neurochem. Res.
2007
32: 845-856
|
| 7699335 |
Mucke L et al.:
Protection against HIV-1 gp120-induced brain damage by neuronal expression of human amyloid precursor protein
J. Exp. Med.
1995
181: 1551-1556
|
| 14970312 |
Cutler RG et al.:
Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimers disease
Proc. Natl. Acad. Sci. U.S.A.
2004
101: 2070-2075
|
| 14748735 |
Alessenko AV et al.:
Connection of lipid peroxide oxidation with the sphingomyelin pathway in the development of Alzheimers disease
Biochem. Soc. Trans.
2004
32: 144-146
|
| 12358786 |
Han X et al.:
Substantial sulfatide deficiency and ceramide elevation in very early Alzheimers disease: potential role in disease pathogenesis
J. Neurochem.
2002
82: 809-818
|
| 19036474 |
Barrier L et al.:
Gender-dependent accumulation of ceramides in the cerebral cortex of the APP(SL)/PS1Ki mouse model of Alzheimers disease
Neurobiol. Aging
2010
31: 1843-1853
|
| 28341160 |
Toledo JB et al.:
Metabolic network failures in Alzheimers disease-A biochemical road map
|
| 17888544 |
Bandaru VV et al.:
ApoE4 disrupts sterol and sphingolipid metabolism in Alzheimers but not normal brain
Neurobiol. Aging
2009
30: 591-599
|
| 24368217 |
Kunzler J et al.:
APOE modulates the effect of estrogen therapy on Abeta accumulation EFAD-Tg mice
Neurosci. Lett.
2014
560: 131-136
|
| 24486621 |
Panchal M et al.:
Ceramides and sphingomyelinases in senile plaques
Neurobiol. Dis.
2014
65: 193-201
|
| 17064658 |
Park JH et al.:
Acid ceramidase and human disease
Biochim. Biophys. Acta
2006
1758: 2133-2138
|
| 26708713 |
Moser VA et al.:
Obesity and sex interact in the regulation of Alzheimers disease
Neurosci Biobehav Rev
2016
67: 102-118
|
| 24468113 |
Ceccom J et al.:
Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimers disease
Acta Neuropathol Commun
2014
2: 12
|
| 15610181 |
Huang Y et al.:
Elevation of the level and activity of acid ceramidase in Alzheimers disease brain
Eur. J. Neurosci.
2004
20: 3489-3497
|
| 20409323 |
Lorenzen A et al.:
Rapid and direct transport of cell surface APP to the lysosome defines a novel selective pathway
Mol Brain
2010
3: 11
|
| 14709545 |
Lee JT et al.:
Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway
J. Cell Biol.
2004
164: 123-131
|
| 23779114 |
Hanson AJ et al.:
Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trial
JAMA Neurol
2013
70: 972-980
|
| 21125201 |
Doruk H et al.:
The relationship between body mass index and incidental mild cognitive impairment, Alzheimers disease and vascular dementia in elderly
J Nutr Health Aging
2010
14: 834-838
|
| 26198711 |
Grimm A et al.:
Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-beta or hyperphosphorylated tau protein
Cell. Mol. Life Sci.
2016
73: 201-215
|
| 18295935 |
Schaeffer V et al.:
Dose-dependent and sequence-sensitive effects of amyloid-beta peptide on neurosteroidogenesis in human neuroblastoma cells
Neurochem. Int.
2008
52: 948-955
|
| 27163830 |
Kantarci K et al.:
Early Postmenopausal Transdermal 17beta-Estradiol Therapy and Amyloid-beta Deposition
J. Alzheimers Dis.
2016
53: 547-556
|
| 25443293 |
Dionisio PA et al.:
Amyloid-beta pathology is attenuated by tauroursodeoxycholic acid treatment in APP/PS1 mice after disease onset
Neurobiol. Aging
2015
36: 228-240
|
| 20569235 |
Jazwinski SM et al.:
HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging
Aging Cell
2010
9: 698-708
|
| 28035926 |
den Hoedt S et al.:
Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels
|
| 22470521 |
Grimm MO et al.:
Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimers disease pathology with ganglioside metabolism
PLoS ONE
2012
7
|
| 21543615 |
Takasugi N et al.:
BACE1 activity is modulated by cell-associated sphingosine-1-phosphate
J. Neurosci.
2011
31: 6850-6857
|
| 28301062 |
Enche Ady CNA et al.:
Metabolomic-guided discovery of Alzheimers disease biomarkers from body fluid
J. Neurosci. Res.
2017
95: 2005-2024
|
| 15084661 |
Kawarabayashi T et al.:
Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimers disease
J. Neurosci.
2004
24: 3801-3809
|
| 18096814 |
Williamson R et al.:
Membrane-bound beta-amyloid oligomers are recruited into lipid rafts by a fyn-dependent mechanism
FASEB J.
2008
22: 1552-1559
|
| 20739292 |
Lefterov I et al.:
Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice
J. Biol. Chem.
2010
285
|
| 27033548 |
Hong S et al.:
Complement and microglia mediate early synapse loss in Alzheimer mouse models
Science
2016
352: 712-716
|
| 18048067 |
Walker DG et al.:
Human postmortem brain-derived cerebrovascular smooth muscle cells express all genes of the classical complement pathway: a potential mechanism for vascular damage in cerebral amyloid angiopathy and Alzheimers disease
Microvasc. Res.
2008
75: 411-419
|
| 7575468 |
Munger JS et al.:
Lysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin S
Biochem. J.
1995
311: 299-305
|
| 11004532 |
Oyama R et al.:
Glutamine synthetase, hemoglobin alpha-chain, and macrophage migration inhibitory factor binding to amyloid beta-protein: their identification in rat brain by a novel affinity chromatography and in Alzheimers disease brain by immunoprecipitation
Biochim. Biophys. Acta
2000
1479: 91-102
|
| 25206748 |
Zhou X et al.:
Lipid rafts participate in aberrant degradative autophagic-lysosomal pathway of amyloid-beta peptide in Alzheimers disease
Neural Regen Res
2014
9: 92-100
|
| 16480949 |
Chen TY et al.:
The intracellular domain of amyloid precursor protein interacts with flotillin-1, a lipid raft protein
Biochem. Biophys. Res. Commun.
2006
342: 266-272
|
| 27814578 |
Canerina-Amaro A et al.:
Lipid raft ER signalosome malfunctions in menopause and Alzheimers disease
Front Biosci (Schol Ed)
2017
9: 111-126
|
| 2207271 |
Colombo MF et al.:
Hydration-dependent conformational states of hemoglobin. Equilibrium and kinetic behavior
Biophys. Chem.
1990
36: 33-39
|
| 9354781 |
author information missing
Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition
Nat. Genet.
1997
17: 263-264
|
| 22737128 |
Hicks DA et al.:
Lipid rafts and Alzheimers disease: protein-lipid interactions and perturbation of signaling
Front Physiol
2012
3: 189
|
| 24625793 |
Tiwari V et al.:
Pyruvate carboxylase and pentose phosphate fluxes are reduced in AbetaPP-PS1 mouse model of Alzheimers disease: a (1)(3)C NMR study
J. Alzheimers Dis.
2014
41: 387-399
|
| 18539594 |
Osenkowski P et al.:
Direct and potent regulation of gamma-secretase by its lipid microenvironment
J. Biol. Chem.
2008
283
|
| 20798852 |
Bjerke M et al.:
Confounding factors influencing amyloid Beta concentration in cerebrospinal fluid
|
| 20961856 |
Belyaev ND et al.:
The transcriptionally active amyloid precursor protein (APP) intracellular domain is preferentially produced from the 695 isoform of APP in a {beta}-secretase-dependent pathway
J. Biol. Chem.
2010
285
|
| 19028695 |
Cheng H et al.:
S-palmitoylation of gamma-secretase subunits nicastrin and APH-1
J. Biol. Chem.
2009
284: 1373-1384
|
| 29211722 |
Sorrentino V et al.:
Enhancing mitochondrial proteostasis reduces amyloid-beta proteotoxicity
|
| 26680489 |
Vankova M et al.:
Reduced sulfotransferase SULT2A1 activity in patients with Alzheimers disease
Physiol Res
2015
64: Suppl 2 S265-S273
|
| 26704533 |
Vankova M et al.:
Preliminary evidence of altered steroidogenesis in women with Alzheimers disease: Have the patients OLDER adrenal zona reticularis? }, authors { names std { { name ml Vankova M, affil str Institute of Endocrinology, Narodni 8, Prague 116 94, Czech Republic. Electronic address: mvankova@endo.cz
J. Steroid Biochem. Mol. Biol.
2016
158: 157-177
|
| 11427315 |
Schonknecht P et al.:
Reduced cerebrospinal fluid estradiol levels are associated with increased beta-amyloid levels in female patients with Alzheimers disease
Neurosci. Lett.
2001
307: 122-124
|
| 19186121 |
Davis CH et al.:
Interaction between amyloid-beta (1-42) peptide and phospholipid bilayers: a molecular dynamics study
Biophys. J.
2009
96: 785-797
|
| 16721824 |
Kim SI et al.:
Amyloid beta oligomerization is induced by brain lipid rafts
J. Cell. Biochem.
2006
99: 878-889
|
| 15718041 |
Pitto M et al.:
Enhanced GM1 ganglioside catabolism in cultured fibroblasts from Alzheimer patients
Neurobiol. Aging
2005
26: 833-838
|
| 22146133 |
Aly HF et al.:
Neuroprotective effects of dehydroepiandrosterone (DHEA) in rat model of Alzheimers disease
Acta Biochim. Pol.
2011
58: 513-520
|
| 28377712 |
Xia DY et al.:
PGC-1alpha or FNDC5 Is Involved in Modulating the Effects of Abeta1-42 Oligomers on Suppressing the Expression of BDNF, a Beneficial Factor for Inhibiting Neuronal Apoptosis, Abeta Deposition and Cognitive Decline of APP/PS1 Tg Mice
Front Aging Neurosci
2017
9: 65
|
| 26334640 |
Cieslik M et al.:
The Molecular Mechanism of Amyloid beta42 Peptide Toxicity: The Role of Sphingosine Kinase-1 and Mitochondrial Sirtuins
PLoS ONE
2015
10
|
| 29249916 |
Marksteiner J et al.:
Bile acid quantification of 20 plasma metabolites identifies lithocholic acid as a putative biomarker in Alzheimers disease
Metabolomics
2018
14: 1
|
| 11551970 |
Mathews PM et al.:
Alzheimers disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis
J. Biol. Chem.
2002
277: 5299-5307
|
| 16399207 |
Kar S et al.:
Cellular distribution of insulin-like growth factor-II/mannose-6-phosphate receptor in normal human brain and its alteration in Alzheimers disease pathology
Neurobiol. Aging
2006
27: 199-210
|
| 26993302 |
Wang Y et al.:
Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases
Mol. Neurobiol.
2017
54: 2636-2658
|
| 20050287 |
Martins IJ et al.:
Cholesterol metabolism and transport in the pathogenesis of Alzheimers disease
J. Neurochem.
2009
111: 1275-1308
|
| 28941727 |
Fernandez-de Retana S et al.:
Intravenous treatment with human recombinant ApoA-I Milano reduces beta amyloid cerebral deposition in the APP23-transgenic mouse model of Alzheimers disease
Neurobiol. Aging
2017
60: 116-128
|
| 26923602 |
Ben Halima S et al.:
Specific Inhibition of beta-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein
Cell Rep
2016
14: 2127-2141
|
| 27333034 |
Letronne F et al.:
ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimers Disease
EBioMedicine
2016
9: 278-292
|
| 27396345 |
Becker-Pauly C et al.:
Mice are not Men: ADAM30 Findings Emphasize a Broader Look Towards Murine Alzheimers Disease Models
EBioMedicine
2016
9: 19-20
|
| 18177262 |
Schechter I et al.:
Kinetic properties of cathepsin D and BACE 1 indicate the need to search for additional beta-secretase candidate(s)
Biol. Chem.
2008
389: 313-320
|
| 11741391 |
Petit-Turcotte C et al.:
Apolipoprotein C-I expression in the brain in Alzheimers disease
Neurobiol. Dis.
2001
8: 953-963
|
| 10828089 |
Demeester N et al.:
Characterization and functional studies of lipoproteins, lipid transfer proteins, and lecithin:cholesterol acyltransferase in CSF of normal individuals and patients with Alzheimers disease
J. Lipid Res.
2000
41: 963-974
|
| 20413849 |
Kim WS et al.:
Increased ATP-binding cassette transporter A1 expression in Alzheimers disease hippocampal neurons
J. Alzheimers Dis.
2010
21: 193-205
|
| 17361034 |
Strum JC et al.:
Rosiglitazone induces mitochondrial biogenesis in mouse brain
J. Alzheimers Dis.
2007
11: 45-51
|
| 26117841 |
Abdullah MM et al.:
Nutrigenetics of cholesterol metabolism: observational and dietary intervention studies in the postgenomic era
Nutr. Rev.
2015
73: 523-543
|
| 29115990 |
Martiskainen H et al.:
DHCR24 exerts neuroprotection upon inflammation-induced neuronal death
J Neuroinflammation
2017
14: 215
|
| 26628388 |
Hernandez-Jimenez M et al.:
Seladin-1/DHCR24 Is Neuroprotective by Associating EAAT2 Glutamate Transporter to Lipid Rafts in Experimental Stroke
Stroke
2016
47: 206-213
|
| 22910610 |
Feher A et al.:
Gender dependent effect of DHCR24 polymorphism on the risk for Alzheimers disease
Neurosci. Lett.
2012
526: 20-23
|
| 15954227 |
Peri A et al.:
Seladin-1 as a target of estrogen receptor activation in the brain: a new gene for a rather old story? }, authors { names std { { name ml Peri A, affil str Department of Clinical Physiopathology, Center for Research, Transfer and High Education on Chronic, Inflammatory, Degenerative and Neoplastic Disorders for the Development of Novel Therapies, University of Florence, Italy. a.peri@dfc.unifi.it }, { name ml Danza G }, { name ml Serio M } } }, from journal { title { iso-jta J. Endocrinol. Invest
J. Endocrinol. Invest.
2005
28: 285-293
|
| 19597241 |
Drzewinska J et al.:
[Seladin-1/DHCR24: a key protein of cell homeostasis and cholesterol biosynthesis]
Postepy Hig Med Dosw (Online)
2009
63: 318-330
|
| 18194465 |
Cecchi C et al.:
Seladin-1/DHCR24 protects neuroblastoma cells against Abeta toxicity by increasing membrane cholesterol content
J. Cell. Mol. Med.
2008
12: 1990-2002
|
| 20061018 |
Alberdi E et al.:
Amyloid beta oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors
Cell Calcium
2010
47: 264-272
|
| 25339759 |
Shibuya Y et al.:
Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Abeta1-42 clearance
J. Neurosci.
2014
34
|
| 29559883 |
Marin R et al.:
Estrogen Interactions With Lipid Rafts Related to Neuroprotection. Impact of Brain Ageing and Menopause
Front Neurosci
2018
12: 128
|
| 25168729 |
Fernandez-Echevarria C et al.:
Abeta promotes VDAC1 channel dephosphorylation in neuronal lipid rafts. Relevance to the mechanisms of neurotoxicity in Alzheimers disease
Neuroscience
2014
278: 354-366
|
| 28102888 |
Chen LH et al.:
Genetic Polymorphisms in Estrogen Metabolic Pathway Associated with Risks of Alzheimers Disease: Evidence from a Southern Chinese Population
J Am Geriatr Soc
2017
65: 332-339
|
| 27541017 |
Li Q et al.:
miR-98-5p Acts as a Target for Alzheimers Disease by Regulating Abeta Production Through Modulating SNX6 Expression
J. Mol. Neurosci.
2016
60: 413-420
|
| 23872114 |
Chua LM et al.:
The Kunitz-protease inhibitor domain in amyloid precursor protein reduces cellular mitochondrial enzymes expression and function
Biochem. Biophys. Res. Commun.
2013
437: 642-647
|
| 15882808 |
Thakur MK et al.:
Estradiol regulates APP mRNA alternative splicing in the mice brain cortex
Neurosci. Lett.
2005
381: 154-157
|
| 15357665 |
Feng Z et al.:
Long-term effects of melatonin or 17 beta-estradiol on improving spatial memory performance in cognitively impaired, ovariectomized adult rats
J. Pineal Res.
2004
37: 198-206
|
| 9223340 |
Xia W et al.:
Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease
Proc. Natl. Acad. Sci. U.S.A.
1997
94: 8208-8213
|
| 28731435 |
Hong H et al.:
Identification of Circulating miR-125b as a Potential Biomarker of Alzheimers Disease in APP/PS1 Transgenic Mouse
J. Alzheimers Dis.
2017
59: 1449-1458
|
| 26497032 |
Ren RJ et al.:
Peripheral Blood MicroRNA Expression Profiles in Alzheimers Disease: Screening, Validation, Association with Clinical Phenotype and Implications for Molecular Mechanism
Mol. Neurobiol.
2016
53: 5772-5781
|
| 8239286 |
Higgins LS et al.:
Transgenic mice expressing human beta-APP751, but not mice expressing beta-APP695, display early Alzheimers disease-like histopathology
Ann. N. Y. Acad. Sci.
1993
695: 224-227
|
| 20417581 |
Ishunina TA et al.:
Decreased alternative splicing of estrogen receptor-alpha mRNA in the Alzheimers disease brain
Neurobiol. Aging
2012
33: 286-296.e3
|
| 29869871 |
DelBove CE et al.:
The Fate of Nascent APP in Hippocampal Neurons: A Live Cell Imaging Study
ACS Chem Neurosci
2018
9: 2225-2232
|
| 2111579 |
Johnson SA et al.:
Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimers disease
Science
1990
248: 854-857
|
| 2881207 |
author information missing
The precursor of Alzheimers disease amyloid A4 protein resembles a cell-surface receptor
Nature
1987
325: 733-736
|
| 23684647 |
Nalivaeva NN et al.:
The amyloid precursor protein: a biochemical enigma in brain development, function and disease
FEBS Lett.
2013
587: 2046-2054
|
| 25695604 |
Shu R et al. et al.:
APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation
Cell Death Dis
2015
6: e1651
|
| 21172309 |
Long JM et al.:
MicroRNA-101 downregulates Alzheimers amyloid-beta precursor protein levels in human cell cultures and is differentially expressed
Biochem. Biophys. Res. Commun.
2011
404: 889-895
|
| 22733824 |
Long JM et al.:
MicroRNA-153 physiologically inhibits expression of amyloid-beta precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients
J. Biol. Chem.
2012
287
|
| 11441186 |
Cao X et al.:
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60
Science
2001
293: 115-120
|
| 21293490 |
Xu X et al.:
Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signalling
EMBO Rep.
2011
12: 216-222
|
| 10718932 |
Bowen RL et al.:
An association of elevated serum gonadotropin concentrations and Alzheimer disease?
J. Neuroendocrinol.
2000
12: 351-354
|
| 11560301 |
Short RA et al.:
Elevated gonadotropin levels in patients with Alzheimer disease
Mayo Clin. Proc.
2001
76: 906-909
|
| 12391612 |
Bowen RL et al.:
Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimers disease pathology
J. Neurosci. Res.
2002
70: 514-518
|
| 21368841 |
Turner AJ et al.:
Mediator: the missing link in amyloid precursor protein nuclear signalling
EMBO Rep.
2011
12: 180-181
|
| 15886752 |
Tsolaki M et al.:
Serum estradiol, progesterone, testosterone, FSH and LH levels in postmenopausal women with Alzheimers dementia
Hell J Nucl Med
2005
8: 39-42
|
| 26895791 |
Sajan M et al.:
Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1alpha and Increases in Abeta1-40/42 and Phospho-Tau May Abet Alzheimer Development
Diabetes
2016
65: 1892-1903
|
| 24832605 |
Wang X et al.:
FoxO mediates APP-induced AICD-dependent cell death
Cell Death Dis
2014
5: e1233
|
| 19478482 |
Corbo RM et al.:
Genetic variation of CYP19 (aromatase) gene influences age at onset of Alzheimers disease in women
Dement Geriatr Cogn Disord
2009
27: 513-518
|
| 21297427 |
Erten-Lyons D et al.:
Microcephaly genes and risk of late-onset Alzheimer disease
Alzheimer Dis Assoc Disord
2011
25: 276-282
|
| 24567336 |
Akhter R et al.:
The essential role of p53-up-regulated modulator of apoptosis (Puma) and its regulation by FoxO3a transcription factor in beta-amyloid-induced neuron death
J. Biol. Chem.
2014
289
|
| 12600719 |
Ueberham U et al.:
Cyclin C expression is involved in the pathogenesis of Alzheimers disease
Neurobiol. Aging
2003
24: 427-435
|
| 26455863 |
Fluteau A et al.:
The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain
Neurosci. Lett.
2015
609: 11-17
|
| 21354436 |
Herrera JL et al.:
Estradiol and tamoxifen differentially regulate a plasmalemmal voltage-dependent anion channel involved in amyloid-beta induced neurotoxicity
Steroids
2011
76: 840-844
|
| 27507672 |
Oikonomidi A et al.:
Homocysteine metabolism is associated with cerebrospinal fluid levels of soluble amyloid precursor protein and amyloid beta
J. Neurochem.
2016
139: 324-332
|
| 8624099 |
Sandbrink R et al.:
APP gene family. Alternative splicing generates functionally related isoforms
Ann. N. Y. Acad. Sci.
1996
777: 281-287
|
| 21865747 |
Corbo RM et al.:
Influence of variation in the follicle-stimulating hormone receptor gene (FSHR) and age at menopause on the development of Alzheimers disease in women
Dement Geriatr Cogn Disord
2011
32: 63-69
|
| 28538088 |
Koenig AM et al.:
Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study
Alzheimer Dis Assoc Disord
2017
31: 107-113
|
| 21839813 |
Yenkoyan K et al.:
Neuroprotective action of proline-rich polypeptide-1 in beta-amyloid induced neurodegeneration in rats
Brain Res. Bull.
2011
86: 262-271
|
| 9202320 |
Keller JN et al.:
Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal
J. Neurochem.
1997
69: 273-284
|
| 29055815 |
An Y et al. et al.:
Evidence for brain glucose dysregulation in Alzheimers disease
Alzheimers Dement
2018
14: 318-329
|
| 17023091 |
Hartai Z et al.:
Decreased serum and red blood cell kynurenic acid levels in Alzheimers disease
Neurochem. Int.
2007
50: 308-313
|
| 23274895 |
Arrieta-Cruz I et al.:
Evidence for a role of proline and hypothalamic astrocytes in the regulation of glucose metabolism in rats
Diabetes
2013
62: 1152-1158
|
| 26047665 |
Liemburg-Apers DC et al.:
Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism
Arch. Toxicol.
2015
89: 1209-1226
|
| 19595769 |
Ramirez CM et al.:
VDAC and ERalpha interaction in caveolae from human cortex is altered in Alzheimers disease
Mol. Cell. Neurosci.
2009
42: 172-183
|
| 20053478 |
Zhao L et al.:
17beta-Estradiol regulates insulin-degrading enzyme expression via an ERbeta/PI3-K pathway in hippocampus: relevance to Alzheimers prevention
Neurobiol. Aging
2011
32: 1949-1963
|
| 10213152 |
Kamboh MI et al.:
A novel mutation in the apolipoprotein E gene (APOE*4 Pittsburgh) is associated with the risk of late-onset Alzheimers disease
Neurosci. Lett.
1999
263: 129-132
|
| 20547867 |
Chen Y et al.:
ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 27103636 |
Sweet RA et al. et al.:
Apolipoprotein E*4 (APOE*4) Genotype Is Associated with Altered Levels of Glutamate Signaling Proteins and Synaptic Coexpression Networks in the Prefrontal Cortex in Mild to Moderate Alzheimer Disease
Mol. Cell Proteomics
2016
15: 2252-2262
|
| 10801051 |
Trioche P et al.:
Apolipoprotein E polymorphism and serum concentrations in patients with glycogen storage disease type Ia
J. Inherit. Metab. Dis.
2000
23: 107-112
|
| 2935594 |
author information missing
Loss of endoplasmic reticulum-associated enzymes in affected brain regions in Huntingtons disease and Alzheimer-type dementia
J. Neurol. Sci.
1985
71: 137-143
|
| 27392855 |
Bangen KJ et al.:
Interaction Between Midlife Blood Glucose and APOE Genotype Predicts Later Alzheimers Disease Pathology
J. Alzheimers Dis.
2016
53: 1553-1562
|
| 27328687 |
Yamazaki Y et al.:
Apolipoprotein E as a Therapeutic Target in Alzheimers Disease: A Review of Basic Research and Clinical Evidence
CNS Drugs
2016
30: 773-789
|
| 29946028 |
Prasad H et al.:
Amyloid clearance defect in ApoE4 astrocytes is reversed by epigenetic correction of endosomal pH
Proc. Natl. Acad. Sci. U.S.A.
2018
115
|
| 25561733 |
Prasad H et al.:
The Na+/H+ exchanger NHE6 modulates endosomal pH to control processing of amyloid precursor protein in a cell culture model of Alzheimer disease
J. Biol. Chem.
2015
290: 5311-5327
|
| 30337151 |
MahmoudianDehkordi S et al. et al.:
Altered bile acid profile associates with cognitive impairment in Alzheimers disease-An emerging role for gut microbiome
|
| 23340677 |
Schousboe A et al.:
Glutamate metabolism in the brain focusing on astrocytes
Adv Neurobiol
2014
11: 13-30
|
| 27740595 |
Hawkins RA et al.:
How Glutamate Is Managed by the Blood-Brain Barrier
|
| 29476033 |
Ekblad LL et al.:
Midlife insulin resistance, APOE genotype, and late-life brain amyloid accumulation
Neurology
2018
90
|
| 20452985 |
Munter LM et al.:
Aberrant amyloid precursor protein (APP) processing in hereditary forms of Alzheimer disease caused by APP familial Alzheimer disease mutations can be rescued by mutations in the APP GxxxG motif
J. Biol. Chem.
2010
285
|
| 26402005 |
Keeney JT et al.:
Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimers Disease Prevention and Early Intervention
J. Alzheimers Dis.
2015
48: 411-424
|
| 30032423 |
Uddin MS et al.:
APOE and Alzheimers Disease: Evidence Mounts that Targeting APOE4 may Combat Alzheimers Pathogenesis
Mol. Neurobiol.
2019
56: 2450-2465
|
| 30134963 |
Yi D et al.:
Synergistic interaction between APOE and family history of Alzheimers disease on cerebral amyloid deposition and glucose metabolism
Alzheimers Res Ther
2018
10: 84
|
| 28934977 |
Chhibber A et al.:
ERbeta and ApoE isoforms interact to regulate BDNF-5-HT2A signaling and synaptic function in the female brain
Alzheimers Res Ther
2017
9: 79
|
| 28272510 |
Johnson LA et al.:
Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome
Sci Rep
2017
7: 43701
|
| 28434655 |
Zhao N et al.:
Apolipoprotein E, Receptors, and Modulation of Alzheimers Disease
Biol. Psychiatry
2018
83: 347-357
|
| 29967007 |
Wu L et al.:
Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimers Disease Risk Reduction and Early Intervention
J. Neurosci.
2018
38: 6665-6681
|
| 14966149 |
Mosconi L et al.:
Brain metabolic decreases related to the dose of the ApoE e4 allele in Alzheimers disease
J. Neurol. Neurosurg. Psychiatry
2004
75: 370-376
|
| 30337152 |
Nho K et al. et al.:
Altered bile acid profile in mild cognitive impairment and Alzheimers disease: Relationship to neuroimaging and CSF biomarkers
Alzheimers Dement
2019
15: 232-244
|
| 30441866 |
Giau VV et al.:
Gut Microbiota and Their Neuroinflammatory Implications in Alzheimers Disease
|
| 30182854 |
Junges VM et al.:
Crosstalk between Gut Microbiota and Central Nervous System: A Focus on Alzheimers Disease
Curr Alzheimer Res
2018
15: 1179-1190
|
| 27604604 |
Kohler CA et al.:
The Gut-Brain Axis, Including the Microbiome, Leaky Gut and Bacterial Translocation: Mechanisms and Pathophysiological Role in Alzheimers Disease
Curr. Pharm. Des.
2016
22: 6152-6166
|
| 28937600 |
Del Rio D et al.:
The Gut Microbial Metabolite Trimethylamine-N-Oxide Is Present in Human Cerebrospinal Fluid
|
| 30138667 |
de J R De-Paula V et al.:
Relevance of gutmicrobiota in cognition, behaviour and Alzheimers disease
Pharmacol. Res.
2018
136: 29-34
|
| 27255810 |
Ciavardelli D et al.:
Medium-chain plasma acylcarnitines, ketone levels, cognition, and gray matter volumes in healthy elderly, mildly cognitively impaired, or Alzheimers disease subjects
Neurobiol. Aging
2016
43: 1-12
|
| 27566465 |
Hu X et al.:
Alzheimers disease and gut microbiota
Sci China Life Sci
2016
59: 1006-1023
|
| 22392034 |
Wang CC et al.:
The role of PGC-1 and Apoepsilon4 in insomnia
Psychiatr. Genet.
2012
22: 82-87
|
| 19749434 |
Cimini A et al.:
Early biochemical and morphological modifications in the brain of a transgenic mouse model of Alzheimers disease: a role for peroxisomes
J. Alzheimers Dis.
2009
18: 935-952
|
| 29758946 |
Zhuang ZQ et al. et al.:
Gut Microbiota is Altered in Patients with Alzheimers Disease
J. Alzheimers Dis.
2018
63: 1337-1346
|
| 28461186 |
Fan YY et al.:
APOE epsilon4 allele elevates the expressions of inflammatory factors and promotes Alzheimers disease progression: A comparative study based on Han and She populations in the Wenzhou area
Brain Res. Bull.
2017
132: 39-43
|
| 24990149 |
Guedes JR et al.:
Early miR-155 upregulation contributes to neuroinflammation in Alzheimers disease triple transgenic mouse model
Hum. Mol. Genet.
2014
23: 6286-6301
|
| 21377451 |
Zhou J et al.:
Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimers disease
Brain Res.
2011
1388: 141-147
|
| 29627302 |
Zhao H et al.:
Inhibitive Effect of Resveratrol on the Inflammation in Cultured Astrocytes and Microglia Induced by Abeta1-42
Neuroscience
2018
379: 390-404
|
| 24145446 |
Theendakara V et al. et al.:
Neuroprotective Sirtuin ratio reversed by ApoE4
Proc. Natl. Acad. Sci. U.S.A.
2013
110
|
| 29575030 |
Bauerl C et al.:
Shifts in gut microbiota composition in an APP/PSS1 transgenic mouse model of Alzheimers disease during lifespan
Lett. Appl. Microbiol.
2018
66: 464-471
|
| 29051531 |
Vogt NM et al.:
Gut microbiome alterations in Alzheimers disease
Sci Rep
2017
7: 13537
|
| 19631758 |
Reiman EM et al.:
Higher serum total cholesterol levels in late middle age are associated with glucose hypometabolism in brain regions affected by Alzheimers disease and normal aging
Neuroimage
2010
49: 169-176
|
| 28982335 |
Metaxas A et al.:
Reduced Serotonin Transporter Levels and Inflammation in the Midbrain Raphe of 12 Month Old APPswe/PSEN1dE9 Mice
Curr Alzheimer Res
2018
15: 420-428
|
| 18322398 |
Counts SE et al.:
Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimers disease
Neurodegener Dis
2008
5: 228-231
|
| 26592823 |
Zhang B et al.:
MiR-16 regulates cell death in Alzheimers disease by targeting amyloid precursor protein
Eur Rev Med Pharmacol Sci
2015
19: 4020-4027
|
| 26449188 |
Yun HM et al.:
Serotonin 6 receptor controls Alzheimers disease and depression
Oncotarget
2015
6
|
| 29703883 |
Kitzlerova E et al.:
Interactions Among Polymorphisms of Susceptibility Loci for Alzheimers Disease or Depressive Disorder
Med. Sci. Monit.
2018
24: 2599-2619
|
| 21926624 |
Enache D et al.:
Depression in dementia: epidemiology, mechanisms, and treatment
Curr Opin Psychiatry
2011
24: 461-472
|
| 12052537 |
Emilsson L et al.:
Increased monoamine oxidase messenger RNA expression levels in frontal cortex of Alzheimers disease patients
Neurosci. Lett.
2002
326: 56-60
|
| 12098640 |
Takehashi M et al.:
Association of monoamine oxidase A gene polymorphism with Alzheimers disease and Lewy body variant
Neurosci. Lett.
2002
327: 79-82
|
| 17692293 |
Wu YH et al.:
A promoter polymorphism in the monoamine oxidase A gene is associated with the pineal MAOA activity in Alzheimers disease patients
Brain Res.
2007
1167: 13-19
|
| 30692905 |
Forny-Germano L et al.:
The Role of Leptin and Adiponectin in Obesity-Associated Cognitive Decline and Alzheimers Disease
Front Neurosci
2019
12: 1027
|
| 29929471 |
Chang YS et al.:
Higher levels of thyroxine may predict a favorable response to donepezil treatment in patients with Alzheimer disease: a prospective, case-control study
BMC Neurosci
2018
19: 36
|
| 11155096 |
Kalmijn S et al.:
Subclinical hyperthyroidism and the risk of dementia. The Rotterdam study
Clin. Endocrinol. (Oxf)
2000
53: 733-737
|
| 28124751 |
Farbood Y et al.:
Peripheral and central administration of T3 improved the histological changes, memory and the dentate gyrus electrophysiological activity in an animal model of Alzheimers disease
Metab Brain Dis
2017
32: 693-701
|
| 29481662 |
McAninch EA et al.:
A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans
J. Clin. Endocrinol. Metab.
2018
103: 1818-1826
|
| 17105838 |
de Jong FJ et al.:
The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe
J. Clin. Endocrinol. Metab.
2007
92: 636-640
|
| 25735998 |
Wang T et al.:
TNF-alpha G308A polymorphism and the susceptibility to Alzheimers disease: an updated meta-analysis
Arch. Med. Res.
2015
46: 24-30.e1
|
| 28294066 |
Shukla M et al.:
Mechanisms of Melatonin in Alleviating Alzheimers Disease
Curr Neuropharmacol
2017
15: 1010-1031
|
| 29774516 |
Fu X et al.:
Periodic Variation of AAK1 in an Abeta1-42-Induced Mouse Model of Alzheimers Disease
J. Mol. Neurosci.
2018
65: 179-189
|
| 29376091 |
Kjeldsen EW et al.:
ABCA7 and risk of dementia and vascular disease in the Danish population
Ann Clin Transl Neurol
2017
5: 41-51
|
| 25594074 |
Rohn TT et al.:
Is Apolipoprotein E4 an Important Risk Factor for Dementia in Persons with Down Syndrome?
|
| 20946940 |
Patel A et al.:
Association of variants within APOE, SORL1, RUNX1, BACE1 and ALDH18A1 with dementia in Alzheimers disease in subjects with Down syndrome
Neurosci. Lett.
2011
487: 144-148
|
| 21098978 |
Sherva R et al.:
Identification of novel candidate genes for Alzheimers disease by autozygosity mapping using genome wide SNP data
J Alzheimers Dis
2011
23: 349-359
|
| 30898171 |
Smith AR et al.:
Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimers disease
Clin Epigenetics
2019
11: 52
|
| 17687027 |
Romito-DiGiacomo RR et al.:
Effects of Alzheimers disease on different cortical layers: the role of intrinsic differences in Abeta susceptibility
J. Neurosci.
2007
27: 8496-8504
|
| 31618972 |
Psemeneckiene G et al.:
Polymorphisms of Proinflammatory Cytokines in Relation to APOE Epsilon 4 and Risk of Alzheimers Disease in the Lithuanian Population
|
| 24671632 |
Chin D et al.:
Adenosine triphosphate concentrations are higher in the brain of APOE3- compared to APOE4-targeted replacement mice and can be modulated by curcumin
Genes Nutr
2014
9: 397
|
| 26564908 |
Tambini MD et al.:
ApoE4 upregulates the activity of mitochondria-associated ER membranes
EMBO Rep.
2016
17: 27-36
|
| 22730380 |
Cash JG et al.:
Apolipoprotein E4 impairs macrophage efferocytosis and potentiates apoptosis by accelerating endoplasmic reticulum stress
J. Biol. Chem.
2012
287
|
| 28333036 |
Abdullah L et al.:
APOE epsilon4 specific imbalance of arachidonic acid and docosahexaenoic acid in serum phospholipids identifies individuals with preclinical Mild Cognitive Impairment/Alzheimers Disease
Aging (Albany NY)
2017
9: 964-985
|
| 30804776 |
Fernandez CG et al.:
The Role of APOE4 in Disrupting the Homeostatic Functions of Astrocytes and Microglia in Aging and Alzheimers Disease
Front Aging Neurosci
2019
11: 14
|
| 26993346 |
Schott JM et al. et al.:
Genetic risk factors for the posterior cortical atrophy variant of Alzheimers disease
Alzheimers Dement
2016
12: 862-871
|
| 26374899 |
Atagi Y et al. et al.:
Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
J. Biol. Chem.
2015
290
|
| 24386905 |
Tai LM et al.:
Soluble apoE/Abeta complex: mechanism and therapeutic target for APOE4-induced AD risk
Mol Neurodegener
2014
9: 2
|
| 30127720 |
Konishi H et al.:
Microglial TREM2/DAP12 Signaling: A Double-Edged Sword in Neural Diseases
Front Cell Neurosci
2018
12: 206
|
| 28164773 |
Shackleton B et al.:
Apolipoprotein E-mediated Modulation of ADAM10 in Alzheimers Disease
Curr Alzheimer Res
2017
14: 578-585
|
| 30836275 |
Manzine PR et al.:
ADAM10 in Alzheimers disease: Pharmacological modulation by natural compounds and its role as a peripheral marker
Biomed. Pharmacother.
2019
113
|
| 31980586 |
Meilandt WJ et al. et al.:
Trem2 deletion reduces late-stage amyloid plaque accumulation, elevates the Abeta42:Abeta40 ratio, and exacerbates axonal dystrophy and dendritic spine loss in the PS2APP Alzheimers mouse model
|
| 28930663 |
Krasemann S et al. et al.:
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
Immunity
2017
47: 566-581.e9
|
| 31130847 |
Muth C et al.:
Phagocytosis of Apoptotic Cells Is Specifically Upregulated in ApoE4 Expressing Microglia in vitro
Front Cell Neurosci
2019
13: 181
|
| 30038567 |
Zhou Y et al.:
TREM2-Dependent Effects on Microglia in Alzheimers Disease
Front Aging Neurosci
2018
10: 202
|
| 27239545 |
Guedes JR et al.:
MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimers disease
Alzheimers Dement (Amst)
2015
3: 7-17
|
| 25593125 |
Li X et al.:
Different mechanisms of apolipoprotein E isoform-dependent modulation of prostaglandin E2 production and triggering receptor expressed on myeloid cells 2 (TREM2) expression after innate immune activation of microglia
FASEB J.
2015
29: 1754-1762
|
| 27636840 |
Musunuri S et al.:
Increased Levels of Extracellular Microvesicle Markers and Decreased Levels of Endocytic/Exocytic Proteins in the Alzheimers Disease Brain
J. Alzheimers Dis.
2016
54: 1671-1686
|
| 31640095 |
Wong MWK et al.:
APOE Genotype Differentially Modulates Plasma Lipids in Healthy Older Individuals, with Relevance to Brain Health
J. Alzheimers Dis.
2019
72: 703-716
|
| 27087442 |
Zhou M et al. et al.:
APOE4 Induces Site-Specific Tau Phosphorylation Through Calpain-CDK5 Signaling Pathway in EFAD-Tg Mice
Curr Alzheimer Res
2016
13: 1048-1055
|
| 28959956 |
Shi Y et al. et al.:
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
Nature
2017
549: 523-527
|
| 30314521 |
Sierksma A et al.:
Deregulation of neuronal miRNAs induced by amyloid-beta or TAU pathology
Mol Neurodegener
2018
13: 54
|
| 32123170 |
Arnold M et al. et al.:
Sex and APOE epsilon4 genotype modify the Alzheimers disease serum metabolome
Nat Commun
2020
11: 1148
|
| 27457486 |
Dose J et al.:
APOE genotype and stress response - a mini review
Lipids Health Dis
2016
15: 121
|
| 29340569 |
Apostolova LG et al. et al.:
Associations of the Top 20 Alzheimer Disease Risk Variants With Brain Amyloidosis
JAMA Neurol
2018
75: 328-341
|
| 31848472 |
Luo J et al.:
Mechanisms and regulation of cholesterol homeostasis
|
| 30590907 |
Lee S et al.:
The Interface Between ER and Mitochondria: Molecular Compositions and Functions
Mol. Cells
2018
41: 1000-1007
|
| 27235807 |
Area-Gomez E et al.:
Mitochondria-associated ER membranes and Alzheimer disease
Curr. Opin. Genet. Dev.
2016
38: 90-96
|
| 26639975 |
Malishkevich A et al.:
Blood-Borne Activity-Dependent Neuroprotective Protein (ADNP) is Correlated with Premorbid Intelligence, Clinical Stage, and Alzheimers Disease Biomarkers
J. Alzheimers Dis.
2016
50: 249-260
|
| 22832961 |
Kamboh MI et al. et al.:
Genome-wide association study of Alzheimers disease
Transl Psychiatry
2012
2: e117
|
| 21786198 |
Chakroborty S et al.:
Early calcium dysregulation in Alzheimers disease: setting the stage for synaptic dysfunction
Sci China Life Sci
2011
54: 752-762
|
| 30883359 |
Orr AL et al.:
Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function
J. Alzheimers Dis.
2019
68: 991-1011
|
| 31052389 |
Suidan GL et al.:
Targeting Apolipoprotein E for Alzheimers Disease: An Industry Perspective
|
| 11447277 |
Huang Y et al.:
Apolipoprotein E fragments present in Alzheimers disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons
Proc. Natl. Acad. Sci. U.S.A.
2001
98: 8838-8843
|
| 16344479 |
Chang S et al.:
Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity
Proc. Natl. Acad. Sci. U.S.A.
2005
102
|
| 23867607 |
Rohn TT et al.:
Proteolytic cleavage of apolipoprotein E4 as the keystone for the heightened risk associated with Alzheimers disease
Int J Mol Sci
2013
14
|
| 19695092 |
Nakamura T et al.:
Apolipoprotein E4 (1-272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells
Mol Neurodegener
2009
4: 35
|
| 12939405 |
Harris FM et al. et al.:
Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimers disease-like neurodegeneration and behavioral deficits in transgenic mice
Proc. Natl. Acad. Sci. U.S.A.
2003
100
|
| 30028014 |
Chernick D et al.:
High-density lipoprotein mimetic peptide 4F mitigates amyloid-beta-induced inhibition of apolipoprotein E secretion and lipidation in primary astrocytes and microglia
J. Neurochem.
2018
147: 647-662
|
| 30444064 |
Stopnicki B et al.:
Helper CD4 T cells expressing granzyme B cause glial fibrillary acidic protein fragmentation in astrocytes in an MHCII-independent manner
Glia
2019
67: 582-593
|
| 8819138 |
Haug LS et al.:
Decreased inositol (1,4,5)-trisphosphate receptor levels in Alzheimers disease cerebral cortex: selectivity of changes and possible correlation to pathological severity
Neurodegeneration
1996
5: 169-176
|
| 29253316 |
Egorova PA et al.:
Inositol 1,4,5-trisphosphate receptors and neurodegenerative disorders
FEBS J.
2018
285: 3547-3565
|
| 18478527 |
Wojda U et al.:
Calcium ions in neuronal degeneration
IUBMB Life
2008
60: 575-590
|
| 26372964 |
Zhu L et al.:
Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimers disease pathogenesis
Proc. Natl. Acad. Sci. U.S.A.
2015
112
|
| 27277824 |
Mahley RW et al.:
Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders
J. Mol. Med.
2016
94: 739-746
|
| 31306119 |
Simonovitch S et al.:
The Effects of APOE4 on Mitochondrial Dynamics and Proteins in vivo
J. Alzheimers Dis.
2019
70: 861-875
|
| 1663746 |
Mattson MP et al.:
Effects of elevated intracellular calcium levels on the cytoskeleton and tau in cultured human cortical neurons
Mol. Chem. Neuropathol.
1991
15: 117-142
|
| 26213471 |
Giau VV et al.:
Role of apolipoprotein E in neurodegenerative diseases
Neuropsychiatr Dis Treat
2015
11: 1723-1737
|
| 28424375 |
Ventura-Clapier R et al.:
Mitochondria: a central target for sex differences in pathologies
Clin. Sci.
2017
131: 803-822
|
| 19075583 |
Muller T et al.:
Disease state, age, sex, and post-mortem time-dependent expression of proteins in AD vs. control frontal cortex brain samples
Curr Alzheimer Res
2008
5: 562-571
|
| 20157261 |
Mueller C et al.:
The heme degradation pathway is a promising serum biomarker source for the early detection of Alzheimers disease
J. Alzheimers Dis.
2010
19: 1081-1091
|
| 30890171 |
Safieh M et al.:
ApoE4: an emerging therapeutic target for Alzheimers disease
BMC Med
2019
17: 64
|
| 16369530 |
Rovelet-Lecrux A et al. et al.:
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy
Nat. Genet.
2006
38: 24-26
|
| 30507579 |
Reed MJ et al.:
Increased Hyaluronan and TSG-6 in Association with Neuropathologic Changes of Alzheimers Disease
J. Alzheimers Dis.
2019
67: 91-102
|
| 11053967 |
Savaskan E et al.:
Alterations in trk A, trk B and trk C receptor immunoreactivities in parietal cortex and cerebellum in Alzheimers disease
Eur. Neurol.
2000
44: 172-180
|
| 17564960 |
Liu F et al. et al.:
A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population
Am. J. Hum. Genet.
2007
81: 17-31
|
| 20858966 |
Gahete MD et al.:
Expression of the ghrelin and neurotensin systems is altered in the temporal lobe of Alzheimers disease patients
J. Alzheimers Dis.
2010
22: 819-828
|
| 21681798 |
Hata S et al. et al.:
Alternative processing of gamma-secretase substrates in common forms of mild cognitive impairment and Alzheimers disease: evidence for gamma-secretase dysfunction
Ann. Neurol.
2011
69: 1026-1031
|
| 26384575 |
Feher A et al.:
Genetic analysis of the RELN gene: Gender specific association with Alzheimers disease
Psychiatry Res
2015
230: 716-718
|
| 28821390 |
Ramakrishnan V et al.:
PSEN1 gene polymorphisms in Caucasian Alzheimers disease: A meta-analysis
Clin. Chim. Acta
2017
473: 65-70
|
| 29885764 |
Wachinger C et al.:
A Longitudinal Imaging Genetics Study of Neuroanatomical Asymmetry in Alzheimers Disease
Biol. Psychiatry
2018
84: 522-530
|
| 31068785 |
Brooks LRK et al.:
Data-Driven Analysis of Age, Sex, and Tissue Effects on Gene Expression Variability in Alzheimers Disease
Front Neurosci
2019
13: 392
|
| 32160551 |
Yasukawa T et al.:
NRBP1-Containing CRL2/CRL4A Regulates Amyloid beta Production by Targeting BRI2 and BRI3 for Degradation
Cell Rep
2020
30: 3478-3491.e6
|
| 30480246 |
Dolfe L et al. et al.:
The Bri2 and Bri3 BRICHOS Domains Interact Differently with Abeta42 and Alzheimer Amyloid Plaques
J Alzheimers Dis Rep
2018
2: 27-39
|
| 19874264 |
Zhong N et al.:
Understanding the basis for the association of apoE4 with Alzheimers disease: opening the door for therapeutic approaches
Curr Alzheimer Res
2009
6: 415-418
|
| 15312168 |
Irizarry MC et al.:
Apolipoprotein E modulates gamma-secretase cleavage of the amyloid precursor protein
J. Neurochem.
2004
90: 1132-1143
|
| 9067471 |
Ishii K et al. et al.:
Abeta1-40 but not Abeta1-42 levels in cortex correlate with apolipoprotein E epsilon4 allele dosage in sporadic Alzheimers disease
Brain Res.
1997
748: 250-252
|
| 8602762 |
Gearing M et al.:
Abeta-peptide length and apolipoprotein E genotype in Alzheimers disease
Ann. Neurol.
1996
39: 395-399
|
| 27884212 |
Kehoe PG et al.:
Angiotensin-converting enzyme 2 is reduced in Alzheimers disease in association with increasing amyloid-beta and tau pathology
Alzheimers Res Ther
2016
8: 50
|
| 29196815 |
Mroczko B et al.:
Amyloid beta oligomers (AbetaOs) in Alzheimers disease
J Neural Transm (Vienna)
2018
125: 177-191
|
| 30541599 |
Kant S et al.:
Choroid plexus genes for CSF production and brain homeostasis are altered in Alzheimers disease
Fluids Barriers CNS
2018
15: 34
|
| 29755342 |
Lejri I et al.:
Mitochondria, Estrogen and Female Brain Aging
Front Aging Neurosci
2018
10: 124
|
| 25720398 |
Le Page A et al.:
NK Cells are Activated in Amnestic Mild Cognitive Impairment but not in Mild Alzheimers Disease Patients
J. Alzheimers Dis.
2015
46: 93-107
|
| 15225622 |
Yamamoto N et al.:
Accelerated Abeta aggregation in the presence of GM1-ganglioside-accumulated synaptosomes of aged apoE4-knock-in mouse brain
FEBS Lett.
2004
569: 135-139
|
| 29272008 |
Xu D et al.:
Apolipoprotein E 4 triggers multiple pathway-mediated Ca2+ overload, causes CaMK II phosphorylation abnormity and aggravates oxidative stress caused cerebral cortical neuron damage
Eur Rev Med Pharmacol Sci
2017
21: 5717-5728
|
| 27358062 |
Ayers KL et al.:
A loss of function variant in CASP7 protects against Alzheimers disease in homozygous APOE epsilon4 allele carriers
BMC Genomics
2016
17: Suppl 2 445
|
| 28985224 |
Rehker J et al. et al.:
Caspase-8, association with Alzheimers Disease and functional analysis of rare variants
PLoS ONE
2017
12
|
| 30850702 |
Mouchard A et al.:
ApoE-fragment/Abeta heteromers in the brain of patients with Alzheimers disease
Sci Rep
2019
9: 3989
|
| 18845536 |
Roychaudhuri R et al.:
Amyloid beta-protein assembly and Alzheimer disease
J. Biol. Chem.
2009
284: 4749-4753
|
| 23620513 |
Verghese PB et al.:
ApoE influences amyloid-beta (Abeta) clearance despite minimal apoE/Abeta association in physiological conditions
Proc. Natl. Acad. Sci. U.S.A.
2013
110
|
| 27470930 |
Salameh TS et al.:
Insulin resistance, dyslipidemia, and apolipoprotein E interactions as mechanisms in cognitive impairment and Alzheimers disease
Exp. Biol. Med. (Maywood)
2016
241: 1676-1683
|
| 30814349 |
Smith CJ et al.:
Putative Survival Advantages in Young Apolipoprotein varepsilon4 Carriers are Associated with Increased Neural Stress
J. Alzheimers Dis.
2019
68: 885-923
|
| 15220465 |
Corbo RM et al.:
Apolipoprotein E polymorphism and fertility: a study in pre-industrial populations
Mol. Hum. Reprod.
2004
10: 617-620
|
| 8698352 |
Gerdes LU et al.:
Are men carrying the apolipoprotein epsilon 4- or epsilon 2 allele less fertile than epsilon 3 epsilon 3 genotypes?
Hum. Genet.
1996
98: 239-242
|
| 28683096 |
van Exel E et al.:
Effect of APOE epsilon4 allele on survival and fertility in an adverse environment
PLoS ONE
2017
12
|
| 25282659 |
Gaynor JW et al. et al.:
Validation of association of the apolipoprotein E epsilon2 allele with neurodevelopmental dysfunction after cardiac surgery in neonates and infants
J. Thorac. Cardiovasc. Surg.
2014
148: 2560-2566
|
| 28335828 |
Yassine HN et al.:
DHA brain uptake and APOE4 status: a PET study with [1-(11)C]-DHA
Alzheimers Res Ther
2017
9: 23
|
| 21659554 |
Huebbe P et al.:
APOE epsilon4 is associated with higher vitamin D levels in targeted replacement mice and humans
FASEB J.
2011
25: 3262-3270
|
| 28284953 |
Stening E et al.:
Specific patterns of whole-brain structural covariance of the anterior and posterior hippocampus in young APOE epsilon4 carriers
Behav. Brain Res.
2017
326: 256-264
|
| 21606569 |
Alexopoulos P et al.:
Hippocampal volume differences between healthy young apolipoprotein E epsilon2 and epsilon4 carriers
J. Alzheimers Dis.
2011
26: 207-210
|
| 21215387 |
Taylor AE et al.:
IQ, educational attainment, memory and plasma lipids: associations with apolipoprotein E genotype in 5995 children
Biol. Psychiatry
2011
70: 152-158
|
| 8475230 |
Keltikangas-Jarvinen L et al.:
Dependence between apolipoprotein E phenotypes and temperament in children, adolescents, and young adults
Psychosom Med
1993
55: 155-163
|
| 19605830 |
Caselli RJ et al. et al.:
Longitudinal modeling of age-related memory decline and the APOE epsilon4 effect
N. Engl. J. Med.
2009
361: 255-263
|
| 17395708 |
Brown CM et al.:
Androgen-mediated immune function is altered by the apolipoprotein E gene
Endocrinology
2007
148: 3383-3390
|
| 24444806 |
Panizzon MS et al. et al.:
Interaction of APOE genotype and testosterone on episodic memory in middle-aged men
Neurobiol. Aging
2014
35: 1778.e1-1778.e8
|
| 26791201 |
Theendakara V et al.:
Direct Transcriptional Effects of Apolipoprotein E
J. Neurosci.
2016
36: 685-700
|
| 12077215 |
Raber J et al.:
Androgens protect against apolipoprotein E4-induced cognitive deficits
J. Neurosci.
2002
22: 5204-5209
|
| 28533891 |
Love JE et al.:
Nuclear uptake of an amino-terminal fragment of apolipoprotein E4 promotes cell death and localizes within microglia of the Alzheimers disease brain
Int J Physiol Pathophysiol Pharmacol
2017
9: 40-57
|
| 29264400 |
Rohn TT et al.:
Nuclear Localization of Apolipoprotein E4: A New Trick for an Old Protein
|
| 11305869 |
Cho HS et al.:
Quantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Abeta aggregation
J. Neuropathol. Exp. Neurol.
2001
60: 342-349
|
| 7715296 |
Wisniewski T et al.:
Is Alzheimers disease an apolipoprotein E amyloidosis?
Lancet
1995
345: 956-958
|
| 21368138 |
Bien-Ly N et al.:
C-terminal-truncated apolipoprotein (apo) E4 inefficiently clears amyloid-beta (Abeta) and acts in concert with Abeta to elicit neuronal and behavioral deficits in mice
Proc. Natl. Acad. Sci. U.S.A.
2011
108: 4236-4241
|
| 26402072 |
Duits FH et al.:
Matrix Metalloproteinases in Alzheimers Disease and Concurrent Cerebral Microbleeds
J. Alzheimers Dis.
2015
48: 711-720
|
| 25050378 |
Wang XX et al.:
Matrix metalloproteinases and their multiple roles in Alzheimers disease
Biomed Res Int
2014
2014
|
| 22445724 |
Dafnis I et al.:
An apolipoprotein E4 fragment affects matrix metalloproteinase 9, tissue inhibitor of metalloproteinase 1 and cytokine levels in brain cell lines
Neuroscience
2012
210: 21-32
|
| 16787929 |
Yan P et al. et al.:
Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ
J. Biol. Chem.
2006
281
|
| 20847401 |
Subramanian S et al.:
CCR6: a biomarker for Alzheimers-like disease in a triple transgenic mouse model
J. Alzheimers Dis.
2010
22: 619-629
|
| 12689599 |
Lorenzl S et al.:
Increased plasma levels of matrix metalloproteinase-9 in patients with Alzheimers disease
Neurochem. Int.
2003
43: 191-196
|
| 19235898 |
Hernandez-Guillamon M et al.:
Neuronal TIMP-1 release accompanies astrocytic MMP-9 secretion and enhances astrocyte proliferation induced by beta-amyloid 25-35 fragment
J. Neurosci. Res.
2009
87: 2115-2125
|
| 28094792 |
Urfer-Buchwalder A et al.:
Identification of a Nuclear Respiratory Factor 1 Recognition Motif in the Apolipoprotein E Variant APOE4 linked to Alzheimers Disease
Sci Rep
2017
7: 40668
|
| 22077634 |
Sheng B et al.:
Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimers disease
J. Neurochem.
2012
120: 419-429
|
| 28720530 |
Theendakara V et al.:
Downregulation of protein phosphatase 2A by apolipoprotein E: Implications for Alzheimers disease
Mol. Cell. Neurosci.
2017
83: 83-91
|
| 11796747 |
Casley CS et al.:
Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities
J. Neurochem.
2002
80: 91-100
|
| 32152337 |
Area-Gomez E et al. et al.:
APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice
Sci Rep
2020
10: 4277
|
| 29311783 |
Nuriel T et al.:
The Endosomal-Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo
Front Neurosci
2017
11: 702
|
| 10822435 |
Yaffe K et al.:
Estrogen use, APOE, and cognitive decline: evidence of gene-environment interaction
Neurology
2000
54: 1949-1954
|
| 9278514 |
Paech K et al.:
Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites
Science
1997
277: 1508-1510
|
| 22962256 |
Jayaraman A et al.:
17beta-estradiol and progesterone regulate expression of beta-amyloid clearance factors in primary neuron cultures and female rat brain
Endocrinology
2012
153: 5467-5479
|
| 15590928 |
Zhao L et al.:
Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimers disease intervention
J. Neurosci.
2004
24
|
| 25745640 |
Gottschalk WK et al.:
The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging
|
| 22514691 |
Cha MY et al.:
Mitochondria-specific accumulation of amyloid beta induces mitochondrial dysfunction leading to apoptotic cell death
PLoS ONE
2012
7
|
| 27636849 |
Sainaghi PP et al.:
Growth Arrest Specific 6 Concentration is Increased in the Cerebrospinal Fluid of Patients with Alzheimers Disease
J. Alzheimers Dis.
2017
55: 59-65
|
| 29433734 |
Santo EE et al.:
FOXO in Neural Cells and Diseases of the Nervous System
Curr. Top. Dev. Biol.
2018
127: 105-118
|
| 31808750 |
Yin J et al.:
Apolipoprotein E regulates mitochondrial function through the PGC-1alpha-sirtuin 3 pathway
Aging (Albany NY)
2019
11
|
| 19076441 |
Mosconi L et al.:
Brain glucose hypometabolism and oxidative stress in preclinical Alzheimers disease
Ann. N. Y. Acad. Sci.
2008
1147: 180-195
|
| 9596412 |
Montine KS et al.:
Distribution of reducible 4-hydroxynonenal adduct immunoreactivity in Alzheimer disease is associated with APOE genotype
J. Neuropathol. Exp. Neurol.
1998
57: 415-425
|
| 27583919 |
Zheng J et al.:
The CYP19A1 rs3751592 variant confers susceptibility to Alzheimer disease in the Chinese Han population
Medicine (Baltimore)
2016
95: e4742
|
| 20819998 |
Panizzon MS et al. et al.:
Testosterone modifies the effect of APOE genotype on hippocampal volume in middle-aged men
Neurology
2010
75: 874-880
|
| 18439297 |
Haasl RJ et al.:
A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimers disease in males carrying an apolipoprotein E epsilon4 allele
BMC Med. Genet.
2008
9: 37
|
| 19339974 |
Bu G et al.:
Apolipoprotein E and its receptors in Alzheimers disease: pathways, pathogenesis and therapy
Nat. Rev. Neurosci.
2009
10: 333-344
|
| 32521573 |
Han C et al.:
New mechanism of nerve injury in Alzheimers disease: beta-amyloid-induced neuronal pyroptosis
|
| 29028155 |
Brinkmalm G et al.:
A Parallel Reaction Monitoring Mass Spectrometric Method for Analysis of Potential CSF Biomarkers for Alzheimers Disease
|
| 32460813 |
Konijnenberg E et al. et al.:
APOE epsilon4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimers disease
Alzheimers Res Ther
2020
12: 65
|
| 27128370 |
Perkins M et al. et al.:
Altered Energy Metabolism Pathways in the Posterior Cingulate in Young Adult Apolipoprotein E varepsilon4 Carriers
J. Alzheimers Dis.
2016
53: 95-106
|
| 32973177 |
Valla J et al.:
Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE epsilon4 allele, the major late-onset Alzheimers susceptibility gene
J. Alzheimers Dis.
2010
22: 307-313
|
| 23639788 |
Djogo N et al.:
Adhesion molecule L1 binds to amyloid beta and reduces Alzheimers disease pathology in mice
Neurobiol. Dis.
2013
56: 104-115
|
| 10571241 |
Hiesberger T et al.:
Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation
Neuron
1999
24: 481-489
|
| 15014128 |
Brecht WJ et al.:
Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice
J. Neurosci.
2004
24: 2527-2534
|
| 32587511 |
Yassine HN et al.:
APOE Alleles and Diet in Brain Aging and Alzheimers Disease
Front Aging Neurosci
2020
12: 150
|
| 31738402 |
Seo DO et al.:
Gut Microbiota: From the Forgotten Organ to a Potential Key Player in the Pathology of Alzheimers Disease
J Gerontol A Biol Sci Med Sci
2020
75: 1232-1241
|
| 30958695 |
Tran TTT et al.:
APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimers disease pathophysiology
FASEB J
2019
33: 8221-8231
|
| 30336580 |
Griffin BA et al.:
APOE4 Genotype Exerts Greater Benefit in Lowering Plasma Cholesterol and Apolipoprotein B than Wild Type (E3/E3), after Replacement of Dietary Saturated Fats with Low Glycaemic Index Carbohydrates
|
| 23921897 |
Schonfeld P et al.:
Why does brain metabolism not favor burning of fatty acids to provide energy? Reflections on disadvantages of the use of free fatty acids as fuel for brain
J Cereb Blood Flow Metab
2013
33: 1493-1499
|
| 25488255 |
Wang SP et al.:
Metabolism as a tool for understanding human brain evolution: lipid energy metabolism as an example
J Hum Evol
2014
77: 41-49
|
| 22353463 |
Galea E et al.:
Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: a paradigm for multifactorial neurodegenerative diseases?
Biochim Biophys Acta
2012
1822: 1475-1488
|
| 32444841 |
Wang Y et al.:
Midlife Chronological and Endocrinological Transitions in Brain Metabolism: System Biology Basis for Increased Alzheimers Risk in Female Brain
Sci Rep
2020
10: 8528
|
| 11449190 |
Hogervorst E et al.:
Serum total testosterone is lower in men with Alzheimers disease
Neuro Endocrinol Lett
2001
22: 163-168
|
| 28655134 |
Asih PR et al.:
Multiple Mechanisms Linking Type 2 Diabetes and Alzheimers Disease: Testosterone as a Modifier
J Alzheimers Dis
2017
59: 445-466
|
| 32560743 |
Sundermann EE et al.:
Sex differences in Alzheimers-related Tau biomarkers and a mediating effect of testosterone
Biol Sex Differ
2020
11: 33
|
| 15750215 |
Steen E et al.:
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimers disease--is this type 3 diabetes?
J Alzheimers Dis
2005
7: 63-80
|
| 28438892 |
Camandola S et al.:
Brain metabolism in health, aging, and neurodegeneration
EMBO J
2017
36: 1474-1492
|
| 26669800 |
Shibuya Y et al.:
ACAT1/SOAT1 as a therapeutic target for Alzheimers disease
Future Med Chem
2015
7: 2451-2467
|
| 15269217 |
Wahrle SE et al.:
ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE
J Biol Chem
2004
279
|
| 15269218 |
Hirsch-Reinshagen V et al.:
Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain
J Biol Chem
2004
279
|
| 19326444 |
Minagawa H et al.:
Mechanism underlying apolipoprotein E (ApoE) isoform-dependent lipid efflux from neural cells in culture
J Neurosci Res
2009
87: 2498-2508
|
| 31813629 |
Bonfili L et al.:
Gut microbiota manipulation through probiotics oral administration restores glucose homeostasis in a mouse model of Alzheimers disease
Neurobiol Aging
2020
87: 35-43
|
| 32512571 |
author information missing
Involvement of testosterone signaling in the integrity of the neurovascular unit in the male: review of evidence, contradictions and hypothesis
|
| 9390772 |
Mooradian AD et al.:
GLUT-1 expression in the cerebra of patients with Alzheimers disease
Neurobiol Aging
1997
18: 469-474
|
| 31665905 |
Yamazaki Y et al.:
ApoE (Apolipoprotein E) in Brain Pericytes Regulates Endothelial Function in an Isoform-Dependent Manner by Modulating Basement Membrane Components
Arterioscler Thromb Vasc Biol
2020
40: 128-144
|
| 32376954 |
Montagne A et al. et al.:
APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline
Nature
2020
581: 71-76
|
| 32350425 |
author information missing
Risk factor for Alzheimers disease breaks the blood-brain barrier
Nature
2020
581: 31-32
|
| 24708805 |
Sajja RK et al.:
Impact of altered glycaemia on blood-brain barrier endothelium: an in vitro study using the hCMEC/D3 cell line
Fluids Barriers CNS
2014
11: 8
|
| 32789766 |
Koepsell H et al.:
Glucose transporters in brain in health and disease
Pflugers Arch
2020
472: 1299-1343
|
| 29797185 |
Raikwar SP et al.:
Are Tanycytes the Missing Link Between Type 2 Diabetes and Alzheimers Disease?
Mol Neurobiol
2019
56: 833-843
|
| 18174027 |
Liu Y et al.:
Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease
FEBS Lett
2008
582: 359-364
|
| 27372644 |
Salomon-Zimri S et al.:
Reversal of ApoE4-Driven Brain Pathology by Vascular Endothelial Growth Factor Treatment
J Alzheimers Dis
2016
53: 1443-1458
|
| 29401605 |
Wijesekara N et al.:
Tau ablation in mice leads to pancreatic beta cell dysfunction and glucose intolerance
FASEB J
2018
32: 3166-3173
|
| 28902142 |
Yamazaki Y et al.:
Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimers Disease
|
| 26195256 |
Tarasoff-Conway JM et al. et al.:
Clearance systems in the brain-implications for Alzheimer disease
Nat Rev Neurol
2015
11: 457-470
|
| 25921624 |
Yin F et al.:
The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity
Neurobiol Aging
2015
36: 2282-2295
|
| 24244584 |
Ding F et al.:
Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimers mouse brain: implication for bioenergetic intervention
PLoS One
2013
8
|
| 28984596 |
Palmieri G et al.:
Low Erythrocyte Levels of Proteasome and Acyl-Peptide Hydrolase (APEH) Activities in Alzheimers Disease: A Sign of Defective Proteostasis?
J Alzheimers Dis
2017
60: 1097-1106
|
| 19627603 |
Yamin R et al.:
Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide
Mol Neurodegener
2009
4: 33
|
| 24688718 |
Wakabayashi S et al.:
The essential biology of the endoplasmic reticulum stress response for structural and computational biologists
Comput Struct Biotechnol J
2013
6
|
| 20947216 |
Gleichmann M et al.:
Molecular changes in brain aging and Alzheimers disease are mirrored in experimentally silenced cortical neuron networks
Neurobiol Aging
2012
33: 205.e1-205.18
|
| 31382130 |
Wohua Z et al.:
Glutaredoxin 2 (GRX2) deficiency exacerbates high fat diet (HFD)-induced insulin resistance, inflammation and mitochondrial dysfunction in brain injury: A mechanism involving GSK-3beta
Biomed Pharmacother
2019
118
|
| 27154981 |
Yin F et al.:
Energy metabolism and inflammation in brain aging and Alzheimers disease
Free Radic Biol Med
2016
100: 108-122
|
| 31231219 |
Zuena AR et al.:
Chemokines in Alzheimers Disease: New Insights Into Prokineticins, Chemokine-Like Proteins
Front Pharmacol
2019
10: 622
|
| 19204726 |
Chapuis J et al. et al.:
Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimers disease
Mol Psychiatry
2009
14: 1004-1016
|
| 27091974 |
Fu AK et al.:
IL-33 ameliorates Alzheimers disease-like pathology and cognitive decline
Proc Natl Acad Sci U S A
2016
113
|
| 24413615 |
Xiong Z et al.:
Alzheimers disease: evidence for the expression of interleukin-33 and its receptor ST2 in the brain
J Alzheimers Dis
2014
40: 297-308
|
| 18571100 |
Pollio G et al. et al.:
Increased expression of the oligopeptidase THOP1 is a neuroprotective response to Abeta toxicity
Neurobiol Dis
2008
31: 145-158
|
| 12834896 |
Buddle M et al.:
Microtubule-associated protein 2 (MAP2) associates with the NMDA receptor and is spatially redistributed within rat hippocampal neurons after oxygen-glucose deprivation
Brain Res
2003
978: 38-50
|
| 17018137 |
Webber KM et al.:
Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease
Mol Neurodegener
2006
1: 14
|
| 22406427 |
Villanueva EB et al.:
Secreted phospholipase A(2) group IIA is a neurotoxin released by stimulated human glial cells
Mol Cell Neurosci
2012
49: 430-438
|
| 17764962 |
Parachikova A et al.:
Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease
Neurobiol Dis
2007
28: 143-153
|
| 30447377 |
Ye X et al.:
Association of CSF CD40 levels and synaptic degeneration across the Alzheimers disease spectrum
Neurosci Lett
2019
694: 41-45
|
| 27321472 |
Sun X et al.:
APOE epsilon4 carriers may undergo synaptic damage conferring risk of Alzheimers disease
Alzheimers Dement
2016
12: 1159-1166
|
| 23954108 |
Ebbert MT et al.:
Population-based analysis of Alzheimers disease risk alleles implicates genetic interactions
Biol Psychiatry
2014
75: 732-737
|
| 10574372 |
Tanahashi H et al.:
Genomic organization of the human X11L2 gene (APBA3), a third member of the X11 protein family interacting with Alzheimers beta-amyloid precursor protein
Neuroreport
1999
10: 2575-2578
|
| 19118172 |
Ho A et al.:
Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimers disease
J Neurosci
2008
28
|
| 29962946 |
Brandon JA et al.:
APOE and Alzheimers Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction
Front Aging Neurosci
2018
10: 180
|
| 29523845 |
Annese A et al.:
Whole transcriptome profiling of Late-Onset Alzheimers Disease patients provides insights into the molecular changes involved in the disease
Sci Rep
2018
8: 4282
|
| 27816213 |
Pichler S et al.:
The miRNome of Alzheimers disease: consistent downregulation of the miR-132/212 cluster
Neurobiol Aging
2017
50: 167.e1-167.e10
|
| 32075102 |
Pajuelo Reguera D et al.:
Cytochrome c Oxidase Subunit 4 Isoform Exchange Results in Modulation of Oxygen Affinity
|
| 16943564 |
Devi L et al.:
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimers disease brain is associated with mitochondrial dysfunction
J Neurosci
2006
26: 9057-9068
|
| 33086624 |
Murakami M et al.:
Updating Phospholipase A2 Biology
|
| 17965832 |
Wang Y et al.:
Trypsin and trypsin-like proteases in the brain: proteolysis and cellular functions
Cell Mol Life Sci
2008
65: 237-252
|
| 30394676 |
Sun LL et al.:
Molecular differences in Alzheimers disease between male and female patients determined by integrative network analysis
J Cell Mol Med
2019
23: 47-58
|
| 27983596 |
Preciados M et al.:
Estrogenic Endocrine Disrupting Chemicals Influencing NRF1 Regulated Gene Networks in the Development of Complex Human Brain Diseases
|
| 15932949 |
Reiman EM et al.:
Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism
Proc Natl Acad Sci U S A
2005
102: 8299-8302
|
| 31127273 |
Choi I et al.:
SIRT1 in Astrocytes Regulates Glucose Metabolism and Reproductive Function
Endocrinology
2019
160: 1547-1560
|
| 28768174 |
Goyal MS et al.:
Loss of Brain Aerobic Glycolysis in Normal Human Aging
Cell Metab
2017
26: 353-360.e3
|
| 16449386 |
Cai D et al.:
Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation
Proc Natl Acad Sci U S A
2006
103: 1941-1946
|
| 16449385 |
Cai D et al.:
Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimers disease-linked presenilin-1 mutant neurons
Proc Natl Acad Sci U S A
2006
103: 1936-1940
|
| 19276086 |
Liu Y et al.:
Intracellular trafficking of presenilin 1 is regulated by beta-amyloid precursor protein and phospholipase D1
J Biol Chem
2009
284
|
| 30918495 |
Camacho J et al.:
Brain ApoA-I, ApoJ and ApoE Immunodetection in Cerebral Amyloid Angiopathy
Front Neurol
2019
10: 187
|
| 31738162 |
Herring SK et al.:
Brain clusterin protein isoforms and mitochondrial localization
|
| 26682220 |
Ma C et al.:
Serum Levels of ApoA1 and ApoA2 Are Associated with Cognitive Status in Older Men
Biomed Res Int
2015
2015
|
| 24731980 |
Bai Z et al. et al.:
Distinctive RNA expression profiles in blood associated with Alzheimer disease after accounting for white matter hyperintensities
Alzheimer Dis Assoc Disord
2014
28: 226-233
|
| 20395015 |
Wikgren M et al.:
APOE epsilon4 is associated with longer telomeres, and longer telomeres among epsilon4 carriers predicts worse episodic memory
Neurobiol Aging
2012
33: 335-344
|
| 33891334 |
Pontifex MG et al.:
APOE4 genotype exacerbates the impact of menopause on cognition and synaptic plasticity in APOE-TR mice
FASEB J
2021
35
|
| 30540774 |
Mosconi L et al.:
Increased Alzheimers risk during the menopause transition: A 3-year longitudinal brain imaging study
PLoS One
2018
13
|
| 22016362 |
Takata Y et al.:
Association between ApoE phenotypes and telomere erosion in Alzheimers disease
J Gerontol A Biol Sci Med Sci
2012
67: 330-335
|
| 31890852 |
Mahoney ER et al.:
Telomere length associations with cognition depend on Alzheimers disease biomarkers
Alzheimers Dement (N Y)
2019
5: 883-890
|
| 17785354 |
Rao P et al.:
Angiotensin II regulates adipocyte apolipoprotein E expression
J Clin Endocrinol Metab
2007
92: 4366-4372
|
| 22825311 |
Honig LS et al.:
Association of shorter leukocyte telomere repeat length with dementia and mortality
Arch Neurol
2012
69: 1332-1339
|
| 24241262 |
author information missing
Apolipoprotein E4 prevents growth of malaria at the intraerythrocyte stage: implications for differences in racial susceptibility to Alzheimers disease
J Health Care Poor Underserved
2013
24: 70-78
|
| 21686130 |
Culpan D et al.:
Tumour necrosis factor-alpha (TNF-alpha) and miRNA expression in frontal and temporal neocortex in Alzheimers disease and the effect of TNF-alpha on miRNA expression in vitro
Int J Mol Epidemiol Genet
2011
2: 156-162
|
| 28894825 |
Thomson RS et al.:
Hearing loss as a risk factor for dementia: A systematic review
Laryngoscope Investig Otolaryngol
2017
2: 69-79
|
| 31984308 |
An YA et al. et al.:
Dysregulation of Amyloid Precursor Protein Impairs Adipose Tissue Mitochondrial Function and Promotes Obesity
Nat Metab
2019
1: 1243-1257
|
| 32630431 |
Chaudhari K et al.:
ApoE Genotype-Dependent Response to Antioxidant and Exercise Interventions on Brain Function
|
| 18179727 |
Jofre-Monseny L et al.:
Influence of apolipoprotein E genotype and dietary alpha-tocopherol on redox status and C-reactive protein levels in apolipoprotein E3 and E4 targeted replacement mice
Br J Nutr
2008
100: 44-53
|
| 10490274 |
Ramassamy C et al.:
Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimers disease is related to the apolipoprotein E genotype
Free Radic Biol Med
1999
27: 544-553
|
| 28035917 |
Persson T et al.:
Apolipoprotein E4 Elicits Lysosomal Cathepsin D Release, Decreased Thioredoxin-1 Levels, and Apoptosis
J Alzheimers Dis
2017
56: 601-617
|
| 26924205 |
Wang Y et al.:
Lost region in amyloid precursor protein (APP) through TALEN-mediated genome editing alters mitochondrial morphology
Sci Rep
2016
6: 22244
|
| 25335802 |
Alata W et al.:
Human apolipoprotein E varepsilon4 expression impairs cerebral vascularization and blood-brain barrier function in mice
J Cereb Blood Flow Metab
2015
35: 86-94
|
| 30232327 |
Koizumi K et al. et al.:
Apoepsilon4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function
Nat Commun
2018
9: 3816
|
| 8179300 |
Simpson IA et al.:
Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimers disease
Ann Neurol
1994
35: 546-551
|
| 12325053 |
Hogervorst E et al.:
Apolipoprotein E epsilon4 and testosterone interact in the risk of Alzheimers disease in men
Int J Geriatr Psychiatry
2002
17: 938-940
|
| 10573435 |
Barrett-Connor E et al.:
Cognitive function and endogenous sex hormones in older women
J Am Geriatr Soc
1999
47: 1289-1293
|
| 22596268 |
Hedskog L et al.:
Biochemical studies of poly-T variants in the Alzheimers disease associated TOMM40 gene
J Alzheimers Dis
2012
31: 527-536
|
| 2769254 |
Kalaria RN et al.:
Reduced glucose transporter at the blood-brain barrier and in cerebral cortex in Alzheimer disease
J Neurochem
1989
53: 1083-1088
|
| 7815078 |
Harr SD et al.:
Functional alterations in Alzheimers disease: decreased glucose transporter 3 immunoreactivity in the perforant pathway terminal zone
J Neuropathol Exp Neurol
1995
54: 38-41
|
| 2514687 |
Tanaka S et al.:
Tissue-specific expression of three types of beta-protein precursor mRNA: enhancement of protease inhibitor-harboring types in Alzheimers disease brain
Biochem Biophys Res Commun
1989
165: 1406-1414
|
| 14992810 |
Preece P et al.:
Amyloid precursor protein mRNA levels in Alzheimers disease brain
Brain Res Mol Brain Res
2004
122: 1-9
|
| 22089642 |
Bekris LM et al.:
Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE
J Hum Genet
2012
57: 18-25
|
| 34157306 |
author information missing
article information missing
|
| 32471464 |
author information missing
article information missing
|
| 32296178 |
author information missing
article information missing
|
| 27604972 |
author information missing
article information missing
|
| 21705112 |
author information missing
article information missing
|
| 29353455 |
author information missing
article information missing
|
| 26590417 |
author information missing
article information missing
|
| 20847408 |
author information missing
article information missing
|
| 32973177 |
author information missing
article information missing
|
| 29423459 |
author information missing
article information missing
|
| 25869786 |
author information missing
article information missing
|
| 15033273 |
author information missing
article information missing
|
| 31760549 |
author information missing
article information missing
|
| 30394676 |
author information missing
article information missing
|
| 33340485 |
author information missing
article information missing
|
| 33580390 |
author information missing
article information missing
|
| 12214001 |
author information missing
article information missing
|
| 34489623 |
author information missing
article information missing
|
| 33410232 |
author information missing
article information missing
|
| 33723589 |
author information missing
article information missing
|
| 32070225 |
author information missing
article information missing
|
| 32161412 |
author information missing
article information missing
|
| 32397599 |
author information missing
article information missing
|
| 24067654 |
author information missing
article information missing
|
| 33027662 |
author information missing
article information missing
|
| 31738978 |
author information missing
article information missing
|
| 10462693 |
author information missing
article information missing
|
| 21316350 |
author information missing
article information missing
|
| 18657529 |
author information missing
article information missing
|
| 31677348 |
author information missing
article information missing
|
| 31164996 |
author information missing
article information missing
|
| 33500712 |
author information missing
article information missing
|
| 15358178 |
author information missing
article information missing
|
| 15627653 |
author information missing
article information missing
|
| 34064758 |
author information missing
article information missing
|
| 17868329 |
author information missing
article information missing
|
| 22863908 |
author information missing
article information missing
|
| 23792692 |
author information missing
article information missing
|
| 33676568 |
author information missing
article information missing
|
| 31711277 |
author information missing
article information missing
|
| 28096339 |
author information missing
article information missing
|
| 31257151 |
author information missing
article information missing
|
| 24276092 |
author information missing
article information missing
|
| 31641056 |
author information missing
article information missing
|
| 34616039 |
author information missing
article information missing
|
| 34647685 |
author information missing
article information missing
|
| 33180216 |
author information missing
article information missing
|
| 35163221 |
author information missing
article information missing
|
| 35669462 |
author information missing
article information missing
|
| 24149440 |
author information missing
article information missing
|
| 35291561 |
author information missing
article information missing
|
| 32044129 |
author information missing
article information missing
|
| 26844268 |
author information missing
article information missing
|
| 32866617 |
author information missing
article information missing
|
| 32709881 |
author information missing
article information missing
|
| 11359882 |
author information missing
article information missing
|
| 32917959 |
author information missing
article information missing
|
| 31130380 |
author information missing
article information missing
|
| 35346689 |
author information missing
article information missing
|
| 35088039 |
author information missing
article information missing
|
| 34439479 |
author information missing
article information missing
|
| 32338825 |
author information missing
article information missing
|
| 26686055 |
author information missing
article information missing
|
| 33400183 |
author information missing
article information missing
|
| 33378713 |
author information missing
article information missing
|
| 31951107 |
author information missing
article information missing
|
| 32210766 |
author information missing
article information missing
|
| 21594711 |
author information missing
article information missing
|
| 34465385 |
author information missing
article information missing
|
| 33958804 |
author information missing
article information missing
|
| 35644025 |
author information missing
article information missing
|
| 22046147 |
author information missing
article information missing
|
| 19368807 |
author information missing
article information missing
|
| 11804574 |
author information missing
article information missing
|
| 8480510 |
author information missing
article information missing
|
| 16996687 |
author information missing
article information missing
|
| 21244353 |
author information missing
article information missing
|
| 8987775 |
author information missing
article information missing
|
| 23408593 |
author information missing
article information missing
|
| 9547230 |
author information missing
article information missing
|
| 10359075 |
author information missing
article information missing
|
| 24594013 |
author information missing
article information missing
|
| 34639003 |
author information missing
article information missing
|
| 28458525 |
author information missing
article information missing
|
| 20644562 |
author information missing
article information missing
|
| 31601022 |
author information missing
article information missing
|
| 30385318 |
author information missing
article information missing
|
| 3585324 |
author information missing
article information missing
|
| 16574032 |
author information missing
article information missing
|
| 8421706 |
author information missing
article information missing
|
| 21799757 |
author information missing
article information missing
|
| 34943074 |
author information missing
article information missing
|
| 23679855 |
author information missing
article information missing
|
| 24275950 |
author information missing
article information missing
|
| 34044147 |
author information missing
article information missing
|
| 34749800 |
author information missing
article information missing
|
| 26405162 |
author information missing
article information missing
|
| 27254664 |
author information missing
article information missing
|
| 30781626 |
author information missing
article information missing
|
| 14527403 |
author information missing
article information missing
|
| 37470054 |
author information missing
article information missing
|
| 17635647 |
author information missing
article information missing
|
| 33265993 |
author information missing
article information missing
|
| 22733998 |
author information missing
article information missing
|
| 30770921 |
author information missing
article information missing
|
| 38774266 |
author information missing
article information missing
|
| 23197718 |
author information missing
article information missing
|
| 35301433 |
author information missing
article information missing
|
| 26578886 |
author information missing
article information missing
|
| 34112773 |
author information missing
article information missing
|
| 36343267 |
author information missing
article information missing
|
| 31964863 |
author information missing
article information missing
|
| 37700846 |
author information missing
article information missing
|
| 23898460 |
author information missing
article information missing
|
| 19176370 |
Catalano A et al.:
The plexin-A1 receptor activates vascular endothelial growth factor-receptor 2 and nuclear factor-kappaB to mediate survival and anchorage-independent growth of malignant mesothelioma cells
Cancer Res.
2009
69: 1485-1493
|
| 19176370 |
Catalano A et al.:
The plexin-A1 receptor activates vascular endothelial growth factor-receptor 2 and nuclear factor-kappaB to mediate survival and anchorage-independent growth of malignant mesothelioma cells.
Cancer Res.
2009
69: 1485-1493
|
| 19176370 |
Catalano A et al.:
The plexin-A1 receptor activates vascular endothelial growth factor-receptor 2 and nuclear factor-kappaB to mediate survival and anchorage-independent growth of malignant mesothelioma cells
Cancer Res.
2009
69: 1485-1493
|
| 19325129 |
Schwarz Q et al.:
Neuropilin 1 signaling guides neural crest cells to coordinate pathway choice with cell specification.
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 6164-6169
|
| 9331345 |
Taniguchi M et al.:
Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection
Neuron
1997
19: 519-530
|
| 18708346 |
Bae D et al.:
Metabolic stress induces the lysosomal degradation of neuropilin-1 but not neuropilin-2
J. Biol. Chem.
2008
283
|
| 18708346 |
Bae D et al.:
Metabolic stress induces the lysosomal degradation of neuropilin-1 but not neuropilin-2.
J. Biol. Chem.
2008
283
|
| 18664627 |
Kawamura H et al.:
Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization.
Blood
2008
112: 3638-3649
|
| 16966330 |
Lamalice L et al.:
Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF.
J. Biol. Chem.
2006
281
|
| 14724572 |
Lamalice L et al.:
Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38.
Oncogene
2004
23: 434-445
|
| 17569671 |
Guttmann-Raviv N et al.:
Semaphorin-3A and semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis.
J. Biol. Chem.
2007
282
|
| 18056484 |
Moretti S et al.:
Semaphorin3A signaling controls Fas (CD95)-mediated apoptosis by promoting Fas translocation into lipid rafts.
Blood
2008
111: 2290-2299
|
| 9215629 |
Yang X et al.:
Daxx, a novel Fas-binding protein that activates JNK and apoptosis
Cell
1997
89: 1067-1076
|
| 16330548 |
Kurschat P et al.:
Neuron restrictive silencer factor NRSF/REST is a transcriptional repressor of neuropilin-1 and diminishes the ability of semaphorin 3A to inhibit keratinocyte migration.
J. Biol. Chem.
2006
281: 2721-2729
|
| 17369826 |
Semenova MM et al.:
Rho mediates calcium-dependent activation of p38alpha and subsequent excitotoxic cell death
Nat. Neurosci.
2007
10: 436-443
|
| 19251628 |
Vance C et al. et al.:
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
Science
2009
323: 1208-1211
|
| 18309045 |
Sreedharan J et al.:
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
Science
2008
319: 1668-1672
|
| 17023659 |
Neumann M et al. et al.:
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Science
2006
314: 130-133
|
| 17469116 |
Mackenzie IR et al. et al.:
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
Ann. Neurol.
2007
61: 427-434
|
| 8446170 |
Rosen DR et al.:
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
Nature
1993
362: 59-62
|
| 10196546 |
Takahashi T et al.:
Semaphorins A and E act as antagonists of neuropilin-1 and agonists of neuropilin-2 receptors.
Nat. Neurosci.
1998
1: 487-493
|
| 10520994 |
Takahashi T et al.:
Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors
Cell
1999
99: 59-69
|
| 16495486 |
Chadborn NH et al.:
PTEN couples Sema3A signalling to growth cone collapse
J. Cell. Sci.
2006
119: 951-957
|
| 16495486 |
Chadborn NH et al.:
PTEN couples Sema3A signalling to growth cone collapse.
J. Cell. Sci.
2006
119: 951-957
|
| 11956225 |
Eickholt BJ et al.:
An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling.
J. Cell Biol.
2002
157: 211-217
|
| 18180379 |
Acevedo LM et al.:
Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor.
Blood
2008
111: 2674-2680
|
| 18180379 |
Acevedo LM et al.:
Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor
Blood
2008
111: 2674-2680
|
| 18327764 |
Gallo G et al.:
Semaphorin 3A inhibits ERM protein phosphorylation in growth cone filopodia through inactivation of PI3K
Dev Neurobiol
2008
68: 926-933
|
| 9236236 |
Jin Z et al.:
Rac1 mediates collapsin-1-induced growth cone collapse.
J. Neurosci.
1997
17: 6256-6263
|
| 18272814 |
Narazaki M et al.:
Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A
Blood
2008
111: 4126-4136
|
| 15378658 |
Weydt P et al.:
Increased cytotoxic potential of microglia from ALS-transgenic mice
Glia
2004
48: 179-182
|
| 19672969 |
Zhao W et al.:
Extracellular mutant SOD1 induces microglial-mediated motoneuron injury
Glia
2010
58: 231-243
|
| 18519638 |
Nishitoh H et al.:
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
Genes Dev
2008
22: 1451-1464
|
| 12847526 |
Lambrechts D et al.:
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death.
Nat. Genet.
2003
34: 383-394
|
| 11381259 |
Oosthuyse B et al.:
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.
Nat. Genet.
2001
28: 131-138
|
| 18519638 |
Nishitoh H et al.:
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
Genes Dev.
2008
22: 1451-1464
|
| 18519638 |
Nishitoh H et al.:
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
Genes Dev.
2008
22: 1451-1464
|
| 19762508 |
Hetz C et al.:
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
Genes Dev.
2009
23: 2294-2306
|
| 19762508 |
Hetz C et al.:
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy.
Genes Dev.
2009
23: 2294-2306
|
| 15568021 |
Storkebaum E et al.:
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.
Nat. Neurosci.
2005
8: 85-92
|
| 19183264 |
Suzuki H et al.:
ALS-linked P56S-VAPB, an aggregated loss-of-function mutant of VAPB, predisposes motor neurons to ER stress-related death by inducing aggregation of co-expressed wild-type VAPB
J. Neurochem.
2009
108: 973-985
|
| 18233996 |
Oh YK et al.:
Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells
J. Neurochem.
2008
104: 993-1005
|
| 19330001 |
Saxena S et al.:
A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice
Nat. Neurosci.
2009
12: 627-636
|
| 19330001 |
Saxena S et al.:
A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice.
Nat. Neurosci.
2009
12: 627-636
|
| 18077368 |
Kieran D et al.:
Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice.
Proc. Natl. Acad. Sci. U.S.A.
2007
104
|
| 18077368 |
Kieran D et al.:
Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice
Proc. Natl. Acad. Sci. U.S.A.
2007
104
|
| 18413601 |
Taoufik E et al.:
TNF receptor I sensitizes neurons to erythropoietin- and VEGF-mediated neuroprotection after ischemic and excitotoxic injury.
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 6185-6190
|
| 18413601 |
Taoufik E et al.:
TNF receptor I sensitizes neurons to erythropoietin- and VEGF-mediated neuroprotection after ischemic and excitotoxic injury
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 6185-6190
|
| 7507336 |
Cheng B et al.:
Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis
Neuron
1994
12: 139-153
|
| 11029549 |
Jin KL et al.:
Induction of vascular endothelial growth factor and hypoxia-inducible factor-1alpha by global ischemia in rat brain.
Neuroscience
2000
99: 577-585
|
| 16847061 |
Atkin JD et al.:
Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1
J. Biol. Chem.
2006
281
|
| 16847061 |
Atkin JD et al.:
Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1
J. Biol. Chem.
2006
281
|
| 16847061 |
Atkin JD et al.:
Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1.
J. Biol. Chem.
2006
281
|
| 19661182 |
Ying Z et al.:
Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation.
Hum. Mol. Genet.
2009
18: 4268-4281
|
| 19661182 |
Ying Z et al.:
Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation
Hum. Mol. Genet.
2009
18: 4268-4281
|
| 9618543 |
Rosenstein JM et al.:
Patterns of brain angiogenesis after vascular endothelial growth factor administration in vitro and in vivo.
Proc. Natl. Acad. Sci. U.S.A.
1998
95: 7086-7091
|
| 19661182 |
Ying Z et al.:
Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation
Hum. Mol. Genet.
2009
18: 4268-4281
|
| 9618543 |
Rosenstein JM et al.:
Patterns of brain angiogenesis after vascular endothelial growth factor administration in vitro and in vivo
Proc. Natl. Acad. Sci. U.S.A.
1998
95: 7086-7091
|
| 18566591 |
Jeyabalan A et al.:
Cigarette smoke exposure and angiogenic factors in pregnancy and preeclampsia
Am. J. Hypertens.
2008
21: 943-947
|
| 19889996 |
Yang YS et al.:
Reticulon-4A (Nogo-A) redistributes protein disulfide isomerase to protect mice from SOD1-dependent amyotrophic lateral sclerosis.
J. Neurosci.
2009
29
|
| 17360578 |
Warner-Schmidt JL et al.:
VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants
Proc. Natl. Acad. Sci. U.S.A.
2007
104: 4647-4652
|
| 17360578 |
Warner-Schmidt JL et al.:
VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants.
Proc. Natl. Acad. Sci. U.S.A.
2007
104: 4647-4652
|
| 18263603 |
Gkogkas C et al.:
VAPB interacts with and modulates the activity of ATF6
Hum. Mol. Genet.
2008
17: 1517-1526
|
| 18263603 |
Gkogkas C et al.:
VAPB interacts with and modulates the activity of ATF6
Hum. Mol. Genet.
2008
17: 1517-1526
|
| 16891305 |
Kanekura K et al.:
Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8)
J. Biol. Chem.
2006
281
|
| 16192378 |
McCloskey DP et al.:
Depression of synaptic transmission by vascular endothelial growth factor in adult rat hippocampus and evidence for increased efficacy after chronic seizures
J. Neurosci.
2005
25: 8889-8897
|
| 19109488 |
Kieran D et al.:
Control of motoneuron survival by angiogenin
J. Neurosci.
2008
28
|
| 19109488 |
Kieran D et al.:
Control of motoneuron survival by angiogenin
J. Neurosci.
2008
28
|
| 18065154 |
Nicoletti JN et al.:
Vascular endothelial growth factor is up-regulated after status epilepticus and protects against seizure-induced neuronal loss in hippocampus
Neuroscience
2008
151: 232-241
|
| 18065154 |
Nicoletti JN et al.:
Vascular endothelial growth factor is up-regulated after status epilepticus and protects against seizure-induced neuronal loss in hippocampus.
Neuroscience
2008
151: 232-241
|
| 19444281 |
Sebastia J et al.:
Angiogenin protects motoneurons against hypoxic injury.
Cell Death Differ.
2009
16: 1238-1247
|
| 19444281 |
Sebastia J et al.:
Angiogenin protects motoneurons against hypoxic injury
Cell Death Differ.
2009
16: 1238-1247
|
| 19444281 |
Sebastia J et al.:
Angiogenin protects motoneurons against hypoxic injury
Cell Death Differ.
2009
16: 1238-1247
|
| 15258583 |
Cao L et al.:
VEGF links hippocampal activity with neurogenesis, learning and memory
Nat. Genet.
2004
36: 827-835
|
| 15258583 |
Cao L et al.:
VEGF links hippocampal activity with neurogenesis, learning and memory.
Nat. Genet.
2004
36: 827-835
|
| 16581901 |
Raoul C et al.:
Chronic activation in presymptomatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL
Proc. Natl. Acad. Sci. U.S.A.
2006
103: 6007-6012
|
| 16964394 |
Yoshino Y et al.:
Activation of p38 MAPK and/or JNK contributes to increased levels of VEGF secretion in human malignant glioma cells.
Int. J. Oncol.
2006
29: 981-987
|
| 12354397 |
Raoul C et al.:
Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.
Neuron
2002
35: 1067-1083
|
| 15207859 |
Ackerley S et al.:
p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis
Mol. Cell. Neurosci.
2004
26: 354-364
|
| 15207859 |
Ackerley S et al.:
p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis.
Mol. Cell. Neurosci.
2004
26: 354-364
|
| 15207859 |
Ackerley S et al.:
p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis
Mol. Cell. Neurosci.
2004
26: 354-364
|
| 16000635 |
Martin LJ et al.:
Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation
J. Neurosci.
2005
25: 6449-6459
|
| 16000635 |
Martin LJ et al.:
Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation
J. Neurosci.
2005
25: 6449-6459
|
| 12812752 |
Tortarolo M et al.:
Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression
Mol. Cell. Neurosci.
2003
23: 180-192
|
| 17630988 |
Petri S et al.:
The lipophilic metal chelators DP-109 and DP-460 are neuroprotective in a transgenic mouse model of amyotrophic lateral sclerosis
J. Neurochem.
2007
102: 991-1000
|
| 19091752 |
Liu Y et al.:
Expression of amyotrophic lateral sclerosis-linked SOD1 mutant increases the neurotoxic potential of microglia via TLR2
J. Biol. Chem.
2009
284: 3691-3699
|
| 16510725 |
Kiaei M et al.:
Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis
J. Neurosci.
2006
26: 2467-2473
|
| 16510725 |
Kiaei M et al.:
Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis.
J. Neurosci.
2006
26: 2467-2473
|
| 19734218 |
D'Ambrosi N et al.:
The proinflammatory action of microglial P2 receptors is enhanced in SOD1 models for amyotrophic lateral sclerosis
J. Immunol.
2009
183: 4648-4656
|
| 16512913 |
Yiangou Y et al.:
COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord.
BMC Neurol
2006
6: 12
|
| 16619237 |
Almer G et al.:
Is prostaglandin E(2) a pathogenic factor in amyotrophic lateral sclerosis
Ann. Neurol.
2006
59: 980-983
|
| 19477238 |
Mir M et al.:
Tumor necrosis factor alpha and interferon gamma cooperatively induce oxidative stress and motoneuron death in rat spinal cord embryonic explants
Neuroscience
2009
162: 959-971
|
| 18219391 |
Harraz MM et al.:
SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model
J. Clin. Invest.
2008
118: 659-670
|
| 18219391 |
Harraz MM et al.:
SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model
J. Clin. Invest.
2008
118: 659-670
|
| 17853944 |
Marden JJ et al.:
Redox modifier genes in amyotrophic lateral sclerosis in mice
J. Clin. Invest.
2007
117: 2913-2919
|
| 17389365 |
Son M et al.:
Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology
Proc. Natl. Acad. Sci. U.S.A.
2007
104: 6072-6077
|
| 19765191 |
Gal J et al.:
Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism
J. Neurochem.
2009
111: 1062-1073
|
| 19765191 |
Gal J et al.:
Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism
J. Neurochem.
2009
111: 1062-1073
|
| 19793721 |
Ferguson CJ et al.:
Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2.
Hum. Mol. Genet.
2009
18: 4868-4878
|
| 19793721 |
Ferguson CJ et al.:
Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2
Hum. Mol. Genet.
2009
18: 4868-4878
|
| 19944744 |
Wang X et al.:
Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin-proteasome system
Neurosci. Lett.
2010
469: 112-116
|
| 18250315 |
Fornai F et al.:
Lithium delays progression of amyotrophic lateral sclerosis
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 2052-2057
|
| 18250315 |
Fornai F et al.:
Lithium delays progression of amyotrophic lateral sclerosis.
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 2052-2057
|
| 18337307 |
Proescher JB et al.:
Biological effects of CCS in the absence of SOD1 enzyme activation: implications for disease in a mouse model for ALS
Hum. Mol. Genet.
2008
17: 1728-1737
|
| 19656261 |
Tokuda E et al.:
Dysregulation of intracellular copper trafficking pathway in a mouse model of mutant copper/zinc superoxide dismutase-linked familial amyotrophic lateral sclerosis
J. Neurochem.
2009
111: 181-191
|
| 19765193 |
Boylan K et al.:
Immunoreactivity of the phosphorylated axonal neurofilament H subunit (pNF-H) in blood of ALS model rodents and ALS patients: evaluation of blood pNF-H as a potential ALS biomarker
J. Neurochem.
2009
111: 1182-1191
|
| 19765193 |
Boylan K et al.:
Immunoreactivity of the phosphorylated axonal neurofilament H subunit (pNF-H) in blood of ALS model rodents and ALS patients: evaluation of blood pNF-H as a potential ALS biomarker.
J. Neurochem.
2009
111: 1182-1191
|
| 18003833 |
Yamashita N et al.:
Regulation of spine development by semaphorin3A through cyclin-dependent kinase 5 phosphorylation of collapsin response mediator protein 1.
J. Neurosci.
2007
27
|
| 14762105 |
Shea TB et al.:
Cdk5 regulates axonal transport and phosphorylation of neurofilaments in cultured neurons
J. Cell. Sci.
2004
117: 933-941
|
| 18519042 |
Manser C et al.:
Deregulation of PKN1 activity disrupts neurofilament organisation and axonal transport.
FEBS Lett.
2008
582: 2303-2308
|
| 18519042 |
Manser C et al.:
Deregulation of PKN1 activity disrupts neurofilament organisation and axonal transport
FEBS Lett.
2008
582: 2303-2308
|
| 19717447 |
Zhu X et al.:
MSC p43 required for axonal development in motor neurons.
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 10893265 |
Ackerley S et al.:
Glutamate slows axonal transport of neurofilaments in transfected neurons.
J. Cell Biol.
2000
150: 165-176
|
| 11082065 |
El-Husseini AE et al.:
PSD-95 involvement in maturation of excitatory synapses.
Science
2000
290: 1364-1368
|
| 17344389 |
Su KY et al.:
Mice deficient in collapsin response mediator protein-1 exhibit impaired long-term potentiation and impaired spatial learning and memory
J. Neurosci.
2007
27: 2513-2524
|
| 17344389 |
Su KY et al.:
Mice deficient in collapsin response mediator protein-1 exhibit impaired long-term potentiation and impaired spatial learning and memory.
J. Neurosci.
2007
27: 2513-2524
|
| 15372378 |
Nishimura AL et al.:
A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
Am. J. Hum. Genet.
2004
75: 822-831
|
| 20008544 |
Fasana E et al.:
A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum
FASEB J.
2010
24: 1419-1430
|
| 16945901 |
Ferri A et al.:
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials
Proc. Natl. Acad. Sci. U.S.A.
2006
103
|
| 9853749 |
Migaud M et al.:
Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein
Nature
1998
396: 433-439
|
| 19344252 |
Cozzolino M et al.:
Oligomerization of mutant SOD1 in mitochondria of motoneuronal cells drives mitochondrial damage and cell toxicity.
Antioxid. Redox Signal.
2009
11: 1547-1558
|
| 20007902 |
Williams AH et al.:
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice
Science
2009
326: 1549-1554
|
| 18715867 |
Kawamata H et al.:
Lysyl-tRNA synthetase is a target for mutant SOD1 toxicity in mitochondria
J. Biol. Chem.
2008
283
|
| 20007902 |
Williams AH et al.:
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice.
Science
2009
326: 1549-1554
|
| 17099709 |
Kaneko S et al.:
A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord.
Nat. Med.
2006
12: 1380-1389
|
| 16478527 |
Damiano M et al.:
Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice
J. Neurochem.
2006
96: 1349-1361
|
| 9705358 |
Giraudo E et al.:
Tumor necrosis factor-alpha regulates expression of vascular endothelial growth factor receptor-2 and of its co-receptor neuropilin-1 in human vascular endothelial cells.
J. Biol. Chem.
1998
273
|
| 12649282 |
Duval M et al.:
Vascular endothelial growth factor-dependent down-regulation of Flk-1/KDR involves Cbl-mediated ubiquitination. Consequences on nitric oxide production from endothelial cells.
J. Biol. Chem.
2003
278
|
| 19041930 |
Tolosa L et al.:
Vascular endothelial growth factor protects motoneurons from serum deprivation-induced cell death through phosphatidylinositol 3-kinase-mediated p38 mitogen-activated protein kinase inhibition.
Neuroscience
2009
158: 1348-1355
|
| 18182045 |
Tolosa L et al.:
Vascular endothelial growth factor protects spinal cord motoneurons against glutamate-induced excitotoxicity via phosphatidylinositol 3-kinase.
J. Neurochem.
2008
105: 1080-1090
|
| 15233914 |
Pasinelli P et al.:
Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria.
Neuron
2004
43: 19-30
|
| 17855507 |
Duval M et al.:
Src-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase.
Mol. Biol. Cell
2007
18: 4659-4668
|
| 15233914 |
Pasinelli P et al.:
Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria
Neuron
2004
43: 19-30
|
| 16710367 |
Crosio C et al.:
Bcl2a1 serves as a switch in death of motor neurons in amyotrophic lateral sclerosis
Cell Death Differ.
2006
13: 2150-2153
|
| 16710367 |
Crosio C et al.:
Bcl2a1 serves as a switch in death of motor neurons in amyotrophic lateral sclerosis
Cell Death Differ.
2006
13: 2150-2153
|
| 19545440 |
Jaiswal MK et al.:
Impairment of mitochondrial calcium handling in a mtSOD1 cell culture model of motoneuron disease.
BMC Neurosci
2009
10: 64
|
| 16928866 |
Gould TW et al.:
Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS.
J. Neurosci.
2006
26: 8774-8786
|
| 19046404 |
Soo KY et al.:
Recruitment of mitochondria into apoptotic signaling correlates with the presence of inclusions formed by amyotrophic lateral sclerosis-associated SOD1 mutations
J. Neurochem.
2009
108: 578-590
|
| 17394546 |
Ezzi SA et al.:
Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation
J. Neurochem.
2007
102: 170-178
|
| 17394546 |
Ezzi SA et al.:
Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation
J. Neurochem.
2007
102: 170-178
|
| 17394546 |
Ezzi SA et al.:
Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation.
J. Neurochem.
2007
102: 170-178
|
| 19638399 |
Kupershmidt L et al.:
Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis
FASEB J.
2009
23: 3766-3779
|
| 19523650 |
Fang L et al.:
Linking neuron and skin: matrix metalloproteinases in amyotrophic lateral sclerosis (ALS).
J. Neurol. Sci.
2009
285: 62-66
|
| 17362932 |
Kiaei M et al.:
Matrix metalloproteinase-9 regulates TNF-alpha and FasL expression in neuronal, glial cells and its absence extends life in a transgenic mouse model of amyotrophic lateral sclerosis
Exp. Neurol.
2007
205: 74-81
|
| 20097566 |
Soon CP et al.:
Serum matrix metalloproteinase-9 activity is dysregulated with disease progression in the mutant SOD1 transgenic mice
Neuromuscul. Disord.
2010
20: 260-266
|
| 15358145 |
Choi JS et al.:
Co-chaperone CHIP associates with mutant Cu/Zn-superoxide dismutase proteins linked to familial amyotrophic lateral sclerosis and promotes their degradation by proteasomes
Biochem. Biophys. Res. Commun.
2004
321: 574-583
|
| 15358145 |
Choi JS et al.:
Co-chaperone CHIP associates with mutant Cu/Zn-superoxide dismutase proteins linked to familial amyotrophic lateral sclerosis and promotes their degradation by proteasomes
Biochem. Biophys. Res. Commun.
2004
321: 574-583
|
| 15198682 |
Urushitani M et al.:
CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70
J. Neurochem.
2004
90: 231-244
|
| 19610091 |
Sone J et al.:
Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis
J. Neurosci. Res.
2010
88: 123-135
|
| 15201339 |
Nguyen DT et al.:
Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress
Mol. Biol. Cell
2004
15: 4248-4260
|
| 15201339 |
Nguyen DT et al.:
Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress.
Mol. Biol. Cell
2004
15: 4248-4260
|
| 12145308 |
Niwa J et al.:
Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity
J. Biol. Chem.
2002
277
|
| 12145308 |
Niwa J et al.:
Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity.
J. Biol. Chem.
2002
277
|
| 17666395 |
Niwa J et al.:
Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1.
J. Biol. Chem.
2007
282
|
| 14684739 |
Miyazaki K et al.:
NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1
J. Biol. Chem.
2004
279
|
| 14684739 |
Miyazaki K et al.:
NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.
J. Biol. Chem.
2004
279
|
| 19179380 |
Lee J et al.:
Activation of Ets-2 by oxidative stress induces Bcl-xL expression and accounts for glial survival in amyotrophic lateral sclerosis
FASEB J.
2009
23: 1739-1749
|
| 17925878 |
Yamagishi S et al.:
An in vitro model for Lewy body-like hyaline inclusion/astrocytic hyaline inclusion: induction by ER stress with an ALS-linked SOD1 mutation
PLoS ONE
2007
2: E1030
|
| 20223753 |
Wong M et al.:
Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice
Hum. Mol. Genet.
2010
19: 2284-2302
|
| 18706911 |
Pierce A et al.:
GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosis
J. Mol. Biol.
2008
382: 1195-1210
|
| 16043017 |
Poon HF et al.:
Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis
Free Radic. Biol. Med.
2005
39: 453-462
|
| 17584954 |
Muller FL et al.:
Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production.
Am. J. Physiol. Regul. Integr. Comp. Physiol.
2007
293
|
| 17584954 |
Muller FL et al.:
Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production
Am. J. Physiol. Regul. Integr. Comp. Physiol.
2007
293
|
| 20007371 |
Gros-Louis F et al.:
Chromogranin B P413L variant as risk factor and modifier of disease onset for amyotrophic lateral sclerosis.
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 20007371 |
Gros-Louis F et al.:
Chromogranin B P413L variant as risk factor and modifier of disease onset for amyotrophic lateral sclerosis
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 20198480 |
Kraemer BC et al.:
Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis.
Acta Neuropathol.
2010
119: 409-419
|
| 19379745 |
Feiguin F et al.:
Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior.
FEBS Lett.
2009
583: 1586-1592
|
| 19816510 |
Wang M et al.:
Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis
Cell Death Differ.
2010
17: 488-498
|
| 20188146 |
Tudor EL et al.:
Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology
Neuroscience
2010
167: 774-785
|
| 16835242 |
Latreille M et al.:
Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress
J. Biol. Chem.
2006
281
|
| 16835242 |
Latreille M et al.:
Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress
J. Biol. Chem.
2006
281
|
| 16835242 |
Latreille M et al.:
Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress.
J. Biol. Chem.
2006
281
|
| 19383787 |
Zhang YJ et al.:
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity.
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 7607-7612
|
| 19805353 |
Iwawaki T et al.:
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability.
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 19805353 |
Iwawaki T et al.:
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 20379728 |
Braak H et al.:
Amyotrophic lateral sclerosis: dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord
Acta Neuropathol.
2010
120: 67-74
|
| 20043239 |
Shiina Y et al.:
TDP-43 dimerizes in human cells in culture
Cell. Mol. Neurobiol.
2010
30: 641-652
|
| 20071528 |
Barmada SJ et al.:
Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis
J. Neurosci.
2010
30: 639-649
|
| 19251627 |
Kwiatkowski TJ Jr et al.:
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.
Science
2009
323: 1205-1208
|
| 18923022 |
Poesen K et al.:
Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration.
J. Neurosci.
2008
28
|
| 18923022 |
Poesen K et al.:
Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration
J. Neurosci.
2008
28
|
| 18923022 |
Poesen K et al.:
Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration
J. Neurosci.
2008
28
|
| 17652584 |
Lu L et al.:
Mutant Cu/Zn-superoxide dismutase associated with amyotrophic lateral sclerosis destabilizes vascular endothelial growth factor mRNA and downregulates its expression
J. Neurosci.
2007
27: 7929-7938
|
| 17652584 |
Lu L et al.:
Mutant Cu/Zn-superoxide dismutase associated with amyotrophic lateral sclerosis destabilizes vascular endothelial growth factor mRNA and downregulates its expression.
J. Neurosci.
2007
27: 7929-7938
|
| 19196430 |
Li X et al.:
Mutant copper-zinc superoxide dismutase associated with amyotrophic lateral sclerosis binds to adenine/uridine-rich stability elements in the vascular endothelial growth factor 3-untranslated region.
J. Neurochem.
2009
108: 1032-1044
|
| 19622636 |
Uemura A et al.:
Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response.
J. Cell. Sci.
2009
122: 2877-2886
|
| 17403682 |
Zhang F et al.:
Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex.
J. Biol. Chem.
2007
282
|
| 17403682 |
Zhang F et al.:
Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex
J. Biol. Chem.
2007
282
|
| 18515363 |
Strom AL et al.:
Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation
J. Biol. Chem.
2008
283
|
| 18719118 |
Ilieva HS et al.:
Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death
Proc. Natl. Acad. Sci. U.S.A.
2008
105
|
| 18719118 |
Ilieva HS et al.:
Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death
Proc. Natl. Acad. Sci. U.S.A.
2008
105
|
| 18178312 |
Gomes E et al.:
p38 MAPK as a negative regulator of VEGF/VEGFR2 signaling pathway in serum deprived human SK-N-SH neuroblastoma cells
Neurosci. Lett.
2008
431: 95-100
|
| 11445557 |
Chen R et al.:
Regulation of Akt/PKB activation by tyrosine phosphorylation.
J. Biol. Chem.
2001
276
|
| 20020442 |
Price J et al.:
Akt-1 mediates survival of chondrocytes from endoplasmic reticulum-induced stress.
J. Cell. Physiol.
2010
222: 502-508
|
| 15911875 |
Kieran D et al.:
A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice
J. Cell Biol.
2005
169: 561-567
|
| 12730604 |
Hafezparast M et al.:
Mutations in dynein link motor neuron degeneration to defects in retrograde transport
Science
2003
300: 808-812
|
| 20428114 |
Maruyama H et al. et al.:
Mutations of optineurin in amyotrophic lateral sclerosis
Nature
2010
465: 223-226
|
| 20428114 |
Maruyama H et al.:
Mutations of optineurin in amyotrophic lateral sclerosis.
Nature
2010
465: 223-226
|
| 19657041 |
Perlson E et al.:
A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration
J. Neurosci.
2009
29: 9903-9917
|
| 15339911 |
Hu P et al.:
Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
J. Biol. Chem.
2004
279
|
| 15339911 |
Hu P et al.:
Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death.
J. Biol. Chem.
2004
279
|
| 12654515 |
Li B et al.:
VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death
Brain Res. Mol. Brain Res.
2003
111: 155-164
|
| 17991856 |
Lin JH et al.:
IRE1 signaling affects cell fate during the unfolded protein response.
Science
2007
318: 944-949
|
| 18305234 |
Laird FM et al.:
Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking
J. Neurosci.
2008
28: 1997-2005
|
| 18094236 |
Lai C et al.:
The G59S mutation in p150(glued) causes dysfunction of dynactin in mice
J. Neurosci.
2007
27
|
| 18701194 |
Anagnostou G et al.:
Vesicle associated membrane protein B (VAPB) is decreased in ALS spinal cord.
Neurobiol. Aging
2010
31: 969-985
|
| 18555774 |
Tsuda H et al.:
The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors.
Cell
2008
133: 963-977
|
| 18344992 |
Zhong Z et al.:
ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration
Nat. Neurosci.
2008
11: 420-422
|
| 18030339 |
Garbuzova-Davis S et al.:
Evidence of compromised blood-spinal cord barrier in early and late symptomatic SOD1 mice modeling ALS
PLoS ONE
2007
2: E1205
|
| 19841542 |
Zhong Z et al.:
Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells
J. Clin. Invest.
2009
119: 3437-3449
|
| 19841542 |
Zhong Z et al.:
Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells
J. Clin. Invest.
2009
119: 3437-3449
|
| 18250315 |
Fornai F et al. et al.:
Lithium delays progression of amyotrophic lateral sclerosis
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 2052-2057
|
| 16236328 |
Shao L et al.:
Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells.
Life Sci.
2006
78: 1317-1323
|
| 15980862 |
Ravikumar B et al.:
Dynein mutations impair autophagic clearance of aggregate-prone proteins.
Nat. Genet.
2005
37: 771-776
|
| 14960605 |
Nguyen MD et al.:
Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis
J. Neurosci.
2004
24: 1340-1349
|
| 15056289 |
Pehar M et al.:
Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis
J. Neurochem.
2004
89: 464-473
|
| 20138122 |
Milane A et al.:
P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis
Neurosci. Lett.
2010
472: 166-170
|
| 11754077 |
Cassina P et al.:
Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis
J. Neurosci. Res.
2002
67: 21-29
|
| 19733563 |
Neymotin A et al.:
Lenalidomide (Revlimid) administration at symptom onset is neuroprotective in a mouse model of amyotrophic lateral sclerosis
Exp. Neurol.
2009
220: 191-197
|
| 20616880 |
Huang C et al.:
Sustained expression of TDP-43 and FUS in motor neurons in rodents lifetime
Int. J. Biol. Sci.
2010
6: 396-406
|
| 20606625 |
Dormann D et al.:
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
EMBO J.
2010
29: 2841-2857
|
| 20606625 |
Dormann D et al.:
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
EMBO J.
2010
29: 2841-2857
|
| 17481916 |
Strong MJ et al.:
TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein
Mol. Cell. Neurosci.
2007
35: 320-327
|
| 17481916 |
Strong MJ et al.:
TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein
Mol. Cell. Neurosci.
2007
35: 320-327
|
| 20517935 |
Deng HX et al.:
FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis
Ann. Neurol.
2010
67: 739-748
|
| 18305110 |
Winton MJ et al.:
Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation
J. Biol. Chem.
2008
283
|
| 20570967 |
Crippa V et al.:
The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)
Hum. Mol. Genet.
2010
19: 3440-3456
|
| 20570967 |
Crippa V et al. et al.:
The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)
Hum. Mol. Genet.
2010
19: 3440-3456
|
| 20624952 |
Ling SC et al.:
ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 19815002 |
Volkening K et al.:
Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS)
Brain Res.
2009
1305: 168-182
|
| 20138212 |
Caragounis A et al.:
Zinc induces depletion and aggregation of endogenous TDP-43
Free Radic. Biol. Med.
2010
48: 1152-1161
|
| 16877542 |
Wu DC et al.:
The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice
Proc. Natl. Acad. Sci. U.S.A.
2006
103
|
| 20219021 |
Rentzos M et al.:
Interleukin-17 and interleukin-23 are elevated in serum and cerebrospinal fluid of patients with ALS: a reflection of Th17 cells activation
Acta Neurol. Scand.
2010
122: 425-429
|
| 19752764 |
Sargsyan SA et al.:
Mutant SOD1 G93A microglia have an inflammatory phenotype and elevated production of MCP-1
Neuroreport
2009
20: 1450-1455
|
| 17852013 |
Rentzos M et al.:
RANTES levels are elevated in serum and cerebrospinal fluid in patients with amyotrophic lateral sclerosis
Amyotroph Lateral Scler
2007
8: 283-287
|
| 18997009 |
Chiu IM et al.:
T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS
Proc. Natl. Acad. Sci. U.S.A.
2008
105
|
| 20071543 |
Duplan L et al.:
Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SOD1 mice and can trigger motoneuron axonal degeneration and cell death
J. Neurosci.
2010
30: 785-796
|
| 20071543 |
Duplan L et al.:
Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SOD1 mice and can trigger motoneuron axonal degeneration and cell death
J. Neurosci.
2010
30: 785-796
|
| 19323997 |
Yang Y et al.:
Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1
Neuron
2009
61: 880-894
|
| 19323997 |
Yang Y et al.:
Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1
Neuron
2009
61: 880-894
|
| 11818550 |
Howland DS et al.:
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
Proc. Natl. Acad. Sci. U.S.A.
2002
99: 1604-1609
|
| 19074031 |
Vargas MR et al.:
Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis
J. Neurosci.
2008
28
|
| 14755726 |
Henkel JS et al.:
Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue
Ann. Neurol.
2004
55: 221-235
|
| 19429692 |
D'Ambrogio A et al.:
Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo
Nucleic Acids Res.
2009
37: 4116-4126
|
| 19910924 |
Fiesel FC et al.:
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6
EMBO J.
2010
29: 209-221
|
| 19910924 |
Fiesel FC et al.:
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6
EMBO J.
2010
29: 209-221
|
| 20361056 |
Zhou H et al.:
Transgenic rat model of neurodegeneration caused by mutation in the TDP gene
PLoS Genet.
2010
6
|
| 17555556 |
Xiao Q et al.:
Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia
J. Neurochem.
2007
102: 2008-2019
|
| 19888600 |
Chen K et al.:
Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice
Brain Struct Funct
2010
214: 219-234
|
| 19236470 |
Kuhle J et al.:
Increased levels of inflammatory chemokines in amyotrophic lateral sclerosis
Eur. J. Neurol.
2009
16: 771-774
|
| 19236470 |
Kuhle J et al.:
Increased levels of inflammatory chemokines in amyotrophic lateral sclerosis
Eur. J. Neurol.
2009
16: 771-774
|
| 19005069 |
Cheret C et al.:
Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase.
J. Neurosci.
2008
28
|
| 18598679 |
Li B et al.:
The NADPH oxidase is involved in lipopolysaccharide-mediated motor neuron injury.
Brain Res.
2008
1226: 199-208
|
| 19307024 |
Mantovani S et al.:
Immune system alterations in sporadic amyotrophic lateral sclerosis patients suggest an ongoing neuroinflammatory process
J. Neuroimmunol.
2009
210: 73-79
|
| 20544912 |
Mitchell RM et al.:
Plasma biomarkers associated with ALS and their relationship to iron homeostasis
Muscle Nerve
2010
42: 95-103
|
| 18825663 |
Liang X et al.:
The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis
Ann. Neurol.
2008
64: 304-314
|
| 18825663 |
Liang X et al.:
The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis
Ann. Neurol.
2008
64: 304-314
|
| 19539030 |
Casafont I et al.:
TDP-43 localizes in mRNA transcription and processing sites in mammalian neurons
J. Struct. Biol.
2009
167: 235-241
|
| 20740007 |
Elden AC et al. et al.:
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
Nature
2010
466: 1069-1075
|
| 20579074 |
Huang EJ et al.:
Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions
Brain Pathol.
2010
20: 1069-1076
|
| 20544928 |
Rademakers R et al.:
Fus gene mutations in familial and sporadic amyotrophic lateral sclerosis
Muscle Nerve
2010
42: 170-176
|
| 20154090 |
Hanson KA et al.:
Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS)
J. Biol. Chem.
2010
285
|
| 19112176 |
Kim SH et al.:
Potentiation of amyotrophic lateral sclerosis (ALS)-associated TDP-43 aggregation by the proteasome-targeting factor, ubiquilin 1
J. Biol. Chem.
2009
284: 8083-8092
|
| 19887443 |
Nishimoto Y et al.:
Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43.
J. Biol. Chem.
2010
285: 608-619
|
| 17898224 |
Zhang YJ et al.:
Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43
J. Neurosci.
2007
27
|
| 20600671 |
Duan W et al.:
Mutant TAR DNA-binding protein-43 induces oxidative injury in motor neuron-like cell
Neuroscience
2010
169: 1621-1629
|
| 20133711 |
Wils H et al.:
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 3858-3863
|
| 18546284 |
Hasegawa M et al.:
Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Ann. Neurol.
2008
64: 60-70
|
| 18546284 |
Hasegawa M et al.:
Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Ann. Neurol.
2008
64: 60-70
|
| 20303959 |
Guo Y et al.:
Decreased GLT-1 and increased SOD1 and HO-1 expression in astrocytes contribute to lumbar spinal cord vulnerability of SOD1-G93A transgenic mice
FEBS Lett.
2010
584: 1615-1622
|
| 19223871 |
Tatom JB et al.:
Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrigs disease in rats via TDP-43 overexpression
Mol. Ther.
2009
17: 607-613
|
| 19833869 |
Wegorzewska I et al.:
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 20660762 |
Chiang PM et al.:
Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 16369483 |
Urushitani M et al.:
Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis
Nat. Neurosci.
2006
9: 108-118
|
| 16369483 |
Urushitani M et al.:
Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis
Nat. Neurosci.
2006
9: 108-118
|
| 20829229 |
Ferri A et al.:
Glutaredoxin 2 prevents aggregation of mutant SOD1 in mitochondria and abolishes its toxicity
Hum. Mol. Genet.
2010
19: 4529-4542
|
| 20202083 |
Yamashita S et al.:
DJ-1 forms complexes with mutant SOD1 and ameliorates its toxicity
J. Neurochem.
2010
113: 860-870
|
| 20202083 |
Yamashita S et al.:
DJ-1 forms complexes with mutant SOD1 and ameliorates its toxicity
J. Neurochem.
2010
113: 860-870
|
| 19889637 |
Zhou J et al.:
Hyperactive intracellular calcium signaling associated with localized mitochondrial defects in skeletal muscle of an animal model of amyotrophic lateral sclerosis
J. Biol. Chem.
2010
285: 705-712
|
| 20460269 |
Pedrini S et al.:
ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2
Hum. Mol. Genet.
2010
19: 2974-2986
|
| 20460269 |
Pedrini S et al.:
ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2
Hum. Mol. Genet.
2010
19: 2974-2986
|
| 17510659 |
Hetz C et al.:
The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis
Cell Death Differ.
2007
14: 1386-1389
|
| 17510659 |
Hetz C et al.:
The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis
Cell Death Differ.
2007
14: 1386-1389
|
| 19100675 |
Abutin RM et al.:
Erythropoietin-induced phosphorylation/degradation of BIM contributes to survival of erythroid cells
Exp. Hematol.
2009
37: 151-158
|
| 20456006 |
Tovar-Y-Romo LB et al.:
VEGF protects spinal motor neurons against chronic excitotoxic degeneration in vivo by activation of PI3-K pathway and inhibition of p38MAPK
J. Neurochem.
2010
115: 1090-1101
|
| 19741096 |
Yonashiro R et al.:
Mitochondrial ubiquitin ligase MITOL ubiquitinates mutant SOD1 and attenuates mutant SOD1-induced reactive oxygen species generation
Mol. Biol. Cell
2009
20: 4524-4530
|
| 10650002 |
Urano F et al.:
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
Science
2000
287: 664-666
|
| 17178835 |
Jiang SX et al.:
Neuropilin-1 is a direct target of the transcription factor E2F1 during cerebral ischemia-induced neuronal death in vivo
Mol. Cell. Biol.
2007
27: 1696-1705
|
| 20890041 |
Reyes NA et al.:
Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis
J. Clin. Invest.
2010
120: 3673-3679
|
| 18160256 |
Nawa M et al.:
A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB
Cell. Signal.
2008
20: 493-505
|
| 18086918 |
Kang J et al.:
MyD88-deficient bone marrow cells accelerate onset and reduce survival in a mouse model of amyotrophic lateral sclerosis
J. Cell Biol.
2007
179: 1219-1230
|
| 17725983 |
De Vos KJ et al.:
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
Hum. Mol. Genet.
2007
16: 2720-2728
|
| 12390515 |
Jung C et al.:
Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis
J. Neurochem.
2002
83: 535-545
|
| 15634778 |
Kirkinezos IG et al.:
Cytochrome c association with the inner mitochondrial membrane is impaired in the CNS of G93A-SOD1 mice
J. Neurosci.
2005
25: 164-172
|
| 19240958 |
Lin J et al.:
Specific electron transport chain abnormalities in amyotrophic lateral sclerosis
J. Neurol.
2009
256: 774-782
|
| 12050154 |
Mattiazzi M et al.:
Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice
J. Biol. Chem.
2002
277
|
| 16903849 |
Raimondi A et al.:
Cell culture models to investigate the selective vulnerability of motoneuronal mitochondria to familial ALS-linked G93ASOD1
Eur. J. Neurosci.
2006
24: 387-399
|
| 15758154 |
Vijayvergiya C et al.:
Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice
J. Neurosci.
2005
25: 2463-2470
|
| 18703498 |
Kawamata H et al.:
Different regulation of wild-type and mutant Cu,Zn superoxide dismutase localization in mammalian mitochondria
Hum. Mol. Genet.
2008
17: 3303-3317
|
| 19320055 |
Son M et al.:
Redox susceptibility of SOD1 mutants is associated with the differential response to CCS over-expression in vivo
Neurobiol. Dis.
2009
34: 155-162
|
| 17620987 |
Jiang YM et al.:
Gene expressions specifically detected in motor neurons (dynactin 1, early growth response 3, acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to pathologic markers in sporadic amyotrophic lateral sclerosis
J. Neuropathol. Exp. Neurol.
2007
66: 617-627
|
| 21078990 |
Li Q et al.:
ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 21078990 |
Li Q et al.:
ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 20797535 |
Israelson A et al.:
Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS
Neuron
2010
67: 575-587
|
| 20797535 |
Israelson A et al.:
Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS
Neuron
2010
67: 575-587
|
| 18296640 |
Vande Velde C et al.:
Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 4022-4027
|
| 19779023 |
Magrane J et al.:
Mutant SOD1 in neuronal mitochondria causes toxicity and mitochondrial dynamics abnormalities
Hum. Mol. Genet.
2009
18: 4552-4564
|
| 19272377 |
Martin LJ et al.:
The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice
Exp. Neurol.
2009
218: 333-346
|
| 19174508 |
Nguyen KT et al.:
The Psi(m) depolarization that accompanies mitochondrial Ca2+ uptake is greater in mutant SOD1 than in wild-type mouse motor terminals
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 2007-2011
|
| 19404401 |
Dupuis L et al.:
Muscle mitochondrial uncoupling dismantles neuromuscular junction and triggers distal degeneration of motor neurons
PLoS ONE
2009
4: E5390
|
| 19158288 |
Jeong SY et al.:
Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis
J. Neurosci.
2009
29: 610-619
|
| 17394531 |
Zimmerman MC et al.:
Mutant SOD1-induced neuronal toxicity is mediated by increased mitochondrial superoxide levels
J. Neurochem.
2007
102: 609-618
|
| 16702190 |
Wood-Allum CA et al.:
Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen
Brain
2006
129: 1693-1709
|
| 20127819 |
Morimoto N et al.:
Induction of parkinsonism-related proteins in the spinal motor neurons of transgenic mouse carrying a mutant SOD1 gene
J. Neurosci. Res.
2010
88: 1804-1811
|
| 18712292 |
Lev N et al.:
DJ-1 changes in G93A-SOD1 transgenic mice: implications for oxidative stress in ALS.
J. Mol. Neurosci.
2009
38: 94-102
|
| 17434459 |
Eve DJ et al.:
Transcription factor p53 in degenerating spinal cords.
Brain Res.
2007
1150: 174-181
|
| 17099894 |
Martin LJ et al.:
Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death.
J. Comp. Neurol.
2007
500: 20-46
|
| 19805546 |
Lu L et al.:
Amyotrophic lateral sclerosis-linked mutant SOD1 sequesters Hu antigen R (HuR) and TIA-1-related protein (TIAR): implications for impaired post-transcriptional regulation of vascular endothelial growth factor.
J. Biol. Chem.
2009
284
|
| 17434152 |
Murakami T et al.:
Early decrease of mitochondrial DNA repair enzymes in spinal motor neurons of presymptomatic transgenic mice carrying a mutant SOD1 gene.
Brain Res.
2007
1150: 182-189
|
| 19900586 |
Loizzo S et al.:
Dynamic NAD(P)H post-synaptic autofluorescence signals for the assessment of mitochondrial function in a neurodegenerative disease: monitoring the primary motor cortex of G93A mice, an amyotrophic lateral sclerosis model.
Mitochondrion
2010
10: 108-114
|
| 19379740 |
Bradley LJ et al.:
Increased sensitivity of myoblasts to oxidative stress in amyotrophic lateral sclerosis peripheral tissues.
Exp. Neurol.
2009
218: 92-97
|
| 18417691 |
Cassina P et al.:
Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants.
J. Neurosci.
2008
28: 4115-4122
|
| 21059924 |
Bilsland LG et al.:
Deficits in axonal transport precede ALS symptoms in vivo.
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 20606625 |
Dormann D et al.:
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.
EMBO J.
2010
29: 2841-2857
|
| 25374358 |
Smith BN et al.:
Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS
Neuron
2014
84: 324-331
|
| 28989002 |
Sanfilippo C et al.:
CHI3L1 and CHI3L2 overexpression in motor cortex and spinal cord of sALS patients
Mol. Cell. Neurosci.
2017
85: 162-169
|
| 20079427 |
Halter B et al.:
Oxidative stress in skeletal muscle stimulates early expression of Rad in a mouse model of amyotrophic lateral sclerosis
Free Radic. Biol. Med.
2010
48: 915-923
|
| 23300739 |
Figueroa-Romero C et al.:
Identification of epigenetically altered genes in sporadic amyotrophic lateral sclerosis
PLoS ONE
2012
7
|
| 31784536 |
Yuva-Aydemir Y et al.:
Transcription elongation factor AFF2/FMR2 regulates expression of expanded GGGGCC repeat-containing C9ORF72 allele in ALS/FTD
Nat Commun
2019
10: 5466
|
| 17244347 |
Lederer CW et al.:
Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis
BMC Genomics
2007
8: 26
|
| 17671248 |
Dunckley T et al. et al.:
Whole-genome analysis of sporadic amyotrophic lateral sclerosis
N. Engl. J. Med.
2007
357: 775-788
|
| 24918638 |
Venkova K et al.:
Semaphorin 3A signaling through neuropilin-1 is an early trigger for distal axonopathy in the SOD1G93A mouse model of amyotrophic lateral sclerosis
J. Neuropathol. Exp. Neurol.
2014
73: 702-713
|
| 26704906 |
Figueroa-Romero C et al.:
Expression of microRNAs in human post-mortem amyotrophic lateral sclerosis spinal cords provides insight into disease mechanisms
Mol. Cell. Neurosci.
2016
71: 34-45
|
| 28283675 |
Andres-Benito P et al.:
Amyotrophic lateral sclerosis, gene deregulation in the anterior horn of the spinal cord and frontal cortex area 8: implications in frontotemporal lobar degeneration
Aging (Albany NY)
2017
9: 823-851
|
| 22922411 |
Van Hoecke A et al. et al.:
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
Nat. Med.
2012
18: 1418-1422
|
| 26687981 |
Lewandowski SA et al.:
Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration
Acta Neuropathol.
2016
131: 453-464
|
| 27812125 |
Won YH et al.:
Elucidation of Relevant Neuroinflammation Mechanisms Using Gene Expression Profiling in Patients with Amyotrophic Lateral Sclerosis
PLoS ONE
2016
11
|
| 16807408 |
Parkinson N et al.:
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)
Neurology
2006
67: 1074-1077
|
| 23022214 |
author information missing
article information missing
|
| 22941226 |
author information missing
article information missing
|
| 34856358 |
author information missing
article information missing
|
| 17166276 |
author information missing
article information missing
|
| 11803234 |
Croonenberghs J et al.:
Activation of the inflammatory response system in autism.
Neuropsychobiology
2002
45: 1-6
|
| 19157572 |
Li X et al.:
Elevated immune response in the brain of autistic patients.
J. Neuroimmunol.
2009
207: 111-116
|
| 10693155 |
Croonenberghs J et al.:
Peripheral markers of serotonergic and noradrenergic function in post-pubertal, caucasian males with autistic disorder
Neuropsychopharmacology
2000
22: 275-283
|
| 10693155 |
Croonenberghs J et al.:
Peripheral markers of serotonergic and noradrenergic function in post-pubertal, caucasian males with autistic disorder.
Neuropsychopharmacology
2000
22: 275-283
|
| 21573053 |
Naik US et al.:
A study of nuclear transcription factor-kappa B in childhood autism.
PLoS ONE
2011
6
|
| 21521652 |
Al-ayadhi LY et al.:
Increased serum osteopontin levels in autistic children: relation to the disease severity
Brain Behav. Immun.
2011
25: 1393-1398
|
| 20705131 |
Ashwood P et al.:
Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome
Brain Behav. Immun.
2011
25: 40-45
|
| 12039413 |
Torres AR et al.:
The transmission disequilibrium test suggests that HLA-DR4 and DR13 are linked to autism spectrum disorder
Hum. Immunol.
2002
63: 311-316
|
| 21346746 |
Penzes P et al.:
Dendritic spine pathology in neuropsychiatric disorders
Nat. Neurosci.
2011
14: 285-293
|
| 23596459 |
Gilling M et al.:
Dysfunction of the Heteromeric KV7.3/KV7.5 Potassium Channel is Associated with Autism Spectrum Disorders
Front Genet
2013
4: 54
|
| 19289393 |
Ben-Shachar S et al.:
Microdeletion 15q13.3: a locus with incomplete penetrance for autism, mental retardation, and psychiatric disorders
J. Med. Genet.
2009
46: 382-388
|
| 24776741 |
McCarthy SE et al.:
De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability
|
| 24752249 |
Breitenkamp AF et al.:
Rare mutations of CACNB2 found in autism spectrum disease-affected families alter calcium channel function
PLoS ONE
2014
9
|
| 25707359 |
Chen N et al.:
Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes
Biochim. Biophys. Acta
2015
7: 827-833
|
| 25271084 |
Mullegama SV et al.:
MBD5 haploinsufficiency is associated with sleep disturbance and disrupts circadian pathways common to Smith-Magenis and fragile X syndromes
Eur. J. Hum. Genet.
2015
23: 781-789
|
| 28720891 |
Al-Mubarak B et al. et al.:
Whole exome sequencing reveals inherited and de novo variants in autism spectrum disorder: a trio study from Saudi families
Sci Rep
2017
7: 5679
|
| 26749308 |
Turner TN et al. et al.:
Genome Sequencing of Autism-Affected Families Reveals Disruption of Putative Noncoding Regulatory DNA
Am. J. Hum. Genet.
2016
98: 58-74
|
| 25774383 |
Cartier E et al. et al.:
Rare autism-associated variants implicate syntaxin 1 (STX1 R26Q) phosphorylation and the dopamine transporter (hDAT R51W) in dopamine neurotransmission and behaviors
EBioMedicine
2015
2: 135-146
|
| 18593506 |
Nakamura K et al. et al.:
Genetic and expression analyses reveal elevated expression of syntaxin 1A ( STX1A) in high functioning autism
Int. J. Neuropsychopharmacol.
2008
11: 1073-1084
|
| 22495309 |
O'Roak BJ et al. et al.:
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
Nature
2012
485: 246-250
|
| 30873608 |
Castronovo P et al.:
Phenotypic spectrum of NRXN1 mono- and bi-allelic deficiency: A systematic review
|
| 23995680 |
King IF et al. et al.:
Topoisomerases facilitate transcription of long genes linked to autism
Nature
2013
501: 58-62
|
| 23495017 |
Dabell MP et al. et al.:
Investigation of NRXN1 deletions: clinical and molecular characterization
Am. J. Med. Genet. A
2013
161A: 717-731
|
| 27965028 |
Sajid U et al.:
Two De Novo Mutations in an Autistic Child Who Had Previously Undergone Transplantation for Dilated Cardiomyopathy: The Importance of Keeping an Open Mind
Can J Cardiol
2017
33: 292.e5-292.e7
|
| 18057082 |
et al.:
A patient with vertebral, cognitive and behavioural abnormalities and a de novo deletion of NRXN1alpha
J. Med. Genet.
2008
45: 239-243
|
| 24360806 |
He Z et al. et al.:
Rare-variant extensions of the transmission disequilibrium test: application to autism exome sequence data
Am. J. Hum. Genet.
2014
94: 33-46
|
| 25363760 |
De Rubeis S et al. et al.:
Synaptic, transcriptional and chromatin genes disrupted in autism
Nature
2014
515: 209-215
|
| 28263302 |
C Yuen RK et al. et al.:
Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder
Nat. Neurosci.
2017
20: 602-611
|
| 22542183 |
Iossifov I et al. et al.:
De novo gene disruptions in children on the autistic spectrum
Neuron
2012
74: 285-299
|
| 25363768 |
Iossifov I et al. et al.:
The contribution of de novo coding mutations to autism spectrum disorder
Nature
2014
515: 216-221
|
| 29021403 |
Hamilton MJ et al. et al.:
Heterozygous mutations affecting the protein kinase domain of CDK13 cause a syndromic form of developmental delay and intellectual disability
J. Med. Genet.
2018
55: 28-38
|
| 23275889 |
Prasad A et al. et al.:
A discovery resource of rare copy number variations in individuals with autism spectrum disorder
G3 (Bethesda)
3 (B
2: 1665-1685
|
| 22495311 |
Neale BM et al. et al.:
Patterns and rates of exonic de novo mutations in autism spectrum disorders
Nature
2012
485: 242-245
|
| 28584692 |
Shroff G et al.:
Human Embryonic Stem Cells in the Treatment of Autism: A Case Series
Innov Clin Neurosci
2017
14: 12-16
|
| 22843504 |
Anney R et al. et al.:
Individual common variants exert weak effects on the risk for autism spectrum disorders
Hum. Mol. Genet.
2012
21: 4781-4792
|
| 29346770 |
Takata A et al. et al.:
Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder
Cell Rep
2018
22: 734-747
|
| 22965006 |
Skafidas E et al.:
Predicting the diagnosis of autism spectrum disorder using gene pathway analysis
Mol. Psychiatry
2014
19: 504-510
|
| 18252227 |
Marshall CR et al. et al.:
Structural variation of chromosomes in autism spectrum disorder
Am. J. Hum. Genet.
2008
82: 477-488
|
| 11706102 |
Purcell AE et al.:
Postmortem brain abnormalities of the glutamate neurotransmitter system in autism
Neurology
2001
57: 1618-1628
|
| 21614001 |
Voineagu I et al.:
Transcriptomic analysis of autistic brain reveals convergent molecular pathology
Nature
2011
474: 380-384
|
| 26783092 |
Feng J et al.:
Clinical improvement following vitamin D3 supplementation in Autism Spectrum Disorder
Nutr Neurosci
2017
20: 284-290
|
| 29505902 |
O'Connell KS et al.:
The genetic architecture of schizophrenia, bipolar disorder, obsessive-compulsive disorder and autism spectrum disorder
Mol. Cell. Neurosci.
2018
88: 300-307
|
| 11357950 |
Nelson KB et al.:
Neuropeptides and neurotrophins in neonatal blood of children with autism or mental retardation
Ann. Neurol.
2001
49: 597-606
|
| 21358714 |
Gai X et al. et al.:
Rare structural variation of synapse and neurotransmission genes in autism
Mol. Psychiatry
2012
17: 402-411
|
| 24007566 |
Stamova BS et al.:
Evidence for differential alternative splicing in blood of young boys with autism spectrum disorders
Mol Autism
2013
4: 30
|
| 31277925 |
Nakagawa N et al. et al.:
Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development
Neuron
2019
103: 836-852.e5
|
| 31327155 |
Miryounesi M et al.:
ELMO Domain Containing 1 (ELMOD1) Gene Mutation Is Associated with Mental Retardation and Autism Spectrum Disorder
J. Mol. Neurosci.
2019
69: 312-315
|
| 29428674 |
Quartier A et al.:
Genes and Pathways Regulated by Androgens in Human Neural Cells, Potential Candidates for the Male Excess in Autism Spectrum Disorder
Biol. Psychiatry
2018
84: 239-252
|
| 23279911 |
Boudry-Labis E et al. et al.:
A novel microdeletion syndrome at 9q21.13 characterised by mental retardation, speech delay, epilepsy and characteristic facial features
Eur J Med Genet
2013
56: 163-170
|
| 28251352 |
Zhang J et al. et al.:
Haploinsufficiency of the E3 ubiquitin-protein ligase gene TRIP12 causes intellectual disability with or without autism spectrum disorders, speech delay, and dysmorphic features
Hum. Genet.
2017
136: 377-386
|
| 23838881 |
Talebizadeh Z et al.:
A proof-of-concept study: exon-level expression profiling and alternative splicing in autism using lymphoblastoid cell lines
Psychiatr. Genet.
2014
24: 1-9
|
| 20308993 |
Vorstman JA et al. et al.:
A double hit implicates DIAPH3 as an autism risk gene
Mol. Psychiatry
2011
16: 442-451
|
| 26398136 |
Kuo PH et al. et al.:
Genome-Wide Association Study for Autism Spectrum Disorder in Taiwanese Han Population
PLoS ONE
2015
10
|
| 23756379 |
Poelmans G et al.:
AKAPs integrate genetic findings for autism spectrum disorders
Transl Psychiatry
2013
3: e270
|
| 27479844 |
Krishnan A et al.:
Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder
Nat. Neurosci.
2016
19: 1454-1462
|
| 28628100 |
Geisheker MR et al. et al.:
Hotspots of missense mutation identify neurodevelopmental disorder genes and functional domains
Nat. Neurosci.
2017
20: 1043-1051
|
| 29147782 |
Chiocchetti AG et al. et al.:
Common functional variants of the glutamatergic system in Autism spectrum disorder with high and low intellectual abilities
J Neural Transm (Vienna)
2018
125: 259-271
|
| 27545675 |
Bain JM et al. et al.:
Variants in HNRNPH2 on the X Chromosome Are Associated with a Neurodevelopmental Disorder in Females
Am. J. Hum. Genet.
2016
99: 728-734
|
| 20452682 |
Mostafa GA et al.:
The link of C4B null allele to autism and to a family history of autoimmunity in Egyptian autistic children
J. Neuroimmunol.
2010
223: 115-119
|
| 22589251 |
Harper KM et al.:
Alterations of social interaction through genetic and environmental manipulation of the 22q11.2 gene Sept5 in the mouse brain
Hum. Mol. Genet.
2012
21: 3489-3499
|
| 31923461 |
Loomis C et al.:
Identification of MAGUK scaffold proteins as intracellular binding partners of synaptic adhesion protein Slitrk2
Mol. Cell. Neurosci.
2020
103
|
| 20479760 |
Piton A et al. et al.:
Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia
Mol. Psychiatry
2011
16: 867-880
|
| 25360606 |
Jones RM et al.:
MACROD2 gene associated with autistic-like traits in a general population sample
Psychiatr. Genet.
2014
24: 241-248
|
| 21981781 |
Talkowski ME et al. et al.:
Assessment of 2q23.1 microdeletion syndrome implicates MBD5 as a single causal locus of intellectual disability, epilepsy, and autism spectrum disorder
Am. J. Hum. Genet.
2011
89: 551-563
|
| 27428651 |
Shemesh Y et al. et al.:
Ucn3 and CRF-R2 in the medial amygdala regulate complex social dynamics
Nat. Neurosci.
2016
19: 1489-1496
|
| 26314684 |
Liu X et al. et al.:
Genome-wide Association Study of Autism Spectrum Disorder in the East Asian Populations
Autism Res
2016
9: 340-349
|
| 31094488 |
Torrico B et al.:
Truncating variant burden in high-functioning autism and pleiotropic effects of LRP1 across psychiatric phenotypes }, authors { names std { { name ml Torrico B, affil str From the Departament de Genetica, Microbiologia i Estadistica, Universitat de Barcelona, Spain (Torrico, Vivo-Luque, Fernandez-Castillo, Cormand, Toma); the Institute of Biomedicine, University of Barcelona, Barcelona, Spain (Torrico, Fernandez-Castillo, Cormand, Toma); the Centro de Investigacion Biomedica en Red de Enfermedades Raras (CIBERER), Barcelona, Spain (Torrico, Fernandez-Castillo, Cormand, Toma); the Institut de Recerca Hospital Sant Joan de Deu, Esplugues de Llobregat, Barcelona, Spain (Torrico, Fernandez-Castillo, Cormand); the Neuroscience Research Australia, Sydney, NSW, Australia (Shaw, Fullerton, Toma); the School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia (Shaw, Fullerton, Toma); the Institute for Research in Biomedicine (IRB Barcelona) and the Barcelona Institute of Science and Technology, Barcelona, Spain (Mosca, Aloy); the Child and Adolescent Mental Health Unit, Hospital Universitari Mutua de Terrassa, Spain (Hervas); the Institucio Catalana de Recerca i Estudis Avancats (ICREA), Barcelona, Spain (Aloy); and the Centro Nacional de Analisis Genomico (CNAG), Barcelona, Spain (Bayes)
J Psychiatry Neurosci
2019
44: 350-359
|
| 31018497 |
Carrasco M et al.:
Alterations of Mitochondrial Biology in the Oral Mucosa of Chilean Children with Autism Spectrum Disorder (ASD)
|
| 25418537 |
O'Roak BJ et al. et al.:
Recurrent de novo mutations implicate novel genes underlying simplex autism risk
Nat Commun
2014
5: 5595
|
| 30394313 |
Wang M et al.:
Alteration of gut microbiota-associated epitopes in children with autism spectrum disorders
Brain Behav. Immun.
2019
75: 192-199
|
| 29114925 |
Ishizuka K et al. et al.:
Possible involvement of a cell adhesion molecule, Migfilin, in brain development and pathogenesis of autism spectrum disorders
J. Neurosci. Res.
2018
96: 789-802
|
| 28262759 |
Goto M et al.:
Role of a circadian-relevant gene NR1D1 in brain development: possible involvement in the pathophysiology of autism spectrum disorders
Sci Rep
2017
7: 43945
|
| 24520327 |
Choi J et al.:
Autism associated gene, engrailed2, and flanking gene levels are altered in post-mortem cerebellum
PLoS ONE
2014
9
|
| 31323913 |
Rafi SK et al.:
High Functioning Autism with Missense Mutations in Synaptotagmin-Like Protein 4 (SYTL4) and Transmembrane Protein 187 (TMEM187) Genes: SYTL4- Protein Modeling, Protein-Protein Interaction, Expression Profiling and MicroRNA Studies
|
| 24493018 |
Chiocchetti AG et al.:
Glutamatergic candidate genes in autism spectrum disorder: an overview
J Neural Transm (Vienna)
2014
121: 1081-1106
|
| 28540026 |
author information missing
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Mol Autism
2017
8: 21
|
| 24158444 |
Chu BW et al.:
The E3 ubiquitin ligase UBE3C enhances proteasome processivity by ubiquitinating partially proteolyzed substrates
J Biol Chem
2013
288
|
| 35221709 |
author information missing
article information missing
|
| 15805158 |
author information missing
article information missing
|
| 11074872 |
Guidotti A et al.:
Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study
Arch. Gen. Psychiatry
2000
57: 1061-1069
|
| 17270400 |
Veldic M et al.:
Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder
Schizophr. Res.
2007
91: 51-61
|
| 19059449 |
Torres KC et al.:
The leukocytes expressing DARPP-32 are reduced in patients with schizophrenia and bipolar disorder.
Prog. Neuropsychopharmacol. Biol. Psychiatry
2009
33: 214-219
|
| 20368704 |
Williams HJ et al.:
Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder
Mol. Psychiatry
2011
16: 429-441
|
| 16924267 |
Severinsen JE et al.:
Evidence implicating BRD1 with brain development and susceptibility to both schizophrenia and bipolar affective disorder.
Mol. Psychiatry
2006
11: 1126-1138
|
| 16484223 |
Assmann EM et al.:
FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region
J. Biol. Chem.
2006
281: 9869-9881
|
| 20569643 |
Hope S et al.:
Osteoprotegerin levels in patients with severe mental disorders
J Psychiatry Neurosci
2010
35: 304-310
|
| 19754466 |
OBrien WT et al.:
Validating GSK3 as an in vivo target of lithium action.
Biochem. Soc. Trans.
2009
37: 1133-1138
|
| 21176028 |
Beech RD et al.:
Increased peripheral blood expression of electron transport chain genes in bipolar depression.
Bipolar Disord
2010
12: 813-824
|
| 20566748 |
Cataldo AM et al.:
Abnormalities in mitochondrial structure in cells from patients with bipolar disorder.
Am. J. Pathol.
2010
177: 575-585
|
| 17485607 |
Naydenov AV et al.:
Differences in lymphocyte electron transport gene expression levels between subjects with bipolar disorder and normal controls in response to glucose deprivation stress.
Arch. Gen. Psychiatry
2007
64: 555-564
|
| 20368511 |
Andreazza AC et al.:
Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder
Arch. Gen. Psychiatry
2010
67: 360-368
|
| 1728159 |
Dubovsky SL et al.:
Abnormal intracellular calcium ion concentration in platelets and lymphocytes of bipolar patients.
Am J Psychiatry
1992
149: 118-120
|
| 15737668 |
Munakata K et al.:
Mitochondrial DNA 3243A>G mutation and increased expression of LARS2 gene in the brains of patients with bipolar disorder and schizophrenia.
Biol. Psychiatry
2005
57: 525-532
|
| 14993118 |
Konradi C et al.:
Molecular evidence for mitochondrial dysfunction in bipolar disorder
Arch. Gen. Psychiatry
2004
61: 300-308
|
| 16696827 |
MacDonald ML et al.:
Decrease in creatine kinase messenger RNA expression in the hippocampus and dorsolateral prefrontal cortex in bipolar disorder.
Bipolar Disord
2006
8: 255-264
|
| 18191109 |
Shao L et al.:
Shared gene expression alterations in schizophrenia and bipolar disorder
Biol. Psychiatry
2008
64: 89-97
|
| 19350560 |
Kahler AK et al.:
Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples.
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2010
153B: 86-96
|
| 22428012 |
Li J et al.:
Lithium impacts on the amplitude and period of the molecular circadian clockwork
PLoS ONE
2012
7
|
| 22384149 |
McCarthy MJ et al.:
A survey of genomic studies supports association of circadian clock genes with bipolar disorder spectrum illnesses and lithium response
PLoS ONE
2012
7
|
| 11723175 |
Bezchlibnyk YB et al.:
Gene expression differences in bipolar disorder revealed by cDNA array analysis of post-mortem frontal cortex
J. Neurochem.
2001
79: 826-834
|
| 23231880 |
Manu P et al.:
Insulin secretion in patients receiving clozapine, olanzapine, quetiapine and risperidone
Schizophr. Res.
2013
143: 358-362
|
| 20591414 |
Mukherjee S et al.:
Knockdown of Clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior
Biol. Psychiatry
2010
68: 503-511
|
| 17259569 |
Varma MK et al.:
Life-threatening hyperglycemia and acidosis related to olanzapine: a case report and review of the literature
J Intensive Care Med
2007
22: 52-55
|
| 11673795 |
Kirov G et al.:
Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder
Mol. Psychiatry
2001
6: 671-677
|
| 21961650 |
Squassina A et al.:
Evidence for association of an ACCN1 gene variant with response to lithium treatment in Sardinian patients with bipolar disorder
Pharmacogenomics
2011
12: 1559-1569
|
| 20679588 |
Erk S et al.:
Brain function in carriers of a genome-wide supported bipolar disorder variant
Arch. Gen. Psychiatry
2010
67: 803-811
|
| 22831755 |
Meier S et al.:
Neuregulin 3 is associated with attention deficits in schizophrenia and bipolar disorder
Int. J. Neuropsychopharmacol.
2013
16: 549-556
|
| 21927946 |
Yamada K et al.:
Association study of the KCNJ3 gene as a susceptibility candidate for schizophrenia in the Chinese population
Hum. Genet.
2012
131: 443-451
|
| 22017219 |
Backlund L et al.:
Cognitive manic symptoms associated with the P2RX7 gene in bipolar disorder
Bipolar Disord
2011
13: 500-508
|
| 21738484 |
Smith EN et al.:
Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes
PLoS Genet.
2011
7
|
| 23437964 |
Gonzalez S et al.:
Suggestive evidence for association between L-type voltage-gated calcium channel (CACNA1C) gene haplotypes and bipolar disorder in Latinos: a family-based association study
Bipolar Disord
2013
15: 206-214
|
| 24114586 |
Weston-Green K et al.:
Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor
CNS Drugs
2013
27: 1069-1080
|
| 22472876 |
Ripke S et al.:
A mega-analysis of genome-wide association studies for major depressive disorder
Mol. Psychiatry
2013
18: 497-511
|
| 24461634 |
Finseth PI et al.:
Association analysis between suicidal behaviour and candidate genes of bipolar disorder and schizophrenia
J Affect Disord
2014
163: 110-114
|
| 23974872 |
Ripke S et al.:
Genome-wide association analysis identifies 13 new risk loci for schizophrenia
Nat. Genet.
2013
45: 1150-1159
|
| 23880959 |
Wolf C et al.:
CACNA1C genotype explains interindividual differences in amygdala volume among patients with schizophrenia
Eur Arch Psychiatry Clin Neurosci
2014
264: 93-102
|
| 15563509 |
Iwamoto K et al.:
Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis
Hum. Mol. Genet.
2005
14: 241-253
|
| 23070075 |
Green EK et al.:
Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample
Mol. Psychiatry
2013
18: 1302-1307
|
| 17486107 |
Baum AE et al.:
A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder
Mol. Psychiatry
2008
13: 197-207
|
| 15722956 |
Pickard BS et al.:
Candidate psychiatric illness genes identified in patients with pericentric inversions of chromosome 18
Psychiatr. Genet.
2005
15: 37-44
|
| 16733521 |
Borsotto M et al.:
PP2A-Bgamma subunit and KCNQ2 K+ channels in bipolar disorder
Pharmacogenomics J.
2007
7: 123-132
|
| 17678634 |
Cannon DM et al.:
Elevated serotonin transporter binding in major depressive disorder assessed using positron emission tomography and [11C]DASB; comparison with bipolar disorder
Biol. Psychiatry
2007
62: 870-877
|
| 31170425 |
Noroozi R et al.:
Glutamate receptor metabotropic 7 (GRM7) gene polymorphisms in mood disorders and attention deficit hyperactive disorder
Neurochem. Int.
2019
129
|
| 24348429 |
Kerner B et al.:
Rare Genomic Variants Link Bipolar Disorder with Anxiety Disorders to CREB-Regulated Intracellular Signaling Pathways
Front Psychiatry
2013
4: 154
|
| 12140780 |
Vawter MP et al.:
Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia
Mol. Psychiatry
2002
7: 571-578
|
| 19166596 |
Kripke DF et al.:
Circadian polymorphisms associated with affective disorders
J Circadian Rhythms
2009
7: 2
|
| 24039173 |
McGrath LM et al.:
Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2013
162B: 779-788
|
| 26848839 |
Davis KN et al.:
GAD2 Alternative Transcripts in the Human Prefrontal Cortex, and in Schizophrenia and Affective Disorders
PLoS ONE
2016
11
|
| 27350034 |
Pacifico R et al.:
Transcriptome sequencing implicates dorsal striatum-specific gene network, immune response and energy metabolism pathways in bipolar disorder
Mol. Psychiatry
2017
22: 441-449
|
| 24718920 |
Nurnberger JI Jr et al.:
Identification of pathways for bipolar disorder: a meta-analysis
JAMA Psychiatry
2014
71: 657-664
|
| 29628500 |
Lee SE et al.:
nArgBP2-SAPAP-SHANK, the core postsynaptic triad associated with psychiatric disorders
Exp. Mol. Med.
2018
50: 2
|
| 27890468 |
van Hulzen KJE et al. et al.:
Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis
Biol. Psychiatry
2017
82: 634-641
|
| 21382426 |
Iwamoto K et al.:
Survey of the effect of genetic variations on gene expression in human prefrontal cortex and its application to genetics of psychiatric disorders
Neurosci. Res.
2011
70: 238-242
|
| 20357757 |
Polter A et al.:
Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances
Neuropsychopharmacology
2010
35: 1761-1774
|
| 30149091 |
Corponi F et al.:
Genetic basis of psychopathological dimensions shared between schizophrenia and bipolar disorder
Prog. Neuropsychopharmacol. Biol. Psychiatry
2019
89: 23-29
|
| 30905121 |
Oral E et al.:
Evaluation of Endothelial Dysfunction in Bipolar Affective Disorders: Serum Endocan and Urotensin-II Levels
Clin Psychopharmacol Neurosci
2019
17: 211-221
|
| 21621268 |
Magno LA et al.:
Genetic variations in FOXO3A are associated with Bipolar Disorder without confering vulnerability for suicidal behavior
J Affect Disord
2011
133: 633-637
|
| 28463235 |
Scaini G et al.:
Perturbations in the apoptotic pathway and mitochondrial network dynamics in peripheral blood mononuclear cells from bipolar disorder patients
Transl Psychiatry
2017
7: e1111
|
| 32754070 |
Reponen EJ et al. et al.:
Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
Front Psychiatry
2020
11: 672
|
| 17258816 |
Lee BD et al. et al.:
Malic enzyme 2 and susceptibility to psychosis and mania
Psychiatry Res
2007
150: 1-11
|
| 18357389 |
Lee SJ et al.:
Activation of matrix metalloproteinase-9 by TNF-alpha in human urinary bladder cancer HT1376 cells: the role of MAP kinase signaling pathways
Oncol. Rep.
2008
19: 1007-1013
|
| 21601006 |
Yoganathan TN et al.:
Integrin-linked kinase (ILK): a hot therapeutic target
Biochem. Pharmacol.
2000
60: 1115-1119
|
| 30121007 |
Chakravarthi BVSK et al. et al.:
A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression
Neoplasia
2018
20: 894-904
|
| 27189278 |
Kim WT et al. et al.:
Metabolic Pathway Signatures Associated with Urinary Metabolite Biomarkers Differentiate Bladder Cancer Patients from Healthy Controls
Yonsei Med. J.
2016
57: 865-871
|
| 32094233 |
Lokeshwar VB et al. et al.:
A Novel Splice Variant of HYAL-4 Drives Malignant Transformation and Predicts Outcome in Patients with Bladder Cancer
|
| 23866964 |
Dong LH et al.:
Histone deacetylase inhibitor potentiated the ability of MTOR inhibitor to induce autophagic cell death in Burkitt leukemia/lymphoma
J Hematol Oncol
2013
6: 53
|
| 20028864 |
Brown KA et al.:
Obesity and breast cancer: progress to understanding the relationship
Cancer Res.
2010
70: 4-7
|
| 19509226 |
Brown KA et al.:
Subcellular localization of cyclic AMP-responsive element binding protein-regulated transcription coactivator 2 provides a link between obesity and breast cancer in postmenopausal women
Cancer Res.
2009
69: 5392-5399
|
| 15766664 |
Kim RH et al.:
DJ-1, a novel regulator of the tumor suppressor PTEN.
Cancer Cell
2005
7: 263-273
|
| 11705844 |
Le Naour F et al.:
Proteomics-based identification of RS/DJ-1 as a novel circulating tumor antigen in breast cancer.
Clin. Cancer Res.
2001
7: 3328-3335
|
| 20971498 |
Berthier A et al.:
PINK1 displays tissue-specific subcellular location and regulates apoptosis and cell growth in breast cancer cells
Hum. Pathol.
2011
42: 75-87
|
| 16850246 |
Greenlee H et al.:
Variants in estrogen metabolism and biosynthesis genes and urinary estrogen metabolites in women with a family history of breast cancer
Breast Cancer Res. Treat.
2007
102: 111-117
|
| 1935184 |
Lessner MW et al.:
A student nurses experience in an ICU.
Crit Care Nurse
1991
11: 12
|
| 16361546 |
Cobleigh MA et al.:
Tumor gene expression and prognosis in breast cancer patients with 10 or more positive lymph nodes
Clin. Cancer Res.
2005
11: 8623-8631
|
| 11410592 |
Castro-Rivera E et al.:
Estrogen regulation of cyclin D1 gene expression in ZR-75 breast cancer cells involves multiple enhancer elements.
J. Biol. Chem.
2001
276
|
| 15870704 |
Lewandowski SA et al.:
Opposite effects of estrogen receptors alpha and beta on MCF-7 sensitivity to the cytotoxic action of TNF and p53 activity.
Oncogene
2005
24: 4789-4798
|
| 16328059 |
Li SY et al.:
Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in human breast cancer.
Oncol. Rep.
2006
15: 221-225
|
| 17519015 |
De Luca A et al.:
Important roles of multiple Sp1 binding sites and epigenetic modifications in the regulation of the methionine sulfoxide reductase B1 (MsrB1) promoter.
BMC Mol. Biol.
2007
8: 39
|
| 17510434 |
Lin Z et al.:
Novel estrogen receptor-alpha binding sites and estradiol target genes identified by chromatin immunoprecipitation cloning in breast cancer.
Cancer Res.
2007
67: 5017-5024
|
| 8195246 |
Krishnan V et al.:
Estrogen receptor-Sp1 complexes mediate estrogen-induced cathepsin D gene expression in MCF-7 human breast cancer cells.
J. Biol. Chem.
1994
269
|
| 9626663 |
Sun G et al.:
Estrogen-induced retinoic acid receptor alpha 1 gene expression: role of estrogen receptor-Sp1 complex.
Mol. Endocrinol.
1998
12: 882-890
|
| 12432273 |
Weinstein-Oppenheimer CR et al.:
The effects of beta-estradiol on Raf activity, cell cycle progression and growth factor synthesis in the MCF-7 breast cancer cell line.
Cancer Biol. Ther.
2002
1: 256-262
|
| 10733592 |
Perillo B et al.:
17beta-estradiol inhibits apoptosis in MCF-7 cells, inducing bcl-2 expression via two estrogen-responsive elements present in the coding sequence.
Mol. Cell. Biol.
2000
20: 2890-2901
|
| 24495551 |
Mehta D et al.:
Early predictive biomarkers for postpartum depression point to a role for estrogen receptor signaling
|
| 21655990 |
Hadad S et al.:
Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial.
Breast Cancer Res. Treat.
2011
128: 783-794
|
| 18714348 |
Martin KJ et al.:
Prognostic breast cancer signature identified from 3D culture model accurately predicts clinical outcome across independent datasets.
PLoS ONE
2008
3: E2994
|
| 21120602 |
Paruthiyil S et al.:
Estrogen receptor beta causes a G2 cell cycle arrest by inhibiting CDK1 activity through the regulation of cyclin B1, GADD45A, and BTG2
Breast Cancer Res. Treat.
2011
129: 777-784
|
| 17268063 |
Iso T et al.:
Modulation of the expression of bloom helicase by estrogenic agents.
Biol. Pharm. Bull.
2007
30: 266-271
|
| 19477925 |
Pedram A et al.:
Estrogen inhibits ATR signaling to cell cycle checkpoints and DNA repair.
Mol. Biol. Cell
2009
20: 3374-3389
|
| 17942748 |
Boverhof DR et al.:
Inhibition of estrogen-mediated uterine gene expression responses by dioxin
Mol. Pharmacol.
2008
73: 82-93
|
| 18949048 |
Wang C et al.:
Two estrogen response element sequences near the PCNA gene are not responsible for its estrogen-enhanced expression in MCF7 cells.
PLoS ONE
2008
3: E3523
|
| 16010982 |
Vani G et al.:
Effect of histone H1 on estrogen receptor status of human breast cancer MCF 7 cells.
Mol. Cell. Biochem.
2005
272: 151-155
|
| 19221498 |
Alimova IN et al.:
Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro.
Cell Cycle
2009
8: 909-915
|
| 14506733 |
Kawai H et al.:
Overexpression of histone deacetylase HDAC1 modulates breast cancer progression by negative regulation of estrogen receptor alpha
Int. J. Cancer
2003
107: 353-358
|
| 17062558 |
Zakikhani M et al.:
Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells.
Cancer Res.
2006
66
|
| 21185374 |
Englert NA et al.:
Persistent and non-persistent changes in gene expression result from long-term estrogen exposure of MCF-7 breast cancer cells.
J. Steroid Biochem. Mol. Biol.
2011
123: 140-150
|
| 12612058 |
Hodges LC et al.:
Tamoxifen functions as a molecular agonist inducing cell cycle-associated genes in breast cancer cells.
Mol. Cancer Res.
2003
1: 300-311
|
| 14605097 |
Wang DY et al.:
Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EEIG1.
Mol. Endocrinol.
2004
18: 402-411
|
| 16962797 |
Lee SU et al.:
Protein profiling and transcript expression levels of heat shock proteins in 17beta-estradiol-treated human MCF-7 breast cancer cells.
Cell Biol. Int.
2006
30: 983-991
|
| 17392432 |
Eakin CM et al.:
Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase.
Proc. Natl. Acad. Sci. U.S.A.
2007
104: 5794-5799
|
| 19887602 |
Ueki T et al.:
Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.
Cancer Res.
2009
69: 8752-8760
|
| 20501845 |
Zhao C et al.:
Genome-wide mapping of estrogen receptor-beta-binding regions reveals extensive cross-talk with transcription factor activator protein-1.
Cancer Res.
2010
70: 5174-5183
|
| 19434490 |
Treeck O et al.:
Estrogen receptor beta exerts growth-inhibitory effects on human mammary epithelial cells.
Breast Cancer Res. Treat.
2010
120: 557-565
|
| 17428314 |
Lin CY et al.:
Inhibitory effects of estrogen receptor beta on specific hormone-responsive gene expression and association with disease outcome in primary breast cancer
Breast Cancer Res.
2007
9: R25
|
| 10766163 |
Liu G et al.:
Estrogen receptor protects p53 from deactivation by human double minute-2.
Cancer Res.
2000
60: 1810-1814
|
| 15328371 |
Wang W et al.:
TAFII70 isoform-specific growth suppression correlates with its ability to complex with the GADD45a protein
Mol. Cancer Res.
2004
2: 442-452
|
| 17407970 |
Su T et al.:
Dip1 inhibits growth and gene transcription in MCF-7 breast cancer cells
J. Exp. Ther. Oncol.
2007
6: 117-127
|
| 10220405 |
Yarden RI et al.:
BRCA1 interacts with components of the histone deacetylase complex
Proc. Natl. Acad. Sci. U.S.A.
1999
96: 4983-4988
|
| 23288347 |
Yamada A et al.:
High expression of ATP-binding cassette transporter ABCC11 in breast tumors is associated with aggressive subtypes and low disease-free survival
Breast Cancer Res. Treat.
2013
137: 773-782
|
| 12878187 |
Gauthier ML et al.:
Protein kinase Calpha negatively regulates cell spreading and motility in MDA-MB-231 human breast cancer cells downstream of epidermal growth factor receptor
Biochem. Biophys. Res. Commun.
2003
307: 839-846
|
| 22279420 |
Mohibi S et al.:
Mouse models of estrogen receptor-positive breast cancer
J Carcinog
2011
10: 35
|
| 19754359 |
van der Veeken J et al.:
Crosstalk between epidermal growth factor receptor- and insulin-like growth factor-1 receptor signaling: implications for cancer therapy
Curr Cancer Drug Targets
2009
9: 748-760
|
| 18996184 |
Gaikwad NW et al.:
Evidence for NQO2-mediated reduction of the carcinogenic estrogen ortho-quinones
Free Radic. Biol. Med.
2009
46: 253-262
|
| 22386952 |
Pruthi S et al.:
Evaluation of serum estrogen-DNA adducts as potential biomarkers for breast cancer risk
J. Steroid Biochem. Mol. Biol.
2012
132: 73-79
|
| 16675129 |
Cavalieri E et al.:
Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention
Biochim. Biophys. Acta
2006
1766: 63-78
|
| 25110054 |
Do MT et al.:
Metformin suppresses CYP1A1 and CYP1B1 expression in breast cancer cells by down-regulating aryl hydrocarbon receptor expression
Toxicol. Appl. Pharmacol.
2014
280: 138-148
|
| 19995559 |
Vinothini G et al.:
Correlation of xenobiotic-metabolizing enzymes, oxidative stress and NFkappaB signaling with histological grade and menopausal status in patients with adenocarcinoma of the breast
Clin. Chim. Acta
2010
411: 368-374
|
| 23576571 |
Rodriguez M et al.:
CYP1A1 regulates breast cancer proliferation and survival
Mol. Cancer Res.
2013
11: 780-792
|
| 23733406 |
Goode GD et al.:
Knockdown of aberrantly upregulated aryl hydrocarbon receptor reduces tumor growth and metastasis of MDA-MB-231 human breast cancer cell line
Int. J. Cancer
2013
133: 2769-2780
|
| 14647449 |
Stoner M et al.:
Estrogen regulation of vascular endothelial growth factor gene expression in ZR-75 breast cancer cells through interaction of estrogen receptor alpha and SP proteins
Oncogene
2004
5: 1052-1063
|
| 23172368 |
Sotgia F et al.:
Mitochondria fuel breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells
Cell Cycle
2012
11: 4390-4401
|
| 24212942 |
Gupta N et al.:
beta-Catenin Is a Positive Regulator of Estrogen Receptor-alpha Function in Breast Cancer Cells
Cancers (Basel)
2011
3: 2990-3001
|
| 20838384 |
Kalra J et al.:
Suppression of Her2/neu expression through ILK inhibition is regulated by a pathway involving TWIST and YB-1
Oncogene
2010
29: 6343-6356
|
| 16785428 |
Bose R et al.:
Phosphoproteomic analysis of Her2/neu signaling and inhibition
Proc. Natl. Acad. Sci. U.S.A.
2006
103: 9773-9778
|
| 21402692 |
Mitra R et al.:
CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (+/-)-14,15-epoxyeicosatrienoic acid (EET)
J. Biol. Chem.
2011
286
|
| 21054339 |
Kim HG et al.:
Metformin inhibits P-glycoprotein expression via the NF-kappaB pathway and CRE transcriptional activity through AMPK activation
Br. J. Pharmacol.
2011
162: 1096-1108
|
| 21925487 |
Rudd LP et al.:
Enhanced glutathione depletion, protein adduct formation, and cytotoxicity following exposure to 4-hydroxy-2-nonenal (HNE) in cells expressing human multidrug resistance protein-1 (MRP1) together with human glutathione S-transferase-M1 (GSTM1)
Chem. Biol. Interact.
2011
194: 113-119
|
| 24667650 |
Sengupta D et al.:
ERRbeta signalling through FST and BCAS2 inhibits cellular proliferation in breast cancer cells
Br. J. Cancer
2014
110: 2144-2158
|
| 10608854 |
Li Z et al.:
IQGAP1 and calmodulin modulate E-cadherin function
J. Biol. Chem.
1999
274
|
| 25801958 |
Citro S et al.:
PI3K/mTOR mediate mitogen-dependent HDAC1 phosphorylation in breast cancer: a novel regulation of estrogen receptor expression
J Mol Cell Biol
2015
7: 132-142
|
| 21737670 |
Nakagawa M et al.:
Expression of p53, Ki-67, E-cadherin, N-cadherin and TOP2A in triple-negative breast cancer
Anticancer Res.
2011
31: 2389-2393
|
| 17875716 |
Miao ZH et al.:
Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses
Cancer Res.
2007
67: 8752-8761
|
| 20615467 |
Maeda T et al.:
Uptake transporter organic anion transporting polypeptide 1B3 contributes to the growth of estrogen-dependent breast cancer
J. Steroid Biochem. Mol. Biol.
2010
122: 180-185
|
| 24754247 |
Gozalpour E et al.:
Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3
Mol. Pharm.
2014
11: 1844-1855
|
| 19682730 |
Gupta PB et al.:
Identification of selective inhibitors of cancer stem cells by high-throughput screening
Cell
2009
138: 645-659
|
| 23730416 |
Hayman TJ et al.:
Competitive but Not Allosteric mTOR Kinase Inhibition Enhances Tumor Cell Radiosensitivity
Transl Oncol
2013
3: 355-362
|
| 24831777 |
Banerjee N et al.:
Expression of membrane transporters and metabolic enzymes involved in estrone-3-sulphate disposition in human breast tumour tissues
Breast Cancer Res. Treat.
2014
145: 647-661
|
| 26378621 |
Zhang W et al.:
Tris(2-chloroethyl)phosphate-induced cell growth arrest via attenuation of SIRT1-independent PI3K/Akt/mTOR pathway
J Appl Toxicol
2016
36: 914-924
|
| 21339306 |
Tiraby C et al.:
Estrogen-related receptor gamma promotes mesenchymal-to-epithelial transition and suppresses breast tumor growth
Cancer Res.
2011
71: 2518-2528
|
| 21566910 |
Vandewalle B et al.:
Effect of calcium on e-cadherin expression in breast-tumor cells
Int. J. Oncol.
1994
4: 181-185
|
| 18521741 |
Lanzino M et al.:
Insulin receptor substrate 1 modulates the transcriptional activity and the stability of androgen receptor in breast cancer cells
Breast Cancer Res. Treat.
2009
115: 297-306
|
| 22025613 |
Dong C et al.:
Regulation of alpha(2B)-adrenergic receptor-mediated extracellular signal-regulated kinase 1/2 (ERK1/2) activation by ADP-ribosylation factor 1
J. Biol. Chem.
2011
286
|
| 11072781 |
Jeng MH et al.:
Role of MAP kinase in the enhanced cell proliferation of long term estrogen deprived human breast cancer cells
Breast Cancer Res. Treat.
2000
62: 167-175
|
| 20353938 |
Ingermann AR et al.:
Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer
J. Biol. Chem.
2010
285
|
| 24304688 |
McGuirk S et al.:
PGC-1alpha supports glutamine metabolism in breast cancer
Cancer Metab
2013
1: 22
|
| 14500345 |
Oesterreich S et al.:
Estrogen-mediated down-regulation of E-cadherin in breast cancer cells
Cancer Res.
2003
63: 5203-5208
|
| 19943104 |
Jin W et al.:
UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer
Breast Cancer Res. Treat.
2010
123: 359-373
|
| 26621032 |
Holt SH et al.:
Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells
J. Cell. Sci.
2016
129: 155-165
|
| 23959881 |
Sohn YS et al.:
NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth
Proc. Natl. Acad. Sci. U.S.A.
2013
110
|
| 11525591 |
et al.:
|
| 23233354 |
Buffa L et al.:
Molecular mechanism of WW-domain binding protein-2 coactivation function in estrogen receptor signaling
IUBMB Life
2013
65: 76-84
|
| 21429623 |
Ordonez C et al.:
Gender differences in apolipoprotein D expression during aging and in Alzheimer disease
Neurobiol. Aging
2012
33: 433.e11-433.e20
|
| 28219369 |
McKinnon CM et al.:
The tumor suppressor RhoBTB1 controls Golgi integrity and breast cancer cell invasion through METTL7B
BMC Cancer
2017
17: 145
|
| 26887652 |
Gruel N et al.:
LIN7A is a major determinant of cell-polarity defects in breast carcinomas
Breast Cancer Res.
2016
18: 23
|
| 19901966 |
El-Tanani MK et al.:
Interferon-induced transmembrane 3 binds osteopontin in vitro: expressed in vivo IFITM3 reduced OPN expression
Oncogene
2010
29: 752-762
|
| 20696928 |
Clendening JW et al.:
Dysregulation of the mevalonate pathway promotes transformation
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 29655782 |
Miko E et al. et al.:
Lithocholic acid, a bacterial metabolite reduces breast cancer cell proliferation and aggressiveness
Biochim Biophys Acta Bioenerg
2018
1859: 958-974
|
| 23505378 |
Di Leva G et al. et al.:
Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status
PLoS Genet.
2013
9
|
| 30038517 |
Xia E et al.:
Synaptopodin-2 plays an important role in the metastasis of breast cancer via PI3K/Akt/mTOR pathway
Cancer Manag Res
2018
10: 1575-1583
|
| 12734209 |
Lam DD et al. et al.:
Leptin does not directly affect CNS serotonin neurons to influence appetite
Cell Metab.
2011
13: 584-591
|
| 28830874 |
O'Brien KM et al.:
Single-Nucleotide Polymorphisms in Vitamin D-Related Genes May Modify Vitamin D-Breast Cancer Associations
Cancer Epidemiol. Biomarkers Prev.
2017
26: 1761-1771
|
| 24008983 |
Xu X et al.:
Differential 12-O-Tetradecanoylphorbol-13-acetate-induced activation of rat mammary carcinoma susceptibility Fbxo10 variant promoters via a PKC-AP1 pathway
Mol. Carcinog.
2015
54: 134-147
|
| 28989055 |
Shu T et al.:
Down-regulation of HECTD3 by HER2 inhibition makes serous ovarian cancer cells sensitive to platinum treatment
Cancer Lett.
2017
411: 65-73
|
| 26795347 |
Bacci M et al.:
miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors
Cancer Res.
2016
76: 1615-1626
|
| 24374807 |
Marastoni S et al.:
EMILIN2 down-modulates the Wnt signalling pathway and suppresses breast cancer cell growth and migration
J Pathol
2014
232: 391-404
|
| 29968965 |
Li K et al.:
Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3beta/beta-catenin signaling pathway in breast cancer
Cancer Med
2018
7: 3875-3888
|
| 25436706 |
author information missing
Expression of thyroid-stimulating hormone receptor, octamer-binding transcription factor 4, and intracisternal A particle-promoted polypeptide in human breast cancer tissues
Horm Mol Biol Clin Investig
2012
9: 173-178
|
| 30335891 |
Kia V et al.:
Evaluation of exosomal miR-9 and miR-155 targeting PTEN and DUSP14 in highly metastatic breast cancer and their effect on low metastatic cells
J. Cell. Biochem.
2019
120: 5666-5676
|
| 28235484 |
Zhang L et al.:
Branched-chain amino acid transaminase 1 (BCAT1) promotes the growth of breast cancer cells through improving mTOR-mediated mitochondrial biogenesis and function
Biochem. Biophys. Res. Commun.
2017
486: 224-231
|
| 23001506 |
Godoy P et al.:
Interferon-inducible guanylate binding protein (GBP2) is associated with better prognosis in breast cancer and indicates an efficient T cell response
Breast Cancer
2014
21: 491-499
|
| 26640146 |
Park UH et al.:
ASXL2 promotes proliferation of breast cancer cells by linking ERalpha to histone methylation
Oncogene
2016
35: 3742-3752
|
| 23776679 |
Hwang MS et al.:
miR-221/222 targets adiponectin receptor 1 to promote the epithelial-to-mesenchymal transition in breast cancer
PLoS ONE
2013
8
|
| 31313837 |
Kang GJ et al.:
SARNP, a participant in mRNA splicing and export, negatively regulates E-cadherin expression via interaction with pinin
J. Cell. Physiol.
2020
235: 1543-1555
|
| 21602890 |
Park JH et al.:
Loss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1alpha mediated by the PTEN/PI3K/Akt pathway
Oncogene
2011
30: 4578-4589
|
| 31843902 |
Greene KS et al. et al.:
SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis
|
| 26389696 |
Okada M et al.:
Liganded ERalpha Stimulates the E3 Ubiquitin Ligase Activity of UBE3C to Facilitate Cell Proliferation
Mol Endocrinol
2015
29: 1646-1657
|
| 30360534 |
author information missing
article information missing
|
| 19946270 |
Veeriah S et al.:
Somatic mutations of the Parkinsons disease-associated gene PARK2 in glioblastoma and other human malignancies
Nat. Genet.
2010
42: 77-82
|
| 9842892 |
Piguet PF et al.:
TNF-induced enterocyte apoptosis in mice is mediated by the TNF receptor 1 and does not require p53
Eur. J. Immunol.
1998
28: 3499-3505
|
| 21602532 |
Cheng I et al.:
Type 2 diabetes risk variants and colorectal cancer risk: the Multiethnic Cohort and PAGE studies.
Gut
2011
60: 1703-1711
|
| 18172327 |
Gunter MJ et al.:
Insulin, insulin-like growth factor-I, endogenous estradiol, and risk of colorectal cancer in postmenopausal women.
Cancer Res.
2008
68: 329-337
|
| 21674030 |
Okyar A et al.:
Strain- and sex-dependent circadian changes in abcc2 transporter expression: implications for irinotecan chronotolerance in mouse ileum
PLoS ONE
2011
6
|
| 21931543 |
Ballesta A et al.:
A combined experimental and mathematical approach for molecular-based optimization of irinotecan circadian delivery
PLoS Comput. Biol.
2011
7
|
| 17591803 |
Koda M et al.:
Expression of the obesity hormone leptin and its receptor correlates with hypoxia-inducible factor-1 alpha in human colorectal cancer
Ann. Oncol.
2007
18: VI116-VI119
|
| 26124005 |
Wang Z et al.:
Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-kappaB signaling and suppressing cAMP-responsive element transcriptional activity
|
| 25165391 |
Zhu X et al.:
Calcium intake and ion transporter genetic polymorphisms interact in human colorectal neoplasia risk in a 2-phase study
J. Nutr.
2014
144: 1734-1741
|
| 11470825 |
Palmer HG et al.:
Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling
J. Cell Biol.
2001
154: 369-387
|
| 21514270 |
Kouchi Z et al.:
Phosphatidylinositol 5-phosphate 4-kinase type II beta is required for vitamin D receptor-dependent E-cadherin expression in SW480 cells
Biochem. Biophys. Res. Commun.
2011
408: 523-529
|
| 25559195 |
Takeda H et al.:
Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression
Nat. Genet.
2015
47: 142-150
|
| 25427913 |
Singh S et al.:
Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers
Adv. Exp. Med. Biol.
2015
815: 281-294
|
| 26579434 |
Ridlon JM et al.:
The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics
Acta Pharm Sin B
2015
5: 99-105
|
| 19051325 |
Shaffer JM et al.:
Promoter methylation blocks FES protein-tyrosine kinase gene expression in colorectal cancer
Genes Chromosomes Cancer
2009
48: 272-284
|
| 23945926 |
Setaffy L et al.:
Large serrated polyp with KRAS mutation in inflammatory bowel disease: a nondysplastic dysplasia-associated lesion or mass (DALM)? }, authors { names std { { name ml Setaffy L, affil str Institute of Pathology, Medical University, Graz, Austria
Endoscopy
2013
45: E235-E236
|
| 22921465 |
Gillespie E et al.:
Plasminogen activator inhibitor-1 is increased in colonic epithelial cells from patients with colitis-associated cancer
J Crohns Colitis
2013
7: 403-411
|
| 28454420 |
Yu B et al.:
Study of the expression and function of ACY1 in patients with colorectal cancer
Oncol Lett
2017
13: 2459-2464
|
| 25907800 |
Deng Z et al.:
Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis
Nat Commun
2015
6: 6956
|
| 10906131 |
Hinoi T et al.:
Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3 beta-dependent phosphorylation of beta-catenin and down-regulates beta-catenin
J. Biol. Chem.
2000
275
|
| 28051067 |
Jiao S et al.:
VGLL4 targets a TCF4-TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer
Nat Commun
2017
8: 14058
|
| 28098873 |
Hu CE et al.:
TRIM37 promotes epithelialmesenchymal transition in colorectal cancer
Mol Med Rep
2017
15: 1057-1062
|
| 30252597 |
Chen C et al.:
FOXD4 induces tumor progression in colorectal cancer by regulation of the SNAI3/CDH1 axis
|
| 31802911 |
Dong W et al.:
CARF, As An Oncogene, Promotes Colorectal Cancer Stemness By Activating ERBB Signaling Pathway
Onco Targets Ther
2019
12: 9041-9051
|
| 31730769 |
Holowatyj AN et al.:
Distinct Molecular Phenotype of Sporadic Colorectal Cancers Among Young Patients Based on Multiomics Analysis
Gastroenterology
2020
158: 1155-1158.e2
|
| 18216263 |
Wunderlich FT et al.:
Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 1297-1302
|
| 18932288 |
Lee CF et al.:
Distinct expression patterns in hepatitis B virus- and hepatitis C virus-infected hepatocellular carcinoma
World J. Gastroenterol.
2008
14: 6072-6077
|
| 12764143 |
Mottet D et al.:
Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells
J. Biol. Chem.
2003
278
|
| 9442036 |
Cha HH et al.:
Glucocorticoids stimulate p21 gene expression by targeting multiple transcriptional elements within a steroid responsive region of the p21waf1/cip1 promoter in rat hepatoma cells
J. Biol. Chem.
1998
273: 1998-2007
|
| 11741912 |
Adilakshmi T et al.:
Ribosomal protein S25 mRNA partners with MTF-1 and La to provide a p53-mediated mechanism for survival or death
J. Biol. Chem.
2002
277: 4147-4151
|
| 15611046 |
McMahon S et al.:
Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1: impact on the bioactivation of proproteins
J. Biol. Chem.
2005
280: 6561-6569
|
| 25796501 |
Wang W et al.:
Overexpression of AGGF1 is correlated with angiogenesis and poor prognosis of hepatocellular carcinoma
Med. Oncol.
2015
32: 131
|
| 24448241 |
Noh JH et al.:
HDAC2 provides a critical support to malignant progression of hepatocellular carcinoma through feedback control of mTORC1 and AKT
Cancer Res.
2014
74: 1728-1738
|
| 20099302 |
Soll C et al.:
Serotonin promotes tumor growth in human hepatocellular cancer
Hepatology
2010
51: 1244-1254
|
| 26052399 |
Ampuero J et al.:
Prevention of hepatocellular carcinoma by correction of metabolic abnormalities: Role of statins and metformin
World J Hepatol
2015
7: 1105-1111
|
| 20351271 |
Suzuki S et al.:
Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 7461-7466
|
| 24797434 |
Liu J et al.:
Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma
Oncotarget
2014
5: 2635-2647
|
| 25915584 |
author information missing
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
J. Clin. Invest.
2015
125: 2293-2306
|
| 25844758 |
author information missing
article information missing
|
| 29246230 |
Li M et al.:
Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling
Cell Commun. Signal
2017
15: 52
|
| 29088718 |
Liu P et al.:
Central role of mTORC1 downstream of YAP/TAZ in hepatoblastoma development
Oncotarget
2017
8
|
| 26311740 |
He C et al.:
MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway
Oncotarget
2015
6
|
| 30836988 |
Peng R et al. et al.:
Overexpression of RNF38 facilitates TGF-beta signaling by Ubiquitinating and degrading AHNAK in hepatocellular carcinoma
J. Exp. Clin. Cancer Res.
2019
38: 113
|
| 31105839 |
Kong D et al.:
EYA1 promotes cell migration and tumor metastasis in hepatocellular carcinoma
Am J Transl Res
2019
11: 2328-2338
|
| 29151969 |
Huang XQ et al.:
Overexpression of SMOC2 Attenuates the Tumorigenicity of Hepatocellular Carcinoma Cells and Is Associated With a Positive Postoperative Prognosis in Human Hepatocellular Carcinoma
J Cancer
2017
8: 3812-3827
|
| 30332648 |
Chan LH et al. et al.:
PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation
Cell Rep
2018
25: 690-701.e8
|
| 27608898 |
Cao F et al.:
PHACTR4 regulates proliferation, migration and invasion of human hepatocellular carcinoma by inhibiting IL-6/Stat3 pathway
Eur Rev Med Pharmacol Sci
2016
20: 3392-3399
|
| 25474138 |
Cui Y et al.:
AGK enhances angiogenesis and inhibits apoptosis via activation of the NF-kappaB signaling pathway in hepatocellular carcinoma
Oncotarget
2014
5
|
| 30561826 |
Lee D et al. et al.:
Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma
Hepatology
2019
69: 1768-1786
|
| 24425307 |
Jiang JH et al. et al.:
Clinical significance of the ubiquitin ligase UBE3C in hepatocellular carcinoma revealed by exome sequencing
Hepatology
2014
59: 2216-2227
|
| 32019286 |
author information missing
article information missing
|
| 35070304 |
author information missing
article information missing
|
| 25607821 |
author information missing
article information missing
|
| 20176206 |
Mauchley D et al.:
Modulation of growth in human esophageal adenocarcinoma cells by group IIa secretory phospholipase A(2)
J. Thorac. Cardiovasc. Surg.
2010
139: 591-599
|
| 29909415 |
Iguchi T et al. et al.:
Identification of UHRF2 as a Negative Regulator of Epithelial-Mesenchymal Transition and Its Clinical Significance in Esophageal Squamous Cell Carcinoma
Oncology
2018
95: 179-187
|
| 19946270 |
Veeriah S et al.:
Somatic mutations of the Parkinsons disease-associated gene PARK2 in glioblastoma and other human malignancies.
Nat. Genet.
2010
42: 77-82
|
| 23408368 |
Fan S et al.:
Overexpression of SLC7A7 predicts poor progression-free and overall survival in patients with glioblastoma
Med. Oncol.
2013
30: 384
|
| 12584187 |
Berdiev BK et al.:
Acid-sensing ion channels in malignant gliomas
J. Biol. Chem.
2003
278
|
| 20368557 |
Liu Y et al.:
Polymorphisms of LIG4, BTBD2, HMGA2, and RTEL1 genes involved in the double-strand break repair pathway predict glioblastoma survival
J. Clin. Oncol.
2010
28: 2467-2474
|
| 24582898 |
Li W et al.:
MUC4 modulates human glioblastoma cell proliferation and invasion by upregulating EGFR expression
Neurosci. Lett.
2014
566: 82-87
|
| 25898313 |
Daniele S et al.:
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells
Sci Rep
2015
5: 9956
|
| 25867026 |
Sesen J et al.:
Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response
PLoS ONE
2015
10
|
| 25222834 |
Cuperlovic-Culf M et al.:
Metabolic Effects of Known and Novel HDAC and SIRT Inhibitors in Glioblastomas Independently or Combined with Temozolomide
Metabolites
2014
4: 807-830
|
| 23625692 |
Sami A et al.:
Targeting the PI3K/AKT/mTOR signaling pathway in glioblastoma: novel therapeutic agents and advances in understanding
Tumour Biol.
2013
34: 1991-2002
|
| 15578701 |
Camphausen K et al.:
Enhancement of in vitro and in vivo tumor cell radiosensitivity by valproic acid
Int. J. Cancer
2005
114: 380-386
|
| 21362133 |
Shabason JE et al.:
Grand rounds at the National Institutes of Health: HDAC inhibitors as radiation modifiers, from bench to clinic
J. Cell. Mol. Med.
2011
15: 2735-2744
|
| 24418474 |
Choi EJ et al.:
Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases
BMC Cancer
2014
14: 17
|
| 20372862 |
Zhao N et al.:
Akt-mTOR signaling is involved in Notch-1-mediated glioma cell survival and proliferation
Oncol. Rep.
2010
23: 1443-1447
|
| 19827268 |
Jiang H et al.:
Resveratrol downregulates PI3K/Akt/mTOR signaling pathways in human U251 glioma cells
J. Exp. Ther. Oncol.
2009
8: 25-33
|
| 18772890 |
author information missing
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Nature
2008
455: 1061-1068
|
| 15143086 |
Chakravarti A et al.:
The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas
J. Clin. Oncol.
2004
22: 1926-1933
|
| 24096582 |
Szeliga M et al.:
Silencing of GLS and overexpression of GLS2 genes cooperate in decreasing the proliferation and viability of glioblastoma cells
Tumour Biol.
2014
35: 1855-1862
|
| 24276018 |
Martin-Rufian M et al.:
Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells
J. Mol. Med.
2014
92: 277-290
|
| 25284789 |
Takai H et al.:
5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex
Cell Rep
2014
9: 48-60
|
| 28534507 |
Zhu C et al.:
CECR1-mediated cross talk between macrophages and vascular mural cells promotes neovascularization in malignant glioma
Oncogene
2017
36: 5356-5368
|
| 22992974 |
Zadran S et al.:
ENTPD5-mediated modulation of ATP results in altered metabolism and decreased survival in gliomablastoma multiforme
Tumour Biol.
2012
33: 2411-2421
|
| 30552850 |
Wang Y et al.:
Myosin Heavy Chain 10 (MYH10) Gene Silencing Reduces Cell Migration and Invasion in the Glioma Cell Lines U251, T98G, and SHG44 by Inhibiting the Wnt/beta-Catenin Pathway
Med. Sci. Monit.
2018
24: 9110-9119
|
| 22740028 |
Anic GM et al.:
An exploratory analysis of common genetic variants in the vitamin D pathway including genome-wide associated variants in relation to glioma risk and outcome
Cancer Causes Control
2012
23: 1443-1449
|
| 26152360 |
Seong MW et al.:
Deleterious c-Cbl Exon Skipping Contributes to Human Glioma
Neoplasia
2015
17: 518-524
|
| 19519315 |
Chien J et al.:
HtrA serine proteases as potential therapeutic targets in cancer
Curr Cancer Drug Targets
2009
9: 451-468
|
| 15341671 |
Cangul H et al.:
Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers
BMC Genet.
2004
5: 27
|
| 23661552 |
Hollstein PE et al.:
Identifying the Ubiquitin Ligase complex that regulates the NF1 tumor suppressor and Ras
Cancer Discov
2013
3: 880-893
|
| 25088200 |
Gurgis FM et al.:
The p38-MK2-HuR pathway potentiates EGFRvIII-IL-1beta-driven IL-6 secretion in glioblastoma cells
Oncogene
2015
34: 2934-2942
|
| 26677976 |
Ohtsu N et al.:
Eva1 Maintains the Stem-like Character of Glioblastoma-Initiating Cells by Activating the Noncanonical NF-kappaB Signaling Pathway
Cancer Res.
2016
76: 171-181
|
| 29937354 |
Pavlyukov MS et al. et al.:
Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors
Cancer Cell
2018
34: 119-135.e10
|
| 27329597 |
Mao XG et al. et al.:
Hypoxia upregulates HIG2 expression and contributes to bevacizumab resistance in glioblastoma
Oncotarget
2016
7
|
| 29977365 |
Chen X et al.:
Knockdown of RWD domain containing 3 inhibits the malignant phenotypes of glioblastoma cells via inhibition of phosphoinositide 3-kinase/protein kinase B signaling
Exp Ther Med
2018
16: 384-393
|
| 18398573 |
Scrideli CA et al.:
Gene expression profile analysis of primary glioblastomas and non-neoplastic brain tissue: identification of potential target genes by oligonucleotide microarray and real-time quantitative PCR
J. Neurooncol.
2008
88: 281-291
|
| 26993504 |
D'Asti E et al.:
Extracellular Vesicles in Brain Tumor Progression
Cell. Mol. Neurobiol.
2016
36: 383-407
|
| 22843679 |
author information missing
article information missing
|
| 24606203 |
Blank AE et al.:
Tumour necrosis factor receptor superfamily member 9 (TNFRSF9) is up-regulated in reactive astrocytes in human gliomas
Neuropathol. Appl. Neurobiol.
2015
41: e56-e67
|
| 30863117 |
Wu R et al.:
Downregulation of KLF13 through DNMT1-mediated hypermethylation promotes glioma cell proliferation and invasion
Onco Targets Ther
2019
12: 1509-1520
|
| 28551850 |
Zhang J et al.:
MicroRNA-211 expression is down-regulated and associated with poor prognosis in human glioma
J. Neurooncol.
2017
133: 553-559
|
| 28116547 |
Seo SB et al.:
14-3-3beta Depletion Drives a Senescence Program in Glioblastoma Cells Through the ERK/SKP2/p27 Pathway
Mol. Neurobiol.
2018
55: 1259-1270
|
| 24065186 |
Gong F et al.:
14-3-3beta regulates the proliferation of glioma cells through the GSK3beta/beta-catenin signaling pathway
Oncol. Rep.
2013
30: 2976-2982
|
| 26976975 |
Kolodziej MA et al.:
NDRG2 and NDRG4 Expression Is Altered in Glioblastoma and Influences Survival in Patients with MGMT-methylated Tumors
Anticancer Res.
2016
36: 887-897
|
| 30514230 |
Li L et al.:
EGF/EGFR upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence
BMC Cancer
2018
18: 1215
|
| 27572852 |
Li Y et al.:
Identification of hub genes and regulatory factors of glioblastoma multiforme subgroups by RNA-seq data analysis
Int. J. Mol. Med.
2016
38: 1170-1178
|
| 24612214 |
Clara CA et al.:
Angiogenesis and expression of PDGF-C, VEGF, CD105 and HIF-1alpha in human glioblastoma
Neuropathology
2014
34: 343-352
|
| 31605013 |
Ji J et al. et al.:
PMEPA1 isoform a drives progression of glioblastoma by promoting protein degradation of the Hippo pathway kinase LATS1
Oncogene
2020
39: 1125-1139
|
| 29966699 |
Panagopoulos AT et al.:
The prostanoid pathway contains potential prognostic markers for glioblastoma
Prostaglandins Other Lipid Mediat.
2018
137: 52-62
|
| 30590814 |
Zhi T et al.:
ECT2/PSMD14/PTTG1 axis promotes the proliferation of glioma through stabilizing E2F1
Neuro-oncology
2019
21: 462-473
|
| 16685397 |
Genkai N et al.:
Increased expression of pituitary tumor-transforming gene (PTTG)-1 is correlated with poor prognosis in glioma patients
Oncol. Rep.
2006
15: 1569-1574
|
| 28244851 |
et al.:
GGNBP2 Suppresses the Proliferation, Invasion, and Migration of Human Glioma Cells
Oncol Res
2017
25: 831-842
|
| 31277942 |
Yu H et al.:
RCC2 promotes proliferation and radio-resistance in glioblastoma via activating transcription of DNMT1
Biochem. Biophys. Res. Commun.
2019
516: 999-1006
|
| 32594352 |
Bhawe K et al.:
Nuclear Respiratory Factor 1 (NRF1) Transcriptional Activity-Driven Gene Signature Association with Severity of Astrocytoma and Poor Prognosis of Glioblastoma
Mol. Neurobiol.
2020
57: 3827-3845
|
| 25982477 |
Cao L et al.:
Down-regulation of 14-3-3beta exerts anti-cancer effects through inducing ER stress in human glioma U87 cells: Involvement of CHOP-Wnt pathway
Biochem. Biophys. Res. Commun.
2015
462: 389-395
|
| 27491149 |
author information missing
[EXPRESSION OF PFKFB, HK2, NAMPT, TSPAN13 AND HSPB8 GENES IN PEDIATRIC GLIOMA]
|
| 30628650 |
Yang H et al.:
A thirteengene set efficiently predicts the prognosis of glioblastoma
Mol Med Rep
2019
19: 1613-1621
|
| 29655792 |
He Z et al.:
Long non-coding RNA UCA1/miR-182/PFKFB2 axis modulates glioblastoma-associated stromal cells-mediated glycolysis and invasion of glioma cells
Biochem. Biophys. Res. Commun.
2018
500: 569-576
|
| 32436804 |
Liu Z et al.:
Abnormally high expression of HOXA2 as an independent factor for poor prognosis in glioma patients
Cell Cycle
2020
19: 1632-1640
|
| 31807002 |
Chang M et al.:
MicroRNA-769-5p Promotes The Growth Of Glioma Cells By Targeting Lysine Methyltransferase 2A
Onco Targets Ther
2019
12: 9177-9187
|
| 31938310 |
Li H et al.:
LOXL1 regulates cell apoptosis and migration in human neuroglioma U87 and U251 cells via Wnt/beta-catenin signaling
Int J Clin Exp Pathol
2018
11: 2032-2037
|
| 26164207 |
Roy A et al.:
Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
Oncotarget
2015
6
|
| 28297667 |
Cui Q et al. et al.:
m(6)A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
Cell Rep
2017
18: 2622-2634
|
| 31494931 |
Li Y et al.:
N-acetylglucosaminyltransferase I promotes glioma cell proliferation and migration through increasing the stability of the glucose transporter GLUT1
FEBS Lett.
2020
594: 358-366
|
| 15517309 |
Knobbe CB et al.:
Mutation analysis of the Ras pathway genes NRAS, HRAS, KRAS and BRAF in glioblastomas
Acta Neuropathol.
2004
108: 467-470
|
| 24861879 |
Shi Z et al. et al.:
MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras
Neuro-oncology
2014
16: 1341-1353
|
| 26632666 |
Duan S et al. et al.:
PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype
Nat Commun
2015
6: 10068
|
| 31433208 |
Hu G et al.:
Prognostic Markers Identification in Glioma by Gene Expression Profile Analysis
J. Comput. Biol.
2020
27: 81-90
|
| 32518375 |
Yu S et al.:
GBP2 enhances glioblastoma invasion through Stat3/fibronectin pathway
Oncogene
2020
39: 5042-5055
|
| 30887657 |
author information missing
article information missing
|
| 31636512 |
Wang R et al.:
Histone methyltransferase SUV39H2 regulates cell growth and chemosensitivity in glioma via regulation of hedgehog signaling
Cancer Cell Int
2019
19: 269
|
| 10917203 |
Mohr L et al.:
Rabbit cytochrome P450 4B1: A novel prodrug activating gene for pharmacogene therapy of hepatocellular carcinoma
Cancer Gene Ther
2000
7: 1008-1014
|
| 31803734 |
author information missing
article information missing
|
| 24726753 |
author information missing
article information missing
|
| 29079956 |
author information missing
article information missing
|
| 26119730 |
LaGory EL et al.:
Suppression of PGC-1alpha Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma
Cell Rep
2015
12: 116-127
|
| 25344677 |
Guo Z et al.:
KCNJ1 inhibits tumor proliferation and metastasis and is a prognostic factor in clear cell renal cell carcinoma
Tumour Biol.
2015
36: 1251-1259
|
| 25945836 |
Lucarelli G et al.:
Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma
Oncotarget
2015
6
|
| 31788053 |
Kotulak-Chrzaszcz A et al.:
Expression of the Sonic Hedgehog pathway components in clear cell renal cell carcinoma
Oncol Lett
2019
18: 5801-5810
|
| 25473003 |
Shou Y et al.:
A Five-Gene Hedgehog Signature Developed as a Patient Preselection Tool for Hedgehog Inhibitor Therapy in Medulloblastoma
|
| 23900540 |
Holtz AM et al.:
Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning
Development
2013
140: 3423-3434
|
| 9931336 |
Smyth I et al.:
Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32
Hum. Mol. Genet.
1999
8: 291-297
|
| 19833601 |
Brugieres L et al.:
Incomplete penetrance of the predisposition to medulloblastoma associated with germ-line SUFU mutations
J. Med. Genet.
2010
47: 142-144
|
| 28276480 |
Coni S et al. et al.:
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma
Sci Rep
2017
7: 44079
|
| 19584924 |
Lu Y et al.:
Amplification and overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma
PLoS ONE
2009
4: e6159
|
| 31541170 |
Robinson MH et al.:
Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma
Sci Rep
2019
9: 13611
|
| 26446920 |
Malhotra A et al.:
Sonic Hedgehog Signaling Drives Mitochondrial Fragmentation by Suppressing Mitofusins in Cerebellar Granule Neuron Precursors and Medulloblastoma
Mol. Cancer Res.
2016
14: 114-124
|
| 30810905 |
Vriend J et al.:
Differential Expression of Genes for Ubiquitin Ligases in Medulloblastoma Subtypes
Cerebellum
2019
18: 469-488
|
| 30227871 |
Callegari K et al.:
Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration
Cell Commun. Signal
2018
16: 60
|
| 22525724 |
Li W et al.:
SBF-1, a synthetic steroidal glycoside, inhibits melanoma growth and metastasis through blocking interaction between PDK1 and AKT3
Biochem. Pharmacol.
2012
84: 172-181
|
| 16778180 |
Furuta J et al.:
Silencing of Peroxiredoxin 2 and aberrant methylation of 33 CpG islands in putative promoter regions in human malignant melanomas
Cancer Res.
2006
66: 6080-6086
|
| 23537197 |
Pena-Chilet M et al.:
Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population
BMC Cancer
2013
13: 160
|
| 23431193 |
Posch C et al. et al.:
Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo
Proc Natl Acad Sci U S A
2013
110: 4015-4020
|
| 21537389 |
author information missing
A polymorphism in the glucokinase gene that raises plasma fasting glucose, rs1799884, is associated with diabetes mellitus and prostate cancer: findings from a population-based, case-control study (the ProtecT study)
Int J Mol Epidemiol Genet
2010
1: 175-183
|
| 17603485 |
Gudmundsson J et al.:
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
Nat. Genet.
2007
39: 977-983
|
| 20203524 |
Pierce BL et al.:
Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk.
Hum. Hered.
2010
69: 193-201
|
| 18835745 |
Ma J et al.:
Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis.
Lancet Oncol.
2008
9: 1039-1047
|
| 15059908 |
Chesire DR et al.:
Identification of aryl hydrocarbon receptor as a putative Wnt/beta-catenin pathway target gene in prostate cancer cells
Cancer Res.
2004
64: 2523-2533
|
| 20807808 |
Zhu ML et al.:
Tubulin-targeting chemotherapy impairs androgen receptor activity in prostate cancer
Cancer Res.
2010
70: 7992-8002
|
| 15598662 |
Hodgson MC et al.:
The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists
J. Biol. Chem.
2005
280: 6511-6519
|
| 19021144 |
Mamaeva OA et al.:
Calcium/calmodulin-dependent kinase II regulates notch-1 signaling in prostate cancer cells
J. Cell. Biochem.
2009
106: 25-32
|
| 18519708 |
Montgomery RB et al.:
Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth
Cancer Res.
2008
68: 4447-4454
|
| 18384941 |
Ummanni R et al.:
Prohibitin identified by proteomic analysis of prostate biopsies distinguishes hyperplasia and cancer
Cancer Lett.
2008
266: 171-185
|
| 18519708 |
Montgomery RB et al.:
Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth
Cancer Res.
2008
11: 4447-4454
|
| 24717169 |
Carter RC et al.:
Effects of prenatal alcohol exposure on testosterone and pubertal development
Alcohol. Clin. Exp. Res.
2014
38: 1671-1679
|
| 24779401 |
Makarevic J et al.:
Cross-communication between histone H3 and H4 acetylation and Akt-mTOR signalling in prostate cancer cells
J. Cell. Mol. Med.
2014
18: 1460-1466
|
| 23687346 |
Fendt SM et al.:
Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism
Cancer Res.
2013
73: 4429-4438
|
| 26002551 |
Loubiere C et al.:
Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells
Oncotarget
2015
6
|
| 26847995 |
author information missing
article information missing
|
| 22842514 |
Hafiz S et al.:
Expression of melanocortin receptors in human prostate cancer cell lines: MC2R activation by ACTH increases prostate cancer cell proliferation
Int. J. Oncol.
2012
41: 1373-1380
|
| 29669796 |
Liu H et al. et al.:
PRDM4 mediates YAP-induced cell invasion by activating leukocyte-specific integrin beta2 expression
|
| 19906297 |
Filleur S et al.:
INTS6/DICE1 inhibits growth of human androgen-independent prostate cancer cells by altering the cell cycle profile and Wnt signaling
Cancer Cell Int.
2009
9: 28
|
| 23272133 |
Lin X et al. et al.:
MiR-155 Enhances Insulin Sensitivity by Coordinated Regulation of Multiple Genes in Mice
PLoS Genet.
2016
12
|
| 30774776 |
Trujillo-Caceres SJ et al.:
Contribution of MSMB promoter region gene polymorphism to early-onset prostate cancer risk in Mexican males
Oncotarget
2019
10: 738-748
|
| 22531786 |
Chng KR et al.:
A transcriptional repressor co-regulatory network governing androgen response in prostate cancers
EMBO J.
2012
31: 2810-2823
|
| 14766760 |
Curtin JF et al.:
JNK regulates HIPK3 expression and promotes resistance to Fas-mediated apoptosis in DU 145 prostate carcinoma cells
J. Biol. Chem.
2004
279
|
| 32872192 |
Dominska K et al.:
The Impact of Ang-(1-9) and Ang-(3-7) on the Biological Properties of Prostate Cancer Cells by Modulation of Inflammatory and Steroidogenesis Pathway Genes
|
| 14583493 |
MacKeigan JP et al.:
Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha.
Cancer Res.
2003
63: 6928-6934
|
| 15976810 |
Shinbo Y et al.:
Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities.
Cell Death Differ.
2006
13: 96-108
|
| 17237272 |
Oguri T et al.:
MRP8/ABCC11 directly confers resistance to 5-fluorouracil
Mol. Cancer Ther.
2007
6: 122-127
|
| 22544838 |
Ware JJ et al.:
From men to mice: CHRNA5/CHRNA3, smoking behavior and disease
Nicotine Tob. Res.
2012
14: 1291-1299
|
| 18978787 |
Wang Y et al.:
Common 5p15.33 and 6p21.33 variants influence lung cancer risk
Nat. Genet.
2008
40: 1407-1409
|
| 21559498 |
Wang Y et al.:
Chromosome 15q25 (CHRNA3-CHRNA5) variation impacts indirectly on lung cancer risk
PLoS ONE
2011
6
|
| 19654303 |
Broderick P et al.:
Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study
Cancer Res.
2009
69: 6633-6641
|
| 23872218 |
Flora AV et al.:
Functional characterization of SNPs in CHRNA3/B4 intergenic region associated with drug behaviors
Brain Res.
2013
1529: 1-15
|
| 25884493 |
Etokebe GE et al.:
Association of the FAM46A gene VNTRs and BAG6 rs3117582 SNP with non small cell lung cancer (NSCLC) in Croatian and Norwegian populations
PLoS ONE
2015
10
|
| 20081861 |
Houghton AM et al.:
Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth
Nat. Med.
2010
16: 219-223
|
| 23420440 |
Chou CH et al.:
SCUBE3 regulation of early lung cancer angiogenesis and metastatic progression
Clin. Exp. Metastasis
2013
30: 741-752
|
| 21441952 |
Wu YY et al.:
SCUBE3 is an endogenous TGF-beta receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer
Oncogene
2011
30: 3682-3693
|
| 23318453 |
Tsai HY et al.:
Endoplasmic reticulum ribosome-binding protein 1 (RRBP1) overexpression is frequently found in lung cancer patients and alleviates intracellular stress-induced apoptosis through the enhancement of GRP78
Oncogene
2013
32: 4921-4931
|
| 26140362 |
Goswami MT et al.:
Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer
Oncotarget
2015
6
|
| 24452750 |
Haigl B et al.:
Expression of microRNA-21 in non-small cell lung cancer tissue increases with disease progression and is likely caused by growth conditional changes during malignant transformation
Int. J. Oncol.
2014
44: 1325-1334
|
| 30210621 |
Jin C et al.:
Loss of UHRF2 Is Associated With Non-small Cell Lung Carcinoma Progression
J Cancer
2018
9: 2994-3005
|
| 26622902 |
Li S et al.:
Sequencing study on familial lung squamous cancer
Oncol Lett
2015
10: 2634-2638
|
| 31278886 |
Wu Y et al.:
Uridine-cytidine kinase 2 (UCK2): A potential diagnostic and prognostic biomarker for lung cancer
Cancer Sci.
2019
110: 2734-2747
|
| 31253869 |
Saigi M et al.:
Determinants of immunological evasion and immunocheckpoint inhibition response in non-small cell lung cancer: the genetic front
Oncogene
2019
38: 5921-5932
|
| 20473924 |
Schulte JH et al.:
Accurate prediction of neuroblastoma outcome based on miRNA expression profiles
Int. J. Cancer
2010
127: 2374-2385
|
| 10803465 |
Eggert A et al.:
Molecular dissection of TrkA signal transduction pathways mediating differentiation in human neuroblastoma cells
Oncogene
2000
19: 2043-2051
|
| 15322108 |
Bryan B et al.:
GEFT, a Rho family guanine nucleotide exchange factor, regulates neurite outgrowth and dendritic spine formation
J. Biol. Chem.
2004
279
|
| 18413728 |
Molenaar JJ et al.:
Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma
Cancer Res.
2008
68: 2599-2609
|
| 24912852 |
De Antonellis P et al.:
Early targets of miR-34a in neuroblastoma
Mol. Cell Proteomics
2014
13: 2114-2131
|
| 22331471 |
Virden RA et al.:
Characterization of critical domains within the tumor suppressor CASZ1 required for transcriptional regulation and growth suppression
Mol. Cell. Biol.
2012
32: 1518-1528
|
| 23939472 |
Wang JL et al.:
Novel genes FAM134C, C3orf10 and ENOX1 are regulated by NRF-1 and differentially regulate neurite outgrowth in neuroblastoma cells and hippocampal neurons
Gene
2013
529: 7-15
|
| 16631738 |
Shim KS et al.:
Bach2 is involved in neuronal differentiation of N1E-115 neuroblastoma cells
Exp. Cell Res.
2006
312: 2264-2278
|
| 22906418 |
Sung PJ et al.:
Identification and characterisation of STMN4 and ROBO2 gene involvement in neuroblastoma cell differentiation
Cancer Lett.
2013
328: 168-175
|
| 28115010 |
Haile Y et al.:
Rab32 connects ER stress to mitochondrial defects in multiple sclerosis
J Neuroinflammation
2017
14: 19
|
| 28605984 |
Gil-Ibanez P et al.:
Is the Intrinsic Genomic Activity of Thyroxine Relevant In Vivo? Effects on Gene Expression in Primary Cerebrocortical and Neuroblastoma Cells
Thyroid
2017
27: 1092-1098
|
| 32599975 |
author information missing
article information missing
|
| 19651775 |
Mascarenhas JB et al.:
PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene
J. Biol. Chem.
2009
284
|
| 19375425 |
Li D et al.:
Antidiabetic therapies affect risk of pancreatic cancer.
Gastroenterology
2009
137: 482-488
|
| 22590527 |
Hou J et al.:
FKBP5 as a selection biomarker for gemcitabine and Akt inhibitors in treatment of pancreatic cancer
PLoS ONE
2012
7
|
| 23803693 |
Nair V et al.:
Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors
Carcinogenesis
2013
12: 2870-2879
|
| 26164081 |
Cohen R et al.:
Targeting cancer cell metabolism in pancreatic adenocarcinoma
Oncotarget
2015
19
|
| 21448452 |
Vareed SK et al. et al.:
Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma
PLoS ONE
2011
6
|
| 26797144 |
Lachaud C et al.:
Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability
Science
2016
351: 846-849
|
| 18784743 |
Nishioka C et al.:
Blockade of mTOR signaling potentiates the ability of histone deacetylase inhibitor to induce growth arrest and differentiation of acute myelogenous leukemia cells
Leukemia
2008
22: 2159-2168
|
| 22932805 |
Khandanpour C et al.:
The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice
Blood
2012
120: 4006-4017
|
| 16330448 |
author information missing
The prognostic value of cN-II and cN-III enzymes in adult acute myeloid leukemia
Haematologica
2005
90: 1699-1701
|
| 24973361 |
Micol JB et al. et al.:
Frequent ASXL2 mutations in acute myeloid leukemia patients with t(8;21)/RUNX1-RUNX1T1 chromosomal translocations
Blood
2014
124: 1445-1449
|
| 25306901 |
Inoue D et al. et al.:
SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS
Leukemia
2015
29: 847-857
|
| 30367089 |
Saika M et al.:
ASXL1 and SETBP1 mutations promote leukaemogenesis by repressing TGFbeta pathway genes through histone deacetylation
Sci Rep
2018
8: 15873
|
| 32724426 |
author information missing
article information missing
|
| 19996286 |
Lin LF et al.:
ZBRK1 acts as a metastatic suppressor by directly regulating MMP9 in cervical cancer.
Cancer Res.
2010
70: 192-201
|
| 29627439 |
Wang F et al.:
MiR-155-5p inhibits PDK1 and promotes autophagy via the mTOR pathway in cervical cancer
Int. J. Biochem. Cell Biol.
2018
99: 91-99
|
| 31897153 |
Han B et al.:
FNDC3B is associated with ER stress and poor prognosis in cervical cancer
Oncol Lett
2020
19: 406-414
|
| 14985505 |
Shaw RJ et al.:
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.
Proc. Natl. Acad. Sci. U.S.A.
2004
101: 3329-3335
|
| 12771025 |
Li J et al.:
AMPK-beta1 subunit is a p53-independent stress responsive protein that inhibits tumor cell growth upon forced expression
Carcinogenesis
2003
24: 827-834
|
| 19885556 |
Kim YC et al.:
Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN.
Int. J. Oncol.
2009
35: 1331-1341
|
| 20510502 |
Ren H et al.:
DJ-1, a cancer and Parkinsons disease associated protein, regulates autophagy through JNK pathway in cancer cells
Cancer Lett.
2010
297: 101-108
|
| 21912508 |
Braun S et al.:
The link between the metabolic syndrome and cancer
Int. J. Biol. Sci.
2011
7: 1003-1015
|
| 19564453 |
Libby G et al.:
New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes.
Diabetes Care
2009
32: 1620-1625
|
| 20947488 |
Decensi A et al.:
Metformin and cancer risk in diabetic patients: a systematic review and meta-analysis.
Cancer Prev Res (Phila)
2010
3: 1451-1461
|
| 19918015 |
Landman GW et al.:
Metformin associated with lower cancer mortality in type 2 diabetes: ZODIAC-16.
Diabetes Care
2010
33: 322-326
|
| 19082520 |
Monami M et al.:
Sulphonylureas and cancer: a case-control study.
Acta Diabetol
2009
46: 279-284
|
| 16443869 |
Bowker SL et al.:
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin.
Diabetes Care
2006
29: 254-258
|
| 18006825 |
Dowling RJ et al.:
Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells.
Cancer Res.
2007
67
|
| 22132214 |
Jung JW et al.:
Metformin Represses Self-Renewal of the Human Breast Carcinoma Stem Cells via Inhibition of Estrogen Receptor-Mediated OCT4 Expression.
PLoS ONE
2011
6
|
| 18212742 |
Ben Sahra I et al.:
The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.
Oncogene
2008
27: 3576-3586
|
| 19822355 |
Cantrell LA et al.:
Metformin is a potent inhibitor of endometrial cancer cell proliferation--implications for a novel treatment strategy.
Gynecol. Oncol.
2010
116: 92-98
|
| 17447005 |
Isakovic A et al.:
Dual antiglioma action of metformin: cell cycle arrest and mitochondria-dependent apoptosis.
Cell. Mol. Life Sci.
2007
64: 1290-1302
|
| 19440038 |
Liu B et al.:
Metformin induces unique biological and molecular responses in triple negative breast cancer cells.
Cell Cycle
2009
8: 2031-2040
|
| 19491931 |
Chen W et al.:
Phenotypes and genotypes of insulin-like growth factor 1, IGF-binding protein-3 and cancer risk: evidence from 96 studies.
Eur. J. Hum. Genet.
2009
17: 1668-1675
|
| 18497064 |
Hontz AE et al.:
Expression of selected Aurora A kinase substrates in solely estrogen-induced ectopic uterine stem cell tumors in the Syrian hamster kidney.
Adv. Exp. Med. Biol.
2008
617: 411-418
|
| 22266860 |
Chuang JY et al.:
Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells
Oncogene
2012
31: 4946-4959
|
| 20679220 |
Ueda T et al.:
Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 11463832 |
Knauf U et al.:
Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2
Mol. Cell. Biol.
2001
21: 5500-5511
|
| 22392765 |
Hou J et al.:
Targeting Mnks for cancer therapy
Oncotarget
2012
3: 118-131
|
| 15345718 |
Legembre P et al.:
Identification of SNF1/AMP kinase-related kinase as an NF-kappaB-regulated anti-apoptotic kinase involved in CD95-induced motility and invasiveness
J. Biol. Chem.
2004
279
|
| 20458141 |
van de Sluis B et al.:
COMMD1 disrupts HIF-1alpha/beta dimerization and inhibits human tumor cell invasion
J. Clin. Invest.
2010
120: 2119-2130
|
| 20482850 |
Wu G et al.:
A human functional protein interaction network and its application to cancer data analysis
Genome Biol.
2010
11: R53
|
| 22259062 |
Peverelli E et al.:
Filamin-A is essential for dopamine d2 receptor expression and signaling in tumorous lactotrophs
J. Clin. Endocrinol. Metab.
2012
97: 967-977
|
| 12469206 |
Katoh M et al.:
Expression and regulation of WNT1 in human cancer: up-regulation of WNT1 by beta-estradiol in MCF-7 cells
Int. J. Oncol.
2003
22: 209-212
|
| 10572067 |
Fernandes AM et al.:
Dominance of ErbB-1 heterodimers in lung epithelial cells overexpressing ErbB-2. Both ErbB-1 and ErbB-2 contribute significantly to tumorigenicity
Am. J. Respir. Cell Mol. Biol.
1999
21: 701-709
|
| 10862525 |
Li DN et al.:
Polymorphisms in P450 CYP1B1 affect the conversion of estradiol to the potentially carcinogenic metabolite 4-hydroxyestradiol
Pharmacogenetics
2000
10: 343-353
|
| 15304487 |
Kouzmenko AP et al.:
Wnt/beta-catenin and estrogen signaling converge in vivo
J. Biol. Chem.
2004
279
|
| 21388974 |
author information missing
article information missing
|
| 17138652 |
Lehnes K et al.:
The effect of estradiol on in vivo tumorigenesis is modulated by the human epidermal growth factor receptor 2/phosphatidylinositol 3-kinase/Akt1 pathway
Endocrinology
2007
148: 1171-1180
|
| 17410209 |
Li J et al.:
CBP/p300 are bimodal regulators of Wnt signaling
EMBO J.
2007
26: 2284-2294
|
| 14749120 |
Clevers H et al.:
Wnt breakers in colon cancer
Cancer Cell
2004
5: 5-6
|
| 18172554 |
Zudaire E et al.:
The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancers
J. Clin. Invest.
2008
118: 640-650
|
| 21976023 |
Opitz CA et al.:
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
Nature
2011
478: 197-203
|
| 10329476 |
Kolla V et al.:
Upregulation of mineralocorticoid- and glucocorticoid-receptor gene expression by Sp-I
Mol. Cell Biol. Res. Commun.
1999
1: 44-47
|
| 19376845 |
Beedanagari SR et al.:
Resveratrol inhibits dioxin-induced expression of human CYP1A1 and CYP1B1 by inhibiting recruitment of the aryl hydrocarbon receptor complex and RNA polymerase II to the regulatory regions of the corresponding genes
Toxicol. Sci.
2009
110: 61-67
|
| 19018768 |
Choi H et al.:
Curcumin attenuates cytochrome P450 induction in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin by ROS-dependently degrading AhR and ARNT
Cancer Sci.
2008
99: 2518-2524
|
| 21878739 |
Terashima J et al.:
Induction of CYP1 family members under low-glucose conditions requires AhR expression and occurs through the nuclear translocation of AhR
Drug Metab Pharmacokinet
2011
26: 577-583
|
| 11279538 |
Lee YS et al.:
Role of NAD(P)H oxidase in the tamoxifen-induced generation of reactive oxygen species and apoptosis in HepG2 human hepatoblastoma cells
Cell Death Differ.
2000
7: 925-932
|
| 24049067 |
Garcia-Jimenez C et al.:
A new link between diabetes and cancer: enhanced WNT/beta-catenin signaling by high glucose
J Mol Endocrinol
2013
52: R51-R66
|
| 23500545 |
de Weille J et al.:
Oxysterols in cancer cell proliferation and death
Biochem. Pharmacol.
2013
86: 154-160
|
| 21239045 |
Feng Z et al.:
Mammalian target of rapamycin regulates expression of beta-catenin in hepatocellular carcinoma
Hum. Pathol.
2011
42: 659-668
|
| 23657817 |
Boscher C et al.:
Galectin-3- and phospho-caveolin-1-dependent outside-in integrin signaling mediates the EGF motogenic response in mammary cancer cells
Mol. Biol. Cell
2013
24: 2134-2145
|
| 21719054 |
Taylor CJ et al.:
Integrin-linked kinase regulates phosphatase and tensin homologue activity to promote tumorigenesis in neuroblastoma cells
Surgery
2011
150: 162-168
|
| 23796563 |
Antico Arciuch VG et al.:
Inhibition of AMPK and Krebs cycle gene expression drives metabolic remodeling of Pten-deficient preneoplastic thyroid cells
Cancer Res.
2013
73: 5459-5472
|
| 18339839 |
McDonald PC et al.:
Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival
Cancer Res.
2008
68: 1618-1624
|
| 24072782 |
Lamming DW et al.:
Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2)
FASEB J.
2014
28: 300-315
|
| 11719506 |
Yoon JW et al.:
Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation
J. Biol. Chem.
2002
277: 5548-5555
|
| 19706761 |
Lo HW et al.:
A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion
Cancer Res.
2009
69: 6790-6798
|
| 15737636 |
Hu H et al.:
Alpha-actinin-2, a cytoskeletal protein, binds to angiogenin
Biochem. Biophys. Res. Commun.
2005
329: 661-667
|
| 24947164 |
Bavarva JH et al.:
Nicotine and oxidative stress induced exomic variations are concordant and overrepresented in cancer-associated genes
Oncotarget
2014
5: 4788-4798
|
| 25281745 |
Cole SP et al.:
Multidrug resistance protein 1 (MRP1, ABCC1), a multitasking ATP-binding cassette (ABC) transporter
J. Biol. Chem.
2014
289
|
| 26180030 |
Ho CH et al.:
Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway
|
| 24345474 |
author information missing
Integrative DNA methylation and gene expression analysis in high-grade soft tissue sarcomas
Genome Biol.
2013
14: R137
|
| 25367630 |
Kiehl S et al.:
ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth
Sci Rep
2014
4: 6899
|
| 23147569 |
Kurundkar D et al.:
Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model
Toxicol. Appl. Pharmacol.
2013
266: 233-244
|
| 25060902 |
Kowshik J et al.:
Ellagic acid inhibits VEGF/VEGFR2, PI3K/Akt and MAPK signaling cascades in the hamster cheek pouch carcinogenesis model
Anticancer Agents Med Chem
2014
14: 1249-1260
|
| 23965899 |
Dai W et al.:
Promoter CpG island methylation of genes in key cancer pathways associates with clinical outcome in high-grade serous ovarian cancer
Clin. Cancer Res.
2013
19: 5788-5797
|
| 14578676 |
Kraus LA et al.:
The mechanism of action of docetaxel (Taxotere) in xenograft models is not limited to bcl-2 phosphorylation
Invest New Drugs
2003
21: 259-268
|
| 23608536 |
Aschauer L et al.:
Delineation of the key aspects in the regulation of epithelial monolayer formation
Mol. Cell. Biol.
2013
33: 2535-2550
|
| 25945730 |
Mariani A et al.:
Differential Targeting of Human Topoisomerase II Isoforms with Small Molecules
J. Med. Chem.
2015
58: 4851-4856
|
| 24186357 |
de Souza WF et al.:
Ouabain-induced alterations of the apical junctional complex involve alpha1 and beta1 Na,K-ATPase downregulation and ERK1/2 activation independent of caveolae in colorectal cancer cells
J. Membr. Biol.
2014
247: 23-33
|
| 20610891 |
Yamaguchi H et al.:
Transport of estrone 3-sulfate mediated by organic anion transporter OATP4C1: estrone 3-sulfate binds to the different recognition site for digoxin in OATP4C1
Drug Metab. Pharmacokinet.
2010
25: 314-317
|
| 14993604 |
Mikkaichi T et al.:
Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney
Proc. Natl. Acad. Sci. U.S.A.
2004
101: 3569-3574
|
| 15050519 |
Geyer J et al.:
Molecular cloning and functional characterization of the bovine (Bos taurus) organic anion transporting polypeptide Oatp1a2 (Slco1a2)
Comp. Biochem. Physiol. B
2004
137: 317-329
|
| 12351693 |
Pizzagalli F et al.:
Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter
Mol. Endocrinol.
2002
16: 2283-2296
|
| 19775282 |
Tammam J et al.:
Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia
Br. J. Pharmacol.
2009
158: 1183-1195
|
| 20332460 |
Okuhashi Y et al.:
Effects of gamma-secretase inhibitors on the growth of leukemia cells
Anticancer Res.
2010
30: 495-498
|
| 15448035 |
Dutcher JP et al.:
Mammalian target of rapamycin inhibition
Clin. Cancer Res.
2004
10: 6382
|
| 21652061 |
Kiewisz J et al.:
Gene expression of WNTs, beta-catenin and E-cadherin during the periimplantation period of pregnancy in pigs--involvement of steroid hormones
Theriogenology
2011
76: 687-699
|
| 18000824 |
Peng D et al.:
Alterations in Barretts-related adenocarcinomas: a proteomic approach
Int. J. Cancer
2008
122: 1303-1310
|
| 24382387 |
author information missing
New and emerging HDAC inhibitors for cancer treatment
J. Clin. Invest.
2014
124: 30-39
|
| 25247487 |
Erdem M et al.:
herg1b expression as a potential specific marker in pediatric acute myeloid leukemia patients with HERG 897K/K genotype
Pediatr Hematol Oncol
2015
32: 182-192
|
| 25098424 |
Prada J et al.:
Significant decreases of interleukin-1alpha gene expression after application of the serotonin receptor antagonist ondansetron are found to correlate with antiproliferative properties in the acute lymphoblastic leukemia cell line REH
Leuk. Lymphoma
2015
56: 1157-1159
|
| 25674239 |
Quesada AE et al.:
Morphoproteomics identifies constitutive activation of the mTORC2/Akt and NF-kappaB pathways and expressions of IGF-1R, Sirt1, COX-2, and FASN in peripheral T-cell lymphomas: pathogenetic implications and therapeutic options
Int J Clin Exp Pathol
2014
7: 8732-8739
|
| 12431979 |
Crociani O et al.:
Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells
J. Biol. Chem.
2003
278: 2947-2955
|
| 24570000 |
Tanaka T et al.:
Neuroendocrine signaling via the serotonin transporter regulates clearance of apoptotic cells
J. Biol. Chem.
2014
289
|
| 9029730 |
Labrie F et al.:
The key role of 17 beta-hydroxysteroid dehydrogenases in sex steroid biology
Steroids
1997
62: 148-158
|
| 20435002 |
Juntti SA et al.:
The androgen receptor governs the execution, but not programming, of male sexual and territorial behaviors
Neuron
2010
66: 260-272
|
| 23591044 |
Chuffa LG et al.:
Melatonin and ethanol intake exert opposite effects on circulating estradiol and progesterone and differentially regulate sex steroid receptors in the ovaries, oviducts, and uteri of adult rats
Reprod. Toxicol.
2013
39: 40-49
|
| 22375794 |
Kirpich I et al.:
Binge alcohol-induced microvesicular liver steatosis and injury are associated with down-regulation of hepatic Hdac 1, 7, 9, 10, 11 and up-regulation of Hdac 3
Alcohol. Clin. Exp. Res.
2012
36: 1578-1586
|
| 7424707 |
et al.:
Acetaldehyde directly inhibits the conversion of androstenedione to testosterone in the testes
Adv. Exp. Med. Biol.
1980
132: 211-217
|
| 14534309 |
Ali MK et al.:
Elevated intracellular calcium triggers recruitment of the receptor cross-talk accessory protein calcyon to the plasma membrane
J. Biol. Chem.
2003
278
|
| 8631893 |
Edelman AM et al.:
Multiple Ca(2+)-calmodulin-dependent protein kinase kinases from rat brain. Purification, regulation by Ca(2+)-calmodulin, and partial amino acid sequence
J. Biol. Chem.
1996
271
|
| 22212478 |
Anastasiou D et al.:
Breathless cancer cells get fat on glutamine
Cell Res.
2012
3: 443-446
|
| 21540236 |
Ben Sahra I et al.:
Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1
Cancer Res.
2011
71: 4366-4372
|
| 11130979 |
Aledo JC et al.:
Identification of two human glutaminase loci and tissue-specific expression of the two related genes
Mamm. Genome
2000
11: 1107-1110
|
| 11015561 |
Elgadi KM et al.:
Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing
Physiol. Genomics
1999
1: 51-62
|
| 19428809 |
Szeliga M et al.:
Glutamine in neoplastic cells: focus on the expression and roles of glutaminases
Neurochem. Int.
2009
55: 71-75
|
| 22665485 |
Hyodo T et al.:
Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis
J. Biol. Chem.
2012
287
|
| 25250919 |
Wong M et al.:
Silencing of STRN4 suppresses the malignant characteristics of cancer cells
Cancer Sci.
2014
105: 1526-1532
|
| 15469942 |
Hu Y et al.:
Identification and functional characterization of a novel human misshapen/Nck interacting kinase-related kinase, hMINK beta
J. Biol. Chem.
2004
279
|
| 26240284 |
Li Y et al.:
Histone Deacetylase 10 Regulates the Cell Cycle G2/M Phase Transition via a Novel Let-7-HMGA2-Cyclin A2 Pathway
Mol. Cell. Biol.
2015
35: 3547-3565
|
| 22117616 |
Viollet B et al.:
Cellular and molecular mechanisms of metformin: an overview
Clin Sci (Lond)
2012
122: 253-270
|
| 20510874 |
Kitamoto S et al.:
Promoter hypomethylation contributes to the expression of MUC3A in cancer cells
Biochem. Biophys. Res. Commun.
2010
397: 333-339
|
| 17885581 |
Heimerl S et al.:
Mapping ATP-binding cassette transporter gene expression profiles in melanocytes and melanoma cells
Melanoma Res.
2007
17: 265-273
|
| 14973057 |
Yasui K et al.:
Alteration in copy numbers of genes as a mechanism for acquired drug resistance
Cancer Res.
2004
64: 1403-1410
|
| 19460998 |
Vander Heiden MG et al.:
Understanding the Warburg effect: the metabolic requirements of cell proliferation
Science
2009
5930: 1029-1033
|
| 25672512 |
Ngo DC et al.:
Introduction to the molecular basis of cancer metabolism and the Warburg effect
Mol. Biol. Rep.
2015
42: 819-823
|
| 23770033 |
Ishibashi Y et al.:
New insights on glucosylated lipids: metabolism and functions
Biochim. Biophys. Acta
2013
1831: 1475-1485
|
| 24482631 |
Cantoria MJ et al.:
Contextual inhibition of fatty acid synthesis by metformin involves glucose-derived acetyl-CoA and cholesterol in pancreatic tumor cells
Metabolomics
2014
10: 91-104
|
| 21496237 |
Alhosin M et al.:
Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties
J. Exp. Clin. Cancer Res.
2011
30: 41
|
| 21214517 |
Tien AL et al.:
UHRF1 depletion causes a G2/M arrest, activation of DNA damage response and apoptosis
Biochem. J.
2011
435: 175-185
|
| 22094461 |
Di Fulvio M et al.:
Phospholipase D2 (PLD2) shortens the time required for myeloid leukemic cell differentiation: mechanism of action
J. Biol. Chem.
2012
287: 393-407
|
| 12972546 |
Kogata N et al.:
Identification of Fer tyrosine kinase localized on microtubules as a platelet endothelial cell adhesion molecule-1 phosphorylating kinase in vascular endothelial cells
Mol. Biol. Cell
2003
9: 3553-3564
|
| 21159660 |
Zhang S et al.:
Fes tyrosine kinase expression in the tumor niche correlates with enhanced tumor growth, angiogenesis, circulating tumor cells, metastasis, and infiltrating macrophages
Cancer Res.
2011
71: 1465-1473
|
| 11994747 |
Greer P et al.:
Closing in on the biological functions of Fps/Fes and Fer
Nat. Rev. Mol. Cell Biol.
2002
3: 278-289
|
| 23327920 |
Heideman MR et al.:
Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function
Blood
2013
121: 2038-2050
|
| 22286234 |
Hwang IY et al.:
pVHL-mediated transcriptional repression of c-Myc by recruitment of histone deacetylases
Mol. Cells
2012
33: 195-201
|
| 27456357 |
Zhao Y et al.:
Knockdown of USP39 induces cell cycle arrest and apoptosis in melanoma
|
| 26549013 |
Du WQ et al.:
The diverse oncogenic and tumor suppressor roles of salt-inducible kinase (SIK) in cancer
Expert Opin. Ther. Targets
2016
20: 477-485
|
| 15280358 |
Zheng G et al.:
ZNF76, a novel transcriptional repressor targeting TATA-binding protein, is modulated by sumoylation
J. Biol. Chem.
2004
279
|
| 14993291 |
Frederick JP et al.:
Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element
Mol. Cell. Biol.
2004
24: 2546-2559
|
| 26927084 |
Mico V et al.:
Nutrigenetics and Nutrimiromics of the Circadian System: The Time for Human Health
Int J Mol Sci
2016
3: 299
|
| 16247010 |
Armanios M et al.:
Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
Proc. Natl. Acad. Sci. U.S.A.
2005
102
|
| 15339924 |
Radhika V et al.:
Galpha13 stimulates cell migration through cortactin-interacting protein Hax-1
J. Biol. Chem.
2004
279
|
| 26045258 |
author information missing
article information missing
|
| 19118533 |
author information missing
article information missing
|
| 28088877 |
Miro C et al.:
The Concerted Action of Type 2 and Type 3 Deiodinases Regulates the Cell Cycle and Survival of Basal Cell Carcinoma Cells
Thyroid
2017
27: 567-576
|
| 27940296 |
Poplawski P et al.:
Induction of type 1 iodothyronine deiodinase expression inhibits proliferation and migration of renal cancer cells
Mol Cell Endocrinol
2017
442: 58-67
|
| 19139564 |
Ding L et al.:
Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway
J. Clin. Invest.
2009
119: 349-361
|
| 19734940 |
et al.:
|
| 25408199 |
et al.:
|
| 26936520 |
author information missing
article information missing
|
| 27036023 |
Li X et al.:
Smurf1 regulation of DAB2IP controls cell proliferation and migration
Oncotarget
2016
7
|
| 19903888 |
Xie D et al.:
DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis
Proc. Natl. Acad. Sci. U.S.A.
2009
47
|
| 18802005 |
Kometani K et al.:
Essential role of Rap signal in pre-TCR-mediated beta-selection checkpoint in alphabeta T-cell development
Blood
2008
112: 4565-4573
|
| 24058639 |
Asano Y et al.:
Fli1 represses transcription of the human alpha2(I) collagen gene by recruitment of the HDAC1/p300 complex
PLoS ONE
2013
8
|
| 20109457 |
Fortier AM et al.:
Akt isoforms regulate intermediate filament protein levels in epithelial carcinoma cells
FEBS Lett.
2010
584: 984-988
|
| 15607964 |
Fei P et al.:
Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth
Cancer Cell
2004
6: 597-609
|
| 26061814 |
Rueda-Rincon N et al.:
p53 attenuates AKT signaling by modulating membrane phospholipid composition
Oncotarget
2015
6
|
| 17570005 |
Stachowska E et al.:
Conjugated linoleic acids can change phagocytosis of human monocytes/macrophages by reduction in Cox-2 expression
Lipids
2007
42: 707-716
|
| 23691101 |
Zeilinger S et al.:
Tobacco smoking leads to extensive genome-wide changes in DNA methylation
PLoS ONE
2013
8
|
| 22232023 |
Monick MM et al.:
Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2012
159B: 141-151
|
| 18156284 |
Koenig W et al.:
Prospective study of high-sensitivity C-reactive protein as a determinant of mortality: results from the MONICA/KORA Augsburg Cohort Study, 1984-1998
Clin. Chem.
2008
54: 335-342
|
| 26432781 |
Sun L et al.:
NHERF1 regulates actin cytoskeleton organization through modulation of alpha-actinin-4 stability
FASEB J.
2016
30: 578-589
|
| 24853887 |
Chilton FH et al.:
Diet-gene interactions and PUFA metabolism: a potential contributor to health disparities and human diseases
Nutrients
2014
6: 1993-2022
|
| 17337246 |
Ariel A et al.:
Resolvins and protectins in the termination program of acute inflammation
Trends Immunol.
2007
28: 176-183
|
| 25863084 |
Zhang Y et al.:
[Identification of proteins interacting with the circadian clock protein PER1 in tumors using bacterial two-hybrid system technique]
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
2015
32: 192-197
|
| 20847954 |
Kim JY et al.:
Activation of CD147 with cyclophilin a induces the expression of IFITM1 through ERK and PI3K in THP-1 cells
Mediators Inflamm.
2010
2010
|
| 15767684 |
Engels IH et al.:
Caspase-10 sensitizes breast carcinoma cells to TRAIL-induced but not tumor necrosis factor-induced apoptosis in a caspase-3-dependent manner
Mol. Cell. Biol.
2005
25: 2808-2818
|
| 15772077 |
Milhas D et al.:
Caspase-10 triggers Bid cleavage and caspase cascade activation in FasL-induced apoptosis
J. Biol. Chem.
2005
280
|
| 27008177 |
Gschweitl M et al.:
A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes
Elife
2016
5
|
| 22031019 |
Kari V et al.:
The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair
Cell Cycle
2011
10: 3495-3504
|
| 25978653 |
Liu Y et al.:
Silencing of Receptor Tyrosine Kinase ROR1 Inhibits Tumor-Cell Proliferation via PI3K/AKT/mTOR Signaling Pathway in Lung Adenocarcinoma
PLoS ONE
2015
10
|
| 22194605 |
Ma W et al.:
MicroRNA-29a inhibited epididymal epithelial cell proliferation by targeting nuclear autoantigenic sperm protein (NASP)
J. Biol. Chem.
2012
287
|
| 20167597 |
Osakabe A et al.:
Nucleosome formation activity of human somatic nuclear autoantigenic sperm protein (sNASP)
J. Biol. Chem.
2010
285
|
| 19553603 |
Alekseev OM et al.:
Linker histones stimulate HSPA2 ATPase activity through NASP binding and inhibit CDC2/Cyclin B1 complex formation during meiosis in the mouse
Biol. Reprod.
2009
81: 739-748
|
| 16080155 |
Alekseev OM et al.:
Mass spectrometry identification of NASP binding partners in HeLa cells
Proteins
2005
61: 1-5
|
| 21376665 |
Perl A et al.:
Oxidative stress, inflammation and carcinogenesis are controlled through the pentose phosphate pathway by transaldolase
Trends Mol Med
2011
17: 395-403
|
| 25015087 |
Jiang P et al.:
Regulation of the pentose phosphate pathway in cancer
Protein Cell
2014
5: 592-602
|
| 17606868 |
Yuneva M et al.:
Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells
J. Cell Biol.
2007
178: 93-105
|
| 25619394 |
Xiao WJ et al.:
Modulation of the pentose phosphate pathway alters phase I metabolism of testosterone and dextromethorphan in HepG2 cells
Acta Pharmacol. Sin.
2015
36: 259-267
|
| 22860010 |
Stanton PG et al.:
Proteomic changes in rat spermatogenesis in response to in vivo androgen manipulation; impact on meiotic cells
PLoS ONE
2012
7
|
| 16728391 |
Richardson RT et al.:
Nuclear autoantigenic sperm protein (NASP), a linker histone chaperone that is required for cell proliferation
J. Biol. Chem.
2006
281
|
| 26248089 |
Qiu Z et al.:
MicroRNA-124 reduces the pentose phosphate pathway and proliferation by targeting PRPS1 and RPIA mRNAs in human colorectal cancer cells
Gastroenterology
2015
149: 1587-1598
|
| 17145697 |
Fan TW et al.:
Integrating metabolomics and transcriptomics for probing SE anticancer mechanisms
Drug Metab. Rev.
2006
38: 707-732
|
| 28031192 |
Playdon MC et al.:
Identifying biomarkers of dietary patterns by using metabolomics
Am. J. Clin. Nutr.
2017
105: 450-465
|
| 29056512 |
Rios Garcia M et al.:
Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence
|
| 28380384 |
Krishnaiah SY et al.:
Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism
Cell Metab.
2017
25: 961-974.e4
|
| 20530237 |
Fang W et al.:
Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein
Carcinogenesis
2010
31: 1360-1366
|
| 27221515 |
Gibbons H et al.:
Metabolomics as a tool in the identification of dietary biomarkers
Proc Nutr Soc
2017
76: 42-53
|
| 18061431 |
Waldecker M et al.:
Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon
J. Nutr. Biochem.
2008
19: 587-593
|
| 27224877 |
Lamuel-Raventos RM et al.:
Prebiotic nut compounds and human microbiota
Crit Rev Food Sci Nutr
2017
57: 3154-3163
|
| 28178522 |
Brown MC et al.:
MNK Controls mTORC1:Substrate Association through Regulation of TELO2 Binding with mTORC1
Cell Rep
2017
18: 1444-1457
|
| 25243985 |
Stincone A et al.:
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
Biol Rev Camb Philos Soc
2015
90: 927-963
|
| 29343522 |
Schwab A et al.:
Polyol pathway links glucose metabolism to the aggressiveness of cancer cells
|
| 18815282 |
Jiao Y et al.:
Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator
Blood
2009
113: 462-469
|
| 28074653 |
Nelson KM et al.:
The Essential Medicinal Chemistry of Curcumin
J. Med. Chem.
2017
60: 1620-1637
|
| 28287627 |
Bi X et al.:
Plasma-free amino acid profiles are predictors of cancer and diabetes development
Nutr Diabetes
2017
7: e249
|
| 27098510 |
Aughey GN et al.:
Metabolic regulation via enzyme filamentation
Crit. Rev. Biochem. Mol. Biol.
2015
51: 282-293
|
| 22180458 |
Baresova V et al.:
Mutations of ATIC and ADSL affect purinosome assembly in cultured skin fibroblasts from patients with AICA-ribosiduria and ADSL deficiency
Hum. Mol. Genet.
2012
21: 1534-1543
|
| 24289548 |
Verit FF et al.:
Endometriosis, leiomyoma and adenomyosis: the risk of gynecologic malignancy
Asian Pac. J. Cancer Prev.
2013
14: 5589-5597
|
| 29720963 |
Buj R et al.:
Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease
Front Endocrinol (Lausanne)
2018
9: 177
|
| 24474794 |
Liu X et al. et al.:
Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK
Proc. Natl. Acad. Sci. U.S.A.
2014
111: E435-E444
|
| 28401189 |
Timofeev O et al.:
p53 gain-of-function mutations promote metastasis via ENTPD5 upregulation and enhanced N-glycoprotein folding
Mol Cell Oncol
2017
4
|
| 25794010 |
Xue Y et al.:
ENTPD5 induces apoptosis in lung cancer cells via regulating caspase 3 expression
PLoS ONE
2015
10
|
| 21074248 |
Fang M et al.:
The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway
Cell
2010
143: 711-724
|
| 21519793 |
Tada Y et al.:
Ectonucleoside triphosphate diphosphohydrolase 6 expression in testis and testicular cancer and its implication in cisplatin resistance
Oncol. Rep.
2011
26: 161-167
|
| 23941513 |
Yan X et al. et al.:
The identification of novel targets of miR-16 and characterization of their biological functions in cancer cells
Mol. Cancer
2013
12: 92
|
| 19214193 |
Cooper EM et al.:
K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1
EMBO J.
2009
28: 621-631
|
| 20032457 |
Cooper EM et al.:
Specificity of the BRISC deubiquitinating enzyme is not due to selective binding to Lys63-linked polyubiquitin
J. Biol. Chem.
2010
285
|
| 26928556 |
Chen Y et al.:
WAP four-disulfide core domain protein 2 gene(WFDC2) is a target of estrogen in ovarian cancer cells
J Ovarian Res
2016
9: 10
|
| 28442573 |
Cheng X et al. et al.:
Cell cycle-dependent degradation of the methyltransferase SETD3 attenuates cell proliferation and liver tumorigenesis
J. Biol. Chem.
2017
292: 9022-9033
|
| 17160626 |
Gu X et al.:
Cloning and characterization of a gene encoding the human putative ubiquitin conjugating enzyme E2Z (UBE2Z)
Mol. Biol. Rep.
2007
34: 183-188
|
| 27292798 |
Abdul Rehman SA et al.:
MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes
Mol. Cell
2016
63: 146-155
|
| 25183871 |
Kizil C et al.:
Simplet/Fam53b is required for Wnt signal transduction by regulating beta-catenin nuclear localization
Development
2014
141: 3529-3539
|
| 16611694 |
Thermes V et al.:
Medaka simplet (FAM53B) belongs to a family of novel vertebrate genes controlling cell proliferation
Development
2006
133: 1881-1890
|
| 20656690 |
Feng L et al.:
The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments
J. Biol. Chem.
2010
285
|
| 24075985 |
Zheng H et al.:
A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses
Cell Rep
2013
5: 180-193
|
| 30542727 |
Piao L et al.:
Histone methyltransferase SUV39H2 serves oncogenic roles in osteosarcoma
Oncol Rep
2019
41: 325-332
|
| 27568929 |
Wong SJ et al.:
KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1
Structure
2016
24: 1795-1801
|
| 27325824 |
Her J et al.:
Factors forming the BRCA1-A complex orchestrate BRCA1 recruitment to the sites of DNA damage
Acta Biochim. Biophys. Sin. (Shanghai)
2016
48: 658-664
|
| 20300062 |
Benard G et al.:
IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation
EMBO J.
2010
29: 1458-1471
|
| 28943312 |
Michel MA et al.:
Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
Mol. Cell
2017
68: 233-246.e5
|
| 29892060 |
Janic A et al. et al.:
DNA repair processes are critical mediators of p53-dependent tumor suppression
Nat. Med.
2018
24: 947-953
|
| 26187670 |
Ju UI et al.:
FBXO11 represses cellular response to hypoxia by destabilizing hypoxia-inducible factor-1alpha mRNA
Biochem. Biophys. Res. Commun.
2015
464: 1008-1015
|
| 23431138 |
Chiorazzi M et al. et al.:
Related F-box proteins control cell death in Caenorhabditis elegans and human lymphoma
Proc. Natl. Acad. Sci. U.S.A.
2013
110: 3943-3948
|
| 16427630 |
Huang J et al.:
The p53-inducible E3 ubiquitin ligase p53RFP induces p53-dependent apoptosis
FEBS Lett.
2006
580: 940-947
|
| 17080297 |
Li Q et al.:
Introduction of G1 phase arrest in Human Hepatocellular carcinoma cells (HHCC) by APMCF1 gene transfection through the down-regulation of TIMP3 and up-regulation of the CDK inhibitors p21
Mol. Biol. Rep.
2006
33: 257-263
|
| 19664239 |
Zhang Y et al.:
Subcellular localization of APMCF1 and its biological significance of expression pattern in normal and malignant human tissues
J. Exp. Clin. Cancer Res.
2009
28: 111
|
| 18344599 |
Abe K et al.:
Pirh2 interacts with and ubiquitylates signal recognition particle receptor beta subunit
Biomed. Res.
2008
29: 53-60
|
| 20940296 |
Duan L et al. et al.:
Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration
J. Biol. Chem.
2011
286: 620-633
|
| 22659877 |
Guil S et al.:
Intronic RNAs mediate EZH2 regulation of epigenetic targets
Nat Struct Mol Biol
2012
19: 664-670
|
| 27743347 |
Zeng S et al.:
E3 ligase UHRF2 stabilizes the acetyltransferase TIP60 and regulates H3K9ac and H3K14ac via RING finger domain
Protein Cell
2017
8: 202-218
|
| 22673569 |
Mori T et al.:
NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscape
FEBS Lett.
2012
586: 1570-1583
|
| 27692986 |
Lin M et al.:
USP38 Inhibits Type I Interferon Signaling by Editing TBK1 Ubiquitination through NLRP4 Signalosome
Mol. Cell
2016
64: 267-281
|
| 30497519 |
Liu W et al.:
The deubiquitinase USP38 affects cellular functions through interacting with LSD1
Biol. Res.
2018
51: 53
|
| 26416890 |
Daou S et al. et al.:
The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer
J. Biol. Chem.
2015
290
|
| 28031328 |
An H et al. et al.:
Interactome Analysis Reveals a Novel Role for RAD6 in the Regulation of Proteasome Activity and Localization in Response to DNA Damage
|
| 21502320 |
Balasubramanian S et al.:
The interferon-gamma-induced GTPase, mGBP-2, inhibits tumor necrosis factor alpha (TNF-alpha) induction of matrix metalloproteinase-9 (MMP-9) by inhibiting NF-kappaB and Rac protein
J. Biol. Chem.
2011
286
|
| 30881114 |
Tong H et al.:
INTS8 accelerates the epithelial-to-mesenchymal transition in hepatocellular carcinoma by upregulating the TGF-beta signaling pathway
Cancer Manag Res
2019
11: 1869-1879
|
| 29663841 |
Piek A et al.:
Novel heart failure biomarkers: why do we fail to exploit their potential?
Crit Rev Clin Lab Sci
2018
55: 246-263
|
| 18712719 |
Naro Y et al.:
Aryl amide small-molecule inhibitors of microRNA miR-21 function
Bioorg. Med. Chem. Lett.
2015
25: 4793-4796
|
| 26220158 |
Naro Y et al.:
Aryl amide small-molecule inhibitors of microRNA miR-21 function
Bioorg. Med. Chem. Lett.
2015
25: 4793-4796
|
| 30962205 |
Sperling SA et al. et al.:
Chronic CD30-signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells
|
| 29910466 |
Sun J et al.:
XK-related protein 5 (XKR5) is a novel negative regulator of KIT/D816V-mediated transformation
Oncogenesis
2018
7: 48
|
| 27114453 |
Lai M et al.:
Multidimensional Proteomics Reveals a Role of UHRF2 in the Regulation of Epithelial-Mesenchymal Transition (EMT)
Mol. Cell Proteomics
2016
15: 2263-2278
|
| 28004105 |
Zhang T et al.:
UHRF2 decreases H3K9ac expression by interacting with it through the PHD and SRA/YDG domain in HepG2 hepatocellular carcinoma cells
Int. J. Mol. Med.
2017
39: 126-134
|
| 23404503 |
Oh Y et al.:
UHRF2, a ubiquitin E3 ligase, acts as a small ubiquitin-like modifier E3 ligase for zinc finger protein 131
J. Biol. Chem.
2013
288: 9102-9111
|
| 18698484 |
Katoh Y et al.:
Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review)
Int. J. Mol. Med.
2008
22: 271-275
|
| 12579345 |
Katoh M et al.:
Identification and characterization of human SNAIL3 (SNAI3) gene in silico
Int. J. Mol. Med.
2003
11: 383-388
|
| 16959903 |
Yu YX et al.:
Syntaxin 1A promotes the endocytic sorting of EAAC1 leading to inhibition of glutamate transport
J. Cell. Sci.
2006
119: 3776-3787
|
| 29163677 |
Tao Y et al.:
TRIM37 promotes tumor cell proliferation and drug resistance in pediatric osteosarcoma
Oncol Lett
2017
14: 6365-6372
|
| 31024001 |
Sanchez-Fernandez C et al.:
UHRF genes regulate programmed interdigital tissue regression and chondrogenesis in the embryonic limb
Cell Death Dis
2019
10: 347
|
| 28900727 |
Chen XR et al.:
Uhrf2 deletion impairs the formation of hippocampus-dependent memory by changing the structure of the dentate gyrus
Brain Struct Funct
2018
223: 609-618
|
| 28402695 |
Liu Y et al.:
UHRF2 regulates local 5-methylcytosine and suppresses spontaneous seizures
Epigenetics
2017
12: 551-560
|
| 29270024 |
Peng R et al.:
Overexpression of UHRF2 in intrahepatic cholangiocarcinoma and its clinical significance
Onco Targets Ther
2017
10: 5863-5872
|
| 23244124 |
Wu TF et al.:
UHRF2 mRNA expression is low in malignant glioma but silencing inhibits the growth of U251 glioma cells in vitro
Asian Pac. J. Cancer Prev.
2012
13: 5137-5142
|
| 27738314 |
Lu H et al.:
Loss of UHRF2 expression is associated with human neoplasia, promoter hypermethylation, decreased 5-hydroxymethylcytosine, and high proliferative activity
Oncotarget
2016
7
|
| 24573556 |
Lu S et al.:
Ubiquitin-like with PHD and ring finger domains 2 is a predictor of survival and a potential therapeutic target in colon cancer
Oncol. Rep.
2014
31: 1802-1810
|
| 23598597 |
Grondahl ML et al.:
The dormant and the fully competent oocyte: comparing the transcriptome of human oocytes from primordial follicles and in metaphase II
Mol. Hum. Reprod.
2013
19: 600-617
|
| 29923055 |
Wang Y et al.:
UHRF2 promotes DNA damage response by decreasing p21 via RING finger domain
Biotechnol. Lett.
2018
40: 1181-1188
|
| 23833190 |
Lu H et al.:
The nuclear protein UHRF2 is a direct target of the transcription factor E2F1 in the induction of apoptosis
J. Biol. Chem.
2013
288
|
| 12176013 |
Mori T et al.:
NIRF, a novel RING finger protein, is involved in cell-cycle regulation
Biochem. Biophys. Res. Commun.
2002
296: 530-536
|
| 29162697 |
Bouguenina H et al.:
EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions
Proc. Natl. Acad. Sci. U.S.A.
2017
114
|
| 30030436 |
Snuderl M et al. et al.:
Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma
Nat Commun
2018
9: 2868
|
| 12175857 |
Quick MW et al.:
Role of syntaxin 1A on serotonin transporter expression in developing thalamocortical neurons
Int. J. Dev. Neurosci.
2002
20: 219-224
|
| 25531179 |
Graves CA et al.:
Neuroendocrine Merkel cell carcinoma is associated with mutations in key DNA repair, epigenetic and apoptosis pathways: a case-based study using targeted massively parallel sequencing
Neuroendocrinology
2015
101: 112-119
|
| 28389907 |
Chang YC et al. et al.:
Targeted next-generation sequencing identified novel mutations in triple-negative myeloproliferative neoplasms
Med. Oncol.
2017
34: 83
|
| 24889606 |
Harkcom WT et al.:
NAD+ and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents
Proc. Natl. Acad. Sci. U.S.A.
2014
111
|
| 30881024 |
Yan Y et al.:
RRAD suppresses the Warburg effect by downregulating ACTG1 in hepatocellular carcinoma
Onco Targets Ther
2019
12: 1691-1703
|
| 17195088 |
Suzuki M et al.:
Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers
Ann. Surg. Oncol.
2007
14: 1397-1404
|
| 21221513 |
Hsiao BY et al.:
Rad is a p53 direct transcriptional target that inhibits cell migration and is frequently silenced in lung carcinoma cells
J. Mol. Med.
2011
89: 481-492
|
| 24648519 |
Wang Y et al. et al.:
Ras-induced epigenetic inactivation of the RRAD (Ras-related associated with diabetes) gene promotes glucose uptake in a human ovarian cancer model
J. Biol. Chem.
2014
289
|
| 29571613 |
Gigante ED et al.:
Hypomorphic Smo mutant with inefficient ciliary enrichment disrupts the highest level of vertebrate Hedgehog response
Dev. Biol.
2018
437: 152-162
|
| 30463017 |
Updegraff BL et al. et al.:
Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism
Cell Rep
2018
25: 2223-2233.e6
|
| 29069646 |
Rui YN et al.:
The Intracranial Aneurysm Gene THSD1 Connects Endosome Dynamics to Nascent Focal Adhesion Assembly
Cell. Physiol. Biochem.
2017
43: 2200-2211
|
| 28636940 |
Li Z et al.:
HECTD3 Mediates an HSP90-Dependent Degradation Pathway for Protein Kinase Clients
Cell Rep
2017
19: 2515-2528
|
| 30259712 |
Manyes L et al.:
Spatial learning and long-term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice
Brain Behav
2018
8
|
| 26900962 |
Lim SM et al.:
Alteration of Pituitary Tumor Transforming Gene-1 Regulates Trophoblast Invasion via the Integrin/Rho-Family Signaling Pathway
PLoS ONE
2016
11
|
| 30414538 |
Chteinberg E et al.:
Neuroendocrine Key Regulator Gene Expression in Merkel Cell Carcinoma
Neoplasia
2018
20: 1227-1235
|
| 30026867 |
Song J et al.:
Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/beta-catenin pathway in hepatocellular carcinoma
Theranostics
2018
8: 3571-3583
|
| 29906744 |
Ma W et al.:
MicroRNA-302c represses epithelial-mesenchymal transition and metastasis by targeting transcription factor AP-4 in colorectal cancer
Biomed. Pharmacother.
2018
105: 670-676
|
| 24500709 |
D'Annibale S et al.:
Proteasome-dependent degradation of transcription factor activating enhancer-binding protein 4 (TFAP4) controls mitotic division
J. Biol. Chem.
2014
289: 7730-7737
|
| 24885929 |
Dupasquier S et al.:
Validation of housekeeping gene and impact on normalized gene expression in clear cell renal cell carcinoma: critical reassessment of YBX3/ZONAB/CSDA expression
BMC Mol. Biol.
2014
15: 9
|
| 31189097 |
Cooke A et al.:
The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance
Cell Rep
2019
27: 3097-3106.e5
|
| 28500257 |
Jahn A et al.:
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator
EMBO Rep.
2017
18: 929-946
|
| 28082411 |
Li JS et al.:
TZAP: A telomere-associated protein involved in telomere length control
Science
2017
355: 638-641
|
| 28775165 |
Chen X et al.:
EZH2 Palmitoylation Mediated by ZDHHC5 in p53-Mutant Glioma Drives Malignant Development and Progression
Cancer Res.
2017
77: 4998-5010
|
| 22081607 |
Li Y et al.:
DHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells
J. Biol. Chem.
2012
287: 523-530
|
| 20178993 |
Li Y et al.:
DHHC5 interacts with PDZ domain 3 of post-synaptic density-95 (PSD-95) protein and plays a role in learning and memory
J. Biol. Chem.
2010
285
|
| 24562000 |
Brigidi GS et al.:
Palmitoylation of delta-catenin by DHHC5 mediates activity-induced synapse plasticity
Nat. Neurosci.
2014
17: 522-532
|
| 21673190 |
Goodwin EC et al.:
BiP and multiple DNAJ molecular chaperones in the endoplasmic reticulum are required for efficient simian virus 40 infection
mBio
2011
2
|
| 19692168 |
Guey LT et al. et al.:
Genetic susceptibility to distinct bladder cancer subphenotypes
Eur. Urol.
2010
57: 283-292
|
| 25631089 |
Bagchi P et al.:
The endoplasmic reticulum membrane J protein C18 executes a distinct role in promoting simian virus 40 membrane penetration
J Virol
2015
89: 4058-4068
|
| 16551573 |
Montesano Gesualdi N et al.:
AROS-29 is involved in adaptive response to oxidative stress
Free Radic. Res.
2006
40: 467-476
|
| 25967551 |
Ortmann C et al.:
Sonic hedgehog processing and release are regulated by glypican heparan sulfate proteoglycans
J. Cell. Sci.
2015
128: 2374-2385
|
| 24638979 |
Zhou ZJ et al.:
HNRNPAB induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by transcriptionally activating SNAIL
Cancer Res.
2014
74: 2750-2762
|
| 31470122 |
Wenta T et al.:
Cellular substrates and pro-apoptotic function of the human HtrA4 protease
J Proteomics
2019
209
|
| 31036715 |
Kummari R et al.:
Discerning the mechanism of action of HtrA4: a serine protease implicated in the cell death pathway
Biochem. J.
2019
476: 1445-1463
|
| 22745772 |
Kalinichenko SV et al.:
Identification of Nedd4 E3 ubiquitin ligase as a binding partner and regulator of MAK-V protein kinase
PLoS ONE
2012
7
|
| 21568852 |
Kalinichenko SV et al.:
Interaction between MAK-V protein kinase and synaptopodin
Biochemistry Mosc.
2011
76: 196-201
|
| 25881306 |
Reed KR et al.:
Hunk/Mak-v is a negative regulator of intestinal cell proliferation
BMC Cancer
2015
15: 110
|
| 29721195 |
author information missing
article information missing
|
| 31477752 |
An HJ et al.:
Myoferlin silencing inhibits VEGFR2-mediated proliferation of metastatic clear cell renal cell carcinoma
Sci Rep
2019
9: 12656
|
| 10072760 |
Kim IF et al.:
Isolation and characterization of IPP, a novel human gene encoding an actin-binding, kelch-like protein
Gene
1999
228: 73-83
|
| 30997569 |
Hu W et al.:
NAV2 facilitates invasion of cutaneous melanoma cells by targeting SNAI2 through the GSK-3beta/beta-catenin pathway
Arch. Dermatol. Res.
2019
311: 399-410
|
| 25152373 |
Liu H et al.:
SET-mediated NDRG1 inhibition is involved in acquisition of epithelial-to-mesenchymal transition phenotype and cisplatin resistance in human lung cancer cell
Cell. Signal.
2014
26: 2710-2720
|
| 24265802 |
Zarrinpashneh E et al.:
Ablation of SGK1 impairs endothelial cell migration and tube formation leading to decreased neo-angiogenesis following myocardial infarction
PLoS ONE
2013
8
|
| 25623114 |
De Silva D et al.:
Transcriptome analysis of the hormone-sensing cells in mammary epithelial reveals dynamic changes in early pregnancy
BMC Dev. Biol.
2015
15: 7
|
| 31052365 |
Hunsaker M et al.:
Differential MicroRNA Expression of miR-21 and miR-155 within Oral Cancer Extracellular Vesicles in Response to Melatonin
|
| 28724215 |
Gu J et al.:
Melatonin inhibits proliferation and invasion via repression of miRNA-155 in glioma cells
Biomed. Pharmacother.
2017
93: 969-975
|
| 23758864 |
Zhou W et al. et al.:
Over-expression of BCAT1, a c-Myc target gene, induces cell proliferation, migration and invasion in nasopharyngeal carcinoma
Mol. Cancer
2013
12: 53
|
| 12881716 |
Modena P et al.:
UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines
Oncogene
2003
22: 4586-4593
|
| 28332314 |
Park ER et al. et al.:
The mitochondrial hinge protein, UQCRH, is a novel prognostic factor for hepatocellular carcinoma
Cancer Med
2017
6: 749-760
|
| 29570613 |
Nie C et al.:
Branched Chain Amino Acids: Beyond Nutrition Metabolism
|
| 23973461 |
Sheren JE et al.:
RNF38 encodes a nuclear ubiquitin protein ligase that modifies p53
Biochem. Biophys. Res. Commun.
2013
440: 473-478
|
| 12074600 |
Eisenberg I et al.:
Cloning and characterization of a novel human gene RNF38 encoding a conserved putative protein with a RING finger domain
Biochem. Biophys. Res. Commun.
2002
294: 1169-1176
|
| 17634619 |
MacDonald TJ et al.:
Progression-associated genes in astrocytoma identified by novel microarray gene expression data reanalysis
Methods Mol. Biol.
2007
377: 203-222
|
| 31281549 |
Huang T et al.:
TFAP4 Promotes Hepatocellular Carcinoma Invasion and Metastasis via Activating the PI3K/AKT Signaling Pathway
Dis. Markers
2019
2019
|
| 23846687 |
Murakami Y et al.:
N-myc downstream-regulated gene 1 promotes tumor inflammatory angiogenesis through JNK activation and autocrine loop of interleukin-1alpha by human gastric cancer cells
J. Biol. Chem.
2013
288
|
| 26609485 |
Ellinger J et al.:
The long non-coding RNA lnc-ZNF180-2 is a prognostic biomarker in patients with clear cell renal cell carcinoma
Am J Cancer Res
2015
5: 2799-2807
|
| 31375012 |
Sobierajska K et al.:
TUBB4B Downregulation Is Critical for Increasing Migration of Metastatic Colon Cancer Cells
|
| 27239701 |
van Kuilenburg AB et al.:
The pivotal role of uridine-cytidine kinases in pyrimidine metabolism and activation of cytotoxic nucleoside analogues in neuroblastoma
Biochim. Biophys. Acta
2016
1862: 1504-1512
|
| 15156151 |
Marone R et al.:
Memo mediates ErbB2-driven cell motility
Nat. Cell Biol.
2004
6: 515-522
|
| 28115522 |
Chen R et al. et al.:
The 5-Hydroxymethylcytosine (5hmC) Reader UHRF2 Is Required for Normal Levels of 5hmC in Mouse Adult Brain and Spatial Learning and Memory
J. Biol. Chem.
2017
292: 4533-4543
|
| 22068036 |
Wang C et al.:
EZH2 Mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, RUNX3, and NGFR
Cancer Res.
2012
72: 315-324
|
| 29055779 |
Karg E et al.:
Ubiquitome Analysis Reveals PCNA-Associated Factor 15 (PAF15) as a Specific Ubiquitination Target of UHRF1 in Embryonic Stem Cells
J. Mol. Biol.
2017
429: 3814-3824
|
| 27129234 |
Liu Y et al.:
Zinc Finger Protein 618 Regulates the Function of UHRF2 (Ubiquitin-like with PHD and Ring Finger Domains 2) as a Specific 5-Hydroxymethylcytosine Reader
J. Biol. Chem.
2016
291
|
| 29490948 |
Ye S et al. et al.:
YAP1-Mediated Suppression of USP31 Enhances NFkappaB Activity to Promote Sarcomagenesis
Cancer Res.
2018
78: 2705-2720
|
| 16214042 |
Tzimas C et al.:
Human ubiquitin specific protease 31 is a deubiquitinating enzyme implicated in activation of nuclear factor-kappaB
Cell. Signal.
2006
18: 83-92
|
| 31138678 |
Figeac N et al. et al.:
VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle
|
| 31059752 |
Han Q et al. et al.:
Vps4A mediates the localization and exosome release of beta-catenin to inhibit epithelial-mesenchymal transition in hepatocellular carcinoma
Cancer Lett.
2019
457: 47-59
|
| 28316371 |
Schroeder L et al.:
ZNF395 Is an Activator of a Subset of IFN-Stimulated Genes
Mediators Inflamm.
2017
2017
|
| 24086395 |
Jordanovski D et al.:
The hypoxia-inducible transcription factor ZNF395 is controlled by IkB kinase-signaling and activates genes involved in the innate immune response and cancer
PLoS ONE
2013
8
|
| 24060497 |
Colombo J et al.:
Expression, purification and molecular analysis of the human ZNF706 protein
Biol Proced Online
2013
15: 10
|
| 21533872 |
Hu Y et al.:
RGS22, a novel cancer/testis antigen, inhibits epithelial cell invasion and metastasis
Clin. Exp. Metastasis
2011
28: 541-549
|
| 24403052 |
Stacey SN et al. et al.:
Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma
Hum. Mol. Genet.
2014
23: 3045-3053
|
| 22291991 |
Kajiho H et al.:
RINL, guanine nucleotide exchange factor Rab5-subfamily, is involved in the EphA8-degradation pathway with odin
PLoS ONE
2012
7
|
| 21419809 |
Woller B et al.:
Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22
Biochim. Biophys. Acta
2011
1813: 1198-1210
|
| 28493459 |
Yuan F et al.:
Enhanced NOLC1 promotes cell senescence and represses hepatocellular carcinoma cell proliferation by disturbing the organization of nucleolus
Aging Cell
2017
16: 726-737
|
| 29017577 |
Zhou PJ et al.:
Elevated expression of Par3 promotes prostate cancer metastasis by forming a Par3/aPKC/KIBRA complex and inactivating the hippo pathway
J. Exp. Clin. Cancer Res.
2017
36: 139
|
| 27039262 |
Prasad A et al. et al.:
Identification of Gene Mutations and Fusion Genes in Patients with Sezary Syndrome
J. Invest. Dermatol.
2016
136: 1490-1499
|
| 23626839 |
Ward CS et al.:
HDAC inhibition induces increased choline uptake and elevated phosphocholine levels in MCF7 breast cancer cells
PLoS ONE
2013
8
|
| 24532461 |
Inazu M et al.:
Choline transporter-like proteins CTLs/SLC44 family as a novel molecular target for cancer therapy
Biopharm Drug Dispos
2014
35: 431-449
|
| 11408570 |
Taylor EM et al.:
Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex
Mol. Biol. Cell
2001
12: 1583-1594
|
| 30476445 |
Aragon L et al.:
The Smc5/6 Complex: New and Old Functions of the Enigmatic Long-Distance Relative
Annu. Rev. Genet.
2018
52: 89-107
|
| 30120715 |
Chang YS et al.:
Detection of Molecular Alterations in Taiwanese Patients with Medullary Thyroid Cancer Using Whole-Exome Sequencing
Endocr. Pathol.
2018
29: 324-331
|
| 31541092 |
Garikipati VNS et al. et al.:
Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis
Nat Commun
2019
10: 4317
|
| 30988707 |
Bian T et al.:
Overexpression of fibronectin type III domain containing 3B is correlated with epithelial-mesenchymal transition and predicts poor prognosis in lung adenocarcinoma
Exp Ther Med
2019
17: 3317-3326
|
| 31570756 |
Guo F et al. et al.:
Recent BCR stimulation induces a negative autoregulatory loop via FBXO10 mediated degradation of HGAL
Leukemia
2020
34: 553-566
|
| 30129678 |
Toeda Y et al.:
FBLIM1 enhances oral cancer malignancy via modulation of the epidermal growth factor receptor pathway
Mol. Carcinog.
2018
57: 1690-1697
|
| 28902358 |
Ma Q et al.:
SERP1 is a novel marker of poor prognosis in pancreatic ductal adenocarcinoma patients via anti-apoptosis and regulating SRPRB/NF-kappaB axis
Int. J. Oncol.
2017
51: 1104-1114
|
| 26272184 |
Wang C et al.:
Suppression of motor protein KIF3C expression inhibits tumor growth and metastasis in breast cancer by inhibiting TGF-beta signaling
Cancer Lett.
2015
368: 105-114
|
| 23843507 |
Gumy LF et al.:
The kinesin-2 family member KIF3C regulates microtubule dynamics and is required for axon growth and regeneration
J. Neurosci.
2013
33
|
| 19223533 |
Cheng H et al.:
Hepatocyte growth factor activator inhibitor type 1 regulates epithelial to mesenchymal transition through membrane-bound serine proteinases
Cancer Res.
2009
69: 1828-1835
|
| 22116401 |
Hosoya N et al.:
Synaptonemal complex protein SYCP3 impairs mitotic recombination by interfering with BRCA2
EMBO Rep.
2011
13: 44-51
|
| 24498351 |
Miller GS et al.:
HATL5: a cell surface serine protease differentially expressed in epithelial cancers
PLoS ONE
2014
9
|
| 31911859 |
Xiao Z et al. et al.:
USP37 is a SNAI1 deubiquitinase
Am J Cancer Res
2019
9: 2749-2759
|
| 28320150 |
Wang N et al.:
Additional evidence supports association of common genetic variants in VTI1A and ETFA with increased risk of glioma susceptibility
J. Neurol. Sci.
2017
375: 282-288
|
| 27566589 |
Grandi A et al. et al.:
ERMP1, a novel potential oncogene involved in UPR and oxidative stress defense, is highly expressed in human cancer
Oncotarget
2016
7
|
| 30737284 |
Eisa NH et al. et al.:
The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis
J. Biol. Chem.
2019
294: 5246-5260
|
| 26740741 |
Arora A et al.:
Interplay Between Metabolism and Oncogenic Process: Role of microRNAs
Transl Oncogenomics
2015
7: 11-27
|
| 31921661 |
Pedroza-Torres A et al.:
MicroRNAs in Tumor Cell Metabolism: Roles and Therapeutic Opportunities
Front Oncol
2019
9: 1404
|
| 23827681 |
Mevissen TE et al. et al.:
OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis
Cell
2013
154: 169-184
|
| 31149030 |
Lin CZ et al.:
Chromosome 15q13 microduplication in a fetus with cardiac rhabdomyoma: a case report
Mol Cytogenet
2019
12: 24
|
| 23792447 |
Xu Z et al.:
Snail1-dependent transcriptional repression of Cezanne2 in hepatocellular carcinoma
Oncogene
2014
33: 2836-2845
|
| 29843216 |
Wang Q et al.:
Transcription factor KLF13 inhibits AKT activation and suppresses the growth of prostate carcinoma cells
Cancer Biomark
2018
22: 533-541
|
| 31323761 |
Fan X et al.:
14-3-3 Proteins Are on the Crossroads of Cancer, Aging, and Age-Related Neurodegenerative Disease
|
| 23913826 |
Wu L et al.:
ERG is a critical regulator of Wnt/LEF1 signaling in prostate cancer
Cancer Res.
2013
73: 6068-6079
|
| 30790560 |
Aoyama T et al.:
Identification of Coiled-Coil Domain-Containing Protein 180 and Leucine-Rich Repeat-Containing Protein 4 as Potential Immunohistochemical Markers for Liposarcoma Based on Proteomic Analysis Using Formalin-Fixed, Paraffin-Embedded Tissue
Am. J. Pathol.
2019
189: 1015-1028
|
| 24310606 |
Xiong L et al.:
NT5E and FcGBP as key regulators of TGF-1-induced epithelial-mesenchymal transition (EMT) are associated with tumor progression and survival of patients with gallbladder cancer
Cell Tissue Res.
2014
355: 365-374
|
| 26832417 |
Ma HT et al.:
TRIP13 Regulates Both the Activation and Inactivation of the Spindle-Assembly Checkpoint
Cell Rep
2016
14: 1086-1099
|
| 31337978 |
Gao Y et al. et al.:
Increased expression of TRIP13 drives the tumorigenesis of bladder cancer in association with the EGFR signaling pathway
Int. J. Biol. Sci.
2019
15: 1488-1499
|
| 27563873 |
Liang KL et al.:
Human TRIB2 Oscillates during the Cell Cycle and Promotes Ubiquitination and Degradation of CDC25C
|
| 25311538 |
Xu S et al.:
TRIB2 inhibits Wnt/beta-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, beta-TrCP, COP1 and Smurf1, in liver cancer cells
FEBS Lett.
2014
588: 4334-4341
|
| 23769673 |
Wang J et al.:
TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPalpha function
Mol. Cell
2013
51: 211-225
|
| 26804165 |
Yagi H et al.:
GEP oncogene promotes cell proliferation through YAP activation in ovarian cancer
Oncogene
2016
35: 4471-4480
|
| 22863277 |
Yu FX et al. et al.:
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling
Cell
2012
150: 780-791
|
| 9422511 |
Xie J et al. et al.:
Activating Smoothened mutations in sporadic basal-cell carcinoma
Nature
1998
391: 90-92
|
| 25278022 |
Schweiger S et al.:
The E3 ubiquitin ligase MID1 catalyzes ubiquitination and cleavage of Fu
J. Biol. Chem.
2014
289
|
| 31296839 |
Wu P et al.:
KHDRBS3 regulates the permeability of blood-tumor barrier via cDENND4C/miR-577 axis
Cell Death Dis
2019
10: 536
|
| 22246988 |
Liu W et al. et al.:
N-myc downstream regulated gene 1 modulates Wnt-beta-catenin signalling and pleiotropically suppresses metastasis
EMBO Mol Med
2012
4: 93-108
|
| 23526782 |
Malik YS et al.:
RING finger protein 10 regulates retinoic acid-induced neuronal differentiation and the cell cycle exit of P19 embryonic carcinoma cells
J. Cell. Biochem.
2013
114: 2007-2015
|
| 30008815 |
Tang Y et al.:
Fatty acid activation in carcinogenesis and cancer development: Essential roles of long-chain acyl-CoA synthetases
Oncol Lett
2018
16: 1390-1396
|
| 20844015 |
Dufu K et al.:
ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex
Genes Dev.
2010
24: 2043-2053
|
| 20573985 |
Yamazaki T et al.:
The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression
Mol. Biol. Cell
2010
21: 2953-2965
|
| 29131265 |
Xu HY et al. et al.:
Metformin reduces SATB2-mediated osteosarcoma stem cell-like phenotype and tumor growth via inhibition of N-cadherin/NF-kB signaling
Eur Rev Med Pharmacol Sci
2017
21: 4516-4528
|
| 25996149 |
LeBlanc ME et al. et al.:
Hepatoma-derived growth factor-related protein-3 is a novel angiogenic factor
PLoS ONE
2015
10
|
| 28334197 |
Chen Y et al.:
PPARalpha regulates tumor cell proliferation and senescence via a novel target gene carnitine palmitoyltransferase 1C
Carcinogenesis
2017
38: 474-483
|
| 23610451 |
Listerman I et al.:
The major reverse transcriptase-incompetent splice variant of the human telomerase protein inhibits telomerase activity but protects from apoptosis
Cancer Res.
2013
73: 2817-2828
|
| 31827232 |
Suzuki N et al.:
p53-induced ARVCF modulates the splicing landscape and supports the tumor suppressive function of p53
Oncogene
2020
39: 2202-2211
|
| 31966649 |
Su H et al.:
Upregulation of ATG4A promotes osteosarcoma cell epithelial-to-mesenchymal transition through the Notch signaling pathway
Int J Clin Exp Pathol
2017
10: 7975-7982
|
| 32194895 |
Li HR et al.:
Downregulation of SETBP1 promoted non-small cell lung cancer progression by inducing cellular EMT and disordered immune status
Am J Transl Res
2020
12: 447-462
|
| 23417712 |
Fontebasso AM et al. et al.:
Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas
Acta Neuropathol.
2013
125: 659-669
|
| 27518565 |
Park IY et al. et al.:
Dual Chromatin and Cytoskeletal Remodeling by SETD2
Cell
2016
166: 950-962
|
| 30683849 |
Abaev-Schneiderman E et al.:
SETD3 is a positive regulator of DNA-damage-induced apoptosis
Cell Death Dis
2019
10: 74
|
| 30442778 |
Kory N et al.:
SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism
|
| 27898674 |
Weston C et al.:
Aberrations in the Iron Regulatory Gene Signature Are Associated with Decreased Survival in Diffuse Infiltrating Gliomas
PLoS ONE
2016
11
|
| 28470949 |
Zhu Y et al.:
Loss of SH3GL2 promotes the migration and invasion behaviours of glioblastoma cells through activating the STAT3/MMP2 signalling
J. Cell. Mol. Med.
2017
21: 2685-2694
|
| 25728707 |
Maiti GP et al. et al.:
SNP rs1049430 in the 3-UTR of SH3GL2 regulates its expression: Clinical and prognostic implications in head and neck squamous cell carcinoma
Biochim. Biophys. Acta
2015
1852: 1059-1067
|
| 24736727 |
Yao Y et al.:
MiR-330-mediated regulation of SH3GL2 expression enhances malignant behaviors of glioblastoma stem cells by activating ERK and PI3K/AKT signaling pathways
PLoS ONE
2014
9
|
| 20512084 |
Shang C et al.:
SH3GL2 gene participates in MEK-ERK signal pathway partly by regulating EGFR in the laryngeal carcinoma cell line Hep2
Med. Sci. Monit.
2010
16: BR168-BR173
|
| 28655760 |
Li Z et al.:
Silencing of solute carrier family 13 member 5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells
J. Biol. Chem.
2017
292
|
| 10485450 |
Lin B et al.:
Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2
Cancer Res.
1999
59: 4180-4184
|
| 29757257 |
Tavares C et al.:
mTOR Pathway in Papillary Thyroid Carcinoma: Different Contributions of mTORC1 and mTORC2 Complexes for Tumor Behavior and SLC5A5 mRNA Expression
|
| 28824165 |
Vitte J et al.:
Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development
Nat Commun
2017
8: 300
|
| 24396461 |
Liu Q et al.:
Expression of SPRR3 is associated with tumor cell proliferation and invasion in glioblastoma multiforme
Oncol Lett
2014
7: 427-432
|
| 26286192 |
Lee JH et al.:
Involvement of SRSF11 in cell cycle-specific recruitment of telomerase to telomeres at nuclear speckles
Nucleic Acids Res.
2015
43: 8435-8451
|
| 30988100 |
Wawro M et al.:
ZC3H12B/MCPIP2, a new active member of the ZC3H12 family
RNA
2019
25: 840-856
|
| 19013223 |
Cho EY et al.:
Characterization of mouse synaptic vesicle-2-associated protein (Msvop) specifically expressed in the mouse central nervous system
Gene
2009
429: 44-48
|
| 15758025 |
Hirst J et al.:
The aftiphilin/p200/gamma-synergin complex
Mol. Biol. Cell
2005
16: 2554-2565
|
| 31792381 |
Zhu L et al.:
TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis
Nat. Cell Biol.
2019
21: 1604-1614
|
| 30509085 |
Zeng CX et al.:
TCF19 enhances cell proliferation in hepatocellular carcinoma by activating the ATK/FOXO1 signaling pathway
Neoplasma
2019
66: 46-53
|
| 22941191 |
Diskin SJ et al. et al.:
Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma
Nat. Genet.
2012
44: 1126-1130
|
| 31752241 |
Heo YR et al.:
TZAP Mutation Leads to Poor Prognosis of Patients with Breast Cancer (dagger)
|
| 24382891 |
Yoon JH et al.:
Human Kruppel-related 3 (HKR3) is a novel transcription activator of alternate reading frame (ARF) gene
J. Biol. Chem.
2014
289: 4018-4031
|
| 29254164 |
Choi SI et al.:
Osteopontin production by TM4SF4 signaling drives a positive feedback autocrine loop with the STAT3 pathway to maintain cancer stem cell-like properties in lung cancer cells
Oncotarget
2017
8
|
| 25344917 |
Choi SI et al.:
TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1
Oncotarget
2014
5: 9823-9837
|
| 21750032 |
Anderson KR et al.:
The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration
Development
2011
138: 3213-3224
|
| 27664330 |
Wang L et al.:
Exosomal proteins as prostate cancer biomarkers in urine: From mass spectrometry discovery to immunoassay-based validation
Eur J Pharm Sci
2017
98: 80-85
|
| 29515762 |
Meyer RD et al.:
TMIGD1 acts as a tumor suppressor through regulation of p21Cip1/p27Kip1 in renal cancer
Oncotarget
2017
9: 9672-9684
|
| 31318172 |
Wang J et al.:
Combined elevation of TRIB2 and MAP3K1 indicates poor prognosis and chemoresistance to temozolomide in glioblastoma
CNS Neurosci Ther
2020
26: 297-308
|
| 31525726 |
Rasha F et al.:
Mechanisms linking the renin-angiotensin system, obesity, and breast cancer
Endocr Relat Cancer
2019
26: R653-R672
|
| 31533816 |
Zhu MX et al.:
Elevated TRIP13 drives the AKT/mTOR pathway to induce the progression of hepatocellular carcinoma via interacting with ACTN4
J. Exp. Clin. Cancer Res.
2019
38: 409
|
| 31740732 |
Zhang G et al.:
TRIP13 promotes the cell proliferation, migration and invasion of glioblastoma through the FBXW7/c-MYC axis
Br. J. Cancer
2019
121: 1069-1078
|
| 30564064 |
Yao J et al.:
Silencing TRIP13 inhibits cell growth and metastasis of hepatocellular carcinoma by activating of TGF-beta1/smad3
Cancer Cell Int.
2018
18: 208
|
| 30720159 |
Zhou XY et al.:
TRIP13 promotes proliferation and invasion of epithelial ovarian cancer cells through Notch signaling pathway
Eur Rev Med Pharmacol Sci
2019
23: 522-529
|
| 32257385 |
Zhou ZJ et al.:
MACROD2 deficiency promotes hepatocellular carcinoma growth and metastasis by activating GSK-3beta/beta-catenin signaling
NPJ Genom Med
2020
5: 15
|
| 25232032 |
Hu Y et al.:
Bile acids regulate nuclear receptor (Nur77) expression and intracellular location to control proliferation and apoptosis
Mol. Cancer Res.
2015
13: 281-292
|
| 32277580 |
Cao Y et al.:
CDK4/6 inhibition suppresses tumour growth and enhances the effect of temozolomide in glioma cells
J. Cell. Mol. Med.
2020
24: 5135-5145
|
| 31773361 |
Huang L et al.:
Genetic Predisposition to Glioma Mediated by a MAPKAP1 Enhancer Variant
Cell. Mol. Neurobiol.
2020
40: 643-652
|
| 25394899 |
Ben Dhiab M et al.:
Methylation of miR124a-1, miR124a-2, and miR124a-3 in Hodgkin lymphoma
Tumour Biol.
2015
36: 1963-1971
|
| 29362722 |
Liu M et al.:
The Identification of Key Genes and Pathways in Glioma by Bioinformatics Analysis
J Immunol Res
2017
2017
|
| 22466964 |
den Besten W et al.:
NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway
Nat. Struct. Mol. Biol.
2012
19: 511-516
|
| 28923059 |
Mei Y et al.:
Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling
Cell Commun. Signal
2017
15: 34
|
| 24013638 |
Shah S et al. et al.:
A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia
Nat. Genet.
2013
45: 1226-1231
|
| 11556833 |
Anderson J et al.:
Detection of the PAX3-FKHR fusion gene in paediatric rhabdomyosarcoma: a reproducible predictor of outcome?
Br. J. Cancer
2001
85: 831-835
|
| 30323224 |
Deng Q et al.:
PHF19 promotes the proliferation, migration, and chemosensitivity of glioblastoma to doxorubicin through modulation of the SIAH1/beta-catenin axis
Cell Death Dis
2018
9: 1049
|
| 26551668 |
Mahamdallie SS et al. et al.:
Mutations in the transcriptional repressor REST predispose to Wilms tumor
Nat. Genet.
2015
47: 1471-1474
|
| 28886307 |
Zhang JW et al.:
Pleckstrin homology-like domain family B member 1 rs498872 polymorphism and glioma risk in Chinese Han population
Cell. Mol. Biol. (Noisy-le-grand)
2017
63: 7-9
|
| 30868356 |
Kim LH et al.:
A PHLDB1 variant associated with the nonfunctional pituitary adenoma
J. Neurooncol.
2019
142: 223-229
|
| 17332740 |
Schmidt A et al.:
Rho GTPases regulate PRK2/PKN2 to control entry into mitosis and exit from cytokinesis
EMBO J.
2007
26: 1624-1636
|
| 32423798 |
Tan G et al.:
PLA2G10 facilitates the cell-cycle progression of soft tissue leiomyosarcoma cells at least by elevating cyclin E1/CDK2 expression
Biochem. Biophys. Res. Commun.
2020
527: 525-531
|
| 30887697 |
Zhang L et al.:
PMEPA1 induces EMT via a non-canonical TGF-beta signalling in colorectal cancer
J. Cell. Mol. Med.
2019
23: 3603-3615
|
| 30890370 |
Amalia R et al.:
TMEPAI/PMEPA1 inhibits Wnt signaling by regulating beta-catenin stability and nuclear accumulation in triple negative breast cancer cells
Cell. Signal.
2019
59: 24-33
|
| 29945888 |
Huang YH et al. et al.:
POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer
Genes Dev.
2018
32: 915-928
|
| 23087057 |
Kalev P et al.:
Loss of PPP2R2A inhibits homologous recombination DNA repair and predicts tumor sensitivity to PARP inhibition
Cancer Res.
2012
72: 6414-6424
|
| 29178343 |
Moriya C et al.:
PRDM14 directly interacts with heat shock proteins HSP90alpha and glucose-regulated protein 78
Cancer Sci.
2018
109: 373-383
|
| 30785086 |
Chen YF et al.:
miR-125b suppresses oral oncogenicity by targeting the anti-oxidative gene PRXL2A
Redox Biol
2019
22
|
| 21733561 |
An CH et al.:
Frameshift mutations of vacuolar protein sorting genes in gastric and colorectal cancers with microsatellite instability
Hum. Pathol.
2012
43: 40-47
|
| 32351547 |
Zhang M et al.:
Novel Immune-Related Gene Signature for Risk Stratification and Prognosis of Survival in Lower-Grade Glioma
Front Genet
2020
11: 363
|
| 30607824 |
Zhu B et al.:
Association of PTTG1 polymorphism rs1895320, rs2910200 and rs6882742 with non-functioning pituitary adenomas in Chinese Han population: a case-control study
Metab Brain Dis
2019
34: 841-846
|
| 22816789 |
Vasiljevic A et al.:
Molecular characterization of central neurocytomas: potential markers for tumor typing and progression
Neuropathology
2013
33: 149-161
|
| 26264222 |
Zheng Y et al.:
FoxM1 transactivates PTTG1 and promotes colorectal cancer cell migration and invasion
BMC Med Genomics
2015
8: 49
|
| 31118763 |
Chen Y et al.:
WFDC2 contributes to epithelial-mesenchymal transition (EMT) by activating AKT signaling pathway and regulating MMP-2 expression
Cancer Manag Res
2019
11: 2415-2424
|
| 31103822 |
Zhang Y et al.:
WD repeat and SOCS box containing protein 2 in the proliferation, cycle progression, and migration of melanoma cells
Biomed. Pharmacother.
2019
116
|
| 23902685 |
Jacob A et al.:
Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells
J. Cell. Sci.
2013
126: 4647-4658
|
| 17121879 |
Ura K et al.:
Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma
Clin. Cancer Res.
2006
12: 6611-6616
|
| 31839818 |
Chen Z et al.:
RCC2 promotes breast cancer progression through regulation of Wnt signaling and inducing EMT
J Cancer
2019
10: 6837-6847
|
| 10790369 |
Balda MS et al.:
The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression
EMBO J.
2000
19: 2024-2033
|
| 16508013 |
Sourisseau T et al.:
Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA
Mol. Cell. Biol.
2006
26: 2387-2398
|
| 20133480 |
Lima WR et al. et al.:
ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells
J. Am. Soc. Nephrol.
2010
21: 478-488
|
| 18718466 |
Yoshida Y et al. et al.:
YIPF5 and YIF1A recycle between the ER and the Golgi apparatus and are involved in the maintenance of the Golgi structure
Exp. Cell Res.
2008
314: 3427-3443
|
| 19509059 |
Kano F et al.:
Yip1A regulates the COPI-independent retrograde transport from the Golgi complex to the ER
J. Cell. Sci.
2009
122: 2218-2227
|
| 28809393 |
Hsu PJ et al. et al.:
Ythdc2 is an N(6)-methyladenosine binding protein that regulates mammalian spermatogenesis
Cell Res.
2017
27: 1115-1127
|
| 24269672 |
Tanabe A et al.:
Transcriptional machinery of TNF-alpha-inducible YTH domain containing 2 (YTHDC2) gene
Gene
2014
535: 24-32
|
| 19144824 |
Planey SL et al.:
Palmitoylation of cytoskeleton associated protein 4 by DHHC2 regulates antiproliferative factor-mediated signaling
Mol. Biol. Cell
2009
20: 1454-1463
|
| 29221144 |
Sreedhar A et al.:
UCP2 overexpression enhanced glycolysis via activation of PFKFB2 during skin cell transformation
Oncotarget
2017
8
|
| 26549646 |
Nishan U et al.:
New transcription factors involved with postnatal ventral prostate gland development in male Wistar rats during the first week
Life Sci.
2015
143: 168-173
|
| 28258171 |
Shahi P et al.:
ZNF503/Zpo2 drives aggressive breast cancer progression by down-regulation of GATA3 expression
Proc. Natl. Acad. Sci. U.S.A.
2017
114: 3169-3174
|
| 25538248 |
Shahi P et al.:
The Transcriptional Repressor ZNF503/Zeppo2 Promotes Mammary Epithelial Cell Proliferation and Enhances Cell Invasion
J. Biol. Chem.
2015
290: 3803-3813
|
| 25422082 |
Cui J et al. et al.:
Comprehensive characterization of the genomic alterations in human gastric cancer
Int. J. Cancer
2015
137: 86-95
|
| 30045876 |
Yang SF et al.:
Structural and functional characterization of the RBBP4-ZNF827 interaction and its role in NuRD recruitment to telomeres
Biochem. J.
2018
475: 2667-2679
|
| 24101726 |
Yang M et al. et al.:
A double-negative feedback loop between Wnt-beta-catenin signaling and HNF4alpha regulates epithelial-mesenchymal transition in hepatocellular carcinoma
J. Cell. Sci.
2013
126: 5692-5703
|
| 29673126 |
Chen YL et al.:
Overexpression of HACE1 in gastric cancer inhibits tumor aggressiveness by impeding cell proliferation and migration
Cancer Med
2018
7: 2472-2484
|
| 22614015 |
Castillo-Lluva S et al.:
The tumour suppressor HACE1 controls cell migration by regulating Rac1 degradation
Oncogene
2013
32: 1735-1742
|
| 25684205 |
Genau HM et al.:
CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling
Mol. Cell
2015
57: 995-1010
|
| 31941533 |
Quan M et al.:
Lysine demethylase 2 (KDM2B) regulates hippo pathway via MOB1 to promote pancreatic ductal adenocarcinoma (PDAC) progression
J. Exp. Clin. Cancer Res.
2020
39: 13
|
| 31402945 |
Pang G et al.:
Mitofusin 2 inhibits bladder cancer cell proliferation and invasion via the Wnt/beta-catenin pathway
Oncol Lett
2019
18: 2434-2442
|
| 25332232 |
Zaru R et al.:
Structural and functional basis for p38-MK2-activated Rsk signaling in toll-like receptor-stimulated dendritic cells
Mol. Cell. Biol.
2015
35: 132-140
|
| 32291963 |
Jing T et al.:
MAST1 modulates neuronal differentiation and cell cycle exit via P27 in neuroblastoma cells
FEBS Open Bio
2020
10: 1104-1114
|
| 29310626 |
Akiva I et al.:
MGAT1 is a novel transcriptional target of Wnt/beta-catenin signaling pathway
BMC Cancer
2018
18: 60
|
| 22489821 |
Ding W et al.:
NDRG4 is downregulated in glioblastoma and inhibits cell proliferation
OMICS
2012
16: 263-267
|
| 27840993 |
Xu X et al.:
NTN4 is associated with breast cancer metastasis via regulation of EMT-related biomarkers
Oncol. Rep.
2017
37: 449-457
|
| 31997489 |
Ni Q et al.:
Epithelial V-like antigen 1 promotes hepatocellular carcinoma growth and metastasis via the ERBB-PI3K-AKT pathway
Cancer Sci.
2020
111: 1500-1513
|
| 32749065 |
author information missing
article information missing
|
| 23754390 |
Rochin L et al.:
BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells
Proc. Natl. Acad. Sci. U.S.A.
2013
110
|
| 28724603 |
Wang JJ et al.:
Effects of microRNA-136 on melanoma cell proliferation, apoptosis, and epithelial-mesenchymal transition by targetting PMEL through the Wnt signaling pathway
|
| 29393474 |
Zhao J et al.:
REC8 inhibits EMT by downregulating EGR1 in gastric cancer cells
Oncol. Rep.
2018
39: 1583-1590
|
| 26472282 |
Liu D et al.:
REC8 is a novel tumor suppressor gene epigenetically robustly targeted by the PI3K pathway in thyroid cancer
Oncotarget
2015
6
|
| 26323264 |
Hu Y et al.:
RGS22 inhibits pancreatic adenocarcinoma cell migration through the G12/13 alpha subunit/F-actin pathway
Oncol. Rep.
2015
34: 2507-2514
|
| 23128396 |
Conforti F et al.:
PIR2/Rnf144B regulates epithelial homeostasis by mediating degradation of p21WAF1 and p63
Oncogene
2013
32: 4758-4765
|
| 26058078 |
Nguyen LT et al.:
ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors
Cancer Cell
2015
27: 797-808
|
| 16084624 |
Oba-Shinjo SM et al.:
Identification of novel differentially expressed genes in human astrocytomas by cDNA representational difference analysis
Brain Res. Mol. Brain Res.
2005
140: 25-33
|
| 32232887 |
Li YQ et al.:
FNDC3B 3-UTR shortening escapes from microRNA-mediated gene repression and promotes nasopharyngeal carcinoma progression
Cancer Sci.
2020
111: 1991-2003
|
| 31489998 |
Wang J et al.:
Guanylate-binding protein-2 inhibits colorectal cancer cell growth and increases the sensitivity to paclitaxel of paclitaxel-resistant colorectal cancer cells by interfering Wnt signaling
J. Cell. Biochem.
2020
121: 1250-1259
|
| 25076857 |
Wang Q et al.:
SAMD9L inactivation promotes cell proliferation via facilitating G1-S transition in hepatitis B virus-associated hepatocellular carcinoma
Int. J. Biol. Sci.
2014
10: 807-816
|
| 32325008 |
Jiang Y et al. et al.:
GPR39 Overexpression in OSCC Promotes YAP-Sustained Malignant Progression
J. Dent. Res.
2020
99: 949-958
|
| 24633354 |
Bassilana F et al. et al.:
Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39
Nat. Chem. Biol.
2014
10: 343-349
|
| 28109176 |
Kohashi K et al.:
Oncogenic roles of SMARCB1/INI1 and its deficient tumors
Cancer Sci.
2017
108: 547-552
|
| 26783088 |
Lim SM et al.:
The structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a--an acid sphingomyelinase homologue with a novel nucleotide hydrolase activity
FEBS J.
2016
283: 1107-1123
|
| 31911856 |
Yan B et al.:
SORBS2, mediated by MEF2D, suppresses the metastasis of human hepatocellular carcinoma by inhibitiing the c-Abl-ERK signaling pathway
Am J Cancer Res
2019
9: 2706-2718
|
| 15659545 |
Cestra G et al.:
The Abl/Arg substrate ArgBP2/nArgBP2 coordinates the function of multiple regulatory mechanisms converging on the actin cytoskeleton
Proc. Natl. Acad. Sci. U.S.A.
2005
102: 1731-1736
|
| 12475393 |
Soubeyran P et al.:
Cbl-ArgBP2 complex mediates ubiquitination and degradation of c-Abl
Biochem. J.
2003
370: 29-34
|
| 29673586 |
Zhou Z et al.:
Methylation-induced silencing of SPG20 facilitates gastric cancer cell proliferation by activating the EGFR/MAPK pathway
Biochem. Biophys. Res. Commun.
2018
500: 411-417
|
| 30832559 |
Ren F et al.:
SPOCK2 Affects the Biological Behavior of Endometrial Cancer Cells by Regulation of MT1-MMP and MMP2
|
| 29361551 |
Lyraki R et al.:
Characterization of a novel RP2-OSTF1 interaction and its implication for actin remodelling
|
| 11477086 |
Meng X et al.:
Suppressor of fused negatively regulates beta-catenin signaling
J. Biol. Chem.
2001
276
|
| 29231998 |
Bhardwaj D et al.:
Phosphorylated Tyr142 beta-catenin localizes to centrosomes and is regulated by Syk
J. Cell. Biochem.
2018
119: 3632-3640
|
| 28339031 |
Cao Y et al.:
p53-inducible long non-coding RNA PICART1 mediates cancer cell proliferation and migration
Int. J. Oncol.
2017
50: 1671-1682
|
| 31548378 |
Yin Y et al.:
The FBXW2-MSX2-SOX2 axis regulates stem cell property and drug resistance of cancer cells
Proc Natl Acad Sci U S A
2019
116
|
| 32155954 |
Belisario DC et al.:
ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma
|
| 27396341 |
Beck TN et al. et al.:
Anti-Mullerian Hormone Signaling Regulates Epithelial Plasticity and Chemoresistance in Lung Cancer
Cell Rep
2016
16: 657-671
|
| 18235225 |
Hansen CA et al.:
A functional link between the human cell cycle-regulatory phosphatase Cdc14A and the atypical mitogen-activated kinase Erk3
Cell Cycle
2008
7: 325-334
|
| 17353904 |
Sims-Mourtada J et al.:
Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport
Oncogene
2007
26: 5674-5679
|
| 10837354 |
Bello-Reuss E et al.:
Role of multidrug resistance P-glycoprotein in the secretion of aldosterone by human adrenal NCI-H295 cells
Am J Physiol Cell Physiol
2000
278
|
| 24680817 |
Fonovic M et al.:
Cysteine cathepsins and extracellular matrix degradation
Biochim Biophys Acta
2014
1840: 2560-2570
|
| 20731543 |
Gocheva V et al.:
Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer
Biol Chem
2010
391: 937-945
|
| 25911611 |
Meguenani M et al.:
Junctional adhesion molecule B interferes with angiogenic VEGF/VEGFR2 signaling
FASEB J
2015
29: 3411-3425
|
| 28837538 |
Barrett CD et al.:
Human neutrophil elastase mediates fibrinolysis shutdown through competitive degradation of plasminogen and generation of angiostatin
J Trauma Acute Care Surg
2017
83: 1053-1061
|
| 10229661 |
Stack MS et al.:
Angiostatin inhibits endothelial and melanoma cellular invasion by blocking matrix-enhanced plasminogen activation
Biochem J
1999
340: ( Pt 1) 77-84
|
| 12453439 |
Tuszynski GP et al.:
Angiostatin binds to tyrosine kinase substrate annexin II through the lysine-binding domain in endothelial cells
Microvasc Res
2002
64: 448-462
|
| 21217776 |
Wu SM et al.:
Cathepsin H regulated by the thyroid hormone receptors associate with tumor invasion in human hepatoma cells
Oncogene
2011
30: 2057-2069
|
| 17601559 |
Amini Nik S et al.:
TGF-beta modulates beta-Catenin stability and signaling in mesenchymal proliferations
Exp Cell Res
2007
313: 2887-2895
|
| 21618524 |
Zhang C et al.:
IGF binding protein-6 expression in vascular endothelial cells is induced by hypoxia and plays a negative role in tumor angiogenesis
Int J Cancer
2012
130: 2003-2012
|
| 10195688 |
Mullis PE et al.:
Regulation of human growth hormone receptor gene transcription by triiodothyronine (T3)
Mol Cell Endocrinol
1999
147: 17-25
|
| 10978336 |
Pombo PM et al.:
Transcriptional repression of neurotrophin receptor trkB by thyroid hormone in the developing rat brain
J Biol Chem
2000
275
|
| 24623448 |
Schon S et al.:
beta-catenin regulates NF-kappaB activity via TNFRSF19 in colorectal cancer cells
Int J Cancer
2014
135: 1800-1811
|
| 12819200 |
Ishida T et al.:
Targeted disruption of endothelial cell-selective adhesion molecule inhibits angiogenic processes in vitro and in vivo
J Biol Chem
2003
278
|
| 30145833 |
Kirchmeyer M et al.:
Cytokine-mediated modulation of the hepatic miRNome: miR-146b-5p is an IL-6-inducible miRNA with multiple targets
J Leukoc Biol
2018
104: 987-1002
|
| 31208444 |
Yang Q et al.:
Minichromosome maintenance 3 promotes hepatocellular carcinoma radioresistance by activating the NF-kappaB pathway
J Exp Clin Cancer Res
2019
38: 263
|
| 23063586 |
Kattamuri C et al.:
Members of the DAN family are BMP antagonists that form highly stable noncovalent dimers
J Mol Biol
2012
424: 313-327
|
| 24947526 |
Ghim J et al. et al.:
Endothelial deletion of phospholipase D2 reduces hypoxic response and pathological angiogenesis
Arterioscler Thromb Vasc Biol
2014
34: 1697-1703
|
| 27672444 |
Yuzugullu H et al.:
NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathways
Cell Discov
2016
2: 16030
|
| 17374610 |
Martens LK et al.:
Hypoxia-inducible factor-1 (HIF-1) is a transcriptional activator of the TrkB neurotrophin receptor gene
J Biol Chem
2007
282
|
| 31934129 |
Duan B et al.:
Overexpression of ERBB3 promotes proliferation, migration, and angiogenesis in nasopharyngeal carcinoma
Int J Clin Exp Pathol
2019
12: 2931-2940
|
| 29904943 |
Bhattacharya R et al.:
FGF9-induced ovarian cancer cell invasion involves VEGF-A/VEGFR2 augmentation by virtue of ETS1 upregulation and metabolic reprogramming
J Cell Biochem
2018
119: 8174-8189
|
| 10854539 |
Temmim L et al.:
Expression of growth hormone receptor in human liposarcomas and lipomas
Oncol Rep
2000
7: 757-760
|
| 30229899 |
Zhu J et al.:
MicroRNA-363 inhibits angiogenesis, proliferation, invasion, and migration of renal cell carcinoma via inactivation of the Janus tyrosine kinases 2-signal transducers and activators of transcription 3 axis by suppressing growth hormone receptor gene
J Cell Physiol
2019
234: 2581-2592
|
| 23233738 |
Das SK et al. et al.:
MDA-9/syntenin and IGFBP-2 promote angiogenesis in human melanoma
Cancer Res
2013
73: 844-854
|
| 26693061 |
Yang D et al.:
Progranulin promotes colorectal cancer proliferation and angiogenesis through TNFR2/Akt and ERK signaling pathways
Am J Cancer Res
2015
5: 3085-3097
|
| 11083468 |
Soltys BJ et al.:
Localization of P32 protein (gC1q-R) in mitochondria and at specific extramitochondrial locations in normal tissues
Histochem Cell Biol
2000
114: 245-255
|
| 24520092 |
Gala K et al.:
Molecular pathways: HER3 targeted therapy
Clin Cancer Res
2014
20: 1410-1416
|
| 29735548 |
Deng C et al.:
TNFRSF19 Inhibits TGFbeta Signaling through Interaction with TGFbeta Receptor Type I to Promote Tumorigenesis
Cancer Res
2018
78: 3469-3483
|
| 19465692 |
Lee TY et al.:
Angiostatin regulates the expression of antiangiogenic and proapoptotic pathways via targeted inhibition of mitochondrial proteins
Blood
2009
114: 1987-1998
|
| 21821709 |
Huynh H et al.:
IGF binding protein 2 supports the survival and cycling of hematopoietic stem cells
Blood
2011
118: 3236-3243
|
| 23611775 |
Gao YH et al.:
Hypoxia-inducible factor 1alpha mediates the down-regulation of superoxide dismutase 2 in von Hippel-Lindau deficient renal clear cell carcinoma
Biochem Biophys Res Commun
2013
435: 46-51
|
| 15064403 |
Li C et al.:
Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells
Proc Natl Acad Sci U S A
2004
101: 5571-5576
|
| 12738778 |
Oberst MD et al.:
The activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitor
J Biol Chem
2003
278
|
| 21554982 |
Record M et al.:
Bis (monoacylglycero) phosphate interfacial properties and lipolysis by pancreatic lipase-related protein 2, an enzyme present in THP-1 human monocytes
Biochim Biophys Acta
2011
1811: 419-430
|
| 17010228 |
Elinson N et al.:
Leptin directly regulates exocrine pancreas lipase and two related proteins in the rat
Br J Nutr
2006
96: 691-696
|
| 10219059 |
Kataoka H et al.:
Distribution of hepatocyte growth factor activator inhibitor type 1 (HAI-1) in human tissues. Cellular surface localization of HAI-1 in simple columnar epithelium and its modulated expression in injured and regenerative tissues
J Histochem Cytochem
1999
47: 673-682
|
| 29723415 |
Gough RE et al.:
The tale of two talins - two isoforms to fine-tune integrin signalling
FEBS Lett
2018
592: 2108-2125
|
| 32198023 |
Baster Z et al.:
Talin2 mediates secretion and trafficking of matrix metallopeptidase 9 during invadopodium formation
Biochim Biophys Acta Mol Cell Res
2020
1867
|
| 11000516 |
McCulloch DR et al.:
The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone
Mol Cell Endocrinol
2000
167: 11-21
|
| 24332999 |
Patel VB et al.:
Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: a positive feedback mechanism in the RAS
J Mol Cell Cardiol
2014
66: 167-176
|
| 19595713 |
Liu C et al.:
TACE-mediated ectodomain shedding of the type I TGF-beta receptor downregulates TGF-beta signaling
Mol Cell
2009
35: 26-36
|
| 22012253 |
Chaiwatanasirikul KA et al.:
The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60
Cell Death Dis
2011
2: e219
|
| 28177523 |
Lin Y et al.:
Association between genetic variation within vitamin D receptor-DNA binding sites and risk of basal cell carcinoma
Int J Cancer
2017
140: 2085-2091
|
| 19646959 |
Hiroi M et al.:
STAT1 represses hypoxia-inducible factor-1-mediated transcription
Biochem Biophys Res Commun
2009
387: 806-810
|
| 12927788 |
Leonard D et al.:
hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing
Biochem Biophys Res Commun
2003
308: 793-801
|
| 19894109 |
Iacopetta D et al.:
SLC37A1 gene expression is up-regulated by epidermal growth factor in breast cancer cells
Breast Cancer Res Treat
2010
122: 755-764
|
| 15125840 |
Jiang Y et al.:
Involvement of transcription termination factor 2 in mitotic repression of transcription elongation
Mol Cell
2004
14: 375-385
|
| 19633697 |
Zhang N et al.:
Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint
EMBO Rep
2009
10: 1029-1035
|
| 15210935 |
Cortez D et al.:
Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases
Proc Natl Acad Sci U S A
2004
101
|
| 32984322 |
Makinwa Y et al.:
PP2A Regulates Phosphorylation-Dependent Isomerization of Cytoplasmic and Mitochondrial-Associated ATR by Pin1 in DNA Damage Responses
Front Cell Dev Biol
2020
8: 813
|
| 33344452 |
Qi T et al.:
Super-Enhancer Associated Five-Gene Risk Score Model Predicts Overall Survival in Multiple Myeloma Patients
Front Cell Dev Biol
2020
8
|
| 33292758 |
Alkan HF et al.:
Deficiency of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis
Cancer Metab
2020
8: 26
|
| 19966785 |
Ostrowski M et al. et al.:
Rab27a and Rab27b control different steps of the exosome secretion pathway
Nat Cell Biol
2010
12: 19-30;suppp1-13
|
| 33554392 |
Kim HJ et al.:
SLAC2B-dependent microtubule acetylation regulates extracellular matrix-mediated intracellular TM4SF5 traffic to the plasma membranes
FASEB J
2021
35
|
| 24768165 |
Yu J et al.:
WLS retrograde transport to the endoplasmic reticulum during Wnt secretion
Dev Cell
2014
29: 277-291
|
| 31205537 |
Li G et al.:
LMO1 Super-Enhancer rs2168101 G>T Polymorphism Reduces Wilms Tumor Risk
J Cancer
2019
10: 1808-1813
|
| 31830377 |
Hashemi M et al.:
LMO1 polymorphisms and the risk of neuroblastoma: Assessment of meta-analysis of case-control studies
J Cell Mol Med
2020
24: 1160-1168
|
| 33042263 |
Liu XY et al.:
SYTL4 downregulates microtubule stability and confers paclitaxel resistance in triple-negative breast cancer
Theranostics
2020
10
|
| 26602861 |
Maghsoudlou A et al.:
RNF121 Inhibits Angiogenic Growth Factor Signaling by Restricting Cell Surface Expression of VEGFR-2
Traffic
2016
17: 289-300
|
| 24928685 |
author information missing
Really interesting new gene finger protein 121 is a novel Golgi-localized membrane protein that regulates apoptosis
Acta Biochim Biophys Sin (Shanghai)
2014
46: 668-674
|
| 21976065 |
Ito K et al.:
The role of the CNOT1 subunit of the CCR4-NOT complex in mRNA deadenylation and cell viability
Protein Cell
2011
2: 755-763
|
| 19558367 |
Lau NC et al.:
Human Ccr4-Not complexes contain variable deadenylase subunits
Biochem J
2009
422: 443-453
|
| 21233283 |
Mittal S et al.:
The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence
Mol Biol Cell
2011
22: 748-758
|
| 22000013 |
Tay Y et al. et al.:
Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
Cell
2011
147: 344-357
|
| 22614729 |
Maragozidis P et al.:
Alterations of deadenylase expression in acute leukemias: evidence for poly(a)-specific ribonuclease as a potential biomarker
Acta Haematol
2012
128: 39-46
|
| 32322062 |
Xu D et al. et al.:
The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis
Nature
2020
580: 530-535
|
| 19219026 |
Gao P et al.:
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
Nature
2009
458: 762-765
|
| 23334421 |
Jiang P et al.:
Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence
Nature
2013
493: 689-693
|
| 15920557 |
Martins C et al.:
PLAG1 gene alterations in salivary gland pleomorphic adenoma and carcinoma ex-pleomorphic adenoma: a combined study using chromosome banding, in situ hybridization and immunocytochemistry
Mod Pathol
2005
18: 1048-1055
|
| 16108035 |
Zhao X et al.:
Wnt pathway is involved in pleomorphic adenomas induced by overexpression of PLAG1 in transgenic mice
Int J Cancer
2006
118: 643-648
|
| 18593907 |
Pai R et al.:
Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling
Cancer Res
2008
68: 5086-5095
|
| 18172165 |
Mullen TE et al.:
Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5 to 3 and 3 to 5
Genes Dev
2008
22: 50-65
|
| 29233996 |
Yang L et al.:
PEPD is a pivotal regulator of p53 tumor suppressor
Nat Commun
2017
8: 2052
|
| 24810047 |
Yang L et al.:
Identification of prolidase as a high affinity ligand of the ErbB2 receptor and its regulation of ErbB2 signaling and cell growth
Cell Death Dis
2014
5: e1211
|
| 23212918 |
Yang L et al.:
Prolidase directly binds and activates epidermal growth factor receptor and stimulates downstream signaling
J Biol Chem
2013
288: 2365-2375
|
| 24719332 |
Breuer R et al.:
The protein phosphatase 2A regulatory subunit B56gamma mediates suppression of T cell receptor (TCR)-induced nuclear factor-kappaB (NF-kappaB) activity
J Biol Chem
2014
289
|
| 20444422 |
Hahn K et al.:
PP2A regulatory subunit PP2A-B counteracts S6K phosphorylation
Cell Metab
2010
11: 438-444
|
| 18235218 |
Arroyo JD et al.:
Liprin alpha1 interacts with PP2A B56gamma
Cell Cycle
2008
7: 525-532
|
| 17967874 |
Shouse GP et al.:
Serine 15 phosphorylation of p53 directs its interaction with B56gamma and the tumor suppressor activity of B56gamma-specific protein phosphatase 2A
Mol Cell Biol
2008
28: 448-456
|
| 29242231 |
Guna A et al.:
The ER membrane protein complex is a transmembrane domain insertase
Science
2018
359: 470-473
|
| 31484065 |
Tian S et al.:
Proteomic Analysis Identifies Membrane Proteins Dependent on the ER Membrane Protein Complex
Cell Rep
2019
28: 2517-2526.e5
|
| 23182941 |
Li Y et al.:
A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy
Autophagy
2013
9: 150-163
|
| 32529408 |
author information missing
article information missing
|
| 24089205 |
author information missing
article information missing
|
| 21888893 |
author information missing
article information missing
|
| 26109723 |
author information missing
article information missing
|
| 32561851 |
author information missing
article information missing
|
| 21543332 |
author information missing
article information missing
|
| 34439323 |
author information missing
article information missing
|
| 24833526 |
author information missing
article information missing
|
| 24218572 |
author information missing
article information missing
|
| 25538220 |
author information missing
article information missing
|
| 30258100 |
author information missing
article information missing
|
| 24732912 |
author information missing
article information missing
|
| 18685082 |
author information missing
article information missing
|
| 26983758 |
author information missing
article information missing
|
| 18377426 |
author information missing
article information missing
|
| 23591815 |
author information missing
article information missing
|
| 34518538 |
author information missing
article information missing
|
| 21826244 |
author information missing
article information missing
|
| 25918224 |
author information missing
article information missing
|
| 23394947 |
author information missing
article information missing
|
| 26711178 |
author information missing
article information missing
|
| 30447097 |
author information missing
article information missing
|
| 20372782 |
author information missing
article information missing
|
| 17130457 |
author information missing
article information missing
|
| 22761335 |
author information missing
article information missing
|
| 16033423 |
author information missing
article information missing
|
| 19121354 |
author information missing
article information missing
|
| 26731475 |
author information missing
article information missing
|
| 32821163 |
author information missing
article information missing
|
| 25891951 |
author information missing
article information missing
|
| 21562571 |
author information missing
article information missing
|
| 22653145 |
author information missing
article information missing
|
| 24702277 |
author information missing
article information missing
|
| 28548937 |
author information missing
article information missing
|
| 22665267 |
author information missing
article information missing
|
| 17804717 |
author information missing
article information missing
|
| 31631010 |
author information missing
article information missing
|
| 31402609 |
author information missing
article information missing
|
| 22365974 |
author information missing
article information missing
|
| 33392180 |
author information missing
article information missing
|
| 28739689 |
author information missing
article information missing
|
| 35117340 |
author information missing
article information missing
|
| 32945370 |
author information missing
article information missing
|
| 9140396 |
author information missing
article information missing
|
| 17030811 |
author information missing
article information missing
|
| 12097293 |
author information missing
article information missing
|
| 17054975 |
author information missing
article information missing
|
| 23737528 |
author information missing
article information missing
|
| 26375249 |
author information missing
article information missing
|
| 33147457 |
author information missing
article information missing
|
| 31819643 |
author information missing
article information missing
|
| 35004310 |
author information missing
article information missing
|
| 31375012 |
author information missing
article information missing
|
| 16651416 |
author information missing
article information missing
|
| 33615655 |
author information missing
article information missing
|
| 15679048 |
author information missing
article information missing
|
| 31269763 |
author information missing
article information missing
|
| 37457732 |
author information missing
article information missing
|
| 30140388 |
author information missing
article information missing
|
| 32759795 |
author information missing
article information missing
|
| 31219645 |
author information missing
article information missing
|
| 19060924 |
author information missing
article information missing
|
| 22496359 |
author information missing
article information missing
|
| 26446840 |
author information missing
article information missing
|
| 10546001 |
Heaney AP et al.:
Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis
Nat. Med.
1999
5: 1317-1321
|
| 19668232 |
Chan CB et al.:
NGF inhibits human leukemia proliferation by downregulating cyclin A1 expression through promoting acinus/CtBP2 association
Oncogene
2009
28: 3825-3836
|
| 10845904 |
Khanna-Gupta A et al.:
Sp1 and C/EBP are necessary to activate the lactoferrin gene promoter during myeloid differentiation
Blood
2000
95: 3734-3741
|
| 27013649 |
Novakova M et al.:
Loss of B cells and their precursors is the most constant feature of GATA-2 deficiency in childhood myelodysplastic syndrome
Haematologica
2016
101: 707-716
|
| 12892713 |
Ishida D et al.:
Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice
Cancer Cell
2003
4: 55-65
|
| 30309654 |
Yonezawa T et al.:
The ubiquitin ligase RNF38 promotes RUNX1 ubiquitination and enhances RUNX1-mediated suppression of erythroid transcription program
Biochem. Biophys. Res. Commun.
2018
505: 905-909
|
| 31845480 |
Borna S et al. et al.:
Transmembrane adaptor protein WBP1L regulates CXCR4 signalling and murine haematopoiesis
J. Cell. Mol. Med.
2020
24: 1980-1992
|
| 27540136 |
Neveu B et al.:
CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia
Haematologica
2016
101: 1534-1543
|
| 21263198 |
Lizcano F et al.:
Thyroid hormone therapy modulates hypothalamo-pituitary-adrenal axis
Endocr. J.
2011
58: 137-142
|
| 22641097 |
Niu DF et al.:
Transcription factor Runx2 is a regulator of epithelial-mesenchymal transition and invasion in thyroid carcinomas
Lab. Invest.
2012
92: 1181-1190
|
| 26458316 |
author information missing
Trefoil factor 3 is required for differentiation of thyroid follicular cells and acts as a context-dependent tumor suppressor
Neoplasma
2015
62: 914-924
|
| 17875692 |
Pamidi A et al.:
Functional interplay of p53 and Mus81 in DNA damage responses and cancer.
Cancer Res.
2007
67: 8527-8535
|
| 21092550 |
Chen YH et al.:
[Regulation of Bub1 mRNA expression in endometrial carcinoma Ishikawa cells by estrogen and paclitaxel].
Zhonghua Fu Chan Ke Za Zhi
2010
45: 686-690
|
| 17507620 |
Tao MH et al.:
Polymorphisms in the CYP19A1 (aromatase) gene and endometrial cancer risk in Chinese women
Cancer Epidemiol. Biomarkers Prev.
2007
16: 943-949
|
| 18850582 |
Hrzenjak A et al.:
SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway
J. Pathol.
2008
216: 495-504
|
| 29467457 |
Park H et al.:
Adenylosuccinate lyase enhances aggressiveness of endometrial cancer by increasing killer cell lectin-like receptor C3 expression by fumarate
Lab. Invest.
2018
98: 449-461
|
| 20442286 |
Aryee DN et al.:
Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewings sarcoma cells in vitro
Cancer Res.
2010
70: 4015-4023
|
| 21798848 |
Miller S et al.:
Genome-wide molecular characterization of central nervous system primitive neuroectodermal tumor and pineoblastoma
Neuro-oncology
2011
13: 866-879
|
| 16270043 |
Marasca R et al.:
Gene expression profiling of acute promyelocytic leukaemia identifies two subtypes mainly associated with flt3 mutational status
Leukemia
2006
1: 103-114
|
| 17047052 |
Ng AP et al.:
Cleavage of misfolded nuclear receptor corepressor confers resistance to unfolded protein response-induced apoptosis
Cancer Res.
2006
66: 9903-9912
|
| 12958071 |
Garattini E et al. et al.:
ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis
Blood
2004
103: 194-207
|
| 20331975 |
Shen R et al.:
Epigenetic repression of microRNA-129-2 leads to overexpression of SOX4 in gastric cancer
Biochem. Biophys. Res. Commun.
2010
4: 1047-1052
|
| 25005785 |
Wang L et al.:
LZTFL1 suppresses gastric cancer cell migration and invasion through regulating nuclear translocation of beta-catenin
J. Cancer Res. Clin. Oncol.
2014
140: 1997-2008
|
| 24124332 |
Yim DH et al.:
ITGA1 polymorphisms and haplotypes are associated with gastric cancer risk in a Korean population
World J. Gastroenterol.
2013
35: 5870-5876
|
| 26060493 |
Park KK et al.:
Correlations of Human Epithelial Growth Factor Receptor 2 Overexpression with MUC2, MUC5AC, MUC6, p53, and Clinicopathological Characteristics in Gastric Cancer Patients with Curative Resection
Gastroenterol Res Pract
2015
2015
|
| 20062084 |
Mejias-Luque R et al.:
Inflammation modulates the expression of the intestinal mucins MUC2 and MUC4 in gastric tumors
Oncogene
2010
29: 1753-1762
|
| 18519687 |
Ganesan K et al.:
Inhibition of gastric cancer invasion and metastasis by PLA2G2A, a novel beta-catenin/TCF target gene
Cancer Res.
2008
68: 4277-4286
|
| 17938585 |
Shao XD et al.:
Expression and significance of HERG protein in gastric cancer
Cancer Biol. Ther.
2008
7: 45-50
|
| 25756516 |
Subbannayya Y et al.:
Calcium calmodulin dependent kinase kinase 2 - a novel therapeutic target for gastric adenocarcinoma
Cancer Biol. Ther.
2015
16: 336-345
|
| 26565812 |
Wang L et al.:
Overexpressed CISD2 has prognostic value in human gastric cancer and promotes gastric cancer cell proliferation and tumorigenesis via AKT signaling pathway
Oncotarget
2016
7: 3791-3805
|
| 29540196 |
Zheng CH et al. et al.:
CDK5RAP3 suppresses Wnt/beta-catenin signaling by inhibiting AKT phosphorylation in gastric cancer
J. Exp. Clin. Cancer Res.
2018
37: 59
|
| 30573971 |
Chen D et al.:
TRIM37 promotes cell invasion and metastasis by regulating SIP1-mediated epithelial-mesenchymal transition in gastric cancer
Onco Targets Ther
2018
11: 8803-8813
|
| 23554630 |
Liu L et al.:
Elevated expression of mature miR-21 and miR-155 in cancerous gastric tissues from Chinese patients with gastric cancer
J Biomed Res
2010
24: 187-197
|
| 30948703 |
Hao S et al.:
Identification of Key Genes and Circular RNAs in Human Gastric Cancer
Med. Sci. Monit.
2019
25: 2488-2504
|
| 32570120 |
Liu J et al.:
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/beta-catenin signaling pathways
Biomed. Pharmacother.
2020
129
|
| 30021604 |
Wang L et al.:
Paired box 8 suppresses tumor angiogenesis and metastasis in gastric cancer through repression of FOXM1 via induction of microRNA-612
J Exp Clin Cancer Res
2018
37: 159
|
| 29158006 |
Albi E et al.:
VDR independent induction of acid-sphingomyelinase by 1,23(OH)2 D3 in gastric cancer cells: Impact on apoptosis and cell morphology
Biochimie
2018
146: 35-42
|
| 33174370 |
Xu LL et al.:
M-Phase Phosphoprotein 9 upregulation associates with poor prognosis and activates mTOR signaling in gastric cancer
Kaohsiung J Med Sci
2021
37: 208-214
|
| 21480392 |
Goode EL et al.:
Xenobiotic-Metabolizing gene polymorphisms and ovarian cancer risk
Mol. Carcinog.
2011
50: 397-402
|
| 26695144 |
Li N et al.:
miR-494 suppresses tumor growth of epithelial ovarian carcinoma by targeting IGF1R
Tumour Biol.
2016
37: 7767-7776
|
| 22429801 |
Haslehurst AM et al. et al.:
EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer
BMC Cancer
2012
12: 91
|
| 28679402 |
Chen Y et al.:
WAP four-disulfide core domain protein 2 promotes metastasis of human ovarian cancer by regulation of metastasis-associated genes
J Ovarian Res
2017
10: 40
|
| 25304686 |
Zhang S et al.:
Clinically relevant microRNAs in ovarian cancer
Mol. Cancer Res.
2015
13: 393-401
|
| 30108103 |
Pisanic TR 2nd et al.:
Methylomic Analysis of Ovarian Cancers Identifies Tumor-Specific Alterations Readily Detectable in Early Precursor Lesions
Clin. Cancer Res.
2018
24: 6536-6547
|
| 17303177 |
Cai LY et al.:
Identification of PRTFDC1 silencing and aberrant promoter methylation of GPR150, ITGA8 and HOXD11 in ovarian cancers
Life Sci.
2007
80: 1458-1465
|
| 19641186 |
Gupta M et al.:
Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2
Blood
2009
14: 2926-2935
|
| 25070836 |
Rahmani M et al.:
PI3K/mTOR inhibition markedly potentiates HDAC inhibitor activity in NHL cells through BIM- and MCL-1-dependent mechanisms in vitro and in vivo
Clin. Cancer Res.
2014
20: 4849-4860
|
| 17588536 |
Sun GD et al.:
The endoplasmic reticulum stress-inducible protein Niban regulates eIF2alpha and S6K1/4E-BP1 phosphorylation
Biochem. Biophys. Res. Commun.
2007
360: 181-187
|
| 29717134 |
Wang Y et al.:
G3BP1 promotes tumor progression and metastasis through IL-6/G3BP1/STAT3 signaling axis in renal cell carcinomas
Cell Death Dis
2018
9: 501
|
| 30149063 |
Xiang P et al.:
Really interesting new gene finger protein 121 is a tumor suppressor of renal cell carcinoma
Gene
2018
676: 322-328
|
| 23143191 |
Clemen CS et al.:
Desminopathies: pathology and mechanisms
Acta Neuropathol.
2013
125: 47-75
|
| 11329061 |
Pashmforoush M et al.:
Adult mice deficient in actinin-associated LIM-domain protein reveal a developmental pathway for right ventricular cardiomyopathy
Nat. Med.
2001
7: 591-597
|
| 20373002 |
Ahmad S et al.:
Decreased myocardial expression of dystrophin and titin mRNA and protein in dilated cardiomyopathy: possibly an adverse effect of TNF-alpha
J. Clin. Immunol.
2010
30: 520-530
|
| 16951252 |
White DE et al.:
Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure
Genes Dev.
2006
20: 2355-2360
|
| 15541368 |
Minamisawa S et al.:
Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies
Biochem. Biophys. Res. Commun.
2004
325: 852-856
|
| 19652092 |
Liang X et al.:
Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality
Circulation
2009
120: 568-576
|
| 22905185 |
Frock RL et al.:
Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice
PLoS ONE
2012
7
|
| 25208486 |
Traister A et al.:
Integrin-linked kinase mediates force transduction in cardiomyocytes by modulating SERCA2a/PLN function
Nat Commun
2014
5: 4533
|
| 25226522 |
Ortega A et al.:
Endoplasmic reticulum stress induces different molecular structural alterations in human dilated and ischemic cardiomyopathy
PLoS ONE
2014
9
|
| 27807682 |
Papadopoulou-Legbelou K et al.:
Dilated Cardiomyopathy as the Only Clinical Manifestation of Carnitine Transporter Deficiency
Indian J Pediatr
2017
84: 231-233
|
| 24284026 |
Le CH et al.:
Delta-6-desaturase links polyunsaturated fatty acid metabolism with phospholipid remodeling and disease progression in heart failure
Circ Heart Fail
2014
7: 172-183
|
| 20930427 |
Ono H et al.:
A NADH dehydrogenase ubiquinone flavoprotein is decreased in patients with dilated cardiomyopathy
Intern. Med.
2010
49: 2039-2042
|
| 25778904 |
Watanabe K et al.:
Small interfering RNA therapy against carbohydrate sulfotransferase 15 inhibits cardiac remodeling in rats with dilated cardiomyopathy
Cell. Signal.
2015
27: 1517-1524
|
| 23360823 |
Baumgarten A et al. et al.:
TWIST1 regulates the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy
Int. J. Cardiol.
2013
168: 1447-1452
|
| 27693578 |
Yang N et al.:
The E3 ubiquitin ligase c-Cbl mediates integrin beta1 ubiquitination during dilated cardiomyopathy
Biochem. Biophys. Res. Commun.
2016
479: 728-735
|
| 21357822 |
Shende P et al.:
Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice
Circulation
2011
123: 1073-1082
|
| 27711126 |
Colak D et al.:
Integrated Left Ventricular Global Transcriptome and Proteome Profiling in Human End-Stage Dilated Cardiomyopathy
PLoS ONE
2016
11
|
| 25131203 |
Roh JI et al. et al.:
Perturbation of NCOA6 leads to dilated cardiomyopathy
Cell Rep
2014
8: 991-998
|
| 30339496 |
Oliveira AC et al. et al.:
Genetic deletion of the alamandine receptor MRGD leads to dilated cardiomyopathy in mice
Am. J. Physiol. Heart Circ. Physiol.
2019
316: H123-H133
|
| 26886563 |
Prestes PR et al.:
Tripartite motif-containing 55 identified as functional candidate for spontaneous cardiac hypertrophy in the rat locus cardiac mass 22
J. Hypertens.
2016
34: 950-958
|
| 24583314 |
Rafiq K et al. et al.:
c-Cbl inhibition improves cardiac function and survival in response to myocardial ischemia
Circulation
2014
129: 2031-2043
|
| 31268246 |
Guo J et al.:
A novel de novo CASZ1 heterozygous frameshift variant causes dilated cardiomyopathy and left ventricular noncompaction cardiomyopathy
|
| 28945738 |
Kennedy L et al.:
Formation of a TBX20-CASZ1 protein complex is protective against dilated cardiomyopathy and critical for cardiac homeostasis
PLoS Genet.
2017
13
|
| 30518548 |
Aspit L et al.:
CAP2 mutation leads to impaired actin dynamics and associates with supraventricular tachycardia and dilated cardiomyopathy
J. Med. Genet.
2019
56: 228-235
|
| 20031553 |
Fermin DR et al. et al.:
Sex and age dimorphism of myocardial gene expression in nonischemic human heart failure
Circ Cardiovasc Genet
2008
1: 117-125
|
| 23853074 |
Meder B et al. et al.:
A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy
Eur. Heart J.
2014
35: 1069-1077
|
| 28572699 |
Song H et al.:
Associations between Interleukin-31 Gene Polymorphisms and Dilated Cardiomyopathy in a Chinese Population
Dis. Markers
2017
2017
|
| 12379228 |
Daehmlow S et al.:
Novel mutations in sarcomeric protein genes in dilated cardiomyopathy
Biochem. Biophys. Res. Commun.
2002
298: 116-120
|
| 11784869 |
Zammit DJ et al.:
Essential role for the lymphostromal plasma membrane Ly-6 superfamily molecule thymic shared antigen 1 in development of the embryonic adrenal gland
Mol. Cell. Biol.
2002
22: 946-952
|
| 31071333 |
Ednie AR et al.:
Reduced hybrid/complex N-glycosylation disrupts cardiac electrical signaling and calcium handling in a model of dilated cardiomyopathy
J. Mol. Cell. Cardiol.
2019
132: 13-23
|
| 14662268 |
Vatta M et al. et al.:
Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction
J. Am. Coll. Cardiol.
2003
42: 2014-2027
|
| 19638707 |
Asakura M et al.:
Global gene expression profiling in the failing myocardium
Circ J
2009
73: 1568-1576
|
| 12591746 |
author information missing
article information missing
|
| 22119795 |
author information missing
article information missing
|
| 24315344 |
Peled Y et al.:
Titin mutation in familial restrictive cardiomyopathy
Int. J. Cardiol.
2014
171: 24-30
|
| 16376610 |
Arbustini E et al.:
Desmin accumulation restrictive cardiomyopathy and atrioventricular block associated with desmin gene defects
Eur. J. Heart Fail.
2006
8: 477-483
|
| 26472190 |
Teo LY et al.:
Evolving Approaches to Genetic Evaluation of Specific Cardiomyopathies
|
| 25813360 |
Zhang L et al.:
Calcium desensitizer catechin reverses diastolic dysfunction in mice with restrictive cardiomyopathy
Arch. Biochem. Biophys.
2015
573: 69-76
|
| 26666891 |
Brodehl A et al. et al.:
Mutations in FLNC are Associated with Familial Restrictive Cardiomyopathy
Hum. Mutat.
2016
37: 269-279
|
| 26163040 |
Wu W et al.:
Novel Phenotype-Genotype Correlations of Restrictive Cardiomyopathy With Myosin-Binding Protein C (MYBPC3) Gene Mutations Tested by Next-Generation Sequencing
|
| 25541130 |
Huby AC et al.:
Disturbance in Z-disk mechanosensitive proteins induced by a persistent mutant myopalladin causes familial restrictive cardiomyopathy
J. Am. Coll. Cardiol.
2014
64: 2765-2776
|
| 23906401 |
Yang SW et al.:
[Clinical characteristics and genetic analysis of three pediatric patients with idiopathic restrictive cardiomyopathy]
Zhonghua Xin Xue Guan Bing Za Zhi
2013
41: 304-309
|
| 8631348 |
Freiburg A et al.:
A molecular map of the interactions between titin and myosin-binding protein C. Implications for sarcomeric assembly in familial hypertrophic cardiomyopathy
Eur. J. Biochem.
1996
235: 317-323
|
| 19233194 |
Luckey SW et al.:
The role of Akt/GSK-3beta signaling in familial hypertrophic cardiomyopathy
J. Mol. Cell. Cardiol.
2009
46: 739-747
|
| 28630369 |
Caglayan AO et al. et al.:
ALPK3 gene mutation in a patient with congenital cardiomyopathy and dysmorphic features
|
| 26846950 |
Almomani R et al. et al.:
Biallelic Truncating Mutations in ALPK3 Cause Severe Pediatric Cardiomyopathy
J. Am. Coll. Cardiol.
2016
67: 515-525
|
| 31074094 |
Al Senaidi K et al.:
Phenotypic spectrum of ALPK3-related cardiomyopathy
Am. J. Med. Genet. A
2019
179: 1235-1240
|
| 21441111 |
Van Sligtenhorst I et al.:
Cardiomyopathy in alpha-kinase 3 (ALPK3)-deficient mice
Vet. Pathol.
2012
49: 131-141
|
| 25335496 |
Wessels MW et al.:
Compound heterozygous or homozygous truncating MYBPC3 mutations cause lethal cardiomyopathy with features of noncompaction and septal defects
Eur. J. Hum. Genet.
2015
23: 922-928
|
| 24327207 |
Lee YK et al.:
Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells
Pflugers Arch.
2014
466: 1831-1844
|
| 24819921 |
Greeley NR et al.:
Cross-sectional analysis of glucose metabolism in Friedreich ataxia
J. Neurol. Sci.
2014
342: 29-35
|
| 16263703 |
Schulz TJ et al.:
Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisited
J. Biol. Chem.
2006
281: 977-981
|
| 23280845 |
Cnop M et al.:
Central role and mechanisms of beta-cell dysfunction and death in friedreich ataxia-associated diabetes
Ann. Neurol.
2012
72: 971-982
|
| 11175786 |
Puccio H et al.:
Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits
Nat. Genet.
2001
27: 181-186
|
| 10899450 |
Vorgerd M et al.:
Mitochondrial impairment of human muscle in Friedreich ataxia in vivo
Neuromuscul. Disord.
2000
10: 430-435
|
| 19376812 |
Coppola G et al.:
Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreichs ataxia
Hum. Mol. Genet.
2009
18: 2452-2461
|
| 12925693 |
Ristow M et al.:
Frataxin deficiency in pancreatic islets causes diabetes due to loss of beta cell mass
J. Clin. Invest.
2003
112: 527-534
|
| 11986241 |
Becker EM et al.:
Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization
Blood
2002
99: 3813-3822
|
| 23552101 |
Bayot A et al.:
Cis-silencing of PIP5K1B evidenced in Friedreichs ataxia patient cells results in cytoskeleton anomalies
Hum. Mol. Genet.
2013
22: 2894-2904
|
| 20975743 |
Chou JY et al.:
Glycogen storage disease type I and G6Pase-beta deficiency: etiology and therapy
Nat Rev Endocrinol
2010
6: 676-688
|
| 25064003 |
Kuzaj P et al.:
ABCC6- a new player in cellular cholesterol and lipoprotein metabolism? }, authors { names std { { name ml Kuzaj P }, { name ml Kuhn J }, { name ml Dabisch-Ruthe M }, { name ml Faust I }, { name ml Gotting C }, { name ml Knabbe C }, { name ml Hendig D, affil str Herz- und Diabeteszentrum NRW, Institut fur Laboratoriums- und Transfusionsmedizin, Universitatsklinik der Ruhr-Universitat Bochum, Georgstrasse 11, 32 545 Bad Oeynhausen, Germany. dhendig@hdz-nrw.de
Lipids Health Dis
2014
13: 118
|
| 25265166 |
Kuzaj P et al.:
Large-scaled metabolic profiling of human dermal fibroblasts derived from pseudoxanthoma elasticum patients and healthy controls
PLoS ONE
2014
9
|
| 23248644 |
Le Saux O et al.:
The molecular and physiological roles of ABCC6: more than meets the eye
Front Genet
2012
3: 289
|
| 16261549 |
Pasquali-Ronchetti I et al.:
Oxidative stress in fibroblasts from patients with pseudoxanthoma elasticum: possible role in the pathogenesis of clinical manifestations
J. Pathol.
2006
208: 54-61
|
| 22229486 |
Li Q et al.:
Cutaneous features of pseudoxanthoma elasticum in a patient with generalized arterial calcification of infancy due to a homozygous missense mutation in the ENPP1 gene
Br. J. Dermatol.
2012
166: 1107-1111
|
| 28585220 |
Nitschke Y et al.:
Inherited Arterial Calcification Syndromes: Etiologies and Treatment Concepts
Curr Osteoporos Rep
2017
15: 255-270
|
| 22606356 |
Koch AJ et al.:
Loss of emerin alters myogenic signaling and miRNA expression in mouse myogenic progenitors
PLoS ONE
2012
7
|
| 21391237 |
Liang WC et al.:
TMEM43 mutations in Emery-Dreifuss muscular dystrophy-related myopathy
Ann. Neurol.
2011
69: 1005-1013
|
| 15671068 |
Zhang Q et al.:
Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle
J. Cell. Sci.
2005
118: 673-687
|
| 22103509 |
Meinke P et al.:
The LINC complex and human disease
Biochem. Soc. Trans.
2011
39: 1693-1697
|
| 11823453 |
Vatta M et al.:
Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome
Hum. Mol. Genet.
2002
11: 337-345
|
| 23414114 |
Risgaard B et al.:
High prevalence of genetic variants previously associated with Brugada syndrome in new exome data
Clin. Genet.
2013
84: 489-495
|
| 27707468 |
Zhang L et al.:
Does Sudden Unexplained Nocturnal Death Syndrome Remain the Autopsy-Negative Disorder: A Gross, Microscopic, and Molecular Autopsy Investigation in Southern China
|
| 31114854 |
Belbachir N et al. et al.:
RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome
Eur. Heart J.
2019
40: 3081-3094
|
| 17224476 |
Antzelevitch C et al. et al.:
Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death
Circulation
2007
115: 442-449
|
| 30821013 |
Campuzano O et al. et al.:
Genetic interpretation and clinical translation of minor genes related to Brugada syndrome
Hum. Mutat.
2019
40: 749-764
|
| 23559163 |
Riuro H et al. et al.:
A missense mutation in the sodium channel beta2 subunit reveals SCN2B as a new candidate gene for Brugada syndrome
Hum. Mutat.
2013
34: 961-966
|
| 24932359 |
Brugada R et al.:
Brugada syndrome
Methodist Debakey Cardiovasc J
2014
10: 25-28
|
| 11238270 |
Ichida F et al.:
Novel gene mutations in patients with left ventricular noncompaction or Barth syndrome
Circulation
2001
103: 1256-1263
|
| 20809236 |
Lardizabal JA et al.:
The role of renin-angiotensin agents in altering the natural history of type 2 diabetes mellitus
Curr Cardiol Rep
2010
12: 464-471
|
| 22155456 |
Schou J et al.:
Genetic variation in ABCG1 and risk of myocardial infarction and ischemic heart disease
Arterioscler. Thromb. Vasc. Biol.
2012
32: 506-515
|
| 24213632 |
Erdmann J et al.:
Dysfunctional nitric oxide signalling increases risk of myocardial infarction
Nature
2013
504: 432-436
|
| 16391217 |
Schulman SP et al.:
L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial
JAMA
2006
295: 58-64
|
| 19800018 |
Beigi F et al.:
Cardiac nitric oxide synthase-1 localization within the cardiomyocyte is accompanied by the adaptor protein, CAPON
Nitric Oxide
2009
21: 226-233
|
| 15166093 |
Zhou S et al.:
Mechanisms of cardiac nerve sprouting after myocardial infarction in dogs
Circ. Res.
2004
95: 76-83
|
| 15601581 |
Dent MR et al.:
Expression of phospholipase D isozymes in scar and viable tissue in congestive heart failure due to myocardial infarction
J. Cell. Mol. Med.
2004
8: 526-536
|
| 24184252 |
Pfister O et al.:
FLT3 activation improves post-myocardial infarction remodeling involving a cytoprotective effect on cardiomyocytes
J. Am. Coll. Cardiol.
2014
63: 1011-1019
|
| 24558405 |
Ghosh R et al.:
Reduction of death rate due to acute myocardial infarction in subjects with cancers through systemic restoration of impaired nitric oxide
PLoS ONE
2014
9
|
| 19726439 |
Jung C et al.:
Arginase inhibition mediates cardioprotection during ischaemia-reperfusion
Cardiovasc. Res.
2010
85: 147-154
|
| 22860052 |
Gonon AT et al.:
Local arginase inhibition during early reperfusion mediates cardioprotection via increased nitric oxide production
PLoS ONE
2012
7
|
| 24736300 |
Yoshino S et al.:
Single nucleotide polymorphisms associated with abnormal coronary microvascular function
Coron. Artery Dis.
2014
25: 281-289
|
| 26888119 |
Takeda N et al.:
Circadian clock and the onset of cardiovascular events
Hypertens. Res.
2016
39: 383-390
|
| 18316400 |
Bertolucci C et al.:
Evidence for an overlapping role of CLOCK and NPAS2 transcription factors in liver circadian oscillators
Mol. Cell. Biol.
2008
9: 3070-3075
|
| 21317191 |
Takeda Y et al.:
Retinoic acid-related orphan receptor gamma directly regulates neuronal PAS domain protein 2 transcription in vivo
Nucleic Acids Res.
2011
11: 4769-4782
|
| 17627769 |
Parsons SA et al.:
The Fps/Fes kinase regulates leucocyte recruitment and extravasation during inflammation
Immunology
2007
4: 542-550
|
| 19943878 |
Kondkar AA et al.:
VAMP8/endobrevin is overexpressed in hyperreactive human platelets: suggested role for platelet microRNA
J. Thromb. Haemost.
2010
8: 369-378
|
| 26725916 |
Gao Y et al.:
Bioinformatics Analyses of Differentially Expressed Genes Associated with Acute Myocardial Infarction
Cardiovasc Ther
2016
34: 67-75
|
| 16329997 |
Ria M et al.:
Human genetic evidence that OX40 is implicated in myocardial infarction
Biochem. Biophys. Res. Commun.
2006
339: 1001-1006
|
| 10198196 |
Hao J et al.:
Elevation of expression of Smads 2, 3, and 4, decorin and TGF-beta in the chronic phase of myocardial infarct scar healing
J. Mol. Cell. Cardiol.
1999
31: 667-678
|
| 17918316 |
Fischer P et al.:
Survival pathways in hypertrophy and heart failure: the gp130-STAT axis
Basic Res. Cardiol.
2007
102: 393-411
|
| 24155330 |
author information missing
article information missing
|
| 20686566 |
author information missing
article information missing
|
| 20686566 |
Musunuru K et al.:
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
Nature
2010
7307: 714-719
|
| 21427121 |
author information missing
article information missing
|
| 19198609 |
Kathiresan S et al.:
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
Nat. Genet.
2009
41: 334-341
|
| 25583993 |
et al.:
DNA methylation of lipid-related genes affects blood lipid levels
Circ Cardiovasc Genet
2015
8: 334-342
|
| 9888878 |
Serebruany VL et al.:
Effect of thrombolytic therapy on platelet expression and plasma concentration of PECAM-1 (CD31) in patients with acute myocardial infarction
Arterioscler. Thromb. Vasc. Biol.
1999
19: 153-158
|
| 25421410 |
Li AY et al.:
miR-133a mediates the hypoxia-induced apoptosis by inhibiting TAGLN2 expression in cardiac myocytes
Mol. Cell. Biochem.
2015
400: 173-181
|
| 25958931 |
Pereg D et al.:
Incidence and Expression of Circulating Cell Free p53-Related Genes in Acute Myocardial Infarction Patients
J. Atheroscler. Thromb.
2015
22: 981-998
|
| 25201905 |
Dodd MS et al.:
Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy
Circ Cardiovasc Imaging
2014
7: 895-904
|
| 24321516 |
Liu YT et al.:
Metabolic pathways involved in Xin-Ke-Shu protecting against myocardial infarction in rats using ultra high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry
J Pharm Biomed Anal
2014
90: 35-44
|
| 26146616 |
Zhang X et al.:
OSM Enhances Angiogenesis and Improves Cardiac Function after Myocardial Infarction
Biomed Res Int
2015
2015
|
| 24561551 |
Dai W et al.:
The roles of a novel anti-inflammatory factor, milk fat globule-epidermal growth factor 8, in patients with coronary atherosclerotic heart disease
Atherosclerosis
2014
233: 661-665
|
| 28499868 |
Li X et al.:
Exposure to particulate matter induces cardiomyocytes apoptosis after myocardial infarction through NFkappaB activation
Biochem. Biophys. Res. Commun.
2017
488: 224-231
|
| 19478464 |
Suzuki H et al.:
Serum hepcidin-20 is elevated during the acute phase of myocardial infarction
Tohoku J. Exp. Med.
2009
218: 93-98
|
| 10613625 |
Leng GC et al.:
Essential fatty acids and cardiovascular disease: the Edinburgh Artery Study
Vasc Med
1999
4: 219-226
|
| 11851861 |
Yli-Jama P et al.:
Serum free fatty acid pattern and risk of myocardial infarction: a case-control study
J. Intern. Med.
2002
251: 19-28
|
| 10951510 |
Pedersen JI et al.:
Adipose tissue fatty acids and risk of myocardial infarction--a case-control study
Eur J Clin Nutr
2000
54: 618-625
|
| 21195082 |
Cilenti L et al.:
Regulation of Abro1/KIAA0157 during myocardial infarction and cell death reveals a novel cardioprotective mechanism for Lys63-specific deubiquitination
J. Mol. Cell. Cardiol.
2011
50: 652-661
|
| 29991775 |
Yang L et al.:
MicroRNA-21 prevents excessive inflammation and cardiac dysfunction after myocardial infarction through targeting KBTBD7
Cell Death Dis
2018
9: 769
|
| 21771878 |
Port JD et al.:
Temporal expression of miRNAs and mRNAs in a mouse model of myocardial infarction
Physiol Genomics
2011
43: 1087-1095
|
| 27228353 |
Hall AR et al.:
Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction
Cell Death Dis
2016
7: e2238
|
| 29049183 |
Cheng M et al.:
Identifying key genes associated with acute myocardial infarction
Medicine (Baltimore)
2017
96: e7741
|
| 29232411 |
Stujanna EN et al. et al.:
Rev-erb agonist improves adverse cardiac remodeling and survival in myocardial infarction through an anti-inflammatory mechanism
PLoS ONE
2017
12
|
| 29016706 |
Bayoumi AS et al.:
MicroRNA-532 protects the heart in acute myocardial infarction, and represses prss23, a positive regulator of endothelial-to-mesenchymal transition
Cardiovasc Res
2017
113: 1603-1614
|
| 29395098 |
Wongsurawat T et al.:
Distinctive molecular signature and activated signaling pathways in aortic smooth muscle cells of patients with myocardial infarction
Atherosclerosis
2018
271: 237-244
|
| 31207208 |
Hu J et al.:
MicroRNA-155 inhibition attenuates endoplasmic reticulum stress-induced cardiomyocyte apoptosis following myocardial infarction via reducing macrophage inflammation
Eur. J. Pharmacol.
2019
857
|
| 31269974 |
Qiu L et al.:
Identification of key genes involved in myocardial infarction
Eur. J. Med. Res.
2019
24: 22
|
| 31269974 |
Qiu L et al.:
Identification of key genes involved in myocardial infarction
Eur J Med Res
2019
24: 22
|
| 29643704 |
Wang Y et al.:
Bioinformatic Analysis of the Possible Regulative Network of miR-30a/e in Cardiomyocytes 2 Days Post Myocardial Infarction
Acta Cardiol Sin
2018
34: 175-188
|
| 29775430 |
Derda AA et al.:
Gene expression profile analysis of aortic vascular smooth muscle cells reveals upregulation of cadherin genes in myocardial infarction patients
Physiol. Genomics
2018
50: 648-657
|
| 24915237 |
Levinsson A et al.:
Interaction effects of long-term air pollution exposure and variants in the GSTP1, GSTT1 and GSTCD genes on risk of acute myocardial infarction and hypertension: a case-control study
PLoS ONE
2014
9
|
| 27283840 |
Sanders LN et al.:
BMP Antagonist Gremlin 2 Limits Inflammation After Myocardial Infarction
Circ. Res.
2016
119: 434-449
|
| 29876469 |
Wongsurawat T et al.:
Transcriptome alterations of vascular smooth muscle cells in aortic wall of myocardial infarction patients
Data Brief
2018
17: 1112-1135
|
| 28931551 |
Reboll MR et al. et al.:
EMC10 (Endoplasmic Reticulum Membrane Protein Complex Subunit 10) Is a Bone Marrow-Derived Angiogenic Growth Factor Promoting Tissue Repair After Myocardial Infarction
Circulation
2017
136: 1809-1823
|
| 8086869 |
Kramer J et al.:
C4B*Q0 allotype as risk factor for myocardial infarction
BMJ
1994
309: 313-314
|
| 20035027 |
Rose JB et al.:
Equilibrative nucleoside transporter 1 plays an essential role in cardioprotection
Am. J. Physiol. Heart Circ. Physiol.
2010
298: H771-H777
|
| 31258652 |
Zhao X et al.:
Plasma-derived exosomal miR-183 associates with protein kinase activity and may serve as a novel predictive biomarker of myocardial ischemic injury
Exp Ther Med
2019
18: 179-187
|
| 19798445 |
author information missing
article information missing
|
| 30837465 |
author information missing
article information missing
|
| 36613626 |
author information missing
article information missing
|
| 15034580 |
Bienengraeber M et al. et al.:
ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating
Nat. Genet.
2004
36: 382-387
|
| 12684057 |
Chandrasekar B et al.:
TNF-alpha and H2O2 induce IL-18 and IL-18R beta expression in cardiomyocytes via NF-kappa B activation.
Biochem. Biophys. Res. Commun.
2003
303: 1152-1158
|
| 11742806 |
Sala R et al.:
Two-way arginine transport in human endothelial cells: TNF-alpha stimulation is restricted to system y(+)
Am. J. Physiol.
2002
282: C134-C143
|
| 20869944 |
Cortes VF et al.:
Regulatory phosphorylation of FXYD2 by PKC and cross interactions between FXYD2, plasmalemmal Ca-ATPase and Na,K-ATPase
Arch. Biochem. Biophys.
2011
505: 75-82
|
| 23785175 |
Obradovic M et al.:
Effects of obesity and estradiol on Na+/K+-ATPase and their relevance to cardiovascular diseases
J. Endocrinol.
2013
218: R13-R23
|
| 20064394 |
Lu Y et al.:
The ion channel ASIC2 is required for baroreceptor and autonomic control of the circulation
Neuron
2009
64: 885-897
|
| 18156197 |
Bray MS et al.:
Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression
Am. J. Physiol. Heart Circ. Physiol.
2008
294
|
| 22949532 |
Bannister JP et al.:
Transcriptional upregulation of alpha2delta-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension
Hypertension
2012
60: 1006-1015
|
| 21383000 |
Templin C et al.:
Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6)
Eur. Heart J.
2011
32: 1077-1088
|
| 19584346 |
Vasan RS et al.:
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data
JAMA
2009
302: 168-178
|
| 8099908 |
Tang S et al.:
Molecular localization of ion selectivity sites within the pore of a human L-type cardiac calcium channel
J. Biol. Chem.
1993
268
|
| 11309420 |
Bang ML et al.:
Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies
J. Cell Biol.
2001
153: 413-427
|
| 12840750 |
Takeda S et al.:
Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form
Nature
2003
424: 35-41
|
| 10987068 |
Sanger JW et al.:
Assembly of myofibrils in cardiac muscle cells
Adv. Exp. Med. Biol.
2000
481: 89-102
|
| 25217174 |
Lodder EM et al.:
An Integrative Genomic Approach Identifies Multiple Genes Involved in Cardiac Collagen Deposition
|
| 12358155 |
Jiang LQ et al.:
Screening the proteins that interact with calpain in a human heart cDNA library using a yeast two-hybrid system
Hypertens. Res.
2002
25: 647-652
|
| 12202917 |
Brown LJ et al.:
Functional and spectroscopic studies of a familial hypertrophic cardiomyopathy mutation in Motif X of cardiac myosin binding protein-C
Eur. Biophys. J.
2002
31: 400-408
|
| 14676215 |
Bullard B et al.:
Association of the chaperone alphaB-crystallin with titin in heart muscle
J. Biol. Chem.
2004
279: 7917-7924
|
| 11997265 |
Sadeghi A et al.:
Regulation of the cardiac L-type Ca2+ channel by the actin-binding proteins alpha-actinin and dystrophin
Am. J. Physiol.
2002
282
|
| 19850579 |
Mearini G et al.:
Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms
Cardiovasc. Res.
2010
85: 357-366
|
| 11927605 |
McElhinny AS et al.:
Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1
J. Cell Biol.
2002
157: 125-136
|
| 18782775 |
Cunha SR et al.:
Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line
J. Biol. Chem.
2008
283
|
| 18849322 |
Krishnan J et al.:
Essential role of developmentally activated hypoxia-inducible factor 1alpha for cardiac morphogenesis and function
Circ. Res.
2008
103: 1139-1146
|
| 16407297 |
McGrath MJ et al.:
Four and a half LIM protein 1 binds myosin-binding protein C and regulates myosin filament formation and sarcomere assembly
J. Biol. Chem.
2006
281: 7666-7683
|
| 19679835 |
Granzier HL et al.:
Truncation of titins elastic PEVK region leads to cardiomyopathy with diastolic dysfunction
Circ. Res.
2009
105: 557-564
|
| 23487791 |
Nam YJ et al.:
Reprogramming of human fibroblasts toward a cardiac fate
Proc. Natl. Acad. Sci. U.S.A.
2013
110: 5588-5593
|
| 10830164 |
Marx SO et al.:
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts
Cell
2000
101: 365-376
|
| 23040497 |
Nyegaard M et al.:
Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death
Am. J. Hum. Genet.
2012
91: 703-712
|
| 11178895 |
Amodeo P et al.:
Kinase recognition by calmodulin: modeling the interaction with the autoinhibitory region of human cardiac titin kinase
J. Mol. Biol.
2001
306: 81-95
|
| 22522929 |
Qian L et al.:
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes
Nature
2012
485: 593-598
|
| 23996002 |
Lin C et al. et al.:
Cypher/ZASP is a novel A-kinase anchoring protein
J. Biol. Chem.
2013
288
|
| 17189427 |
Laustsen PG et al.:
Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function
Mol. Cell. Biol.
2007
27: 1649-1664
|
| 17060380 |
Vatta M et al.:
Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome
Circulation
2006
114: 2104-2112
|
| 22879586 |
Guo J et al.:
Cell surface expression of human ether-a-go-go-related gene (hERG) channels is regulated by caveolin-3 protein via the ubiquitin ligase Nedd4-2
J. Biol. Chem.
2012
287
|
| 2584239 |
Noland TA Jr et al.:
Identification of sites phosphorylated in bovine cardiac troponin I and troponin T by protein kinase C and comparative substrate activity of synthetic peptides containing the phosphorylation sites
J. Biol. Chem.
1989
264
|
| 9346285 |
Keane NE et al.:
The ordered phosphorylation of cardiac troponin I by the cAMP-dependent protein kinase--structural consequences and functional implications
Eur. J. Biochem.
1997
248: 329-337
|
| 11101505 |
Tinel N et al.:
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
EMBO J.
2000
19: 6326-6330
|
| 9230439 |
McDonald TV et al.:
A minK-HERG complex regulates the cardiac potassium current I(Kr)
Nature
1997
388: 289-292
|
| 17592081 |
Medeiros-Domingo A et al.:
SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome
Circulation
2007
116: 134-142
|
| 18184654 |
Wu L et al.:
Identification of a new co-factor, MOG1, required for the full function of cardiac sodium channel Nav 1.5
J. Biol. Chem.
2008
283: 6968-6978
|
| 21257757 |
Frank D et al.:
Cardiac Z-disc signaling network
J. Biol. Chem.
2011
286: 9897-9904
|
| 24202214 |
Suzuki Y et al.:
Caveolin-1 facilitates the direct coupling between large conductance Ca2+-activated K+ (BKCa) and Cav1.2 Ca2+ channels and their clustering to regulate membrane excitability in vascular myocytes
J. Biol. Chem.
2013
288
|
| 10567342 |
Bunemann M et al.:
Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the beta(2) subunit
J. Biol. Chem.
1999
274
|
| 23311301 |
Bosman A et al.:
Molecular and functional evidence of HCN4 and caveolin-3 interaction during cardiomyocyte differentiation from human embryonic stem cells
Stem Cells Dev.
2013
22: 1717-1727
|
| 24375547 |
Du Y et al.:
Lentiviral-mediated overexpression of Akt1 reduces anoxia-reoxygenation injury in cardiomyocytes
Cell Biol. Int.
2014
38: 488-496
|
| 12039794 |
Hardt SE et al.:
Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development
Circ. Res.
2002
90: 1055-1063
|
| 25888601 |
Cieslik KA et al.:
Mesenchymal stem cell-derived inflammatory fibroblasts promote monocyte transition into myeloid fibroblasts via an IL-6-dependent mechanism in the aging mouse heart
FASEB J.
2015
29: 3160-3170
|
| 17242280 |
Oceandy D et al.:
Neuronal nitric oxide synthase signaling in the heart is regulated by the sarcolemmal calcium pump 4b
Circulation
2007
115: 483-492
|
| 26141232 |
author information missing
article information missing
|
| 1721623 |
author information missing
article information missing
|
| 9538934 |
author information missing
article information missing
|
| 11175743 |
author information missing
article information missing
|
| 18272434 |
Weisleder N et al.:
Altered Ca2+ sparks in aging skeletal and cardiac muscle
Ageing Res. Rev.
2008
7: 177-188
|
| 23991041 |
Cheng F et al.:
Impact of glutathione peroxidase-1 deficiency on macrophage foam cell formation and proliferation: implications for atherogenesis
PLoS ONE
2013
8
|
| 17374715 |
Lu G et al.:
A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development
Genes Dev.
2007
21: 784-796
|
| 9609086 |
Lapenna D et al.:
Glutathione-related antioxidant defenses in human atherosclerotic plaques
Circulation
1998
97: 1930-1934
|
| 17420349 |
Sharma A et al.:
Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium
Vascul. Pharmacol.
2016
79: 32-42
|
| 26395740 |
Berglund LM et al.:
Glucose-Dependent Insulinotropic Polypeptide Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB
Diabetes
2016
1: 239-254
|
| 26395740 |
Berglund LM et al.:
Glucose-Dependent Insulinotropic Polypeptide Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB
Diabetes
2016
65: 239-254
|
| 25189738 |
Khan S et al.:
ER stress in adipocytes and insulin resistance: mechanisms and significance (Review)
Mol Med Rep
2014
10: 2234-2240
|
| 11068947 |
Okatani Y et al.:
Melatonin suppresses lysophosphatidylcholine enhancement of serotonin-induced vasoconstriction in the human umbilical artery
J. Pineal Res.
2000
29: 241-247
|
| 26773361 |
Baghaei A et al.:
Molecular and biochemical evidence on the protection of cardiomyocytes from phosphine-induced oxidative stress, mitochondrial dysfunction and apoptosis by acetyl-L-carnitine
Environ. Toxicol. Pharmacol.
2016
42: 30-37
|
| 22238215 |
Schroeder MA et al.:
The cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study
Circ Cardiovasc Imaging
2012
5: 201-209
|
| 26996423 |
Leem J et al.:
Mechanisms of Vascular Calcification: The Pivotal Role of Pyruvate Dehydrogenase Kinase 4
Endocrinol Metab (Seoul)
2016
1: 52-61
|
| 15550462 |
Sharma N et al.:
Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation
J. Physiol. (Lond.)
2005
562: 593-603
|
| 28655204 |
Lake NJ et al.:
TRAK2, a novel regulator of ABCA1 expression, cholesterol efflux and HDL biogenesis
|
| 24175071 |
Wong HK et al.:
Adrenomedullin and cardiovascular diseases
|
| 15498818 |
Brueggemann LI et al.:
Low voltage-activated calcium channels in vascular smooth muscle: T-type channels and AVP-stimulated calcium spiking
Am. J. Physiol. Heart Circ. Physiol.
2005
288: H923-H935
|
| 25826393 |
Song HK et al.:
Pik3ip1 modulates cardiac hypertrophy by inhibiting PI3K pathway
PLoS ONE
2015
10
|
| 19184368 |
Cheng YC et al.:
ZAK induces MMP-2 activity via JNK/p38 signals and reduces MMP-9 activity by increasing TIMP-1/2 expression in H9c2 cardiomyoblast cells
Mol. Cell. Biochem.
2009
325: 69-77
|
| 22901457 |
Brkic L et al.:
Acyl chain-dependent effect of lysophosphatidylcholine on cyclooxygenase (COX)-2 expression in endothelial cells
Atherosclerosis
2012
224: 348-354
|
| 28576971 |
Willer MK et al.:
Substrate stiffness-dependent regulation of the SRF-Mkl1 co-activator complex requires the inner nuclear membrane protein Emerin
J. Cell. Sci.
2017
130: 2111-2118
|
| 27890711 |
Al Suleimani YM et al.:
The endogenous lipid N-arachidonoyl glycine is hypotensive and nitric oxide-cGMP-dependent vasorelaxant
Eur. J. Pharmacol.
2017
794: 209-215
|
| 11893587 |
Ray J et al.:
Long-chain fatty acids increase basal metabolism and depolarize mitochondria in cardiac muscle cells
Am. J. Physiol. Heart Circ. Physiol.
2002
282
|
| 8135845 |
Tassani V et al.:
Anaplerotic effect of propionyl carnitine in rat heart mitochondria
Biochem. Biophys. Res. Commun.
1994
199: 949-953
|
| 1625347 |
Ferrari R et al.:
Prolonged propionyl-L-carnitine pre-treatment of rabbit: biochemical, hemodynamic and electrophysiological effects on myocardium
J. Mol. Cell. Cardiol.
1992
24: 219-232
|
| 15591005 |
Ferrari R et al.:
Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review
Ann. N. Y. Acad. Sci.
2004
1033: 79-91
|
| 24225147 |
Hu Z et al.:
Kcne3 deletion initiates extracardiac arrhythmogenesis in mice
FASEB J.
2014
28: 935-945
|
| 30142973 |
Bier A et al.:
A High Salt Diet Modulates the Gut Microbiota and Short Chain Fatty Acids Production in a Salt-Sensitive Hypertension Rat Model
|
| 27845446 |
Cohn O et al.:
Chromatin associated SETD3 negatively regulates VEGF expression
Sci Rep
2016
6: 37115
|
| 14672936 |
Tsunematsu R et al.:
Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development
J. Biol. Chem.
2004
279: 9417-9423
|
| 27924221 |
Liu L et al.:
Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts
Cell Discov
2016
2: 16036
|
| 30054797 |
Parsons RL et al.:
PACAP-Induced PAC1 Receptor Internalization and Recruitment of Endosomal Signaling Regulate Cardiac Neuron Excitability
|
| 15520307 |
Otto C et al.:
Pulmonary hypertension and right heart failure in pituitary adenylate cyclase-activating polypeptide type I receptor-deficient mice
Circulation
2004
110: 3245-3251
|
| 27768769 |
Fisher JB et al.:
Depletion of Tip60 from In Vivo Cardiomyocytes Increases Myocyte Density, Followed by Cardiac Dysfunction, Myocyte Fallout and Lethality
PLoS ONE
2016
11
|
| 22348108 |
Fisher JB et al.:
Stress-induced cell-cycle activation in Tip60 haploinsufficient adult cardiomyocytes
PLoS ONE
2012
7
|
| 29100060 |
Vilne B et al.:
Network analysis reveals a causal role of mitochondrial gene activity in atherosclerotic lesion formation
Atherosclerosis
2017
267: 39-48
|
| 19553562 |
Qu A et al.:
PGC-1alpha attenuates neointimal formation via inhibition of vascular smooth muscle cell migration in the injured rat carotid artery
Am. J. Physiol.
2009
297: C645-C653
|
| 20668027 |
Liang XH et al.:
Estrogen regulates amiloride-binding protein 1 through CCAAT/enhancer-binding protein-beta in mouse uterus during embryo implantation and decidualization
Endocrinology
2010
151: 5007-5016
|
| 27959335 |
Mercer KB et al.:
Functional evaluation of a PTSD-associated genetic variant: estradiol regulation and ADCYAP1R1
Transl Psychiatry
2016
6: e978
|
| 25168380 |
Wang P et al.:
The alteration of Hippo/YAP signaling in the development of hypertrophic cardiomyopathy
Basic Res. Cardiol.
2014
109: 435
|
| 30661960 |
Fibbe WE et al.:
FOXO3, a Molecular Search for the Fountain of Youth
Cell Stem Cell
2019
24: 351-352
|
| 29111822 |
Peliciari-Garcia RA et al.:
Repercussions of hypo and hyperthyroidism on the heart circadian clock
Chronobiol. Int.
2018
35: 147-159
|
| 30221680 |
Zhu H et al.:
Hyperosmotic stress stimulates autophagy via the NFAT5/mTOR pathway in cardiomyocytes
Int. J. Mol. Med.
2018
42: 3459-3466
|
| 19423552 |
Joe B et al. et al.:
Positional identification of variants of Adamts16 linked to inherited hypertension
Hum. Mol. Genet.
2009
18: 2825-2838
|
| 21569246 |
Uys GM et al.:
Myomegalin is a novel A-kinase anchoring protein involved in the phosphorylation of cardiac myosin binding protein C
BMC Cell Biol.
2011
12: 18
|
| 7744002 |
Gautel M et al.:
Phosphorylation switches specific for the cardiac isoform of myosin binding protein-C: a modulator of cardiac contraction?
EMBO J.
1995
14: 1952-1960
|
| 17923693 |
Faul C et al.:
Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes
Mol Cell Biol
2007
27: 8215-8227
|
| 27501845 |
Moore JB 4th et al.:
The Epigenetic Regulator HDAC1 Modulates Transcription of a Core Cardiogenic Program in Human Cardiac Mesenchymal Stromal Cells Through a p53-Dependent Mechanism
Stem Cells
2016
34: 2916-2929
|
| 24690943 |
Lu DF et al.:
Downregulation of HDAC1 is involved in the cardiomyocyte differentiation from mesenchymal stem cells in a myocardial microenvironment
PLoS ONE
2014
9
|
| 22617702 |
Liu XH et al.:
Metabotropic glutamate subtype 7 and 8 receptors oppositely modulate cardiac nociception in the rat nucleus tractus solitarius
Neuroscience
2012
220: 322-329
|
| 16452489 |
Mao C et al.:
In vivo regulation of Grp78/BiP transcription in the embryonic heart: role of the endoplasmic reticulum stress response element and GATA-4
J. Biol. Chem.
2006
281: 8877-8887
|
| 10645959 |
Nakajima Y et al.:
Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP)
Anat. Rec.
2000
258: 119-127
|
| 21037199 |
Auerbach SS et al.:
Comparative phenotypic assessment of cardiac pathology, physiology, and gene expression in C3H/HeJ, C57BL/6J, and B6C3F1/J mice
Toxicol Pathol
2010
38: 923-942
|
| 15665098 |
Serneels L et al. et al.:
Differential contribution of the three Aph1 genes to gamma-secretase activity in vivo
Proc. Natl. Acad. Sci. U.S.A.
2005
102: 1719-1724
|
| 20031625 |
Bosse Y et al.:
Refining molecular pathways leading to calcific aortic valve stenosis by studying gene expression profile of normal and calcified stenotic human aortic valves
Circ Cardiovasc Genet
2009
2: 489-498
|
| 28827564 |
Bielecka-Dabrowa A et al.:
The profile of selected single nucleotide polymorphisms in patients with hypertension and heart failure with preserved and mid-range ejection fraction
Sci Rep
2017
7: 8974
|
| 29891665 |
Wilczewski CM et al.:
CHD4 and the NuRD complex directly control cardiac sarcomere formation
Proc Natl Acad Sci U S A
2018
115: 6727-6732
|
| 22932696 |
Vijayaraj P et al.:
Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis
Development
2012
139: 3973-3985
|
| 27528004 |
Ang R et al.:
The role of GalphaO-mediated signaling in the rostral ventrolateral medulla oblongata in cardiovascular reflexes and control of cardiac ventricular excitability
|
| 15194465 |
Stawowy P et al.:
Regulation of matrix metalloproteinase MT1-MMP/MMP-2 in cardiac fibroblasts by TGF-beta1 involves furin-convertase
Cardiovasc Res
2004
63: 87-97
|
| 21454626 |
Liu H et al.:
Functional redundancy between human SHOX and mouse Shox2 genes in the regulation of sinoatrial node formation and pacemaking function
J Biol Chem
2011
286
|
| 23744058 |
Zheng W et al. et al.:
SIRT1 mediates the protective function of Nkx2.5 during stress in cardiomyocytes
Basic Res Cardiol
2013
108: 364
|
| 11106640 |
Guo L et al.:
COUP-TF1 antagonizes Nkx2.5-mediated activation of the calreticulin gene during cardiac development
J. Biol. Chem.
2001
276: 2797-2801
|
| 24633547 |
Komatsu S et al.:
ZIPK is critical for the motility and contractility of VSMCs through the regulation of nonmuscle myosin II isoforms
Am J Physiol Heart Circ Physiol
2014
306
|
| 31297131 |
Kiselev A et al. et al.:
Truncating Variant in Myof Gene Is Associated With Limb-Girdle Type Muscular Dystrophy and Cardiomyopathy
Front Genet
2019
10: 608
|
| 20184720 |
McNeill EM et al.:
Nav2 is necessary for cranial nerve development and blood pressure regulation
Neural Dev
2010
5: 6
|
| 26778110 |
Watari K et al.:
Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice
Sci Rep
2016
6: 19470
|
| 21757659 |
Halterman JA et al.:
Nuclear factor of activated T cells 5 regulates vascular smooth muscle cell phenotypic modulation
Arterioscler. Thromb. Vasc. Biol.
2011
31: 2287-2296
|
| 31429763 |
Ma P et al.:
NFAT5 mediates hypertonic stress-induced atherosclerosis via activating NLRP3 inflammasome in endothelium
Cell Commun. Signal
2019
17: 102
|
| 27368804 |
Li W et al. et al.:
NFAT5-mediated CACNA1C expression is critical for cardiac electrophysiological development and maturation
J. Mol. Med.
2016
94: 993-1002
|
| 27899146 |
Obata Y et al. et al.:
Impact of visceral fat on gene expression profile in peripheral blood cells in obese Japanese subjects
Cardiovasc Diabetol
2016
15: 159
|
| 20955564 |
Ma W et al.:
Interaction of functional NPC1 gene polymorphism with smoking on coronary heart disease
BMC Med. Genet.
2010
11: 149
|
| 30611994 |
Liu X et al.:
Paeoniflorin improves pressure overload-induced cardiac remodeling by modulating the MAPK signaling pathway in spontaneously hypertensive rats
Biomed. Pharmacother.
2019
111: 695-704
|
| 30506890 |
Guan Y et al. et al.:
Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity
J. Cell. Mol. Med.
2019
23: 1448-1457
|
| 29191809 |
Gabel G et al.:
Molecular Fingerprint for Terminal Abdominal Aortic Aneurysm Disease
|
| 10551266 |
Zhu XR et al.:
Structural and functional characterization of Kv6.2 a new gamma-subunit of voltage-gated potassium channel
Recept. Channels
1999
6: 337-350
|
| 26616005 |
Field J et al.:
CAP2 in cardiac conduction, sudden cardiac death and eye development
Sci Rep
2015
5: 17256
|
| 17376817 |
Niessen K et al.:
Notch signaling in the developing cardiovascular system
Am. J. Physiol.
2007
293: C1-11
|
| 31080136 |
Hashimoto H et al. et al.:
Cardiac Reprogramming Factors Synergistically Activate Genome-wide Cardiogenic Stage-Specific Enhancers
Cell Stem Cell
2019
25: 69-86.e5
|
| 26519030 |
Kuo MM et al.:
MPST but not CSE is the primary regulator of hydrogen sulfide production and function in the coronary artery
Am. J. Physiol. Heart Circ. Physiol.
2016
310: H71-H79
|
| 26375510 |
Wang W et al. et al.:
Comparative transcriptome analysis of atrial septal defect identifies dysregulated genes during heart septum morphogenesis
Gene
2016
575: 303-312
|
| 23879989 |
Voigt C et al. et al.:
Oto-facial syndrome and esophageal atresia, intellectual disability and zygomatic anomalies - expanding the phenotypes associated with EFTUD2 mutations
Orphanet J Rare Dis
2013
8: 110
|
| 31235857 |
Colijn S et al.:
The NuRD chromatin-remodeling complex enzyme CHD4 prevents hypoxia-induced endothelial Ripk3 transcription and murine embryonic vascular rupture
Cell Death Differ
2020
27: 618-631
|
| 9804427 |
Tong JK et al.:
Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex
Nature
1998
395: 917-921
|
| 20618517 |
Sheu JJ et al.:
Association of COL11A2 polymorphism with susceptibility to Kawasaki disease and development of coronary artery lesions
Int. J. Immunogenet.
2010
37: 487-492
|
| 29885250 |
Haugaard SF et al.:
The complement lectin pathway after cardiac arrest
|
| 28406175 |
Panzer AA et al.:
Nkx2-5 and Sarcospan genetically interact in the development of the muscular ventricular septum of the heart
Sci Rep
2017
7: 46438
|
| 22226977 |
Chakraborty S et al.:
Tbx20 regulation of cardiac cell proliferation and lineage specialization during embryonic and fetal development in vivo
Dev Biol
2012
363: 234-246
|
| 23526217 |
Li X et al.:
BMP4 increases canonical transient receptor potential protein expression by activating p38 MAPK and ERK1/2 signaling pathways in pulmonary arterial smooth muscle cells
Am J Respir Cell Mol Biol
2013
49: 212-220
|
| 18275040 |
Hammer S et al.:
Characterization of TBX20 in human hearts and its regulation by TFAP2
J Cell Biochem
2008
104: 1022-1033
|
| 25522363 |
Cagavi E et al.:
Functional cardiomyocytes derived from Isl1 cardiac progenitors via Bmp4 stimulation
PLoS One
2014
9
|
| 12755708 |
Nishimoto S et al.:
A novel homocysteine-responsive gene, smap8, modulates mitogenesis in rat vascular smooth muscle cells
Eur J Biochem
2003
270: 2521-2531
|
| 19932097 |
Steiner-Champliaud MF et al. et al.:
BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin
Exp Cell Res
2010
316: 297-313
|
| 30525268 |
Zhaolin Z et al.:
Role of pyroptosis in cardiovascular disease
Cell Prolif.
2019
52
|
| 29530068 |
Abu-Halima M et al.:
Deregulated microRNA and mRNA expression profiles in the peripheral blood of patients with Marfan syndrome
J Transl Med
2018
16: 60
|
| 27528761 |
Li W et al.:
Regulation of the ALK1 ligands, BMP9 and BMP10
Biochem. Soc. Trans.
2016
44: 1135-1141
|
| 9050846 |
Valenzuela D et al.:
G alpha(o) is necessary for muscarinic regulation of Ca2+ channels in mouse heart
Proc. Natl. Acad. Sci. U.S.A.
1997
94: 1727-1732
|
| 20950623 |
Hayashi K et al. et al.:
A KCR1 variant implicated in susceptibility to the long QT syndrome
J. Mol. Cell. Cardiol.
2011
50: 50-57
|
| 21542006 |
Zhang R et al.:
Unique roles of phosphorus in endochondral bone formation and osteocyte maturation
J. Bone Miner. Res.
2011
26: 1047-1056
|
| 31044094 |
Dussold C et al. et al.:
DMP1 prevents osteocyte alterations, FGF23 elevation and left ventricular hypertrophy in mice with chronic kidney disease
Bone Res
2019
7: 12
|
| 27390906 |
Yoon CY et al. et al.:
Low Dentin Matrix Protein 1 Is Associated With Incident Cardiovascular Events in Peritoneal Dialysis Patients
J. Bone Miner. Res.
2016
31: 2149-2158
|
| 28768233 |
author information missing
article information missing
|
| 31205684 |
Hashmi S et al.:
Molecular switch model for cardiomyocyte proliferation
Cell Regen (Lond)
2019
8: 12-20
|
| 23213106 |
Chen IH et al.:
PRSS23 is essential for the Snail-dependent endothelial-to-mesenchymal transition during valvulogenesis in zebrafish
Cardiovasc. Res.
2013
97: 443-453
|
| 27911441 |
Prola A et al. et al.:
SIRT1 protects the heart from ER stress-induced cell death through eIF2alpha deacetylation
Cell Death Differ.
2017
24: 343-356
|
| 22939634 |
Soemedi R et al. et al.:
Contribution of global rare copy-number variants to the risk of sporadic congenital heart disease
Am. J. Hum. Genet.
2012
91: 489-501
|
| 15306692 |
Chen H et al.:
Gene expression changes associated with fibronectin-induced cardiac myocyte hypertrophy
Physiol. Genomics
2004
18: 273-283
|
| 26297872 |
Briggs LE et al.:
Wnt/beta-catenin and sonic hedgehog pathways interact in the regulation of the development of the dorsal mesenchymal protrusion
Dev. Dyn.
2016
245: 103-113
|
| 14581414 |
Barandon L et al.:
Reduction of infarct size and prevention of cardiac rupture in transgenic mice overexpressing FrzA
Circulation
2003
108: 2282-2289
|
| 27768722 |
Melleby AO et al.:
The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling
PLoS ONE
2016
11
|
| 16820567 |
Cullen ME et al.:
Myocardial expression of the arginine:glycine amidinotransferase gene is elevated in heart failure and normalized after recovery: potential implications for local creatine synthesis
Circulation
2006
114: I16-I20
|
| 15789410 |
Vincentz JW et al.:
Fgf15 is required for proper morphogenesis of the mouse cardiac outflow tract
Genesis
2005
41: 192-201
|
| 21472842 |
Jung S et al.:
Developmental cardiac hypertrophy in a mouse model of prolidase deficiency
Birth Defects Res A Clin Mol Teratol
2011
91: 204-217
|
| 24425002 |
Varadkar P et al.:
The protein phosphatase 2A B56gamma regulatory subunit is required for heart development
Dev. Dyn.
2014
243: 778-790
|
| 23620086 |
Sun C et al.:
Generation of Shox2-Cre allele for tissue specific manipulation of genes in the developing heart, palate, and limb
Genesis
2013
51: 515-522
|
| 15070745 |
Liu W et al.:
Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodeling
Proc. Natl. Acad. Sci. U.S.A.
2004
101: 4489-4494
|
| 23455426 |
Hoffmann S et al.:
Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia
Basic Res. Cardiol.
2013
108: 339
|
| 22577142 |
Lee MJ et al.:
Characterization of arginylation branch of N-end rule pathway in G-protein-mediated proliferation and signaling of cardiomyocytes
J. Biol. Chem.
2012
287
|
| 29575631 |
Birgmeier J et al.:
Biallelic loss-of-function WNT5A mutations in an infant with severe and atypical manifestations of Robinow syndrome
Am. J. Med. Genet. A
2018
176: 1030-1036
|
| 15634781 |
Ma G et al.:
APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development
J. Neurosci.
2005
25: 192-198
|
| 16391491 |
Gorgojo JJ et al.:
A Spanish founder mutation in the chloride channel gene, CLCNKB, as a cause of atypical Bartter syndrome in adult age
Horm. Res.
2006
65: 62-68
|
| 24584636 |
Mandrile G et al.:
Cerebrotendinous xanthomatosis: recurrence of the CYP27A1 mutation p.Arg479Cys in Sardinia
Neurol. Sci.
2014
35: 1303-1305
|
| 17105751 |
Syrris P et al.:
Desmoglein-2 mutations in arrhythmogenic right ventricular cardiomyopathy: a genotype-phenotype characterization of familial disease
Eur. Heart J.
2007
28: 581-588
|
| 27604170 |
Ploski R et al.:
Evidence for troponin C (TNNC1) as a gene for autosomal recessive restrictive cardiomyopathy with fatal outcome in infancy
Am. J. Med. Genet. A
2016
170: 3241-3248
|
| 24485043 |
Catteruccia M et al. et al.:
Persistent pulmonary arterial hypertension in the newborn (PPHN): a frequent manifestation of TMEM70 defective patients
Mol. Genet. Metab.
2014
111: 353-359
|
| 26419279 |
Levitas A et al.:
D117N in Cypher/ZASP may not be a causative mutation for dilated cardiomyopathy and ventricular arrhythmias
Eur. J. Hum. Genet.
2016
24: 666-671
|
| 19966803 |
Cirstea IC et al. et al.:
A restricted spectrum of NRAS mutations causes Noonan syndrome
Nat. Genet.
2010
42: 27-29
|
| 16675849 |
Zhang YM et al.:
Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis
FASEB J.
2006
20: 916-925
|
| 19808477 |
Watanabe H et al.:
Mutations in sodium channel beta1- and beta2-subunits associated with atrial fibrillation
Circ Arrhythm Electrophysiol
2009
2: 268-275
|
| 24687295 |
Muhlhausen C et al.:
Combined D2-/L2-hydroxyglutaric aciduria (SLC25A1 deficiency): clinical course and effects of citrate treatment
J. Inherit. Metab. Dis.
2014
37: 775-781
|
| 32808564 |
Ding Y et al. et al.:
Knockout of SORBS2 Protein Disrupts the Structural Integrity of Intercalated Disc and Manifests Features of Arrhythmogenic Cardiomyopathy
J Am Heart Assoc
2020
9
|
| 7958896 |
Chen Z et al.:
Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice
Genes Dev.
1994
8: 2293-2301
|
| 24700782 |
van Breevoort D et al. et al.:
STXBP1 promotes Weibel-Palade body exocytosis through its interaction with the Rab27A effector Slp4-a
Blood
2014
123: 3185-3194
|
| 21472842 |
Jung S et al.:
Developmental cardiac hypertrophy in a mouse model of prolidase deficiency
Birth Defects Res. Part A Clin. Mol. Teratol.
2011
91: 204-217
|
| 29115576 |
Li D et al.:
Genome-wide DNA methylome alterations in acute coronary syndrome
Int. J. Mol. Med.
2018
41: 220-232
|
| 23223679 |
Muller II et al.:
Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm
Dis Model Mech
2013
6: 332-341
|
| 24648383 |
Tanwar V et al. et al.:
Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway
Stem Cells
2014
32: 1774-1788
|
| 6862443 |
author information missing
Confirmation of a de novo duplication, dup(10)(q24 leads to q26), by GOT1 gene dosage studies
Hum. Genet.
1983
63: 369-373
|
| 23874591 |
Ong WY et al.:
Comprehensive gene expression profiling reveals synergistic functional networks in cerebral vessels after hypertension or hypercholesterolemia
PLoS ONE
2013
8
|
| 24665114 |
Amin MA et al.:
A key role for Fut1-regulated angiogenesis and ICAM-1 expression in K/BxN arthritis
Ann. Rheum. Dis.
2015
74: 1459-1466
|
| 25852081 |
Haubner BJ et al.:
In vivo cardiac role of migfilin during experimental pressure overload
Cardiovasc. Res.
2015
106: 398-407
|
| 14757752 |
Akazawa H et al.:
A novel LIM protein Cal promotes cardiac differentiation by association with CSX/NKX2-5
J. Cell Biol.
2004
164: 395-405
|
| 26546165 |
Maejima Y et al.:
Regulation of autophagy by Beclin 1 in the heart
J. Mol. Cell. Cardiol.
2016
95: 19-25
|
| 19270745 |
Baskind HA et al.:
Functional conservation of Asxl2, a murine homolog for the Drosophila enhancer of trithorax and polycomb group gene Asx
PLoS ONE
2009
4: e4750
|
| 29615595 |
Brunner R et al.:
Asxl2(-/-) Mice Exhibit De Novo Cardiomyocyte Production during Adulthood
|
| 11719371 |
McLaughlin F et al.:
Combined genomic and antisense analysis reveals that the transcription factor Erg is implicated in endothelial cell differentiation
Blood
2001
98: 3332-3339
|
| 31676784 |
Peghaire C et al. et al.:
The transcription factor ERG regulates a low shear stress-induced anti-thrombotic pathway in the microvasculature
Nat Commun
2019
10: 5014
|
| 27208692 |
Shah AV et al.:
Regulation of endothelial homeostasis, vascular development and angiogenesis by the transcription factor ERG
Vascul. Pharmacol.
2016
86: 3-13
|
| 24247717 |
Venkateswaran A et al.:
The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development
Cancer Res.
2014
74: 38-43
|
| 29483644 |
Paulitti A et al. et al.:
The ablation of the matricellular protein EMILIN2 causes defective vascularization due to impaired EGFR-dependent IL-8 production affecting tumor growth
Oncogene
2018
37: 3399-3414
|
| 18678517 |
Posch MG et al. et al.:
A missense variant in desmoglein-2 predisposes to dilated cardiomyopathy
Mol. Genet. Metab.
2008
95: 74-80
|
| 27129184 |
Takahashi K et al.:
Dysregulation of ossification-related miRNAs in circulating osteogenic progenitor cells obtained from patients with aortic stenosis
Clin. Sci.
2016
130: 1115-1124
|
| 27479907 |
Sifrim A et al. et al.:
Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing
Nat. Genet.
2016
48: 1060-1065
|
| 26263970 |
Huber M et al.:
A Single Nucleotide Polymorphism near the CYP17A1 Gene Is Associated with Left Ventricular Mass in Hypertensive Patients under Pharmacotherapy
Int J Mol Sci
2015
16
|
| 16816023 |
author information missing
Total absence of the alpha2(I) chain of collagen type I causes a rare form of Ehlers-Danlos syndrome with hypermobility and propensity to cardiac valvular problems
J. Med. Genet.
2006
43: e36
|
| 20039031 |
Chakraborty S et al.:
Transcriptional regulation of heart valve progenitor cells
Pediatr Cardiol
2010
31: 414-421
|
| 26857067 |
Yan XC et al. et al.:
miR-342-5p Is a Notch Downstream Molecule and Regulates Multiple Angiogenic Pathways Including Notch, Vascular Endothelial Growth Factor and Transforming Growth Factor beta Signaling
|
| 30613277 |
Xie YP et al.:
CDC20 regulates cardiac hypertrophy via targeting LC3-dependent autophagy
Theranostics
2018
8: 5995-6007
|
| 21512031 |
Heallen T et al.:
Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size
Science
2011
332: 458-461
|
| 10811847 |
Passier R et al.:
CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo
J. Clin. Invest.
2000
105: 1395-1406
|
| 24141421 |
Maejima Y et al. et al.:
Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2
Nat. Med.
2013
19: 1478-1488
|
| 12489796 |
Spillmann F et al.:
Regulation of cardiac bradykinin B1- and B2-receptor mRNA in experimental ischemic, diabetic, and pressure-overload-induced cardiomyopathy
Int. Immunopharmacol.
2002
2: 1823-1832
|
| 11093075 |
Hayashi Y et al.:
Cardioprotective effects of MET-88, a gamma-butyrobetaine hydroxylase inhibitor, on cardiac dysfunction induced by ischemia/reperfusion in isolated rat hearts
Pharmacology
2000
61: 238-243
|
| 21670227 |
Mandl A et al.:
Puma deletion delays cardiac dysfunction in murine heart failure models through attenuation of apoptosis
Circulation
2011
124: 31-39
|
| 18064672 |
Walker WP et al.:
Genetic analysis of attractin homologs
Genesis
2007
45: 744-756
|
| 28126591 |
Hot B et al.:
FZD10-Galpha13 signalling axis points to a role of FZD10 in CNS angiogenesis
Cell. Signal.
2017
32: 93-103
|
| 19661457 |
Civelek M et al.:
Chronic endoplasmic reticulum stress activates unfolded protein response in arterial endothelium in regions of susceptibility to atherosclerosis
Circ. Res.
2009
105: 453-461
|
| 20062063 |
Holm H et al. et al.:
Several common variants modulate heart rate, PR interval and QRS duration
Nat. Genet.
2010
42: 117-122
|
| 26390057 |
Kato N et al. et al.:
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
Nat. Genet.
2015
47: 1282-1293
|
| 6218830 |
author information missing
Polyamine levels and diamine oxidase activity in hypertrophic heart of spontaneously hypertensive rats and of rats treated with isoproterenol
Biochim. Biophys. Acta
1983
755: 344-351
|
| 30100729 |
Biernawska J et al.:
Predisposition of functional genetic variants of A-kinase anchoring protein 10 toward acquired repolarization disorders in high-risk vascular surgery patients
Ther Clin Risk Manag
2018
14: 1315-1322
|
| 18851995 |
Liu Z et al.:
WNT signaling promotes Nkx2.5 expression and early cardiomyogenesis via downregulation of Hdac1
Biochim. Biophys. Acta
2009
1793: 300-311
|
| 30127295 |
Haase T et al. et al.:
Novel DNA Methylation Sites Influence GPR15 Expression in Relation to Smoking
|
| 32100368 |
Yellamilli A et al.:
Abcg2-expressing side population cells contribute to cardiomyocyte renewal through fusion
FASEB J.
2020
34: 5642-5657
|
| 29271489 |
Batori R et al.:
Differential mechanisms of adenosine- and ATPgammaS-induced microvascular endothelial barrier strengthening
J. Cell. Physiol.
2019
234: 5863-5879
|
| 16856840 |
Lygren B et al.:
Compartmentalized cAMP signalling is important in the regulation of Ca(2+) cycling in the heart
Biochem. Soc. Trans.
2006
34: 489-491
|
| 18485437 |
Yang Y et al.:
Endothelial glutathione-S-transferase A4-4 protects against oxidative stress and modulates iNOS expression through NF-kappaB translocation
Toxicol. Appl. Pharmacol.
2008
230: 187-196
|
| 28051329 |
Arnold N et al.:
Regulation of the cardioprotective adiponectin and its receptor AdipoR1 by salt
Can. J. Physiol. Pharmacol.
2017
95: 305-309
|
| 21552570 |
Park M et al.:
Globular adiponectin, acting via AdipoR1/APPL1, protects H9c2 cells from hypoxia/reoxygenation-induced apoptosis
PLoS ONE
2011
6
|
| 28468790 |
Agopian AJ et al.:
Genome-Wide Association Studies and Meta-Analyses for Congenital Heart Defects
Circ Cardiovasc Genet
2017
10
|
| 30919020 |
van de Vegte YJ et al.:
Genetics and the heart rate response to exercise
Cell. Mol. Life Sci.
2019
76: 2391-2409
|
| 17043168 |
Chittenden TW et al.:
Transcriptional profiling in coronary artery disease: indications for novel markers of coronary collateralization
Circulation
2006
114: 1811-1820
|
| 31595165 |
Deng Y et al.:
Circ-HIPK3 Strengthens the Effects of Adrenaline in Heart Failure by MiR-17-3p - ADCY6 Axis
Int. J. Biol. Sci.
2019
15: 2484-2496
|
| 23778083 |
Singh KK et al.:
Autophagy gene fingerprint in human ischemia and reperfusion
J. Thorac. Cardiovasc. Surg.
2014
147: 1065-1072.e1
|
| 30338214 |
Roussel E et al.:
Multiple short-chain dehydrogenases/reductases are regulated in pathological cardiac hypertrophy
FEBS Open Bio
2018
8: 1624-1635
|
| 10545522 |
McConnell BK et al. et al.:
Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice
J. Clin. Invest.
1999
104: 1235-1244
|
| 10024460 |
Gruen M et al.:
Mutations in beta-myosin S2 that cause familial hypertrophic cardiomyopathy (FHC) abolish the interaction with the regulatory domain of myosin-binding protein-C
J. Mol. Biol.
1999
286: 933-949
|
| 26074085 |
Sheikh F et al.:
Functions of myosin light chain-2 (MYL2) in cardiac muscle and disease
Gene
2015
569: 14-20
|
| 26232335 |
Li MX et al.:
Structure and function of cardiac troponin C (TNNC1): Implications for heart failure, cardiomyopathies, and troponin modulating drugs
Gene
2015
571: 153-166
|
| 22955375 |
England J et al.:
Heavy and light roles: myosin in the morphogenesis of the heart
Cell. Mol. Life Sci.
2013
70: 1221-1239
|
| 24578694 |
Kurtenbach S et al.:
Gap junction modulation and its implications for heart function
Front Physiol
2014
5: 82
|
| 26010093 |
Dalpiaz PL et al.:
Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats
PLoS ONE
2015
10
|
| 24850809 |
Verweij N et al.:
Genetic determinants of P wave duration and PR segment
Circ Cardiovasc Genet
2014
7: 475-481
|
| 21720541 |
Maas NM et al.:
The C20orf133 gene is disrupted in a patient with Kabuki syndrome
|
| 11549352 |
Bloem LJ et al.:
Tissue distribution and functional expression of a cDNA encoding a novel mixed lineage kinase
J. Mol. Cell. Cardiol.
2001
33: 1739-1750
|
| 21546879 |
Demura M et al. et al.:
Multiple noncoding exons 1 of nuclear receptors NR4A family (nerve growth factor-induced clone B, Nur-related factor 1 and neuron-derived orphan receptor 1) and NR5A1 (steroidogenic factor 1) in human cardiovascular and adrenal tissues
J. Hypertens.
2011
29: 1185-1195
|
| 23581889 |
Zhang L et al.:
Lowered Nudix type 5 expression leads to cellular senescence in IMR-90 fibroblast cells
Free Radic. Res.
2013
47: 511-516
|
| 19404486 |
Li B et al.:
Overexpression of nuclear transport factor 2 may protect against diabetic retinopathy
Mol. Vis.
2009
15: 861-869
|
| 31396918 |
Starup-Linde J et al.:
Osteoglycin and Bone-a Systematic Review
Curr Osteoporos Rep
2019
17: 250-255
|
| 28958774 |
Deckx S et al. et al.:
Osteoglycin prevents the development of age-related diastolic dysfunction during pressure overload by reducing cardiac fibrosis and inflammation
Matrix Biol.
2018
66: 110-124
|
| 22009730 |
Goettsch C et al.:
The osteoclast-associated receptor (OSCAR) is a novel receptor regulated by oxidized low-density lipoprotein in human endothelial cells
Endocrinology
2011
152: 4915-4926
|
| 29107716 |
Semmler J et al.:
Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart
Pharmacol. Res.
2018
128: 200-210
|
| 28965749 |
Lee C et al.:
Platelet-derived growth factor-C and -D in the cardiovascular system and diseases
Mol. Aspects Med.
2018
62: 12-21
|
| 26751588 |
Gu L et al.:
The Histone Demethylase PHF8 Is Essential for Endothelial Cell Migration
PLoS ONE
2016
11
|
| 27841878 |
Hoffmann TJ et al.:
Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation
Nat. Genet.
2017
49: 54-64
|
| 31564129 |
Sakaguchi T et al. et al.:
Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of Its Interaction With Actin
Circulation
2019
140: 1737-1752
|
| 29288726 |
Khurana S et al.:
Phenylethanolamine N-methyltransferase gene expression in PC12 cells exposed to intermittent hypoxia
Neurosci. Lett.
2018
666: 169-174
|
| 14553966 |
Cui J et al.:
Association of polymorphisms in the promoter region of the PNMT gene with essential hypertension in African Americans but not in whites
Am. J. Hypertens.
2003
16: 859-863
|
| 26244553 |
Che P et al.:
Spinophilin Is Indispensable for the alpha2B Adrenergic Receptor-Elicited Hypertensive Response
PLoS ONE
2015
10
|
| 19486520 |
McGrath MF et al.:
Transcriptional analysis of the mammalian heart with special reference to its endocrine function
BMC Genomics
2009
10: 254
|
| 25409743 |
Zhang CF et al.:
MicroRNA-136 Promotes Vascular Muscle Cell Proliferation Through the ERK1/2 Pathway by Targeting PPP2R2A in Atherosclerosis
Curr Vasc Pharmacol
2015
13: 405-412
|
| 24425002 |
Varadkar P et al.:
The protein phosphatase 2A B56gamma regulatory subunit is required for heart development
Dev Dyn
2014
243: 778-790
|
| 18423039 |
Maresh JG et al.:
In vivo endothelial gene regulation in diabetes
Cardiovasc Diabetol
2008
7: 8
|
| 17562528 |
Canatan H et al.:
The effect of cardiac ischemic preconditioning on rat left ventricular gene expression profile
Cell Biochem. Funct.
2008
26: 179-184
|
| 29794156 |
Atkinson SJ et al. et al.:
The beta3-integrin endothelial adhesome regulates microtubule-dependent cell migration
|
| 21962426 |
Lin D et al. et al.:
Molecular signatures of end-stage heart failure
J. Card. Fail.
2011
17: 867-874
|
| 27284300 |
Ming Z et al.:
Differential co-expression analysis of venous thromboembolism based on gene expression profile data
Exp Ther Med
2016
11: 2193-2200
|
| 28386842 |
Qiu C et al.:
Vitamin K2 inhibits rat vascular smooth muscle cell calcification by restoring the Gas6/Axl/Akt anti-apoptotic pathway
Mol. Cell. Biochem.
2017
433: 149-159
|
| 22034491 |
Oikonomopoulos A et al. et al.:
Wnt signaling exerts an antiproliferative effect on adult cardiac progenitor cells through IGFBP3
Circ. Res.
2011
109: 1363-1374
|
| 15327998 |
Fujio Y et al.:
Signals through gp130 upregulate Wnt5a and contribute to cell adhesion in cardiac myocytes
FEBS Lett.
2004
573: 202-206
|
| 26153423 |
Jiang J et al.:
Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis
Proc. Natl. Acad. Sci. U.S.A.
2015
112: 9046-9051
|
| 32072603 |
Li N et al.:
Lin28B/miR-92b Promote the Proliferation, Migration, and Invasion in the Pathogenesis of Preeclampsia via the DKK1/Wnt/beta-Catenin Pathway
Reprod Sci
2020
27: 815-822
|
| 24563511 |
Bie J et al.:
Liver-specific transgenic expression of cholesteryl ester hydrolase reduces atherosclerosis in Ldlr-/- mice
J. Lipid Res.
2014
55: 729-738
|
| 29769521 |
Ramirez J et al.:
Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system
Nat Commun
2018
9: 1947
|
| 30143541 |
Li L et al.:
Pitx2 maintains mitochondrial function during regeneration to prevent myocardial fat deposition
|
| 22935419 |
Adachi A et al.:
NFAT5 regulates the canonical Wnt pathway and is required for cardiomyogenic differentiation
Biochem. Biophys. Res. Commun.
2012
426: 317-323
|
| 26378684 |
Mangino M et al.:
Integrated multiomics approach identifies calcium and integrin-binding protein-2 as a novel gene for pulse wave velocity
J. Hypertens.
2016
34: 79-87
|
| 29343526 |
van den Berg MP et al. et al.:
Mutations in CYB561 Causing a Novel Orthostatic Hypotension Syndrome
Circ Res
2018
122: 846-854
|
| 32703415 |
Hironaka T et al.:
Drebrin is induced during myofibroblast differentiation and enhances the production of fibrosis-related genes
Biochem Biophys Res Commun
2020
529: 224-230
|
| 31756066 |
Maciorkowska M et al.:
Adropin and irisin in arterial hypertension, diabetes mellitus and chronic kidney disease
Adv Clin Exp Med
2019
28: 1571-1575
|
| 30923760 |
Nishihama N et al.:
Mice lacking fat storage-inducing transmembrane protein 2 show improved profiles upon pressure overload-induced heart failure
Heliyon
2019
5
|
| 20416888 |
Ghorbel MT et al.:
Transcriptomic analysis of patients with tetralogy of Fallot reveals the effect of chronic hypoxia on myocardial gene expression
J Thorac Cardiovasc Surg
2010
140: 337-345.e26
|
| 31595394 |
Xu H et al.:
mRNA Expression Profiles from Whole Blood Associated with Vasospasm in Patients with Subarachnoid Hemorrhage
Neurocrit Care
2020
33: 82-89
|
| 9837777 |
Kroll J et al.:
VEGF-A induces expression of eNOS and iNOS in endothelial cells via VEGF receptor-2 (KDR)
Biochem Biophys Res Commun
1998
252: 743-746
|
| 1417831 |
Terman BI et al.:
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
Biochem Biophys Res Commun
1992
187: 1579-1586
|
| 16436494 |
Nakagawa T et al.:
Uncoupling of vascular endothelial growth factor with nitric oxide as a mechanism for diabetic vasculopathy
J Am Soc Nephrol
2006
17: 736-745
|
| 11807828 |
Wang J et al.:
Induction of KDR expression in bovine arterial endothelial cells by thrombin: involvement of nitric oxide
J Cell Physiol
2002
190: 238-250
|
| 10446165 |
Tsopanoglou NE et al.:
On the mechanism of thrombin-induced angiogenesis. Potentiation of vascular endothelial growth factor activity on endothelial cells by up-regulation of its receptors
J Biol Chem
1999
274
|
| 18267956 |
Mahadev K et al.:
Adiponectin inhibits vascular endothelial growth factor-induced migration of human coronary artery endothelial cells
Cardiovasc Res
2008
78: 376-384
|
| 28684444 |
Randi AM et al.:
Angiogenesis and the ADAMTS13-VWF balance
Blood
2017
130: 1-2
|
| 21899046 |
author information missing
[Mechanism of inhibitory effect of angiostatin on plasminogen activation by its physiologic activators]
Bioorg Khim
2011
37: 319-326
|
| 30383449 |
Vrakas CN et al.:
RNA stability protein ILF3 mediates cytokine-induced angiogenesis
FASEB J
2019
33: 3304-3316
|
| 20966397 |
Jain S et al.:
The anti-inflammatory cytokine interleukin 19 is expressed by and angiogenic for human endothelial cells
Arterioscler Thromb Vasc Biol
2011
31: 167-175
|
| 27053520 |
Kako F et al.:
Interleukin-19 induces angiogenesis in the absence of hypoxia by direct and indirect immune mechanisms
Am J Physiol Cell Physiol
2016
310: C931-C941
|
| 28642237 |
Bai L et al. et al.:
Mediator 1 Is Atherosclerosis Protective by Regulating Macrophage Polarization
Arterioscler Thromb Vasc Biol
2017
37: 1470-1481
|
| 17548836 |
Ge G et al.:
Bone morphogenetic protein 1 processes prolactin to a 17-kDa antiangiogenic factor
Proc Natl Acad Sci U S A
2007
104
|
| 21273553 |
Leksa V et al. et al.:
Soluble M6P/IGF2R released by TACE controls angiogenesis via blocking plasminogen activation
Circ Res
2011
108: 676-685
|
| 11557572 |
Brodsky S et al.:
Plasmin-dependent and -independent effects of plasminogen activators and inhibitor-1 on ex vivo angiogenesis
Am J Physiol Heart Circ Physiol
2001
281
|
| 20395596 |
Luo Y et al.:
Endothelial-specific transgenesis of TNFR2 promotes adaptive arteriogenesis and angiogenesis
Arterioscler Thromb Vasc Biol
2010
30: 1307-1314
|
| 9631868 |
Nickenig G et al.:
Estrogen modulates AT1 receptor gene expression in vitro and in vivo
Circulation
1998
97: 2197-2201
|
| 28661206 |
Bukowska A et al.:
Protective regulation of the ACE2/ACE gene expression by estrogen in human atrial tissue from elderly men
Exp Biol Med (Maywood)
2017
242: 1412-1423
|
| 33352807 |
Ikeda Y et al.:
Relationship between Soluble (pro)Renin Receptor and Renin Activity in Patients with Severe Heart Failure
|
| 21270819 |
Yoshikawa A et al.:
The (pro)renin receptor is cleaved by ADAM19 in the Golgi leading to its secretion into extracellular space
Hypertens Res
2011
34: 599-605
|
| 4322742 |
author information missing
A dipeptidyl carboxypeptidase that converts angiotensin I and inactivates bradykinin
Biochim Biophys Acta
1970
214: 374-376
|
| 15096597 |
Akiyama H et al.:
Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa
Proc Natl Acad Sci U S A
2004
101: 6502-6507
|
| 17352389 |
Smyk M et al.:
Recurrent SOX9 deletion campomelic dysplasia due to somatic mosaicism in the father
Am J Med Genet A
2007
143A: 866-870
|
| 21463877 |
author information missing
article information missing
|
| 34260266 |
author information missing
article information missing
|
| 35017523 |
author information missing
article information missing
|
| 32489964 |
author information missing
article information missing
|
| 10545518 |
author information missing
article information missing
|
| 23129134 |
author information missing
article information missing
|
| 15265759 |
author information missing
article information missing
|
| 21550412 |
author information missing
article information missing
|
| 16701909 |
Phrommintikul A et al.:
Roles of cardiac ryanodine receptor in heart failure and sudden cardiac death
Int. J. Cardiol.
2006
112: 142-152
|
| 12673799 |
Wehrens XH et al.:
A novel mutation L619F in the cardiac Na+ channel SCN5A associated with long-QT syndrome (LQT3): a role for the I-II linker in inactivation gating
Hum. Mutat.
2003
21: 552
|
| 19556521 |
Liu Q et al.:
Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach
Circ. Res.
2009
105: 194-200
|
| 15339904 |
Kang Y et al.:
Syntaxin-1A inhibits cardiac KATP channels by its actions on nucleotide binding folds 1 and 2 of sulfonylurea receptor 2A
J Biol Chem
2004
279
|
| 14642002 |
Ning L et al.:
Denaturing high-performance liquid chromatography quickly and reliably detects cardiac ion channel mutations in long QT syndrome
Genet. Test.
2003
7: 249-253
|
| 25171807 |
Smolina N et al.:
Aggregate-prone desmin mutations impair mitochondrial calcium uptake in primary myotubes
Cell Calcium
2014
56: 269-275
|
| 19022376 |
Muchir A et al.:
Reduced expression of A-type lamins and emerin activates extracellular signal-regulated kinase in cultured cells
Biochim. Biophys. Acta
2009
1792: 75-81
|
| 19997769 |
Wheeler MA et al.:
Identification of an emerin-beta-catenin complex in the heart important for intercalated disc architecture and beta-catenin localisation
Cell. Mol. Life Sci.
2010
67: 781-796
|
| 17673255 |
Qu J et al.:
Cardiac-specific haploinsufficiency of beta-catenin attenuates cardiac hypertrophy but enhances fetal gene expression in response to aortic constriction
J. Mol. Cell. Cardiol.
2007
43: 319-326
|
| 11807557 |
Tan HL et al.:
A calcium sensor in the sodium channel modulates cardiac excitability
Nature
2002
415: 442-447
|
| 17098824 |
Sekiguchi K et al.:
Inhibition of PPAR-alpha activity in mice with cardiac-restricted expression of tumor necrosis factor: potential role of TGF-beta/Smad3
Am. J. Physiol. Heart Circ. Physiol.
2007
292
|
| 23417040 |
Shaw RM et al.:
L-type calcium channel targeting and local signalling in cardiac myocytes
Cardiovasc. Res.
2013
98: 177-186
|
| 22666394 |
Traister A et al.:
ILK induces cardiomyogenesis in the human heart
PLoS ONE
2012
7
|
| 24454898 |
Zaveri HP et al.:
Identification of critical regions and candidate genes for cardiovascular malformations and cardiomyopathy associated with deletions of chromosome 1p36
PLoS ONE
2014
9
|
| 23398819 |
Clarke SL et al.:
Barth syndrome
Orphanet J Rare Dis
2013
8: 23
|
| 20582536 |
Schwenk RW et al.:
Requirement for distinct vesicle-associated membrane proteins in insulin- and AMP-activated protein kinase (AMPK)-induced translocation of GLUT4 and CD36 in cultured cardiomyocytes
Diabetologia
2010
53: 2209-2219
|
| 22859947 |
Vacchi-Suzzi C et al.:
Perturbation of microRNAs in rat heart during chronic doxorubicin treatment
PLoS ONE
2012
7
|
| 27941310 |
Gong K et al.:
Smad3-mSin3A-HDAC1 Complex is Required for TGF-beta1-Induced Transcriptional Inhibition of PPARgamma in Mouse Cardiac Fibroblasts
Cell. Physiol. Biochem.
2016
40: 908-920
|
| 25921236 |
Sparks LM et al.:
A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle
Diabetes
2005
54: 1926-1933
|
| 20965886 |
Haghikia A et al. et al.:
Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes
Eur. Heart J.
2011
32: 1287-1297
|
| 24330504 |
Desai MS et al.:
Cardiomyopathy reverses with recovery of liver injury, cholestasis and cholanemia in mouse model of biliary fibrosis
Liver Int.
2015
35: 1464-1477
|
| 23046516 |
Lai HL et al.:
Maintenance of adult cardiac function requires the chromatin factor Asxl2
J. Mol. Cell. Cardiol.
2012
53: 734-741
|
| 26086101 |
Clemen CS et al. et al.:
VCP and PSMF1: Antagonistic regulators of proteasome activity
Biochem. Biophys. Res. Commun.
2015
463: 1210-1217
|
| 25968336 |
Thoonen R et al. et al.:
Functional brown adipose tissue limits cardiomyocyte injury and adverse remodeling in catecholamine-induced cardiomyopathy
J. Mol. Cell. Cardiol.
2015
84: 202-211
|
| 31350035 |
Ju S et al.:
Low density lipoprotein receptor-related protein 1 regulates cardiac hypertrophy induced by pressure overload
Int. J. Cardiol.
2020
299: 235-242
|
| 31297131 |
author information missing
article information missing
|
| 17652099 |
Daw EW et al.:
Genome-wide mapping of modifier chromosomal loci for human hypertrophic cardiomyopathy
Hum. Mol. Genet.
2007
16: 2463-2471
|
| 21585276 |
Shehata BM et al.:
Identification of candidate genes for histiocytoid cardiomyopathy (HC) using whole genome expression analysis: analyzing material from the HC registry
Pediatr. Dev. Pathol.
2011
14: 370-377
|
| 12404107 |
Kabaeva ZT et al.:
Systematic analysis of the regulatory and essential myosin light chain genes: genetic variants and mutations in hypertrophic cardiomyopathy
Eur. J. Hum. Genet.
2002
10: 741-748
|
| 31778749 |
Wan X et al.:
Genes of the cGMP-PKG-Ca(2+) signaling pathway are alternatively spliced in cardiomyopathy: Role of RBFOX2
Biochim Biophys Acta Mol Basis Dis
2020
1866
|
| 27718144 |
Hedberg-Oldfors C et al.:
Cardiomyopathy as presenting sign of glycogenin-1 deficiency-report of three cases and review of the literature
J Inherit Metab Dis
2017
40: 139-149
|
| 28740084 |
Benson MA et al.:
Ryanodine receptors are part of the myospryn complex in cardiac muscle
Sci Rep
2017
7: 6312
|
| 32013205 |
Franaszczyk M et al. et al.:
Analysis of De Novo Mutations in Sporadic Cardiomyopathies Emphasizes Their Clinical Relevance and Points to Novel Candidate Genes
|
| 29154475 |
Zhang J et al.:
Identification and analysis of a key long non-coding RNAs (lncRNAs)-associated module reveal functional lncRNAs in cardiac hypertrophy
J. Cell. Mol. Med.
2018
22: 892-903
|
| 18957093 |
Ehlermann P et al.:
Adverse events in families with hypertrophic or dilated cardiomyopathy and mutations in the MYBPC3 gene
BMC Med. Genet.
2008
9: 95
|
| 32081420 |
Kosugi M et al.:
Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice
|
| 25637602 |
Kao DP et al.:
Therapeutic Molecular Phenotype of beta-Blocker-Associated Reverse-Remodeling in Nonischemic Dilated Cardiomyopathy
Circ Cardiovasc Genet
2015
8: 270-283
|
| 14660611 |
Arimura T et al. et al.:
A Cypher/ZASP mutation associated with dilated cardiomyopathy alters the binding affinity to protein kinase C
J. Biol. Chem.
2004
279: 6746-6752
|
| 24781756 |
Abdulhag UN et al.:
Mitochondrial complex IV deficiency, caused by mutated COX6B1, is associated with encephalomyopathy, hydrocephalus and cardiomyopathy
Eur. J. Hum. Genet.
2015
23: 159-164
|
| 24789905 |
author information missing
Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy
J. Clin. Invest.
2014
124: 2410-2424
|
| 27693233 |
Thompson K et al. et al.:
Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number
Am J Hum Genet
2016
99: 860-876
|
| 12967636 |
Shan YX et al.:
Hsp10 and Hsp60 modulate Bcl-2 family and mitochondria apoptosis signaling induced by doxorubicin in cardiac muscle cells
J Mol Cell Cardiol
2003
35: 1135-1143
|
| 37221250 |
author information missing
article information missing
|
| 23590259 |
Fokstuen S et al.:
Multiplex targeted high-throughput sequencing for Mendelian cardiac disorders
Clin. Genet.
2014
85: 365-370
|
| 18719600 |
Carling D et al.:
The regulation of AMP-activated protein kinase by upstream kinases.
Int J Obes (Lond)
2008
32: S55-S59
|
| 14614828 |
Woods A et al.:
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade
Curr. Biol.
2003
13: 2004-2008
|
| 22116099 |
Higashikuni Y et al.:
The ATP-binding cassette transporter ABCG2 protects against pressure overload-induced cardiac hypertrophy and heart failure by promoting angiogenesis and antioxidant response
Arterioscler. Thromb. Vasc. Biol.
2012
32: 654-661
|
| 24530811 |
Tucci S et al.:
Development and pathomechanisms of cardiomyopathy in very long-chain acyl-CoA dehydrogenase deficient (VLCAD(-/-)) mice
Biochim. Biophys. Acta
2014
1842: 677-685
|
| 18830417 |
Kerkela R et al.:
Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation
J. Clin. Invest.
2008
118: 3609-3618
|
| 22912742 |
Sysa-Shah P et al.:
Cardiac-specific over-expression of epidermal growth factor receptor 2 (ErbB2) induces pro-survival pathways and hypertrophic cardiomyopathy in mice
PLoS ONE
2012
7
|
| 18502941 |
Dallabrida SM et al.:
Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy
FASEB J.
2008
22: 3010-3023
|
| 16374517 |
Peng X et al.:
Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice
J. Clin. Invest.
2006
116: 217-227
|
| 17261657 |
Peng J et al.:
Cardiac hypertrophy and reduced contractility in hearts deficient in the titin kinase region
Circulation
2007
115: 743-751
|
| 14982994 |
Pan Y et al.:
Identification of biochemical adaptations in hyper- or hypocontractile hearts from phospholamban mutant mice by expression proteomics
Proc. Natl. Acad. Sci. U.S.A.
2004
101: 2241-2246
|
| 23224875 |
Menick DR et al.:
Transcriptional pathways and potential therapeutic targets in the regulation of Ncx1 expression in cardiac hypertrophy and failure
Adv. Exp. Med. Biol.
2013
961: 125-135
|
| 23044624 |
Chen AL et al.:
Effect of hepatocyte growth factor and angiotensin II on rat cardiomyocyte hypertrophy
Braz. J. Med. Biol. Res.
2012
45: 1150-1156
|
| 17088456 |
Lu H et al.:
Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice
Circulation
2006
114: 2271-2279
|
| 30102008 |
Yan K et al.:
The role of K63-linked polyubiquitination in cardiac hypertrophy
J. Cell. Mol. Med.
2018
22: 4558-4567
|
| 24743145 |
author information missing
Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy
J. Clin. Invest.
2014
124: 2136-2146
|
| 24865491 |
Su M et al.:
Rare variants in genes encoding MuRF1 and MuRF2 are modifiers of hypertrophic cardiomyopathy
Int J Mol Sci
2014
15: 9302-9313
|
| 27891585 |
Verrigni D et al. et al.:
Novel mutations in KARS cause hypertrophic cardiomyopathy and combined mitochondrial respiratory chain defect
Clin. Genet.
2017
91: 918-923
|
| 23939492 |
Spiltoir JI et al.:
BET acetyl-lysine binding proteins control pathological cardiac hypertrophy
J. Mol. Cell. Cardiol.
2013
63: 175-179
|
| 23840593 |
Wang Y et al. et al.:
Autosomal recessive transmission of MYBPC3 mutation results in malignant phenotype of hypertrophic cardiomyopathy
PLoS ONE
2013
8
|
| 15059932 |
Palmer BM et al. et al.:
Role of cardiac myosin binding protein C in sustaining left ventricular systolic stiffening
Circ. Res.
2004
94: 1249-1255
|
| 32341788 |
Adalsteinsdottir B et al.:
Hypertrophic cardiomyopathy in myosin-binding protein C (MYBPC3) Icelandic founder mutation carriers
Open Heart
2020
7
|
| 11815426 |
Niimura H et al.:
Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly
Circulation
2002
105: 446-451
|
| 16679492 |
author information missing
Two cases of severe neonatal hypertrophic cardiomyopathy caused by compound heterozygous mutations in the MYBPC3 gene
J. Med. Genet.
2006
43: 829-832
|
| 30550750 |
O'Leary TS et al.:
MYBPC3 truncation mutations enhance actomyosin contractile mechanics in human hypertrophic cardiomyopathy
J. Mol. Cell. Cardiol.
2019
127: 165-173
|
| 29706351 |
Cornec-Le Gall E et al. et al.:
Monoallelic Mutations to DNAJB11 Cause Atypical Autosomal-Dominant Polycystic Kidney Disease
Am J Hum Genet
2018
102: 832-844
|
| 28209092 |
He J et al.:
Fibroblast growth factor-1 (FGF-1) promotes adipogenesis by downregulation of carboxypeptidase A4 (CPA4) - a negative regulator of adipogenesis implicated in the modulation of local and systemic insulin sensitivity
Growth Factors
2016
34: 210-216
|
| 28630369 |
author information missing
article information missing
|
| 25137373 |
Molina-Navarro MM et al.:
Functional networks of nucleocytoplasmic transport-related genes differentiate ischemic and dilated cardiomyopathies. A new therapeutic opportunity
PLoS ONE
2014
9
|
| 25884818 |
Herrer I et al.:
Gene expression network analysis reveals new transcriptional regulators as novel factors in human ischemic cardiomyopathy
BMC Med Genomics
2015
8: 14
|
| 27472518 |
author information missing
article information missing
|
| 14657064 |
Pepine CJ et al.:
A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International Verapamil-Trandolapril Study (INVEST): a randomized controlled trial
JAMA
2003
290: 2805-2816
|
| 21423583 |
Muendlein A et al.:
Single nucleotide polymorphisms of TCF7L2 are linked to diabetic coronary atherosclerosis.
PLoS ONE
2011
6
|
| 22643843 |
Perla-Kajan J et al.:
Paraoxonase 1 and homocysteine metabolism
Amino Acids
2012
43: 1405-1417
|
| 20173117 |
Shah SH et al.:
Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events
Circ Cardiovasc Genet
2010
3: 207-214
|
| 20686565 |
Teslovich TM et al.:
Biological, clinical and population relevance of 95 loci for blood lipids
Nature
2010
466: 707-713
|
| 24097068 |
Willer CJ et al. et al.:
Discovery and refinement of loci associated with lipid levels
Nat. Genet.
2013
45: 1274-1283
|
| 16946132 |
Brunham LR et al.:
Tissue-specific induction of intestinal ABCA1 expression with a liver X receptor agonist raises plasma HDL cholesterol levels
Circ. Res.
2006
99: 672-674
|
| 21733517 |
Jiang F et al.:
Fine mapping of chromosome 3q22.3 identifies two haplotype blocks in ESYT3 associated with coronary artery disease in female Han Chinese
Atherosclerosis
2011
218: 397-403
|
| 24704371 |
Wang Z et al.:
Epigenetic upregulation of PSD-95 contributes to the rewarding behavior by morphine conditioning
Eur. J. Pharmacol.
2014
732: 123-129
|
| 23701246 |
Bian W et al.:
Stabilization of the angiotensin-(1-7) receptor Mas through interaction with PSD95
Biochem. J.
2013
453: 345-356
|
| 23664202 |
Dohi T et al.:
Increased lysophosphatidic acid levels in culprit coronary arteries of patients with acute coronary syndrome
Atherosclerosis
2013
229: 192-197
|
| 27694435 |
author information missing
article information missing
|
| 24504738 |
author information missing
article information missing
|
| 26034042 |
Wu C et al.:
Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic Forces
Circ. Res.
2015
117: E41-E53
|
| 25835000 |
Reschen ME et al.:
Lipid-induced epigenomic changes in human macrophages identify a coronary artery disease-associated variant that regulates PPAP2B Expression through Altered C/EBP-beta binding
PLoS Genet.
2015
11
|
| 26494228 |
author information missing
article information missing
|
| 27846466 |
author information missing
article information missing
|
| 23104851 |
Panchatcharam M et al.:
Lipid phosphate phosphatase 3 negatively regulates smooth muscle cell phenotypic modulation to limit intimal hyperplasia
Arterioscler. Thromb. Vasc. Biol.
2013
33: 52-59
|
| 26015811 |
Steenaard RV et al.:
Tobacco smoking is associated with methylation of genes related to coronary artery disease
Clin Epigenetics
2015
7: 54
|
| 24262325 |
Dichgans M et al.:
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants
Stroke
2014
45: 24-36
|
| 20370486 |
Listi F et al.:
Association between platelet endothelial cellular adhesion molecule-1 polymorphisms and atherosclerosis: results of a study on patients from northern Italy
Rejuvenation Res
2010
13: 237-241
|
| 23667179 |
Erbilgin A et al.:
Identification of CAD candidate genes in GWAS loci and their expression in vascular cells
J. Lipid Res.
2013
54: 1894-1905
|
| 28013181 |
Meza D et al.:
Platelets modulate endothelial cell response to dynamic shear stress through PECAM-1
Thromb. Res.
2017
150: 44-50
|
| 25249547 |
author information missing
Candidate pathway-based genome-wide association studies identify novel associations of genomic variants in the complement system associated with coronary artery disease
Circ Cardiovasc Genet
2014
7: 887-894
|
| 19433579 |
Watanabe J et al.:
Hemoglobin and its scavenger protein haptoglobin associate with apoA-1-containing particles and influence the inflammatory properties and function of high density lipoprotein
J. Biol. Chem.
2009
284
|
| 26822151 |
Hartiala JA et al.:
Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease
Nat Commun
2016
7: 10558
|
| 28123922 |
Rahim S et al.:
Serum Apo A-1 and Its Role as a Biomarker of Coronary Artery Disease
Cureus
2016
8: e941
|
| 27350024 |
Basak T et al.:
Plasma proteomic analysis of stable coronary artery disease indicates impairment of reverse cholesterol pathway
Sci Rep
2016
6: 28042
|
| 17803810 |
Cavallari U et al.:
Gene sequence variations of the platelet P2Y12 receptor are associated with coronary artery disease
BMC Med. Genet.
2007
8: 59
|
| 26602883 |
Bastami M et al.:
Evaluating the association of common UBE2Z variants with coronary artery disease in an Iranian population
Cell. Mol. Biol. (Noisy-le-grand)
2015
61: 50-54
|
| 28082312 |
Kristariyanto YA et al.:
A single MIU motif of MINDY-1 recognizes K48-linked polyubiquitin chains
EMBO Rep.
2017
18: 392-402
|
| 28840129 |
Lu D et al.:
Rs46522 in the Ubiquitin-Conjugating Enzyme E2Z Gene Is Associated with the Risk of Coronary Artery Disease in Individuals of Chinese Han Population with Type 2 Diabetes
J Diabetes Res
2017
2017
|
| 21378990 |
Schunkert H et al. et al.:
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
Nat. Genet.
2011
43: 333-338
|
| 24573017 |
Dechamethakun S et al.:
Associations between the CDKN2A/B, ADTRP and PDGFD polymorphisms and the development of coronary atherosclerosis in Japanese patients
J. Atheroscler. Thromb.
2014
21: 680-690
|
| 17597759 |
Jin J et al.:
Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging
Nature
2007
447: 1135-1138
|
| 20975683 |
Aichem A et al.:
USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis
Nat Commun
2010
1: 13
|
| 30718280 |
Bialas J et al.:
The ubiquitin-like modifier FAT10 stimulates the activity of the deubiquitylating enzyme OTUB1
|
| 25578447 |
Foroughi Asl H et al. et al.:
Expression quantitative trait Loci acting across multiple tissues are enriched in inherited risk for coronary artery disease
Circ Cardiovasc Genet
2015
8: 305-315
|
| 27879314 |
Shimizu C et al. et al.:
Genetic Variation in the SLC8A1 Calcium Signaling Pathway Is Associated With Susceptibility to Kawasaki Disease and Coronary Artery Abnormalities
Circ Cardiovasc Genet
2016
9: 559-568
|
| 29695241 |
Charmet R et al.:
Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes
Cardiovasc Diabetol
2018
17: 61
|
| 22666496 |
Shiffman D et al. et al.:
Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy
PLoS ONE
2012
7
|
| 25092108 |
Lee BJ et al.:
Effects of L-carnitine supplementation on oxidative stress and antioxidant enzymes activities in patients with coronary artery disease: a randomized, placebo-controlled trial
Nutr J
2014
13: 79
|
| 32667867 |
author information missing
article information missing
|
| 35252377 |
author information missing
article information missing
|
| 18192653 |
Nagle CA et al.:
Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- mice
J. Lipid Res.
2008
49: 823-831
|
| 18927507 |
Kamagate A et al.:
FoxO1 integrates insulin signaling to VLDL production.
Cell Cycle
2008
7: 3162-3170
|
| 18439917 |
Zhang C et al.:
Role of NonO-histone interaction in TNFalpha-suppressed prolyl-4-hydroxylase alpha1.
Biochim. Biophys. Acta
2008
1783: 1517-1528
|
| 15472203 |
Dandona P et al.:
Increased plasma concentration of macrophage migration inhibitory factor (MIF) and MIF mRNA in mononuclear cells in the obese and the suppressive action of metformin
J. Clin. Endocrinol. Metab.
2004
89: 5043-5047
|
| 8901609 |
Velloso LA et al.:
Cross-talk between the insulin and angiotensin signaling systems
Proc. Natl. Acad. Sci. U.S.A.
1996
93
|
| 20228403 |
McMurray JJ et al.:
Effect of valsartan on the incidence of diabetes and cardiovascular events
N. Engl. J. Med.
2010
362: 1477-1490
|
| 22134503 |
Ringseis R et al.:
Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine deficiency
Eur J Nutr
2012
1: 1-18
|
| 22833659 |
Clifford AJ et al.:
Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, CETP, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults
J. Nutr.
2012
142: 1764-1771
|
| 21436600 |
Kiso Y et al.:
Pharmacology in health foods: effects of arachidonic acid and docosahexaenoic acid on the age-related decline in brain and cardiovascular system function
J. Pharmacol. Sci.
2011
115: 471-475
|
| 23553151 |
Curtis PJ et al.:
Vascular function and atherosclerosis progression after 1 y of flavonoid intake in statin-treated postmenopausal women with type 2 diabetes: a double-blind randomized controlled trial
Am. J. Clin. Nutr.
2013
97: 936-942
|
| 22250063 |
Curtis PJ et al.:
Chronic ingestion of flavan-3-ols and isoflavones improves insulin sensitivity and lipoprotein status and attenuates estimated 10-year CVD risk in medicated postmenopausal women with type 2 diabetes: a 1-year, double-blind, randomized, controlled trial
Diabetes Care
2012
35: 226-232
|
| 21733722 |
Innes KE et al.:
Restless legs syndrome and conditions associated with metabolic dysregulation, sympathoadrenal dysfunction, and cardiovascular disease risk: a systematic review
Sleep Med Rev
2012
4: 309-339
|
| 17374715 |
Lu G et al.:
A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development
Genes Dev.
2007
21: 784-796
|
| 8560269 |
Acton S et al.:
Identification of scavenger receptor SR-BI as a high density lipoprotein receptor
Science
1996
271: 518-520
|
| 18947868 |
Dally S et al.:
Compartmentalized expression of three novel sarco/endoplasmic reticulum Ca2+ATPase 3 isoforms including the switch to ER stress, SERCA3f, in non-failing and failing human heart
Cell Calcium
2009
45: 144-154
|
| 21965681 |
Mohamed TM et al.:
Plasma membrane calcium pump (PMCA4)-neuronal nitric-oxide synthase complex regulates cardiac contractility through modulation of a compartmentalized cyclic nucleotide microdomain
J. Biol. Chem.
2011
286
|
| 12933703 |
Gros R et al.:
Plasma membrane calcium ATPase overexpression in arterial smooth muscle increases vasomotor responsiveness and blood pressure
Circ. Res.
2003
93: 614-621
|
| 18221109 |
Ochi R et al.:
Ryanodine receptor: a novel therapeutic target in heart disease
Recent Pat Cardiovasc Drug Discov
2007
2: 110-118
|
| 16580578 |
El Midaoui A et al.:
Modulation of cardiac and aortic peroxisome proliferator-activated receptor-gamma expression by oxidative stress in chronically glucose-fed rats
Am. J. Hypertens.
2006
19: 407-412
|
| 16580578 |
El Midaoui A et al.:
Modulation of cardiac and aortic peroxisome proliferator-activated receptor-gamma expression by oxidative stress in chronically glucose-fed rats
Am. J. Hypertens.
2006
19: 407-412
|
| 20302927 |
Blanquicett C et al.:
Oxidative stress modulates PPAR gamma in vascular endothelial cells
Free Radic. Biol. Med.
2010
48: 1618-1625
|
| 23844512 |
et al.:
[To the mechanisms of antiarrhythmic action of Allapinine]
Bioorg. Khim.
2013
39: 105-116
|
| 22078798 |
Choi JH et al.:
Flt3 signaling-dependent dendritic cells protect against atherosclerosis
Immunity
2011
35: 819-831
|
| 18276926 |
Duan SZ et al.:
Peroxisome proliferator-activated receptor-gamma-mediated effects in the vasculature
Circ. Res.
2008
102: 283-294
|
| 10073956 |
Marx N et al.:
PPARgamma activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARgamma as a potential mediator in vascular disease
Arterioscler. Thromb. Vasc. Biol.
1999
19: 546-551
|
| 24113457 |
Alzoubi A et al.:
TRPC4 inactivation confers a survival benefit in severe pulmonary arterial hypertension
Am. J. Pathol.
2013
183: 1779-1788
|
| 9422509 |
Jiang C et al.:
PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
Nature
1998
391: 82-86
|
| 10843708 |
Marx N et al.:
Peroxisome proliferator-activated receptor-gamma activators inhibit IFN-gamma-induced expression of the T cell-active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells
J. Immunol.
2000
164: 6503-6508
|
| 10512746 |
Chen NG et al.:
PPARgamma agonists enhance human vascular endothelial adhesiveness by increasing ICAM-1 expression
Biochem. Biophys. Res. Commun.
1999
263: 718-722
|
| 10645917 |
Pasceri V et al.:
Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators
Circulation
2000
101: 235-238
|
| 10479650 |
Jackson SM et al.:
Peroxisome proliferator-activated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction
Arterioscler. Thromb. Vasc. Biol.
1999
19: 2094-2104
|
| 15694007 |
Sasaki M et al.:
Troglitazone, a PPAR-gamma activator prevents endothelial cell adhesion molecule expression and lymphocyte adhesion mediated by TNF-alpha
BMC Physiol.
2005
5: 3
|
| 15117825 |
Verrier E et al.:
PPARgamma agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: role of diacylglycerol kinase
Circ. Res.
2004
94: 1515-1522
|
| 23150690 |
Karakas M et al.:
Low levels of serum 25-hydroxyvitamin D are associated with increased risk of myocardial infarction, especially in women: results from the MONICA/KORA Augsburg case-cohort study
J. Clin. Endocrinol. Metab.
2013
98: 272-280
|
| 24215469 |
Then C et al.:
Plasma Copeptin levels are inversely associated with Intima-Media-Thickness in Men: the Population-based KORA F4 Study
Cardiovasc Diabetol
2013
12: 168
|
| 16614755 |
Mergia E et al.:
Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system
J. Clin. Invest.
2006
116: 1731-1737
|
| 9769303 |
Nagai Y et al.:
Increased carotid artery intimal-medial thickness in asymptomatic older subjects with exercise-induced myocardial ischemia
Circulation
1998
98: 1504-1509
|
| 7510950 |
Knowles RG et al.:
Nitric oxide synthases in mammals
Biochem. J.
1994
298: 249-258
|
| 3131684 |
Palmer RM et al.:
Vascular endothelial cells synthesize nitric oxide from L-arginine
Nature
1988
333: 664-666
|
| 11509489 |
Taddei S et al.:
Age-related reduction of NO availability and oxidative stress in humans
Hypertension
2001
38: 274-279
|
| 9631871 |
Taddei S et al.:
Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension
Circulation
1998
97: 2222-2229
|
| 10906340 |
Reiter CD et al.:
Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite
J. Biol. Chem.
2000
275
|
| 9187601 |
Kooy NW et al.:
Extensive tyrosine nitration in human myocardial inflammation: evidence for the presence of peroxynitrite
Crit. Care Med.
1997
25: 812-819
|
| 8342632 |
Brady AJ et al.:
Nitric oxide attenuates cardiac myocyte contraction
Am. J. Physiol.
1993
265: H176-H182
|
| 7536096 |
Schulz R et al.:
The role of nitric oxide in cardiac depression induced by interleukin-1 beta and tumour necrosis factor-alpha
Br. J. Pharmacol.
1995
114: 27-34
|
| 24004504 |
Choe CU et al.:
Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from human and murine studies
Circulation
2013
128: 1451-1461
|
| 23980179 |
Yang J et al.:
Arginase regulates red blood cell nitric oxide synthase and export of cardioprotective nitric oxide bioactivity
Proc. Natl. Acad. Sci. U.S.A.
2013
110
|
| 22301267 |
Chen J et al.:
C-reactive protein down-regulates endothelial nitric oxide synthase expression and promotes apoptosis in endothelial progenitor cells through receptor for advanced glycation end-products
Gene
2012
496: 128-135
|
| 12922018 |
Mineo C et al.:
HDL stimulation of endothelial nitric oxide synthase: a novel mechanism of HDL action
Trends Cardiovasc. Med.
2003
13: 226-231
|
| 9506985 |
Wong JT et al.:
Lysophosphatidylcholine stimulates the release of arachidonic acid in human endothelial cells
J. Biol. Chem.
1998
273: 6830-6836
|
| 23969698 |
DiDonato JA et al.:
Function and distribution of apolipoprotein A1 in the artery wall are markedly distinct from those in plasma
Circulation
2013
128: 1644-1655
|
| 10764676 |
Pilon A et al.:
Apolipoprotein AII enrichment of HDL enhances their affinity for class B type I scavenger receptor but inhibits specific cholesteryl ester uptake
Arterioscler. Thromb. Vasc. Biol.
2000
20: 1074-1081
|
| 15113749 |
Herrera M et al.:
Endothelin stimulates endothelial nitric oxide synthase expression in the thick ascending limb
Am. J. Physiol. Renal Physiol.
2004
287: F231-F235
|
| 10519149 |
Marsen TA et al.:
Tyrosine-kinase-dependent regulation of the nitric oxide synthase gene by endothelin-1 in human endothelial cells
Pflugers Arch.
1999
438: 538-544
|
| 11376172 |
Tzourio C et al.:
Association between migraine and endothelin type A receptor (ETA -231 A/G) gene polymorphism
Neurology
2001
56: 1273-1277
|
| 21139021 |
Cindrova-Davies T et al.:
Soluble FLT1 sensitizes endothelial cells to inflammatory cytokines by antagonizing VEGF receptor-mediated signalling
Cardiovasc. Res.
2011
89: 671-679
|
| 21273556 |
Cole LK et al.:
Impaired phosphatidylcholine biosynthesis reduces atherosclerosis and prevents lipotoxic cardiac dysfunction in ApoE-/- Mice
Circ. Res.
2011
108: 686-694
|
| 22282588 |
Li F et al.:
eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype
J. Am. Soc. Nephrol.
2012
23: 652-660
|
| 11086993 |
Fang M et al.:
Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON
Neuron
2000
28: 183-193
|
| 22499993 |
Goncalves I et al.:
Evidence supporting a key role of Lp-PLA2-generated lysophosphatidylcholine in human atherosclerotic plaque inflammation
Arterioscler. Thromb. Vasc. Biol.
2012
32: 1505-1512
|
| 14616768 |
Benjafield AV et al.:
Association of EDNRA, but not WNK4 or FKBP1B, polymorphisms with essential hypertension
Clin. Genet.
2003
64: 433-438
|
| 8126072 |
Goligorsky MS et al.:
Termination of endothelin signaling: role of nitric oxide
J. Cell. Physiol.
1994
158: 485-494
|
| 2153712 |
Boulanger C et al.:
Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide
J. Clin. Invest.
1990
85: 587-590
|
| 9396733 |
Schweizer A et al.:
Human endothelin-converting enzyme (ECE-1): three isoforms with distinct subcellular localizations
Biochem. J.
1997
328: 871-877
|
| 7672512 |
Pollock DM et al.:
Endothelin receptors and calcium signaling
FASEB J.
1995
9: 1196-1204
|
| 7526714 |
McQuillan LP et al.:
Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms
Am. J. Physiol.
1994
267
|
| 16908409 |
Cheah JH et al.:
NMDA receptor-nitric oxide transmission mediates neuronal iron homeostasis via the GTPase Dexras1
Neuron
2006
51: 431-440
|
| 9931481 |
Phung YT et al.:
Both neuronal NO synthase and nitric oxide are required for PC12 cell differentiation: a cGMP independent pathway
Brain Res. Mol. Brain Res.
1999
64: 165-178
|
| 9449433 |
Dong-Ryul L et al.:
Stimulation of NGF production by tryptophan and its metabolites in cultured mouse astroglial cells
Brain Res.
1997
777: 228-230
|
| 21909115 |
Ehret GB et al. et al.:
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
Nature
2011
478: 103-109
|
| 22024276 |
Dohi T et al.:
Decreased circulating lipoprotein-associated phospholipase A2 levels are associated with coronary plaque regression in patients with acute coronary syndrome
Atherosclerosis
2011
219: 907-912
|
| 2782444 |
Vikenes K et al.:
Serotonin is associated with coronary artery disease and cardiac events
Circulation
1999
100: 483-489
|
| 19191108 |
Breard M et al.:
Serotonin binds to purified neuronal nitric oxide synthase: a possible explanation for ROS production induced by 5HT in the presence of nNOS
Free Radic. Res.
2009
43: 206-213
|
| 23967253 |
Fernandez C et al.:
Plasma lipid composition and risk of developing cardiovascular disease
PLoS ONE
2013
8
|
| 17454123 |
Breard M et al.:
The endogenous neurotransmitter, serotonin, modifies neuronal nitric oxide synthase activities
Free Radic. Res.
2007
41: 413-423
|
| 24170240 |
Liu H et al.:
Acute tryptophan depletion reduces nitric oxide synthase in the rat hippocampus
Neurochem. Res.
2013
38: 2595-2603
|
| 15572052 |
Fujita M et al.:
Selective blockade of serotonin 5-HT2A receptor increases coronary blood flow via augmented cardiac nitric oxide release through 5-HT1B receptor in hypoperfused canine hearts
J. Mol. Cell. Cardiol.
2004
37: 1219-1223
|
| 9205947 |
Spitsin SV et al.:
Human- and mouse-inducible nitric oxide synthase promoters require activation of phosphatidylcholine-specific phospholipase C and NF-kappa B
Mol. Med.
1997
3: 315-326
|
| 21983165 |
Dohi T et al.:
Increased circulating plasma lysophosphatidic acid in patients with acute coronary syndrome
Clin. Chim. Acta
2012
413: 207-212
|
| 9443438 |
Wever RM et al.:
Atherosclerosis and the two faces of endothelial nitric oxide synthase
Circulation
1998
1: 108-112
|
| 24444440 |
Zhang Y et al.:
Apolipoprotein B of low-density lipoprotein impairs nitric oxide-mediated endothelium-dependent relaxation in rat mesenteric arteries
Eur. J. Pharmacol.
2014
725: 10-17
|
| 22659061 |
Ferreira PF et al.:
Oxidized low-density lipoproteins and their antibodies: relationships with the reverse cholesterol transport and carotid atherosclerosis in adults without cardiovascular diseases
Clin. Chim. Acta
2012
413: 1472-1478
|
| 12372822 |
van Haperen R et al.:
Increased risk of atherosclerosis by elevated plasma levels of phospholipid transfer protein
J. Biol. Chem.
2002
277
|
| 16554055 |
Siggins S et al.:
Altered hepatic lipid status and apolipoprotein A-I metabolism in mice lacking phospholipid transfer protein
Atherosclerosis
2007
190: 114-123
|
| 20642808 |
Linkous A et al.:
Cytosolic phospholipase A2 as a mediator of disease pathogenesis
Cell. Microbiol.
2010
12: 1369-1377
|
| 10079112 |
Jiang XC et al.:
Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels
J. Clin. Invest.
1999
103: 907-914
|
| 24292666 |
Zhang Y et al.:
Protective effect of phosphatidylcholine on restoration of ethanol-injured hepatocytes related with caveolin-1
J. Membr. Biol.
2014
1: 73-80
|
| 15694928 |
Stein O et al.:
Lipid transfer proteins (LTP) and atherosclerosis
Atherosclerosis
2005
178: 217-230
|
| 19815546 |
Yea K et al.:
Lysophosphatidylcholine activates adipocyte glucose uptake and lowers blood glucose levels in murine models of diabetes
J. Biol. Chem.
2009
284
|
| 21291330 |
Kinney GL et al.:
Lipoprotein-associated phospholipase A(2) activity predicts progression of subclinical coronary atherosclerosis
Diabetes Technol. Ther.
2011
13: 381-387
|
| 14636062 |
Zhao Y et al.:
Negative charge at amino acid 149 is the molecular determinant for substrate specificity of lecithin: cholesterol acyltransferase for phosphatidylcholine containing 20-carbon sn-2 fatty acyl chains
Biochemistry
2003
42
|
| 20018880 |
Butler PL et al.:
Cross-talk between remodeling and de novo pathways maintains phospholipid balance through ubiquitination
J. Biol. Chem.
2010
285: 6246-6258
|
| 20610733 |
Riederer M et al.:
Acyl chain-dependent effect of lysophosphatidylcholine on endothelial prostacyclin production
J. Lipid Res.
2010
51: 2957-2966
|
| 11719520 |
Furbee JW Jr et al.:
Lecithin:cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice
J. Biol. Chem.
2002
277: 3511-3519
|
| 21875686 |
Tietjen I et al.:
Increased risk of coronary artery disease in Caucasians with extremely low HDL cholesterol due to mutations in ABCA1, APOA1, and LCAT
Biochim. Biophys. Acta
2012
1821: 416-424
|
| 22848500 |
Barber MN et al.:
Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes
PLoS ONE
2012
7
|
| 15721011 |
Rosenblat M et al.:
Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: a possible role for lysophosphatidylcholine
Atherosclerosis
2005
1: 69-77
|
| 12615663 |
Rozenberg O et al.:
Human serum paraoxonase 1 decreases macrophage cholesterol biosynthesis: possible role for its phospholipase-A2-like activity and lysophosphatidylcholine formation
Arterioscler. Thromb. Vasc. Biol.
2003
23: 461-467
|
| 15454271 |
Aviram M et al.:
Paraoxonases 1, 2, and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development
Free Radic. Biol. Med.
2004
37: 1304-1316
|
| 12052468 |
Yamamoto M et al.:
The expression of extracellular-superoxide dismutase is increased by lysophosphatidylcholine in human monocytic U937 cells
Atherosclerosis
2002
163: 223-228
|
| 9614091 |
Cieslik K et al.:
Transcriptional regulation of endothelial nitric-oxide synthase by lysophosphatidylcholine
J. Biol. Chem.
1998
273
|
| 7657841 |
Zembowicz A et al.:
Induction of cyclooxygenase-2 in human umbilical vein endothelial cells by lysophosphatidylcholine
J. Clin. Invest.
1995
96: 1688-1692
|
| 12814390 |
Wirleitner B et al.:
Immune activation and degradation of tryptophan in coronary heart disease
Eur. J. Clin. Invest.
2003
33: 550-554
|
| 23741477 |
Rao SP et al.:
Acyl chain-dependent effect of lysophosphatidylcholine on endothelium-dependent vasorelaxation
PLoS ONE
2013
8
|
| 23336953 |
Sulo G et al.:
Neopterin and kynurenine-tryptophan ratio as predictors of coronary events in older adults, the Hordaland Health Study
Int. J. Cardiol.
2013
168: 1435-1440
|
| 6429267 |
author information missing
Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma
J. Exp. Med.
1984
160: 310-316
|
| 6165986 |
author information missing
Induction of pulmonary indoleamine 2,3-dioxygenase by interferon
Proc. Natl. Acad. Sci. U.S.A.
1981
78: 129-132
|
| 8910295 |
Garcia-Cardena G et al.:
Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1
J. Biol. Chem.
1996
271
|
| 11028854 |
Ryborg AK et al.:
Intracutaneous injection of lysophosphatidylcholine induces skin inflammation and accumulation of leukocytes
Acta Derm. Venereol.
2000
80: 242-246
|
| 17502572 |
Lavi S et al.:
Local production of lipoprotein-associated phospholipase A2 and lysophosphatidylcholine in the coronary circulation: association with early coronary atherosclerosis and endothelial dysfunction in humans
Circulation
2007
115: 2715-2721
|
| 12809603 |
Lauber K et al.:
Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal
Cell
2003
113: 717-730
|
| 8643658 |
Moro MA et al.:
cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase
Proc. Natl. Acad. Sci. U.S.A.
1996
93: 1480-1485
|
| 8573563 |
Stone JR et al.:
Spectral and kinetic studies on the activation of soluble guanylate cyclase by nitric oxide
Biochemistry
1996
35: 1093-1099
|
| 15728511 |
Lin P et al.:
Lysophosphatidylcholine modulates neutrophil oxidant production through elevation of cyclic AMP
J. Immunol.
2005
174: 2981-2989
|
| 7955906 |
Bode-Boger SM et al.:
L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects
Clin. Sci.
1994
87: 303-310
|
| 8616947 |
Bode-Boger SM et al.:
L-arginine induces nitric oxide-dependent vasodilation in patients with critical limb ischemia. A randomized, controlled study
Circulation
1996
93: 85-90
|
| 9024155 |
Adams MR et al.:
L-arginine reduces human monocyte adhesion to vascular endothelium and endothelial expression of cell adhesion molecules
Circulation
1997
95: 662-668
|
| 19465644 |
Ponnuswamy P et al.:
Oxidative stress and compartment of gene expression determine proatherosclerotic effects of inducible nitric oxide synthase
Am. J. Pathol.
2009
174: 2400-2410
|
| 12655043 |
Lee J et al.:
Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 4843-4848
|
| 10880973 |
Malle E et al.:
Immunohistochemical evidence for the myeloperoxidase/H2O2/halide system in human atherosclerotic lesions: colocalization of myeloperoxidase and hypochlorite-modified proteins
Eur. J. Biochem.
2000
267: 4495-4503
|
| 12524231 |
Chen J et al.:
Effects of chronic treatment with L-arginine on atherosclerosis in apoE knockout and apoE/inducible NO synthase double-knockout mice
Arterioscler. Thromb. Vasc. Biol.
2003
1: 97-103
|
| 10975863 |
Detmers PA et al.:
Deficiency in inducible nitric oxide synthase results in reduced atherosclerosis in apolipoprotein E-deficient mice
J. Immunol.
2000
165: 3430-3435
|
| 9833603 |
Bode-Boger SM et al.:
L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship
Br J Clin Pharmacol
1998
46: 489-497
|
| 8900200 |
Yuan Y et al.:
The bioactive phospholipid, lysophosphatidylcholine, induces cellular effects via G-protein-dependent activation of adenylyl cyclase
J. Biol. Chem.
1996
271
|
| 23890667 |
Davids M et al.:
Plasma concentrations of arginine and asymmetric dimethylarginine do not reflect their intracellular concentrations in peripheral blood mononuclear cells
Metab. Clin. Exp.
2013
62: 1455-1461
|
| 8692835 |
Garcia-Cardena G et al.:
Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling
Proc. Natl. Acad. Sci. U.S.A.
1996
93: 6448-6453
|
| 17893196 |
Murata T et al.:
Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice
J. Exp. Med.
2007
204: 2373-2382
|
| 9325253 |
Garcia-Cardena G et al.:
Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the nos caveolin binding domain in vivo
J. Biol. Chem.
1997
272
|
| 9820828 |
Okajima F et al.:
Stimulatory and inhibitory actions of lysophosphatidylcholine, depending on its fatty acid residue, on the phospholipase C/Ca2+ system in HL-60 leukaemia cells
Biochem. J.
1998
336: 491-500
|
| 24353182 |
Cassuto J et al.:
Peroxynitrite disrupts endothelial caveolae leading to eNOS uncoupling and diminished flow-mediated dilation in coronary arterioles of diabetic patients
Diabetes
2014
63: 1381-1393
|
| 10325239 |
Vila-Petroff MG et al.:
Activation of distinct cAMP-dependent and cGMP-dependent pathways by nitric oxide in cardiac myocytes
Circ. Res.
1999
84: 1020-1031
|
| 22070693 |
Fuchs B et al.:
Lysophospholipids: potential markers of diseases and infertility? }, authors { names std { { name ml Fuchs B, affil str Institute of Medical Physics and Biophysics, University of Leipzig, Leipzig, Germany
Mini Rev Med Chem
2012
12: 74-86
|
| 21339854 |
Ford DA et al.:
Lipid oxidation by hypochlorous acid: chlorinated lipids in atherosclerosis and myocardial ischemia
Clin Lipidol
2010
5: 835-852
|
| 11238037 |
Sugiyama S et al.:
Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes
Am. J. Pathol.
2001
158: 879-891
|
| 15292228 |
Pennathur S et al.:
Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species
J. Biol. Chem.
2004
279
|
| 15314690 |
Zheng L et al.:
Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease
J. Clin. Invest.
2004
114: 529-541
|
| 14638540 |
Thukkani AK et al.:
Identification of alpha-chloro fatty aldehydes and unsaturated lysophosphatidylcholine molecular species in human atherosclerotic lesions
Circulation
2003
108: 3128-3133
|
| 15514213 |
Marsche G et al.:
2-chlorohexadecanal derived from hypochlorite-modified high-density lipoprotein-associated plasmalogen is a natural inhibitor of endothelial nitric oxide biosynthesis
Arterioscler. Thromb. Vasc. Biol.
2004
24: 2302-2306
|
| 18493808 |
Messner MC et al.:
2-Chlorohexadecanal and 2-chlorohexadecanoic acid induce COX-2 expression in human coronary artery endothelial cells
Lipids
2008
43: 581-588
|
| 22632920 |
Gungor Z et al.:
Apo E4 and lipoprotein-associated phospholipase A2 synergistically increase cardiovascular risk
Atherosclerosis
2012
223: 230-234
|
| 18703020 |
Tsubakio-Yamamoto K et al.:
Adiponectin prevents atherosclerosis by increasing cholesterol efflux from macrophages
Biochem. Biophys. Res. Commun.
2008
375: 390-394
|
| 22064597 |
Miyazaki T et al.:
m-Calpain induction in vascular endothelial cells on human and mouse atheromas and its roles in VE-cadherin disorganization and atherosclerosis
Circulation
2011
124: 2522-2532
|
| 12824289 |
Stalker TJ et al.:
A novel role for calpains in the endothelial dysfunction of hyperglycemia
FASEB J.
2003
17: 1511-1513
|
| 9580552 |
Garcia-Cardena G et al.:
Dynamic activation of endothelial nitric oxide synthase by Hsp90
Nature
1998
392: 821-824
|
| 22984960 |
Song G et al.:
SR-BI associates with ABCG1 and inhibits ABCG1-mediated cholesterol efflux from cells to high-density lipoprotein 3
Lipids Health Dis
2012
11: 118
|
| 12588762 |
Chaudhuri P et al.:
Lysophosphatidylcholine inhibits endothelial cell migration by increasing intracellular calcium and activating calpain
Arterioscler. Thromb. Vasc. Biol.
2003
23: 218-223
|
| 16456089 |
Van Eck M et al.:
Macrophage ATP-binding cassette transporter A1 overexpression inhibits atherosclerotic lesion progression in low-density lipoprotein receptor knockout mice
Arterioscler. Thromb. Vasc. Biol.
2006
26: 929-934
|
| 18057374 |
Catalano G et al.:
Cellular SR-BI and ABCA1-mediated cholesterol efflux are gender-specific in healthy subjects
J. Lipid Res.
2008
49: 635-643
|
| 20562425 |
Feng Y et al.:
Hepatocyte-specific ABCA1 transfer increases HDL cholesterol but impairs HDL function and accelerates atherosclerosis
Cardiovasc. Res.
2010
2: 376-385
|
| 21520072 |
Lin CY et al.:
Endothelin-1 exacerbates lipid accumulation by increasing the protein degradation of the ATP-binding cassette transporter G1 in macrophages
J. Cell. Physiol.
2011
226: 2198-2205
|
| 23720744 |
Tsukamoto K et al.:
Noncanonical role of the PDZ4 domain of the adaptor protein PDZK1 in the regulation of the hepatic high density lipoprotein receptor scavenger receptor class B, type I (SR-BI)
J. Biol. Chem.
2013
288
|
| 10829064 |
Ikemoto M et al.:
Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I
Proc. Natl. Acad. Sci. U.S.A.
2000
97: 6538-6543
|
| 24394674 |
Liu HY et al.:
Imbalanced response of ATP-binding cassette transporter A1 and CD36 expression to increased oxidized low-density lipoprotein loading contributes to the development of THP-1 derived foam cells
J. Biochem.
2014
155: 35-42
|
| 20075420 |
de la Llera-Moya M et al.:
The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages
Arterioscler. Thromb. Vasc. Biol.
2010
4: 796-801
|
| 9703956 |
Sawamura T et al.:
An endothelial receptor for oxidized low-density lipoprotein
Nature
1997
386: 73-77
|
| 10869259 |
Sawamura T et al.:
An endothelial receptor for oxidized low-density lipoprotein
Nature
1997
386: 73-77
|
| 19279231 |
Sawamura T et al.:
An endothelial receptor for oxidized low-density lipoprotein
Nature
1997
386: 73-77
|
| 9052782 |
Sawamura T et al.:
An endothelial receptor for oxidized low-density lipoprotein
Nature
1997
386: 73-77
|
| 9052782 |
author information missing
article information missing
|
| 16061948 |
Asztalos BF et al.:
Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux
J. Lipid Res.
2005
46: 2246-2253
|
| 12130721 |
author information missing
Denpasar Declaration on Population and Development
Integration
1994
40: 27-29
|
| 10918065 |
Wang N et al.:
Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1
J. Biol. Chem.
2000
275
|
| 11880569 |
Mardones P et al.:
Alpha-tocopherol metabolism is abnormal in scavenger receptor class B type I (SR-BI)-deficient mice
J. Nutr.
2002
132: 443-449
|
| 10777555 |
author information missing
article information missing
|
| 11433352 |
Yuhanna IS et al.:
High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase
Nat. Med.
2001
7: 853-857
|
| 12637341 |
author information missing
article information missing
|
| 24713582 |
Fruhwurth S et al.:
Inhibition of mTOR down-regulates scavenger receptor, class B, type I (SR-BI) expression, reduces endothelial cell migration and impairs nitric oxide production
Biochim. Biophys. Acta
2014
1841: 944-953
|
| 9671306 |
Mach F et al.:
Reduction of atherosclerosis in mice by inhibition of CD40 signalling
Nature
1998
394: 200-203
|
| 21130456 |
Ryoo S et al.:
OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling
Atherosclerosis
2011
214: 279-287
|
| 16339487 |
Seetharam D et al.:
High-density lipoprotein promotes endothelial cell migration and reendothelialization via scavenger receptor-B type I
Circ. Res.
2006
98: 63-72
|
| 17008605 |
Ryoo S et al.:
Oxidized low-density lipoprotein-dependent endothelial arginase II activation contributes to impaired nitric oxide signaling
Circ. Res.
2006
99: 951-960
|
| 7583580 |
Cockerill GW et al.:
High-density lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules
Arterioscler. Thromb. Vasc. Biol.
1995
15: 1987-1994
|
| 10753938 |
Uittenbogaard A et al.:
High density lipoprotein prevents oxidized low density lipoprotein-induced inhibition of endothelial nitric-oxide synthase localization and activation in caveolae
J. Biol. Chem.
2000
275
|
| 10542298 |
Blair A et al.:
Oxidized low density lipoprotein displaces endothelial nitric-oxide synthase (eNOS) from plasmalemmal caveolae and impairs eNOS activation
J. Biol. Chem.
1999
274
|
| 15838273 |
Sakurai K et al.:
Induction of endothelin-1 production in endothelial cells via co-operative action between CD40 and lectin-like oxidized LDL receptor (LOX-1)
J. Cardiovasc. Pharmacol.
2004
44: S173-S180
|
| 12504834 |
Li D et al.:
Oxidized-LDL through LOX-1 increases the expression of angiotensin converting enzyme in human coronary artery endothelial cells
Cardiovasc. Res.
2003
57: 238-243
|
| 24384558 |
Chou HC et al.:
5-Methoxytryptophan-dependent protection of cardiomyocytes from heart ischemia reperfusion injury
Arch. Biochem. Biophys.
2014
543: 15-22
|
| 22851770 |
Cheng HH et al.:
Control of cyclooxygenase-2 expression and tumorigenesis by endogenous 5-methoxytryptophan
Proc. Natl. Acad. Sci. U.S.A.
2012
109
|
| 14684629 |
Chen J et al.:
Role of caspases in Ox-LDL-induced apoptotic cascade in human coronary artery endothelial cells
Circ. Res.
2004
94: 370-376
|
| 12419941 |
Imanishi T et al.:
Oxidized low density lipoprotein potentiation of Fas-induced apoptosis through lectin-like oxidized-low density lipoprotein receptor-1 in human umbilical vascular endothelial cells
Circ. J.
2002
66: 1060-1064
|
| 17433786 |
Chen XP et al.:
Oxidized low density lipoprotein receptor-1 mediates oxidized low density lipoprotein-induced apoptosis in human umbilical vein endothelial cells: role of reactive oxygen species
Vascul. Pharmacol.
2007
47: 1-9
|
| 20203069 |
Ou HC et al.:
EGCG protects against oxidized LDL-induced endothelial dysfunction by inhibiting LOX-1-mediated signaling
J. Appl. Physiol.
2010
108: 1745-1756
|
| 23990020 |
Adlakha YK et al.:
Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRalpha expression and cholesterol homeostasis
Cell Death Dis
2013
4: e780
|
| 2443564 |
Carlin JM et al.:
Biologic-response-modifier-induced indoleamine 2,3-dioxygenase activity in human peripheral blood mononuclear cell cultures
J. Immunol.
1987
139: 2414-2418
|
| 17349013 |
Pertovaara M et al.:
Indoleamine 2,3-dioxygenase enzyme activity correlates with risk factors for atherosclerosis: the Cardiovascular Risk in Young Finns Study
Clin. Exp. Immunol.
2007
148: 106-111
|
| 18390905 |
Thum T et al.:
LOX-1 receptor blockade abrogates oxLDL-induced oxidative DNA damage and prevents activation of the transcriptional repressor Oct-1 in human coronary arterial endothelium
J. Biol. Chem.
2008
283
|
| 13678429 |
Robinson CM et al.:
Synergistic transcriptional activation of indoleamine dioxygenase by IFN-gamma and tumor necrosis factor-alpha
J. Interferon Cytokine Res.
2003
23: 413-421
|
| 16173915 |
Chen J et al.:
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) transcriptional regulation by Oct-1 in human endothelial cells: implications for atherosclerosis
Biochem. J.
2006
393: 255-265
|
| 12566375 |
Li D et al.:
LOX-1 mediates oxidized low-density lipoprotein-induced expression of matrix metalloproteinases in human coronary artery endothelial cells
Circulation
2003
107: 612-617
|
| 8663541 |
Chon SY et al.:
Cooperative role of interferon regulatory factor 1 and p91 (STAT1) response elements in interferon-gamma-inducible expression of human indoleamine 2,3-dioxygenase gene
J. Biol. Chem.
1996
271
|
| 21359968 |
Jackman KA et al.:
Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice
Naunyn Schmiedebergs Arch. Pharmacol.
2011
383: 471-481
|
| 20190767 |
Wang Y et al.:
Kynurenine is an endothelium-derived relaxing factor produced during inflammation
Nat. Med.
2010
16: 279-285
|
| 8067435 |
Williams SP et al.:
Prostaglandin I2 mediates contraction and relaxation of vascular smooth muscle
Am. J. Physiol.
1994
267: H796-H803
|
| 19932078 |
Sun J et al.:
Reactive oxygen and nitrogen species regulate inducible nitric oxide synthase function shifting the balance of nitric oxide and superoxide production
Arch. Biochem. Biophys.
2010
494: 130-137
|
| 12697739 |
Landmesser U et al.:
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension
J. Clin. Invest.
2003
111: 1201-1209
|
| 19767531 |
Yang YM et al.:
eNOS uncoupling and endothelial dysfunction in aged vessels
Am. J. Physiol. Heart Circ. Physiol.
2009
297
|
| 20375905 |
Hung MJ et al.:
Interleukin-6 inhibits endothelial nitric oxide synthase activation and increases endothelial nitric oxide synthase binding to stabilized caveolin-1 in human vascular endothelial cells
J. Hypertens.
2010
28: 940-951
|
| 7542654 |
Zembowicz A et al.:
Transcriptional induction of endothelial nitric oxide synthase type III by lysophosphatidylcholine
J. Biol. Chem.
1995
270
|
| 15265762 |
Li J et al.:
Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle
Am. J. Physiol. Endocrinol. Metab.
2004
287: E834-E841
|
| 11278602 |
Nicholson B et al.:
Sustained nitric oxide production in macrophages requires the arginine transporter CAT2
J. Biol. Chem.
2001
276
|
| 16158068 |
Gluais P et al.:
Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin
Br. J. Pharmacol.
2005
146: 834-845
|
| 8770859 |
Zeng G et al.:
Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells
J. Clin. Invest.
1996
98: 894-898
|
| 23306778 |
Muniyappa R et al.:
Role of insulin resistance in endothelial dysfunction
Rev Endocr Metab Disord
2013
14: 5-12
|
| 17666490 |
Lira VA et al.:
Nitric oxide increases GLUT4 expression and regulates AMPK signaling in skeletal muscle
Am. J. Physiol. Endocrinol. Metab.
2007
293
|
| 23863813 |
Wang H et al.:
Nitric oxide directly promotes vascular endothelial insulin transport
Diabetes
2013
62: 4030-4042
|
| 9101435 |
Chen L et al.:
Oxidative modification of low density lipoprotein in normal and hyperlipidemic patients: effect of lysophosphatidylcholine composition on vascular relaxation
J. Lipid Res.
1997
38: 546-553
|
| 7543827 |
Pritchard KA Jr et al.:
Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion
Circ. Res.
1995
77: 510-518
|
| 11004212 |
Heinloth A et al.:
Stimulation of NADPH oxidase by oxidized low-density lipoprotein induces proliferation of human vascular endothelial cells
J. Am. Soc. Nephrol.
2000
11: 1819-1825
|
| 11914250 |
Sorescu D et al.:
Superoxide production and expression of nox family proteins in human atherosclerosis
Circulation
2002
105: 1429-1435
|
| 20639222 |
Dikalova AE et al.:
Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling
Am. J. Physiol. Heart Circ. Physiol.
2010
299: H673-H679
|
| 11872373 |
Hashimoto T et al.:
Lysophosphatidylcholine inhibits the expression of prostacyclin stimulating factor in cultured vascular smooth muscle cells
J. Diabetes Complicat.
2002
16: 81-86
|
| 9498645 |
Ono Y et al.:
Effect of high glucose concentrations on prostacyclin-stimulating factor mRNA expression in cultured aortic smooth muscle cells
Diabetologia
1998
41: 134-140
|
| 11078463 |
Inoguchi T et al.:
High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells
Diabetes
2000
49: 1939-1945
|
| 23466300 |
Lee EK et al.:
Betaine attenuates lysophosphatidylcholine-mediated adhesion molecules in aged rat aorta: modulation of the nuclear factor-kappaB pathway
Exp. Gerontol.
2013
48: 517-524
|
| 14729074 |
Zhu Y et al.:
Low density lipoprotein induces eNOS translocation to membrane caveolae: the role of RhoA activation and stress fiber formation
Biochim. Biophys. Acta
2003
1635: 117-126
|
| 19135546 |
Zhou Q et al.:
High-dose lovastatin decreased basal prostacyclin production in cultured endothelial cells
Prostaglandins Other Lipid Mediat.
2009
89: 1-7
|
| 21402147 |
Crabtree MJ et al.:
Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency
Free Radic. Biol. Med.
2011
50: 1639-1646
|
| 17350631 |
Iwase M et al.:
Lysophosphatidylcholine contents in plasma LDL in patients with type 2 diabetes mellitus: relation with lipoprotein-associated phospholipase A2 and effects of simvastatin treatment
Atherosclerosis
2008
196: 931-936
|
| 14599292 |
Wei J et al.:
Peroxide-mediated chromatin remodelling of a nuclear factor kappa B site in the mouse inducible nitric oxide synthase promoter
Biochem. J.
2004
377: 809-818
|
| 15194459 |
Hattori Y et al.:
NO suppresses while peroxynitrite sustains NF-kappaB: a paradigm to rationalize cytoprotective and cytotoxic actions attributed to NO
Cardiovasc. Res.
2004
63: 31-40
|
| 15743275 |
Li C et al.:
Interaction of the endothelial nitric oxide synthase with the CAT-1 arginine transporter enhances NO release by a mechanism not involving arginine transport
Biochem. J.
2005
386: 567-574
|
| 18309100 |
Ryoo S et al.:
Endothelial arginase II: a novel target for the treatment of atherosclerosis
Circ. Res.
2008
102: 923-932
|
| 21625171 |
Dioguardi FS et al.:
To give or not to give? Lessons from the arginine paradox
J Nutrigenet Nutrigenomics
2011
4: 90-98
|
| 16723138 |
de Castro Barbosa T et al.:
Chronic oral administration of arginine induces GH gene expression and insulin resistance
Life Sci.
2006
15: 1444-1449
|
| 24914683 |
Kalogeris TJ et al.:
Adenosine prevents TNFalpha-induced decrease in endothelial mitochondrial mass via activation of eNOS-PGC-1alpha regulatory axis
PLoS ONE
2014
6
|
| 24841857 |
Qin X et al.:
Lysophosphatidylcholine perpetuates macrophage polarization toward classically activated phenotype in inflammation
Cell. Immunol.
2014
289: 185-190
|
| 21159337 |
Brocheriou I et al.:
Antagonistic regulation of macrophage phenotype by M-CSF and GM-CSF: implication in atherosclerosis
Atherosclerosis
2011
214: 316-324
|
| 25066694 |
Siu KL et al.:
Netrin-1 abrogates ischemia/reperfusion-induced cardiac mitochondrial dysfunction via nitric oxide-dependent attenuation of NOX4 activation and recoupling of NOS
|
| 19544385 |
Venardos KM et al.:
Reduced L-arginine transport contributes to the pathogenesis of myocardial ischemia-reperfusion injury
J. Cell. Biochem.
2009
108: 156-168
|
| 23011059 |
Luiking YC et al.:
Arginine de novo and nitric oxide production in disease states
Am. J. Physiol. Endocrinol. Metab.
2012
303
|
| 24929284 |
Borrell-Pages M et al.:
Cholesterol modulates LRP5 expression in the vessel wall
Atherosclerosis
2014
2: 363-370
|
| 25296984 |
Hodgkinson CP et al.:
Abi3bp regulates cardiac progenitor cell proliferation and differentiation
Circ. Res.
2014
115: 1007-1016
|
| 11739276 |
Xiao G et al.:
Inducible activation of c-Myc in adult myocardium in vivo provokes cardiac myocyte hypertrophy and reactivation of DNA synthesis
Circ. Res.
2001
89: 1122-1129
|
| 26517696 |
author information missing
Endothelial-to-mesenchymal transition drives atherosclerosis progression
J. Clin. Invest.
2015
125: 4514-4528
|
| 17442284 |
Yang HY et al.:
Transgenic overexpression of the secreted, extracellular EGF-CUB domain-containing protein SCUBE3 induces cardiac hypertrophy in mice
Cardiovasc. Res.
2007
75: 139-147
|
| 15234972 |
Wu BT et al.:
A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones
J. Biol. Chem.
2004
279
|
| 16735509 |
Williams JC et al.:
The sarcolemmal calcium pump, alpha-1 syntrophin, and neuronal nitric-oxide synthase are parts of a macromolecular protein complex
J. Biol. Chem.
2006
281
|
| 26518453 |
et al.:
|
| 22808171 |
Zill P et al.:
DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression
PLoS ONE
2012
7
|
| 26238239 |
Lupieri A et al.:
PI3K signaling in arterial diseases: Non redundant functions of the PI3K isoforms
Adv Biol Regul
2015
59: 4-18
|
| 28006775 |
Chen Q et al.:
FGF-2 Transcriptionally Down-Regulates the Expression of BNIP3L via PI3K/Akt/FoxO3a Signaling and Inhibits Necrosis and Mitochondrial Dysfunction Induced by High Concentrations of Hydrogen Peroxide in H9c2 Cells
Cell. Physiol. Biochem.
2016
40: 1678-1691
|
| 27375170 |
Hiromura M et al.:
Suppressive Effects of Glucose-Dependent Insulinotropic Polypeptide on Cardiac Hypertrophy and Fibrosis in Angiotensin II-Infused Mouse Models
Circ. J.
2016
80: 1988-1997
|
| 28135244 |
Warren HR et al. et al.:
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
Nat. Genet.
2017
49: 403-415
|
| 24510253 |
Hong SH et al.:
Impact of lysophosphatidylcholine on survival and function of UEA-1(+)acLDL (+) endothelial progenitor cells in patients with coronary artery disease
Heart Vessels
2015
30: 115-125
|
| 19689974 |
Herrmann J et al.:
Expression of lipoprotein-associated phospholipase A(2) in carotid artery plaques predicts long-term cardiac outcome
Eur. Heart J.
2009
30: 2930-2938
|
| 17105874 |
Faustino RS et al.:
RanGAP-mediated nuclear protein import in vascular smooth muscle cells is augmented by lysophosphatidylcholine
Mol. Pharmacol.
2007
71: 438-445
|
| 24865430 |
author information missing
Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis
J. Clin. Invest.
2014
124: 3187-3199
|
| 20536686 |
Dominguez-Rodriguez A et al.:
Melatonin and circadian biology in human cardiovascular disease
J. Pineal Res.
2010
49: 14-22
|
| 27129722 |
Menni C et al.:
Metabolomic profiling to dissect the role of visceral fat in cardiometabolic health
Obesity (Silver Spring)
2016
24: 1380-1388
|
| 28009916 |
Liu H et al.:
Selenium in the prevention of atherosclerosis and its underlying mechanisms
Metallomics
2017
9: 21-37
|
| 28205094 |
Li Y et al.:
Knockdown of cardiac Kir3.1 gene with siRNA can improve bradycardia in an experimental sinus bradycardia rat model
Mol. Cell. Biochem.
2017
429: 103-111
|
| 23284944 |
Bjorck HM et al.:
Characterization of shear-sensitive genes in the normal rat aorta identifies Hand2 as a major flow-responsive transcription factor
PLoS ONE
2012
7
|
| 25883568 |
Chen L et al.:
Recent advances in circadian rhythms in cardiovascular system
Front Pharmacol
2015
6: 71
|
| 25702058 |
Kjolby M et al.:
Sortilin, encoded by the cardiovascular risk gene SORT1, and its suggested functions in cardiovascular disease
Curr Atheroscler Rep
2015
17: 496
|
| 23283348 |
Carlo AS et al.:
The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-beta peptide in the brain
J. Neurosci.
2013
33: 358-370
|
| 23114023 |
Chang MK et al.:
The pro-atherogenic effects of macrophages are reduced upon formation of a complex between C-reactive protein and lysophosphatidylcholine
J Inflamm (Lond)
2012
1: 42
|
| 19809313 |
Lattka E et al.:
Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism
Curr. Opin. Lipidol.
2010
21: 64-69
|
| 26452419 |
Chung HK et al.:
Plasma phospholipid arachidonic acid and lignoceric acid are associated with the risk of cardioembolic stroke
Nutr Res
2015
35: 1001-1008
|
| 27171899 |
Deeb RS et al.:
Repair Mechanisms in Oxidant-Driven Chronic Inflammatory Disease
Am. J. Pathol.
2016
186: 1736-1749
|
| 28372564 |
Feng X et al.:
Low apoA-I is associated with insulin resistance in patients with impaired glucose tolerance: a cross-sectional study
Lipids Health Dis
2017
16: 69
|
| 25074463 |
Voisin S et al.:
Dietary fat quality impacts genome-wide DNA methylation patterns in a cross-sectional study of Greek preadolescents
Eur. J. Hum. Genet.
2015
23: 654-662
|
| 25067958 |
Pownall HJ et al.:
Setting the course for apoAII: a port in sight? }, authors { names std { { name ml Pownall HJ, affil str Houston Methodist Research Institute, 6670 Bertner Avenue, Houston, TX 77030, USA
Clin Lipidol
2013
8: 551-560
|
| 28450971 |
Tremblay BL et al.:
Epigenetic changes in blood leukocytes following an omega-3 fatty acid supplementation
Clin Epigenetics
2017
9: 43
|
| 21985788 |
Faul C et al.:
FGF23 induces left ventricular hypertrophy
J. Clin. Invest.
2011
121: 4393-4408
|
| 26971351 |
Alam U et al.:
Vitamin D and Diabetic Complications: True or False Prophet? }, authors { names std { { name ml Alam U, affil str Centre for Endocrinology and Diabetes, Institute of Human Development, University of Manchester and the Manchester Royal Infirmary, Central Manchester Hospital Foundation Trust, Manchester, UK. uazman.alam@manchester.ac.uk
Diabetes Ther
2016
7: 11-26
|
| 22021094 |
Lau SL et al.:
Interferons induce the expression of IFITM1 and IFITM3 and suppress the proliferation of rat neonatal cardiomyocytes
J. Cell. Biochem.
2012
113: 841-847
|
| 1526278 |
Ponzoni M et al.:
Stimulation of receptor-coupled phospholipase A2 by interferon-gamma
FEBS Lett.
1992
310: 17-21
|
| 9186631 |
Nishi E et al.:
Lysophosphatidylcholine induces heparin-binding epidermal growth factor-like growth factor and interferon-gamma in human T-lymphocytes
Ann. N. Y. Acad. Sci.
1997
811: 519-524
|
| 24603679 |
Popson SA et al.:
Interferon-induced transmembrane protein 1 regulates endothelial lumen formation during angiogenesis
Arterioscler. Thromb. Vasc. Biol.
2014
34: 1011-1019
|
| 23601107 |
Amini-Bavil-Olyaee S et al.:
The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry
Cell Host Microbe
2013
13: 452-464
|
| 26846866 |
Raman K et al.:
Peripheral Blood MCEMP1 Gene Expression as a Biomarker for Stroke Prognosis
Stroke
2016
47: 652-658
|
| 24558110 |
Hoogeveen RC et al.:
Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study
Arterioscler. Thromb. Vasc. Biol.
2014
34: 1069-1077
|
| 24548633 |
Liu T et al.:
Mitochondrial proteome remodeling in ischemic heart failure
Life Sci.
2014
101: 27-36
|
| 28502328 |
Lv Y et al.:
The Association Between Endocan Levels and Subclinical Atherosclerosis in Patients With Type 2 Diabetes Mellitus
Am. J. Med. Sci.
2017
353: 433-438
|
| 19076828 |
Jylhava J et al.:
Genetics of C-reactive protein and complement factor H have an epistatic effect on carotid artery compliance: the Cardiovascular Risk in Young Finns Study
Clin. Exp. Immunol.
2009
155: 53-58
|
| 20519495 |
Kavran JM et al.:
All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner
J. Biol. Chem.
2010
285
|
| 28546218 |
Li F et al.:
ADAMTS5 Deficiency in Calcified Aortic Valves Is Associated With Elevated Pro-Osteogenic Activity in Valvular Interstitial Cells
Arterioscler. Thromb. Vasc. Biol.
2017
37: 1339-1351
|
| 25196463 |
Werner P et al.:
Mutations in NTRK3 suggest a novel signaling pathway in human congenital heart disease
Hum. Mutat.
2014
35: 1459-1468
|
| 25725476 |
di Salvo TG et al.:
Right ventricular myocardial biomarkers in human heart failure
J. Card. Fail.
2015
21: 398-411
|
| 25145866 |
Gluba-Brzozka A et al.:
Markers of increased cardiovascular risk in patients with chronic kidney disease
Lipids Health Dis
2014
13: 135
|
| 23527250 |
Chen K et al.:
AMP activated protein kinase is indispensable for myocardial adaptation to caloric restriction in mice
PLoS ONE
2013
3
|
| 25775556 |
Denes A et al.:
AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3
Proc. Natl. Acad. Sci. U.S.A.
2015
112: 4050-4055
|
| 28585906 |
Gruson D et al.:
Elevation of plasma oncostatin M in heart failure
Future Cardiol
2017
13: 219-227
|
| 28471981 |
Xie J et al.:
Oncostatin M was associated with thrombosis in patients with atrial fibrillation
Medicine (Baltimore)
2017
96: e6806
|
| 27573291 |
Gupta MK et al.:
Making the connections: Autophagy and post-translational modifications in cardiomyocytes
Autophagy
2016
12: 2252-2253
|
| 28290476 |
Shimojima M et al.:
Emerin plays a crucial role in nuclear invagination and in the nuclear calcium transient
Sci Rep
2017
7: 44312
|
| 21625439 |
Dobo J et al.:
Cleavage of kininogen and subsequent bradykinin release by the complement component: mannose-binding lectin-associated serine protease (MASP)-1
PLoS ONE
2011
6
|
| 19689262 |
Bryant JW et al.:
Human plasma kallikrein-kinin system: physiological and biochemical parameters
Cardiovasc Hematol Agents Med Chem
2009
7: 234-250
|
| 9615225 |
Zazzi H et al.:
Structure and transcription regulation of the human insulin-like growth factor binding protein 4 gene (IGFBP4)
Genomics
1998
49: 401-410
|
| 24548188 |
Urbonaviciene G et al.:
IGF-I and IGFBP2 in peripheral artery disease: results of a prospective study
Scand. Cardiovasc. J.
2014
48: 99-105
|
| 25970343 |
Larsen SB et al.:
Calprotectin and platelet aggregation in patients with stable coronary artery disease
PLoS ONE
2015
5
|
| 19330902 |
Zhao W et al.:
Gender-specific association between the kininogen 1 gene variants and essential hypertension in Chinese Han population
J. Hypertens.
2009
27: 484-490
|
| 12186797 |
Juul A et al.:
Low serum insulin-like growth factor I is associated with increased risk of ischemic heart disease: a population-based case-control study
Circulation
2002
106: 939-944
|
| 28125622 |
Shah RD et al.:
Expression of Calgranulin Genes S100A8, S100A9 and S100A12 Is Modulated by n-3 PUFA during Inflammation in Adipose Tissue and Mononuclear Cells
PLoS ONE
2017
12
|
| 20379055 |
Yamagishi K et al.:
Coagulation factors II, V, IX, X, XI, and XII, plasminogen, and alpha-2 antiplasmin and risk of coronary heart disease
J. Atheroscler. Thromb.
2010
17: 402-409
|
| 28392446 |
Tan X et al.:
The asymmetric dimethylarginine-mediated inhibition of nitric oxide in the rostral ventrolateral medulla contributes to regulation of blood pressure in hypertensive rats
Nitric Oxide
2017
67: 58-67
|
| 25963357 |
Li H et al.:
Serum hepcidin predicts uremic accelerated atherosclerosis in chronic hemodialysis patients with diabetic nephropathy
Chin. Med. J.
2015
128: 1351-1357
|
| 27897970 |
Lakhal-Littleton S et al.:
An essential cell-autonomous role for hepcidin in cardiac iron homeostasis
|
| 24578379 |
Huang J et al.:
Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2
Arterioscler. Thromb. Vasc. Biol.
2014
34: 1093-1101
|
| 24764453 |
Uhl B et al. et al.:
Tissue plasminogen activator promotes postischemic neutrophil recruitment via its proteolytic and nonproteolytic properties
Arterioscler Thromb Vasc Biol
2014
34: 1495-1504
|
| 28462074 |
Cady G et al.:
Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons
Mol Metab
2017
6: 393-405
|
| 9501082 |
Sasaki T et al.:
Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin
EMBO J.
1998
17: 1606-1613
|
| 25902191 |
Baban B et al.:
Upregulation of Programmed Death-1 and Its Ligand in Cardiac Injury Models: Interaction with GADD153
PLoS ONE
2015
10
|
| 2496749 |
Boose JA et al.:
The single-chain form of tissue-type plasminogen activator has catalytic activity: studies with a mutant enzyme that lacks the cleavage site
Biochemistry
1989
28: 635-643
|
| 16844696 |
Sullivan MM et al.:
Matricellular hevin regulates decorin production and collagen assembly
J. Biol. Chem.
2006
281
|
| 22411972 |
Mulligan CM et al.:
Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart
Cardiovasc. Res.
2012
94: 460-468
|
| 28319050 |
author information missing
Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques
J. Clin. Invest.
2017
127: 1546-1560
|
| 23788672 |
Zheng Y et al.:
Associations between metabolomic compounds and incident heart failure among African Americans: the ARIC Study
Am. J. Epidemiol.
2013
178: 534-542
|
| 28293020 |
Pallister T et al.:
Untangling the relationship between diet and visceral fat mass through blood metabolomics and gut microbiome profiling
Int J Obes (Lond)
2017
41: 1106-1113
|
| 27581838 |
Dullaart RP et al.:
Plasma phospholipid transfer protein activity is inversely associated with betaine in diabetic and non-diabetic subjects
Lipids Health Dis
2016
15: 143
|
| 28356272 |
Roe AJ et al.:
Choline and its metabolites are differently associated with cardiometabolic risk factors, history of cardiovascular disease, and MRI-documented cerebrovascular disease in older adults
Am. J. Clin. Nutr.
2017
105: 1283-1290
|
| 24795654 |
Kempson SA et al.:
The betaine/GABA transporter and betaine: roles in brain, kidney, and liver
Front Physiol
2014
5: 159
|
| 27872611 |
Connolly ML et al.:
Hypocholesterolemic and Prebiotic Effects of a Whole-Grain Oat-Based Granola Breakfast Cereal in a Cardio-Metabolic At Risk Population
Front Microbiol
2016
7: 1675
|
| 19337540 |
Chen J et al.:
Beta-glucans in the treatment of diabetes and associated cardiovascular risks
Vasc Health Risk Manag
2008
4: 1265-1272
|
| 16015250 |
Biorklund M et al.:
Changes in serum lipids and postprandial glucose and insulin concentrations after consumption of beverages with beta-glucans from oats or barley: a randomised dose-controlled trial
Eur J Clin Nutr
2005
59: 1272-1281
|
| 23615880 |
Wang W et al.:
Glycine metabolism in animals and humans: implications for nutrition and health
Amino Acids
2013
45: 463-477
|
| 29044182 |
Casieri V et al.:
Long-term Intake of Pasta Containing Barley (1-3)Beta-D-Glucan Increases Neovascularization-mediated Cardioprotection through Endothelial Upregulation of Vascular Endothelial Growth Factor and Parkin
Sci Rep
2017
7: 13424
|
| 24015188 |
Borja MS et al. et al.:
HDL-apoA-I exchange: rapid detection and association with atherosclerosis
PLoS ONE
2013
8
|
| 27164079 |
Pisano G et al.:
Vascular Damage in Patients with Nonalcoholic Fatty Liver Disease: Possible Role of Iron and Ferritin
|
| 19821111 |
et al.:
Molecular bases of copper and iron deficiency-associated dyslipidemia: a microarray analysis of the rat intestinal transcriptome
Genes Nutr
2010
5: 1-8
|
| 29506183 |
Loo RL et al.:
Characterization of metabolic responses to healthy diets and association with blood pressure: application to the Optimal Macronutrient Intake Trial for Heart Health (OmniHeart), a randomized controlled study
Am. J. Clin. Nutr.
2018
107: 323-334
|
| 29167659 |
Lyu M et al.:
Balancing Herbal Medicine and Functional Food for Prevention and Treatment of Cardiometabolic Diseases through Modulating Gut Microbiota
Front Microbiol
2017
8: 2146
|
| 27049134 |
Bost M et al.:
Dietary copper and human health: Current evidence and unresolved issues
J Trace Elem Med Biol
2016
35: 107-115
|
| 29725935 |
Wang Z et al.:
Gut microbiota derived metabolites in cardiovascular health and disease
|
| 15486091 |
Khan SA et al.:
Neuronal nitric oxide synthase negatively regulates xanthine oxidoreductase inhibition of cardiac excitation-contraction coupling
Proc. Natl. Acad. Sci. U.S.A.
2004
101
|
| 30533416 |
Tintut Y et al.:
Lipoproteins in Cardiovascular Calcification: Potential Targets and Challenges
Front Cardiovasc Med
2018
5: 172
|
| 22995898 |
Albright RA et al.:
NPP4 is a procoagulant enzyme on the surface of vascular endothelium
Blood
2012
120: 4432-4440
|
| 29568240 |
Niijima S et al.:
Differential impact of diabetes mellitus on antiplatelet effects of prasugrel and clopidogrel
Thromb J
2018
16: 5
|
| 19342597 |
Chava KR et al.:
CREB-mediated IL-6 expression is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration
Arterioscler. Thromb. Vasc. Biol.
2009
29: 809-815
|
| 11756171 |
Jin J et al.:
Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors
Blood
2002
99: 193-198
|
| 30310470 |
Kikas P et al.:
Cardiovascular Implications of Sphingomyelin Presence in Biological Membranes
Eur Cardiol
2018
13: 42-45
|
| 27224553 |
Piek A et al.:
HE4 Serum Levels Are Associated with Heart Failure Severity in Patients With Chronic Heart Failure
J. Card. Fail.
2017
23: 12-19
|
| 29247129 |
Foulquier S et al.:
WNT Signaling in Cardiac and Vascular Disease
Pharmacol. Rev.
2018
70: 68-141
|
| 29167565 |
Alcala M et al.:
Increased inflammation, oxidative stress and mitochondrial respiration in brown adipose tissue from obese mice
Sci Rep
2017
7: 16082
|
| 28194159 |
Flouris AD et al.:
Role of UCP1 Gene Variants in Interethnic Differences in the Development of Cardio-Metabolic Diseases
Front Genet
2017
8: 7
|
| 30393491 |
Totomoch-Serra A et al.:
Association of common polymorphisms in the VEGFA and SIRT1 genes with type 2 diabetes-related traits in Mexicans
Arch Med Sci
2018
14: 1361-1373
|
| 20443916 |
Calalb MB et al.:
Increased phosphorylation-dependent nuclear export of class II histone deacetylases in failing human heart
Clin Transl Sci
2009
2: 325-332
|
| 26764138 |
Greissel A et al.:
Histone acetylation and methylation significantly change with severity of atherosclerosis in human carotid plaques
Cardiovasc. Pathol.
2016
25: 79-86
|
| 26819317 |
Ariffin JK et al.:
The E3 ubiquitin ligase RNF144B is LPS-inducible in human, but not mouse, macrophages and promotes inducible IL-1beta expression
J. Leukoc. Biol.
2016
100: 155-161
|
| 30377171 |
Kulkarni SS et al.:
WDR5 regulates left-right patterning via chromatin-dependent and -independent functions
|
| 23146621 |
Carillo BA et al.:
Changes in GABAergic inputs in the paraventricular nucleus maintain sympathetic vasomotor tone in chronic heart failure
Auton Neurosci
2012
171: 41-48
|
| 29852387 |
Qin L et al.:
MicroRNA-497 promotes proliferation and inhibits apoptosis of cardiomyocytes through the downregulation of Mfn2 in a mouse model of myocardial ischemia-reperfusion injury
Biomed. Pharmacother.
2018
105: 103-114
|
| 24905188 |
Givvimani S et al.:
Dysregulation of Mfn2 and Drp-1 proteins in heart failure
Can. J. Physiol. Pharmacol.
2014
92: 583-591
|
| 28057766 |
Steffen J et al.:
Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria
Mol. Biol. Cell
2017
28: 600-612
|
| 28917245 |
Piao W et al.:
A single-nucleotide polymorphism in transferrin is associated with soluble transferrin receptor in Chinese adolescents
Asia Pac J Clin Nutr
2017
26: 1170-1178
|
| 19084217 |
Benyamin B et al.:
Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels
Am. J. Hum. Genet.
2009
84: 60-65
|
| 28157227 |
Perretta-Tejedor N et al.:
Association of VAV2 and VAV3 polymorphisms with cardiovascular risk factors
Sci Rep
2017
7: 41875
|
| 17202406 |
Sauzeau V et al.:
Loss of Vav2 proto-oncogene causes tachycardia and cardiovascular disease in mice
Mol. Biol. Cell
2007
18: 943-952
|
| 12054757 |
Chen J et al.:
A novel gene IC53 stimulates ECV304 cell proliferation and is upregulated in failing heart
Biochem. Biophys. Res. Commun.
2002
294: 161-166
|
| 20516643 |
Zhou J et al. et al.:
GSK-3alpha directly regulates beta-adrenergic signaling and the response of the heart to hemodynamic stress in mice
J. Clin. Invest.
2010
120: 2280-2291
|
| 24786827 |
Huang CY et al.:
ANG II promotes IGF-IIR expression and cardiomyocyte apoptosis by inhibiting HSF1 via JNK activation and SIRT1 degradation
Cell Death Differ.
2014
21: 1262-1274
|
| 27259994 |
Bai B et al.:
Endothelial SIRT1 prevents adverse arterial remodeling by facilitating HERC2-mediated degradation of acetylated LKB1
Oncotarget
2016
7
|
| 30192743 |
Yamac AH et al.:
MicroRNA 199a Is Downregulated in Patients After Coronary Artery Bypass Graft Surgery and Is Associated with Increased Levels of Sirtuin 1 (SIRT 1) Protein and Major Adverse Cardiovascular Events at 3-Year Follow-Up
Med. Sci. Monit.
2018
24: 6245-6254
|
| 28191886 |
Vikram A et al. et al.:
Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel
Nat. Med.
2017
23: 361-367
|
| 30726893 |
Brooks DL et al.:
Aldosterone Modulates the Mechanistic Target of Rapamycin Signaling in Male Mice
Endocrinology
2019
160: 716-728
|
| 30342030 |
Lu Y et al.:
Resveratrol attenuates high fat diet-induced mouse cardiomyopathy through upregulation of estrogen related receptor-alpha
Eur. J. Pharmacol.
2019
843: 88-95
|
| 22967852 |
Li Y et al.:
Prospective study of restless legs syndrome and coronary heart disease among women
Circulation
2012
126: 1689-1694
|
| 23871353 |
Shen T et al. et al.:
Tbx20 functions as an important regulator of estrogen-mediated cardiomyocyte protection during oxidative stress
Int. J. Cardiol.
2013
168: 3704-3714
|
| 30597731 |
Li S et al.:
RING finger protein 10 attenuates vascular restenosis by inhibiting vascular smooth muscle cell hyperproliferation in vivo and vitro
|
| 29723537 |
Yu G et al.:
RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo
Life Sci.
2018
208: 325-332
|
| 27033308 |
Wang H et al.:
miR-21-3p controls sepsis-associated cardiac dysfunction via regulating SORBS2
J. Mol. Cell. Cardiol.
2016
94: 43-53
|
| 12356727 |
Nicod M et al.:
A novel vasopressin-induced transcript promotes MAP kinase activation and ENaC downregulation
EMBO J.
2002
21: 5109-5117
|
| 24770418 |
Li X et al.:
Molecular and cellular roles of PI31 (PSMF1) protein in regulation of proteasome function
J. Biol. Chem.
2014
289
|
| 29285671 |
Tseng CCS et al.:
The Interleukin-33/ST2 Pathway Is Expressed in the Failing Human Heart and Associated with Pro-fibrotic Remodeling of the Myocardium
J Cardiovasc Transl Res
2018
11: 15-21
|
| 16335786 |
Lin J et al.:
Characterization of Mesenchyme Homeobox 2 (MEOX2) transcription factor binding to RING finger protein 10
Mol. Cell. Biochem.
2005
275: 75-84
|
| 24667923 |
Lassner D et al.:
Improved diagnosis of idiopathic giant cell myocarditis and cardiac sarcoidosis by myocardial gene expression profiling
Eur. Heart J.
2014
35: 2186-2195
|
| 23532846 |
Josekutty J et al.:
Microsomal triglyceride transfer protein inhibition induces endoplasmic reticulum stress and increases gene transcription via Ire1alpha/cJun to enhance plasma ALT/AST
J. Biol. Chem.
2013
288
|
| 28209402 |
Nayak A et al. et al.:
Chemokine receptor patterns and right heart failure in mechanical circulatory support
J. Heart Lung Transplant.
2017
36: 657-665
|
| 27902985 |
Almanzar G et al. et al.:
Disease Manifestation and Inflammatory Activity as Modulators of Th17/Treg Balance and RORC/FoxP3 Methylation in Systemic Sclerosis
Int. Arch. Allergy Immunol.
2016
171: 141-154
|
| 30240284 |
Fu K et al.:
A temporal transcriptome and methylome in human embryonic stem cell-derived cardiomyocytes identifies novel regulators of early cardiac development
Epigenetics
2018
13: 1013-1026
|
| 16261285 |
Ostojic P et al.:
Different clinical features in patients with limited and diffuse cutaneous systemic sclerosis
Clin. Rheumatol.
2006
25: 453-457
|
| 9211900 |
Wang B et al.:
ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks
J. Biol. Chem.
1997
272
|
| 25217591 |
Wales S et al.:
Global MEF2 target gene analysis in cardiac and skeletal muscle reveals novel regulation of DUSP6 by p38MAPK-MEF2 signaling
Nucleic Acids Res.
2014
42
|
| 15140762 |
Thomas CP et al.:
AVP-induced VIT32 gene expression in collecting duct cells occurs via trans-activation of a CRE in the 5-flanking region of the VIT32 gene
Am. J. Physiol. Renal Physiol.
2004
287: F460-F468
|
| 21041950 |
Denzel MS et al.:
T-cadherin is critical for adiponectin-mediated cardioprotection in mice
J. Clin. Invest.
2010
120: 4342-4352
|
| 23824191 |
Parker-Duffen JL et al.:
T-cadherin is essential for adiponectin-mediated revascularization
J. Biol. Chem.
2013
288
|
| 30323296 |
Wang C et al.:
PARP1 promote autophagy in cardiomyocytes via modulating FoxO3a transcription
Cell Death Dis
2018
9: 1047
|
| 16952979 |
Ni YG et al. et al.:
Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling
Circulation
2006
114: 1159-1168
|
| 28432149 |
Borg N et al.:
CD73 on T Cells Orchestrates Cardiac Wound Healing After Myocardial Infarction by Purinergic Metabolic Reprogramming
Circulation
2017
136: 297-313
|
| 16280269 |
Peter I et al.:
Association of estrogen receptor beta gene polymorphisms with left ventricular mass and wall thickness in women
Am. J. Hypertens.
2005
18: 1388-1395
|
| 18931023 |
Ricchiuti V et al.:
Estradiol increases angiotensin II type 1 receptor in hearts of ovariectomized rats
J. Endocrinol.
2009
200: 75-84
|
| 28219978 |
Stallmeyer B et al. et al.:
A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction
Circ. Res.
2017
120: e33-e44
|
| 29084269 |
Ridge LA et al. et al.:
Non-muscle myosin IIB (Myh10) is required for epicardial function and coronary vessel formation during mammalian development
PLoS Genet.
2017
13
|
| 28687623 |
Ma X et al.:
Nonmuscle myosin IIB regulates epicardial integrity and epicardium-derived mesenchymal cell maturation
J. Cell. Sci.
2017
130: 2696-2706
|
| 24825879 |
Ma X et al.:
A point mutation in Myh10 causes major defects in heart development and body wall closure
Circ Cardiovasc Genet
2014
7: 257-265
|
| 20562446 |
Wang L et al.:
A comprehensive genetic study on left atrium size in Caribbean Hispanics identifies potential candidate genes in 17p10
Circ Cardiovasc Genet
2010
3: 386-392
|
| 18263591 |
Antonson P et al.:
RAP250 is a coactivator in the transforming growth factor beta signaling pathway that interacts with Smad2 and Smad3
J. Biol. Chem.
2008
283: 8995-9001
|
| 12368298 |
Kuang SQ et al.:
Deletion of the cancer-amplified coactivator AIB3 results in defective placentation and embryonic lethality
J. Biol. Chem.
2002
277
|
| 29443552 |
Jesus ICG et al.:
Alamandine acts via MrgD to induce AMPK/NO activation against ANG II hypertrophy in cardiomyocytes
Am. J. Physiol.
2018
314: C702-C711
|
| 23446738 |
Lautner RQ et al. et al.:
Discovery and characterization of alamandine: a novel component of the renin-angiotensin system
Circ. Res.
2013
112: 1104-1111
|
| 25813860 |
Parikh A et al.:
Signaling Pathways and Gene Regulatory Networks in Cardiomyocyte Differentiation
Tissue Eng Part B Rev
2015
21: 377-392
|
| 29564519 |
Li D et al.:
Planar Cell Polarity Signaling in Mammalian Cardiac Morphogenesis
Pediatr Cardiol
2018
39: 1052-1062
|
| 28159874 |
Klena NT et al.:
Cilia and Ciliopathies in Congenital Heart Disease
|
| 26386426 |
Basheer WA et al.:
Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis
J. Mol. Cell. Cardiol.
2015
88: 1-13
|
| 30143604 |
Emperador-Melero J et al.:
Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi
Nat Commun
2018
9: 3421
|
| 26959817 |
Gao Y et al.:
Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats
PLoS ONE
2016
11
|
| 27720608 |
Lin Z et al. et al.:
Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth
Dev. Cell
2016
39: 466-479
|
| 30789911 |
Yu W et al. et al.:
VGLL4 plays a critical role in heart valve development and homeostasis
PLoS Genet.
2019
15
|
| 18162545 |
Lee MJ et al.:
Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway
Proc Natl Acad Sci U S A
2008
105: 100-105
|
| 23824717 |
Nakaya T et al.:
p600 Plays Essential Roles in Fetal Development
PLoS One
2013
8
|
| 29317337 |
Vasavan T et al.:
Heart and bile acids - Clinical consequences of altered bile acid metabolism
Biochim Biophys Acta Mol Basis Dis
2018
1864: 1345-1355
|
| 19156209 |
Nath AK et al.:
Proteomic-based detection of a protein cluster dysregulated during cardiovascular development identifies biomarkers of congenital heart defects
PLoS ONE
2009
4: e4221
|
| 24134842 |
Luo T et al.:
Uhrf2 is important for DNA damage response in vascular smooth muscle cells
Biochem. Biophys. Res. Commun.
2013
441: 65-70
|
| 17725325 |
Yamakawa T et al.:
Interaction of syntaxin 1A with the N-terminus of Kv4.2 modulates channel surface expression and gating
Biochemistry
2007
46
|
| 16672225 |
Kang Y et al.:
Syntaxin-1A actions on sulfonylurea receptor 2A can block acidic pH-induced cardiac K(ATP) channel activation
J. Biol. Chem.
2006
281
|
| 19039652 |
Das P et al.:
Upregulation of myocardial syntaxin1A is associated with an early stage of polymicrobial sepsis
Mol. Cell. Biochem.
2009
323: 61-68
|
| 27798760 |
Levitan BM et al.:
Rad-deletion Phenocopies Tonic Sympathetic Stimulation of the Heart
J Cardiovasc Transl Res
2016
9: 432-444
|
| 18056528 |
Chang L et al. et al.:
Rad GTPase deficiency leads to cardiac hypertrophy
Circulation
2007
116: 2976-2983
|
| 12209018 |
Lynch RA et al.:
Novel and nondetected human signaling protein polymorphisms
Physiol. Genomics
2002
10: 159-168
|
| 30391675 |
Wei Z et al.:
Pan-senescence transcriptome analysis identified RRAD as a marker and negative regulator of cellular senescence
Free Radic. Biol. Med.
2019
130: 267-277
|
| 25193703 |
Yamakawa H et al.:
Suppression of Rad leads to arrhythmogenesis via PKA-mediated phosphorylation of ryanodine receptor activity in the heart
Biochem. Biophys. Res. Commun.
2014
452: 701-707
|
| 24334906 |
Manning JR et al.:
Rad GTPase deletion increases L-type calcium channel current leading to increased cardiac contraction
J Am Heart Assoc
2013
2
|
| 17525370 |
Yada H et al.:
Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart
Circ. Res.
2007
101: 69-77
|
| 19638298 |
Porterfield VM et al.:
Temporal patterns of light-induced immediate-early gene expression in the suprachiasmatic nucleus
Neurosci. Lett.
2009
463: 70-73
|
| 28732776 |
Withers CN et al.:
Rad GTPase is essential for the regulation of bone density and bone marrow adipose tissue in mice
Bone
2017
103: 270-280
|
| 23185005 |
Gopalakrishnan K et al.:
Targeted disruption of Adamts16 gene in a rat genetic model of hypertension
Proc. Natl. Acad. Sci. U.S.A.
2012
109
|
| 16687132 |
Lin L et al.:
Isl1 is upstream of sonic hedgehog in a pathway required for cardiac morphogenesis
Dev. Biol.
2006
295: 756-763
|
| 30446837 |
Moore JB 4th et al.:
Epigenetically modified cardiac mesenchymal stromal cells limit myocardial fibrosis and promote functional recovery in a model of chronic ischemic cardiomyopathy
Basic Res. Cardiol.
2018
114: 3
|
| 22234868 |
Bos JM et al.:
TGFbeta-inducible early gene-1 (TIEG1) mutations in hypertrophic cardiomyopathy
J. Cell. Biochem.
2012
113: 1896-1903
|
| 24126098 |
Kuwahara K et al.:
Role of NRSF/REST in the regulation of cardiac gene expression and function
Circ. J.
2013
77: 2682-2686
|
| 14633990 |
Kuwahara K et al. et al.:
NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function
EMBO J.
2003
22: 6310-6321
|
| 20089851 |
Tanno M et al.:
Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure
J. Biol. Chem.
2010
285: 8375-8382
|
| 16155214 |
Cooper AF et al.:
Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused
Development
2005
132: 4407-4417
|
| 28993153 |
Pan B et al.:
TFEB activation protects against cardiac proteotoxicity via increasing autophagic flux
J. Mol. Cell. Cardiol.
2017
113: 51-62
|
| 24282237 |
Lin MJ et al.:
Massive palmitoylation-dependent endocytosis during reoxygenation of anoxic cardiac muscle
Elife
2013
2
|
| 30241943 |
Mao YY et al.:
Circ-SATB2 upregulates STIM1 expression and regulates vascular smooth muscle cell proliferation and differentiation through miR-939
Biochem. Biophys. Res. Commun.
2018
505: 119-125
|
| 29263819 |
Mak CCY et al. et al.:
De novo large rare copy-number variations contribute to conotruncal heart disease in Chinese patients
NPJ Genom Med
2016
1: 16033
|
| 29043394 |
Li B et al.:
In Silico Analyses Reveal the Relationship Between SIX1/EYA1 Mutations and Conotruncal Heart Defects
Pediatr Cardiol
2018
39: 176-182
|
| 27693370 |
Huang RT et al. et al.:
CASZ1 loss-of-function mutation associated with congenital heart disease
Gene
2016
595: 62-68
|
| 25953344 |
Dorr KM et al.:
Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development
Development
2015
142: 2037-2047
|
| 25190801 |
Liu Z et al.:
Essential role of the zinc finger transcription factor Casz1 for mammalian cardiac morphogenesis and development
J. Biol. Chem.
2014
289
|
| 16631614 |
Liu Z et al.:
Molecular cloning and characterization of human Castor, a novel human gene upregulated during cell differentiation
Biochem. Biophys. Res. Commun.
2006
344: 834-844
|
| 26296975 |
Liu Z et al.:
Zinc finger transcription factor CASZ1 interacts with histones, DNA repair proteins and recruits NuRD complex to regulate gene transcription
Oncotarget
2015
6
|
| 28693373 |
Chen PY et al.:
Prenatal Growth Patterns and Birthweight Are Associated With Differential DNA Methylation and Gene Expression of Cardiometabolic Risk Genes in Human Placentas: A Discovery-Based Approach
Reprod Sci
2018
25: 523-539
|
| 26547215 |
Re A et al. et al.:
Anacardic acid and thyroid hormone enhance cardiomyocytes production from undifferentiated mouse ES cells along functionally distinct pathways
Endocrine
2016
53: 681-688
|
| 22449847 |
McCulley DJ et al.:
Transcription factor pathways and congenital heart disease
Curr Top Dev Biol
2012
100: 253-277
|
| 28541494 |
Patel RS et al.:
Understanding the role of genetics in hypertension
Eur. Heart J.
2017
38: 2309-2312
|
| 21461576 |
Zhu C et al.:
Screening for differential methylation status in fetal myocardial tissue samples with ventricular septal defects by promoter methylation microarrays
Mol Med Rep
2011
4: 137-143
|
| 26876120 |
Azhar M et al.:
Genetic and Developmental Basis of Cardiovascular Malformations
Clin Perinatol
2016
43: 39-53
|
| 22885181 |
Shan J et al.:
Genetic analysis of the SIRT1 gene promoter in ventricular septal defects
Biochem. Biophys. Res. Commun.
2012
425: 741-745
|
| 17098745 |
Kume S et al.:
SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation
J. Biol. Chem.
2007
282: 151-158
|
| 21269274 |
Yan X et al.:
Smad7: not only a regulator, but also a cross-talk mediator of TGF-beta signalling
Biochem. J.
2011
434: 1-10
|
| 25180292 |
Zerr P et al.:
Sirt1 regulates canonical TGF-beta signalling to control fibroblast activation and tissue fibrosis
Ann. Rheum. Dis.
2016
75: 226-233
|
| 29615572 |
Wiegering A et al.:
The Role of Hedgehog Signalling in the Formation of the Ventricular Septum
|
| 24345806 |
Koefoed K et al.:
Cilia and coordination of signaling networks during heart development
Organogenesis
2014
10: 108-125
|
| 21550985 |
Susan-Resiga D et al.:
Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10
J. Biol. Chem.
2011
286
|
| 21890625 |
Zhang W et al.:
Tbx20 transcription factor is a downstream mediator for bone morphogenetic protein-10 in regulating cardiac ventricular wall development and function
J. Biol. Chem.
2011
286
|
| 22996691 |
Huang J et al.:
Myocardin regulates BMP10 expression and is required for heart development
J. Clin. Invest.
2012
122: 3678-3691
|
| 15073151 |
Chen H et al. et al.:
BMP10 is essential for maintaining cardiac growth during murine cardiogenesis
Development
2004
131: 2219-2231
|
| 22733989 |
Kim W et al.:
Loss of endothelial furin leads to cardiac malformation and early postnatal death
Mol. Cell. Biol.
2012
32: 3382-3391
|
| 30840660 |
Dupays L et al.:
Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function
PLoS ONE
2019
14
|
| 25022354 |
Qian B et al.:
Common variations in BMP4 confer genetic susceptibility to sporadic congenital heart disease in a Han Chinese population
Pediatr Cardiol
2014
35: 1442-1447
|
| 11418590 |
Hosoda T et al.:
A novel myocyte-specific gene Midori promotes the differentiation of P19CL6 cells into cardiomyocytes
J. Biol. Chem.
2001
276
|
| 16823493 |
Garcia-Gras E et al.:
Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy
J. Clin. Invest.
2006
116: 2012-2021
|
| 24533076 |
Wang J et al.:
A genetic variant in vitamin B12 metabolic genes that reduces the risk of congenital heart disease in Han Chinese populations
PLoS ONE
2014
9
|
| 25658937 |
Huang M et al.:
EMILIN2 regulates platelet activation, thrombus formation, and clot retraction
PLoS One
2015
10
|
| 21658281 |
Aouizerat BE et al.:
GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease
BMC Cardiovasc Disord
2011
11: 29
|
| 20643351 |
Kinzel D et al.:
Pitchfork regulates primary cilia disassembly and left-right asymmetry
Dev. Cell
2010
19: 66-77
|
| 26739162 |
Anazi S et al.:
Confirming the candidacy of THOC6 in the etiology of intellectual disability
Am J Med Genet A
2016
170
|
| 19654211 |
Clement CA et al.:
The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation
J. Cell. Sci.
2009
122: 3070-3082
|
| 9136932 |
Kuo CT et al.:
GATA4 transcription factor is required for ventral morphogenesis and heart tube formation
Genes Dev.
1997
11: 1048-1060
|
| 23040494 |
Ackerman C et al. et al.:
An excess of deleterious variants in VEGF-A pathway genes in Down-syndrome-associated atrioventricular septal defects
Am J Hum Genet
2012
91: 646-659
|
| 28905115 |
Fu F et al.:
Clinical application of SNP array analysis in fetuses with ventricular septal defects and normal karyotypes
Arch Gynecol Obstet
2017
296: 929-940
|
| 23678540 |
Ghanbari A et al.:
Sonic hedgehog inhibition induces mouse embryonic stem cells to differentiate toward definitive endoderm
Indian J. Exp. Biol.
2013
51: 201-207
|
| 28693388 |
Petrov K et al.:
Sending and Receiving Hedgehog Signals
Annu. Rev. Cell Dev. Biol.
2017
33: 145-168
|
| 23469020 |
et al.:
|
| 22199256 |
Voronova A et al.:
Gli2 and MEF2C activate each others expression and function synergistically during cardiomyogenesis in vitro
Nucleic Acids Res.
2012
40: 3329-3347
|
| 29257216 |
Liu F et al. et al.:
Molecular mechanisms of Ellisvan Creveld gene variations in ventricular septal defect
Mol Med Rep
2018
17: 1527-1536
|
| 29722020 |
Digilio MC et al.:
Atrioventricular canal defect and genetic syndromes: The unifying role of sonic hedgehog
Clin. Genet.
2019
95: 268-276
|
| 15936751 |
Washington Smoak I et al.:
Sonic hedgehog is required for cardiac outflow tract and neural crest cell development
Dev. Biol.
2005
283: 357-372
|
| 15793308 |
Gianakopoulos PJ et al.:
Hedgehog signaling induces cardiomyogenesis in P19 cells
J. Biol. Chem.
2005
280
|
| 21653639 |
Friedland-Little JM et al.:
A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus
Hum. Mol. Genet.
2011
20: 3725-3737
|
| 18924235 |
McCulley DJ et al.:
BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve development
Dev Dyn
2008
237: 3200-3209
|
| 18488998 |
Ocbina PJ et al.:
Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts
Dev. Dyn.
2008
237: 2030-2038
|
| 23410880 |
Fahed AC et al.:
Genetics of congenital heart disease: the glass half empty
Circ. Res.
2013
112: 707-720
|
| 26378977 |
Anderson RH et al.:
Insights regarding the normal and abnormal formation of the atrial and ventricular septal structures
Clin Anat
2016
29: 290-304
|
| 21454626 |
Liu H et al.:
Functional redundancy between human SHOX and mouse Shox2 genes in the regulation of sinoatrial node formation and pacemaking function
J. Biol. Chem.
2011
286
|
| 21165553 |
Wang J et al.:
A novel NKX2-5 mutation in familial ventricular septal defect
Int J Mol Med
2011
27: 369-375
|
| 24614889 |
Zhang L et al. et al.:
HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress
Nat Commun
2014
5: 3430
|
| 22366221 |
Nagel S et al.:
Microarray analysis of the global gene expression profile following hypothermia and transient focal cerebral ischemia
Neuroscience
2012
208: 109-122
|
| 26353049 |
Liu J et al.:
Generation and characterization of mice with a conditional null allele of the HtrA4 gene
Mol Med Rep
2015
12: 6768-6774
|
| 15371332 |
Mallat Z et al.:
Evidence for altered interleukin 18 (IL)-18 pathway in human heart failure
FASEB J.
2004
18: 1752-1754
|
| 15574430 |
Chandrasekar B et al.:
Interleukin-18 is a pro-hypertrophic cytokine that acts through a phosphatidylinositol 3-kinase-phosphoinositide-dependent kinase-1-Akt-GATA4 signaling pathway in cardiomyocytes
J. Biol. Chem.
2005
280: 4553-4567
|
| 9325300 |
Torigoe K et al. et al.:
Purification and characterization of the human interleukin-18 receptor
J. Biol. Chem.
1997
272
|
| 22503546 |
Dong C et al.:
Follow-up association study of linkage regions reveals multiple candidate genes for carotid plaque in Dominicans
Atherosclerosis
2012
223: 177-183
|
| 21898541 |
Oliveira FS et al.:
Hedgehog signaling and osteoblast gene expression are regulated by purmorphamine in human mesenchymal stem cells
J. Cell. Biochem.
2012
113: 204-208
|
| 12050137 |
Zhu J et al.:
beta8 integrins are required for vascular morphogenesis in mouse embryos
Development
2002
129: 2891-2903
|
| 25788663 |
Kumar V et al.:
Integrin beta 8 (ITGB8) regulates embryo implantation potentially via controlling the activity of TGF-B1 in mice
Biol. Reprod.
2015
92: 109
|
| 30450923 |
Stevenson MD et al.:
NADPH Oxidase 4 Regulates Inflammation in Ischemic Heart Failure: Role of Soluble Epoxide Hydrolase
Antioxid. Redox Signal.
2019
31: 39-58
|
| 16179589 |
Cucoranu I et al.:
NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts
Circ. Res.
2005
97: 900-907
|
| 25848754 |
Boulard M et al.:
FBXL10 protects Polycomb-bound genes from hypermethylation
Nat. Genet.
2015
47: 479-485
|
| 25371518 |
Chan KH et al.:
Shared molecular pathways and gene networks for cardiovascular disease and type 2 diabetes mellitus in women across diverse ethnicities
Circ Cardiovasc Genet
2014
7: 911-919
|
| 25564371 |
Gravez B et al.:
Aldosterone promotes cardiac endothelial cell proliferation in vivo
J Am Heart Assoc
2015
4
|
| 15623425 |
Shiroto K et al.:
MK2-/- gene knockout mouse hearts carry anti-apoptotic signal and are resistant to ischemia reperfusion injury
J. Mol. Cell. Cardiol.
2005
38: 93-97
|
| 16198317 |
Sudo T et al.:
p38 mitogen-activated protein kinase plays a key role in regulating MAPKAPK2 expression
Biochem. Biophys. Res. Commun.
2005
337: 415-421
|
| 24296264 |
Yu XH et al.:
NPC1, intracellular cholesterol trafficking and atherosclerosis
Clin. Chim. Acta
2014
429: 69-75
|
| 28562329 |
Yamada Y et al. et al.:
Identification of polymorphisms in 12q24.1, ACAD10, and BRAP as novel genetic determinants of blood pressure in Japanese by exome-wide association studies
Oncotarget
2017
8
|
| 29386187 |
Lahey R et al.:
Enhanced Redox State and Efficiency of Glucose Oxidation With miR Based Suppression of Maladaptive NADPH-Dependent Malic Enzyme 1 Expression in Hypertrophied Hearts
Circ. Res.
2018
122: 836-845
|
| 11804980 |
Fielitz J et al.:
Neutral endopeptidase is activated in cardiomyocytes in human aortic valve stenosis and heart failure
Circulation
2002
105: 286-289
|
| 20305660 |
Rudolph V et al. et al.:
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation
Nat. Med.
2010
16: 470-474
|
| 30032247 |
van der Pol A et al.:
OPLAH ablation leads to accumulation of 5-oxoproline, oxidative stress, fibrosis, and elevated fillings pressures: a murine model for heart failure with a preserved ejection fraction
Cardiovasc. Res.
2018
114: 1871-1882
|
| 29118264 |
van der Pol A et al. et al.:
Accumulation of 5-oxoproline in myocardial dysfunction and the protective effects of OPLAH
|
| 16939411 |
Van Q et al.:
Phospholipid scramblase-3 regulates cardiolipin de novo biosynthesis and its resynthesis in growing HeLa cells
Biochem. J.
2007
401: 103-109
|
| 31235787 |
Cordero P et al. et al.:
Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure
Nat Commun
2019
10: 2760
|
| 31185731 |
Alsina KM et al. et al.:
Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation
Circulation
2019
140: 681-693
|
| 29545372 |
Meng S et al.:
TBX20 Regulates Angiogenesis Through the Prokineticin 2-Prokineticin Receptor 1 Pathway
Circulation
2018
138: 913-928
|
| 19801577 |
Cook IH et al.:
Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway
Mol. Hum. Reprod.
2010
16: 158-169
|
| 25861302 |
Loniewska B et al.:
Association of functional genetic variants of A-kinase anchoring protein 10 with QT interval length in full-term Polish newborns
Arch Med Sci
2015
11: 149-154
|
| 28939891 |
Martinez-Martinez E et al.:
Differential Proteomics Identifies Reticulocalbin-3 as a Novel Negative Mediator of Collagen Production in Human Cardiac Fibroblasts
Sci Rep
2017
7: 12192
|
| 24983472 |
Barnette DN et al.:
RNA-seq analysis to identify novel roles of scleraxis during embryonic mouse heart valve remodeling
PLoS ONE
2014
9
|
| 16617122 |
Azfer A et al.:
Activation of endoplasmic reticulum stress response during the development of ischemic heart disease
Am. J. Physiol. Heart Circ. Physiol.
2006
291
|
| 17485520 |
Schroen B et al. et al.:
Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy
J. Exp. Med.
2007
204: 1227-1235
|
| 28336264 |
Molck MC et al.:
Genomic imbalances in syndromic congenital heart disease
J Pediatr (Rio J)
2017
93: 497-507
|
| 12742993 |
Kaynak B et al. et al.:
Genome-wide array analysis of normal and malformed human hearts
Circulation
2003
107: 2467-2474
|
| 31192914 |
Guerini FR et al.:
The Syntaxin-1A gene single nucleotide polymorphism rs4717806 associates with the risk of ischemic heart disease
Medicine (Baltimore)
2019
98
|
| 22945801 |
Peche VS et al. et al.:
Ablation of cyclase-associated protein 2 (CAP2) leads to cardiomyopathy
Cell. Mol. Life Sci.
2013
70: 527-543
|
| 31010896 |
Okur V et al.:
Homozygous noncanonical splice variant in LSM1 in two siblings with multiple congenital anomalies and global developmental delay
|
| 16472770 |
Zhang H et al.:
Identification of differentially expressed genes in human heart with ventricular septal defect using suppression subtractive hybridization
Biochem Biophys Res Commun
2006
342: 135-144
|
| 2901803 |
et al.:
[Fimbrial formation, antibiogram, plasmid content, lysotype and biotype of Salmonella]
Zentralblatt Veterinarmedizin Reihe B
1988
35: 138-151
|
| 26306646 |
Koolen DA et al. et al.:
The Koolen-de Vries syndrome: a phenotypic comparison of patients with a 17q21.31 microdeletion versus a KANSL1 sequence variant
Eur J Hum Genet
2016
24: 652-659
|
| 23906836 |
Wieczorek D et al. et al.:
A comprehensive molecular study on Coffin-Siris and Nicolaides-Baraitser syndromes identifies a broad molecular and clinical spectrum converging on altered chromatin remodeling
Hum. Mol. Genet.
2013
22: 5121-5135
|
| 25310850 |
Da M et al.:
Association of aminoacyl-tRNA synthetases gene polymorphisms with the risk of congenital heart disease in the Chinese Han population
PLoS ONE
2014
9
|
| 23637775 |
Nicholson TB et al. et al.:
A hypomorphic lsd1 allele results in heart development defects in mice
PLoS ONE
2013
8
|
| 22253135 |
Li A et al.:
The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart development
Proteomics
2012
12: 203-225
|
| 11397868 |
Popovici RM et al.:
Hypoxia regulates insulin-like growth factor-binding protein 1 in human fetal hepatocytes in primary culture: suggestive molecular mechanisms for in utero fetal growth restriction caused by uteroplacental insufficiency
J. Clin. Endocrinol. Metab.
2001
86: 2653-2659
|
| 29794428 |
Li W et al.:
Gremlin2 Regulates the Differentiation and Function of Cardiac Progenitor Cells via the Notch Signaling Pathway
Cell. Physiol. Biochem.
2018
47: 579-589
|
| 21457232 |
Iascone M et al. et al.:
Identification of de novo mutations and rare variants in hypoplastic left heart syndrome
Clin. Genet.
2012
81: 542-554
|
| 26940657 |
Gabriel BM et al.:
The Hippo signal transduction network for exercise physiologists
J. Appl. Physiol.
2016
120: 1105-1117
|
| 25033200 |
Adhikari N et al. et al.:
Identification of a new target of miR-16, Vacuolar Protein Sorting 4a
PLoS ONE
2014
9
|
| 18498376 |
Weisschuh N et al.:
A novel mutation in the FOXC1 gene in a family with Axenfeld-Rieger syndrome and Peters anomaly
Clin. Genet.
2008
74: 476-480
|
| 9600746 |
author information missing
Congenital heart disease in Robinow syndrome
Am. J. Med. Genet.
1998
77: 332-333
|
| 29276006 |
White JJ et al. et al.:
WNT Signaling Perturbations Underlie the Genetic Heterogeneity of Robinow Syndrome
Am. J. Hum. Genet.
2018
102: 27-43
|
| 18076106 |
Posch MG et al.:
Mutations in GATA4, NKX2.5, CRELD1, and BMP4 are infrequently found in patients with congenital cardiac septal defects
Am J Med Genet A
2008
146A: 251-253
|
| 23847438 |
Cheng KS et al.:
Circulating matrix metalloproteinase-2 and -9 enzyme activities in the children with ventricular septal defect
Int. J. Biol. Sci.
2013
9: 557-563
|
| 24398584 |
Feng YM et al.:
Notch pathway regulates female germ cell meiosis progression and early oogenesis events in fetal mouse
Cell Cycle
2014
13: 782-791
|
| 20634189 |
Garcia-Cruz R et al.:
Dynamics of cohesin proteins REC8, STAG3, SMC1 beta and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes
Hum. Reprod.
2010
25: 2316-2327
|
| 31682623 |
Kim SM et al.:
Retinoic acid-stimulated ERK1/2 pathway regulates meiotic initiation in cultured fetal germ cells
PLoS ONE
2019
14
|
| 19215321 |
Watkins AJ et al.:
Blastocyst environment and its influence on offspring cardiovascular health: the heart of the matter
J. Anat.
2009
215: 52-59
|
| 28936620 |
Vermeren M et al.:
Osteoclast stimulation factor 1 (Ostf1) KNOCKOUT increases trabecular bone mass in mice
Mamm. Genome
2017
28: 498-514
|
| 19935741 |
Du XJ et al.:
Cardiovascular effects of relaxin: from basic science to clinical therapy
Nat Rev Cardiol
2010
7: 48-58
|
| 20031959 |
Heidecker B et al.:
The gene expression profile of patients with new-onset heart failure reveals important gender-specific differences
Eur. Heart J.
2010
31: 1188-1196
|
| 14522967 |
Liu C et al.:
Identification of relaxin-3/INSL7 as a ligand for GPCR142
J. Biol. Chem.
2003
278
|
| 14522968 |
Liu C et al.:
Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135
J. Biol. Chem.
2003
278
|
| 15525639 |
Liu C et al. et al.:
INSL5 is a high affinity specific agonist for GPCR142 (GPR100)
J. Biol. Chem.
2005
280: 292-300
|
| 27243554 |
Ang SY et al.:
Signal transduction pathways activated by insulin-like peptide 5 at the relaxin family peptide RXFP4 receptor
Br. J. Pharmacol.
2017
174: 1077-1089
|
| 27888281 |
Ang SY et al.:
The actions of relaxin family peptides on signal transduction pathways activated by the relaxin family peptide receptor RXFP4
Naunyn Schmiedebergs Arch. Pharmacol.
2017
390: 105-111
|
| 29535183 |
Ang SY et al.:
INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells
J. Mol. Endocrinol.
2018
60: 213-224
|
| 22683086 |
Krawitz PM et al. et al.:
Mutations in PIGO, a member of the GPI-anchor-synthesis pathway, cause hyperphosphatasia with mental retardation
Am. J. Hum. Genet.
2012
91: 146-151
|
| 26434682 |
Lin YJ et al. et al.:
Genetic variants in PLCB4/PLCB1 as susceptibility loci for coronary artery aneurysm formation in Kawasaki disease in Han Chinese in Taiwan
Sci Rep
2015
5: 14762
|
| 20357282 |
Moslemi AR et al.:
Glycogenin-1 deficiency and inactivated priming of glycogen synthesis
N. Engl. J. Med.
2010
362: 1203-1210
|
| 30289950 |
Manichaikul A et al. et al.:
Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease
PLoS ONE
2018
13
|
| 15365454 |
Tatton-Brown K et al.:
Clinical features of NSD1-positive Sotos syndrome
Clin. Dysmorphol.
2004
13: 199-204
|
| 24720490 |
Thorsson T et al. et al.:
Chromosomal Imbalances in Patients with Congenital Cardiac Defects: A Meta-analysis Reveals Novel Potential Critical Regions Involved in Heart Development
Congenit Heart Dis
2015
10: 193-208
|
| 21626137 |
Slavin TP et al.:
Two-marker association tests yield new disease associations for coronary artery disease and hypertension
Hum. Genet.
2011
130: 725-733
|
| 30943206 |
Dong G et al.:
Presence and function of stress granules in atrial fibrillation
PLoS ONE
2019
14
|
| 23026201 |
Brunt KR et al.:
Role of WNT/beta-catenin signaling in rejuvenating myogenic differentiation of aged mesenchymal stem cells from cardiac patients
Am. J. Pathol.
2012
181: 2067-2078
|
| 30940143 |
Zhu Z et al. et al.:
Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis
Respir. Res.
2019
20: 64
|
| 30877150 |
Yang J et al.:
The emerging role of sorting nexins in cardiovascular diseases
Clin. Sci.
2019
133: 723-737
|
| 26214276 |
Lee JH et al.:
Genetic Modifiers of Age at Onset in Carriers of the G206A Mutation in PSEN1 With Familial Alzheimer Disease Among Caribbean Hispanics
JAMA Neurol
2015
72: 1043-1051
|
| 29414832 |
Xu S et al.:
Overexpression of SNX3 Decreases Amyloid-beta Peptide Production by Reducing Internalization of Amyloid Precursor Protein
Neurodegener Dis
2018
18: 26-37
|
| 25754594 |
Boehm E et al.:
Role of FAST Kinase Domains 3 (FASTKD3) in Post-transcriptional Regulation of Mitochondrial Gene Expression
J. Biol. Chem.
2016
291
|
| 15493068 |
Shimasaki N et al.:
EYA1 mutation in a newborn female presenting with cardiofacial syndrome
Pediatr Cardiol
2004
25: 411-413
|
| 17975119 |
Shiffman D et al. et al.:
Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study
Arterioscler. Thromb. Vasc. Biol.
2008
28: 173-179
|
| 30359586 |
Lu Y et al.:
The expression and clinical correlations of 4-1BB on peripheral CD4+ T cell subsets in patients with coronary artery disease. A cross-sectional pilot study
Clin. Chim. Acta
2018
487: 341-348
|
| 18157088 |
Witt CC et al.:
Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2
EMBO J.
2008
27: 350-360
|
| 21185285 |
Perera S et al.:
Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover
Dev. Biol.
2011
351: 46-61
|
| 18077800 |
Olichney JM et al.:
Patients with MCI and N400 or P600 abnormalities are at very high risk for conversion to dementia
Neurology
2008
70: 1763-1770
|
| 25424645 |
Parsons K et al.:
p600/UBR4 in the central nervous system
Cell. Mol. Life Sci.
2015
72: 1149-1160
|
| 27212118 |
Wei Y et al.:
UFMylation: A Unique & Fashionable Modification for Life
Genomics Proteomics Bioinformatics
2016
14: 140-146
|
| 22553207 |
Chen D et al.:
Dual function of the UNC-45b chaperone with myosin and GATA4 in cardiac development
J. Cell. Sci.
2012
125: 3893-3903
|
| 15140898 |
Chen HH et al.:
Vgl-4, a novel member of the vestigial-like family of transcription cofactors, regulates alpha1-adrenergic activation of gene expression in cardiac myocytes
J. Biol. Chem.
2004
279
|
| 30294252 |
Overall RW et al.:
The Small World of Adult Hippocampal Neurogenesis
Front Neurosci
2018
12: 641
|
| 28105635 |
Tardieu C et al. et al.:
Dental and extra-oral clinical features in 41 patients with WNT10A gene mutations: A multicentric genotype-phenotype study
Clin. Genet.
2017
92: 477-486
|
| 20889584 |
Bossers K et al.:
Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimers disease
Brain
2010
133: 3699-3723
|
| 30753098 |
Mun D et al.:
Expression of miRNAs in circulating exosomes derived from patients with persistent atrial fibrillation
FASEB J.
2019
33: 5979-5989
|
| 23571024 |
Xia Y et al.:
Label-free quantitative proteomic analysis of right ventricular remodeling in infant Tetralogy of Fallot patients
J Proteomics
2013
84: 78-91
|
| 30242883 |
Meng Z et al.:
Whole transcriptome sequencing reveals biologically significant RNA markers and related regulating biological pathways in cardiomyocyte hypertrophy induced by high glucose
J. Cell. Biochem.
2019
120: 1018-1027
|
| 28164238 |
Darwich R et al.:
KLF13 is a genetic modifier of the Holt-Oram syndrome gene TBX5
Hum. Mol. Genet.
2017
26: 942-954
|
| 17245133 |
Nemer M et al.:
The KLF family of transcriptional regulators in cardiomyocyte proliferation and differentiation
Cell Cycle
2007
6: 117-121
|
| 30402224 |
Yamada Y et al.:
Identification of 26 novel loci that confer susceptibility to early-onset coronary artery disease in a Japanese population
Biomed Rep
2018
9: 383-404
|
| 28839241 |
Duzen IV et al.:
Leukocyte TRP channel gene expressions in patients with non-valvular atrial fibrillation
Sci Rep
2017
7: 9272
|
| 27185748 |
Patel KP et al.:
Renal Denervation Improves Exaggerated Sympathoexcitation in Rats With Heart Failure: A Role for Neuronal Nitric Oxide Synthase in the Paraventricular Nucleus
Hypertension
2016
68: 175-184
|
| 29101166 |
Wu Q et al.:
Transcription factor DeltaFosB acts within the nucleus of the solitary tract to increase mean arterial pressure during exposures to intermittent hypoxia
Am. J. Physiol. Heart Circ. Physiol.
2018
314: H270-H277
|
| 29626090 |
Ramachandran B et al.:
A GTPase-activating protein-binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells
J. Biol. Chem.
2018
293: 7942-7968
|
| 22791291 |
Axelsson J et al.:
Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice
Blood
2012
120: 1742-1751
|
| 10187838 |
Kobayashi M et al.:
Molecular cloning and characterization of a human uronyl 2-sulfotransferase that sulfates iduronyl and glucuronyl residues in dermatan/chondroitin sulfate
J. Biol. Chem.
1999
274
|
| 31845005 |
Lei J et al.:
Abnormal expression of chondroitin sulfate sulfotransferases in the articular cartilage of pediatric patients with Kashin-Beck disease
Histochem. Cell Biol.
2020
153: 153-164
|
| 24535845 |
Hobbs CA et al.:
Conotruncal heart defects and common variants in maternal and fetal genes in folate, homocysteine, and transsulfuration pathways
Birth Defects Res. Part A Clin. Mol. Teratol.
2014
100: 116-126
|
| 21876188 |
Anderson DD et al.:
Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria
Proc. Natl. Acad. Sci. U.S.A.
2011
108
|
| 28708512 |
Laskowski D et al.:
Insulin during in vitro oocyte maturation has an impact on development, mitochondria, and cytoskeleton in bovine day 8 blastocysts
Theriogenology
2017
101: 15-25
|
| 26597826 |
Lu Y et al.:
Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen related receptor beta
BMC Mol. Biol.
2015
16: 19
|
| 29170476 |
Do EK et al.:
Trib2 regulates the pluripotency of embryonic stem cells and enhances reprogramming efficiency
Exp. Mol. Med.
2017
49: e401
|
| 18643775 |
Deng J et al.:
Human tribbles homologue 2 is expressed in unstable regions of carotid plaques and regulates macrophage IL-10 in vitro
Clin. Sci.
2009
116: 241-248
|
| 31514070 |
Yue H et al.:
Comparative transcriptome analysis to elucidate the therapeutic mechanism of colchicine against atrial fibrillation
Biomed. Pharmacother.
2019
119
|
| 30898992 |
Liang K et al.:
The Expression and Clinical Significance of Spleen Tyrosine Kinase in Patients with Coronary Heart Disease
Med. Sci. Monit.
2019
25: 2112-2121
|
| 21642504 |
Buharalioglu CK et al.:
Angiotensin II-induced process of angiogenesis is mediated by spleen tyrosine kinase via VEGF receptor-1 phosphorylation
Am J Physiol Heart Circ Physiol
2011
301
|
| 20713593 |
Falet H et al.:
A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function
J. Exp. Med.
2010
207: 1967-1979
|
| 22776094 |
Miller YI et al.:
The SYK side of TLR4: signalling mechanisms in response to LPS and minimally oxidized LDL
Br. J. Pharmacol.
2012
167: 990-999
|
| 25246634 |
Trinath J et al.:
The WNT signaling pathway contributes to dectin-1-dependent inhibition of Toll-like receptor-induced inflammatory signature
Mol. Cell. Biol.
2014
34: 4301-4314
|
| 21317289 |
Chen Y et al.:
Dual Phosphorylation of suppressor of fused (Sufu) by PKA and GSK3beta regulates its stability and localization in the primary cilium
J. Biol. Chem.
2011
286
|
| 25833158 |
Monteiro da Rocha A et al.:
Loss of glycogen synthase kinase 3 isoforms during murine oocyte growth induces offspring cardiac dysfunction
Biol. Reprod.
2015
92: 127
|
| 23549082 |
Zhou J et al. et al.:
GSK-3alpha is a central regulator of age-related pathologies in mice
J. Clin. Invest.
2013
123: 1821-1832
|
| 29224834 |
Herr DJ et al.:
HDAC1 localizes to the mitochondria of cardiac myocytes and contributes to early cardiac reperfusion injury
J. Mol. Cell. Cardiol.
2018
114: 309-319
|
| 17397797 |
Visigalli R et al.:
Rapamycin stimulates arginine influx through CAT2 transporters in human endothelial cells
Biochim. Biophys. Acta
2007
1768: 1479-1487
|
| 15238257 |
Visigalli R et al.:
The stimulation of arginine transport by TNFalpha in human endothelial cells depends on NF-kappaB activation
Biochim. Biophys. Acta
2004
1664: 45-52
|
| 12142345 |
Casanello P et al.:
Intrauterine growth retardation is associated with reduced activity and expression of the cationic amino acid transport systems y+/hCAT-1 and y+/hCAT-2B and lower activity of nitric oxide synthase in human umbilical vein endothelial cells
Circ. Res.
2002
91: 127-134
|
| 23782575 |
Palomino Doza J et al. et al.:
Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallot
BMC Genet.
2013
14: 57
|
| 21622831 |
Satoh K et al.:
Rho-kinase: important new therapeutic target in cardiovascular diseases
Am. J. Physiol. Heart Circ. Physiol.
2011
301: H287-H296
|
| 20331858 |
Brattelid T et al.:
Reference gene alternatives to Gapdh in rodent and human heart failure gene expression studies
BMC Mol. Biol.
2010
11: 22
|
| 22131815 |
Wu G et al.:
Planar cell polarity signaling pathway in congenital heart diseases
J. Biomed. Biotechnol.
2011
2011
|
| 24719258 |
Westmuckett AD et al.:
Impaired sperm maturation in RNASE9 knockout mice
Biol. Reprod.
2014
90: 120
|
| 18992174 |
Liu J et al.:
Cloning, expression and location of RNase9 in human epididymis
BMC Res Notes
2008
1: 111
|
| 31572525 |
Duzen IV et al.:
Investigation of leukocyte RHO/ROCK gene expressions in patients with non-valvular atrial fibrillation
Exp Ther Med
2019
18: 2777-2782
|
| 12244061 |
Fujita H et al.:
Rapostlin is a novel effector of Rnd2 GTPase inducing neurite branching
J. Biol. Chem.
2002
277
|
| 11931639 |
Tanaka H et al.:
Vps4-A (vacuolar protein sorting 4-A) is a binding partner for a novel Rho family GTPase, Rnd2
Biochem. J.
2002
365: 349-353
|
| 15802625 |
Zhang L et al.:
A new cellular signaling mechanism for angiotensin II activation of NF-kappaB: An IkappaB-independent, RSK-mediated phosphorylation of p65
Arterioscler. Thromb. Vasc. Biol.
2005
25: 1148-1153
|
| 30813401 |
Lin L et al.:
Role of p90RSK in Kidney and Other Diseases
|
| 15064094 |
Yang Y et al.:
Glutathione-S-transferase A4-4 modulates oxidative stress in endothelium: possible role in human atherosclerosis
Atherosclerosis
2004
173: 211-221
|
| 27894865 |
Gago-Diaz M et al. et al.:
The genetic component of bicuspid aortic valve and aortic dilation. An exome-wide association study
J. Mol. Cell. Cardiol.
2017
102: 3-9
|
| 31614896 |
Cortada E et al.:
Trafficking and Function of the Voltage-Gated Sodium Channel beta2 Subunit
|
| 24339868 |
Molina-Navarro MM et al. et al.:
Differential gene expression of cardiac ion channels in human dilated cardiomyopathy
PLoS ONE
2013
8
|
| 11238277 |
Dhar Malhotra J et al.:
Characterization of sodium channel alpha- and beta-subunits in rat and mouse cardiac myocytes
Circulation
2001
103: 1303-1310
|
| 26171856 |
author information missing
Correction: Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats
PLoS ONE
2015
10
|
| 29598869 |
Messerli FH et al.:
Angiotensin-Converting Enzyme Inhibitors in Hypertension: To Use or Not to Use?
J. Am. Coll. Cardiol.
2018
71: 1474-1482
|
| 30227878 |
Liu C et al.:
ACE2 polymorphisms associated with cardiovascular risk in Uygurs with type 2 diabetes mellitus
Cardiovasc Diabetol
2018
17: 127
|
| 23463883 |
Bader M et al.:
ACE2, angiotensin-(1-7), and Mas: the other side of the coin
Pflugers Arch.
2013
465: 79-85
|
| 31607648 |
Villano G et al. et al.:
Hyperdynamic circulatory syndrome in a mouse model transgenic for SerpinB3
Ann Hepatol
2020
19: 36-43
|
| 15767466 |
Walters PE et al.:
Angiotensin-(1-7) acts as a vasodepressor agent via angiotensin II type 2 receptors in conscious rats
Hypertension
2005
45: 960-966
|
| 17997171 |
Benrick A et al.:
A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive population
Regul. Pept.
2008
146: 189-196
|
| 8641727 |
Tamura K et al.:
Tissue-specific regulation of angiotensinogen gene expression in spontaneously hypertensive rats
Hypertension
1996
27: 1216-1223
|
| 27660028 |
Yu L et al.:
Angiotensin-(1-5), an active mediator of renin-angiotensin system, stimulates ANP secretion via Mas receptor
Peptides
2016
86: 33-41
|
| 30048754 |
Mendoza-Torres E et al.:
Protection of the myocardium against ischemia/reperfusion injury by angiotensin-(1-9) through an AT2R and Akt-dependent mechanism
Pharmacol. Res.
2018
135: 112-121
|
| 17138938 |
Jankowski V et al. et al.:
Mass-spectrometric identification of a novel angiotensin peptide in human plasma
Arterioscler. Thromb. Vasc. Biol.
2007
27: 297-302
|
| 8876246 |
Zini S et al.:
Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release
Proc. Natl. Acad. Sci. U.S.A.
1996
93
|
| 29685688 |
Li T et al.:
Critical role of the chymase/angiotensin-(1-12) axis in modulating cardiomyocyte contractility
Int. J. Cardiol.
2018
264: 137-144
|
| 27465904 |
Ahmad S et al.:
Primacy of cardiac chymase over angiotensin converting enzyme as an angiotensin-(1-12) metabolizing enzyme
Biochem. Biophys. Res. Commun.
2016
478: 559-564
|
| 29371216 |
Chang L et al.:
Bmal1 in Perivascular Adipose Tissue Regulates Resting-Phase Blood Pressure Through Transcriptional Regulation of Angiotensinogen
Circulation
2018
138: 67-79
|
| 27217404 |
Tetzner A et al.:
G-Protein-Coupled Receptor MrgD Is a Receptor for Angiotensin-(1-7) Involving Adenylyl Cyclase, cAMP, and Phosphokinase A
Hypertension
2016
68: 185-194
|
| 21551322 |
Probst S et al.:
Sarcomere gene mutations in isolated left ventricular noncompaction cardiomyopathy do not predict clinical phenotype
Circ Cardiovasc Genet
2011
4: 367-374
|
| 21542804 |
Bosnyak S et al.:
Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors
Clin. Sci.
2011
121: 297-303
|
| 15809376 |
Kostenis E et al.:
G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor
Circulation
2005
111: 1806-1813
|
| 29928987 |
Gaidarov I et al.:
Angiotensin (1-7) does not interact directly with MAS1, but can potently antagonize signaling from the AT1 receptor
Cell. Signal.
2018
50: 9-24
|
| 12829792 |
Santos RA et al. et al.:
Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 8258-8263
|
| 28461604 |
Leonhardt J et al. et al.:
Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS
Hypertension
2017
69: 1128-1135
|
| 29706566 |
Pan X et al. et al.:
FGF21 Prevents Angiotensin II-Induced Hypertension and Vascular Dysfunction by Activation of ACE2/Angiotensin-(1-7) Axis in Mice
Cell Metab.
2018
27: 1323-1337.e5
|
| 25995315 |
Pironti G et al.:
Circulating Exosomes Induced by Cardiac Pressure Overload Contain Functional Angiotensin II Type 1 Receptors
Circulation
2015
131: 2120-2130
|
| 26497614 |
Lyu L et al.:
A critical role of cardiac fibroblast-derived exosomes in activating renin angiotensin system in cardiomyocytes
J. Mol. Cell. Cardiol.
2015
89: 268-279
|
| 29146157 |
Li G et al.:
Angiotensin-converting enzyme 2 activation ameliorates pulmonary endothelial dysfunction in rats with pulmonary arterial hypertension through mediating phosphorylation of endothelial nitric oxide synthase
J Am Soc Hypertens
2017
11: 842-852
|
| 19700132 |
Epelman S et al.:
Soluble angiotensin-converting enzyme 2 in human heart failure: relation with myocardial function and clinical outcomes
J. Card. Fail.
2009
15: 565-571
|
| 24054336 |
Shao Z et al.:
Increasing serum soluble angiotensin-converting enzyme 2 activity after intensive medical therapy is associated with better prognosis in acute decompensated heart failure
J. Card. Fail.
2013
19: 605-610
|
| 29962859 |
Cha SA et al.:
Angiotensin-(1-9) ameliorates pulmonary arterial hypertension via angiotensin type II receptor
Korean J. Physiol. Pharmacol.
2018
22: 447-456
|
| 30934934 |
Nehme A et al.:
An Update on the Tissue Renin Angiotensin System and Its Role in Physiology and Pathology
|
| 6172448 |
et al.:
Identification of a human neutrophil angiotension II-generating protease as cathepsin G
J. Clin. Invest.
1982
69: 25-30
|
| 22490446 |
Westwood BM et al.:
Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney
Peptides
2012
35: 190-195
|
| 22180785 |
Ahmad S et al.:
Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue
PLoS ONE
2011
6
|
| 2266130 |
Urata H et al.:
Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart
J. Biol. Chem.
1990
265
|
| 7836734 |
Miura S et al.:
Angiotensin II formation by an alternative pathway during exercise in humans
J. Hypertens.
1994
12: 1177-1181
|
| 6555043 |
author information missing
Confirmation of direct angiotensin formation by kallikrein
Biochem. J.
1983
213: 193-200
|
| 180981 |
et al.:
Formation of angiotensin III by angiotensin-converting enzyme
Biochem. J.
1976
155: 189-192
|
| 11707427 |
Albiston AL et al.:
Evidence that the angiotensin IV (AT(4)) receptor is the enzyme insulin-regulated aminopeptidase
J. Biol. Chem.
2001
276
|
| 21234308 |
Shahzad K et al.:
Gene Expression Signatures of Peripheral Blood Mononuclear Cells during the Early Post-Transplant Period in Patients Developing Cardiac Allograft Vasculopathy
J Transplant
2010
2010
|
| 31862877 |
Egerstedt A et al. et al.:
Profiling of the plasma proteome across different stages of human heart failure
Nat Commun
2019
10: 5830
|
| 27038740 |
Park BM et al.:
Angiotensin IV protects cardiac reperfusion injury by inhibiting apoptosis and inflammation via AT4R in rats
Peptides
2016
79: 66-74
|
| 9493859 |
Coleman JK et al.:
Autoradiographic identification of kidney angiotensin IV binding sites and angiotensin IV-induced renal cortical blood flow changes in rats
Peptides
1998
19: 269-277
|
| 24586402 |
Hinton DJ et al.:
Aberrant bone density in aging mice lacking the adenosine transporter ENT1
PLoS ONE
2014
9
|
| 32360841 |
Osman W et al.:
Genetics of type 2 diabetes and coronary artery disease and their associations with twelve cardiometabolic traits in the United Arab Emirates population
Gene
2020
750
|
| 32348783 |
Henry BM et al.:
Hyperinflammation and derangement of renin-angiotensin-aldosterone system in COVID-19: A novel hypothesis for clinically suspected hypercoagulopathy and microvascular immunothrombosis
Clin. Chim. Acta
2020
507: 167-173
|
| 7884001 |
Vaughan DE et al.:
Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the renin-angiotensin system and thrombosis
J. Clin. Invest.
1995
95: 995-1001
|
| 10886570 |
Nakamura S et al.:
Plasminogen activator inhibitor-1 expression is regulated by the angiotensin type 1 receptor in vivo
Kidney Int.
2000
58: 251-259
|
| 10432384 |
Gesualdo L et al.:
Angiotensin IV stimulates plasminogen activator inhibitor-1 expression in proximal tubular epithelial cells
Kidney Int.
1999
56: 461-470
|
| 17444273 |
Fintha A et al.:
Angiotensin II activates plasminogen activator inhibitor-I promoter in renal tubular epithelial cells via the AT1 receptor
Acta Physiol Hung
2007
94: 19-30
|
| 7593643 |
Kerins DM et al.:
Angiotensin induction of PAI-1 expression in endothelial cells is mediated by the hexapeptide angiotensin IV
J. Clin. Invest.
1995
96: 2515-2520
|
| 15835378 |
Tsujino T et al.:
Circadian expression of plasminogen activator inhibitor-1 in angiotensin II type 1a receptor knockout mice
Clin. Exp. Hypertens.
2005
27: 159-168
|
| 8641204 |
Yu K et al.:
Angiotensin II regulation of plasminogen activator inhibitor-1 gene expression in neurons of normotensive and spontaneously hypertensive rat brains
Endocrinology
1996
137: 2503-2513
|
| 23884911 |
Mogielnicki A et al.:
Angiotensin-(1-9) enhances stasis-induced venous thrombosis in the rat because of the impairment of fibrinolysis
J Renin Angiotensin Aldosterone Syst
2014
15: 13-21
|
| 18026570 |
Fraga-Silva RA et al.:
The antithrombotic effect of angiotensin-(1-7) involves mas-mediated NO release from platelets
Mol. Med.
2008
14: 28-35
|
| 12091055 |
Yoshida M et al.:
L-158,809 and (D-Ala(7))-angiotensin I/II (1-7) decrease PAI-1 release from human umbilical vein endothelial cells
Thromb Res
2002
105: 531-536
|
| 9260983 |
Abbas A et al.:
Angiotensin-(1-7) induces bradykinin-mediated hypotensive responses in anesthetized rats
Hypertension
1997
30: 217-221
|
| 19362461 |
Murata K et al.:
Mechanisms of complement activation, C4d deposition, and their contribution to the pathogenesis of antibody-mediated rejection
Transplant Rev (Orlando)
2009
23: 139-150
|
| 17317768 |
Li JP et al.:
Three Na+/Ca2+ exchanger (NCX) variants are expressed in mouse osteoclasts and mediate calcium transport during bone resorption
Endocrinology
2007
148: 2116-2125
|
| 17668452 |
Sosnoski DM et al.:
NCX3 is a major functional isoform of the sodium-calcium exchanger in osteoblasts
J. Cell. Biochem.
2008
103: 1101-1110
|
| 28445457 |
Luongo TS et al. et al.:
The mitochondrial Na(+)/Ca(2+) exchanger is essential for Ca(2+) homeostasis and viability
Nature
2017
545: 93-97
|
| 30850686 |
Bae JE et al. et al.:
Fine particulate matter (PM2.5) inhibits ciliogenesis by increasing SPRR3 expression via c-Jun activation in RPE cells and skin keratinocytes
Sci Rep
2019
9: 3994
|
| 32297675 |
Saraswati S et al.:
Small proline-rich repeat 3 is a novel coordinator of PDGFRbeta and integrin beta1 crosstalk to augment proliferation and matrix synthesis by cardiac fibroblasts
FASEB J.
2020
34: 7885-7904
|
| 24914048 |
Heim A et al.:
Jumonji domain containing protein 6 (Jmjd6) modulates splicing and specifically interacts with arginine-serine-rich (RS) domains of SR- and SR-like proteins
Nucleic Acids Res.
2014
42: 7833-7850
|
| 31039133 |
Parvatiyar MS et al. et al.:
Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy
|
| 24463937 |
Ocaranza MP et al. et al.:
Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis
J. Hypertens.
2014
32: 771-783
|
| 18178554 |
Liang J et al.:
A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages
J. Biol. Chem.
2008
283: 6337-6346
|
| 31686651 |
Loo TH et al.:
The mammalian LINC complex component SUN1 regulates muscle regeneration by modulating drosha activity
|
| 26476453 |
Li P et al.:
Inner nuclear envelope protein SUN1 plays a prominent role in mammalian mRNA export
Nucleic Acids Res.
2015
43: 9874-9888
|
| 29691054 |
Uzer G et al.:
Sun-mediated mechanical LINC between nucleus and cytoskeleton regulates betacatenin nuclear access
J Biomech
2018
74: 32-40
|
| 19390693 |
Yao J et al.:
SVOP is a nucleotide binding protein
PLoS ONE
2009
4: e5315
|
| 10477754 |
Page LJ et al.:
Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin
J. Cell Biol.
1999
146: 993-1004
|
| 18815278 |
Lui-Roberts WW et al.:
Aftiphilin and gamma-synergin are required for secretagogue sensitivity of Weibel-Palade bodies in endothelial cells
Mol. Biol. Cell
2008
19: 5072-5081
|
| 30022064 |
Zhu L et al.:
TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival
Nat Commun
2018
9: 2812
|
| 30801233 |
Osman I et al.:
TEAD1 (TEA Domain Transcription Factor 1) Promotes Smooth Muscle Cell Proliferation Through Upregulating SLC1A5 (Solute Carrier Family 1 Member 5)-Mediated Glutamine Uptake
Circ. Res.
2019
124: 1309-1322
|
| 28878117 |
Liu R et al. et al.:
Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy
|
| 29680477 |
Mammoto A et al.:
YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1alpha
Microvasc. Res.
2018
119: 73-83
|
| 29154888 |
Hou N et al.:
Activation of Yap1/Taz signaling in ischemic heart disease and dilated cardiomyopathy
Exp. Mol. Pathol.
2017
103: 267-275
|
| 30771694 |
Li Q et al.:
Force-induced decline of TEA domain family member 1 contributes to osteoclastogenesis via regulation of Osteoprotegerin
Arch. Oral Biol.
2019
100: 23-32
|
| 24833797 |
Gonzalez-Santamaria J et al.:
Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction
Cardiovasc. Res.
2016
109: 67-78
|
| 22763477 |
Ohmura H et al.:
Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice
Hypertens. Res.
2012
35: 1063-1068
|
| 24803075 |
Gasso P et al.:
Influence of ABO genotype and phenotype on angiotensin-converting enzyme plasma activity
J Renin Angiotensin Aldosterone Syst
2014
15: 580-584
|
| 22258027 |
Gasso P et al.:
A common variant of the ABO gene protects against hypertension in a Spanish population
Hypertens. Res.
2012
35: 592-596
|
| 28174624 |
Fernandez-Atucha A et al.:
Sex differences in the aging pattern of renin-angiotensin system serum peptidases
Biol Sex Differ
2017
8: 5
|
| 26519689 |
Yoneshima E et al.:
The Transcription Factor EB (TFEB) Regulates Osteoblast Differentiation Through ATF4/CHOP-Dependent Pathway
J. Cell. Physiol.
2016
231: 1321-1333
|
| 23599343 |
Ferron M et al.:
A RANKL-PKCbeta-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts
Genes Dev.
2013
27: 955-969
|
| 692685 |
author information missing
Human urinary kallikrein converts inactive to active renin and is a possible physiological activator of renin
Nature
1978
275: 144-145
|
| 11850626 |
Wilkinson B et al.:
TOX: an HMG box protein implicated in the regulation of thymocyte selection
Nat Immunol
2002
3: 272-280
|
| 18403595 |
Koka V et al.:
Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway
Am. J. Pathol.
2008
172: 1174-1183
|
| 27965422 |
Uri K et al.:
Circulating ACE2 activity correlates with cardiovascular disease development
|
| 23160880 |
Pena Silva RA et al.:
Impact of ACE2 deficiency and oxidative stress on cerebrovascular function with aging
Stroke
2012
43: 3358-3363
|
| 11836266 |
Sawathiparnich P et al.:
Spironolactone abolishes the relationship between aldosterone and plasminogen activator inhibitor-1 in humans
J. Clin. Endocrinol. Metab.
2002
87: 448-452
|
| 27754866 |
Nehme A et al.:
Transcriptomic Analysis Reveals Novel Transcription Factors Associated With Renin-Angiotensin-Aldosterone System in Human Atheroma
Hypertension
2016
68: 1375-1384
|
| 27045029 |
Briet M et al.:
Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors
Hypertension
2016
67: 897-905
|
| 9314843 |
Pan J et al.:
Role of angiotensin II in activation of the JAK/STAT pathway induced by acute pressure overload in the rat heart
Circ. Res.
1997
81: 611-617
|
| 12601168 |
Boheler KR et al.:
Sex- and age-dependent human transcriptome variability: implications for chronic heart failure
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 2754-2759
|
| 30571167 |
Xu Y et al. et al.:
Sin1 (Stress-Activated Protein Kinase-Interacting Protein) Regulates Ischemia-Induced Microthrombosis Through Integrin alphaIIbbeta3-Mediated Outside-In Signaling and Hypoxia Responses in Platelets
Arterioscler. Thromb. Vasc. Biol.
2018
38: 2793-2805
|
| 30483777 |
Yan B et al.:
UBIAD1 expression is associated with cardiac hypertrophy in spontaneously hypertensive rats
Mol Med Rep
2019
19: 651-659
|
| 26890002 |
Liu S et al.:
Role of UBIAD1 in Intracellular Cholesterol Metabolism and Vascular Cell Calcification
PLoS ONE
2016
11
|
| 28901410 |
Yan B et al.:
Depletion of ubiA prenyltransferase domain containing 1 expression promotes angiotensin IIinduced hypertrophic response in AC16 human myocardial cells via modulating the expression levels of coenzyme Q10 and endothelial nitric oxide synthase
Mol Med Rep
2017
16: 6910-6915
|
| 32004434 |
De Bortoli M et al. et al.:
Novel Missense Variant in MYL2 Gene Associated With Hypertrophic Cardiomyopathy Showing High Incidence of Restrictive Physiology
Circ Genom Precis Med
2020
13
|
| 22537386 |
Bandau S et al.:
UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1alpha accumulation
BMC Biol.
2012
10: 36
|
| 30003813 |
Giamouridis D et al.:
Urocortin 3 Gene Transfer Increases Function of the Failing Murine Heart
Hum. Gene Ther.
2019
30: 10-20
|
| 16825287 |
Rademaker MT et al.:
Urocortin 3: haemodynamic, hormonal, and renal effects in experimental heart failure
Eur. Heart J.
2006
27: 2088-2098
|
| 30616890 |
Fasehee H et al.:
Cancer biomarkers in atherosclerotic plaque: Evidenced from structural and proteomic analyses
Biochem. Biophys. Res. Commun.
2019
509: 687-693
|
| 28155613 |
Souza Bomfim GH et al.:
Functional Upregulation of STIM-1/Orai-1-Mediated Store-Operated Ca2+ Contributing to the Hypertension Development Elicited by Chronic EtOH Consumption
Curr Vasc Pharmacol
2017
15: 265-281
|
| 25480151 |
et al.:
Uronyl 2-O sulfotransferase potentiates Fgf2-induced cell migration
J. Cell. Sci.
2015
128: 460-471
|
| 30661165 |
Guo Y et al.:
Decreased Expression of CHST-12, CHST-13, and UST in the Proximal Interphalangeal Joint Cartilage of School-Age Children with Kashin-Beck Disease: an Endemic Osteoarthritis in China Caused by Selenium Deficiency
Biol Trace Elem Res
2019
191: 276-285
|
| 31938322 |
Zhao J et al.:
Genetic polymorphisms of UTS2 rs2890565 Ser89Asn in coronary heart disease and myocardial infarction in Chinese population
Int J Clin Exp Pathol
2018
11: 2125-2136
|
| 27941008 |
Zhao J et al.:
Genetic polymorphisms of UTS2 rs2890565 Ser89Asn in cardiac hypertrophy in Chinese Han population
Postgrad Med J
2017
93: 406-413
|
| 26811505 |
Zhao J et al.:
Role of UTS2 gene in the genetic susceptibility to atrial fibrillation in the Chinese population
Postgrad Med J
2016
92: 201-207
|
| 16866021 |
Yi L et al.:
Association of ACE, ACE2 and UTS2 polymorphisms with essential hypertension in Han and Dongxiang populations from north-western China
J. Int. Med. Res.
2006
34: 272-283
|
| 24481965 |
Chiu CZ et al.:
Angiotensin II and the JNK pathway mediate urotensin II expression in response to hypoxia in rat cardiomyocytes
J. Endocrinol.
2014
220: 233-246
|
| 10499587 |
Ames RS et al. et al.:
Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14
Nature
1999
401: 282-286
|
| 15618545 |
Djordjevic T et al.:
Human urotensin II is a novel activator of NADPH oxidase in human pulmonary artery smooth muscle cells
Arterioscler. Thromb. Vasc. Biol.
2005
25: 519-525
|
| 20038798 |
Sauzeau V et al.:
The Rho/Rac exchange factor Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells
J. Clin. Invest.
2010
120: 315-330
|
| 27815660 |
Yang C et al.:
Mitochondrial phosphatase PGAM5 regulates Keap1-mediated Bcl-xL degradation and controls cardiomyocyte apoptosis driven by myocardial ischemia/reperfusion injury
In Vitro Cell. Dev. Biol. Anim.
2017
53: 248-257
|
| 25921086 |
Liu X et al.:
The histone demethylase PHF8 represses cardiac hypertrophy upon pressure overload
Exp. Cell Res.
2015
335: 123-134
|
| 23593175 |
Zhang P et al.:
Protein analysis of atrial fibrosis via label-free proteomics in chronic atrial fibrillation patients with mitral valve disease
PLoS ONE
2013
8
|
| 23349189 |
Ait-Oufella H et al. et al.:
Group X secreted phospholipase A2 limits the development of atherosclerosis in LDL receptor-null mice
Arterioscler. Thromb. Vasc. Biol.
2013
33: 466-473
|
| 8449506 |
Hautala T et al.:
A large duplication in the gene for lysyl hydroxylase accounts for the type VI variant of Ehlers-Danlos syndrome in two siblings
Genomics
1993
15: 399-404
|
| 23525417 |
Wagsater D et al.:
Impaired collagen biosynthesis and cross-linking in aorta of patients with bicuspid aortic valve
J Am Heart Assoc
2013
2
|
| 18715275 |
Nishimura FT et al.:
Effects of functional polymorphisms related to catecholaminergic systems on changes in blood catecholamine and cardiovascular measures after alcohol ingestion in the Japanese population
Alcohol. Clin. Exp. Res.
2008
32: 1937-1946
|
| 31380418 |
Wang W et al.:
Integration of Gene Expression Profile Data to Verify Hub Genes of Patients with Stanford A Aortic Dissection
Biomed Res Int
2019
2019
|
| 30935928 |
Rahimi E et al.:
Nutrient sensing pathway genes expression dysregulated in patients with T2DM and coronary artery disease
Diabetes Res. Clin. Pract.
2019
151: 39-45
|
| 32420474 |
Raveendran VV et al.:
Protein arginine methyltransferase 6 mediates cardiac hypertrophy by differential regulation of histone H3 arginine methylation
Heliyon
2020
6
|
| 30422892 |
Zhang H et al.:
Detection of Putative Functional Single Nucleotide Polymorphisms in Blood Pressure Loci and Validation of Association Between Single Nucleotide Polymorphism in WBP1L and Hypertension in the Chinese Han Population
J. Cardiovasc. Pharmacol.
2019
73: 48-55
|
| 27745833 |
O'Grady GL et al. et al.:
Variants in the Oxidoreductase PYROXD1 Cause Early-Onset Myopathy with Internalized Nuclei and Myofibrillar Disorganization
Am. J. Hum. Genet.
2016
99: 1086-1105
|
| 15922870 |
Stolle K et al.:
Cloning, cellular localization, genomic organization, and tissue-specific expression of the TGFbeta1-inducible SMAP-5 gene
Gene
2005
351: 119-130
|
| 29301961 |
Zhan X et al.:
Structure of a human catalytic step I spliceosome
Science
2018
359: 537-545
|
| 29970596 |
Kretschmer J et al.:
The m(6)A reader protein YTHDC2 interacts with the small ribosomal subunit and the 5-3 exoribonuclease XRN1
RNA
2018
24: 1339-1350
|
| 28684312 |
Feng L et al.:
Up-regulation of 14-3-3beta plays a role in intimal hyperplasia following carotid artery injury in diabetic Sprague Dawley rats by promoting endothelial cell migration and proliferation
Biochem. Biophys. Res. Commun.
2017
490: 1237-1243
|
| 30224653 |
Evangelou E et al. et al.:
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
Nat. Genet.
2018
50: 1412-1425
|
| 25589740 |
Woolfrey KM et al.:
The palmitoyl acyltransferase DHHC2 regulates recycling endosome exocytosis and synaptic potentiation through palmitoylation of AKAP79/150
J. Neurosci.
2015
35: 442-456
|
| 18508921 |
Sharma C et al.:
DHHC2 affects palmitoylation, stability, and functions of tetraspanins CD9 and CD151
Mol. Biol. Cell
2008
19: 3415-3425
|
| 27918981 |
Lim YH et al.:
Modulation of blood pressure in response to low ambient temperature: The role of DNA methylation of zinc finger genes
Environ. Res.
2017
153: 106-111
|
| 20132730 |
Hu J et al. et al.:
KBTBD7, a novel human BTB-kelch protein, activates transcriptional activities of SRE and AP-1
BMB Rep
2010
43: 17-22
|
| 23781337 |
Ranieri M et al.:
Mitochondrial fusion proteins and human diseases
Neurol Res Int
2013
2013
|
| 32664164 |
Pang B et al.:
Identification of Target Genes in Hypertension and Left Ventricular Remodeling
Medicine (Baltimore)
2020
99
|
| 30797769 |
Ndrepepa G et al.:
Myeloperoxidase - A bridge linking inflammation and oxidative stress with cardiovascular disease
Clin. Chim. Acta
2019
493: 36-51
|
| 31883644 |
Szot JO et al. et al.:
Bi-allelic Mutations in NADSYN1 Cause Multiple Organ Defects and Expand the Genotypic Spectrum of Congenital NAD Deficiency Disorders
Am. J. Hum. Genet.
2020
106: 129-136
|
| 32738595 |
Vdovenko D et al.:
The adaptor protein c-Cbl-associated protein (CAP) limits pro-inflammatory cytokine expression by inhibiting the NF-kappaB pathway
Int. Immunopharmacol.
2020
87
|
| 12646235 |
Kato R et al.:
Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation
Biochem. Biophys. Res. Commun.
2003
302: 767-772
|
| 28979898 |
Khalil A et al.:
A Novel Mutation in FOXC1 in a Lebanese Family with Congenital Heart Disease and Anterior Segment Dysgenesis: Potential Roles for NFATC1 and DPT in the Phenotypic Variations
Front Cardiovasc Med
2017
4: 58
|
| 25205790 |
Glessner JT et al. et al.:
Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence data
Circ. Res.
2014
115: 884-896
|
| 3067577 |
Niikawa N et al.:
Kabuki make-up (Niikawa-Kuroki) syndrome: a study of 62 patients
Am. J. Med. Genet.
1988
31: 565-589
|
| 15623712 |
Schoser BG et al.:
Sudden cardiac death in myotonic dystrophy type 2
Neurology
2004
63: 2402-2404
|
| 30291896 |
Qian X et al.:
C-src tyrosine kinase gene rs1378942 polymorphism and hypertension in Asians: Review and meta-analysis
Clin. Chim. Acta
2018
487: 202-209
|
| 27684517 |
Ertem AG et al.:
Association between serum adropin level and burden of coronary artery disease in patients with non-ST elevation myocardial infarction
Anatol J Cardiol
2017
17: 119-124
|
| 30881871 |
Zheng J et al.:
Association between serum adropin level and coronary artery disease: a systematic review and meta-analysis
Cardiovasc Diagn Ther
2019
9: 1-7
|
| 27841878 |
Hoffmann TJ et al.:
Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation
Nat Genet
2017
49: 54-64
|
| 18268355 |
Castelletti F et al. et al.:
Mutations in FN1 cause glomerulopathy with fibronectin deposits
Proc Natl Acad Sci U S A
2008
105: 2538-2543
|
| 27338075 |
Goktas MT et al.:
Relationship between genetic polymorphisms of drug efflux transporter MDR1 (ABCB1) and response to losartan in hypertension patients
Eur Rev Med Pharmacol Sci
2016
20: 2460-2467
|
| 17372036 |
Eap CB et al.:
CYP3A5 and ABCB1 genes influence blood pressure and response to treatment, and their effect is modified by salt
Hypertension
2007
49: 1007-1014
|
| 17301693 |
Zolk O et al.:
MDR1 genotype-dependent regulation of the aldosterone system in humans
Pharmacogenet Genomics
2007
17: 137-144
|
| 1360010 |
Ueda K et al.:
Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone
J Biol Chem
1992
267
|
| 6756687 |
et al.:
Human kidney cathepsins B and H activate and lower the molecular weight of human inactive renin
Clin Exp Hypertens A
1982
4: 2149-2158
|
| 16046222 |
Luc G et al.:
Plasma cystatin-C and development of coronary heart disease: The PRIME Study
Atherosclerosis
2006
185: 375-380
|
| 20489058 |
Xie L et al.:
Cystatin C increases in cardiac injury: a role in extracellular matrix protein modulation
Cardiovasc Res
2010
87: 628-635
|
| 31668507 |
Lu Y et al.:
Angiotensin II-Induced vascular remodeling and hypertension involves cathepsin L/V- MEK/ERK mediated mechanism
Int J Cardiol
2020
298: 98-106
|
| 18163891 |
Puzer L et al.:
Cathepsin V, but not cathepsins L, B and K, may release angiostatin-like fragments from plasminogen
Biol Chem
2008
389: 195-200
|
| 15192101 |
Du X et al.:
Elastin degradation by cathepsin V requires two exosites
J Biol Chem
2013
288
|
| 10710290 |
Knowle D et al.:
Identification of an interaction between the angiotensin II receptor sub-type AT2 and the ErbB3 receptor, a member of the epidermal growth factor receptor family
Regul Pept
2000
87: 73-82
|
| 21672356 |
Sakamoto A et al.:
Expression profiling of the ephrin (EFN) and Eph receptor (EPH) family of genes in atherosclerosis-related human cells
J Int Med Res
2011
39: 522-527
|
| 23223967 |
Zambrano S et al.:
The renoprotective effect of L-carnitine in hypertensive rats is mediated by modulation of oxidative stress-related gene expression
Eur J Nutr
2013
52: 1649-1659
|
| 32529639 |
Wang Z et al.:
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2
J Cell Physiol
2020
235: 9538-9556
|
| 15958393 |
Xie L et al.:
Proteomic identification of insulin-like growth factor-binding protein-6 induced by sublethal H2O2 stress from human diploid fibroblasts
Mol Cell Proteomics
2005
4: 1273-1283
|
| 24944201 |
Grumbach Y et al.:
ERp29 regulates epithelial sodium channel functional expression by promoting channel cleavage
Am J Physiol Cell Physiol
2014
307: C701-C709
|
| 18463147 |
Brennan CH et al.:
Eph receptors and zonation in the rat adrenal cortex
J Endocrinol
2008
198: 185-191
|
| 19740102 |
Stalker TJ et al.:
Endothelial cell specific adhesion molecule (ESAM) localizes to platelet-platelet contacts and regulates thrombus formation in vivo
J Thromb Haemost
2009
7: 1886-1896
|
| 24297486 |
Nicolini G et al.:
LH, progesterone, and TSH can stimulate aldosterone in vitro: a study on normal adrenal cortex and aldosterone producing adenoma
Horm Metab Res
2014
46: 318-321
|
| 22947377 |
Giani JF et al.:
Upregulation of the angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas receptor axis in the heart and the kidney of growth hormone receptor knock-out mice
Growth Horm IGF Res
2012
22: 224-233
|
| 18296491 |
Pan CH et al.:
Interplay of angiotensin II and angiotensin(1-7) in the regulation of matrix metalloproteinases of human cardiocytes
Exp Physiol
2008
93: 599-612
|
| 28321013 |
Matsumoto A et al.:
Cystatin C-Adiponectin Complex in Plasma Associates with Coronary Plaque Instability
J Atheroscler Thromb
2017
24: 970-979
|
| 28549782 |
Becker BK et al.:
Central TrkB blockade attenuates ICV angiotensin II-hypertension and sympathetic nerve activity in male Sprague-Dawley rats
Auton Neurosci
2017
205: 77-86
|
| 21377515 |
Kim JM et al.:
Inhibition of NF-kappaB-induced inflammatory responses by angiotensin II antagonists in aged rat kidney
Exp Gerontol
2011
46: 542-548
|
| 28411231 |
Guo L et al.:
Angiotensin-(1-7) attenuates angiotensin II-induced cardiac hypertrophy via a Sirt3-dependent mechanism
Am J Physiol Heart Circ Physiol
2017
312: H980-H991
|
| 30236983 |
Hu H et al.:
Interleukin-22 receptor 1 upregulation and activation in hypoxic endothelial cells improves perfusion recovery in experimental peripheral arterial disease
Biochem Biophys Res Commun
2018
505: 60-66
|
| 31815869 |
Runhua M et al.:
FSTL3 Induces Lipid Accumulation and Inflammatory Response in Macrophages and Associates With Atherosclerosis
J Cardiovasc Pharmacol
2019
74: 566-573
|
| 31680642 |
Qiao XR et al.:
MiR-210-3p attenuates lipid accumulation and inflammation in atherosclerosis by repressing IGF2
Biosci Biotechnol Biochem
2020
84: 321-329
|
| 28044240 |
Dai Q et al.:
Insulin-like Growth Factor Binding Protein6 Associated with Neuronal Apoptosis Following Intracerebral Hemorrhage in Rats
Cell Mol Neurobiol
2017
37: 1207-1216
|
| 33275517 |
Viveiros A et al.:
Sex differences in COVID-19: candidate pathways, genetics of ACE2, and sex hormones
Am J Physiol Heart Circ Physiol
2021
320: H296-H304
|
| 29570986 |
Zhang J et al. et al.:
AMP-activated Protein Kinase Phosphorylation of Angiotensin-Converting Enzyme 2 in Endothelium Mitigates Pulmonary Hypertension
Am J Respir Crit Care Med
2018
198: 509-520
|
| 31362530 |
Bergmark BA et al.:
Metformin Use and Clinical Outcomes Among Patients With Diabetes Mellitus With or Without Heart Failure or Kidney Dysfunction: Observations From the SAVOR-TIMI 53 Trial
Circulation
2019
140: 1004-1014
|
| 26788046 |
Zhang F et al.:
Angiotensin-(1-7): new perspectives in atherosclerosis treatment
J Geriatr Cardiol
2015
12: 676-682
|
| 24633843 |
Ahmad S et al.:
Angiotensin-(1-12): a chymase-mediated cellular angiotensin II substrate
Curr Hypertens Rep
2014
16: 429
|
| 32388547 |
Oudit GY et al.:
Plasma angiotensin-converting enzyme 2: novel biomarker in heart failure with implications for COVID-19
Eur Heart J
2020
41: 1818-1820
|
| 32388565 |
Sama IE et al. et al.:
Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin-angiotensin-aldosterone inhibitors
Eur Heart J
2020
41: 1810-1817
|
| 24211583 |
Nagata S et al.:
Big angiotensin-25: a novel glycosylated angiotensin-related peptide isolated from human urine
Biochem Biophys Res Commun
2013
441: 757-762
|
| 15556048 |
Satoh M et al.:
Increased expression of tumor necrosis factor-alpha converting enzyme and tumor necrosis factor-alpha in peripheral blood mononuclear cells in patients with advanced congestive heart failure
Eur J Heart Fail
2004
6: 869-875
|
| 32984892 |
Wallentin L et al.:
Angiotensin-converting enzyme 2 (ACE2) levels in relation to risk factors for COVID-19 in two large cohorts of patients with atrial fibrillation
Eur Heart J
2020
41: 4037-4046
|
| 23312967 |
Ahmad S et al.:
Chymase mediates angiotensin-(1-12) metabolism in normal human hearts
J Am Soc Hypertens
2013
7: 128-136
|
| 23823979 |
Chan KH et al.:
Angiotensin-[1-12] interacts with angiotensin type I receptors
Neuropharmacology
2014
81: 267-273
|
| 17045572 |
Nagata S et al.:
Isolation and identification of proangiotensin-12, a possible component of the renin-angiotensin system
Biochem Biophys Res Commun
2006
350: 1026-1031
|
| 19147651 |
Prosser HC et al.:
Cardiac chymase converts rat proAngiotensin-12 (PA12) to angiotensin II: effects of PA12 upon cardiac haemodynamics
Cardiovasc Res
2009
82: 40-50
|
| 23812388 |
Moniwa N et al.:
Primacy of angiotensin converting enzyme in angiotensin-(1-12) metabolism
Am J Physiol Heart Circ Physiol
2013
305: H644-H650
|
| 33582209 |
Park BM et al.:
Cardio-protective effects of angiotensin-(1-5) via mas receptor in rats against ischemic-perfusion injury
Peptides
2021
139
|
| 31378915 |
Song XD et al.:
Alamandine protects rat from myocardial ischemia-reperfusion injury by activating JNK and inhibiting NF-kappaB
Eur Rev Med Pharmacol Sci
2019
23: 6718-6726
|
| 24812125 |
Kawasaki K et al. et al.:
Genetic variants of Adam17 differentially regulate TGFbeta signaling to modify vascular pathology in mice and humans
Proc Natl Acad Sci U S A
2014
111: 7723-7728
|
| 10404956 |
Okamura A et al.:
Upregulation of renin-angiotensin system during differentiation of monocytes to macrophages
J Hypertens
1999
17: 537-545
|
| 6294088 |
et al.:
The granulocyte-angiotensin system. Angiotensin I-converting activity of cathepsin G
J Biol Chem
1982
257
|
| 15831814 |
Esteban V et al.:
Angiotensin IV activates the nuclear transcription factor-kappaB and related proinflammatory genes in vascular smooth muscle cells
Circ Res
2005
96: 965-973
|
| 17684103 |
Wallis MG et al.:
Vasopressin is a physiological substrate for the insulin-regulated aminopeptidase IRAP
Am J Physiol Endocrinol Metab
2007
293
|
| 1978675 |
Ward PE et al.:
Metabolism of vasoactive peptides by plasma and purified renal aminopeptidase M
Biochem Pharmacol
1990
40: 1725-1732
|
| 12225947 |
Li YD et al.:
Activation of multiple signaling modules is critical in angiotensin IV-induced lung endothelial cell proliferation
Am J Physiol Lung Cell Mol Physiol
2002
283: L707-L716
|
| 11295571 |
Reaux A et al.:
Angiotensin III: a central regulator of vasopressin release and blood pressure
Trends Endocrinol Metab
2001
12: 157-162
|
| 22590974 |
Kumar R et al.:
The intracrine renin-angiotensin system
Clin Sci (Lond)
2012
123: 273-284
|
| 11053019 |
Chen S et al.:
Angiotensin IV-mediated pulmonary artery vasorelaxation is due to endothelial intracellular calcium release
Am J Physiol Lung Cell Mol Physiol
2000
279: L849-L856
|
| 9421435 |
Lu D et al.:
Angiotensin II-induced nuclear targeting of the angiotensin type 1 (AT1) receptor in brain neurons
Endocrinology
1998
139: 365-375
|
| 12364346 |
Liu HW et al.:
Effect of estrogen and AT1 receptor blocker on neointima formation
Hypertension
2002
40: 451-7;discussion448-50
|
| 15550614 |
Dean SA et al.:
17beta-estradiol downregulates tissue angiotensin-converting enzyme and ANG II type 1 receptor in female rats
Am J Physiol Regul Integr Comp Physiol
2005
288: R759-R766
|
| 23476748 |
Clark MA et al.:
Distinct Molecular Effects of Angiotensin II and Angiotensin III in Rat Astrocytes
Int J Hypertens
2013
2013
|
| 30978131 |
Escobales N et al.:
Mitochondrial angiotensin receptors and cardioprotective pathways
Am J Physiol Heart Circ Physiol
2019
316
|
| 15718497 |
Jaffe IZ et al.:
Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells
Circ Res
2005
96: 643-650
|
| 18256274 |
Li XC et al.:
Intracellular ANG II directly induces in vitro transcription of TGF-beta1, MCP-1, and NHE-3 mRNAs in isolated rat renal cortical nuclei via activation of nuclear AT1a receptors
Am J Physiol Cell Physiol
2008
294
|
| 18829990 |
Singh VP et al.:
Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis
Diabetes
2008
57: 3297-3306
|
| 8406654 |
Eggena P et al.:
Nuclear angiotensin receptors induce transcription of renin and angiotensinogen mRNA
Hypertension
1993
22: 496-501
|
| 20463030 |
Tadevosyan A et al.:
Nuclear-delimited angiotensin receptor-mediated signaling regulates cardiomyocyte gene expression
J Biol Chem
2010
285
|
| 11015597 |
Sinn PL et al.:
Identification of three human renin mRNA isoforms from alternative tissue-specific transcriptional initiation
Physiol Genomics
2000
3: 25-31
|
| 21852574 |
Abadir PM et al. et al.:
Identification and characterization of a functional mitochondrial angiotensin system
Proc Natl Acad Sci U S A
2011
108
|
| 19377080 |
Heringer-Walther S et al.:
Angiotensin-(1-7) stimulates hematopoietic progenitor cells in vitro and in vivo
Haematologica
2009
94: 857-860
|
| 25534429 |
Vuille-dit-Bille RN et al. et al.:
Human intestine luminal ACE2 and amino acid transporter expression increased by ACE-inhibitors
Amino Acids
2015
47: 693-705
|
| 32305401 |
Brojakowska A et al.:
Clinical Implications of SARS-CoV-2 Interaction With Renin Angiotensin System: JACC Review Topic of the Week
J Am Coll Cardiol
2020
75: 3085-3095
|
| 16179584 |
Keidar S et al.:
Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients
Circ Res
2005
97: 946-953
|
| 15159288 |
Mazak I et al.:
Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells
Circulation
2004
109: 2792-2800
|
| 16563347 |
Hsu M et al.:
Tissue-specific effects of statins on the expression of heme oxygenase-1 in vivo
Biochem Biophys Res Commun
2006
343: 738-744
|
| 29660382 |
Gong L et al.:
Elevated plasma soluble (pro)renin receptor levels are associated with left ventricular remodeling and renal function in chronic heart failure patients with reduced ejection fraction
Peptides
2019
111: 152-157
|
| 24582748 |
Yuan X et al.:
Atorvastatin attenuates myocardial remodeling induced by chronic intermittent hypoxia in rats: partly involvement of TLR-4/MYD88 pathway
Biochem Biophys Res Commun
2014
446: 292-297
|
| 19548630 |
Chansrichavala P et al.:
Atorvastatin attenuates TLR4-mediated NF-kappaB activation in a MyD88-dependent pathway
Asian Pac J Allergy Immunol
2009
27: 49-57
|
| 29998915 |
Park BM et al.:
Alamandine Protects the Heart Against Reperfusion Injury via the MrgD Receptor
Circ J
2018
82: 2584-2593
|
| 32232979 |
Han H et al.:
Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China
J Med Virol
2020
92: 819-823
|
| 24646643 |
Morimoto S et al.:
Serum soluble (pro)renin receptor levels in patients with essential hypertension
Hypertens Res
2014
37: 642-648
|
| 19221212 |
Masson R et al. et al.:
Onset of experimental severe cardiac fibrosis is mediated by overexpression of Angiotensin-converting enzyme 2
Hypertension
2009
53: 694-700
|
| 23140275 |
Hampson A et al.:
Synaptotagmin-like protein 4 and Rab8 interact and increase dense granule release in platelets
J Thromb Haemost
2013
11: 161-168
|
| 23249523 |
Dong XY et al.:
Dual functions of Insig proteins in cholesterol homeostasis
Lipids Health Dis
2012
11: 173
|
| 27106955 |
Phelan DG et al. et al.:
ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy
Eur Heart J
2016
37: 2586-2590
|
| 31629738 |
Fan C et al.:
Cardiomyocytes from CCND2-overexpressing human induced-pluripotent stem cells repopulate the myocardial scar in mice: A 6-month study
J Mol Cell Cardiol
2019
137: 25-33
|
| 19131340 |
Hou R et al.:
Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells
J Biol Chem
2009
284: 6955-6965
|
| 31967847 |
Arjaans S et al.:
Early angiogenic proteins associated with high risk for bronchopulmonary dysplasia and pulmonary hypertension in preterm infants
Am J Physiol Lung Cell Mol Physiol
2020
318: L644-L654
|
| 17663574 |
Zhou XW et al.:
Proteomic studies of PP2A-B56gamma1 phosphatase complexes reveal phosphorylation-regulated partners in cardiac local signaling
J Proteome Res
2007
6: 3433-3442
|
| 30212560 |
Radhakrishna U et al.:
Newborn blood DNA epigenetic variations and signaling pathway genes associated with Tetralogy of Fallot (TOF)
PLoS One
2018
13
|
| 34128175 |
Yang M et al. et al.:
The ER membrane protein complex subunit Emc3 controls angiogenesis via the FZD4/WNT signaling axis
|
| 34128175 |
Yang M et al. et al.:
The ER membrane protein complex subunit Emc3 controls angiogenesis via the FZD4/WNT signaling axis
|
| 29976771 |
Muthuramu I et al.:
Hepatocyte-Specific SR-BI Gene Transfer Corrects Cardiac Dysfunction in Scarb1-Deficient Mice and Improves Pressure Overload-Induced Cardiomyopathy
Arterioscler Thromb Vasc Biol
2018
38: 2028-2040
|
| 32376282 |
author information missing
article information missing
|
| 34133440 |
author information missing
article information missing
|
| 32128068 |
author information missing
article information missing
|
| 27916661 |
author information missing
article information missing
|
| 7889573 |
author information missing
article information missing
|
| 14676148 |
author information missing
article information missing
|
| 10219239 |
author information missing
article information missing
|
| 16361248 |
author information missing
article information missing
|
| 25281747 |
author information missing
article information missing
|
| 25648353 |
author information missing
article information missing
|
| 12485929 |
author information missing
article information missing
|
| 18948620 |
author information missing
article information missing
|
| 22515331 |
author information missing
article information missing
|
| 31672783 |
author information missing
article information missing
|
| 22844641 |
author information missing
article information missing
|
| 32471864 |
author information missing
article information missing
|
| 29438013 |
author information missing
article information missing
|
| 31551469 |
author information missing
article information missing
|
| 33415776 |
author information missing
article information missing
|
| 32958558 |
author information missing
article information missing
|
| 30605677 |
author information missing
article information missing
|
| 34592247 |
author information missing
article information missing
|
| 31882500 |
author information missing
article information missing
|
| 11499670 |
author information missing
article information missing
|
| 15331379 |
author information missing
article information missing
|
| 16444815 |
author information missing
article information missing
|
| 23742196 |
author information missing
article information missing
|
| 34782257 |
author information missing
article information missing
|
| 19062365 |
author information missing
article information missing
|
| 18212272 |
author information missing
article information missing
|
| 15321808 |
author information missing
article information missing
|
| 11961027 |
author information missing
article information missing
|
| 36127725 |
author information missing
article information missing
|
| 34264743 |
author information missing
article information missing
|
| 34382495 |
author information missing
article information missing
|
| 29208471 |
author information missing
article information missing
|
| 33857222 |
author information missing
article information missing
|
| 33398528 |
author information missing
article information missing
|
| 33660951 |
author information missing
article information missing
|
| 20706199 |
author information missing
article information missing
|
| 32103083 |
author information missing
article information missing
|
| 31830004 |
author information missing
article information missing
|
| 22566575 |
author information missing
article information missing
|
| 21059340 |
author information missing
article information missing
|
| 17098227 |
author information missing
article information missing
|
| 34801688 |
author information missing
article information missing
|
| 39649955 |
author information missing
article information missing
|
| 36918543 |
author information missing
article information missing
|
| 19074137 |
Deevska GM et al.:
Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice
J. Biol. Chem.
2009
284: 8359-8368
|
| 19478200 |
Verschuren L et al.:
MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease
Circ. Res.
2009
105: 99-107
|
| 20134099 |
Mandosi E et al.:
Atorvastatin downregulates monocyte CD36 expression, nuclear NFkappaB and TNFalpha levels in type 2 diabetes
J. Atheroscler. Thromb.
2010
17: 539-545
|
| 10400004 |
Kawano H et al.:
Hyperglycemia rapidly suppresses flow-mediated endothelium-dependent vasodilation of brachial artery.
J. Am. Coll. Cardiol.
1999
34: 146-154
|
| 19679829 |
Westmuckett AD et al.:
Lack of tyrosylprotein sulfotransferase activity in hematopoietic cells drastically attenuates atherosclerosis in Ldlr-/- mice
Arterioscler. Thromb. Vasc. Biol.
2009
29: 1730-1736
|
| 23185679 |
Munch G et al.:
Overexpression of ABCG1 protein attenuates arteriosclerosis and endothelial dysfunction in atherosclerotic rabbits
Heart Int
2012
7: E12
|
| 23628701 |
Hu FY et al.:
AGGF1 is a novel anti-inflammatory factor associated with TNF-alpha-induced endothelial activation
Cell. Signal.
2013
25: 1645-1653
|
| 16244876 |
author information missing
Proprotein convertases furin and PC5: targeting atherosclerosis and restenosis at multiple levels
J. Mol. Med.
2005
83: 865-875
|
| 24675658 |
Kuijpers MJ et al.:
Supporting roles of platelet thrombospondin-1 and CD36 in thrombus formation on collagen
Arterioscler. Thromb. Vasc. Biol.
2014
34: 1187-1192
|
| 26493158 |
Chistiakov DA et al.:
Macrophage-mediated cholesterol handling in atherosclerosis
J. Cell. Mol. Med.
2016
1: 17-28
|
| 24005217 |
Holdt LM et al.:
From genotype to phenotype in human atherosclerosis--recent findings
Curr. Opin. Lipidol.
2013
24: 410-418
|
| 15588017 |
author information missing
article information missing
|
| 27382511 |
et al.:
|
| 24506872 |
author information missing
article information missing
|
| 17080197 |
Lagace TA et al.:
Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice
J. Clin. Invest.
2006
116: 2995-3005
|
| 26950419 |
et al.:
Sortilin mediates vascular calcification via its recruitment into extracellular vesicles
J. Clin. Invest.
2016
126: 1323-1336
|
| 22986000 |
Li J et al.:
c-Ski inhibits the proliferation of vascular smooth muscle cells via suppressing Smad3 signaling but stimulating p38 pathway
Cell. Signal.
2013
25: 159-167
|
| 23413429 |
Huang Q et al.:
AIP1 suppresses atherosclerosis by limiting hyperlipidemia-induced inflammation and vascular endothelial dysfunction
Arterioscler. Thromb. Vasc. Biol.
2013
4: 795-804
|
| 12615673 |
Han SR et al.:
Enzymatically modified LDL induces cathepsin H in human monocytes: potential relevance in early atherogenesis
Arterioscler. Thromb. Vasc. Biol.
2003
4: 661-667
|
| 14699162 |
Shirakawa R et al.:
Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets
J. Biol. Chem.
2004
279
|
| 26680738 |
He J et al.:
Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses
Mol. Biol. Cell
2016
3: 572-587
|
| 26637270 |
Chicka MC et al.:
Role of Munc13-4 as a Ca2+-dependent tether during platelet secretion
Biochem. J.
2016
5: 627-639
|
| 24176643 |
Zhang Y et al.:
A network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils
Dev. Cell
2013
27: 215-226
|
| 22626270 |
Cristobo I et al.:
Usefulness of material recovered from distal embolic protection devices after carotid angioplasty for proteomic studies
J Vasc Interv Radiol
2012
23: 818-824
|
| 22508512 |
Boswell KL et al.:
Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion
J. Cell Biol.
2012
2: 301-312
|
| 26620734 |
Perisic L et al.:
Gene expression signatures, pathways and networks in carotid atherosclerosis
J. Intern. Med.
2016
279: 293-308
|
| 23553987 |
Cerecedo D et al.:
Haemostatic role of intermediate filaments in adhered platelets: importance of the membranous system stability
J. Cell. Biochem.
2013
114: 2050-2060
|
| 28066264 |
Chen X et al.:
Chronic Exercise Training Improved Aortic Endothelial and Mitochondrial Function via an AMPKalpha2-Dependent Manner
Front Physiol
2016
7: 631
|
| 25857312 |
Turczynska KM et al.:
Regulation of smooth muscle dystrophin and synaptopodin 2 expression by actin polymerization and vascular injury
Arterioscler. Thromb. Vasc. Biol.
2015
35: 1489-1497
|
| 12473559 |
Llorente-Cortes V et al.:
Low-density lipoprotein upregulates low-density lipoprotein receptor-related protein expression in vascular smooth muscle cells: possible involvement of sterol regulatory element binding protein-2-dependent mechanism
Circulation
2002
106: 3104-3110
|
| 25893733 |
Qin B et al.:
MicroRNA-221/222 regulate ox-LDL-induced endothelial apoptosis via Ets-1/p21 inhibition
Mol. Cell. Biochem.
2015
1-2: 115-124
|
| 26285183 |
de Gonzalo-Calvo D et al.:
Circulating soluble low-density lipoprotein receptor-related protein 1 (sLRP1) concentration is associated with hypercholesterolemia: A new potential biomarker for atherosclerosis
Int. J. Cardiol.
2015
201: 20-29
|
| 20835268 |
Zhu P et al.:
Matrine inhibits vascular smooth muscle cell proliferation by modulating the expression of cell cycle regulatory genes
Acta Pharmacol. Sin.
2010
31: 1329-1335
|
| 11549346 |
Choy JC et al.:
Endothelial cell apoptosis: biochemical characteristics and potential implications for atherosclerosis
J. Mol. Cell. Cardiol.
2001
9: 1673-1690
|
| 19742316 |
Zhou L et al.:
LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation
PLoS ONE
2009
4: E6922
|
| 25440057 |
Koeth RA et al.:
gamma-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO
Cell Metab.
2014
20: 799-812
|
| 24587332 |
Salsoso R et al.:
Reduced L-carnitine transport in aortic endothelial cells from spontaneously hypertensive rats
PLoS ONE
2014
9
|
| 26594106 |
Li YF et al.:
Lysophospholipids and their G protein-coupled receptors in atherosclerosis
Front Biosci (Landmark Ed)
2016
21: 70-88
|
| 25593281 |
Patel KM et al.:
Macrophage sortilin promotes LDL uptake, foam cell formation, and atherosclerosis
Circ. Res.
2015
116: 789-796
|
| 21526899 |
Solt LA et al.:
The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis
Future Med Chem
2011
3: 623-638
|
| 26296466 |
Chen YX et al.:
The Sirt1 activator SRT1720 attenuates angiotensin II-induced atherosclerosis in apoE(-)/(-) mice through inhibiting vascular inflammatory response
Biochem. Biophys. Res. Commun.
2015
465: 732-738
|
| 28120882 |
Chen Z et al.:
Haemodynamics Regulate Fibronectin Assembly via PECAM
Sci Rep
2017
7: 41223
|
| 22076424 |
Heo KS et al.:
Disturbed-flow-mediated vascular reactive oxygen species induce endothelial dysfunction
Circ. J.
2011
75: 2722-2730
|
| 23288162 |
Tarhouni K et al.:
Key role of estrogens and endothelial estrogen receptor alpha in blood flow-mediated remodeling of resistance arteries
Arterioscler. Thromb. Vasc. Biol.
2013
33: 605-611
|
| 25522185 |
Daimiel-Ruiz L et al.:
Dietary lipids modulate the expression of miR-107, an miRNA that regulates the circadian system
Mol Nutr Food Res
2015
59: 552-565
|
| 27834186 |
Dus-Zuchowska M et al.:
Twelve-week-conjugated linoleic acid supplementation has no effects on the selected markers of atherosclerosis in obese and overweight women
Food Nutr Res
2016
60: 32776
|
| 21042583 |
Stein S et al.:
ApoE-/- PGC-1alpha-/- mice display reduced IL-18 levels and do not develop enhanced atherosclerosis
PLoS ONE
2010
5
|
| 27037767 |
Bruen R et al.:
Atheroprotective effects of conjugated linoleic acid
Br J Clin Pharmacol
2017
1: 46-53
|
| 16182300 |
Toomey S et al.:
Profound resolution of early atherosclerosis with conjugated linoleic acid
Atherosclerosis
2006
187: 40-49
|
| 23070607 |
McCarthy C et al.:
IL-10 mediates the immunoregulatory response in conjugated linoleic acid-induced regression of atherosclerosis
FASEB J.
2013
27: 499-510
|
| 23964012 |
McCarthy C et al.:
Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid
EMBO Mol Med
2013
5: 1443-1457
|
| 9312047 |
Kotenko SV et al.:
Identification and functional characterization of a second chain of the interleukin-10 receptor complex
EMBO J.
1997
16: 5894-5903
|
| 27173919 |
Santilli F et al.:
Microparticles as new markers of cardiovascular risk in diabetes and beyond
Thromb. Haemost.
2016
116: 220-234
|
| 27088456 |
Silva-Martinez GA et al.:
Arachidonic and oleic acid exert distinct effects on the DNA methylome
Epigenetics
2016
11: 321-334
|
| 15896353 |
Bogatcheva NV et al.:
Arachidonic acid cascade in endothelial pathobiology
Microvasc. Res.
2005
69: 107-127
|
| 23940449 |
Tian-Tian Z et al.:
Functions of cyclophilin A in atherosclerosis
Exp Clin Cardiol
2013
18: E118-E124
|
| 24598757 |
Cousido-Siah A et al.:
Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design
Acta Crystallogr. D Biol. Crystallogr.
2014
70: 889-903
|
| 22615127 |
Satpathy AT et al.:
Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages
J. Exp. Med.
2012
209: 1135-1152
|
| 19520615 |
Niessner A et al.:
Dendritic cells in atherosclerotic disease
Clin. Immunol.
2010
134: 25-32
|
| 22357965 |
Rajwani A et al.:
Increasing circulating IGFBP1 levels improves insulin sensitivity, promotes nitric oxide production, lowers blood pressure, and protects against atherosclerosis
Diabetes
2012
61: 915-924
|
| 7775431 |
Greenfeder SA et al.:
Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex
J. Biol. Chem.
1995
270
|
| 9371760 |
Huang J et al.:
Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein
Proc. Natl. Acad. Sci. U.S.A.
1997
94
|
| 28607410 |
Yang K et al.:
DC-SIGN and Toll-like receptor 4 mediate oxidized low-density lipoprotein-induced inflammatory responses in macrophages
Sci Rep
2017
7: 3296
|
| 27496872 |
Nus M et al.:
Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis
|
| 26648562 |
Yin J et al.:
EGCG attenuates atherosclerosis through the Jagged-1/Notch pathway
Int. J. Mol. Med.
2016
37: 398-406
|
| 15196002 |
Kato T et al.:
Cystatin SA, a cysteine proteinase inhibitor, induces interferon-gamma expression in CD4-positive T cells
Biol. Chem.
2004
385: 419-422
|
| 18080843 |
Jia EZ et al.:
Association of the mutation for the human carboxypeptidase E gene exon 4 with the severity of coronary artery atherosclerosis
Mol. Biol. Rep.
2009
36: 245-254
|
| 27951653 |
Villarreal MM et al.:
Binding Properties of the Transforming Growth Factor-beta Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling
Biochemistry
2016
55: 6880-6896
|
| 22147696 |
Starr AE et al.:
Biochemical analysis of matrix metalloproteinase activation of chemokines CCL15 and CCL23 and increased glycosaminoglycan binding of CCL16
J. Biol. Chem.
2012
287: 5848-5860
|
| 25854545 |
Smith RM et al.:
Role of Peptide YY in blood vessel function and atherosclerosis in a rabbit model
Clin. Exp. Pharmacol. Physiol.
2015
42: 648-652
|
| 11701621 |
Mallat Z et al.:
Inhibition of transforming growth factor-beta signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice
Circ. Res.
2001
89: 930-934
|
| 10217353 |
Aviram M et al.:
Microsomal cytochromes P450 catalyze the oxidation of low density lipoprotein
Atherosclerosis
1999
143: 253-260
|
| 27091427 |
Lee GL et al.:
TLR4 induces CREB-mediated IL-6 production via upregulation of F-spondin to promote vascular smooth muscle cell migration
Biochem. Biophys. Res. Commun.
2016
473: 1205-1210
|
| 27996045 |
Hazell GG et al.:
PI16 is a shear stress and inflammation-regulated inhibitor of MMP2
Sci Rep
2016
6: 39553
|
| 24650549 |
Zhang P et al.:
Alkaline sphingomyelinase (NPP7) promotes cholesterol absorption by affecting sphingomyelin levels in the gut: A study with NPP7 knockout mice
Am. J. Physiol. Gastrointest. Liver Physiol.
2014
306: G903-G908
|
| 27496872 |
Nus M et al.:
Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis
Cardiovasc Res
2016
112: 568-580
|
| 15788404 |
Sakagami H et al.:
Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family
J. Biol. Chem.
2005
280
|
| 16255717 |
Wu J et al.:
Intestinal alkaline sphingomyelinase hydrolyses and inactivates platelet-activating factor by a phospholipase C activity
Biochem. J.
2006
394: 299-308
|
| 12885774 |
Duan RD et al.:
Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family
J. Biol. Chem.
2003
278
|
| 16690079 |
Leukert N et al.:
Calcium-dependent tetramer formation of S100A8 and S100A9 is essential for biological activity
J. Mol. Biol.
2006
4: 961-972
|
| 19772500 |
author information missing
[Comparative transcriptome analysis of human aorta atherosclerotic lesions and peripheral blood leukocytes from essential hypertension patients]
Kardiologiia
2009
49: 27-38
|
| 26091721 |
Vlaicu SI et al.:
The role of complement activation in atherogenesis: the first 40 years
Immunol Res
2016
64: 1-13
|
| 9157962 |
Frostegard J et al.:
Platelet-activating factor and oxidized LDL induce immune activation by a common mechanism
Arterioscler Thromb Vasc Biol
1997
17: 963-968
|
| 19075096 |
Oeseburg H et al.:
Bradykinin protects against oxidative stress-induced endothelial cell senescence
Hypertension
2009
53: 417-422
|
| 19289136 |
Jin Z et al.:
C-338A polymorphism of the endothelin-converting enzyme-1 gene and the susceptibility to carotid atherosclerosis
Microvasc. Res.
2009
78: 128-131
|
| 18997155 |
Martinez-Miguel P et al.:
Endothelin-converting enzyme-1 increases in atherosclerotic mice: potential role of oxidized low density lipoproteins
J. Lipid Res.
2009
50: 364-375
|
| 25978399 |
Ehlken C et al.:
Increased expression of angiogenic and inflammatory proteins in the vitreous of patients with ischemic central retinal vein occlusion
PLoS ONE
2015
10
|
| 27692470 |
Niyonzima N et al.:
Complement activation by cholesterol crystals triggers a subsequent cytokine response
Mol Immunol
2017
84: 43-50
|
| 23791966 |
Ortak H et al.:
Association of MMP2-1306C/T and TIMP2G-418C polymorphisms in retinal vein occlusion
Exp. Eye Res.
2013
113: 151-155
|
| 19520974 |
Ionita MG et al.:
High levels of myeloid-related protein 14 in human atherosclerotic plaques correlate with the characteristics of rupture-prone lesions
Arterioscler. Thromb. Vasc. Biol.
2009
29: 1220-1227
|
| 16216873 |
McCormick MM et al.:
S100A8 and S100A9 in human arterial wall. Implications for atherogenesis
J. Biol. Chem.
2005
280
|
| 22385834 |
Wang M et al.:
MFG-E8 activates proliferation of vascular smooth muscle cells via integrin signaling
Aging Cell
2012
11: 500-508
|
| 19443842 |
Fu Z et al.:
Milk fat globule protein epidermal growth factor-8: a pivotal relay element within the angiotensin II and monocyte chemoattractant protein-1 signaling cascade mediating vascular smooth muscle cells invasion
Circ. Res.
2009
104: 1337-1346
|
| 20405472 |
Lin YP et al.:
Comparative proteomic analysis of rat aorta in a subtotal nephrectomy model
Proteomics
2010
10: 2429-2443
|
| 9083074 |
Siegenthaler G et al.:
A heterocomplex formed by the calcium-binding proteins MRP8 (S100A8) and MRP14 (S100A9) binds unsaturated fatty acids with high affinity
J. Biol. Chem.
1997
272: 9371-9377
|
| 12036878 |
Ananyeva NM et al.:
Intrinsic pathway of blood coagulation contributes to thrombogenicity of atherosclerotic plaque
Blood
2002
99: 4475-4485
|
| 28570273 |
Wang Y et al.:
Myeloid-related protein-14 regulates deep vein thrombosis
|
| 27129300 |
Ishikawa T et al.:
The first EGF domain of coagulation factor IX attenuates cell adhesion and induces apoptosis
|
| 659613 |
author information missing
Activation of human factor IX (Christmas factor)
J. Clin. Invest.
1978
61: 1528-1538
|
| 9331959 |
Taran LD et al.:
Factor IX of the blood coagulation system: a review
Biochemistry Mosc.
1997
62: 685-693
|
| 15196915 |
Maceyka M et al.:
Aminoacylase 1 is a sphingosine kinase 1-interacting protein
FEBS Lett.
2004
568: 30-34
|
| 26125411 |
Habib A et al.:
Hepcidin-ferroportin axis controls toll-like receptor 4 dependent macrophage inflammatory responses in human atherosclerotic plaques
Atherosclerosis
2015
241: 692-700
|
| 26244503 |
Valenti L et al.:
Iron Stores, Hepcidin, and Aortic Stiffness in Individuals with Hypertension
PLoS ONE
2015
10
|
| 24334869 |
Galesloot TE et al.:
Serum hepcidin is associated with presence of plaque in postmenopausal women of a general population
Arterioscler. Thromb. Vasc. Biol.
2014
34: 446-456
|
| 22095982 |
Saeed O et al.:
Pharmacological suppression of hepcidin increases macrophage cholesterol efflux and reduces foam cell formation and atherosclerosis
Arterioscler. Thromb. Vasc. Biol.
2012
32: 299-307
|
| 24651679 |
Shaked I et al.:
Macrophage inflammatory markers are associated with subclinical carotid artery disease in women with human immunodeficiency virus or hepatitis C virus infection
Arterioscler. Thromb. Vasc. Biol.
2014
34: 1085-1092
|
| 25935004 |
Demerath EW et al.:
Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci
Hum. Mol. Genet.
2015
24: 4464-4479
|
| 25271210 |
Padilla J et al.:
Identification of genes whose expression is altered by obesity throughout the arterial tree
Physiol. Genomics
2014
46: 821-832
|
| 15231701 |
Grassadonia A et al.:
The 90K protein increases major histocompatibility complex class I expression and is regulated by hormones, gamma-interferon, and double-strand polynucleotides
Endocrinology
2004
145: 4728-4736
|
| 25288789 |
Traini M et al.:
Sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophages
J. Biol. Chem.
2014
289
|
| 19076828 |
Jylhava J et al.:
Genetics of C-reactive protein and complement factor H have an epistatic effect on carotid artery compliance: the Cardiovascular Risk in Young Finns Study
Clin Exp Immunol
2009
155: 53-58
|
| 15760767 |
Stetler-Stevenson WG et al.:
TIMP-2: an endogenous inhibitor of angiogenesis
Trends Mol Med
2005
11: 97-103
|
| 27127201 |
Li X et al.:
Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell Activation
Arterioscler. Thromb. Vasc. Biol.
2016
36: 1090-1100
|
| 25595536 |
Chistiakov DA et al.:
Myeloid dendritic cells: Development, functions, and role in atherosclerotic inflammation
Immunobiology
2015
220: 833-844
|
| 28069582 |
Li J et al.:
Human apolipoprotein A-I exerts a prophylactic effect on high-fat diet-induced atherosclerosis via inflammation inhibition in a rabbit model
Acta Biochim. Biophys. Sin. (Shanghai)
2017
49: 149-158
|
| 19307478 |
Gautier EL et al.:
Macrophage apoptosis exerts divergent effects on atherogenesis as a function of lesion stage
Circulation
2009
119: 1795-1804
|
| 24819748 |
Bertoia ML et al.:
Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease
Atherosclerosis
2014
235: 94-101
|
| 21810288 |
Charlton KE et al.:
Effect of 6 weeks consumption of beta-glucan-rich oat products on cholesterol levels in mildly hypercholesterolaemic overweight adults
Br. J. Nutr.
2012
107: 1037-1047
|
| 25411276 |
Whitehead A et al.:
Cholesterol-lowering effects of oat beta-glucan: a meta-analysis of randomized controlled trials
Am. J. Clin. Nutr.
2014
100: 1413-1421
|
| 23984330 |
El Rabey HA et al.:
Efficiency of barley bran and oat bran in ameliorating blood lipid profile and the adverse histological changes in hypercholesterolemic male rats
Biomed Res Int
2013
2013
|
| 21776394 |
Hansen JB et al.:
The apolipoprotein C-I content of very-low-density lipoproteins is associated with fasting triglycerides, postprandial lipemia, and carotid atherosclerosis
J Lipids
2011
2011
|
| 28473441 |
van Capelleveen JC et al.:
Apolipoprotein C-III Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study
Arterioscler. Thromb. Vasc. Biol.
2017
37: 1206-1212
|
| 21998749 |
Yang N et al.:
Apolipoprotein J: A New Predictor and Therapeutic Target in Cardiovascular Disease? }, authors { names std { { name ml Yang N }, { name ml Qin Q, affil str Department of Cardiology, Tianjin Chest Hospital, Tianjin 300222, China
Chin. Med. J.
2015
128: 2530-2534
|
| 19946382 |
author information missing
Apolipoprotein D in lipid metabolism and its functional implication in atherosclerosis and aging
Aging (Albany NY)
2009
1: 17-27
|
| 29248242 |
Cason CA et al.:
Plasma microbiome-modulated indole- and phenyl-derived metabolites associate with advanced atherosclerosis and postoperative outcomes
|
| 15905466 |
McNally JS et al.:
Regulation of xanthine oxidoreductase protein expression by hydrogen peroxide and calcium
Arterioscler. Thromb. Vasc. Biol.
2005
25: 1623-1628
|
| 27396856 |
Ryu HM et al.:
Hypoxanthine induces cholesterol accumulation and incites atherosclerosis in apolipoprotein E-deficient mice and cells
J. Cell. Mol. Med.
2016
20: 2160-2172
|
| 26604024 |
author information missing
Fatty acyl composition of lysophosphatidylcholine is important in atherosclerosis
Med. Hypotheses
2015
85: 754-760
|
| 29920190 |
Li F et al. et al.:
HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection
J. Clin. Invest.
2018
128: 4148-4162
|
| 23963755 |
Ma H et al.:
Increased atherosclerotic lesions in LDL receptor deficient mice with hematopoietic nuclear receptor Rev-erbalpha knock- down
J Am Heart Assoc
2013
2
|
| 29471141 |
Wesseling M et al.:
The morphological and molecular mechanisms of epithelial/endothelial-to-mesenchymal transition and its involvement in atherosclerosis
Vascul. Pharmacol.
2018
106: 1-8
|
| 14517540 |
Gretarsdottir S et al. et al.:
The gene encoding phosphodiesterase 4D confers risk of ischemic stroke
Nat. Genet.
2003
35: 131-138
|
| 20485444 |
Wang Y et al. et al.:
Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population
J. Hum. Genet.
2010
55: 490-494
|
| 21636130 |
Olivares-Navarrete R et al.:
Mediation of osteogenic differentiation of human mesenchymal stem cells on titanium surfaces by a Wnt-integrin feedback loop
Biomaterials
2011
32: 6399-6411
|
| 12818404 |
Hoy A et al.:
Myeloperoxidase polymorphisms in brain infarction. Association with infarct size and functional outcome
Atherosclerosis
2003
167: 223-230
|
| 28760743 |
Maier A et al.:
Hypoxia-inducible protein 2 Hig2/Hilpda mediates neutral lipid accumulation in macrophages and contributes to atherosclerosis in apolipoprotein E-deficient mice
FASEB J.
2017
31: 4971-4984
|
| 26571131 |
Lopez-Mejias R et al. et al.:
Protective Role of the Interleukin 33 rs3939286 Gene Polymorphism in the Development of Subclinical Atherosclerosis in Rheumatoid Arthritis Patients
PLoS ONE
2015
10
|
| 29844224 |
Loomis SJ et al. et al.:
Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study
Diabetes
2018
67: 1684-1696
|
| 24504735 |
Du F et al.:
MicroRNA-155 deficiency results in decreased macrophage inflammation and attenuated atherogenesis in apolipoprotein E-deficient mice
Arterioscler. Thromb. Vasc. Biol.
2014
34: 759-767
|
| 28128285 |
Sulkava M et al. et al.:
Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques - Tampere Vascular Study
Sci Rep
2017
7: 41483
|
| 20966410 |
Dong C et al.:
Genomewide linkage and peakwide association analyses of carotid plaque in Caribbean Hispanics
Stroke
2010
41: 2750-2756
|
| 30617313 |
Nehme A et al.:
Functional pathways associated with human carotid atheroma: a proteomics analysis
Hypertens. Res.
2019
42: 362-373
|
| 27470516 |
Perisic Matic L et al. et al.:
Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM
Arterioscler. Thromb. Vasc. Biol.
2016
36: 1947-1961
|
| 28607102 |
Haddad Y et al. et al.:
The Dendritic Cell Receptor DNGR-1 Promotes the Development of Atherosclerosis in Mice
Circ. Res.
2017
121: 234-243
|
| 20177342 |
Xu Y et al.:
Adenovirus-mediated overexpression of glutathione-s-transferase mitigates transplant arteriosclerosis in rabbit carotid allografts
Transplantation
2010
89: 409-416
|
| 28886156 |
Lietman CD et al.:
Loss of SPRR3 in ApoE-/- mice leads to atheroma vulnerability through Akt dependent and independent effects in VSMCs
PLoS ONE
2017
12
|
| 25278290 |
Segedy AK et al.:
Identification of small proline-rich repeat protein 3 as a novel atheroprotective factor that promotes adaptive Akt signaling in vascular smooth muscle cells
Arterioscler. Thromb. Vasc. Biol.
2014
34: 2527-2536
|
| 28487436 |
Brennan E et al. et al.:
Protective Effect of let-7 miRNA Family in Regulating Inflammation in Diabetes-Associated Atherosclerosis
Diabetes
2017
66: 2266-2277
|
| 12842993 |
Bijnens AP et al.:
Vasculin, a novel vascular protein differentially expressed in human atherogenesis
Blood
2003
102: 2803-2810
|
| 15258198 |
Elosua R et al.:
Association of APOE genotype with carotid atherosclerosis in men and women: the Framingham Heart Study
J. Lipid Res.
2004
45: 1868-1875
|
| 9407129 |
Srivastava RA et al.:
Estrogen up-regulates apolipoprotein E (ApoE) gene expression by increasing ApoE mRNA in the translating pool via the estrogen receptor alpha-mediated pathway
J. Biol. Chem.
1997
272
|
| 27540046 |
Schultheiss UT et al.:
Thyroid function, reduced kidney function and incident chronic kidney disease in a community-based population: the Atherosclerosis Risk in Communities study
Nephrol Dial Transplant
2017
32: 1874-1881
|
| 30046372 |
author information missing
article information missing
|
| 28051250 |
author information missing
article information missing
|
| 20411357 |
Wu SB et al.:
Mitochondrial DNA mutation-elicited oxidative stress, oxidative damage, and altered gene expression in cultured cells of patients with MERRF syndrome.
Mol. Neurobiol.
2010
41: 256-266
|
| 25559684 |
Catteruccia M et al.:
Myo-cardiomyopathy is commonly associated with the A8344G MERRF mutation
J. Neurol.
2015
262: 701-710
|
| 18587274 |
Choi BO et al.:
A MELAS syndrome family harboring two mutations in mitochondrial genome
Exp. Mol. Med.
2008
40: 354-360
|
| 15767514 |
Naini AB et al.:
Novel mitochondrial DNA ND5 mutation in a patient with clinical features of MELAS and MERRF
Arch. Neurol.
2005
62: 473-476
|
| 22285193 |
Gui C et al.:
Neuregulin-1/ErbB signaling is impaired in the rat model of diabetic cardiomyopathy
Cardiovasc. Pathol.
2012
21: 414-420
|
| 22524197 |
Zhang Y et al.:
Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: role of GSK3beta and mitochondrial function
BMC Med
2012
10: 40
|
| 20184888 |
Kruger M et al.:
Insulin signaling regulates cardiac titin properties in heart development and diabetic cardiomyopathy
J. Mol. Cell. Cardiol.
2010
48: 910-916
|
| 19367030 |
Sung PH et al.:
Impact of hyperglycemic control on left ventricular myocardium. A molecular and cellular basic study in a diabetic rat model
Int Heart J
2009
50: 191-206
|
| 17178726 |
Oestreich EA et al.:
Epac-mediated activation of phospholipase C(epsilon) plays a critical role in beta-adrenergic receptor-dependent enhancement of Ca2+ mobilization in cardiac myocytes
J. Biol. Chem.
2007
282: 5488-5495
|
| 10805403 |
Simko F et al.:
The potential role of nitric oxide in the hypertrophic growth of the left ventricle
Physiol Res
2000
49: 37-46
|
| 15931622 |
Ouslimani N et al.:
Metformin decreases intracellular production of reactive oxygen species in aortic endothelial cells
Metab. Clin. Exp.
2005
54: 829-834
|
| 17292717 |
Ouslimani N et al.:
Metformin reduces endothelial cell expression of both the receptor for advanced glycation end products and lectin-like oxidized receptor 1
Metab. Clin. Exp.
2007
56: 308-313
|
| 18177481 |
Zou MH et al.:
AMP-activated protein kinase activation as a strategy for protecting vascular endothelial function
Clin. Exp. Pharmacol. Physiol.
2008
35: 535-545
|
| 27230643 |
Shah MS et al.:
Molecular and Cellular Mechanisms of Cardiovascular Disorders in Diabetes
Circ Res
2016
118: 1808-1829
|
| 26470784 |
Ni R et al.:
Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy
Diabetes
2016
65: 255-268
|
| 26826429 |
Aloud BM et al.:
Conjugated linoleic acid prevents high glucose-induced hypertrophy and contractile dysfunction in adult rat cardiomyocytes
Nutr Res
2016
36: 134-142
|
| 28518143 |
Wang Y et al.:
Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway
Cell Death Dis
2017
8: e2799
|
| 27467007 |
Xu TJ et al.:
Insulin in combination with selenium inhibits HG/Pal-induced cardiomyocyte apoptosis by Cbl-b regulating p38MAPK/CBP/Ku70 pathway
Eur Rev Med Pharmacol Sci
2016
20: 3297-3303
|
| 20840849 |
author information missing
Rab4a signaling unmasks a pivotal link between myocardial homeostasis and metabolic remodeling in the diabetic heart
J. Mol. Cell. Cardiol.
2010
49: 908-910
|
| 30246236 |
Li H et al.:
Identification of biomarkers and mechanisms of diabetic cardiomyopathy using microarray data
|
| 29601906 |
Zhou H et al.:
Melatonin therapy for diabetic cardiomyopathy: A mechanism involving Syk-mitochondrial complex I-SERCA pathway
Cell. Signal.
2018
47: 88-100
|
| 28776188 |
Zhang X et al.:
Alterations of relaxin and its receptor system components in experimental diabetic cardiomyopathy rats
Cell Tissue Res.
2017
370: 297-304
|
| 31089754 |
Esser N et al.:
Neprilysin inhibition: a new therapeutic option for type 2 diabetes?
Diabetologia
2019
62: 1113-1122
|
| 30243718 |
Xu W et al.:
Fibroblast growth factor 19 improves cardiac function and mitochondrial energy homoeostasis in the diabetic heart
Biochem. Biophys. Res. Commun.
2018
505: 242-248
|
| 18296558 |
Singh VP et al.:
Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by high glucose: role in extracellular matrix production
Am J Physiol Heart Circ Physiol
2008
294
|
| 21444365 |
Harrison SC et al.:
Association of a sequence variant in DAB2IP with coronary heart disease
Eur. Heart J.
2012
33: 881-888
|
| 27112212 |
Shahid SU et al.:
Effect of SORT1, APOB and APOE polymorphisms on LDL-C and coronary heart disease in Pakistani subjects and their comparison with Northwick Park Heart Study II
Lipids Health Dis
2016
15: 83
|
| 12777472 |
Ezeh B et al.:
Plasma distribution of apoA-IV in patients with coronary artery disease and healthy controls
J. Lipid Res.
2003
44: 1523-1529
|
| 22572464 |
Dai W et al.:
Estradiol/Testosterone imbalance: impact on coronary heart disease risk factors in postmenopausal women
Cardiology
2012
121: 249-254
|
| 21687546 |
Zdravkovic V et al.:
Histamine blood concentration in ischemic heart disease patients
J. Biomed. Biotechnol.
2011
2011
|
| 21347282 |
Lettre G et al. et al.:
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project
PLoS Genet.
2011
7
|
| 32174839 |
Zhang Y et al.:
Low Level Antibodies Against Alpha-Tropomyosin Are Associated With Increased Risk of Coronary Heart Disease
Front Pharmacol
2020
11: 195
|
| 31501353 |
Huang R et al.:
MiR-31 promotes Th22 differentiation through targeting Bach2 in coronary heart disease
|
| 25474223 |
Liu YW et al.:
Elevated serum levels of soluble Axl in acute coronary syndrome
Am. J. Med. Sci.
2015
349: 124-129
|
| 23539218 |
Joehanes R et al. et al.:
Gene expression signatures of coronary heart disease
Arterioscler. Thromb. Vasc. Biol.
2013
33: 1418-1426
|
| 31475168 |
Han W et al.:
Alterations of irisin, adropin, preptin and BDNF concentrations in coronary heart disease patients comorbid with depression
Ann Transl Med
2019
7: 298
|
| 23583468 |
author information missing
article information missing
|
| 15657614 |
Blakely EL et al.:
LHON/MELAS overlap syndrome associated with a mitochondrial MTND1 gene mutation
Eur. J. Hum. Genet.
2005
13: 623-627
|
| 26095523 |
El-Hattab AW et al.:
MELAS syndrome: Clinical manifestations, pathogenesis, and treatment options
Mol. Genet. Metab.
2015
116: 4-12
|
| 19188198 |
Ware SM et al.:
Infantile cardiomyopathy caused by a mutation in the overlapping region of mitochondrial ATPase 6 and 8 genes
J. Med. Genet.
2009
46: 308-314
|
| 17954552 |
Jonckheere AI et al.:
A novel mitochondrial ATP8 gene mutation in a patient with apical hypertrophic cardiomyopathy and neuropathy
J. Med. Genet.
2008
45: 129-133
|
| 18089699 |
Langeveld M et al.:
Type I Gaucher disease, a glycosphingolipid storage disorder, is associated with insulin resistance
J. Clin. Endocrinol. Metab.
2008
93: 845-851
|
| 23266198 |
Yap TL et al.:
Membrane-bound alpha-synuclein interacts with glucocerebrosidase and inhibits enzyme activity
Mol. Genet. Metab.
2013
108: 56-64
|
| 22337770 |
Jovic M et al.:
Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, beta-glucocerebrosidase
Mol. Biol. Cell
2012
23: 1533-1545
|
| 22659419 |
Harzer K et al.:
Beta-glucosidase 1 (GBA1) is a second bile acid beta-glucosidase in addition to beta-glucosidase 2 (GBA2). Study in beta-glucosidase deficient mice and humans
Biochem. Biophys. Res. Commun.
2012
423: 308-312
|
| 15855349 |
Hearn T et al.:
Subcellular localization of ALMS1 supports involvement of centrosome and basal body dysfunction in the pathogenesis of obesity, insulin resistance, and type 2 diabetes
Diabetes
2005
54: 1581-1587
|
| 25299671 |
Favaretto F et al.:
GLUT4 defects in adipose tissue are early signs of metabolic alterations in Alms1GT/GT, a mouse model for obesity and insulin resistance
PLoS ONE
2014
9
|
| 17206865 |
author information missing
article information missing
|
| 22581473 |
author information missing
article information missing
|
| 26229500 |
author information missing
article information missing
|
| 22459206 |
Fletcher AL et al.:
Observations regarding retinopathy in mitochondrial trifunctional protein deficiencies
Mol. Genet. Metab.
2012
106: 18-24
|
| 27078015 |
Yonekawa Y et al.:
Ultra-Wide-Field Autofluorescence in Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency Chorioretinopathy
JAMA Ophthalmol
2016
134
|
| 23430524 |
Haglind CB et al.:
Growth in Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency
JIMD Rep
2013
8: 81-90
|
| 23395167 |
Singh R et al.:
LRP6 enhances glucose metabolism by promoting TCF7L2-dependent insulin receptor expression and IGF receptor stabilization in humans
Cell Metab.
2013
2: 197-209
|
| 12016587 |
Katsanis N et al.:
BBS4 is a minor contributor to Bardet-Biedl syndrome and may also participate in triallelic inheritance
Am. J. Hum. Genet.
2002
71: 22-29
|
| 26078953 |
Bee YM et al.:
Whole Exome Sequencing Identifies a Novel and a Recurrent Mutation in BBS2 Gene in a Family with Bardet-Biedl Syndrome
Biomed Res Int
2015
2015
|
| 16794820 |
Eichers ER et al.:
Phenotypic characterization of Bbs4 null mice reveals age-dependent penetrance and variable expressivity
Hum. Genet.
2006
120: 211-226
|
| 11381270 |
Mykytyn K et al.:
Identification of the gene that, when mutated, causes the human obesity syndrome BBS4
Nat. Genet.
2001
28: 188-191
|
| 15654695 |
Iannaccone A et al.:
Clinical evidence of decreased olfaction in Bardet-Biedl syndrome caused by a deletion in the BBS4 gene
Am. J. Med. Genet. A
2005
132A: 343-346
|
| 15107855 |
Kim JC et al.:
The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression
Nat. Genet.
2004
36: 462-470
|
| 17591906 |
Swiderski RE et al.:
Gene expression analysis of photoreceptor cell loss in bbs4-knockout mice reveals an early stress gene response and photoreceptor cell damage
Invest. Ophthalmol. Vis. Sci.
2007
48: 3329-3340
|
| 22219648 |
Wang H et al.:
Exome capture sequencing identifies a novel mutation in BBS4
Mol. Vis.
2011
17: 3529-3540
|
| 10973238 |
Slavotinek AM et al.:
Mutations in MKKS cause Bardet-Biedl syndrome
Nat. Genet.
2000
26: 15-16
|
| 22446187 |
author information missing
article information missing
|
| 15731008 |
author information missing
article information missing
|
| 25657044 |
Sofer S et al.:
The neuropsychological profile of patients with 3-methylglutaconic aciduria type III, Costeff syndrome
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2015
168B: 197-203
|
| 15654758 |
Lee J et al.:
Cultured gallbladder epithelial cells synthesize apolipoproteins A-I and E
Am. J. Physiol. Gastrointest. Liver Physiol.
2003
285: G630-G641
|
| 20835237 |
author information missing
article information missing
|
| 24722439 |
Airik R et al.:
Renal-retinal ciliopathy gene Sdccag8 regulates DNA damage response signaling
J. Am. Soc. Nephrol.
2014
25: 2573-2583
|
| 23793029 |
author information missing
article information missing
|
| 20169535 |
author information missing
article information missing
|
| 21565611 |
author information missing
article information missing
|
| 26540106 |
author information missing
article information missing
|
| 23446637 |
author information missing
article information missing
|
| 15723066 |
author information missing
article information missing
|
| 17617513 |
author information missing
article information missing
|
| 20690115 |
author information missing
article information missing
|
| 26487268 |
author information missing
article information missing
|
| 24674142 |
author information missing
article information missing
|
| 27625867 |
author information missing
article information missing
|
| 25635582 |
author information missing
article information missing
|
| 19118152 |
Hildebrandt F et al.:
Nephronophthisis: disease mechanisms of a ciliopathy
J. Am. Soc. Nephrol.
2009
20: 23-35
|
| 23348840 |
Tanos BE et al.:
Centriole distal appendages promote membrane docking, leading to cilia initiation
Genes Dev
2013
27: 163-168
|
| 15661758 |
author information missing
article information missing
|
| 24469809 |
author information missing
article information missing
|
| 23661805 |
author information missing
article information missing
|
| 25733456 |
author information missing
article information missing
|
| 26355001 |
author information missing
article information missing
|
| 34830133 |
author information missing
article information missing
|
| 19081074 |
Loktev AV et al.:
A BBSome subunit links ciliogenesis, microtubule stability, and acetylation
Dev. Cell
2008
15: 854-865
|
| 24026985 |
Scheidecker S et al.:
Exome sequencing of Bardet-Biedl syndrome patient identifies a null mutation in the BBSome subunit BBIP1 (BBS18)
J. Med. Genet.
2014
51: 132-136
|
| 25446516 |
Eguether T et al.:
IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment
Dev. Cell
2014
31: 279-290
|
| 25443296 |
Liew GM et al.:
The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3
Dev. Cell
2014
31: 265-278
|
| 24488770 |
Aldahmesh MA et al.:
IFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet-Biedl syndrome
Hum. Mol. Genet.
2014
23: 3307-3315
|
| 26023097 |
Yang N et al.:
Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis
Development
2015
142: 2194-2202
|
| 22072986 |
Seo S et al.:
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
PLoS Genet.
2011
7
|
| 22510444 |
Marion V et al.:
Exome sequencing identifies mutations in LZTFL1, a BBSome and smoothened trafficking regulator, in a family with Bardet--Biedl syndrome with situs inversus and insertional polydactyly
J. Med. Genet.
2012
49: 317-321
|
| 23692385 |
Schaefer E et al.:
Mesoaxial polydactyly is a major feature in Bardet-Biedl syndrome patients with LZTFL1 (BBS17) mutations
Clin. Genet.
2014
85: 476-481
|
| 22093827 |
Sakurai T et al.:
Involvement of leucine zipper transcription factor-like protein 1 (Lztfl1) in the attenuation of cognitive impairment by exercise training
Biochem. Biophys. Res. Commun.
2011
416: 125-129
|
| 17163542 |
Deffert C et al.:
Recurrent insertional polydactyly and situs inversus in a Bardet-Biedl syndrome family
Am. J. Med. Genet. A
2007
143A: 208-213
|
| 22626039 |
Billingsley G et al.:
Mutational analysis of SDCCAG8 in Bardet-Biedl syndrome patients with renal involvement and absent polydactyly
Ophthalmic Genet.
2012
33: 150-154
|
| 12559564 |
Kenedy AA et al.:
Identification and characterization of the novel centrosome-associated protein CCCAP
Gene
2003
303: 35-46
|
| 22095114 |
Scherag A et al.:
SDCCAG8 obesity alleles and reduced weight loss after a lifestyle intervention in overweight children and adolescents
Obesity (Silver Spring)
2012
20: 466-470
|
| 22190896 |
Schaefer E et al.:
Mutations in SDCCAG8/NPHP10 Cause Bardet-Biedl Syndrome and Are Associated with Penetrant Renal Disease and Absent Polydactyly
Mol Syndromol
2011
1: 273-281
|
| 22614287 |
Hamshere ML et al.:
Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC
Mol. Psychiatry
2013
18: 708-712
|
| 22825473 |
Patil H et al.:
Selective loss of RPGRIP1-dependent ciliary targeting of NPHP4, RPGR and SDCCAG8 underlies the degeneration of photoreceptor neurons
Cell Death Dis
2012
3: E355
|
| 22940612 |
Di Gioia SA et al.:
FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathies
Hum. Mol. Genet.
2012
21: 5174-5184
|
| 24157943 |
Divers J et al.:
Gene-gene interactions in APOL1-associated nephropathy
Nephrol. Dial. Transplant.
2014
29: 587-594
|
| 25088364 |
Insolera R et al.:
SDCCAG8 regulates pericentriolar material recruitment and neuronal migration in the developing cortex
Neuron
2014
83: 805-822
|
| 27224062 |
Airik R et al.:
SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling
PLoS ONE
2016
11
|
| 22863007 |
author information missing
article information missing
|
| 22940089 |
Cox KF et al.:
Phenotypic expression of Bardet-Biedl syndrome in patients homozygous for the common M390R mutation in the BBS1 gene
Vision Res.
2012
75: 77-87
|
| 23219996 |
Khan S et al.:
Novel homozygous mutations in the genes ARL6 and BBS10 underlying Bardet-Biedl syndrome
Gene
2013
515: 84-88
|
| 18203199 |
Hjortshoj TD et al.:
Novel mutations in BBS5 highlight the importance of this gene in non-Caucasian Bardet-Biedl syndrome patients
Am. J. Med. Genet. A
2008
146A: 517-520
|
| 19093007 |
Yang Z et al.:
A novel mutation in BBS7 gene causes Bardet-Biedl syndrome in a Chinese family
Mol. Vis.
2008
14: 2304-2308
|
| 16308660 |
Stoetzel C et al.:
BBS8 is rarely mutated in a cohort of 128 Bardet-Biedl syndrome families
J. Hum. Genet.
2006
51: 81-84
|
| 26846096 |
Khan MA et al.:
Homozygosity mapping identified a novel protein truncating mutation (p.Ser100Leufs*24) of the BBS9 gene in a consanguineous Pakistani family with Bardet Biedl syndrome
BMC Med. Genet.
2016
17: 10
|
| 16606853 |
Chiang AP et al.:
Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11)
Proc. Natl. Acad. Sci. U.S.A.
2006
103: 6287-6292
|
| 19349376 |
Locke M et al.:
TRIM32 is an E3 ubiquitin ligase for dysbindin
Hum. Mol. Genet.
2009
18: 2344-2358
|
| 24500717 |
Ramachandran H et al.:
Interaction with the Bardet-Biedl gene product TRIM32/BBS11 modifies the half-life and localization of Glis2/NPHP7
J. Biol. Chem.
2014
289: 8390-8401
|
| 24567360 |
Cohen S et al.:
Trim32 reduces PI3K-Akt-FoxO signaling in muscle atrophy by promoting plakoglobin-PI3K dissociation
J. Cell Biol.
2014
204: 747-758
|
| 26884348 |
Chen L et al.:
Tripartite motif 32 prevents pathological cardiac hypertrophy
Clin. Sci.
2016
130: 813-828
|
| 20648243 |
Pawlik B et al.:
A Novel Familial BBS12 Mutation Associated with a Mild Phenotype: Implications for Clinical and Molecular Diagnostic Strategies
Mol Syndromol
2010
1: 27-34
|
| 24608809 |
Xing DJ et al.:
Comprehensive molecular diagnosis of Bardet-Biedl syndrome by high-throughput targeted exome sequencing
PLoS ONE
2014
9
|
| 25552655 |
Barbelanne M et al.:
Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery
Hum. Mol. Genet.
2015
24: 2185-2200
|
| 18327255 |
Leitch CC et al.:
Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome
Nat. Genet.
2008
40: 443-448
|
| 24051377 |
author information missing
article information missing
|
| 24302887 |
Cui C et al.:
Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton
PLoS Biol.
2013
11
|
| 20671153 |
Kim SK et al.:
Planar cell polarity acts through septins to control collective cell movement and ciliogenesis
Science
2010
329: 1337-1340
|
| 24550735 |
Chamling X et al.:
The centriolar satellite protein AZI1 interacts with BBS4 and regulates ciliary trafficking of the BBSome
PLoS Genet.
2014
10
|
| 17574030 |
Nachury MV et al.:
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis
Cell
2007
129: 1201-1213
|
| 20603001 |
Jin H et al.:
The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia
Cell
2010
141: 1208-1219
|
| 22500027 |
Zhang Q et al.:
Intrinsic protein-protein interaction-mediated and chaperonin-assisted sequential assembly of stable bardet-biedl syndrome protein complex, the BBSome
J. Biol. Chem.
2012
287
|
| 20080638 |
Seo S et al.:
BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 1488-1493
|
| 27706820 |
Volta F et al.:
The role of primary cilia in obesity and diabetes
|
| 24961486 |
Yuan X et al.:
Function and regulation of primary cilia and intraflagellar transport proteins in the skeleton
Ann. N. Y. Acad. Sci.
2015
1335: 78-99
|
| 27385962 |
Suspitsin EN et al.:
Bardet-Biedl Syndrome
Mol Syndromol
2016
7: 62-71
|
| 27486776 |
Lindstrand A et al.:
Copy-Number Variation Contributes to the Mutational Load of Bardet-Biedl Syndrome
Am. J. Hum. Genet.
2016
99: 318-336
|
| 26854863 |
Khan AO et al.:
C8orf37 is mutated in Bardet-Biedl syndrome and constitutes a locus allelic to non-syndromic retinal dystrophies
Ophthalmic Genet.
2016
37: 290-293
|
| 27008867 |
Heon E et al.:
Mutations in C8ORF37 cause Bardet Biedl syndrome (BBS21)
|
| 22177090 |
Estrada-Cuzcano A et al.:
Mutations in C8orf37, encoding a ciliary protein, are associated with autosomal-recessive retinal dystrophies with early macular involvement
Am. J. Hum. Genet.
2012
90: 102-109
|
| 26103456 |
Starks RD et al.:
Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins
PLoS Genet.
2015
11
|
| 26763875 |
author information missing
article information missing
|
| 19150989 |
author information missing
article information missing
|
| 22179047 |
author information missing
article information missing
|
| 30287585 |
author information missing
article information missing
|
| 34573333 |
author information missing
article information missing
|
| 34440435 |
author information missing
article information missing
|
| 30573563 |
author information missing
article information missing
|
| 22842230 |
author information missing
article information missing
|
| 33107823 |
author information missing
article information missing
|
| 26912414 |
author information missing
article information missing
|
| 8944027 |
author information missing
article information missing
|
| 21928830 |
author information missing
article information missing
|
| 21078983 |
author information missing
article information missing
|
| 9326927 |
author information missing
article information missing
|
| 16116091 |
author information missing
article information missing
|
| 28874556 |
author information missing
article information missing
|
| 20100834 |
author information missing
article information missing
|
| 20356843 |
author information missing
article information missing
|
| 29899041 |
author information missing
article information missing
|
| 25398945 |
author information missing
article information missing
|
| 21310915 |
author information missing
article information missing
|
| 19268277 |
author information missing
article information missing
|
| 10873396 |
author information missing
article information missing
|
| 12374762 |
author information missing
article information missing
|
| 33067476 |
author information missing
article information missing
|
| 18408180 |
author information missing
article information missing
|
| 27268253 |
author information missing
article information missing
|
| 15365178 |
author information missing
article information missing
|
| 19758987 |
author information missing
article information missing
|
| 25799540 |
author information missing
article information missing
|
| 24108108 |
author information missing
article information missing
|
| 14555765 |
author information missing
article information missing
|
| 21606596 |
author information missing
article information missing
|
| 17546029 |
author information missing
article information missing
|
| 27067258 |
author information missing
article information missing
|
| 21850168 |
author information missing
article information missing
|
| 19503738 |
author information missing
article information missing
|
| 11283794 |
author information missing
article information missing
|
| 12920076 |
author information missing
article information missing
|
| 11528500 |
author information missing
article information missing
|
| 19679561 |
author information missing
article information missing
|
| 31666973 |
author information missing
article information missing
|
| 12651948 |
author information missing
article information missing
|
| 9537410 |
author information missing
article information missing
|
| 9931337 |
author information missing
article information missing
|
| 10887186 |
author information missing
article information missing
|
| 10708567 |
author information missing
article information missing
|
| 17920587 |
author information missing
article information missing
|
| 15914641 |
author information missing
article information missing
|
| 12915475 |
author information missing
article information missing
|
| 15316081 |
author information missing
article information missing
|
| 28445802 |
author information missing
article information missing
|
| 27735788 |
author information missing
article information missing
|
| 35191957 |
author information missing
article information missing
|
| 32254022 |
author information missing
article information missing
|
| 34537244 |
author information missing
article information missing
|
| 31980596 |
author information missing
article information missing
|
| 25477517 |
author information missing
article information missing
|
| 24904271 |
author information missing
article information missing
|
| 22531706 |
author information missing
article information missing
|
| 17186464 |
author information missing
article information missing
|
| 23308101 |
author information missing
article information missing
|
| 15322982 |
author information missing
article information missing
|
| 15258582 |
author information missing
article information missing
|
| 35491887 |
author information missing
article information missing
|
| 34445569 |
author information missing
article information missing
|
| 11381255 |
author information missing
article information missing
|
| 17011878 |
author information missing
article information missing
|
| 18055821 |
author information missing
article information missing
|
| 34836244 |
author information missing
article information missing
|
| 33631212 |
author information missing
article information missing
|
| 30967641 |
author information missing
article information missing
|
| 30914787 |
author information missing
article information missing
|
| 30115683 |
author information missing
article information missing
|
| 24036882 |
author information missing
article information missing
|
| 15024725 |
author information missing
article information missing
|
| 34360830 |
author information missing
article information missing
|
| 30950243 |
author information missing
article information missing
|
| 26987071 |
author information missing
article information missing
|
| 25921210 |
author information missing
article information missing
|
| 25475713 |
author information missing
article information missing
|
| 32437550 |
author information missing
article information missing
|
| 31647904 |
author information missing
article information missing
|
| 30257863 |
author information missing
article information missing
|
| 28878288 |
author information missing
article information missing
|
| 27203561 |
author information missing
article information missing
|
| 23307924 |
author information missing
article information missing
|
| 35240325 |
author information missing
article information missing
|
| 34021019 |
author information missing
article information missing
|
| 29198720 |
author information missing
article information missing
|
| 22819833 |
author information missing
article information missing
|
| 28721681 |
Ali MU et al.:
Genetic characterization and disease mechanism of retinitis pigmentosa; current scenario
3 Biotech
3 Bi
7: 251
|
| 20705279 |
Bandah-Rozenfeld D et al.:
Homozygosity mapping reveals null mutations in FAM161A as a cause of autosomal-recessive retinitis pigmentosa
Am. J. Hum. Genet.
2010
87: 382-391
|
| 20705278 |
Langmann T et al. et al.:
Nonsense mutations in FAM161A cause RP28-associated recessive retinitis pigmentosa
Am. J. Hum. Genet.
2010
87: 376-381
|
| 32211407 |
Gao ML et al.:
Patient-Specific Retinal Organoids Recapitulate Disease Features of Late-Onset Retinitis Pigmentosa
Front Cell Dev Biol
2020
8: 128
|
| 29272204 |
Owen EJ et al.:
Pharmacokinetics and Pharmacodynamics of Antimicrobials in Critically Ill Patients
Surg Infect (Larchmt)
2018
19: 155-162
|
| 21078119 |
Kim JW et al.:
Neural retina leucine-zipper regulates the expression of Ppp2r5c, the regulatory subunit of protein phosphatase 2A, in photoreceptor development
FEBS J
2010
277: 5051-5060
|
| 10775529 |
Rivolta C et al.:
Missense mutation in the USH2A gene: association with recessive retinitis pigmentosa without hearing loss
Am J Hum Genet
2000
66: 1975-1978
|
| 22619378 |
author information missing
article information missing
|
| 26964041 |
author information missing
article information missing
|
| 11847227 |
author information missing
article information missing
|
| 18588884 |
author information missing
article information missing
|
| 11875050 |
author information missing
article information missing
|
| 24618324 |
author information missing
article information missing
|
| 19140180 |
author information missing
article information missing
|
| 18779497 |
author information missing
article information missing
|
| 9462750 |
author information missing
article information missing
|
| 9462751 |
author information missing
article information missing
|
| 15557452 |
author information missing
article information missing
|
| 17620573 |
author information missing
article information missing
|
| 33907372 |
author information missing
article information missing
|
| 27440997 |
author information missing
article information missing
|
| 22665969 |
author information missing
article information missing
|
| 1749427 |
author information missing
article information missing
|
| 1684223 |
author information missing
article information missing
|
| 10739664 |
author information missing
article information missing
|
| 11493697 |
author information missing
article information missing
|
| 16885411 |
author information missing
article information missing
|
| 16308564 |
author information missing
article information missing
|
| 18477472 |
author information missing
article information missing
|
| 12872123 |
author information missing
article information missing
|
| 12471060 |
author information missing
article information missing
|
| 15852005 |
author information missing
article information missing
|
| 24026243 |
author information missing
article information missing
|
| 27220846 |
author information missing
article information missing
|
| 12221118 |
author information missing
article information missing
|
| 18371931 |
author information missing
article information missing
|
| 12872122 |
author information missing
article information missing
|
| 12244321 |
author information missing
article information missing
|
| 22654112 |
author information missing
article information missing
|
| 25100726 |
author information missing
article information missing
|
| 21555462 |
author information missing
article information missing
|
| 16326862 |
author information missing
article information missing
|
| 17289029 |
author information missing
article information missing
|
| 17618285 |
author information missing
article information missing
|
| 26374130 |
author information missing
article information missing
|
| 26083374 |
author information missing
article information missing
|
| 21127075 |
author information missing
article information missing
|
| 17344476 |
author information missing
article information missing
|
| 21816948 |
author information missing
article information missing
|
| 22391303 |
author information missing
article information missing
|
| 20865670 |
author information missing
article information missing
|
| 18235101 |
author information missing
article information missing
|
| 17928412 |
author information missing
article information missing
|
| 26967905 |
author information missing
article information missing
|
| 25599650 |
author information missing
article information missing
|
| 23973373 |
author information missing
article information missing
|
| 23418306 |
author information missing
article information missing
|
| 22106379 |
author information missing
article information missing
|
| 23026745 |
author information missing
article information missing
|
| 26035863 |
author information missing
article information missing
|
| 23456819 |
author information missing
article information missing
|
| 19732765 |
author information missing
article information missing
|
| 27482817 |
author information missing
article information missing
|
| 18327258 |
author information missing
article information missing
|
| 24876116 |
author information missing
article information missing
|
| 22689656 |
author information missing
article information missing
|
| 27727273 |
author information missing
article information missing
|
| 24982133 |
author information missing
article information missing
|
| 25340510 |
author information missing
article information missing
|
| 26966185 |
author information missing
article information missing
|
| 25297623 |
author information missing
article information missing
|
| 23955340 |
author information missing
article information missing
|
| 26327442 |
author information missing
article information missing
|
| 22701722 |
author information missing
article information missing
|
| 20856870 |
Wodarczyk C et al. et al.:
Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals
PLoS One
2010
5
|
| 16682973 |
author information missing
article information missing
|
| 17558409 |
author information missing
article information missing
|
| 17558407 |
author information missing
article information missing
|
| 23683095 |
author information missing
article information missing
|
| 21945076 |
author information missing
article information missing
|
| 20391533 |
author information missing
article information missing
|
| 21725307 |
author information missing
article information missing
|
| 27765513 |
author information missing
article information missing
|
| 23870701 |
author information missing
article information missing
|
| 23150559 |
author information missing
article information missing
|
| 24166846 |
author information missing
article information missing
|
| 27927754 |
author information missing
article information missing
|
| 28172980 |
author information missing
article information missing
|
| 26490104 |
author information missing
article information missing
|
| 25103236 |
author information missing
article information missing
|
| 24613594 |
author information missing
article information missing
|
| 21289087 |
Lai CK et al.:
Functional characterization of putative cilia genes by high-content analysis
Mol. Biol. Cell
2011
22: 1104-1119
|
| 28102635 |
author information missing
article information missing
|
| 22282472 |
author information missing
article information missing
|
| 27245168 |
author information missing
article information missing
|
| 26714646 |
author information missing
article information missing
|
| 29695797 |
author information missing
article information missing
|
| 30858804 |
author information missing
article information missing
|
| 34241634 |
author information missing
article information missing
|
| 19800048 |
author information missing
article information missing
|
| 25644602 |
author information missing
article information missing
|
| 21633164 |
author information missing
article information missing
|
| 26477546 |
author information missing
article information missing
|
| 22425360 |
author information missing
article information missing
|
| 23012439 |
author information missing
article information missing
|
| 26096313 |
author information missing
article information missing
|
| 24886560 |
author information missing
article information missing
|
| 32453716 |
author information missing
article information missing
|
| 27208211 |
author information missing
article information missing
|
| 26092869 |
author information missing
article information missing
|
| 30905400 |
author information missing
article information missing
|
| 23349226 |
author information missing
article information missing
|
| 21462283 |
author information missing
article information missing
|
| 21493627 |
author information missing
article information missing
|
| 16415886 |
author information missing
article information missing
|
| 22121117 |
author information missing
article information missing
|
| 17185389 |
author information missing
article information missing
|
| 26123494 |
author information missing
article information missing
|
| 21763481 |
author information missing
article information missing
|
| 24322779 |
author information missing
article information missing
|
| 32348467 |
author information missing
article information missing
|
| 24128419 |
author information missing
article information missing
|
| 24947469 |
author information missing
article information missing
|
| 23530209 |
author information missing
article information missing
|
| 25557784 |
author information missing
article information missing
|
| 21698230 |
author information missing
article information missing
|
| 19668215 |
author information missing
article information missing
|
| 25269936 |
author information missing
article information missing
|
| 25395580 |
author information missing
article information missing
|
| 28031327 |
author information missing
article information missing
|
| 27998989 |
author information missing
article information missing
|
| 27056978 |
author information missing
article information missing
|
| 26916822 |
author information missing
article information missing
|
| 20036350 |
author information missing
article information missing
|
| 20512146 |
author information missing
article information missing
|
| 18633336 |
author information missing
article information missing
|
| 23532844 |
author information missing
article information missing
|
| 19625297 |
author information missing
article information missing
|
| 20592197 |
author information missing
article information missing
|
| 18674751 |
author information missing
article information missing
|
| 24360808 |
author information missing
article information missing
|
| 24061448 |
Vethe NT et al.:
Simultaneous quantification of IMPDH activity and purine bases in lymphocytes using LC-MS/MS: assessment of biomarker responses to mycophenolic acid
Ther Drug Monit
2014
36: 108-118
|
| 23236438 |
Thomas EC et al.:
Different characteristics and nucleotide binding properties of inosine monophosphate dehydrogenase (IMPDH) isoforms
PLoS ONE
2012
7
|
| 16384941 |
Bowne SJ et al.:
Spectrum and frequency of mutations in IMPDH1 associated with autosomal dominant retinitis pigmentosa and leber congenital amaurosis
Invest. Ophthalmol. Vis. Sci.
2006
47: 34-42
|
| 14766016 |
McLean JE et al.:
Inosine 5-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo
Biochem. J.
2004
379: 243-251
|
| 19480389 |
Hedstrom L et al.:
IMP dehydrogenase: structure, mechanism, and inhibition
Chem. Rev.
2009
109: 2903-2928
|
| 16936083 |
Bowne SJ et al.:
Why do mutations in the ubiquitously expressed housekeeping gene IMPDH1 cause retina-specific photoreceptor degeneration
Invest. Ophthalmol. Vis. Sci.
2006
47: 3754-3765
|
| 18974094 |
Mortimer SE et al.:
IMP dehydrogenase type 1 associates with polyribosomes translating rhodopsin mRNA
J. Biol. Chem.
2008
283
|
| 18295591 |
Xu D et al.:
Retinal isoforms of inosine 5-monophosphate dehydrogenase type 1 are poor nucleic acid binding proteins
Arch. Biochem. Biophys.
2008
472: 100-104
|
| 15882147 |
Mortimer SE et al.:
Autosomal dominant retinitis pigmentosa mutations in inosine 5-monophosphate dehydrogenase type I disrupt nucleic acid binding
Biochem. J.
2005
390: 41-47
|
| 26720483 |
Coussa RG et al. et al.:
Genotype and Phenotype Studies in Autosomal Dominant Retinitis Pigmentosa (adRP) of the French Canadian Founder Population
Invest. Ophthalmol. Vis. Sci.
2015
56: 8297-8305
|
| 29946345 |
Keppeke GD et al.:
IMP/GTP balance modulates cytoophidium assembly and IMPDH activity
Cell Div
2018
13: 5
|
| 24940031 |
Pan X et al.:
Mutation analysis of pre-mRNA splicing genes in Chinese families with retinitis pigmentosa
Mol. Vis.
2014
20: 770-779
|
| 26303200 |
Chang CC et al.:
Cytoophidium assembly reflects upregulation of IMPDH activity
J. Cell. Sci.
2015
128: 3550-3555
|
| 26558346 |
Buey RM et al.:
Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases
Nat Commun
2015
6: 8923
|
| 21763485 |
Sergouniotis PI et al.:
Recessive mutations in KCNJ13, encoding an inwardly rectifying potassium channel subunit, cause leber congenital amaurosis
Am. J. Hum. Genet.
2011
89: 183-190
|
| 20946626 |
Novarino G et al.:
Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis
Science
2010
328: 1398-1401
|
| 9430698 |
Zhang X et al.:
Cell lines from kidney proximal tubules of a patient with Lowe syndrome lack OCRL inositol polyphosphate 5-phosphatase and accumulate phosphatidylinositol 4,5-bisphosphate
J. Biol. Chem.
1998
273: 1574-1582
|
| 25168386 |
Bujakowska KM et al. et al.:
Mutations in IFT172 cause isolated retinal degeneration and Bardet-Biedl syndrome
Hum. Mol. Genet.
2015
24: 230-242
|
| 24140113 |
Halbritter J et al. et al.:
Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans
Am. J. Hum. Genet.
2013
93: 915-925
|
| 25367221 |
author information missing
article information missing
|
| 26643951 |
author information missing
article information missing
|
| 19273592 |
author information missing
article information missing
|
| 24525530 |
author information missing
article information missing
|
| 20179356 |
author information missing
article information missing
|
| 25609706 |
author information missing
article information missing
|
| 20503175 |
Rattner JB et al.:
Primary cilia in fibroblast-like type B synoviocytes lie within a cilium pit: a site of endocytosis
Histol Histopathol
2010
25: 865-875
|
| 23805271 |
Luo N et al.:
Compensatory Role of Inositol 5-Phosphatase INPP5B to OCRL in Primary Cilia Formation in Oculocerebrorenal Syndrome of Lowe
PLoS ONE
2013
8
|
| 22072788 |
Bohdanowicz M et al.:
Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling
Mol. Biol. Cell
2012
23: 176-187
|
| 15474001 |
Schmid AC et al.:
Type II phosphoinositide 5-phosphatases have unique sensitivities towards fatty acid composition and head group phosphorylation
FEBS Lett.
2004
576: 9-13
|
| 9566967 |
Murphy SM et al.:
The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components spc97p and spc98p
J. Cell Biol.
1998
3: 663-674
|
| 11694571 |
Murphy SM et al.:
GCP5 and GCP6: two new members of the human gamma-tubulin complex
Mol. Biol. Cell
2001
11: 3340-3352
|
| 24972650 |
Balasubramaniam S et al.:
Inborn errors of purine metabolism: clinical update and therapies
J. Inherit. Metab. Dis.
2014
37: 669-686
|
| 23643948 |
Labesse G et al.:
MgATP regulates allostery and fiber formation in IMPDHs
Structure
2013
21: 975-985
|
| 14643120 |
Miyamoto T et al.:
Azoospermia in patients heterozygous for a mutation in SYCP3
Lancet
2003
362: 1714-1719
|
| 27666822 |
Duran I et al.:
Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome
Sci Rep
2016
6: 34232
|
| 23261302 |
Knowles MR et al. et al.:
Exome sequencing identifies mutations in CCDC114 as a cause of primary ciliary dyskinesia
Am. J. Hum. Genet.
2013
92: 99-106
|
| 23261303 |
Onoufriadis A et al. et al.:
Splice-site mutations in the axonemal outer dynein arm docking complex gene CCDC114 cause primary ciliary dyskinesia
Am. J. Hum. Genet.
2013
92: 88-98
|
| 25802884 |
Fedick AM et al.:
Carrier frequencies of eleven mutations in eight genes associated with primary ciliary dyskinesia in the Ashkenazi Jewish population
Mol Genet Genomic Med
2015
3: 137-142
|
| 28965847 |
De Mori R et al. et al.:
Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects
Am. J. Hum. Genet.
2017
101: 552-563
|
| 26275418 |
Perrault I et al. et al.:
IFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype
J. Med. Genet.
2015
52: 657-665
|
| 31554934 |
Martin-Hurtado A et al.:
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling
Sci Rep
2019
9: 13896
|
| 29198720 |
Luscan R et al. et al.:
Mutations in TUBB4B Cause a Distinctive Sensorineural Disease
Am. J. Hum. Genet.
2017
101: 1006-1012
|
| 29463826 |
Ott C et al.:
VPS4 is a dynamic component of the centrosome that regulates centrosome localization of gamma-tubulin, centriolar satellite stability and ciliogenesis
Sci Rep
2018
8: 3353
|
| 17847006 |
Dam AH et al.:
Homozygous mutation in SPATA16 is associated with male infertility in human globozoospermia
Am. J. Hum. Genet.
2007
81: 813-820
|
| 10794082 |
Di Carlo AD et al.:
The meiotic specific synaptonemal complex protein SCP3 is expressed by female and male primordial germ cells of the mouse embryo
Int. J. Dev. Biol.
2000
44: 241-244
|
| 8289794 |
Lammers JH et al.:
The gene encoding a major component of the lateral elements of synaptonemal complexes of the rat is related to X-linked lymphocyte-regulated genes
Mol. Cell. Biol.
1994
14: 1137-1146
|
| 27997882 |
Geisinger A et al.:
Mutations in Genes Coding for Synaptonemal Complex Proteins and Their Impact on Human Fertility
Cytogenet. Genome Res.
2016
150: 77-85
|
| 25927852 |
Imtiaz F et al.:
Variation in DNAH1 may contribute to primary ciliary dyskinesia
BMC Med. Genet.
2015
16: 14
|
| 24360805 |
Ben Khelifa M et al. et al.:
Mutations in DNAH1, which encodes an inner arm heavy chain dynein, lead to male infertility from multiple morphological abnormalities of the sperm flagella
Am. J. Hum. Genet.
2014
94: 95-104
|
| 9373155 |
Neesen J et al.:
Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene
Gene
1997
200: 193-202
|
| 28659385 |
Mojarad BA et al.:
CEP19 cooperates with FOP and CEP350 to drive early steps in the ciliogenesis programme
|
| 30561330 |
Huizar RL et al.:
A liquid-like organelle at the root of motile ciliopathy
|
| 24559376 |
Al-Hamed MH et al.:
Functional modelling of a novel mutation in BBS5
Cilia
2014
3: 3
|
| 23907739 |
Nozawa YI et al.:
Fused (Stk36) is a ciliary protein required for central pair assembly and motile cilia orientation in the mammalian oviduct
Dev. Dyn.
2013
242: 1307-1319
|
| 18600476 |
Maloveryan A et al.:
A possible role of mouse Fused (STK36) in Hedgehog signaling and Gli transcription factor regulation
J Cell Commun Signal
2007
1: 165-173
|
| 28543983 |
Edelbusch C et al.:
Mutation of serine/threonine protein kinase 36 (STK36) causes primary ciliary dyskinesia with a central pair defect
Hum. Mutat.
2017
38: 964-969
|
| 27488028 |
Chen J et al. et al.:
Deficiency of SPATA46, a Novel Nuclear Membrane Protein, Causes Subfertility in Male Mice
Biol. Reprod.
2016
95: 58
|
| 28625779 |
Potter C et al.:
Multiple Isoforms of Nesprin1 Are Integral Components of Ciliary Rootlets
Curr. Biol.
2017
27: 2014-2022.e6
|
| 31723061 |
Tsai IC et al.:
Genome-wide suppressor screen identifies USP35/USP38 as therapeutic candidates for ciliopathies
|
| 17906624 |
Gerdes JM et al.:
Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response
Nat. Genet.
2007
39: 1350-1360
|
| 27104747 |
Guen VJ et al.:
STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis
Cell Cycle
2016
15: 678-688
|
| 32604881 |
Lai Y et al.:
Reciprocal Regulation between Primary Cilia and mTORC1
|
| 30300884 |
Sun DI et al.:
Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia
Cells Tissues Organs (Print)
2018
205: 279-292
|
| 30497210 |
Rubino S et al.:
A familial syndrome of hypothalamic hamartomas, polydactyly, and SMO mutations: a clinical report of 2 cases
J Neurosurg Pediatr
2018
23: 98-103
|
| 24861006 |
diIorio P et al.:
Role of cilia in normal pancreas function and in diseased states
Birth Defects Res. C Embryo Today
2014
102: 126-138
|
| 11571556 |
Bouba I et al.:
Novel PKD1 deletions and missense variants in a cohort of Hellenic polycystic kidney disease families
Eur J Hum Genet
2001
9: 677-684
|
| 12514735 |
Nauli SM et al.:
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
Nat Genet
2003
33: 129-137
|
| 8650545 |
Mochizuki T et al. et al.:
PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein
Science
1996
272: 1339-1342
|
| 27259053 |
Porath B et al. et al.:
Mutations in GANAB, Encoding the Glucosidase IIalpha Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease
Am J Hum Genet
2016
98: 1193-1207
|
| 11919560 |
Ward CJ et al. et al.:
The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein
Nat Genet
2002
30: 259-269
|
| 14983006 |
Zhang MZ et al. et al.:
PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells
Proc Natl Acad Sci U S A
2004
101: 2311-2316
|
| 28530676 |
Lu H et al. et al.:
Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease
Nat Genet
2017
49: 1025-1034
|
| 30915099 |
Wheway G et al.:
Opportunities and Challenges for Molecular Understanding of Ciliopathies-The 100,000 Genomes Project
Front Genet
2019
10: 127
|
| 23742838 |
Botilde Y et al.:
Cluap1 localizes preferentially to the base and tip of cilia and is required for ciliogenesis in the mouse embryo
Dev Biol
2013
381: 203-212
|
| 30988386 |
Tsai JJ et al.:
CEP120 interacts with C2CD3 and Talpid3 and is required for centriole appendage assembly and ciliogenesis
Sci Rep
2019
9: 6037
|
| 28625504 |
Van De Weghe JC et al. et al.:
Mutations in ARMC9, which Encodes a Basal Body Protein, Cause Joubert Syndrome in Humans and Ciliopathy Phenotypes in Zebrafish
Am J Hum Genet
2017
101: 23-36
|
| 25877302 |
Damerla RR et al. et al.:
Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies
Hum Mol Genet
2015
24: 3994-4005
|
| 30269812 |
Alkanderi S et al. et al.:
ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition
Am J Hum Genet
2018
103: 612-620
|
| 23970417 |
Satish Tammana TV et al.:
Centrosomal protein CEP104 (Chlamydomonas FAP256) moves to the ciliary tip during ciliary assembly
J Cell Sci
2013
126: 5018-5029
|
| 22246503 |
Lee JE et al. et al.:
CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium
Nat Genet
2012
44: 193-199
|
| 21131972 |
Merveille AC et al. et al.:
CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs
Nat Genet
2011
43: 72-78
|
| 8840269 |
Schaefer L et al.:
Alterations of cathepsins B, H and L in proximal tubules from polycystic kidneys of the Han:SPRD rat
Kidney Int
1996
50: 424-431
|
| 30467237 |
Uddin B et al.:
The human phosphatase CDC14A modulates primary cilium length by regulating centrosomal actin nucleation
|
| 29771182 |
Liu ZQ et al.:
Ciliogenesis is reciprocally regulated by PPARA and NR1H4/FXR through controlling autophagy in vitro and in vivo
Autophagy
2018
14: 1011-1027
|
| 30793219 |
Horikawa Y et al.:
Genetic Dissection and Clinical Features of MODY6 (NEUROD1-MODY)
Curr Diab Rep
2019
19: 12
|
| 32233951 |
Qu W et al. et al.:
The essential role of intraflagellar transport protein IFT81 in male mice spermiogenesis and fertility
Am J Physiol Cell Physiol
2020
318
|
| 32783357 |
Ashraf T et al.:
Expanding the phenotypic spectrum of IFT81: Associated ciliopathy syndrome
Am J Med Genet A
2020
182: 2403-2408
|
| 33382037 |
Moon KH et al.:
Dysregulation of sonic hedgehog signaling causes hearing loss in ciliopathy mouse models
|
| 25224326 |
Alsaadi MM et al.:
Nonsense mutation in coiled-coil domain containing 151 gene (CCDC151) causes primary ciliary dyskinesia
Hum Mutat
2014
35: 1446-1448
|
| 24067530 |
Jerber J et al.:
The coiled-coil domain containing protein CCDC151 is required for the function of IFT-dependent motile cilia in animals
Hum Mol Genet
2014
23: 563-577
|
| 25192045 |
Hjeij R et al. et al.:
CCDC151 mutations cause primary ciliary dyskinesia by disruption of the outer dynein arm docking complex formation
Am J Hum Genet
2014
95: 257-274
|
| 31383820 |
Chiani F et al.:
Functional loss of Ccdc1 51 leads to hydrocephalus in a mouse model of primary ciliary dyskinesia
|
| 32286033 |
Abu Hanna F et al.:
Intrafamilial Phenotypic Variability in Two Siblings with Primary Ciliary Dyskinesia Due to Homozygous Loss of Function Mutation in the CCDC151 Gene
Isr Med Assoc J
2020
22: 260-262
|
| 27173435 |
Boldt K et al. et al.:
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
Nat Commun
2016
7: 11491
|
| 31934493 |
Suzuki A et al.:
Disruption of Dhcr7 and Insig1/2 in cholesterol metabolism causes defects in bone formation and homeostasis through primary cilium formation
Bone Res
2020
8: 1
|
| 31006513 |
De Franco E et al. et al.:
A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development
Am J Hum Genet
2019
104: 985-989
|
| 31006510 |
Kruszka P et al.:
A CCR4-NOT Transcription Complex, Subunit 1, CNOT1, Variant Associated with Holoprosencephaly
Am J Hum Genet
2019
104: 990-993
|
| 26378583 |
Falk N et al.:
Specialized Cilia in Mammalian Sensory Systems
Cells
2015
4: 500-519
|
| 22855724 |
Wu DK et al.:
Molecular mechanisms of inner ear development
Cold Spring Harb Perspect Biol
2012
4
|
| 33920085 |
de Joya EM et al.:
Usher Syndrome in the Inner Ear: Etiologies and Advances in Gene Therapy
|
| 9171832 |
Liu XZ et al.:
Mutations in the myosin VIIA gene cause non-syndromic recessive deafness
Nat Genet
1997
16: 188-190
|
| 9171833 |
Weil D et al.:
The autosomal recessive isolated deafness, DFNB2, and the Usher 1B syndrome are allelic defects of the myosin-VIIA gene
Nat Genet
1997
16: 191-193
|
| 20016096 |
Schwander M et al.:
A novel allele of myosin VIIa reveals a critical function for the C-terminal FERM domain for melanosome transport in retinal pigment epithelial cells
J Neurosci
2009
29
|
| 9678669 |
Wolfrum U et al.:
Myosin VIIa as a common component of cilia and microvilli
Cell Motil Cytoskeleton
1998
40: 261-271
|
| 10414956 |
Liu X et al.:
Myosin VIIa participates in opsin transport through the photoreceptor cilium
J Neurosci
1999
19: 6267-6274
|
| 9435277 |
Self T et al.:
Shaker-1 mutations reveal roles for myosin VIIA in both development and function of cochlear hair cells
Development
1998
125: 557-566
|
| 15572405 |
Gibbs D et al.:
Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes
J Cell Sci
2004
117: 6473-6483
|
| 31009951 |
King A et al.:
Dynll1 is essential for development and promotes endochondral bone formation by regulating intraflagellar dynein function in primary cilia
Hum Mol Genet
2019
28: 2573-2588
|
| 12743369 |
Gibbs D et al.:
Abnormal phagocytosis by retinal pigmented epithelium that lacks myosin VIIa, the Usher syndrome 1B protein
Proc Natl Acad Sci U S A
2003
100: 6481-6486
|
| 21709241 |
Grati M et al.:
Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction
Proc Natl Acad Sci U S A
2011
108
|
| 17805295 |
Kazmierczak P et al.:
Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells
Nature
2007
449: 87-91
|
| 12136232 |
Ouyang XM et al.:
Mutations in the alternatively spliced exons of USH1C cause non-syndromic recessive deafness
Hum Genet
2002
111: 26-30
|
| 12107438 |
Ahmed ZM et al.:
Nonsyndromic recessive deafness DFNB18 and Usher syndrome type IC are allelic mutations of USHIC
Hum Genet
2002
110: 527-531
|
| 16987892 |
Kremer H et al.:
Usher syndrome: molecular links of pathogenesis, proteins and pathways
Hum Mol Genet
2006
15: Spec No 2 R262-R270
|
| 15590703 |
Adato A et al.:
Interactions in the network of Usher syndrome type 1 proteins
Hum Mol Genet
2005
14: 347-356
|
| 16301216 |
Reiners J et al.:
Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2
Hum Mol Genet
2005
14: 3933-3943
|
| 16434480 |
van Wijk E et al. et al.:
The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1
Hum Mol Genet
2006
15: 751-765
|
| 16301217 |
Adato A et al.:
Usherin, the defective protein in Usher syndrome type IIA, is likely to be a component of interstereocilia ankle links in the inner ear sensory cells
Hum Mol Genet
2005
14: 3921-3932
|
| 15928608 |
Reiners J et al.:
Photoreceptor expression of the Usher syndrome type 1 protein protocadherin 15 (USH1F) and its interaction with the scaffold protein harmonin (USH1C)
Mol Vis
2005
11: 347-355
|
| 12407180 |
Siemens J et al.:
The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions
Proc Natl Acad Sci U S A
2002
99
|
| 12485990 |
Boeda B et al. et al.:
Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle
EMBO J
2002
21: 6689-6699
|
| 15590698 |
Delprat B et al.:
Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly
Hum Mol Genet
2005
14: 401-410
|
| 16481439 |
Senften M et al.:
Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells
J Neurosci
2006
26: 2060-2071
|
| 10973247 |
Verpy E et al.:
A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies Usher syndrome type 1C
Nat Genet
2000
26: 51-55
|
| 21487335 |
Saihan Z et al.:
Mutations in the USH1C gene associated with sector retinitis pigmentosa and hearing loss
Retina
2011
31: 1708-1716
|
| 28031293 |
Zou J et al.:
The roles of USH1 proteins and PDZ domain-containing USH proteins in USH2 complex integrity in cochlear hair cells
Hum Mol Genet
2017
26: 624-636
|
| 25406310 |
Chen Q et al.:
Whirlin and PDZ domain-containing 7 (PDZD7) proteins are both required to form the quaternary protein complex associated with Usher syndrome type 2
J Biol Chem
2014
289
|
| 28137943 |
author information missing
Characterization of the ternary Usher syndrome SANS/ush2a/whirlin protein complex
Hum Mol Genet
2017
26: 1157-1172
|
| 22279524 |
Puffenberger EG et al. et al.:
Genetic mapping and exome sequencing identify variants associated with five novel diseases
PLoS One
2012
7
|
| 22930593 |
Vester A et al. et al.:
A loss-of-function variant in the human histidyl-tRNA synthetase (HARS) gene is neurotoxic in vivo
Hum Mutat
2013
34: 191-199
|
| 19881469 |
Yan D et al.:
Mutation analysis in the long isoform of USH2A in American patients with Usher Syndrome type II
J Hum Genet
2009
54: 732-738
|
| 32333447 |
Galatolo D et al.:
Bi-allelic mutations in HARS1 severely impair histidyl-tRNA synthetase expression and enzymatic activity causing a novel multisystem ataxic syndrome
Hum Mutat
2020
41: 1232-1237
|
| 29300381 |
Khateb S et al. et al.:
A homozygous founder missense variant in arylsulfatase G abolishes its enzymatic activity causing atypical Usher syndrome in humans
Genet Med
2018
20: 1004-1012
|
| 33300174 |
Peter VG et al.:
New clinical and molecular evidence linking mutations in ARSG to Usher syndrome type IV
Hum Mutat
2021
42: 261-271
|
| 32455177 |
Abad-Morales V et al.:
Identification of a novel homozygous ARSG mutation as the second cause of Usher syndrome type 4
Am J Ophthalmol Case Rep
2020
19
|
| 12145752 |
Fields RR et al.:
Usher syndrome type III: revised genomic structure of the USH3 gene and identification of novel mutations
Am J Hum Genet
2002
71: 607-617
|
| 19680541 |
Geller SF et al. et al.:
CLRN1 is nonessential in the mouse retina but is required for cochlear hair cell development
PLoS Genet
2009
5
|
| 19423712 |
Tian G et al. et al.:
Clarin-1, encoded by the Usher Syndrome III causative gene, forms a membranous microdomain: possible role of clarin-1 in organizing the actin cytoskeleton
J Biol Chem
2009
284
|
| 10729113 |
Weston MD et al. et al.:
Genomic structure and identification of novel mutations in usherin, the gene responsible for Usher syndrome type IIa
Am J Hum Genet
2000
66: 1199-1210
|
| 14740321 |
Weston MD et al.:
Mutations in the VLGR1 gene implicate G-protein signaling in the pathogenesis of Usher syndrome type II
Am J Hum Genet
2004
74: 357-366
|
| 17171570 |
Ebermann I et al.:
A novel gene for Usher syndrome type 2: mutations in the long isoform of whirlin are associated with retinitis pigmentosa and sensorineural hearing loss
Hum Genet
2007
121: 203-211
|
| 11138009 |
Bolz H et al.:
Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D
Nat Genet
2001
27: 108-112
|
| 11398101 |
Ahmed ZM et al.:
Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1F
Am J Hum Genet
2001
69: 25-34
|
| 12588794 |
Weil D et al. et al.:
Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin
Hum Mol Genet
2003
12: 463-471
|
| 23023331 |
Riazuddin S et al. et al.:
Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48
Nat Genet
2012
44: 1265-1271
|
| 34089643 |
Liang X et al.:
CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells
|
| 29255404 |
Wang Y et al.:
Loss of CIB2 Causes Profound Hearing Loss and Abolishes Mechanoelectrical Transduction in Mice
Front Mol Neurosci
2017
10: 401
|
| 28663585 |
Giese APJ et al. et al.:
CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells
Nat Commun
2017
8: 43
|
| 15654330 |
Belyantseva IA et al.:
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia
Nat Cell Biol
2005
7: 148-156
|
| 15590699 |
Kikkawa Y et al.:
Mutant analysis reveals whirlin as a dynamic organizer in the growing hair cell stereocilium
Hum Mol Genet
2005
14: 391-400
|
| 25550511 |
Beurg M et al.:
Subunit determination of the conductance of hair-cell mechanotransducer channels
Proc Natl Acad Sci U S A
2015
112: 1589-1594
|
| 18283100 |
Frese MA et al.:
Arylsulfatase G, a novel lysosomal sulfatase
J Biol Chem
2008
283
|
| 22689975 |
Kowalewski B et al. et al.:
Arylsulfatase G inactivation causes loss of heparan sulfate 3-O-sulfatase activity and mucopolysaccharidosis in mice
Proc Natl Acad Sci U S A
2012
109
|
| 33851099 |
Kusuluri DK et al.:
Adhesion G protein-coupled receptor VLGR1/ADGRV1 regulates cell spreading and migration by mechanosensing at focal adhesions
iScience
2021
24
|
| 17567809 |
Michalski N et al.:
Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning
J Neurosci
2007
27: 6478-6488
|
| 17360538 |
Liu X et al.:
Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells
Proc Natl Acad Sci U S A
2007
104: 4413-4418
|
| 14676276 |
Bhattacharya G et al.:
A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure
J Cell Sci
2004
117: 233-242
|
| 16114888 |
Bhattacharya G et al.:
Evidence for functional importance of usherin/fibronectin interactions in retinal basement membranes
Biochemistry
2005
44
|
| 18826961 |
van Wijk E et al. et al.:
Usher syndrome and Leber congenital amaurosis are molecularly linked via a novel isoform of the centrosomal ninein-like protein
Hum Mol Genet
2009
18: 51-64
|
| 33288907 |
Schwaller F et al. et al.:
USH2A is a Meissners corpuscle protein necessary for normal vibration sensing in mice and humans
Nat Neurosci
2021
24: 74-81
|
| 26401052 |
Zou J et al.:
Individual USH2 proteins make distinct contributions to the ankle link complex during development of the mouse cochlear stereociliary bundle
Hum Mol Genet
2015
24: 6944-6957
|
| 34201633 |
Fuster-Garcia C et al.:
Usher Syndrome: Genetics of a Human Ciliopathy
|
| 20502675 |
Yang J et al.:
Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss
PLoS Genet
2010
6
|
| 23055499 |
Grati M et al.:
Localization of PDZD7 to the stereocilia ankle-link associates this scaffolding protein with the Usher syndrome protein network
J Neurosci
2012
32
|
| 24334608 |
Zou J et al.:
Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice
Hum Mol Genet
2014
23: 2374-2390
|
| 11788194 |
Bhattacharya G et al.:
Localization and expression of usherin: a novel basement membrane protein defective in people with Ushers syndrome type IIa
Hear Res
2002
163: 1-11
|
| 32313182 |
Perrino PA et al.:
Multi-level evidence of an allelic hierarchy of USH2A variants in hearing, auditory processing and speech/language outcomes
Commun Biol
2020
3: 180
|
| 12402266 |
Nakayama J et al.:
A nonsense mutation of the MASS1 gene in a family with febrile and afebrile seizures
Ann Neurol
2002
52: 654-657
|
| 20440071 |
Ebermann I et al. et al.:
PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome
J Clin Invest
2010
120: 1812-1823
|
| 18463160 |
Jacobson SG et al. et al.:
Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism
Hum Mol Genet
2008
17: 2405-2415
|
| 30831381 |
Mathur PD et al.:
Usher syndrome and non-syndromic deafness: Functions of different whirlin isoforms in the cochlea, vestibular organs, and retina
Hear Res
2019
375: 14-24
|
| 30447021 |
Saifetiarova J et al.:
Ablation of cytoskeletal scaffolding proteins, Band 4.1B and Whirlin, leads to cerebellar purkinje axon pathology and motor dysfunction
J Neurosci Res
2019
97: 313-331
|
| 20067783 |
Zeng H et al.:
PCP effector gene Inturned is an important regulator of cilia formation and embryonic development in mammals
Dev Biol
2010
339: 418-428
|
| 29084757 |
Michel V et al. et al.:
CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival
EMBO Mol Med
2017
9: 1711-1731
|
| 27117407 |
Ebrahim S et al.:
Alternative Splice Forms Influence Functions of Whirlin in Mechanosensory Hair Cell Stereocilia
Cell Rep
2016
15: 935-943
|
| 26516054 |
Ciardo MG et al.:
Whirlin increases TRPV1 channel expression and cellular stability
Biochim Biophys Acta
2016
1863: 115-127
|
| 25698744 |
de Nooij JC et al.:
The PDZ-domain protein Whirlin facilitates mechanosensory signaling in mammalian proprioceptors
J Neurosci
2015
35: 3073-3084
|
| 22048959 |
Wang L et al.:
Whirlin interacts with espin and modulates its actin-regulatory function: an insight into the mechanism of Usher syndrome type II
Hum Mol Genet
2012
21: 692-710
|
| 29572253 |
Ahmed ZM et al.:
Inframe deletion of human ESPN is associated with deafness, vestibulopathy and vision impairment
J Med Genet
2018
55: 479-488
|
| 17584769 |
Gosens I et al. et al.:
MPP1 links the Usher protein network and the Crumbs protein complex in the retina
Hum Mol Genet
2007
16: 1993-2003
|
| 16829577 |
Mburu P et al.:
Whirlin complexes with p55 at the stereocilia tip during hair cell development
Proc Natl Acad Sci U S A
2006
103
|
| 12641734 |
author information missing
article information missing
|
| 27588451 |
author information missing
article information missing
|
| 32372680 |
author information missing
article information missing
|
| 24239741 |
author information missing
article information missing
|
| 19447093 |
author information missing
article information missing
|
| 31625146 |
author information missing
article information missing
|
| 22787034 |
author information missing
article information missing
|
| 22363448 |
author information missing
article information missing
|
| 20058854 |
author information missing
article information missing
|
| 25452429 |
author information missing
article information missing
|
| 18971469 |
author information missing
article information missing
|
| 15057245 |
author information missing
article information missing
|
| 19487694 |
author information missing
article information missing
|
| 27349180 |
author information missing
article information missing
|
| 33509951 |
author information missing
article information missing
|
| 31637240 |
author information missing
article information missing
|
| 34162842 |
author information missing
article information missing
|
| 26785147 |
author information missing
article information missing
|
| 23035094 |
author information missing
article information missing
|
| 22152675 |
author information missing
article information missing
|
| 30892938 |
author information missing
article information missing
|
| 33933680 |
author information missing
article information missing
|
| 21224392 |
author information missing
article information missing
|
| 26297806 |
author information missing
article information missing
|
| 11179005 |
author information missing
article information missing
|
| 16783569 |
author information missing
article information missing
|
| 19592253 |
author information missing
article information missing
|
| 22587682 |
author information missing
article information missing
|
| 30445565 |
author information missing
article information missing
|
| 21552264 |
author information missing
article information missing
|
| 24178751 |
author information missing
article information missing
|
| 27158779 |
author information missing
article information missing
|
| 22883145 |
author information missing
article information missing
|
| 26595381 |
author information missing
article information missing
|
| 24421332 |
author information missing
article information missing
|
| 26166481 |
author information missing
article information missing
|
| 25118024 |
author information missing
article information missing
|
| 26518474 |
author information missing
article information missing
|
| 31887266 |
author information missing
article information missing
|
| 25361962 |
author information missing
article information missing
|
| 23810536 |
author information missing
article information missing
|
| 17920017 |
author information missing
article information missing
|
| 20956381 |
author information missing
article information missing
|
| 11303027 |
author information missing
article information missing
|
| 16431929 |
author information missing
article information missing
|
| 34361034 |
author information missing
article information missing
|
| 34077761 |
author information missing
article information missing
|
| 11706030 |
author information missing
article information missing
|
| 27257214 |
author information missing
article information missing
|
| 27486780 |
author information missing
article information missing
|
| 11231901 |
author information missing
article information missing
|
| 22387996 |
author information missing
article information missing
|
| 12142464 |
author information missing
article information missing
|
| 10577904 |
author information missing
article information missing
|
| 18950741 |
author information missing
article information missing
|
| 11788826 |
author information missing
article information missing
|
| 21496787 |
author information missing
article information missing
|
| 23022101 |
author information missing
article information missing
|
| 31545650 |
author information missing
article information missing
|
| 18250199 |
author information missing
article information missing
|
| 17360648 |
author information missing
article information missing
|
| 26476603 |
author information missing
article information missing
|
| 33243178 |
author information missing
article information missing
|
| 28176794 |
author information missing
article information missing
|
| 25232951 |
author information missing
article information missing
|
| 19052621 |
author information missing
article information missing
|
| 32638265 |
author information missing
article information missing
|
| 31107948 |
author information missing
article information missing
|
| 28041644 |
author information missing
article information missing
|
| 29727693 |
author information missing
article information missing
|
| 19200523 |
author information missing
article information missing
|
| 23798057 |
author information missing
article information missing
|
| 33852348 |
author information missing
article information missing
|
| 32203505 |
author information missing
article information missing
|
| 30185526 |
author information missing
article information missing
|
| 32709945 |
author information missing
article information missing
|
| 30383886 |
author information missing
article information missing
|
| 31319499 |
author information missing
article information missing
|
| 22384920 |
author information missing
article information missing
|
| 31798623 |
author information missing
article information missing
|
| 19944405 |
author information missing
article information missing
|
| 27261005 |
author information missing
article information missing
|
| 19944400 |
author information missing
article information missing
|
| 29228333 |
author information missing
article information missing
|
| 27543293 |
author information missing
article information missing
|
| 23122589 |
author information missing
article information missing
|
| 31978331 |
author information missing
article information missing
|
| 31959991 |
author information missing
article information missing
|
| 20956560 |
author information missing
article information missing
|
| 32414360 |
author information missing
article information missing
|
| 10806483 |
author information missing
article information missing
|
| 19305393 |
author information missing
article information missing
|
| 31630787 |
author information missing
article information missing
|
| 25048963 |
author information missing
article information missing
|
| 32802948 |
author information missing
article information missing
|
| 30877126 |
author information missing
article information missing
|
| 29358401 |
author information missing
article information missing
|
| 30665704 |
author information missing
article information missing
|
| 24706950 |
author information missing
article information missing
|
| 30471717 |
author information missing
article information missing
|
| 30471718 |
author information missing
article information missing
|
| 21131974 |
author information missing
article information missing
|
| 28182636 |
author information missing
article information missing
|
| 29601588 |
author information missing
article information missing
|
| 22581229 |
author information missing
article information missing
|
| 34028558 |
author information missing
article information missing
|
| 25572396 |
author information missing
article information missing
|
| 23040496 |
author information missing
article information missing
|
| 23891469 |
author information missing
article information missing
|
| 23527195 |
author information missing
article information missing
|
| 27353389 |
author information missing
article information missing
|
| 23993197 |
author information missing
article information missing
|
| 24518672 |
author information missing
article information missing
|
| 30896965 |
author information missing
article information missing
|
| 24094744 |
author information missing
article information missing
|
| 23991085 |
author information missing
article information missing
|
| 24055112 |
author information missing
article information missing
|
| 27486783 |
author information missing
article information missing
|
| 31342671 |
author information missing
article information missing
|
| 19919626 |
author information missing
article information missing
|
| 30388400 |
author information missing
article information missing
|
| 26073779 |
author information missing
article information missing
|
| 26387594 |
author information missing
article information missing
|
| 23891471 |
author information missing
article information missing
|
| 29727692 |
author information missing
article information missing
|
| 24747639 |
author information missing
article information missing
|
| 23872636 |
author information missing
article information missing
|
| 23849778 |
author information missing
article information missing
|
| 24203976 |
author information missing
article information missing
|
| 23354437 |
author information missing
article information missing
|
| 26820108 |
author information missing
article information missing
|
| 25564561 |
author information missing
article information missing
|
| 20887964 |
author information missing
article information missing
|
| 28698599 |
author information missing
article information missing
|
| 29263200 |
author information missing
article information missing
|
| 30148830 |
author information missing
article information missing
|
| 19423554 |
author information missing
article information missing
|
| 19684019 |
author information missing
article information missing
|
| 21659505 |
author information missing
article information missing
|
| 18396146 |
author information missing
article information missing
|
| 25927852 |
author information missing
article information missing
|
| 24360805 |
author information missing
article information missing
|
| 30916986 |
author information missing
article information missing
|
| 28886341 |
author information missing
article information missing
|
| 29130579 |
author information missing
article information missing
|
| 9054938 |
author information missing
article information missing
|
| 12794692 |
author information missing
article information missing
|
| 22428873 |
author information missing
article information missing
|
| 15627218 |
author information missing
article information missing
|
| 9632163 |
author information missing
article information missing
|
| 20375059 |
author information missing
article information missing
|
| 17503333 |
author information missing
article information missing
|
| 22365972 |
author information missing
article information missing
|
| 26182404 |
author information missing
article information missing
|
| 26136363 |
author information missing
article information missing
|
| 23063620 |
author information missing
article information missing
|
| 32966817 |
author information missing
article information missing
|
| 17971504 |
author information missing
article information missing
|
| 9618177 |
author information missing
article information missing
|
| 22695961 |
author information missing
article information missing
|
| 29559409 |
author information missing
article information missing
|
| 33748110 |
author information missing
article information missing
|
| 27633000 |
author information missing
article information missing
|
| 30319355 |
author information missing
article information missing
|
| 33109612 |
author information missing
article information missing
|
| 32009068 |
author information missing
article information missing
|
| 9326941 |
author information missing
article information missing
|
| 21654732 |
author information missing
article information missing
|
| 21493626 |
author information missing
article information missing
|
| 26167768 |
author information missing
article information missing
|
| 24981858 |
author information missing
article information missing
|
| 10958647 |
author information missing
article information missing
|
| 10958648 |
author information missing
article information missing
|
| 16339905 |
author information missing
article information missing
|
| 21224891 |
author information missing
article information missing
|
| 21685204 |
author information missing
article information missing
|
| 9390563 |
author information missing
article information missing
|
| 9427255 |
author information missing
article information missing
|
| 9390562 |
author information missing
article information missing
|
| 9390516 |
author information missing
article information missing
|
| 15028672 |
author information missing
article information missing
|
| 32533067 |
author information missing
article information missing
|
| 15689355 |
author information missing
article information missing
|
| 18854042 |
author information missing
article information missing
|
| 11580893 |
author information missing
article information missing
|
| 11007889 |
author information missing
article information missing
|
| 12215455 |
author information missing
article information missing
|
| 15932940 |
author information missing
article information missing
|
| 15190009 |
author information missing
article information missing
|
| 11389483 |
author information missing
article information missing
|
| 10508521 |
author information missing
article information missing
|
| 15623792 |
author information missing
article information missing
|
| 33570491 |
author information missing
article information missing
|
| 34259627 |
author information missing
article information missing
|
| 21670265 |
author information missing
article information missing
|
| 32747192 |
author information missing
article information missing
|
| 31467083 |
author information missing
article information missing
|
| 21273506 |
author information missing
article information missing
|
| 28729419 |
author information missing
article information missing
|
| 22433857 |
author information missing
article information missing
|
| 23435566 |
author information missing
article information missing
|
| 25018876 |
author information missing
article information missing
|
| 30152084 |
author information missing
article information missing
|
| 28240221 |
author information missing
article information missing
|
| 17110339 |
author information missing
article information missing
|
| 21525244 |
author information missing
article information missing
|
| 30120216 |
author information missing
article information missing
|
| 15728249 |
author information missing
article information missing
|
| 28777934 |
author information missing
article information missing
|
| 32258032 |
author information missing
article information missing
|
| 27066478 |
author information missing
article information missing
|
| 33668384 |
author information missing
article information missing
|
| 32533184 |
author information missing
article information missing
|
| 33709122 |
author information missing
article information missing
|
| 30166529 |
author information missing
article information missing
|
| 10549638 |
author information missing
article information missing
|
| 11481257 |
author information missing
article information missing
|
| 10607826 |
author information missing
article information missing
|
| 19218615 |
author information missing
article information missing
|
| 16303976 |
author information missing
article information missing
|
| 17525220 |
author information missing
article information missing
|
| 24664738 |
author information missing
article information missing
|
| 33213002 |
author information missing
article information missing
|
| 26911694 |
author information missing
article information missing
|
| 24664737 |
author information missing
article information missing
|
| 21867699 |
author information missing
article information missing
|
| 20238006 |
author information missing
article information missing
|
| 18035352 |
author information missing
article information missing
|
| 23255580 |
author information missing
article information missing
|
| 30009826 |
author information missing
article information missing
|
| 35096838 |
author information missing
article information missing
|
| 35477418 |
author information missing
article information missing
|
| 30561082 |
author information missing
article information missing
|
| 30228185 |
author information missing
article information missing
|
| 26402555 |
author information missing
article information missing
|
| 25600267 |
author information missing
article information missing
|
| 25558901 |
author information missing
article information missing
|
| 8485575 |
author information missing
article information missing
|
| 8485576 |
author information missing
article information missing
|
| 8251014 |
author information missing
article information missing
|
| 8020945 |
author information missing
article information missing
|
| 8644804 |
author information missing
article information missing
|
| 25805137 |
author information missing
article information missing
|
| 30819798 |
author information missing
article information missing
|
| 35861669 |
author information missing
article information missing
|
| 35344225 |
author information missing
article information missing
|
| 30307502 |
author information missing
article information missing
|
| 29961824 |
author information missing
article information missing
|
| 35741845 |
author information missing
article information missing
|
| 30221600 |
author information missing
article information missing
|
| 21506742 |
author information missing
article information missing
|
| 28624967 |
author information missing
article information missing
|
| 35740972 |
author information missing
article information missing
|
| 29272450 |
author information missing
article information missing
|
| 21427764 |
author information missing
article information missing
|
| 33015954 |
author information missing
article information missing
|
| 33075816 |
author information missing
article information missing
|
| 30578315 |
author information missing
article information missing
|
| 28625565 |
author information missing
article information missing
|
| 28428259 |
author information missing
article information missing
|
| 24825419 |
author information missing
article information missing
|
| 33241915 |
author information missing
article information missing
|
| 23055941 |
author information missing
article information missing
|
| 26926036 |
author information missing
article information missing
|
| 28082521 |
author information missing
article information missing
|
| 20531442 |
author information missing
article information missing
|
| 12503095 |
author information missing
article information missing
|
| 30573683 |
author information missing
article information missing
|
| 34535504 |
author information missing
article information missing
|
| 25848030 |
author information missing
article information missing
|
| 16399502 |
author information missing
article information missing
|
| 34385262 |
author information missing
article information missing
|
| 39695235 |
author information missing
article information missing
|
| 34759842 |
author information missing
article information missing
|
| 35397207 |
author information missing
article information missing
|
| 23150283 |
author information missing
article information missing
|
| 36846582 |
author information missing
article information missing
|
| 35997788 |
author information missing
article information missing
|
| 15461667 |
author information missing
article information missing
|
| 25134614 |
author information missing
article information missing
|
| 11877439 |
Zhang YJ et al.:
Identification of dynein heavy chain 7 as an inner arm component of human cilia that is synthesized but not assembled in a case of primary ciliary dyskinesia
J. Biol. Chem.
2002
277
|
| 26937387 |
Ravn K et al.:
Neonatal mitochondrial hepatoencephalopathy caused by novel GFM1 mutations
Mol Genet Metab Rep
2015
3: 5-10
|
| 21549344 |
Gotz A et al.:
Exome sequencing identifies mitochondrial alanyl-tRNA synthetase mutations in infantile mitochondrial cardiomyopathy
Am. J. Hum. Genet.
2011
88: 635-642
|
| 25058219 |
Taylor RW et al. et al.:
Use of whole-exome sequencing to determine the genetic basis of multiple mitochondrial respiratory chain complex deficiencies
JAMA
2014
312: 68-77
|
| 21549344 |
Gotz A et al. et al.:
Exome sequencing identifies mitochondrial alanyl-tRNA synthetase mutations in infantile mitochondrial cardiomyopathy
Am. J. Hum. Genet.
2011
88: 635-642
|
| 23929671 |
Baruffini E et al.:
MTO1 mutations are associated with hypertrophic cardiomyopathy and lactic acidosis and cause respiratory chain deficiency in humans and yeast
Hum. Mutat.
2013
34: 1501-1509
|
| 23849775 |
Haack TB et al.:
ELAC2 mutations cause a mitochondrial RNA processing defect associated with hypertrophic cardiomyopathy
Am. J. Hum. Genet.
2013
93: 211-223
|
| 23315540 |
Carroll CJ et al.:
Whole-exome sequencing identifies a mutation in the mitochondrial ribosome protein MRPL44 to underlie mitochondrial infantile cardiomyopathy
J. Med. Genet.
2013
50: 151-159
|
| 10446428 |
Ganesh Bhat B et al.:
Rat sn-glycerol-3-phosphate acyltransferase: molecular cloning and characterization of the cDNA and expressed protein.
Biochim. Biophys. Acta
1999
1439: 415-423
|
| 12417724 |
Hammond LE et al.:
Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition
Mol. Cell. Biol.
2002
22: 8204-8214
|
| 1721057 |
Shin DH et al.:
Transcriptional regulation of p90 with sequence homology to Escherichia coli glycerol-3-phosphate acyltransferase.
J. Biol. Chem.
1991
266
|
| 10051453 |
Muoio DM et al.:
AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target.
Biochem. J.
1999
338: 783-791
|
| 598501 |
Bates EJ et al.:
Acute effects of insulin on glycerol phosphate acyl transferase activity, ketogenesis and serum free fatty acid concentration in perfused rat liver.
FEBS Lett.
1977
84: 225-228
|
| 598502 |
et al.:
A selective decrease in mitochondrial glycerol phosphate acyltransferase activity in livers from streptozotocin-diabetic rats
FEBS Lett.
1977
84: 229-232
|
| 518562 |
Bates EJ et al.:
A study of the glycerol phosphate acyltransferase and dihydroxyacetone phosphate acyltransferase activities in rat liver mitochondrial and microsomal fractions. Relative distribution in parenchymal and non-parenchymal cells, effects of N-ethylmaleimide, palmitoyl-coenzyme A concentration, starvation, adrenalectomy and anti-insulin serum treatment.
Biochem. J.
1979
182: 751-762
|
| 15280151 |
Ameen C et al.:
Effects of gender and GH secretory pattern on sterol regulatory element-binding protein-1c and its target genes in rat liver.
Am. J. Physiol. Endocrinol. Metab.
2004
287
|
| 15878874 |
Hammond LE et al.:
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs
J. Biol. Chem.
2005
280
|
| 16054099 |
Neschen S et al.:
Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice.
Cell Metab.
2005
2: 55-65
|
| 16935266 |
Xu H et al.:
Hepatic knockdown of mitochondrial GPAT1 in ob/ob mice improves metabolic profile
Biochem. Biophys. Res. Commun.
2006
349: 439-448
|
| 15778226 |
Onorato TM et al.:
Phosphorylation of rat liver mitochondrial glycerol-3-phosphate acyltransferase by casein kinase 2
J. Biol. Chem.
2005
280
|
| 12207885 |
Onorato TM et al.:
Casein kinase II stimulates rat liver mitochondrial glycerophosphate acyltransferase activity
Biochem. Biophys. Res. Commun.
2002
296: 1091-1096
|
| 15708364 |
Collison LW et al.:
Aging reduces glycerol-3-phosphate acyltransferase activity in activated rat splenic T-lymphocytes
Biochim. Biophys. Acta
2005
1-3: 164-172
|
| 12573444 |
Kannan L et al.:
Aging and acyl-CoA binding protein alter mitochondrial glycerol-3-phosphate acyltransferase activity
Biochim. Biophys. Acta
2003
1631: 12-16
|
| 10585467 |
Shimano H et al.:
Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes
J. Biol. Chem.
1999
274
|
| 11124951 |
Xu J et al.:
Polyunsaturated fatty acids suppress hepatic sterol regulatory element-binding protein-1 expression by accelerating transcript decay
J. Biol. Chem.
2001
276: 9800-9807
|
| 10535992 |
Foretz M et al.:
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
Proc. Natl. Acad. Sci. U.S.A.
1999
96
|
| 10570128 |
Shimomura I et al.:
Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes
Proc. Natl. Acad. Sci. U.S.A.
1999
96
|
| 10207099 |
Foretz M et al.:
ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose
Mol. Cell. Biol.
1999
5: 3760-3768
|
| 10949029 |
Shimomura I et al.:
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
Mol. Cell
2000
6: 77-86
|
| 9600904 |
Horton JD et al.:
Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice
Proc. Natl. Acad. Sci. U.S.A.
1998
95: 5987-5992
|
| 9421459 |
Kim JB et al.:
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1
J. Clin. Invest.
1998
101: 1-9
|
| 11679417 |
Becard D et al.:
Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice
Diabetes
2001
50: 2425-2430
|
| 11443121 |
Chakravarty K et al.:
Sterol regulatory element-binding protein-1c mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription
J. Biol. Chem.
2001
276
|
| 10485707 |
Shimomura I et al.:
Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
Nature
1999
401: 73-76
|
| 10514488 |
Shimomura I et al.:
Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus
J. Biol. Chem.
1999
274
|
| 10973319 |
Lin HZ et al.:
Metformin reverses fatty liver disease in obese, leptin-deficient mice.
Nat. Med.
2000
6: 998-1003
|
| 11602624 |
Zhou G et al.:
Role of AMP-activated protein kinase in mechanism of metformin action
J. Clin. Invest.
2001
108: 1167-1174
|
| 11602624 |
Zhou G et al.:
Role of AMP-activated protein kinase in mechanism of metformin action
J. Clin. Invest.
2001
108: 1167-1174
|
| 19363290 |
Kammoun HL et al.:
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice
J. Clin. Invest.
2009
5: 1201-1215
|
| 19363290 |
Kammoun HL et al.:
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice
J. Clin. Invest.
2009
119: 1201-1215
|
| 9054427 |
Ericsson J et al.:
Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene.
J. Biol. Chem.
1997
272: 7298-7305
|
| 9054427 |
Ericsson J et al.:
Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene
J. Biol. Chem.
1997
272: 7298-7305
|
| 18339309 |
Yazdi M et al.:
The role of mitochondrial glycerol-3-phosphate acyltransferase-1 in regulating lipid and glucose homeostasis in high-fat diet fed mice
Biochem. Biophys. Res. Commun.
2008
369: 1065-1070
|
| 15102885 |
Linden D et al.:
Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis
J. Lipid Res.
2004
45: 1279-1288
|
| 16507761 |
Linden D et al.:
Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation
FASEB J.
2006
20: 434-443
|
| 11546763 |
Igal RA et al.:
Mitochondrial glycerol phosphate acyltransferase directs the incorporation of exogenous fatty acids into triacylglycerol.
J. Biol. Chem.
2001
276
|
| 17389595 |
Nagle CA et al.:
Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance
J. Biol. Chem.
2007
282
|
| 15598672 |
Lewin TM et al.:
Mitochondrial glycerol-3-phosphate acyltransferase-1 directs the metabolic fate of exogenous fatty acids in hepatocytes
Am. J. Physiol. Endocrinol. Metab.
2005
288: E835-E844
|
| 17258706 |
Hammond LE et al.:
Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice
Exp. Mol. Pathol.
2007
82: 210-219
|
| 7961630 |
Vancura A et al.:
Purification and characterization of glycerophosphate acyltransferase from rat liver mitochondria
J. Biol. Chem.
1994
269
|
| 17493869 |
Pellon-Maison M et al.:
Mitochondrial glycerol-3-P acyltransferase 1 is most active in outer mitochondrial membrane but not in mitochondrial associated vesicles (MAV)
Biochim. Biophys. Acta
2007
1771: 830-838
|
| 11716470 |
Lewin TM et al.:
Regulation of mitochondrial sn-glycerol-3-phosphate acyltransferase activity: response to feeding status is unique in various rat tissues and is discordant with protein expression
Arch. Biochem. Biophys.
2001
396: 119-127
|
| 14724270 |
Lewin TM et al.:
Identification of a new glycerol-3-phosphate acyltransferase isoenzyme, mtGPAT2, in mitochondria
J. Biol. Chem.
2004
279
|
| 17689486 |
Wang S et al.:
Cloning and functional characterization of a novel mitochondrial N-ethylmaleimide-sensitive glycerol-3-phosphate acyltransferase (GPAT2)
Arch. Biochem. Biophys.
2007
465: 347-358
|
| 17013544 |
Harada N et al.:
Molecular cloning of a murine glycerol-3-phosphate acyltransferase-like protein 1 (xGPAT1)
Mol. Cell. Biochem.
2007
297: 41-51
|
| 17170135 |
Cao J et al.:
Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis.
Proc. Natl. Acad. Sci. U.S.A.
2006
103
|
| 16436371 |
Vergnes L et al.:
Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity
J. Lipid Res.
2006
47: 745-754
|
| 12938015 |
Li D et al.:
Cloning and identification of the human LPAAT-zeta gene, a novel member of the lysophosphatidic acid acyltransferase family.
J. Hum. Genet.
2003
48: 438-442
|
| 18238778 |
Chen YQ et al.:
AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase
J. Biol. Chem.
2008
283
|
| 15247243 |
Kerner J et al.:
Phosphorylation of rat liver mitochondrial carnitine palmitoyltransferase-I: effect on the kinetic properties of the enzyme
J. Biol. Chem.
2004
279
|
| 6615474 |
Mills SE et al.:
Interaction of malonyl-CoA and related compounds with mitochondria from different rat tissues. Relationship between ligand binding and inhibition of carnitine palmitoyltransferase I.
Biochem. J.
1983
214: 83-91
|
| 17147517 |
Sanders MJ et al.:
Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade
Biochem. J.
2007
403: 139-148
|
| 16308421 |
Shaw RJ et al.:
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.
Science
2005
310: 1642-1646
|
| 15855317 |
Foretz M et al.:
Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver.
Diabetes
2005
54: 1331-1339
|
| 12847291 |
Hong SP et al.:
Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases.
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 8839-8843
|
| 15793229 |
Pold R et al.:
Long-term AICAR administration and exercise prevents diabetes in ZDF rats.
Diabetes
2005
54: 928-934
|
| 15561958 |
Cleasby ME et al.:
Metformin prevents the development of acute lipid-induced insulin resistance in the rat through altered hepatic signaling mechanisms.
Diabetes
2004
53: 3258-3266
|
| 11994296 |
Fryer LG et al.:
The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.
J. Biol. Chem.
2002
277
|
| 14733947 |
Saha AK et al.:
Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo.
Biochem. Biophys. Res. Commun.
2004
314: 580-585
|
| 12446579 |
Ye JM et al.:
Prior thiazolidinedione treatment preserves insulin sensitivity in normal rats during acute fatty acid elevation: role of the liver.
Endocrinology
2002
143: 4527-4535
|
| 12368907 |
Yamauchi T et al.:
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase.
Nat. Med.
2002
8: 1288-1295
|
| 12065578 |
Park H et al.:
Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise.
J. Biol. Chem.
2002
277
|
| 18390901 |
Gauthier MS et al.:
AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance.
J. Biol. Chem.
2008
283
|
| 18390901 |
Gauthier MS et al.:
AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance
J. Biol. Chem.
2008
283
|
| 18845612 |
Dzamko N et al.:
AMPK-independent pathways regulate skeletal muscle fatty acid oxidation
J. Physiol. (Lond.)
2008
586: 5819-5831
|
| 9693118 |
Salt I et al.:
AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform.
Biochem. J.
1998
334: 177-187
|
| 12805220 |
Baas AF et al.:
Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD.
EMBO J.
2003
22: 3062-3072
|
| 16449762 |
Beigneux AP et al.:
Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium
J. Lipid Res.
2006
47: 734-744
|
| 14517248 |
Boudeau J et al.:
MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm.
EMBO J.
2003
22: 5102-5114
|
| 8549768 |
Davies SP et al.:
5-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC.
FEBS Lett.
1995
377: 421-425
|
| 14511394 |
Hawley SA et al.:
Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
J. Biol.
2003
2: 28
|
| 16054095 |
Hawley SA et al.:
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase.
Cell Metab.
2005
2: 9-19
|
| 15980064 |
Hurley RL et al.:
The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases.
J. Biol. Chem.
2005
280
|
| 18522808 |
Lewin TM et al.:
Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition
Biochim. Biophys. Acta
2008
1781: 352-358
|
| 16054096 |
Woods A et al.:
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.
Cell Metab.
2005
2: 21-33
|
| 11287605 |
Yoshikawa T et al.:
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter
Mol. Cell. Biol.
2001
9: 2991-3000
|
| 15956049 |
Assifi MM et al.:
AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats
Am. J. Physiol. Endocrinol. Metab.
2005
289: E794-E800
|
| 14976316 |
Banerjee RR et al. et al.:
Regulation of fasted blood glucose by resistin
Science
2004
303: 1195-1198
|
| 19665995 |
Kim T et al.:
Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells.
Biochem. Biophys. Res. Commun.
2009
388: 377-382
|
| 18420492 |
Cederroth CR et al.:
Dietary phytoestrogens activate AMP-activated protein kinase with improvement in lipid and glucose metabolism
Diabetes
2008
57: 1176-1185
|
| 19237574 |
Chen Y et al. et al.:
Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimers amyloid peptides via up-regulating BACE1 transcription
Proc Natl Acad Sci U S A
2009
106: 3907-3912
|
| 18971390 |
Collison LW et al.:
Glycerol-3-phosphate acyltransferase-1 regulates murine T-lymphocyte proliferation and cytokine production.
Am. J. Physiol.
2008
295
|
| 15569818 |
Chen HC et al.:
Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice.
Arterioscler. Thromb. Vasc. Biol.
2005
25: 482-486
|
| 18167308 |
Bronnikov GE et al.:
Acute effects of insulin on the activity of mitochondrial GPAT1 in primary adipocytes.
Biochem. Biophys. Res. Commun.
2008
367: 201-207
|
| 10940327 |
Coleman RA et al.:
Physiological and nutritional regulation of enzymes of triacylglycerol synthesis
Annu. Rev. Nutr.
2000
20: 77-103
|
| 11597827 |
Adeli K et al.:
Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance.
Trends Cardiovasc. Med.
2001
11: 170-176
|
| 18487474 |
Trenell MI et al.:
Increased daily walking improves lipid oxidation without changes in mitochondrial function in type 2 diabetes.
Diabetes Care
2008
31: 1644-1649
|
| 16614395 |
Dentin R et al.:
Hepatic gene regulation by glucose and polyunsaturated fatty acids: a role for ChREBP.
J. Nutr.
2006
136: 1145-1149
|
| 18023282 |
Reue K et al.:
The lipin protein family: dual roles in lipid biosynthesis and gene expression
FEBS Lett.
2008
1: 90-96
|
| 16950137 |
Finck BN et al.:
Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway
Cell Metab
2006
4: 199-210
|
| 19770177 |
Sugden MC et al.:
PPAR control: its SIRTainly as easy as PGC
J Endocrinol
2010
204: 93-104
|
| 18840364 |
Banks AS et al.:
SirT1 gain of function increases energy efficiency and prevents diabetes in mice.
Cell Metab.
2008
8: 333-341
|
| 12107756 |
Hara K et al.:
A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes
Diabetologia
2002
45: 740-743
|
| 19254570 |
Nagai Y et al.:
The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance.
Cell Metab.
2009
9: 252-264
|
| 18046409 |
Milne JC et al.:
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.
Nature
2007
450: 712-716
|
| 18599449 |
Pfluger PT et al.:
Sirt1 protects against high-fat diet-induced metabolic damage
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 9793-9798
|
| 19549853 |
Erion DM et al.:
SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats.
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 18849969 |
Liu Y et al.:
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange.
Nature
2008
456: 269-273
|
| 19356714 |
Purushotham A et al.:
Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation
Cell Metab.
2009
9: 327-338
|
| 19041393 |
Frojdo S et al.:
Alterations of insulin signaling in type 2 diabetes: a review of the current evidence from humans
Biochim. Biophys. Acta
2009
2: 83-92
|
| 17268085 |
Na M et al.:
Protein tyrosine phosphatase 1B inhibitory activity of amentoflavone and its cellular effect on tyrosine phosphorylation of insulin receptors.
Biol. Pharm. Bull.
2007
30: 379-381
|
| 18281274 |
Zabolotny JM et al.:
Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo.
J. Biol. Chem.
2008
283
|
| 16461936 |
Lam NT et al.:
Leptin resistance following over-expression of protein tyrosine phosphatase 1B in liver.
J. Mol. Endocrinol.
2006
36: 163-174
|
| 16845389 |
Bence KK et al.:
Neuronal PTP1B regulates body weight, adiposity and leptin action
Nat. Med.
2006
12: 917-924
|
| 15189365 |
Santaniemi M et al.:
Tyrosine phosphatase 1B and leptin receptor genes and their interaction in type 2 diabetes.
J. Intern. Med.
2004
256: 48-55
|
| 15715684 |
Gouni-Berthold I et al.:
The Pro387Leu variant of protein tyrosine phosphatase-1B is not associated with diabetes mellitus type 2 in a German population.
J. Intern. Med.
2005
257: 272-280
|
| 10660596 |
Goldstein BJ et al.:
Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein
J. Biol. Chem.
2000
275: 4283-4289
|
| 15031294 |
Zabolotny JM et al.:
Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action
J. Biol. Chem.
2004
279
|
| 18053812 |
de Luca C et al.:
Inflammation and insulin resistance
FEBS Lett.
2008
582: 97-105
|
| 10542212 |
Schottelius AJ et al.:
Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding
J. Biol. Chem.
1999
45
|
| 12228220 |
Rui L et al.:
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.
J. Biol. Chem.
2002
277
|
| 11001060 |
Baumann CA et al.:
CAP defines a second signalling pathway required for insulin-stimulated glucose transport.
Nature
2000
407: 202-207
|
| 7738205 |
Hotamisligil GS et al.:
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.
J. Clin. Invest.
1995
95: 2409-2415
|
| 10591334 |
Visser M et al.:
Elevated C-reactive protein levels in overweight and obese adults.
JAMA
1999
282: 2131-2135
|
| 8662983 |
Peraldi P et al.:
Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase
J Biol Chem
1996
271
|
| 9335502 |
Uysal KT et al.:
Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function.
Nature
1997
389: 610-614
|
| 8995390 |
Stephens JM et al.:
Tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction
J. Biol. Chem.
1997
272: 971-976
|
| 16818881 |
Tuncman G et al.:
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance
Proc. Natl. Acad. Sci. U.S.A.
2006
103
|
| 9817203 |
Yin MJ et al.:
The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta
Nature
1998
396: 77-80
|
| 15685173 |
Cai D et al.:
Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
Nat Med
2005
11: 183-190
|
| 15805118 |
Sugita H et al.:
Inducible nitric-oxide synthase and NO donor induce insulin receptor substrate-1 degradation in skeletal muscle cells
J. Biol. Chem.
2005
280
|
| 20532036 |
Becerril S et al.:
Deletion of inducible nitric-oxide synthase in leptin-deficient mice improves brown adipose tissue function
PLoS ONE
2010
5
|
| 15632167 |
Yasukawa T et al.:
S-nitrosylation-dependent inactivation of Akt/protein kinase B in insulin resistance
J. Biol. Chem.
2005
280: 7511-7518
|
| 11590438 |
Perreault M et al.:
Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle
Nat. Med.
2001
7: 1138-1143
|
| 15047622 |
Kim HJ et al.:
Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo
Diabetes
2004
53: 1060-1067
|
| 14679177 |
Xu H et al.:
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
J. Clin. Invest.
2003
112: 1821-1830
|
| 15685170 |
Arkan MC et al.:
IKK-beta links inflammation to obesity-induced insulin resistance
Nat. Med.
2005
11: 191-198
|
| 16341265 |
Weisberg SP et al.:
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
J. Clin. Invest.
2006
116: 115-124
|
| 20056828 |
Tateya S et al.:
An increase in the circulating concentration of monocyte chemoattractant protein-1 elicits systemic insulin resistance irrespective of adipose tissue inflammation in mice
Endocrinology
2010
3: 971-979
|
| 17192460 |
Lumeng CN et al.:
Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
Diabetes
2007
56: 16-23
|
| 17351624 |
Lesniewski LA et al.:
Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance
Nat. Med.
2007
13: 455-462
|
| 19164473 |
Riant E et al.:
Estrogens protect against high-fat diet-induced insulin resistance and glucose intolerance in mice
Endocrinology
2009
150: 2109-2117
|
| 19581423 |
Mamane Y et al.:
The C3a anaphylatoxin receptor is a key mediator of insulin resistance and functions by modulating adipose tissue macrophage infiltration and activation
Diabetes
2009
58: 2006-2017
|
| 18522830 |
Kang K et al.:
Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity
Cell Metab.
2008
6: 485-495
|
| 17959861 |
Fleischman A et al.:
Salsalate improves glycemia and inflammatory parameters in obese young adults
Diabetes Care
2008
31: 289-294
|
| 17525798 |
Hevener AL et al.:
Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
J. Clin. Invest.
2007
117: 1658-1669
|
| 17053832 |
Shi H et al.:
TLR4 links innate immunity and fatty acid-induced insulin resistance
J. Clin. Invest.
2006
11: 3015-3025
|
| 15486293 |
Ozcan U et al.:
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
Science
2004
306: 457-461
|
| 16931765 |
Ozcan U et al.:
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
Science
2006
5790: 1137-1140
|
| 20558665 |
Ouchi N et al.:
Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity.
Science
2010
329: 454-457
|
| 18562625 |
Lee YS et al.:
Dysregulation of adipose glutathione peroxidase 3 in obesity contributes to local and systemic oxidative stress
Mol. Endocrinol.
2008
22: 2176-2189
|
| 20383694 |
Jagannathan M et al.:
Toll-like receptors regulate B cell cytokine production in patients with diabetes
Diabetologia
2010
53: 1461-1471
|
| 17429083 |
Larsen CM et al.:
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
N. Engl. J. Med.
2007
356: 1517-1526
|
| 12829646 |
Kern PA et al.:
Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression
Diabetes
2003
52: 1779-1785
|
| 18239070 |
Sauter NS et al.:
The antiinflammatory cytokine interleukin-1 receptor antagonist protects from high-fat diet-induced hyperglycemia
Endocrinology
2008
149: 2208-2218
|
| 16732281 |
Netea MG et al.:
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
Nat. Med.
2006
12: 650-656
|
| 17038556 |
Jager J et al.:
Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression
Endocrinology
2007
148: 241-251
|
| 16418171 |
Weigert C et al.:
Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells
J. Biol. Chem.
2006
281: 7060-7067
|
| 18437347 |
Franckhauser S et al.:
Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice
Diabetologia
2008
51: 1306-1316
|
| 20107108 |
Kiefer FW et al.:
Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance
Diabetes
2010
59: 935-946
|
| 17698029 |
Miller RS et al.:
Repression of GLUT4 expression by the endoplasmic reticulum stress response in 3T3-L1 adipocytes
Biochem. Biophys. Res. Commun.
2007
362: 188-192
|
| 17878382 |
Wu D et al.:
Aging up-regulates expression of inflammatory mediators in mouse adipose tissue
J Immunol
2007
179: 4829-4839
|
| 17456850 |
Cani PD et al.:
Metabolic endotoxemia initiates obesity and insulin resistance
Diabetes
2007
56: 1761-1772
|
| 17991637 |
Erridge C et al.:
A high-fat meal induces low-grade endotoxemia: evidence of a novel mechanism of postprandial inflammation
Am. J. Clin. Nutr.
2007
86: 1286-1292
|
| 17993646 |
Kim JH et al.:
Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway
J. Biol. Chem.
2008
283: 708-715
|
| 18083784 |
Friedman JE et al.:
Increased skeletal muscle tumor necrosis factor-alpha and impaired insulin signaling persist in obese women with gestational diabetes mellitus 1 year postpartum
Diabetes
2008
57: 606-613
|
| 18263705 |
Maedler K et al.:
Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases
FASEB J.
2008
22: 1905-1913
|
| 12235117 |
Maedler K et al.:
Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets
J. Clin. Invest.
2002
110: 851-860
|
| 17911533 |
Zu L et al.:
Salicylate blocks lipolytic actions of tumor necrosis factor-alpha in primary rat adipocytes
Mol. Pharmacol.
2008
73: 215-223
|
| 15472206 |
Zeender E et al.:
Pioglitazone and sodium salicylate protect human beta-cells against apoptosis and impaired function induced by glucose and interleukin-1beta
J. Clin. Endocrinol. Metab.
2004
89: 5059-5066
|
| 17050683 |
Solinas G et al.:
Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates
Proc. Natl. Acad. Sci. U.S.A.
2006
103
|
| 16783472 |
Todoric J et al.:
Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids
Diabetologia
2006
49: 2109-2119
|
| 16567512 |
Neschen S et al.:
Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-gamma-dependent mechanism in mice
Diabetes
2006
55: 924-928
|
| 17086191 |
Baur JA et al.:
Resveratrol improves health and survival of mice on a high-calorie diet
Nature
2006
444: 337-342
|
| 18403477 |
Weisberg SP et al.:
Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity
Endocrinology
2008
149: 3549-3558
|
| 19211925 |
Gonzalez-Periz A et al.:
Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectins
FASEB J.
2009
23: 1946-1957
|
| 16210322 |
Talukdar I et al.:
Arachidonic acid inhibits the insulin induction of glucose-6-phosphate dehydrogenase via p38 MAP kinase
J. Biol. Chem.
2005
280
|
| 19646964 |
Kohan AB et al.:
A role for AMPK in the inhibition of glucose-6-phosphate dehydrogenase by polyunsaturated fatty acids
Biochem. Biophys. Res. Commun.
2009
388: 117-121
|
| 19787041 |
Sears DD et al.:
12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice
PLoS ONE
2009
4: E7250
|
| 19521344 |
Chakrabarti SK et al.:
12/15-lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes
Obesity (Silver Spring)
2009
17: 1657-1663
|
| 17204958 |
Aldamiz-Echevarria L et al.:
Arachidonic acid content in adipose tissue is associated with insulin resistance in healthy children
J. Pediatr. Gastroenterol. Nutr.
2007
44: 77-83
|
| 19712485 |
Warensjo E et al.:
Associations between estimated fatty acid desaturase activities in serum lipids and adipose tissue in humans: links to obesity and insulin resistance
Lipids Health Dis
2009
8: 37
|
| 18682512 |
Aguilar-Salinas CA et al.:
High adiponectin concentrations are associated with the metabolically healthy obese phenotype
J. Clin. Endocrinol. Metab.
2008
93: 4075-4079
|
| 17717599 |
Kim JY et al.:
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
J. Clin. Invest.
2007
117: 2621-2637
|
| 19088251 |
Banga A et al.:
Adiponectin translation is increased by the PPARgamma agonists pioglitazone and omega-3 fatty acids
Am. J. Physiol. Endocrinol. Metab.
2009
296: E480-E489
|
| 17569885 |
Itoh M et al.:
Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects
Arterioscler. Thromb. Vasc. Biol.
2007
27: 1918-1925
|
| 19023279 |
Rosenson RS et al.:
Effect of fenofibrate on adiponectin and inflammatory biomarkers in metabolic syndrome patients
Obesity (Silver Spring)
2009
17: 504-509
|
| 16636195 |
Hattori Y et al.:
Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells
Hypertension
2006
6: 1183-1188
|
| 20885384 |
Wang Q et al.:
Effect of the cannabinoid receptor-1 antagonist rimonabant on inflammation in mice with diet-induced obesity
Obesity (Silver Spring)
2011
19: 505-513
|
| 17610002 |
Ramakers JD et al.:
Arachidonic acid but not eicosapentaenoic acid (EPA) and oleic acid activates NF-kappaB and elevates ICAM-1 expression in Caco-2 cells
Lipids
2007
42: 687-698
|
| 18854155 |
Zhang X et al.:
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity
Cell
2008
135: 61-73
|
| 15627650 |
Denys A et al.:
n-3 PUFAs modulate T-cell activation via protein kinase C-alpha and -epsilon and the NF-kappaB signaling pathway
J. Lipid Res.
2005
46: 752-758
|
| 18377686 |
Romier B et al.:
Modulation of signalling nuclear factor-kappaB activation pathway by polyphenols in human intestinal Caco-2 cells
Br. J. Nutr.
2008
100: 542-551
|
| 15698426 |
Li H et al.:
EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: evidence for a PPAR-gamma-dependent mechanism
Kidney Int.
2005
67: 867-874
|
| 18716169 |
Bose M et al.:
The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice
J. Nutr.
2008
138: 1677-1683
|
| 20816778 |
Sergent T et al.:
Anti-inflammatory effects of dietary phenolic compounds in an in vitro model of inflamed human intestinal epithelium
Chem Biol Interact
2010
188: 659-667
|
| 20511545 |
Hong Byun E et al.:
TLR4 signaling inhibitory pathway induced by green tea polyphenol epigallocatechin-3-gallate through 67-kDa laminin receptor
J. Immunol.
2010
185: 33-45
|
| 18753616 |
Birsoy K et al.:
Cellular program controlling the recovery of adipose tissue mass: An in vivo imaging approach
Proc. Natl. Acad. Sci. U.S.A.
2008
105
|
| 15070774 |
Gao Q et al.:
Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation
Proc. Natl. Acad. Sci. U.S.A.
2004
101: 4661-4666
|
| 18382766 |
Hill JW et al.:
Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice
J. Clin. Invest.
2008
118: 1796-1805
|
| 12594516 |
Bates SH et al.:
STAT3 signalling is required for leptin regulation of energy balance but not reproduction
Nature
2003
421: 856-859
|
| 19759305 |
Ernst MB et al.:
Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity
J. Neurosci.
2009
29
|
| 16794735 |
Plum L et al.:
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity
J. Clin. Invest.
2006
116: 1886-1901
|
| 18054313 |
Plum L et al. et al.:
Enhanced leptin-stimulated Pi3k activation in the CNS promotes white adipose tissue transdifferentiation
Cell Metab.
2007
6: 431-445
|
| 10862798 |
El-Haschimi K et al.:
Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity
J. Clin. Invest.
2000
105: 1827-1832
|
| 18451994 |
Koch L et al.:
Central insulin action regulates peripheral glucose and fat metabolism in mice
J Clin Invest
2008
118: 2132-2147
|
| 17550779 |
Konner AC et al.:
Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production
Cell Metab.
2007
5: 438-449
|
| 20697689 |
Matthews VB et al.:
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance
Diabetologia
2010
53: 2431-2441
|
| 20816090 |
Wunderlich FT et al.:
Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action
Cell Metab.
2010
12: 237-249
|
| 12447443 |
Hirosumi J et al.:
A central role for JNK in obesity and insulin resistance
Nature
2002
420: 333-336
|
| 20231445 |
Belgardt BF et al.:
Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 6028-6033
|
| 12351658 |
Gao Z et al.:
Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex
J. Biol. Chem.
2002
50
|
| 18267070 |
Chibalin AV et al.:
Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance
Cell
2008
132: 375-386
|
| 18267070 |
Chibalin AV et al.:
Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance
Cell
2008
132: 375-386
|
| 15536073 |
Lin Y et al. et al.:
The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species
J Biol Chem
2005
280: 4617-4626
|
| 17519423 |
Tsukumo DM et al.:
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance
Diabetes
2007
56: 1986-1998
|
| 16798732 |
Senn JJ et al.:
Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes
J. Biol. Chem.
2006
281
|
| 17916553 |
Nguyen MT et al.:
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
J. Biol. Chem.
2007
48
|
| 18624726 |
Schaeffler A et al.:
Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity
Immunology
2009
126: 233-245
|
| 18957619 |
Hommelberg PP et al.:
Fatty acid-induced NF-kappaB activation and insulin resistance in skeletal muscle are chain length dependent.
Am. J. Physiol. Endocrinol. Metab.
2009
296: E114-E120
|
| 18421279 |
Davis JE et al.:
Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat
Obesity (Silver Spring)
2008
16: 1248-1255
|
| 18787058 |
Caricilli AM et al.:
Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet.
J. Endocrinol.
2008
199: 399-406
|
| 19883619 |
Saberi M et al.:
Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice
Cell Metab.
2009
10: 419-429
|
| 18633101 |
Reyna SM et al.:
Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects.
Diabetes
2008
57: 2595-2602
|
| 1733902 |
Fishbain DA et al.:
Acute surgical abdominal disease in schizophrenics.
Isr. J. Med. Sci.
1992
28: 61
|
| 21054880 |
Bunn RC et al.:
Palmitate and insulin synergistically induce IL-6 expression in human monocytes.
Cardiovasc Diabetol
2010
9: 73
|
| 19240062 |
Cani PD et al.:
Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability.
Gut
2009
58: 1091-1103
|
| 16002529 |
De Souza CT et al.:
Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus.
Endocrinology
2005
146: 4192-4199
|
| 19116375 |
Posey KA et al.:
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet.
Am. J. Physiol. Endocrinol. Metab.
2009
296
|
| 19808018 |
Kleinridders A et al.:
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity.
Cell Metab.
2009
10: 249-259
|
| 20824098 |
Hosoi T et al.:
Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice
|
| 19117545 |
Ozcan L et al.:
Endoplasmic reticulum stress plays a central role in development of leptin resistance.
Cell Metab.
2009
9: 35-51
|
| 19144836 |
Milanski M et al.:
Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity
J. Neurosci.
2009
29: 359-370
|
| 19144836 |
Milanski M et al.:
Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity.
J. Neurosci.
2009
29: 359-370
|
| 19087258 |
Lehrke M et al.:
Serum concentrations of cortisol, interleukin 6, leptin and adiponectin predict stress induced insulin resistance in acute inflammatory reactions.
Crit Care
2008
12: R157
|
| 20808781 |
Ropelle ER et al.:
IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition
|
| 19955656 |
Wueest S et al.:
Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice.
J. Clin. Invest.
2010
120: 191-202
|
| 19707530 |
Ahonen T et al.:
Gender differences relating to metabolic syndrome and proinflammation in Finnish subjects with elevated blood pressure.
Mediators Inflamm.
2009
2009
|
| 17392546 |
Thorand B et al.:
Sex differences in the prediction of type 2 diabetes by inflammatory markers: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002.
Diabetes Care
2007
30: 854-860
|
| 21365005 |
Murdolo G et al.:
Inflammatory adipokines, high molecular weight adiponectin, and insulin resistance: a population-based survey in prepubertal schoolchildren.
PLoS ONE
2011
6
|
| 19502419 |
Kelly M et al.:
Activation of AMP-activated protein kinase by interleukin-6 in rat skeletal muscle: association with changes in cAMP, energy state, and endogenous fuel mobilization
Diabetes
2009
58: 1953-1960
|
| 18549505 |
Gonzales AM et al.:
Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes.
Nutr Metab (Lond)
2008
5: 17
|
| 11334418 |
Ducluzeau PH et al.:
Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes.
Diabetes
2001
50: 1134-1142
|
| 11679436 |
Pratipanawatr W et al.:
Skeletal muscle insulin resistance in normoglycemic subjects with a strong family history of type 2 diabetes is associated with decreased insulin-stimulated insulin receptor substrate-1 tyrosine phosphorylation.
Diabetes
2001
50: 2572-2578
|
| 10331418 |
Jacob S et al.:
Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.
Diabetes
1999
48: 1113-1119
|
| 9916137 |
Dresner A et al.:
Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
J. Clin. Invest.
1999
103: 253-259
|
| 18177724 |
Koves TR et al.:
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance.
Cell Metab.
2008
7: 45-56
|
| 21116821 |
Kohlstedt K et al.:
Adipocyte-derived lipids increase angiotensin-converting enzyme (ACE) expression and modulate macrophage phenotype
Basic Res. Cardiol.
2011
106: 205-215
|
| 20660625 |
Bindom SM et al.:
Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice.
Diabetes
2010
59: 2540-2548
|
| 21330640 |
van der Zijl NJ et al.:
Valsartan improves {beta}-cell function and insulin sensitivity in subjects with impaired glucose metabolism: a randomized controlled trial
Diabetes Care
2011
34: 845-851
|
| 15037562 |
Shiuchi T et al.:
Angiotensin II type-1 receptor blocker valsartan enhances insulin sensitivity in skeletal muscles of diabetic mice
Hypertension
2004
43: 1003-1010
|
| 9498644 |
Carlsson PO et al.:
Angiotensin II and the endocrine pancreas: effects on islet blood flow and insulin secretion in rats
Diabetologia
1998
41: 127-133
|
| 12031955 |
Janke J et al.:
Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors.
Diabetes
2002
51: 1699-1707
|
| 16452552 |
Lupi R et al.:
The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets.
Eur. J. Endocrinol.
2006
154: 355-361
|
| 9539311 |
Miyata T et al.:
Bradykinin potentiates insulin-stimulated glucose uptake and enhances insulin signal through the bradykinin B2 receptor in dog skeletal muscle and rat L6 myoblasts.
Eur. J. Endocrinol.
1998
138: 344-352
|
| 852980 |
Gilat T et al.:
Bile composition in a Tel Aviv population.
Isr. J. Med. Sci.
1977
13: 320-323
|
| 20349036 |
Deshmukh AS et al.:
Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)alpha1-specific activity and glucose transport in human skeletal muscle.
Diabetologia
2010
53: 1142-1150
|
| 19901849 |
Munoz MC et al.:
Long-term treatment with an angiotensin II receptor blocker decreases adipocyte size and improves insulin signaling in obese Zucker rats.
J. Hypertens.
2009
27: 2409-2420
|
| 20390403 |
Rong X et al.:
Angiotensin II type 1 receptor-independent beneficial effects of telmisartan on dietary-induced obesity, insulin resistance and fatty liver in mice
|
| 19713141 |
Saitoh Y et al.:
Telmisartan attenuates fatty-acid-induced oxidative stress and NAD(P)H oxidase activity in pancreatic beta-cells.
Diabetes Metab.
2009
35: 392-397
|
| 20100990 |
Cole BK et al.:
Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice.
Hypertension
2010
55: 715-721
|
| 16650382 |
Shao J et al.:
Beneficial effects of candesartan, an angiotensin II type 1 receptor blocker, on beta-cell function and morphology in db/db mice.
Biochem. Biophys. Res. Commun.
2006
344: 1224-1233
|
| 20808802 |
Zhang F et al.:
Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration.
PLoS ONE
2010
5
|
| 19166939 |
Al-Maghrebi M et al.:
Endogenous angiotensin-(1-7) reduces cardiac ischemia-induced dysfunction in diabetic hypertensive rats
Pharmacol. Res.
2009
59: 263-268
|
| 15494608 |
Blendea MC et al.:
Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression
Am. J. Physiol. Endocrinol. Metab.
2005
288: E353-E359
|
| 15705782 |
Juan CC et al.:
Angiotensin II enhances insulin sensitivity in vitro and in vivo.
Endocrinology
2005
146: 2246-2254
|
| 11145613 |
Saint-Marc P et al.:
Angiotensin II as a trophic factor of white adipose tissue: stimulation of adipose cell formation.
Endocrinology
2001
142: 487-492
|
| 12011658 |
Gorzelniak K et al.:
Hormonal regulation of the human adipose-tissue renin-angiotensin system: relationship to obesity and hypertension
J. Hypertens.
2002
20: 965-973
|
| 17371337 |
Yilmaz MI et al.:
Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndrome.
Nephrology (Carlton)
2007
12: 147-153
|
| 17533199 |
Wei Y et al.:
NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat.
Hypertension
2007
50: 384-391
|
| 18073321 |
Wei Y et al.:
Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-kappaB activation via NADPH oxidase.
Am. J. Physiol. Endocrinol. Metab.
2008
294: E345-E351
|
| 19074984 |
Mitsuishi M et al.:
Angiotensin II reduces mitochondrial content in skeletal muscle and affects glycemic control.
Diabetes
2009
58: 710-717
|
| 17827829 |
Ichikawa Y et al.:
Comparative effects of telmisartan and valsartan on insulin resistance in hypertensive patients with metabolic syndrome
Intern. Med.
2007
46: 1331-1336
|
| 18787107 |
Cheng Q et al.:
Combination of the dipeptidyl peptidase IV inhibitor LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] with the angiotensin II type 1 receptor antagonist valsartan [N-(1-oxopentyl)-N-[[2-(1H-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl]-L-valine] enhances pancreatic islet morphology and function in a mouse model of type 2 diabetes.
J. Pharmacol. Exp. Ther.
2008
327: 683-691
|
| 15922295 |
Nakayama M et al.:
Increased expression of NAD(P)H oxidase in islets of animal models of Type 2 diabetes and its improvement by an AT1 receptor antagonist.
Biochem. Biophys. Res. Commun.
2005
332: 927-933
|
| 11597291 |
Yusuf S et al.:
Ramipril and the development of diabetes
JAMA
2001
286: 1882-1885
|
| 21116607 |
Gerstein HC et al.:
Long-term effect of rosiglitazone and/or ramipril on the incidence of diabetes
Diabetologia
2011
54: 487-495
|
| 12628950 |
Vermes E et al.:
Enalapril reduces the incidence of diabetes in patients with chronic heart failure: insight from the Studies Of Left Ventricular Dysfunction (SOLVD)
Circulation
2003
107: 1291-1296
|
| 12195132 |
Lindholm LH et al.:
Risk of new-onset diabetes in the Losartan Intervention For Endpoint reduction in hypertension study
J. Hypertens.
2002
20: 1879-1886
|
| 15983242 |
Yusuf S et al.:
Effects of candesartan on the development of a new diagnosis of diabetes mellitus in patients with heart failure
Circulation
2005
112: 48-53
|
| 2440624 |
Skidgel RA et al.:
The broad substrate specificity of human angiotensin I converting enzyme.
Clin Exp Hypertens A
1987
9: 243-259
|
| 7876104 |
Rousseau A et al.:
The hemoregulatory peptide N-acetyl-Ser-Asp-Lys-Pro is a natural and specific substrate of the N-terminal active site of human angiotensin-converting enzyme.
J. Biol. Chem.
1995
270: 3656-3661
|
| 20310083 |
Castoldi G et al.:
Prevention of myocardial fibrosis by N-acetyl-seryl-aspartyl-lysyl-proline in diabetic rats.
Clin. Sci.
2010
118: 211-220
|
| 15734863 |
Shibuya K et al.:
N-acetyl-seryl-aspartyl-lysyl-proline prevents renal insufficiency and mesangial matrix expansion in diabetic db/db mice.
Diabetes
2005
54: 838-845
|
| 21507365 |
Vardeny O et al.:
Opposing effects of beta blockers and angiotensin-converting enzyme inhibitors on development of new-onset diabetes mellitus in patients with stable coronary artery disease
Am. J. Cardiol.
2011
107: 1705-1709
|
| 9165097 |
Hayakari M et al.:
Kinetic evaluation of beta-neoendorphin hydrolysis by the somatic and testicular isozymes of human angiotensin-converting enzyme.
Biochim. Biophys. Acta
1997
1339: 31-38
|
| 2554881 |
Dubreuil P et al.:
Novel activity of angiotensin-converting enzyme. Hydrolysis of cholecystokinin and gastrin analogues with release of the amidated C-terminal dipeptide.
Biochem. J.
1989
262: 125-130
|
| 17363457 |
Scholzen TE et al.:
Terminating the stress: peripheral peptidolysis of proopiomelanocortin-derived regulatory hormones by the dermal microvascular endothelial cell extracellular peptidases neprilysin and angiotensin-converting enzyme.
Endocrinology
2007
148: 2793-2805
|
| 2983326 |
Skidgel RA et al.:
Novel activity of human angiotensin I converting enzyme: release of the NH2- and COOH-terminal tripeptides from the luteinizing hormone-releasing hormone.
Proc. Natl. Acad. Sci. U.S.A.
1985
82: 1025-1029
|
| 15536109 |
Bakris GL et al.:
Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension: a randomized controlled trial
JAMA
2004
292: 2227-2236
|
| 18564334 |
Bell DS et al.:
Comparison of carvedilol and metoprolol on serum lipid concentration in diabetic hypertensive patients.
Diabetes Obes Metab
2009
11: 234-238
|
| 10634338 |
Meigs JB et al.:
Hyperinsulinemia, hyperglycemia, and impaired hemostasis: the Framingham Offspring Study
JAMA
2000
283: 221-228
|
| 18180317 |
Liu H et al.:
Glucagon-like peptide-1 attenuates tumour necrosis factor-alpha-mediated induction of plasminogen [corrected] activator inhibitor-1 expression.
J. Endocrinol.
2008
196: 57-65
|
| 10783895 |
Nishikawa T et al.:
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage.
Nature
2000
404: 787-790
|
| 10082470 |
Schmidt AM et al.:
Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis.
Circ. Res.
1999
84: 489-497
|
| 8761899 |
Jacob S et al.:
Differential effect of chronic treatment with two beta-blocking agents on insulin sensitivity: the carvedilol-metoprolol study
J. Hypertens.
1996
14: 489-494
|
| 8159103 |
Haenni A et al.:
Treatment with a beta-blocker with beta 2-agonism improves glucose and lipid metabolism in essential hypertension
Metab. Clin. Exp.
1994
43: 455-461
|
| 10738048 |
Gress TW et al.:
Hypertension and antihypertensive therapy as risk factors for type 2 diabetes mellitus. Atherosclerosis Risk in Communities Study
N. Engl. J. Med.
2000
342: 905-912
|
| 19475771 |
Agabiti-Rosei E et al.:
Arterial stiffness, hypertension, and rational use of nebivolol.
Vasc Health Risk Manag
2009
5: 353-360
|
| 18772860 |
Pasini AF et al.:
Nebivolol treatment reduces serum levels of asymmetric dimethylarginine and improves endothelial dysfunction in essential hypertensive patients.
Am. J. Hypertens.
2008
21: 1251-1257
|
| 16940222 |
Oelze M et al.:
Nebivolol inhibits superoxide formation by NADPH oxidase and endothelial dysfunction in angiotensin II-treated rats.
Hypertension
2006
48: 677-684
|
| 19273745 |
Van Linthout S et al.:
Vascular-protective effects of high-density lipoprotein include the downregulation of the angiotensin II type 1 receptor.
Hypertension
2009
53: 682-687
|
| 16116070 |
Dessy C et al.:
Endothelial beta3-adrenoreceptors mediate nitric oxide-dependent vasorelaxation of coronary microvessels in response to the third-generation beta-blocker nebivolol.
Circulation
2005
112: 1198-1205
|
| 20176997 |
Zhou X et al.:
Nebivolol improves diastolic dysfunction and myocardial remodeling through reductions in oxidative stress in the Zucker obese rat
Hypertension
2010
55: 880-888
|
| 21177830 |
Habibi J et al.:
Nebivolol attenuates redox-sensitive glomerular and tubular mediated proteinuria in obese rats.
Endocrinology
2011
152: 659-668
|
| 18539157 |
Wenzel P et al.:
AT1-receptor blockade by telmisartan upregulates GTP-cyclohydrolase I and protects eNOS in diabetic rats
Free Radic. Biol. Med.
2008
45: 619-626
|
| 16179591 |
Bendall JK et al.:
Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression
Circ. Res.
2005
97: 864-871
|
| 18483405 |
Tolle M et al.:
HDL-associated lysosphingolipids inhibit NAD(P)H oxidase-dependent monocyte chemoattractant protein-1 production
Arterioscler. Thromb. Vasc. Biol.
2008
8: 1542-1548
|
| 14966566 |
Nofer JR et al.:
HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3.
J. Clin. Invest.
2004
113: 569-581
|
| 10376603 |
Dimmeler S et al.:
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation.
Nature
1999
399: 601-605
|
| 20018878 |
Kimura T et al.:
Mechanism and role of high density lipoprotein-induced activation of AMP-activated protein kinase in endothelial cells
J. Biol. Chem.
2010
7: 4387-4397
|
| 20818929 |
Sanchez-Roman I et al.:
The beta-blocker atenolol lowers the longevity-related degree of fatty acid unsaturation, decreases protein oxidative damage, and increases extracellular signal-regulated kinase signaling in the heart of C57BL/6 mice.
Rejuvenation Res
2010
13: 683-693
|
| 20809949 |
Pasini E et al.:
Intracellular molecular effects of insulin resistance in patients with metabolic syndrome.
Cardiovasc Diabetol
2010
9: 46
|
| 16467663 |
Celik T et al.:
Comparative effects of nebivolol and metoprolol on oxidative stress, insulin resistance, plasma adiponectin and soluble P-selectin levels in hypertensive patients.
J. Hypertens.
2006
24: 591-596
|
| 16823248 |
Uzunlulu M et al.:
The effect of carvedilol on metabolic parameters in patients with metabolic syndrome.
Int Heart J
2006
47: 421-430
|
| 20409961 |
Fonarow GC et al.:
Differential effects of extended-release carvedilol and extended-release metoprolol on lipid profiles in patients with hypertension: results of the Extended-Release Carvedilol Lipid Trial.
J Am Soc Hypertens
2009
3: 210-220
|
| 17332679 |
Kozlovski VI et al.:
Nebivovol and carvedilol induce NO-dependent coronary vasodilatation that is unlikely to be mediated by extracellular ATP in the isolated guinea pig heart.
Pharmacol Rep
2006
58: 103-110
|
| 16303859 |
Song J et al.:
Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats.
Am. J. Physiol. Renal Physiol.
2006
290
|
| 18424559 |
Tiwari S et al.:
Impaired sodium excretion and increased blood pressure in mice with targeted deletion of renal epithelial insulin receptor.
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 6469-6474
|
| 15933859 |
Grassi G et al.:
Neuroadrenergic and reflex abnormalities in patients with metabolic syndrome.
Diabetologia
2005
48: 1359-1365
|
| 2040704 |
Anderson EA et al.:
Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans.
J. Clin. Invest.
1991
87: 2246-2252
|
| 9218503 |
Haynes WG et al.:
Receptor-mediated regional sympathetic nerve activation by leptin
J. Clin. Invest.
1997
100: 270-278
|
| 10523015 |
Ozata M et al.:
Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects
J. Clin. Endocrinol. Metab.
1999
84: 3686-3695
|
| 18815209 |
Morgan DA et al.:
Mechanisms mediating renal sympathetic activation to leptin in obesity
Am. J. Physiol. Regul. Integr. Comp. Physiol.
2008
295
|
| 11593103 |
Raasch W et al.:
Angiotensin converting enzyme inhibition improves cardiac neuronal uptake of noradrenaline in spontaneously hypertensive rats.
J. Hypertens.
2001
19: 1827-1833
|
| 11606482 |
Massiera F et al.:
Adipose angiotensinogen is involved in adipose tissue growth and blood pressure regulation
FASEB J.
2001
15: 2727-2729
|
| 15191907 |
Boustany CM et al.:
Activation of the systemic and adipose renin-angiotensin system in rats with diet-induced obesity and hypertension.
Am. J. Physiol. Regul. Integr. Comp. Physiol.
2004
287: R943-R949
|
| 18445663 |
Rossi GP et al.:
Body mass index predicts plasma aldosterone concentrations in overweight-obese primary hypertensive patients
J. Clin. Endocrinol. Metab.
2008
93: 2566-2571
|
| 20130077 |
Garg R et al.:
Aldosterone production and insulin resistance in healthy adults.
J. Clin. Endocrinol. Metab.
2010
95: 1986-1990
|
| 14614137 |
Ehrhart-Bornstein M et al.:
Human adipocytes secrete mineralocorticoid-releasing factors.
Proc. Natl. Acad. Sci. U.S.A.
2003
100
|
| 21464990 |
Ryu HS et al.:
The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes.
PLoS ONE
2011
6
|
| 18445755 |
Lastra G et al.:
Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat.
Am. J. Physiol. Endocrinol. Metab.
2008
295: E110-E116
|
| 8187280 |
Griendling KK et al.:
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.
Circ. Res.
1994
74: 1141-1148
|
| 12707286 |
Redon J et al.:
Antioxidant activities and oxidative stress byproducts in human hypertension
Hypertension
2003
41: 1096-1101
|
| 16720735 |
Johar S et al.:
Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase.
FASEB J.
2006
20: 1546-1548
|
| 11230373 |
Beswick RA et al.:
Long-term antioxidant administration attenuates mineralocorticoid hypertension and renal inflammatory response.
Hypertension
2001
37: 781-786
|
| 15792994 |
Potenza MA et al.:
Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance between NO and ET-1 production
Am. J. Physiol. Heart Circ. Physiol.
2005
289: H813-H822
|
| 21677282 |
Shemyakin A et al.:
Endothelin-1 reduces glucose uptake in human skeletal muscle in vivo and in vitro
Diabetes
2011
60: 2061-2067
|
| 11272154 |
Maddux BA et al.:
Protection against oxidative stress-induced insulin resistance in rat L6 muscle cells by mircomolar concentrations of alpha-lipoic acid.
Diabetes
2001
50: 404-410
|
| 12857675 |
Talior I et al.:
Increased glucose uptake promotes oxidative stress and PKC-delta activation in adipocytes of obese, insulin-resistant mice.
Am. J. Physiol. Endocrinol. Metab.
2003
285: E295-E302
|
| 14557439 |
Urakawa H et al.:
Oxidative stress is associated with adiposity and insulin resistance in men.
J. Clin. Endocrinol. Metab.
2003
88: 4673-4676
|
| 12941774 |
Bruce CR et al.:
Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: evidence that insulin resistance is associated with a disturbed antioxidant defense mechanism.
Diabetes
2003
52: 2338-2345
|
| 20811623 |
Bao W et al.:
Plasma heme oxygenase-1 concentration is elevated in individuals with type 2 diabetes mellitus.
PLoS ONE
2010
5
|
| 11533494 |
Yuan M et al.:
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta.
Science
2001
293: 1673-1677
|
| 11533494 |
Yuan M et al.:
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta
Science
2001
293: 1673-1677
|
| 21655062 |
Sun X et al.:
Effect of Aspirin on the Expression of Hepatocyte NF-kappaB and Serum TNF-alpha in Streptozotocin-Induced Type 2 Diabetic Rats.
J. Korean Med. Sci.
2011
26: 765-770
|
| 12021247 |
Hundal RS et al.:
Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes.
J. Clin. Invest.
2002
109: 1321-1326
|
| 16980380 |
Bosch J et al.:
Effect of ramipril on the incidence of diabetes
N. Engl. J. Med.
2006
355: 1551-1562
|
| 18981327 |
Eriksson JW et al.:
Hydrochlorothiazide, but not Candesartan, aggravates insulin resistance and causes visceral and hepatic fat accumulation: the mechanisms for the diabetes preventing effect of Candesartan (MEDICA) Study
Hypertension
2008
52: 1030-1037
|
| 21378214 |
Xu Q et al.:
Diabetes and risk of Parkinsons disease
Diabetes Care
2011
34: 910-915
|
| 20953616 |
Imatoh T et al.:
Coffee consumption but not green tea consumption is associated with adiponectin levels in Japanese males.
Eur J Nutr
2011
50: 279-284
|
| 20943752 |
Murase T et al.:
Coffee polyphenols suppress diet-induced body fat accumulation by downregulating SREBP-1c and related molecules in C57BL/6J mice.
Am. J. Physiol. Endocrinol. Metab.
2011
300: E122-E133
|
| 21267512 |
Wang P et al.:
Involvement of Leptin Receptor Long Isoform (LepRb)-STAT3 Signaling Pathway in Brain Fat Mass- and Obesity-Associated (FTO) Downregulation during Energy Restriction.
Mol. Med.
2011
17: 523-532
|
| 21037323 |
Stratigopoulos G et al.:
Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling.
J. Biol. Chem.
2011
286: 2155-2170
|
| 19543202 |
Rankinen T et al.:
FTO genotype is associated with exercise training-induced changes in body composition.
Obesity (Silver Spring)
2010
18: 322-326
|
| 21741858 |
Steemburgo T et al.:
The rs7204609 polymorphism in the fat mass and obesity-associated gene is positively associated with central obesity and microalbuminuria in patients with type 2 diabetes from Southern Brazil
J Ren Nutr
2012
22: 228-236
|
| 21369819 |
Takeuchi F et al.:
Association of genetic variants for susceptibility to obesity with type 2 diabetes in Japanese individuals.
Diabetologia
2011
54: 1350-1359
|
| 21175269 |
Ramya K et al.:
Genetic variations in the FTO gene are associated with type 2 diabetes and obesity in south Indians (CURES-79)
Diabetes Technol. Ther.
2011
13: 33-42
|
| 12040186 |
Cantley LC et al.:
The phosphoinositide 3-kinase pathway.
Science
2002
296: 1655-1657
|
| 18039790 |
Kagawa S et al.:
Impact of transgenic overexpression of SH2-containing inositol 5-phosphatase 2 on glucose metabolism and insulin signaling in mice.
Endocrinology
2008
149: 642-650
|
| 21414605 |
Hansen T et al.:
At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia
Biol. Psychiatry
2011
70: 59-63
|
| 21562757 |
Kiefer FW et al.:
Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice.
Diabetologia
2011
54: 2132-2142
|
| 21107520 |
Kluth O et al.:
Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure
Diabetologia
2011
54: 605-616
|
| 20444420 |
Zhang D et al.:
Resistance to high-fat diet-induced obesity and insulin resistance in mice with very long-chain acyl-CoA dehydrogenase deficiency.
Cell Metab.
2010
11: 402-411
|
| 16399503 |
Freeman H et al.:
Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion.
Cell Metab.
2006
3: 35-45
|
| 19906813 |
Wong N et al.:
The deletion variant of nicotinamide nucleotide transhydrogenase (Nnt) does not affect insulin secretion or glucose tolerance.
Endocrinology
2010
151: 96-102
|
| 19539600 |
Parker N et al.:
Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2
Biochim. Biophys. Acta
2009
1787: 1451-1457
|
| 20037589 |
Illig T et al.:
A genome-wide perspective of genetic variation in human metabolism.
Nat. Genet.
2010
42: 137-141
|
| 20584807 |
Solomon DH et al.:
Risk of diabetes among patients with rheumatoid arthritis, psoriatic arthritis and psoriasis
Ann. Rheum. Dis.
2010
69: 2114-2117
|
| 18372322 |
Altmaier E et al.:
Bioinformatics analysis of targeted metabolomics--uncovering old and new tales of diabetic mice under medication.
Endocrinology
2008
149: 3478-3489
|
| 14595539 |
Hernandez R et al.:
Rosiglitazone produces insulin sensitisation by increasing expression of the insulin receptor and its tyrosine kinase activity in brown adipocytes.
Diabetologia
2003
46: 1618-1628
|
| 9502777 |
Okuno A et al.:
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats.
J. Clin. Invest.
1998
101: 1354-1361
|
| 11473050 |
de Souza CJ et al.:
Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance.
Diabetes
2001
50: 1863-1871
|
| 1401068 |
Magnusson I et al.:
Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study.
J. Clin. Invest.
1992
90: 1323-1327
|
| 11334412 |
Iwata M et al.:
Pioglitazone ameliorates tumor necrosis factor-alpha-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator--activated receptor-gamma.
Diabetes
2001
50: 1083-1092
|
| 19389833 |
Dasu MR et al.:
Pioglitazone inhibits Toll-like receptor expression and activity in human monocytes and db/db mice.
Endocrinology
2009
150: 3457-3464
|
| 21572415 |
Small KS et al.:
Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes
Nat. Genet.
2011
43: 561-564
|
| 20581827 |
Voight BF et al.:
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
Nat. Genet.
2010
42: 579-589
|
| 20081858 |
Dupuis J et al.:
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Nat. Genet.
2010
42: 105-116
|
| 20419449 |
Boesgaard TW et al.:
Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people
Diabetologia
2010
53: 1647-1655
|
| 21747906 |
Liu C et al.:
Variants in GLIS3 and CRY2 are associated with type 2 diabetes and impaired fasting glucose in Chinese Hans
PLoS ONE
2011
6
|
| 21799836 |
Cui B et al.:
A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese
PLoS ONE
2011
6
|
| 20174558 |
Tsai FJ et al.:
A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese
PLoS Genet.
2010
6
|
| 17463249 |
Zeggini E et al.:
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
Science
2007
316: 1336-1341
|
| 17463246 |
Saxena R et al.:
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
Science
2007
316: 1331-1336
|
| 17463248 |
Scott LJ et al.:
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
Science
2007
316: 1341-1345
|
| 18443202 |
Lewis JP et al.:
Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies
Diabetes
2008
57: 2220-2225
|
| 18162508 |
Omori S et al.:
Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population
Diabetes
2008
57: 791-795
|
| 17293876 |
Sladek R et al.:
A genome-wide association study identifies novel risk loci for type 2 diabetes
Nature
2007
445: 881-885
|
| 18598350 |
Sanghera DK et al.:
Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk
BMC Med. Genet.
2008
9: 59
|
| 16415884 |
Grant SF et al.:
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
Nat. Genet.
2006
38: 320-323
|
| 21707949 |
Vazquez-Roque MI et al.:
Association of TCF7L2 allelic variations with gastric function, satiation, and GLP-1 levels
Clin Transl Sci
2011
4: 183-187
|
| 19386626 |
Shu L et al.:
Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function.
Hum. Mol. Genet.
2009
18: 2388-2399
|
| 9806549 |
Deeb SS et al.:
A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
Nat. Genet.
1998
20: 284-287
|
| 9467001 |
Meirhaeghe A et al.:
A genetic polymorphism of the peroxisome proliferator-activated receptor gamma gene influences plasma leptin levels in obese humans
Hum. Mol. Genet.
1998
7: 435-440
|
| 10973253 |
Altshuler D et al.:
The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
Nat. Genet.
2000
26: 76-80
|
| 12540637 |
Gloyn AL et al.:
Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
Diabetes
2003
52: 568-572
|
| 12851856 |
Reynisdottir I et al.:
Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2.
Am. J. Hum. Genet.
2003
73: 323-335
|
| 15111507 |
Florez JC et al.:
Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region.
Diabetes
2004
53: 1360-1368
|
| 17460697 |
Steinthorsdottir V et al.:
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
Nat. Genet.
2007
39: 770-775
|
| 18372903 |
Zeggini E et al.:
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
Nat. Genet.
2008
40: 638-645
|
| 19060907 |
Prokopenko I et al.:
Variants in MTNR1B influence fasting glucose levels
Nat. Genet.
2009
41: 77-81
|
| 21658282 |
Kim JY et al.:
Melatonin receptor 1 B polymorphisms associated with the risk of gestational diabetes mellitus
BMC Med. Genet.
2011
12: 82
|
| 19060909 |
Bouatia-Naji N et al.:
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk
Nat. Genet.
2009
41: 89-94
|
| 19060908 |
Lyssenko V et al.:
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion
Nat. Genet.
2009
41: 82-88
|
| 18711367 |
Yasuda K et al.:
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
Nat. Genet.
2008
40: 1092-1097
|
| 18711366 |
Unoki H et al.:
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
Nat. Genet.
2008
40: 1098-1102
|
| 20081857 |
Saxena R et al.:
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
Nat. Genet.
2010
2: 142-148
|
| 17327436 |
Winckler W et al.:
Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes
Diabetes
2007
56: 685-693
|
| 8945471 |
Yamagata K et al.:
Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1) }, authors { names std { { name ml Yamagata K, affil str Howard Hughes Medical Institute, The University of Chicago, Illinois 60637, USA
Nature
1996
384: 458-460
|
| 8945470 |
Yamagata K et al.:
Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
Nature
1996
384: 455-458
|
| 8433729 |
Froguel P et al.:
Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus.
N. Engl. J. Med.
1993
328: 697-702
|
| 16936201 |
Bonnycastle LL et al.:
Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns.
Diabetes
2006
55: 2534-2540
|
| 19734900 |
Rung J et al.:
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
Nat. Genet.
2009
41: 1110-1115
|
| 17603484 |
Sandhu MS et al.:
Common variants in WFS1 confer risk of type 2 diabetes.
Nat. Genet.
2007
39: 951-953
|
| 17186458 |
Weedon MN et al.:
A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses.
Am. J. Hum. Genet.
2006
79: 991-1001
|
| 18521185 |
Chen WM et al.:
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels
J. Clin. Invest.
2008
118: 2620-2628
|
| 16441550 |
Peschke E et al.:
Diabetic Goto Kakizaki rats as well as type 2 diabetic patients show a decreased diurnal serum melatonin level and an increased pancreatic melatonin-receptor status.
J. Pineal Res.
2006
40: 135-143
|
| 20858683 |
Soranzo N et al.:
Common variants at 10 genomic loci influence hemoglobin A(1)(C) levels via glycemic and nonglycemic pathways
Diabetes
2010
59: 3229-3239
|
| 19651813 |
Bonnefond A et al.:
Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits
Diabetes
2009
58: 2687-2697
|
| 20516203 |
Sauber J et al.:
Association of variants in gastric inhibitory polypeptide receptor gene with impaired glucose homeostasis in obese children and adolescents from Berlin
Eur. J. Endocrinol.
2010
163: 259-264
|
| 20185807 |
Ingelsson E et al.:
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans
Diabetes
2010
59: 1266-1275
|
| 21593353 |
Dumont J et al.:
FADS1 genetic variability interacts with dietary alpha-linolenic acid intake to affect serum non-HDL-cholesterol concentrations in European adolescents
J. Nutr.
2011
141: 1247-1253
|
| 19643913 |
Beer NL et al.:
The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver.
Hum. Mol. Genet.
2009
18: 4081-4088
|
| 18678614 |
Orho-Melander M et al.:
Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations.
Diabetes
2008
57: 3112-3121
|
| 21103350 |
Hu C et al.:
Variants from GIPR, TCF7L2, DGKB, MADD, CRY2, GLIS3, PROX1, SLC30A8 and IGF1 are associated with glucose metabolism in the Chinese
PLoS ONE
2010
5
|
| 15331542 |
Chimienti F et al.:
Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules.
Diabetes
2004
53: 2330-2337
|
| 16984975 |
Chimienti F et al.:
In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion.
J. Cell. Sci.
2006
119: 4199-4206
|
| 19243577 |
Egefjord L et al.:
Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?
BMC Endocr Disord
2009
9: 7
|
| 20508080 |
El Muayed M et al.:
Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function.
J. Endocrinol.
2010
206: 159-169
|
| 17671651 |
Lyssenko V et al.:
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes
J. Clin. Invest.
2007
117: 2155-2163
|
| 20490451 |
Andersson EA et al.:
Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight
Diabetologia
2010
53: 1908-1916
|
| 17804762 |
Pascoe L et al.:
Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function
Diabetes
2007
56: 3101-3104
|
| 18252897 |
Palmer ND et al.:
Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study
Diabetes
2008
57: 1093-1100
|
| 17786204 |
Staiger H et al.:
Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function
PLoS ONE
2007
2: E832
|
| 17827400 |
Grarup N et al.:
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies
Diabetes
2007
56: 3105-3111
|
| 16855264 |
Florez JC et al.:
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program
N. Engl. J. Med.
2006
355: 241-250
|
| 15448106 |
Sagen JV et al. et al.:
Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2: patient characteristics and initial response to sulfonylurea therapy
Diabetes
2004
53: 2713-2718
|
| 17213274 |
Florez JC et al.:
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone
J. Clin. Endocrinol. Metab.
2007
92: 1502-1509
|
| 17519421 |
Pearson ER et al.:
Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study.
Diabetes
2007
56: 2178-2182
|
| 18071026 |
Shu L et al.:
Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets.
Diabetes
2008
57: 645-653
|
| 17661009 |
Schafer SA et al.:
Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms
Diabetologia
2007
50: 2443-2450
|
| 21357677 |
Le Bacquer O et al.:
TCF7L2 splice variants have distinct effects on beta-cell turnover and function.
Hum. Mol. Genet.
2011
20: 1906-1915
|
| 15937669 |
Kim JH et al.:
Peroxisome proliferator-activated receptor gamma coactivator 1 alpha promoter polymorphisms are associated with early-onset type 2 diabetes mellitus in the Korean population.
Diabetologia
2005
48: 1323-1330
|
| 17327385 |
Stefan N et al.:
Genetic variations in PPARD and PPARGC1A determine mitochondrial function and change in aerobic physical fitness and insulin sensitivity during lifestyle intervention.
J. Clin. Endocrinol. Metab.
2007
92: 1827-1833
|
| 19900151 |
Gayathri SB et al.:
Association of the PPARGC1A gene polymorphism with diabetic nephropathy in an Asian Indian population (CURES-41)
Metab Syndr Relat Disord
2010
8: 119-126
|
| 18614852 |
Okauchi Y et al.:
PGC-1alpha Gly482Ser polymorphism is associated with the plasma adiponectin level in type 2 diabetic men
Endocr. J.
2008
55: 991-997
|
| 18270681 |
Ling C et al.:
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion
Diabetologia
2008
51: 615-622
|
| 17999673 |
Hui Y et al.:
Effect of peroxisome proliferator-activated receptors-gamma and co-activator-1alpha genetic polymorphisms on plasma adiponectin levels and susceptibility of non-alcoholic fatty liver disease in Chinese people
Liver Int.
2008
28: 385-392
|
| 21153532 |
Vangipurapu J et al.:
Association of indices of liver and adipocyte insulin resistance with 19 confirmed susceptibility loci for type 2 diabetes in 6,733 non-diabetic Finnish men
Diabetologia
2011
54: 563-571
|
| 20802253 |
Heni M et al.:
Glycemia determines the effect of type 2 diabetes risk genes on insulin secretion
Diabetes
2010
59: 3247-3252
|
| 19934000 |
Villareal DT et al.:
TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action.
Diabetes
2010
59: 479-485
|
| 20818381 |
Yamauchi T et al.:
A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B
Nat. Genet.
2010
42: 864-868
|
| 18451265 |
Bouatia-Naji N et al.:
A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels.
Science
2008
320: 1085-1088
|
| 19252135 |
Tan JT et al.:
Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore
Diabetes
2009
58: 1445-1449
|
| 19308350 |
Hu C et al.:
Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population
Diabetologia
2009
52: 1322-1325
|
| 19448982 |
Liu Y et al.:
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China
Diabetologia
2009
52: 1315-1321
|
| 20862305 |
Shu XO et al.:
Identification of new genetic risk variants for type 2 diabetes
PLoS Genet.
2010
6
|
| 21249489 |
Grarup N et al.:
The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals
Diabetologia
2011
54: 789-794
|
| 21186350 |
Zhou K et al.:
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes
Nat. Genet.
2011
43: 117-120
|
| 20935629 |
Heid IM et al.:
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Nat. Genet.
2010
42: 949-960
|
| 20935630 |
Speliotes EK et al.:
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Nat. Genet.
2010
42: 937-948
|
| 17959933 |
Li H et al.:
Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population
Diabetes
2008
57: 264-268
|
| 19401414 |
Takeuchi F et al. et al.:
Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population
Diabetes
2009
58: 1690-1699
|
| 21142918 |
Sato R et al.:
ABCC8 polymorphism (Ser1369Ala): influence on severe hypoglycemia due to sulfonylureas.
Pharmacogenomics
2010
11: 1743-1750
|
| 18599530 |
Feng Y et al.:
Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients
Diabetes Care
2008
31: 1939-1944
|
| 21968738 |
Lang V et al.:
The molecular genetics of sulfonylurea receptors in the pathogenesis and treatment of insulin secretory disorders and type 2 diabetes
Curr. Diab. Rep.
2011
11: 543-551
|
| 17259403 |
Florez JC et al.:
Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program
Diabetes
2007
56: 531-536
|
| 21845381 |
Florez JC et al.:
Does metformin work for everyone? A genome-wide association study for metformin response
Curr. Diab. Rep.
2011
11: 467-469
|
| 19833888 |
Simonis-Bik AM et al.:
Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function.
Diabetes
2010
59: 293-301
|
| 21887289 |
Wagner R et al.:
Glucose-Raising Genetic Variants in MADD and ADCY5 Impair Conversion of Proinsulin to Insulin.
PLoS ONE
2011
6
|
| 20676049 |
Ousset M et al.:
Loss of ATM positively regulates the expression of hypoxia inducible factor 1 (HIF-1) through oxidative stress: Role in the physiopathology of the disease.
Cell Cycle
2010
9: 2814-2822
|
| 18534819 |
Halaby MJ et al.:
ATM protein kinase mediates full activation of Akt and regulates glucose transporter 4 translocation by insulin in muscle cells.
Cell. Signal.
2008
20: 1555-1563
|
| 20956556 |
Armata HL et al.:
Requirement of the ATM/p53 tumor suppressor pathway for glucose homeostasis.
Mol. Cell. Biol.
2010
30: 5787-5794
|
| 18633108 |
Wu Y et al.:
Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population
Diabetes
2008
57: 2834-2842
|
| 20847106 |
Miyaki K et al.:
Association of a cyclin-dependent kinase 5 regulatory subunit-associated protein 1-like 1 (CDKAL1) polymorphism with elevated hemoglobin A(1)(c) levels and the prevalence of metabolic syndrome in Japanese men: interaction with dietary energy intake
Am. J. Epidemiol.
2010
172: 985-991
|
| 18285412 |
Stancakova A et al.:
Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance
J. Clin. Endocrinol. Metab.
2008
93: 1924-1930
|
| 18618095 |
Groenewoud MJ et al.:
Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps.
Diabetologia
2008
51: 1659-1663
|
| 21151568 |
Ohara-Imaizumi M et al.:
Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis.
PLoS ONE
2010
5
|
| 16155576 |
Wei FY et al.:
Cdk5-dependent regulation of glucose-stimulated insulin secretion.
Nat. Med.
2005
11: 1104-1108
|
| 21841312 |
Wei FY et al.:
Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice.
J. Clin. Invest.
2011
121: 3598-3608
|
| 19502414 |
Stancakova A et al.:
Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men
Diabetes
2009
58: 2129-2136
|
| 20852621 |
Zhang EE et al.:
Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis.
Nat. Med.
2010
16: 1152-1156
|
| 20364269 |
Nakayama K et al.:
A single nucleotide polymorphism in the FADS1/FADS2 gene is associated with plasma lipid profiles in two genetically similar Asian ethnic groups with distinctive differences in lifestyle
Hum. Genet.
2010
127: 685-690
|
| 21414826 |
Merino DM et al.:
Polymorphisms in FADS1 and FADS2 alter desaturase activity in young Caucasian and Asian adults
Mol. Genet. Metab.
2011
103: 171-178
|
| 17265032 |
Wang Y et al.:
Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype
Diabetologia
2007
50: 774-778
|
| 20622168 |
Bouatia-Naji N et al.:
Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels
Diabetes
2010
59: 2662-2671
|
| 22038520 |
Rees MG et al.:
Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk
Diabetologia
2012
55: 114-122
|
| 21674002 |
Perez-Martinez P et al.:
Glucokinase regulatory protein genetic variant interacts with omega-3 PUFA to influence insulin resistance and inflammation in metabolic syndrome.
PLoS ONE
2011
6
|
| 20980491 |
Djousse L et al.:
Dietary omega-3 fatty acids and fish consumption and risk of type 2 diabetes.
Am. J. Clin. Nutr.
2011
93: 143-150
|
| 12060056 |
Laaksonen DE et al.:
Serum fatty acid composition predicts development of impaired fasting glycaemia and diabetes in middle-aged men.
Diabet. Med.
2002
19: 456-464
|
| 12816776 |
Wang L et al.:
Plasma fatty acid composition and incidence of diabetes in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study
Am. J. Clin. Nutr.
2003
78: 91-98
|
| 21403394 |
Rhee EP et al.:
Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans.
J. Clin. Invest.
2011
121: 1402-1411
|
| 19234441 |
Fischer J et al.:
Inactivation of the Fto gene protects from obesity.
Nature
2009
458: 894-898
|
| 18296638 |
Emanuelli B et al.:
Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance.
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 3545-3550
|
| 21267535 |
Nielsen T et al.:
Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release
Diabetologia
2011
54: 1052-1056
|
| 17426251 |
Cleynen I et al.:
HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB
Mol. Cancer Res.
2007
5: 363-372
|
| 21841783 |
Ohtsubo K et al.:
Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport
Nat Med
2011
17: 1067-1075
|
| 20703447 |
Cotsapas C et al.:
Expression analysis of loci associated with type 2 diabetes in human tissues.
Diabetologia
2010
53: 2334-2339
|
| 16731844 |
Dahlman I et al.:
Downregulation of electron transport chain genes in visceral adipose tissue in type 2 diabetes independent of obesity and possibly involving tumor necrosis factor-alpha
Diabetes
2006
55: 1792-1799
|
| 15302918 |
Nakajima T et al.:
TIP27: a novel repressor of the nuclear orphan receptor TAK1/TR4.
Nucleic Acids Res.
2004
32: 4194-4204
|
| 18952825 |
Johansson A et al.:
Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis
Hum. Mol. Genet.
2009
18: 373-380
|
| 15254349 |
Jiang PH et al.:
Tumor protein p53-induced nuclear protein 1 (TP53INP1) in spontaneous chronic pancreatitis in the WBN/Kob rat: drug effects on its expression in the pancreas.
JOP
2004
5: 205-216
|
| 19118006 |
Cano CE et al.:
Tumor protein 53-induced nuclear protein 1 is a major mediator of p53 antioxidant function.
Cancer Res.
2009
69: 219-226
|
| 20160352 |
Fonseca SG et al.:
Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells.
J. Clin. Invest.
2010
120: 744-755
|
| 16195229 |
Fonseca SG et al.:
WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells.
J. Biol. Chem.
2005
280
|
| 21127832 |
Cheurfa N et al.:
Decreased insulin secretion and increased risk of type 2 diabetes associated with allelic variations of the WFS1 gene: the Data from Epidemiological Study on the Insulin Resistance Syndrome (DESIR) prospective study
Diabetologia
2011
54: 554-562
|
| 19141611 |
Chen T et al.:
Identification of zinc-finger BED domain-containing 3 (Zbed3) as a novel Axin-interacting protein that activates Wnt/beta-catenin signaling.
J. Biol. Chem.
2009
284: 6683-6689
|
| 22046406 |
Ohshige T et al.:
Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese
PLoS ONE
2011
6
|
| 19542200 |
Nicolson TJ et al.:
Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.
Diabetes
2009
58: 2070-2083
|
| 22043004 |
Bates HE et al.:
Gipr is essential for adrenocortical steroidogenesis; however, corticosterone deficiency does not mediate the favorable metabolic phenotype of Gipr(-/-) mice
Diabetes
2012
61: 40-48
|
| 21810601 |
Lyssenko V et al.:
Pleiotropic effects of GIP on islet function involve osteopontin.
Diabetes
2011
60: 2424-2433
|
| 20972533 |
Maida A et al.:
Metformin regulates the incretin receptor axis via a pathway dependent on peroxisome proliferator-activated receptor-alpha in mice.
Diabetologia
2011
54: 339-349
|
| 21673955 |
Dao TM et al.:
Resveratrol increases glucose induced GLP-1 secretion in mice: a mechanism which contributes to the glycemic control.
PLoS ONE
2011
6
|
| 21786021 |
Yang Y et al.:
The Kruppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.
Diabetologia
2011
54: 2595-2605
|
| 21147891 |
Cheung CY et al.:
Genetic variants associated with persistent central obesity and the metabolic syndrome in a 12-year longitudinal study
Eur. J. Endocrinol.
2011
164: 381-388
|
| 20117072 |
Da Silva D et al.:
Metformin reverses hexokinase and 6-phosphofructo-1-kinase inhibition in skeletal muscle, liver and adipose tissues from streptozotocin-induced diabetic mouse.
Arch. Biochem. Biophys.
2010
496: 53-60
|
| 21059863 |
Schneider HJ et al.:
Prediction of incident diabetes mellitus by baseline IGF1 levels.
Eur. J. Endocrinol.
2011
164: 223-229
|
| 20947509 |
Xuan S et al.:
Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells
J. Biol. Chem.
2010
285
|
| 10617608 |
El-Mir MY et al.:
Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.
J. Biol. Chem.
2000
275: 223-228
|
| 11118008 |
Hundal RS et al.:
Mechanism by which metformin reduces glucose production in type 2 diabetes.
Diabetes
2000
49: 2063-2069
|
| 21886784 |
Koyanagi M et al.:
Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1
PLoS ONE
2011
8
|
| 20444419 |
Kalender A et al.:
Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner
Cell Metab.
2010
5: 390-401
|
| 20577053 |
Foretz M et al.:
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
J. Clin. Invest.
2010
120: 2355-2369
|
| 10675357 |
Cusi K et al.:
Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle.
J. Clin. Invest.
2000
105: 311-320
|
| 11201732 |
Steppan CM et al.:
The hormone resistin links obesity to diabetes.
Nature
2001
409: 307-312
|
| 9354418 |
Dunn SE et al.:
Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice.
Cancer Res.
1997
57: 4667-4672
|
| 22249478 |
Sartori-Cintra AR et al.:
Regulation of hypoxia-inducible factor-1alpha (HIF-1alpha) expression by interleukin-1beta (IL-1 beta), insulin-like growth factors I (IGF-I) and II (IGF-II) in human osteoarthritic chondrocytes.
Clinics (Sao Paulo)
2012
67: 35-40
|
| 9326926 |
et al.:
Early-onset type-II diabetes mellitus (MODY4) linked to IPF1
Nat. Genet.
1997
17: 138-139
|
| 9398836 |
author information missing
Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY
Nat Genet
1997
17: 384-385
|
| 10545951 |
Malecki MT et al.:
Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus
Nat Genet
1999
23: 323-328
|
| 1354782 |
Velho G et al.:
Primary pancreatic beta-cell secretory defect caused by mutations in glucokinase gene in kindreds of maturity onset diabetes of the young.
Lancet
1992
340: 444-448
|
| 8878425 |
Velho G et al.:
Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects.
J. Clin. Invest.
1996
98: 1755-1761
|
| 9662401 |
Hattersley AT et al.:
Mutations in the glucokinase gene of the fetus result in reduced birth weight
Nat. Genet.
1998
3: 268-270
|
| 11717395 |
Boj SF et al.:
A transcription factor regulatory circuit in differentiated pancreatic cells
Proc. Natl. Acad. Sci. U.S.A.
2001
98
|
| 15983330 |
Stride A et al.:
Beta-cell dysfunction, insulin sensitivity, and glycosuria precede diabetes in hepatocyte nuclear factor-1alpha mutation carriers
Diabetes Care
2005
28: 1751-1756
|
| 10601964 |
Vaxillaire M et al.:
Insulin secretion and insulin sensitivity in diabetic and non-diabetic subjects with hepatic nuclear factor-1alpha (maturity-onset diabetes of the young-3) mutations.
Eur. J. Endocrinol.
1999
141: 609-618
|
| 11269503 |
Pontoglio M et al.:
HNF1alpha controls renal glucose reabsorption in mouse and man.
EMBO Rep.
2000
1: 359-365
|
| 9593777 |
Pontoglio M et al.:
Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.
J. Clin. Invest.
1998
101: 2215-2222
|
| 9548258 |
Hertz R et al.:
Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4alpha.
Nature
1998
392: 512-516
|
| 9371825 |
Stoffel M et al.:
The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism
Proc. Natl. Acad. Sci. U.S.A.
1997
94
|
| 17407387 |
Pearson ER et al.:
Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A gene.
PLoS Med.
2007
4: E118
|
| 10484768 |
Lindner TH et al.:
A novel syndrome of diabetes mellitus, renal dysfunction and genital malformation associated with a partial deletion of the pseudo-POU domain of hepatocyte nuclear factor-1beta
Hum. Mol. Genet.
1999
8: 2001-2008
|
| 15668393 |
Haumaitre C et al.:
Lack of TCF2/vHNF1 in mice leads to pancreas agenesis
Proc. Natl. Acad. Sci. U.S.A.
2005
102: 1490-1495
|
| 19855005 |
Sachdeva MM et al.:
Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 19487809 |
Oliver-Krasinski JM et al.:
The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice
J. Clin. Invest.
2009
119: 1888-1898
|
| 19656489 |
Gauthier BR et al.:
PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression
Cell Metab.
2009
10: 110-118
|
| 20374962 |
Gu C et al.:
Pancreatic beta cells require NeuroD to achieve and maintain functional maturity
Cell Metab
2010
11: 298-310
|
| 19843526 |
Fernandez-Zapico ME et al.:
MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells
J Biol Chem
2009
284
|
| 19122346 |
Kuroda E et al.:
Identification of minimal promoter and genetic variants of Kruppel-like factor 11 gene and association analysis with type 2 diabetes in Japanese.
Endocr. J.
2009
56: 275-286
|
| 17130512 |
Florez JC et al.:
The Kruppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people
Diabetes
2006
55: 3620-3624
|
| 15774581 |
Neve B et al. et al.:
Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function
Proc Natl Acad Sci U S A
2005
102: 4807-4812
|
| 20154088 |
Buttar NS et al.:
Distinct role of Kruppel-like factor 11 in the regulation of prostaglandin E2 biosynthesis
J Biol Chem
2010
285
|
| 21784842 |
Johansson BB et al.:
Diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl ester lipase gene-maturity onset diabetes of the young (CEL-MODY): a protein misfolding disease
J. Biol. Chem.
2011
286
|
| 20720448 |
Vesterhus M et al.:
Pancreatic function in carboxyl-ester lipase knockout mice.
Pancreatology
2010
10: 467-476
|
| 17426099 |
Plengvidhya N et al.:
PAX4 mutations in Thais with maturity onset diabetes of the young
J. Clin. Endocrinol. Metab.
2007
92: 2821-2826
|
| 21263211 |
Jo W et al.:
A novel PAX4 mutation in a Japanese patient with maturity-onset diabetes of the young
Tohoku J. Exp. Med.
2011
223: 113-118
|
| 21521872 |
Hu He KH et al.:
In vivo conditional Pax4 overexpression in mature islet beta-cells prevents stress-induced hyperglycemia in mice
Diabetes
2011
60: 1705-1715
|
| 10891400 |
Petersen HV et al.:
Pax4 represses pancreatic glucagon gene expression.
Mol. Cell Biol. Res. Commun.
2000
3: 249-254
|
| 18162506 |
Edghill EL et al.:
Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood
Diabetes
2008
57: 1034-1042
|
| 18192540 |
Molven A et al.:
Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes
Diabetes
2008
57: 1131-1135
|
| 20226046 |
Boesgaard TW et al.:
Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY).
BMC Med. Genet.
2010
11: 42
|
| 19667185 |
Borowiec M et al.:
Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction.
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 21170474 |
Galan M et al.:
Differential effects of HNF-1alpha mutations associated with familial young-onset diabetes on target gene regulation.
Mol. Med.
2011
17: 256-265
|
| 20943816 |
Bonzo JA et al.:
Metabolomics identifies novel Hnf1alpha-dependent physiological pathways in vivo.
Mol. Endocrinol.
2010
24: 2343-2355
|
| 21898408 |
Gragnoli C et al.:
Depression and type 2 diabetes: Cortisol pathway implication and investigational needs
J. Cell. Physiol.
2012
227: 2318-2322
|
| 22235252 |
Cizza G et al.:
Clinical subtypes of depression are associated with specific metabolic parameters and circadian endocrine profiles in women: the power study
PLoS ONE
2012
7
|
| 20080775 |
Huising MO et al.:
CRFR1 is expressed on pancreatic beta cells, promotes beta cell proliferation, and potentiates insulin secretion in a glucose-dependent manner
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 912-917
|
| 8491496 |
Jamerson KA et al.:
Reflex sympathetic activation induces acute insulin resistance in the human forearm.
Hypertension
1993
21: 618-623
|
| 9022074 |
Lambillotte C et al.:
Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets.
J. Clin. Invest.
1997
99: 414-423
|
| 19033418 |
Mezuk B et al.:
Depression and type 2 diabetes over the lifespan: a meta-analysis.
Diabetes Care
2008
31: 2383-2390
|
| 21883440 |
Faulenbach M et al.:
Effect of psychological stress on glucose control in patients with Type 2 diabetes.
Diabet. Med.
2012
29: 128-131
|
| 11724664 |
Khani S et al.:
Cortisol increases gluconeogenesis in humans: its role in the metabolic syndrome.
Clin. Sci.
2001
101: 739-747
|
| 17426095 |
Bruehl H et al.:
Hypothalamic-pituitary-adrenal axis dysregulation and memory impairments in type 2 diabetes.
J. Clin. Endocrinol. Metab.
2007
92: 2439-2445
|
| 11005876 |
Magarinos AM et al.:
Experimental diabetes in rats causes hippocampal dendritic and synaptic reorganization and increased glucocorticoid reactivity to stress.
Proc. Natl. Acad. Sci. U.S.A.
2000
97
|
| 12425944 |
Sankar R et al.:
Insulin-responsive glucose transporters-GLUT8 and GLUT4 are expressed in the developing mammalian brain.
Brain Res. Mol. Brain Res.
2002
107: 157-165
|
| 21754917 |
Grote CW et al.:
Insulin receptor substrate 2 expression and involvement in neuronal insulin resistance in diabetic neuropathy.
Exp Diabetes Res
2011
2011
|
| 19933989 |
Lin EH et al.:
Depression and advanced complications of diabetes: a prospective cohort study.
Diabetes Care
2010
33: 264-269
|
| 19331683 |
Tyrovolas S et al.:
Increased body mass and depressive symptomatology are associated with hypercholesterolemia, among elderly individuals; results from the MEDIS study.
Lipids Health Dis
2009
8: 10
|
| 20012009 |
Labad J et al.:
Symptoms of depression but not anxiety are associated with central obesity and cardiovascular disease in people with type 2 diabetes: the Edinburgh Type 2 Diabetes Study
Diabetologia
2010
53: 467-471
|
| 22210236 |
Labad J et al.:
Leptin levels and depressive symptoms in people with type 2 diabetes: the edinburgh type 2 diabetes study
Psychosom Med
2012
74: 39-45
|
| 20097784 |
Reynolds RM et al.:
Morning cortisol levels and cognitive abilities in people with type 2 diabetes: the Edinburgh type 2 diabetes study
Diabetes Care
2010
33: 714-720
|
| 19167831 |
Bruehl H et al.:
A blunted cortisol awakening response and hippocampal atrophy in type 2 diabetes mellitus.
Psychoneuroendocrinology
2009
34: 815-821
|
| 17965449 |
Cosgrove MP et al.:
Does depression increase the risk of developing type 2 diabetes?
Occup Med (Lond)
2008
58: 7-14
|
| 19455303 |
Ronnemaa E et al.:
Glucose metabolism and the risk of Alzheimers disease and dementia: a population-based 12 year follow-up study in 71-year-old men
Diabetologia
2009
52: 1504-1510
|
| 18401020 |
Ronnemaa E et al.:
Impaired insulin secretion increases the risk of Alzheimer disease
Neurology
2008
71: 1065-1071
|
| 15477536 |
Luchsinger JA et al.:
Hyperinsulinemia and risk of Alzheimer disease
Neurology
2004
63: 1187-1192
|
| 18599528 |
Driver JA et al.:
Prospective cohort study of type 2 diabetes and the risk of Parkinsons disease
Diabetes Care
2008
31: 2003-2005
|
| 17251276 |
Hu G et al.:
Type 2 diabetes and the risk of Parkinsons disease
Diabetes Care
2007
30: 842-847
|
| 18559656 |
Becker C et al.:
Diabetes in patients with idiopathic Parkinsons disease.
Diabetes Care
2008
31: 1808-1812
|
| 17761552 |
Simon KC et al.:
Hypertension, hypercholesterolemia, diabetes, and risk of Parkinson disease
Neurology
2007
69: 1688-1695
|
| 20387270 |
Tong M et al.:
Nitrosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimers disease
J. Alzheimers Dis.
2009
17: 827-844
|
| 14962073 |
Moreira PI et al.:
Effect of streptozotocin-induced diabetes on rat brain mitochondria.
J. Neuroendocrinol.
2004
16: 32-38
|
| 10713291 |
Park CR et al.:
Intracerebroventricular insulin enhances memory in a passive-avoidance task.
Physiol. Behav.
2000
68: 509-514
|
| 16890939 |
Moosavi M et al.:
The effect of intrahippocampal insulin microinjection on spatial learning and memory
Horm Behav
2006
50: 748-752
|
| 17349729 |
Babri S et al.:
Intrahippocampal insulin improves memory in a passive-avoidance task in male wistar rats
Brain Cogn
2007
64: 86-91
|
| 12153485 |
Breidert T et al.:
Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinsons disease.
J. Neurochem.
2002
82: 615-624
|
| 14690537 |
Dehmer T et al.:
Protection by pioglitazone in the MPTP model of Parkinsons disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation.
J. Neurochem.
2004
88: 494-501
|
| 18332857 |
Quinn LP et al.:
The PPARgamma agonist pioglitazone is effective in the MPTP mouse model of Parkinsons disease through inhibition of monoamine oxidase B.
Br. J. Pharmacol.
2008
154: 226-233
|
| 19500683 |
Ross AP et al.:
A high fructose diet impairs spatial memory in male rats.
Neurobiol Learn Mem
2009
92: 410-416
|
| 20176121 |
McNay EC et al.:
Hippocampal memory processes are modulated by insulin and high-fat-induced insulin resistance
Neurobiol Learn Mem
2010
93: 546-553
|
| 21109190 |
Suzuki R et al.:
Diabetes and insulin in regulation of brain cholesterol metabolism.
Cell Metab.
2010
12: 567-579
|
| 9202122 |
Montague CT et al. et al.:
Congenital leptin deficiency is associated with severe early-onset obesity in humans
Nature
1997
387: 903-908
|
| 7624776 |
Pelleymounter MA et al.:
Effects of the obese gene product on body weight regulation in ob/ob mice
Science
1995
269: 540-543
|
| 18516053 |
Buettner C et al.:
Leptin controls adipose tissue lipogenesis via central, STAT3-independent mechanisms.
Nat. Med.
2008
14: 667-675
|
| 9389752 |
Siegrist-Kaiser CA et al.:
Direct effects of leptin on brown and white adipose tissue
J. Clin. Invest.
1997
100: 2858-2864
|
| 18790715 |
Rhee SD et al.:
Leptin inhibits rosiglitazone-induced adipogenesis in murine primary adipocytes
Mol. Cell. Endocrinol.
2008
294: 61-69
|
| 17579277 |
Brown R et al.:
Adipokine gene expression in a novel hypothalamic neuronal cell line: resistin-dependent regulation of fasting-induced adipose factor and SOCS-3.
Neuroendocrinology
2007
85: 232-241
|
| 18191822 |
Clark KA et al.:
Systemic administration of leptin decreases plasma corticosterone levels: role of hypothalamic norepinephrine.
Brain Res.
2008
1195: 89-95
|
| 20212497 |
Shin AC et al.:
Chronic exposure to a high-fat diet affects stress axis function differentially in diet-induced obese and diet-resistant rats.
Int J Obes (Lond)
2010
34: 1218-1226
|
| 20368473 |
Tomiyama AJ et al.:
Low calorie dieting increases cortisol.
Psychosom Med
2010
72: 357-364
|
| 17785367 |
Stimson RH et al.:
Dietary macronutrient content alters cortisol metabolism independently of body weight changes in obese men.
J. Clin. Endocrinol. Metab.
2007
92: 4480-4484
|
| 8782827 |
Vaisse C et al.:
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
Nat. Genet.
1996
14: 95-97
|
| 16714386 |
Chan JL et al.:
Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans.
Proc. Natl. Acad. Sci. U.S.A.
2006
103: 8481-8486
|
| 15602591 |
Taheri S et al.:
Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index.
PLoS Med.
2004
1: E62
|
| 17595220 |
Muller H et al.:
Angiotensin II stimulates the reactivity of the pituitary-adrenal axis in leptin-resistant Zucker rats, thereby influencing the glucose utilization.
Am. J. Physiol. Endocrinol. Metab.
2007
293: E802-E810
|
| 11340336 |
Arvaniti K et al.:
Effects of leptin and corticosterone on the expression of corticotropin-releasing hormone, agouti-related protein, and proopiomelanocortin in the brain of ob/ob mouse.
Neuroendocrinology
2001
73: 227-236
|
| 9604864 |
Uehara Y et al.:
Hypothalamic corticotropin-releasing hormone is a mediator of the anorexigenic effect of leptin.
Diabetes
1998
47: 890-893
|
| 8787671 |
Schwartz MW et al.:
Identification of targets of leptin action in rat hypothalamus.
J. Clin. Invest.
1996
98: 1101-1106
|
| 18810709 |
Germano CM et al.:
Downregulation of melanocortin-4 receptor during refeeding and its modulation by adrenalectomy in rats
Horm. Metab. Res.
2008
40: 842-847
|
| 18195492 |
Siawrys G et al.:
Expression of leptin and long form of leptin receptor genes and proteins in pituitary of cyclic and pregnant pigs
J. Physiol. Pharmacol.
2007
58: 845-857
|
| 21777028 |
Vujovic P et al.:
Time-dependent effects of starvation on serum, pituitary and hypothalamic leptin levels in rats
Physiol Res
2011
60: S165-S170
|
| 9200662 |
Bornstein SR et al.:
Evidence for a novel peripheral action of leptin as a metabolic signal to the adrenal gland: leptin inhibits cortisol release directly
Diabetes
1997
46: 1235-1238
|
| 9751508 |
Pralong FP et al.:
Leptin inhibits directly glucocorticoid secretion by normal human and rat adrenal gland
Endocrinology
1998
139: 4264-4268
|
| 9888542 |
Kruse M et al.:
Leptin down-regulates the steroid producing system in the adrenal
Endocr. Res.
1998
24: 587-590
|
| 9851794 |
Glasow A et al.:
Expression of Ob receptor in normal human adrenals: differential regulation of adrenocortical and adrenomedullary function by leptin
J. Clin. Endocrinol. Metab.
1998
83: 4459-4466
|
| 8717038 |
Ahima RS et al.:
Role of leptin in the neuroendocrine response to fasting
Nature
1996
382: 250-252
|
| 20943959 |
Campbell JE et al.:
Adipogenic and lipolytic effects of chronic glucocorticoid exposure
Am. J. Physiol.
2011
300: C198-C209
|
| 22408618 |
Kubera B et al.:
The brains supply and demand in obesity
Front Neuroenergetics
2012
4: 4
|
| 21660101 |
Peters A et al.:
The selfish brain: stress and eating behavior
Front Neurosci
2011
5: 74
|
| 21577022 |
Peters A et al.:
Why doesnt the brain lose weight, when obese people diet
Obes Facts
2011
4: 151-157
|
| 22016099 |
Faulconbridge LF et al.:
One-Year Changes in Symptoms of Depression and Weight in Overweight/Obese Individuals With Type 2 Diabetes in the Look AHEAD Study
Obesity (Silver Spring)
2012
20: 783-793
|
| 11375373 |
Anderson RJ et al.:
The prevalence of comorbid depression in adults with diabetes: a meta-analysis
Diabetes Care
2001
24: 1069-1078
|
| 17363746 |
name consortium Look AHEAD Research Group et al.:
Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial
Diabetes Care
2007
30: 1374-1383
|
| 7714007 |
Madsen PL et al.:
Persistent resetting of the cerebral oxygen/glucose uptake ratio by brain activation: evidence obtained with the Kety-Schmidt technique
J. Cereb. Blood Flow Metab.
1995
15: 485-491
|
| 10910009 |
Fruehwald-Schultes B et al.:
Comparison of the inhibitory effect of insulin and hypoglycemia on insulin secretion in humans
Metab. Clin. Exp.
2000
7: 950-953
|
| 19965917 |
Klement J et al.:
High-calorie glucose-rich food attenuates neuroglycopenic symptoms in patients with Addisons disease
J. Clin. Endocrinol. Metab.
2010
95: 522-528
|
| 18997672 |
Rutters F et al.:
Acute stress-related changes in eating in the absence of hunger
Obesity (Silver Spring)
2009
17: 72-77
|
| 18996133 |
Rutters F et al.:
Hyperactivity of the HPA axis is related to dietary restraint in normal weight women
Physiol. Behav.
2009
96: 315-319
|
| 19828258 |
George SA et al.:
CRH-stimulated cortisol release and food intake in healthy, non-obese adults
Psychoneuroendocrinology
2010
35: 607-612
|
| 17251273 |
Chan O et al.:
ATP-sensitive K(+) channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia
Diabetes
2007
56: 1120-1126
|
| 17635959 |
Blodgett DM et al.:
Structural basis of GLUT1 inhibition by cytoplasmic ATP
J. Gen. Physiol.
2007
130: 157-168
|
| 18591392 |
Gonzalez JA et al.:
Metabolism-independent sugar sensing in central orexin neurons
Diabetes
2008
57: 2569-2576
|
| 19279289 |
Warne JP et al.:
Disengaging insulin from corticosterone: roles of each on energy intake and disposition
Am J Physiol Regul Integr Comp Physiol
2009
296
|
| 17537466 |
Serlachius A et al.:
Stress and weight change in university students in the United Kingdom
Physiol. Behav.
2007
92: 548-553
|
| 10357442 |
Oliver G et al.:
Perceived effects of stress on food choice
Physiol. Behav.
1999
66: 511-515
|
| 19584906 |
Peters A et al.:
Build-ups in the supply chain of the brain: on the neuroenergetic cause of obesity and type 2 diabetes mellitus
Front Neuroenergetics
2009
1: 2
|
| 22529374 |
Horn S et al.:
Mind bomb 1 is required for pancreatic beta-cell formation
Proc. Natl. Acad. Sci. U.S.A.
2012
109: 7356-7361
|
| 18541545 |
Flaa A et al.:
Does sympathoadrenal activity predict changes in body fat? An 18-y follow-up study
Am. J. Clin. Nutr.
2008
87: 1596-1601
|
| 21123586 |
Pankevich DE et al.:
Caloric restriction experience reprograms stress and orexigenic pathways and promotes binge eating
J. Neurosci.
2010
30
|
| 19465744 |
Block JP et al.:
Psychosocial stress and change in weight among US adults
Am. J. Epidemiol.
2009
170: 181-192
|
| 19808765 |
Kivimaki M et al.:
Common mental disorder and obesity: insight from four repeat measures over 19 years: prospective Whitehall II cohort study
BMJ
2009
339: B3765
|
| 17470564 |
Kaufman D et al.:
Early-life stress and the development of obesity and insulin resistance in juvenile bonnet macaques
Diabetes
2007
56: 1382-1386
|
| 18448080 |
Entringer S et al.:
Prenatal psychosocial stress exposure is associated with insulin resistance in young adults
Am. J. Obstet. Gynecol.
2008
199: 498
|
| 22366160 |
Martens EA et al.:
Sex differences in HPA axis activity in response to a meal
Physiol. Behav.
2012
106: 272-277
|
| 20849868 |
Martens MJ et al.:
Effects of single macronutrients on serum cortisol concentrations in normal weight men
Physiol. Behav.
2010
101: 563-567
|
| 20616886 |
Hitze B et al.:
How the selfish brain organizes its supply and demand
Front Neuroenergetics
2010
2: 7
|
| 22152222 |
Martins PJ et al.:
Type of diet modulates the metabolic response to sleep deprivation in rats
Nutr Metab (Lond)
2011
8: 86
|
| 21853062 |
Everson CA et al.:
Repeated exposure to severely limited sleep results in distinctive and persistent physiological imbalances in rats
PLoS ONE
2011
6
|
| 21799479 |
Knutson KL et al.:
No association between leptin levels and sleep duration or quality in obese adults
Obesity (Silver Spring)
2011
19: 2433-2435
|
| 21286230 |
Hayes AL et al.:
Sleep duration and circulating adipokine levels
Sleep
2011
34: 147-152
|
| 17237424 |
Moschen AR et al.:
Visfatin, an adipocytokine with proinflammatory and immunomodulating properties
J. Immunol.
2007
178: 1748-1758
|
| 22091264 |
Hajianfar H et al.:
The effect of omega-3 on the serum visfatin concentration in patients with type II diabetes
J Res Med Sci
2011
16: 490-495
|
| 21694775 |
McGee KC et al.:
Visfatin is regulated by rosiglitazone in type 2 diabetes mellitus and influenced by NFkappaB and JNK in human abdominal subcutaneous adipocytes
PLoS ONE
2011
6
|
| 22284243 |
Kadoglou NP et al.:
The association of physical activity with novel adipokines in patients with type 2 diabetes
Eur. J. Intern. Med.
2012
23: 137-142
|
| 16775236 |
Graham TE et al.:
Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects
N. Engl. J. Med.
2006
354: 2552-2563
|
| 15126529 |
Vgontzas AN et al.:
Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines
J. Clin. Endocrinol. Metab.
2004
89: 2119-2126
|
| 19850688 |
Kumari M et al.:
Self-reported sleep duration and sleep disturbance are independently associated with cortisol secretion in the Whitehall II study
J. Clin. Endocrinol. Metab.
2009
94: 4801-4809
|
| 19641160 |
Vgontzas AN et al.:
Insomnia with objective short sleep duration is associated with type 2 diabetes: A population-based study
Diabetes Care
2009
32: 1980-1985
|
| 19238807 |
Patel SR et al.:
Sleep duration and biomarkers of inflammation
Sleep
2009
32: 200-204
|
| 22518133 |
Sabanayagam C et al.:
Markers of Sleep Disordered Breathing and Diabetes Mellitus in a Multiethnic Sample of US Adults: Results from the National Health and Nutrition Examination Survey (2005-2008)
Int J Endocrinol
2012
2012
|
| 17524614 |
Frey DJ et al.:
The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults
Brain Behav. Immun.
2007
21: 1050-1057
|
| 22363403 |
Ahmed A et al.:
A switch in hepatic cortisol metabolism across the spectrum of non alcoholic fatty liver disease
PLoS ONE
2012
7
|
| 21266326 |
Stimson RH et al.:
Increased whole-body and sustained liver cortisol regeneration by 11beta-hydroxysteroid dehydrogenase type 1 in obese men with type 2 diabetes provides a target for enzyme inhibition
Diabetes
2011
60: 720-725
|
| 20932307 |
Vara Prasad SS et al.:
Dietary fatty acid composition alters 11beta-hydroxysteroid dehydrogenase type 1 gene expression in rat retroperitoneal white adipose tissue
Lipids Health Dis
2010
9: 111
|
| 21696642 |
Sakamuri VP et al.:
Vitamin A decreases pre-receptor amplification of glucocorticoids in obesity: study on the effect of vitamin A on 11beta-hydroxysteroid dehydrogenase type 1 activity in liver and visceral fat of WNIN/Ob obese rats
Nutr J
2011
10: 70
|
| 21406612 |
Man TY et al.:
Dietary manipulation reveals an unexpected inverse relationship between fat mass and adipose 11beta-hydroxysteroid dehydrogenase type 1
Am. J. Physiol. Endocrinol. Metab.
2011
300
|
| 22357964 |
Nixon M et al.:
Salicylate downregulates 11beta-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization
Diabetes
2012
61: 790-796
|
| 22357964 |
Nixon M et al.:
Salicylate downregulates 11beta-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization
Diabetes
2012
61: 790-796
|
| 18852329 |
Stimson RH et al.:
Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans
Diabetes
2009
58: 46-53
|
| 17593901 |
Alberti L et al.:
Type 2 diabetes and metabolic syndrome are associated with increased expression of 11beta-hydroxysteroid dehydrogenase 1 in obese subjects
Int J Obes (Lond)
2007
31: 1826-1831
|
| 12466357 |
Andrews RC et al.:
Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance
J. Clin. Endocrinol. Metab.
2002
87: 5587-5593
|
| 18029262 |
Bhat BG et al.:
Antisense inhibition of 11betahydroxysteroid dehydrogenase type 1 improves diabetes in a novel cortisone-induced diabetic KK mouse model
Biochem. Biophys. Res. Commun.
2008
365: 740-745
|
| 22001161 |
Blum A et al.:
Momordica charantia extract, a herbal remedy for type 2 diabetes, contains a specific 11beta-hydroxysteroid dehydrogenase type 1 inhibitor
J. Steroid Biochem. Mol. Biol.
2012
128: 51-55
|
| 22457205 |
Senanayake GV et al.:
Mechanisms underlying decreased hepatic triacylglycerol and cholesterol by dietary bitter melon extract in the rat
Lipids
2012
47: 495-503
|
| 11678826 |
Duclos M et al.:
Fat distribution in obese women is associated with subtle alterations of the hypothalamic-pituitary-adrenal axis activity and sensitivity to glucocorticoids
Clin. Endocrinol. (Oxf)
2001
55: 447-454
|
| 21272190 |
Feig PU et al.:
Effects of an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor, MK-0916, in patients with type 2 diabetes mellitus and metabolic syndrome
Diabetes Obes Metab
2011
13: 498-504
|
| 21622477 |
Gambineri A et al.:
A combination of polymorphisms in HSD11B1 associates with in vivo 11{beta}-HSD1 activity and metabolic syndrome in women with and without polycystic ovary syndrome
Eur. J. Endocrinol.
2011
165: 283-292
|
| 15156315 |
Nair S et al.:
11beta-Hydroxysteroid dehydrogenase Type 1: genetic polymorphisms are associated with Type 2 diabetes in Pima Indians independently of obesity and expression in adipocyte and muscle
Diabetologia
2004
47: 1088-1095
|
| 16503918 |
Hipolide DC et al.:
Paradoxical sleep deprivation and sleep recovery: effects on the hypothalamic-pituitary-adrenal axis activity, energy balance and body composition of rats
J. Neuroendocrinol.
2006
18: 231-238
|
| 20041117 |
Andersson T et al.:
Tissue-specific increases in 11beta-hydroxysteroid dehydrogenase type 1 in normal weight postmenopausal women
PLoS ONE
2009
4: E8475
|
| 19934376 |
Malavasi EL et al.:
Functional effects of polymorphisms in the human gene encoding 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1): a sequence variant at the translation start of 11 beta-HSD1 alters enzyme levels
Endocrinology
2010
151: 195-202
|
| 21869537 |
Moon SS et al.:
Relationship of 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase gene polymorphisms with metabolic syndrome and type 2 diabetes
Endocr. J.
2011
58: 949-959
|
| 15280030 |
Atanasov AG et al.:
Hexose-6-phosphate dehydrogenase determines the reaction direction of 11beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase
FEBS Lett.
2004
571: 129-133
|
| 20413513 |
Rosenstock J et al.:
The 11-beta-hydroxysteroid dehydrogenase type 1 inhibitor INCB13739 improves hyperglycemia in patients with type 2 diabetes inadequately controlled by metformin monotherapy
Diabetes Care
2010
33: 1516-1522
|
| 15071189 |
Sandeep TC et al.:
11Beta-hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics
Proc. Natl. Acad. Sci. U.S.A.
2004
101: 6734-6739
|
| 12519867 |
Andrews RC et al.:
Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes
J. Clin. Endocrinol. Metab.
2003
88: 285-291
|
| 11739957 |
Masuzaki H et al.:
A transgenic model of visceral obesity and the metabolic syndrome
Science
2001
294: 2166-2170
|
| 22474371 |
Cohen S et al.:
Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk
Proc. Natl. Acad. Sci. U.S.A.
2012
109: 5995-5999
|
| 21825133 |
Schmid J et al.:
Modulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11beta-hydroxysteroid dehydrogenase
Proc. Natl. Acad. Sci. U.S.A.
2011
108
|
| 14697232 |
Duplomb L et al.:
Increased expression and activity of 11beta-HSD-1 in diabetic islets and prevention with troglitazone
Biochem. Biophys. Res. Commun.
2004
313: 594-599
|
| 18479468 |
Veniant MM et al.:
Time of the day for 11beta-HSD1 inhibition plays a role in improving glucose homeostasis in DIO mice
Diabetes Obes Metab
2009
11: 109-117
|
| 21949844 |
Terao M et al.:
11beta-Hydroxysteroid dehydrogenase-1 is a novel regulator of skin homeostasis and a candidate target for promoting tissue repair
PLoS ONE
2011
6
|
| 18779947 |
Swali A et al.:
11beta-Hydroxysteroid dehydrogenase type 1 regulates insulin and glucagon secretion in pancreatic islets
Diabetologia
2008
51: 2003-2011
|
| 16322389 |
Chiodini I et al.:
Association of subclinical hypercortisolism with type 2 diabetes mellitus: a case-control study in hospitalized patients
Eur. J. Endocrinol.
2005
153: 837-844
|
| 20086312 |
Murakami H et al.:
The frequency of type 2 diabetic patients who meet the endocrinological screening criteria of subclinical Cushings disease
Endocr. J.
2010
57: 267-272
|
| 20086312 |
Murakami H et al.:
The frequency of type 2 diabetic patients who meet the endocrinological screening criteria of subclinical Cushings disease
Endocr. J.
2010
57: 267-272
|
| 19226268 |
Schoorlemmer RM et al.:
Relationships between cortisol level, mortality and chronic diseases in older persons
Clin. Endocrinol. (Oxf)
2009
71: 779-786
|
| 21212858 |
Yi SS et al.:
Effects of hypothyroidism on cell proliferation and neuroblasts in the hippocampal dentate gyrus in a rat model of type 2 diabetes
Anat Cell Biol
2010
43: 185-193
|
| 15994759 |
Johnson EO et al.:
Experimentally-induced hyperthyroidism is associated with activation of the rat hypothalamic-pituitary-adrenal axis
Eur. J. Endocrinol.
2005
153: 177-185
|
| 18278039 |
Stranahan AM et al.:
Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons
Nat. Neurosci.
2008
11: 309-317
|
| 22408122 |
Reynolds RM et al.:
Glucocorticoid treatment and impaired mood, memory and metabolism in people with diabetes: the Edinburgh Type 2 Diabetes Study
Eur. J. Endocrinol.
2012
166: 861-868
|
| 1850357 |
Kamilaris TC et al.:
Effects of short and long duration hypothyroidism and hyperthyroidism on the plasma adrenocorticotropin and corticosterone responses to ovine corticotropin-releasing hormone in rats
Endocrinology
1991
128: 2567-2576
|
| 19463794 |
Bruehl H et al.:
Modifiers of cognitive function and brain structure in middle-aged and elderly individuals with type 2 diabetes mellitus
Brain Res.
2009
1280: 186-194
|
| 9329975 |
Delaunay F et al.:
Pancreatic beta cells are important targets for the diabetogenic effects of glucocorticoids
J. Clin. Invest.
1997
100: 2094-2098
|
| 22022575 |
Gathercole LL et al.:
Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue
PLoS ONE
2011
6
|
| 22022575 |
Gathercole LL et al.:
Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue
PLoS ONE
2011
6
|
| 11802770 |
Vaz FM et al.:
Carnitine biosynthesis in mammals
Biochem. J.
2002
Pt: 3 417-429
|
| 10856709 |
Kerner J et al.:
Fatty acid import into mitochondria
Biochim. Biophys. Acta
2000
1: 1-17
|
| 11257506 |
Ramsay RR et al.:
Molecular enzymology of carnitine transfer and transport
Biochim. Biophys. Acta
2001
1546: 21-43
|
| 19553674 |
Noland RC et al.:
Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control
J. Biol. Chem.
2009
284
|
| 21770048 |
Ringseis R et al.:
Regular endurance exercise improves the diminished hepatic carnitine status in mice fed a high-fat diet
Mol Nutr Food Res
2011
55: S193-S202
|
| 22701716 |
Sampey BP et al.:
Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation
PLoS ONE
2012
7
|
| 22040461 |
Keller J et al.:
Effect of L-carnitine on the hepatic transcript profile in piglets as animal model
Nutr Metab (Lond)
2011
8: 76
|
| 11819455 |
Liang LJ et al.:
A study of the ameliorating effects of carnitine on hepatic steatosis induced by total parenteral nutrition in rats
World J. Gastroenterol.
1999
5: 312-315
|
| 20068559 |
Malaguarnera M et al.:
L-carnitine supplementation to diet: a new tool in treatment of nonalcoholic steatohepatitis--a randomized and controlled clinical trial
Am. J. Gastroenterol.
2010
105: 1338-1345
|
| 14770177 |
An J et al.:
Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance
Nat. Med.
2004
10: 268-274
|
| 19875619 |
Bain JR et al.:
Metabolomics applied to diabetes research: moving from information to knowledge
Diabetes
2009
58: 2429-2443
|
| 18945875 |
Makowski L et al.:
Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation
FASEB J.
2009
23: 586-604
|
| 18945875 |
Makowski L et al.:
Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation
FASEB J.
2009
23: 586-604
|
| 19356713 |
Newgard CB et al.:
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
Cell Metab.
2009
9: 311-326
|
| 20943795 |
Mozaffarian D et al.:
Circulating palmitoleic acid and risk of metabolic abnormalities and new-onset diabetes
Am. J. Clin. Nutr.
2010
92: 1350-1358
|
| 21173413 |
Mozaffarian D et al.:
Trans-palmitoleic acid, metabolic risk factors, and new-onset diabetes in U.S. adults: a cohort study
Ann. Intern. Med.
2010
153: 790-799
|
| 19369366 |
Adams SH et al.:
Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women
J Nutr
2009
139: 1073-1081
|
| 19502541 |
Huffman KM et al.:
Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women
Diabetes Care
2009
9: 1678-1683
|
| 20921216 |
Huffman KM et al.:
Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity
Diabetes Care
2011
1: 174-176
|
| 22523532 |
Huffman KM et al.:
Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial
PLoS ONE
2012
7
|
| 19714868 |
Bao Y et al.:
Metabonomic variations in the drug-treated type 2 diabetes mellitus patients and healthy volunteers
J. Proteome Res.
2009
8: 1623-1630
|
| 19066319 |
Zhao X et al.:
Changes of the plasma metabolome during an oral glucose tolerance test: is there more than glucose to look at
Am. J. Physiol. Endocrinol. Metab.
2009
296: E384-E393
|
| 20676218 |
Zhao X et al.:
Metabonomic fingerprints of fasting plasma and spot urine reveal human pre-diabetic metabolic traits
Metabolomics
2010
6: 362-374
|
| 20467011 |
Molfino A et al.:
Caloric restriction and L-carnitine administration improves insulin sensitivity in patients with impaired glucose metabolism
JPEN J Parenter Enteral Nutr
2010
34: 295-299
|
| 18587407 |
Biddinger SB et al.:
Hepatic insulin resistance directly promotes formation of cholesterol gallstones
Nat. Med.
2008
14: 778-782
|
| 18587407 |
Biddinger SB et al.:
Hepatic insulin resistance directly promotes formation of cholesterol gallstones
Nat. Med.
2008
14: 778-782
|
| 16446356 |
Cariou B et al.:
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice
J. Biol. Chem.
2006
281
|
| 22871870 |
Carnethon MR et al.:
Association of weight status with mortality in adults with incident diabetes
JAMA
2012
308: 581-590
|
| 21991404 |
Li T et al.:
Bile Acid signaling in liver metabolism and diseases
J Lipids
2012
2012
|
| 18682704 |
Shaham O et al.:
Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity
Mol. Syst. Biol.
2008
4: 214
|
| 22885922 |
Morris AP et al.:
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Nat. Genet.
2012
44: 981-990
|
| 22885924 |
Scott RA et al.:
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Nat. Genet.
2012
44: 991-1005
|
| 22584726 |
Kang HP et al.:
Integration of disease-specific single nucleotide polymorphisms, expression quantitative trait loci and coexpression networks reveal novel candidate genes for type 2 diabetes
Diabetologia
2012
55: 2205-2213
|
| 20060466 |
Renga B et al.:
The bile acid sensor FXR regulates insulin transcription and secretion
Biochim. Biophys. Acta
2010
1802: 363-372
|
| 17200418 |
Fang Y et al.:
Conjugated bile acids regulate hepatocyte glycogen synthase activity in vitro and in vivo via Galphai signaling
Mol. Pharmacol.
2007
71: 1122-1128
|
| 20305288 |
Cao R et al.:
Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via G(alpha)i-protein-coupled receptors and the AKT pathway
J. Lipid Res.
2010
51: 2234-2244
|
| 16400329 |
Watanabe M et al.:
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
Nature
2006
439: 484-489
|
| 22952571 |
Watanabe M et al.:
Bile Acid Binding Resin Improves Metabolic Control through the Induction of Energy Expenditure
PLoS ONE
2012
7
|
| 21680746 |
Liaset B et al.:
Nutritional regulation of bile acid metabolism is associated with improved pathological characteristics of the metabolic syndrome
J. Biol. Chem.
2011
286
|
| 22666533 |
Harach T et al.:
TGR5 potentiates GLP-1 secretion in response to anionic exchange resins
Sci Rep
2012
2: 430
|
| 21941681 |
Brenta G et al.:
Why can insulin resistance be a natural consequence of thyroid dysfunction?
J Thyroid Res
2011
2011
|
| 2173672 |
Abildgaard U et al.:
Monitoring therapy with LMW heparin: a comparison of three chromogenic substrate assays and the Heptest clotting assay
Haemostasis
1990
20: 193-203
|
| 21431855 |
Prawitt J et al.:
Bile acid metabolism and the pathogenesis of type 2 diabetes
Curr Diab Rep
2011
11: 160-166
|
| 22187656 |
Fuchs M et al.:
Non-alcoholic Fatty liver disease: the bile Acid-activated farnesoid x receptor as an emerging treatment target
J Lipids
2012
2012
|
| 23010998 |
Wang-Sattler R et al.:
Novel biomarkers for pre-diabetes identified by metabolomics
Mol. Syst. Biol.
2012
8: 615
|
| 23010998 |
Wang-Sattler R et al.:
Novel biomarkers for pre-diabetes identified by metabolomics
Mol. Syst. Biol.
2012
8: 615
|
| 19577614 |
Gutgesell A et al.:
Mouse carnitine-acylcarnitine translocase (CACT) is transcriptionally regulated by PPARalpha and PPARdelta in liver cells
Biochim. Biophys. Acta
2009
1790: 1206-1216
|
| 17956307 |
Newsholme P et al.:
Amino acid metabolism, insulin secretion and diabetes
Biochem. Soc. Trans.
2007
35: 1180-1186
|
| 22108437 |
Prentki M et al.:
Glycerolipid/free fatty acid cycle and islet beta-cell function in health, obesity and diabetes
Mol. Cell. Endocrinol.
2012
353: 88-100
|
| 22338038 |
Floegel A et al.:
Coffee consumption and risk of chronic disease in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Germany study
Am. J. Clin. Nutr.
2012
95: 901-908
|
| 22458694 |
Natella F et al.:
Role of coffee in modulation of diabetes risk
Nutr. Rev.
2012
70: 207-217
|
| 21346100 |
Gavrieli A et al.:
Caffeinated coffee does not acutely affect energy intake, appetite, or inflammation but prevents serum cortisol concentrations from falling in healthy men
J. Nutr.
2011
141: 703-707
|
| 22970234 |
Xu D et al.:
Caffeine-induced activated glucocorticoid metabolism in the hippocampus causes hypothalamic-pituitary-adrenal axis inhibition in fetal rats
PLoS ONE
2012
7
|
| 22583948 |
Liu Y et al.:
Fetal rat metabonome alteration by prenatal caffeine ingestion probably due to the increased circulatory glucocorticoid level and altered peripheral glucose and lipid metabolic pathways
Toxicol. Appl. Pharmacol.
2012
262: 205-216
|
| 20206259 |
Veilleux A et al.:
Expression of genes related to glucocorticoid action in human subcutaneous and omental adipose tissue
J. Steroid Biochem. Mol. Biol.
2010
122: 28-34
|
| 20840260 |
Kanaka-Gantenbein C et al.:
Fetal origins of adult diabetes
Ann. N. Y. Acad. Sci.
2010
1205: 99-105
|
| 20036327 |
Baptiste CG et al.:
Insulin and hyperandrogenism in women with polycystic ovary syndrome
J. Steroid Biochem. Mol. Biol.
2010
122: 42-52
|
| 21151128 |
Chen ZJ et al.:
Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3
Nat. Genet.
2011
43: 55-59
|
| 22885925 |
Shi Y et al.:
Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome
Nat. Genet.
2012
44: 1020-1025
|
| 21444075 |
Ewens KG et al.:
Type 2 diabetes susceptibility single-nucleotide polymorphisms are not associated with polycystic ovary syndrome
Fertil. Steril.
2011
95: 2538-2541
|
| 22953622 |
Jakubowicz D et al.:
The link between polycystic ovarian syndrome and type 2 diabetes: preventive and therapeutic approach in Israel
Isr. Med. Assoc. J.
2012
14: 442-447
|
| 19846797 |
Wile DJ et al.:
Association of metformin, elevated homocysteine, and methylmalonic acid levels and clinically worsened diabetic peripheral neuropathy
Diabetes Care
2010
33: 156-161
|
| 21960995 |
Chauhan G et al.:
Common variants of homocysteine metabolism pathway genes and risk of type 2 diabetes and related traits in Indians
Exp Diabetes Res
2012
2012
|
| 11473077 |
Meigs JB et al.:
Fasting plasma homocysteine levels in the insulin resistance syndrome: the Framingham offspring study
Diabetes Care
2001
24: 1403-1410
|
| 17898092 |
Brazionis L et al.:
Homocysteine and diabetic retinopathy
Diabetes Care
2008
31: 50-56
|
| 12774164 |
Looker HC et al.:
Homocysteine as a risk factor for nephropathy and retinopathy in Type 2 diabetes
Diabetologia
2003
46: 766-772
|
| 22209966 |
Yun KU et al.:
Plasma homocysteine level and hepatic sulfur amino acid metabolism in mice fed a high-fat diet
Eur J Nutr
2013
52: 127-134
|
| 19937354 |
Russo GT et al.:
Mild hyperhomocysteinemia, C677T polymorphism on methylenetetrahydrofolate reductase gene and the risk of macroangiopathy in type 2 diabetes: a prospective study
Acta Diabetol
2011
48: 95-101
|
| 18780770 |
Sen U et al.:
Ciglitazone, a PPARgamma agonist, ameliorates diabetic nephropathy in part through homocysteine clearance
Am. J. Physiol. Endocrinol. Metab.
2008
295
|
| 12930236 |
Passaro A et al.:
Effect of metabolic control on homocysteine levels in type 2 diabetic patients: a 3-year follow-up
J. Intern. Med.
2003
254: 264-271
|
| 21942443 |
Rahimi Z et al.:
Interaction of MTHFR 1298C with ACE D allele augments the risk of diabetic nephropathy in Western Iran
DNA Cell Biol.
2012
31: 553-559
|
| 20926035 |
Chen AR et al.:
C-reactive protein, vitamin B12 and C677T polymorphism of N-5,10-methylenetetrahydrofolate reductase gene are related to insulin resistance and risk factors for metabolic syndrome in Chinese population
Clin Invest Med
2010
33: E290-E297
|
| 21729881 |
Major JM et al.:
Genome-wide association study identifies common variants associated with circulating vitamin E levels
Hum. Mol. Genet.
2011
20: 3876-3883
|
| 7580706 |
Salonen JT et al.:
Increased risk of non-insulin dependent diabetes mellitus at low plasma vitamin E concentrations: a four year follow up study in men
BMJ
1995
311: 1124-1127
|
| 18776911 |
Hazra A et al.:
Common variants of FUT2 are associated with plasma vitamin B12 levels
Nat. Genet.
2008
40: 1160-1162
|
| 22124606 |
Othman A et al.:
Plasma deoxysphingolipids: a novel class of biomarkers for the metabolic syndrome
Diabetologia
2012
55: 421-431
|
| 22124606 |
Othman A et al.:
Plasma deoxysphingolipids: a novel class of biomarkers for the metabolic syndrome? }, authors { names std { { name ml Othman A, affil str Institute for Clinical Chemistry, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
Diabetologia
2012
55: 421-431
|
| 22460264 |
Vaya A et al.:
Homocysteine levels in morbidly obese patients: its association with waist circumference and insulin resistance
Clin. Hemorheol. Microcirc.
2012
52: 49-56
|
| 10747342 |
Hoogeveen EK et al.:
Hyperhomocysteinemia increases risk of death, especially in type 2 diabetes : 5-year follow-up of the Hoorn Study
Circulation
2000
101: 1506-1511
|
| 19002105 |
Kawai T et al.:
PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta
Lab. Invest.
2009
89: 47-58
|
| 17190910 |
Ohga S et al.:
Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation
Am. J. Physiol. Renal Physiol.
2007
292
|
| 18388116 |
Ko GJ et al.:
Pioglitazone attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats
Nephrol. Dial. Transplant.
2008
23: 2750-2760
|
| 16609149 |
Rodriguez WE et al.:
Pioglitazone mitigates renal glomerular vascular changes in high-fat, high-calorie-induced type 2 diabetes mellitus
Am. J. Physiol. Renal Physiol.
2006
291: F694-F701
|
| 7647779 |
Frosst P et al.:
A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase
Nat. Genet.
1995
10: 111-113
|
| 17879211 |
Rysz J et al.:
Serum matrix metalloproteinases MMP-2 and MMP-9 and metalloproteinase tissue inhibitors TIMP-1 and TIMP-2 in diabetic nephropathy
J Nephrol
2007
20: 444-452
|
| 18690293 |
Rodriguez WE et al.:
PPAR gamma agonist normalizes glomerular filtration rate, tissue levels of homocysteine, and attenuates endothelial-myocyte uncoupling in alloxan induced diabetic mice
Int. J. Biol. Sci.
2008
4: 236-244
|
| 17999084 |
Golledge J et al.:
Relationship between two sequence variations in the gene for peroxisome proliferator-activated receptor-gamma and plasma homocysteine concentration. Health in men study
Hum. Genet.
2008
123: 35-40
|
| 17331860 |
Sahin M et al.:
Effects of metformin or rosiglitazone on serum concentrations of homocysteine, folate, and vitamin B12 in patients with type 2 diabetes mellitus
J. Diabetes Complicat.
2007
21: 118-123
|
| 15691882 |
Najib S et al.:
Homocysteine thiolactone inhibits insulin-stimulated DNA and protein synthesis: possible role of mitogen-activated protein kinase (MAPK), glycogen synthase kinase-3 (GSK-3) and p70 S6K phosphorylation
J. Mol. Endocrinol.
2005
34: 119-126
|
| 21504583 |
Bravo E et al.:
High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway
Lipids Health Dis
2011
10: 60
|
| 20133274 |
Zafiropoulos A et al.:
Paraoxonase 1 R/Q alleles are associated with differential accumulation of saturated versus 20:5n3 fatty acid in human adipose tissue
J. Lipid Res.
2010
51: 1991-2000
|
| 21423183 |
Wang TJ et al.:
Metabolite profiles and the risk of developing diabetes
Nat. Med.
2011
17: 448-453
|
| 20076942 |
Tai ES et al.:
Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men
Diabetologia
2010
53: 757-767
|
| 20093359 |
Herman MA et al.:
Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels
J. Biol. Chem.
2010
285
|
| 20093359 |
Herman MA et al.:
Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels
J. Biol. Chem.
2010
15
|
| 10905472 |
Kelley DE et al.:
Fuel selection in human skeletal muscle in insulin resistance: a reexamination
Diabetes
2000
49: 677-683
|
| 22855696 |
Bhat G et al.:
Life style modification improves insulin resistance and liver histology in patients with non-alcoholic fatty liver disease
World J Hepatol
2012
4: 209-217
|
| 15983191 |
Sparks LM et al.:
A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle
Diabetes
2005
54: 1926-1933
|
| 22065088 |
Shah SH et al.:
Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss
Diabetologia
2012
2: 321-330
|
| 21525399 |
Laferrere B et al.:
Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss
Sci Transl Med
2011
80: 80re2
|
| 20959535 |
Hsiao G et al.:
Multi-tissue, selective PPARgamma modulation of insulin sensitivity and metabolic pathways in obese rats
Am. J. Physiol. Endocrinol. Metab.
2011
300: E164-E174
|
| 18765678 |
Avruch J et al.:
Amino acid regulation of TOR complex 1
Am. J. Physiol. Endocrinol. Metab.
2009
4: E592-E602
|
| 21282364 |
Xiao F et al.:
Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways
Diabetes
2011
60: 746-756
|
| 21731668 |
Macotela Y et al.:
Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism
PLoS ONE
2011
6
|
| 18541149 |
Kuzuya T et al.:
Regulation of branched-chain amino acid catabolism in rat models for spontaneous type 2 diabetes mellitus
Biochem. Biophys. Res. Commun.
2008
373: 94-98
|
| 17925455 |
She P et al.:
Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism
Am. J. Physiol. Endocrinol. Metab.
2007
293
|
| 17925455 |
She P et al.:
Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism
Am. J. Physiol. Endocrinol. Metab.
2007
6
|
| 10720037 |
Ahren B et al.:
Antidiabetogenic action of cholecystokinin-8 in type 2 diabetes
J. Clin. Endocrinol. Metab.
2000
85: 1043-1048
|
| 16827595 |
Aguilar D et al.:
ACE inhibitors and angiotensin receptor antagonists and the incidence of new-onset diabetes mellitus: an emerging theme
Drugs
2006
66: 1169-1177
|
| 17398202 |
Andraws R et al.:
Effect of inhibition of the renin-angiotensin system on development of type 2 diabetes mellitus (meta-analysis of randomized trials)
Am. J. Cardiol.
2007
99: 1006-1012
|
| 11406494 |
Cyr M et al.:
Bradykinin and des-Arg(9)-bradykinin metabolic pathways and kinetics of activation of human plasma
Am. J. Physiol. Heart Circ. Physiol.
2001
281: H275-H283
|
| 23160531 |
Patel SG et al.:
Pathogenesis of A(-)beta(+) ketosis-prone diabetes
Diabetes
2013
62: 912-922
|
| 22611441 |
Smiley D et al.:
Update on diagnosis, pathogenesis and management of ketosis-prone Type 2 diabetes mellitus
Diabetes Manag (Lond)
2011
1: 589-600
|
| 18292467 |
Balasubramanyam A et al.:
Syndromes of ketosis-prone diabetes mellitus
Endocr. Rev.
2008
29: 292-302
|
| 19317510 |
Chorell E et al.:
Predictive metabolomics evaluation of nutrition-modulated metabolic stress responses in human blood serum during the early recovery phase of strenuous physical exercise
J. Proteome Res.
2009
8: 2966-2977
|
| 23289647 |
de Lorgeril M et al.:
Recent findings on the health effects of omega-3 fatty acids and statins, and their interactions: do statins inhibit omega-3
BMC Med
2013
11: 5
|
| 11434193 |
Rise P et al.:
Statins enhance arachidonic acid synthesis in hypercholesterolemic patients
Nutr Metab Cardiovasc Dis
2001
11: 88-94
|
| 16020749 |
Jula A et al.:
Effects of diet and simvastatin on fatty acid composition in hypercholesterolemic men: a randomized controlled trial
Arterioscler. Thromb. Vasc. Biol.
2005
25: 1952-1959
|
| 19458390 |
Ohta T et al.:
Untargeted metabolomic profiling as an evaluative tool of fenofibrate-induced toxicology in Fischer 344 male rats
Toxicol Pathol
2009
37: 521-535
|
| 19166731 |
Li X et al.:
Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for metabonomics: Biomarker discovery for diabetes mellitus
Anal. Chim. Acta
2009
2: 257-262
|
| 21649438 |
Diaz SO et al.:
Metabolic biomarkers of prenatal disorders: an exploratory NMR metabonomics study of second trimester maternal urine and blood plasma
J. Proteome Res.
2011
10: 3732-3742
|
| 20526369 |
Gall WE et al.:
alpha-hydroxybutyrate is an early biomarker of insulin resistance and glucose intolerance in a nondiabetic population
PLoS ONE
2010
5
|
| 22941588 |
Matikainen N et al.:
Management of dyslipidemias in the presence of the metabolic syndrome or type 2 diabetes
Curr Cardiol Rep
2012
14: 721-731
|
| 23150726 |
Ringseis R et al.:
Regulation of Genes Involved in Carnitine Homeostasis by PPARalpha across Different Species (Rat, Mouse, Pig, Cattle, Chicken, and Human)
PPAR Res
2012
2012
|
| 22343897 |
Ichimura A et al.:
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
Nature
2012
483: 350-354
|
| 22343897 |
Ichimura A et al.:
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
Nature
2012
483: 350-354
|
| 21966444 |
Ibrahim MM et al.:
Chronic consumption of farmed salmon containing persistent organic pollutants causes insulin resistance and obesity in mice
PLoS ONE
2011
6
|
| 22231607 |
Culver AL et al.:
Statin use and risk of diabetes mellitus in postmenopausal women in the Womens Health Initiative
Arch. Intern. Med.
2012
172: 144-152
|
| 20064776 |
Ruzzin J et al.:
Persistent organic pollutant exposure leads to insulin resistance syndrome
Environ. Health Perspect.
2010
118: 465-471
|
| 16393666 |
Alonso-Magdalena P et al.:
The estrogenic effect of bisphenol A disrupts pancreatic beta-cell function in vivo and induces insulin resistance
Environ. Health Perspect.
2006
114: 106-112
|
| 22852093 |
Shankar A et al.:
Urinary bisphenol a levels and measures of obesity: results from the national health and nutrition examination survey 2003-2008
ISRN Endocrinol
2012
2012
|
| 16801591 |
Lee DH et al.:
A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002
Diabetes Care
2006
29: 1638-1644
|
| 20298928 |
Koh KK et al.:
Atorvastatin causes insulin resistance and increases ambient glycemia in hypercholesterolemic patients
J. Am. Coll. Cardiol.
2010
55: 1209-1216
|
| 23449848 |
Al-Azzam SI et al.:
Effect of statin therapy on vaspin levels in type 2 diabetic patients
Clin Pharmacol
2013
5: 33-38
|
| 15914273 |
Duncan RE et al.:
Regulation of HMG-CoA reductase in MCF-7 cells by genistein, EPA, and DHA, alone and in combination with mevastatin
Cancer Lett.
2005
224: 221-228
|
| 22399524 |
Babu PV et al.:
Genistein prevents hyperglycemia-induced monocyte adhesion to human aortic endothelial cells through preservation of the cAMP signaling pathway and ameliorates vascular inflammation in obese diabetic mice
J. Nutr.
2012
142: 724-730
|
| 22117528 |
Tsai SJ et al.:
Anti-inflammatory and antifibrotic effects of naringenin in diabetic mice
J. Agric. Food Chem.
2012
60: 514-521
|
| 19592617 |
Mulvihill EE et al.:
Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance
Diabetes
2009
58: 2198-2210
|
| 20811644 |
Goldwasser J et al.:
Transcriptional regulation of human and rat hepatic lipid metabolism by the grapefruit flavonoid naringenin: role of PPARalpha, PPARgamma and LXRalpha
PLoS ONE
2010
5
|
| 22892813 |
Desideri G et al.:
Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: the Cocoa, Cognition, and Aging (CoCoA) study
Hypertension
2012
60: 794-801
|
| 22948221 |
Alonso-Castro AJ et al.:
Isoorientin reverts TNF-alpha-induced insulin resistance in adipocytes activating the insulin signaling pathway
Endocrinology
2012
153: 5222-5230
|
| 22810991 |
Barona J et al.:
Grape polyphenols reduce blood pressure and increase flow-mediated vasodilation in men with metabolic syndrome
J. Nutr.
2012
142: 1626-1632
|
| 16483743 |
Huong DT et al.:
Activity and mRNA levels of enzymes involved in hepatic fatty acid oxidation in mice fed citrus flavonoids
Nutrition
2006
22: 546-552
|
| 22503922 |
Joven J et al.:
Plant-derived polyphenols regulate expression of miRNA paralogs miR-103/107 and miR-122 and prevent diet-induced fatty liver disease in hyperlipidemic mice
Biochim. Biophys. Acta
2012
1820: 894-899
|
| 22471389 |
Kim GS et al.:
Citrus aurantium flavonoids inhibit adipogenesis through the Akt signaling pathway in 3T3-L1 cells
BMC Complement Altern Med
2012
12: 31
|
| 18690615 |
Liu L et al.:
Naringenin and hesperetin, two flavonoids derived from Citrus aurantium up-regulate transcription of adiponectin
Phytother Res
2008
22: 1400-1403
|
| 19233159 |
Montenegro MF et al.:
Isoflavone genistein inhibits the angiotensin-converting enzyme and alters the vascular responses to angiotensin I and bradykinin
Eur. J. Pharmacol.
2009
607: 173-177
|
| 20976215 |
Lucio M et al.:
Insulin sensitivity is reflected by characteristic metabolic fingerprints--a Fourier transform mass spectrometric non-targeted metabolomics approach
PLoS ONE
2010
10
|
| 21170321 |
Fiehn O et al.:
Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women
PLoS ONE
2010
5
|
| 21085649 |
Suhre K et al.:
Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting
PLoS ONE
2010
5
|
| 22776444 |
Ivorra C et al.:
Metabolomic profiling in blood from umbilical cords of low birth weight newborns
J Transl Med
2012
10: 142
|
| 14746561 |
Eriksson M et al.:
Birth weight and cardiovascular risk factors in a cohort followed until 80 years of age: the study of men born in 1913
J. Intern. Med.
2004
255: 236-246
|
| 16502489 |
Kim CS et al.:
The relation between birth weight and insulin resistance in Korean adolescents
Yonsei Med. J.
2006
47: 85-92
|
| 12941711 |
Hypponen E et al.:
Prenatal growth, BMI, and risk of type 2 diabetes by early midlife
Diabetes Care
2003
26: 2512-2517
|
| 10068385 |
Rich-Edwards JW et al.:
Birthweight and the risk for type 2 diabetes mellitus in adult women
Ann. Intern. Med.
1999
130: 278-284
|
| 15729577 |
Ozanne SE et al.:
Low birthweight is associated with specific changes in muscle insulin-signalling protein expression
Diabetologia
2005
48: 547-552
|
| 23285025 |
Sachse D et al.:
Metabolic changes in urine during and after pregnancy in a large, multiethnic population-based cohort study of gestational diabetes
PLoS ONE
2012
7
|
| 23228723 |
Tomi M et al.:
Early life nutrient restriction impairs blood-brain metabolic profile and neurobehavior predisposing to Alzheimers disease with aging
Brain Res.
2013
1495: 61-75
|
| 17488363 |
van Doorn M et al.:
Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in Type 2 diabetes mellitus patients and healthy volunteers
Br J Clin Pharmacol
2007
63: 562-574
|
| 11788666 |
Bajoria R et al.:
Placenta as a link between amino acids, insulin-IGF axis, and low birth weight: evidence from twin studies
J. Clin. Endocrinol. Metab.
2002
87: 308-315
|
| 20212498 |
Calvani R et al.:
Gut microbiome-derived metabolites characterize a peculiar obese urinary metabotype
Int J Obes (Lond)
2010
34: 1095-1098
|
| 17190852 |
Salek RM et al.:
A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human
Physiol. Genomics
2007
29: 99-108
|
| 23497837 |
Lukaschek K et al.:
Relationship between posttraumatic stress disorder and type 2 diabetes in a population-based cross-sectional study with 2970 participants
J Psychosom Res
2013
74: 340-345
|
| 20567778 |
Connor SC et al.:
Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes
Mol Biosyst
2010
6: 909-921
|
| 20567778 |
Connor SC et al.:
Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes
Mol Biosyst
2010
5: 909-921
|
| 16298335 |
Kloting N et al.:
Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes
Biochem. Biophys. Res. Commun.
2006
339: 430-436
|
| 18726871 |
Kempf K et al.:
Vaspin (SERPINA12) genotypes and risk of type 2 diabetes: Results from the MONICA/KORA studies
Exp. Clin. Endocrinol. Diabetes
2010
118: 184-189
|
| 19011679 |
Jensen CB et al.:
Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight
PLoS ONE
2008
3: E3738
|
| 18336063 |
Pietilainen KH et al.:
Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity
PLoS Med.
2008
5: E51
|
| 20814537 |
Nissen PM et al.:
Metabolomics reveals relationship between plasma inositols and birth weight: possible markers for fetal programming of type 2 diabetes
|
| 16127779 |
Jung TS et al.:
Determination of urinary Myo-/chiro-inositol ratios from Korean diabetes patients
Yonsei Med. J.
2005
46: 532-538
|
| 23016130 |
Cormier H et al.:
Association between polymorphisms in the fatty acid desaturase gene cluster and the plasma triacylglycerol response to an n-3 PUFA supplementation
Nutrients
2012
4: 1026-1041
|
| 22479202 |
Dastani Z et al. et al.:
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
PLoS Genet
2012
8
|
| 19557161 |
Lindgren CM et al.:
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution
PLoS Genet.
2009
5
|
| 20686565 |
Teslovich TM et al.:
Biological, clinical and population relevance of 95 loci for blood lipids
Nature
2010
466: 707-713
|
| 17804763 |
Aulchenko YS et al.:
LPIN2 is associated with type 2 diabetes, glucose metabolism, and body composition
Diabetes
2007
56: 3020-3026
|
| 19136718 |
Gropler MC et al.:
Lipin 2 is a liver-enriched phosphatidate phosphohydrolase enzyme that is dynamically regulated by fasting and obesity in mice
J. Biol. Chem.
2009
284: 6763-6772
|
| 21423719 |
Speliotes EK et al.:
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits
PLoS Genet.
2011
7
|
| 22286219 |
Kettunen J et al.:
Genome-wide association study identifies multiple loci influencing human serum metabolite levels
Nat. Genet.
2012
44: 269-276
|
| 19043545 |
Gieger C et al.:
Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum
PLoS Genet.
2008
4
|
| 21211036 |
Hornbak M et al.:
The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load
BMC Med. Genet.
2011
12: 4
|
| 11489939 |
Clayton PT et al.:
Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion
J. Clin. Invest.
2001
108: 457-465
|
| 18567820 |
Grarup N et al.:
Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes
Diabetes
2008
57: 2534-2540
|
| 22485135 |
Kelly MA et al.:
Circadian gene variants and susceptibility to type 2 diabetes: a pilot study
PLoS ONE
2012
7
|
| 22456796 |
Imamura M et al.:
A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations
Hum. Mol. Genet.
2012
21: 3042-3049
|
| 22581228 |
Manning AK et al. et al.:
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
Nat. Genet.
2012
44: 659-669
|
| 20693352 |
Nettleton JA et al.:
Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies
Diabetes Care
2010
33: 2684-2691
|
| 22325160 |
Saxena R et al.:
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
Am. J. Hum. Genet.
2012
90: 410-425
|
| 21873549 |
Strawbridge RJ et al.:
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
Diabetes
2011
60: 2624-2634
|
| 22693455 |
Perry JR et al.:
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases
PLoS Genet.
2012
8
|
| 19933169 |
Perry JR et al.:
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes
Hum. Mol. Genet.
2010
19: 535-544
|
| 22238593 |
Palmer ND et al.:
A genome-wide association search for type 2 diabetes genes in African Americans
PLoS ONE
2012
7
|
| 16873704 |
Yokoi N et al.:
Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects
Diabetes
2006
55: 2379-2386
|
| 21814490 |
Zhang H et al.:
Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation
PLoS Biol.
2011
9
|
| 12215445 |
Grosfeld A et al.:
Hypoxia-inducible factor 1 transactivates the human leptin gene promoter
J. Biol. Chem.
2002
277
|
| 19285836 |
Starrenburg FC et al.:
How can antipsychotics cause Diabetes Mellitus? Insights based on receptor-binding profiles, humoral factors and transporter proteins
Eur. Psychiatry
2009
24: 164-170
|
| 20175225 |
Pfaffly J et al.:
Leptin increases striatal dopamine D2 receptor binding in leptin-deficient obese (ob/ob) mice
Synapse
2010
64: 503-510
|
| 8770873 |
De Vos P et al.:
Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma
J. Clin. Invest.
1996
98: 1004-1009
|
| 8643605 |
Miller SG et al.:
The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression
Proc. Natl. Acad. Sci. U.S.A.
1996
93: 5507-5511
|
| 16096055 |
Gunton JE et al.:
Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes
Cell
2005
122: 337-349
|
| 20440072 |
Cheng K et al.:
Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets
J. Clin. Invest.
2010
120: 2171-2183
|
| 22051049 |
Ochiai D et al.:
Disruption of HIF-1alpha in hepatocytes impairs glucose metabolism in diet-induced obesity mice
Biochem. Biophys. Res. Commun.
2011
415: 445-449
|
| 21873554 |
Jiang C et al.:
Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice
Diabetes
2011
60: 2484-2495
|
| 22302938 |
Krishnan J et al.:
Dietary obesity-associated Hif1alpha activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system
Genes Dev.
2012
26: 259-270
|
| 22302938 |
Krishnan J et al.:
Dietary obesity-associated Hif1alpha activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system
Genes Dev.
2012
26: 259-270
|
| 15220195 |
Duttaroy A et al.:
Muscarinic stimulation of pancreatic insulin and glucagon release is abolished in m3 muscarinic acetylcholine receptor-deficient mice
Diabetes
2004
53: 1714-1720
|
| 21078968 |
Kong KC et al.:
M3-muscarinic receptor promotes insulin release via receptor phosphorylation/arrestin-dependent activation of protein kinase D1
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 16753580 |
Gautam D et al.:
A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo
Cell Metab.
2006
3: 449-461
|
| 21982116 |
Weston-Green K et al.:
Effects of olanzapine on muscarinic M3 receptor binding density in the brain relates to weight gain, plasma insulin and metabolic hormone levels
Eur Neuropsychopharmacol
2012
22: 364-373
|
| 20385802 |
Ruiz de Azua I et al.:
RGS4 is a negative regulator of insulin release from pancreatic beta-cells in vitro and in vivo
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 7999-8004
|
| 23106615 |
Gotoh K et al.:
Nesfatin-1, corticotropin-releasing hormone, thyrotropin-releasing hormone, and neuronal histamine interact in the hypothalamus to regulate feeding behavior
J. Neurochem.
2013
124: 90-99
|
| 21336576 |
Vehof J et al.:
Association of genetic variants of the histamine H1 and muscarinic M3 receptors with BMI and HbA1c values in patients on antipsychotic medication
Psychopharmacology (Berl.)
2011
216: 257-265
|
| 20054193 |
Durand E et al.:
Evaluating the association of FAAH common gene variation with childhood, adult severe obesity and type 2 diabetes in the French population
Obes Facts
2008
1: 305-309
|
| 21569107 |
Abdel Hay RM et al.:
Association between the leptin gene 2548G/A polymorphism, the plasma leptin and the metabolic syndrome with psoriasis
Exp. Dermatol.
2011
20: 715-719
|
| 17268419 |
Ukkola O et al.:
Leu7Pro polymorphism of PreproNPY associated with an increased risk for type II diabetes in middle-aged subjects
Eur J Clin Nutr
2007
61: 1102-1105
|
| 22584873 |
Mutschler J et al.:
Genetic variation in the neuropeptide Y gene promoter is associated with increased risk of tobacco smoking
Eur Addict Res
2012
18: 246-252
|
| 10926322 |
Niskanen L et al.:
Leucine 7 to proline 7 polymorphism in the neuropeptide y gene is associated with retinopathy in type 2 diabetes
Exp. Clin. Endocrinol. Diabetes
2000
108: 235-236
|
| 20065978 |
de Luis DA et al.:
C358A missense polymorphism of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) and visfatin levels in obese females
Int J Obes (Lond)
2010
34: 511-515
|
| 17317762 |
Andrulionyte L et al.:
Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-alpha gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial
Diabetes
2007
56: 1181-1186
|
| 11030756 |
Mammarella S et al.:
Interaction between the G1057D variant of IRS-2 and overweight in the pathogenesis of type 2 diabetes
Hum. Mol. Genet.
2000
9: 2517-2521
|
| 19887537 |
Barbieri M et al.:
The IRS2 Gly1057Asp variant is associated with human longevity
J. Gerontol. A Biol. Sci. Med. Sci.
2010
65: 282-286
|
| 16740635 |
Canto C et al.:
Neuregulins mediate calcium-induced glucose transport during muscle contraction
J. Biol. Chem.
2006
281
|
| 11971667 |
Gonzalez-Bono E et al.:
Glucose but not protein or fat load amplifies the cortisol response to psychosocial stress
Horm Behav
2002
41: 328-333
|
| 23337395 |
Stoynev N et al.:
Gene expression in peripheral blood of patients with hypertension and patients with type 2 diabetes
J Cardiovasc Med (Hagerstown)
2014
15: 702-709
|
| 18258217 |
Santiago AR et al.:
Diabetes changes ionotropic glutamate receptor subunit expression level in the human retina
Brain Res.
2008
1198: 153-159
|
| 17960828 |
Gireesh G et al.:
Decreased muscarinic M1 receptor gene expression in the hypothalamus, brainstem, and pancreatic islets of streptozotocin-induced diabetic rats
J. Neurosci. Res.
2008
86: 947-953
|
| 23624546 |
Boertien WE et al.:
Copeptin, a surrogate marker for arginine vasopressin, is associated with declining glomerular filtration in patients with diabetes mellitus (ZODIAC-33)
Diabetologia
2013
56: 1680-1688
|
| 23275932 |
Chang SA et al.:
Smoking and type 2 diabetes mellitus
Diabetes Metab J
2012
36: 399-403
|
| 18245179 |
Wu RR et al.:
Metformin addition attenuates olanzapine-induced weight gain in drug-naive first-episode schizophrenia patients: a double-blind, placebo-controlled study
Am J Psychiatry
2008
165: 352-358
|
| 12453893 |
Ikezaki A et al.:
Fasting plasma ghrelin levels are negatively correlated with insulin resistance and PAI-1, but not with leptin, in obese children and adolescents
Diabetes
2002
51: 3408-3411
|
| 15070922 |
McLaughlin T et al.:
Plasma ghrelin concentrations are decreased in insulin-resistant obese adults relative to equally obese insulin-sensitive controls
J. Clin. Endocrinol. Metab.
2004
89: 1630-1635
|
| 11739476 |
Wren AM et al.:
Ghrelin enhances appetite and increases food intake in humans
J. Clin. Endocrinol. Metab.
2001
86: 5992
|
| 15491236 |
Arranz B et al.:
Insulin resistance and increased leptin concentrations in noncompliant schizophrenia patients but not in antipsychotic-naive first-episode schizophrenia patients
J Clin Psychiatry
2004
65: 1335-1342
|
| 11775042 |
Hagg S et al.:
Leptin concentrations are increased in subjects treated with clozapine or conventional antipsychotics
J Clin Psychiatry
2001
62: 843-848
|
| 9989571 |
Kraus T et al.:
Body weight and leptin plasma levels during treatment with antipsychotic drugs
Am J Psychiatry
1999
156: 312-314
|
| 11078035 |
Melkersson KI et al.:
Elevated levels of insulin, leptin, and blood lipids in olanzapine-treated patients with schizophrenia or related psychoses
J Clin Psychiatry
2000
61: 742-749
|
| 15666332 |
Ellingrod VL et al.:
Weight gain associated with the -759C/T polymorphism of the 5HT2C receptor and olanzapine
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2005
134B: 76-78
|
| 15167695 |
Ellingrod VL et al.:
Distribution of the serotonin 2C (5HT2C) receptor gene -759C/T polymorphism in patients with schizophrenia and normal controls
Psychiatr. Genet.
2004
14: 93-95
|
| 18192901 |
Iordanidou M et al.:
The -759C/T polymorphism of the 5-HT2C receptor is associated with type 2 diabetes in male and female Caucasians
Pharmacogenet. Genomics
2008
18: 153-159
|
| 16583406 |
Park YM et al.:
Weight gain associated with the alpha2a-adrenergic receptor -1,291 C/G polymorphism and olanzapine treatment
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2006
141B: 394-397
|
| 19193342 |
Ujike H et al.:
Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: a cohort study
J Clin Psychiatry
2008
69: 1416-1422
|
| 19690620 |
Kring SI et al.:
Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes
PLoS ONE
2009
4: E6696
|
| 22391941 |
Jing C et al.:
Meta-analysis of association studies between five candidate genes and type 2 diabetes in Chinese Han population
Endocrine
2012
42: 307-320
|
| 23090266 |
Feng S et al.:
Metabolic parameters and long-term antipsychotic treatment: a comparison between patients treated with clozapine or olanzapine
Neuro Endocrinol. Lett.
2012
33: 493-498
|
| 20393934 |
Salpeter SR et al.:
Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus
Cochrane Database Syst Rev
2010
4:
|
| 22033060 |
Cox K et al.:
Prevalence and significance of lactic acidosis in diabetic ketoacidosis
J Crit Care
2012
27: 132-137
|
| 18571361 |
Perrone J et al.:
Occult metformin toxicity in three patients with profound lactic acidosis
J Emerg Med
2011
40: 271-275
|
| 20846876 |
Myers MG Jr et al.:
Obesity and leptin resistance: distinguishing cause from effect
Trends Endocrinol. Metab.
2010
21: 643-651
|
| 23559402 |
Cabaleiro T et al.:
Polymorphisms influencing olanzapine metabolism and adverse effects in healthy subjects
Hum Psychopharmacol
2013
28: 205-214
|
| 23559402 |
Cabaleiro T et al.:
Polymorphisms influencing olanzapine metabolism and adverse effects in healthy subjects
Hum Psychopharmacol
2013
28: 205-214
|
| 23926289 |
Schmidt RH et al.:
Olanzapine activates hepatic mammalian target of rapamycin: new mechanistic insight into metabolic dysregulation with atypical antipsychotic drugs
J. Pharmacol. Exp. Ther.
2013
347: 126-135
|
| 23446828 |
Xu M et al.:
Genetic determinant for amino acid metabolites and changes in body weight and insulin resistance in response to weight-loss diets: the Preventing Overweight Using Novel Dietary Strategies (POUNDS LOST) trial
Circulation
2013
127: 1283-1289
|
| 22707151 |
Lei J et al.:
Hormonal regulation of leucine catabolism in mammary epithelial cells
Amino Acids
2013
45: 531-541
|
| 3103467 |
Block KP et al.:
Glucocorticoid-mediated activation of muscle branched-chain alpha-keto acid dehydrogenase in vivo
Am. J. Physiol.
1987
252: E396-E407
|
| 649596 |
et al.:
The metabolic fates of amino acids and the formation of glutamine in skeletal muscle
J. Biol. Chem.
1978
253: 3685-3693
|
| 15389298 |
Wijekoon EP et al.:
Amino acid metabolism in the Zucker diabetic fatty rat: effects of insulin resistance and of type 2 diabetes
Can. J. Physiol. Pharmacol.
2004
82: 506-514
|
| 3827880 |
Letto J et al.:
Valine metabolism. Gluconeogenesis from 3-hydroxyisobutyrate
Biochem. J.
1986
240: 909-912
|
| 19411760 |
Lu G et al.:
Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells
J. Clin. Invest.
2009
119: 1678-1687
|
| 12037730 |
Keller U et al.:
Effects of medium- and long-chain fatty acids on whole body leucine and glucose kinetics in man
Metab. Clin. Exp.
2002
51: 754-760
|
| 1974474 |
Pacy PJ et al.:
Influence of glucagon on protein and leucine metabolism: a study in fasting man with induced insulin resistance
Br J Surg
1990
77: 791-794
|
| 17581840 |
Howarth KR et al.:
Exercise training increases branched-chain oxoacid dehydrogenase kinase content in human skeletal muscle
Am. J. Physiol. Regul. Integr. Comp. Physiol.
2007
293
|
| 7320199 |
Aoki TT et al.:
Leucine meal increases glutamine and total nitrogen release from forearm muscle
J. Clin. Invest.
1981
68: 1522-1528
|
| 3963181 |
Gelfand RA et al.:
Removal of infused amino acids by splanchnic and leg tissues in humans
Am. J. Physiol.
1986
250: E407-E413
|
| 1996635 |
Darmaun D et al.:
Role of leucine as a precursor of glutamine alpha-amino nitrogen in vivo in humans
Am. J. Physiol.
1991
2: Pt 1 E326-E329
|
| 9571255 |
Stanley CA et al.:
Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene
N. Engl. J. Med.
1998
338: 1352-1357
|
| 21687978 |
Ingwersen MS et al.:
Na,K-ATPase activity in mouse muscle is regulated by AMPK and PGC-1alpha
J. Membr. Biol.
2011
242: 1-10
|
| 1469091 |
Louard RJ et al.:
Insulin sensitivity of protein and glucose metabolism in human forearm skeletal muscle
J. Clin. Invest.
1992
90: 2348-2354
|
| 6353139 |
author information missing
Influence of insulin on blood levels of branched chain keto and amino acids in man
Metab. Clin. Exp.
1983
4: 323-327
|
| 3965862 |
Schauder P et al.:
Serum branched chain amino and keto acid response to fasting in humans
Metab. Clin. Exp.
1985
34: 58-61
|
| 7840227 |
Mak JC et al.:
Glucocorticosteroids increase beta 2-adrenergic receptor transcription in human lung
Am. J. Physiol.
1995
268: L41-L46
|
| 20829805 |
Prior SJ et al.:
ADRB2 haplotype is associated with glucose tolerance and insulin sensitivity in obese postmenopausal women
Obesity (Silver Spring)
2011
19: 396-401
|
| 23335958 |
SanGiovanni JP et al.:
DNA sequence variants in PPARGC1A, a gene encoding a coactivator of the omega-3 LCPUFA sensing PPAR-RXR transcription complex, are associated with NV AMD and AMD-associated loci in genes of complement and VEGF signaling pathways
PLoS ONE
2013
8
|
| 2837475 |
Collins S et al.:
Beta-adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids
J. Biol. Chem.
1988
263: 9067-9070
|
| 9032216 |
Baraniuk JN et al.:
Glucocorticoids induce beta2-adrenergic receptor function in human nasal mucosa
Am. J. Respir. Crit. Care Med.
1997
155: 704-710
|
| 9873044 |
Eickelberg O et al.:
Ligand-independent activation of the glucocorticoid receptor by beta2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells
J. Biol. Chem.
1999
274: 1005-1010
|
| 11557972 |
Yoon JC et al.:
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
Nature
2001
413: 131-138
|
| 23882149 |
Vaughan RA et al.:
Effects of caffeine on metabolism and mitochondria biogenesis in rhabdomyosarcoma cells compared with 2,4-dinitrophenol
Nutr Metab Insights
2012
5: 59-70
|
| 15024092 |
Cao W et al.:
p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene
Mol. Cell. Biol.
2004
24: 3057-3067
|
| 15964803 |
Robidoux J et al.:
Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes
Mol. Cell. Biol.
2005
25: 5466-5479
|
| 17446185 |
Miura S et al.:
An increase in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to exercise is mediated by beta-adrenergic receptor activation
Endocrinology
2007
148: 3441-3448
|
| 16882880 |
Martinez-Jimenez CP et al.:
Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1
Mol. Pharmacol.
2006
70: 1681-1692
|
| 23930106 |
Yuyun X et al.:
Effects of Low Concentrations of Rotenone upon Mitohormesis in SH-SY5Y Cells
Dose Response
2012
11: 270-280
|
| 24120945 |
Yue J et al.:
Dehydroepiandrosterone-sulfate (DHEAS) promotes MIN6 cells insulin secretion via inhibition of AMP-activated protein kinase
Biochem. Biophys. Res. Commun.
2013
440: 756-761
|
| 19650880 |
Tajes M et al.:
Anti-aging properties of melatonin in an in vitro murine senescence model: involvement of the sirtuin 1 pathway
J. Pineal Res.
2009
47: 228-237
|
| 16293234 |
Mailliet F et al.:
Characterization of the melatoninergic MT3 binding site on the NRH:quinone oxidoreductase 2 enzyme
Biochem. Pharmacol.
2005
71: 74-88
|
| 19091957 |
Ho TC et al.:
Cytosolic phospholipase A2-{alpha} is an early apoptotic activator in PEDF-induced endothelial cell apoptosis
Am. J. Physiol.
2009
296: C273-C284
|
| 11481440 |
Knutti D et al.:
Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor
Proc. Natl. Acad. Sci. U.S.A.
2001
98: 9713-9718
|
| 9529258 |
Puigserver P et al.:
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
Cell
1998
6: 829-839
|
| 17327465 |
Hu W et al.:
Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro
Mol. Pharmacol.
2007
71: 1475-1486
|
| 15521013 |
Seree E et al.:
Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites
Gastroenterology
2004
127: 1436-1445
|
| 12623754 |
Krusekopf S et al.:
Time-dependent transcriptional induction of CYP1A1, CYP1A2 and CYP1B1 mRNAs by H+/K+ -ATPase inhibitors and other xenobiotics
Xenobiotica
2003
33: 107-118
|
| 14560034 |
Hestermann EV et al.:
Agonist and chemopreventative ligands induce differential transcriptional cofactor recruitment by aryl hydrocarbon receptor
Mol. Cell. Biol.
2003
23: 7920-7925
|
| 14636573 |
Wallberg AE et al.:
Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha
Mol Cell
2003
12: 1137-1149
|
| 11343698 |
Liang YC et al.:
Suppression of inducible cyclooxygenase and nitric oxide synthase through activation of peroxisome proliferator-activated receptor-gamma by flavonoids in mouse macrophages
FEBS Lett.
2001
496: 12-18
|
| 16271822 |
Chaudhary A et al.:
Inhibition of human cytochrome CYP 1 enzymes by flavonoids of St. Johns wort
Toxicology
2006
217: 194-205
|
| 10669761 |
Vega RB et al.:
The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes
Mol. Cell. Biol.
2000
20: 1868-1876
|
| 1959619 |
Majander A et al.:
Electron transfer properties of NADH:ubiquinone reductase in the ND1/3460 and the ND4/11778 mutations of the Leber hereditary optic neuroretinopathy (LHON)
FEBS Lett.
1991
292: 289-292
|
| 10412986 |
Wu Z et al.:
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
Cell
1999
98: 115-124
|
| 23831762 |
Jirkovsky E et al.:
Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits
Toxicology
2013
311: 191-204
|
| 18448419 |
Lu H et al.:
The identification of potential factors associated with the development of type 2 diabetes: a quantitative proteomics approach
Mol Cell Proteomics
2008
7: 1434-1451
|
| 14747290 |
Mitchell KJ et al.:
Role for plasma membrane-related Ca2+-ATPase-1 (ATP2C1) in pancreatic beta-cell Ca2+ homeostasis revealed by RNA silencing
Diabetes
2004
53: 393-400
|
| 23597778 |
Baldelli S et al.:
Punctum on two different transcription factors regulated by PGC-1alpha: nuclear factor erythroid-derived 2-like 2 and nuclear respiratory factor 2
Biochim. Biophys. Acta
2013
1830: 4137-4146
|
| 19527224 |
Lai P et al.:
Changes in expression and activity of the secretory pathway Ca2+ ATPase 1 (SPCA1) in A7r5 vascular smooth muscle cells cultured at different glucose concentrations
Biosci. Rep.
2009
29: 397-404
|
| 22648723 |
Johansson LE et al.:
Differential gene expression in adipose tissue from obese human subjects during weight loss and weight maintenance
Am. J. Clin. Nutr.
2012
96: 196-207
|
| 22179025 |
Edgel KA et al.:
Obesity and weight loss result in increased adipose tissue ABCG1 expression in db/db mice
Biochim. Biophys. Acta
2012
1821: 425-434
|
| 15878932 |
Jorgensen SB et al.:
Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle
FASEB J.
2005
19: 1146-1148
|
| 20614849 |
Nikonova EV et al.:
Changes in components of energy regulation in mouse cortex with increases in wakefulness
Sleep
2010
33: 889-900
|
| 22095692 |
Johri A et al.:
Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntingtons disease
Hum. Mol. Genet.
2012
21: 1124-1137
|
| 16168052 |
Tenenbaum A et al.:
Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons
Cardiovasc Diabetol
2005
4: 14
|
| 17476214 |
Liu C et al.:
Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism
Nature
2007
7143: 477-481
|
| 21216827 |
Howarth FC et al.:
Changing pattern of gene expression is associated with ventricular myocyte dysfunction and altered mechanisms of Ca2+ signalling in young type 2 Zucker diabetic fatty rat heart
Exp. Physiol.
2011
96: 325-337
|
| 17477345 |
Wang G et al.:
Regulation of Na,K-ATPase alpha1 subunit gene transcription in response to low K(+): role of CRE/ATF- and GC box-binding proteins
J. Cell. Physiol.
2007
213: 167-176
|
| 23610133 |
South JC et al.:
The neuregulin system of ligands and their receptors in rat islets of langerhans
Endocrinology
2013
154: 2385-2392
|
| 19251035 |
Genua M et al.:
c-Abl and insulin receptor signalling
Vitam. Horm.
2009
80: 77-105
|
| 19491401 |
Karamitri A et al.:
Combinatorial transcription factor regulation of the cyclic AMP-response element on the Pgc-1alpha promoter in white 3T3-L1 and brown HIB-1B preadipocytes
J. Biol. Chem.
2009
284
|
| 17584738 |
Karamanlidis G et al.:
C/EBPbeta reprograms white 3T3-L1 preadipocytes to a Brown adipocyte pattern of gene expression
J. Biol. Chem.
2007
282
|
| 11557984 |
Herzig S et al.:
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
Nature
2001
413: 179-183
|
| 22616931 |
Bazwinsky-Wutschke I et al.:
Phosphorylation of cyclic AMP-response element-binding protein (CREB) is influenced by melatonin treatment in pancreatic rat insulinoma beta-cells (INS-1)
J. Pineal Res.
2012
53: 344-357
|
| 17198537 |
Catala A et al.:
Melatonin-induced gene expression changes and its preventive effects on adriamycin-induced lipid peroxidation in rat liver
J. Pineal Res.
2007
1: 43-49
|
| 23692925 |
Dong H et al.:
Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins
Biochem. Biophys. Res. Commun.
2013
435: 727-732
|
| 22138560 |
Lascaratos G et al.:
Mitochondrial dysfunction in glaucoma: understanding genetic influences
Mitochondrion
2012
12: 202-212
|
| 15258110 |
Choudhary D et al.:
Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1
Drug Metab. Dispos.
2004
32: 840-847
|
| 18196260 |
Helin M et al.:
Phospholipases A2 in normal human conjunctiva and from patients with primary open-angle glaucoma and exfoliation glaucoma
Graefes Arch. Clin. Exp. Ophthalmol.
2008
246: 739-746
|
| 16709925 |
Hazan-Eitan Z et al.:
Induction of Fc gammaRIIA expression in myeloid PLB cells during differentiation depends on cytosolic phospholipase A2 activity and is regulated via activation of CREB by PGE2
Blood
2006
108: 1758-1766
|
| 24192283 |
Shakya-Vaidya S et al.:
Do non-communicable diseases such as hypertension and diabetes associate with primary open-angle glaucoma? Insights from a case-control study in Nepal
Glob Health Action
2013
6: 22636
|
| 23271129 |
Liu J et al.:
Meta-analysis of the effect of KCNQ1 gene polymorphism on the risk of type 2 diabetes
Mol. Biol. Rep.
2013
40: 3557-3567
|
| 19393642 |
Chung AW et al.:
Diabetes modulates capacitative calcium entry and expression of transient receptor potential canonical channels in human saphenous vein
Eur. J. Pharmacol.
2009
613: 114-118
|
| 23650556 |
Blum CA et al.:
Prognostic value of dehydroepiandrosterone-sulfate and other parameters of adrenal function in acute ischemic stroke
PLoS ONE
2013
8
|
| 21533175 |
Zhai G et al.:
Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms
PLoS Genet.
2011
7
|
| 17554624 |
Ward GR et al.:
Glucocorticoids plus opioids up-regulate genes that influence neuronal function
Cell. Mol. Neurobiol.
2007
27: 651-660
|
| 12860387 |
Weissig H et al.:
Three novel spermatogenesis-specific zinc finger genes
FEBS Lett.
2003
547: 61-68
|
| 16960027 |
Cappola AR et al.:
DHEAS levels and mortality in disabled older women: the Womens Health and Aging Study I
J. Gerontol. A Biol. Sci. Med. Sci.
2006
61: 957-962
|
| 11061502 |
Laughlin GA et al.:
Sexual dimorphism in the influence of advanced aging on adrenal hormone levels: the Rancho Bernardo Study
J. Clin. Endocrinol. Metab.
2000
85: 3561-3568
|
| 11427700 |
Mazat L et al.:
Prospective measurements of dehydroepiandrosterone sulfate in a cohort of elderly subjects: relationship to gender, subjective health, smoking habits, and 10-year mortality
Proc. Natl. Acad. Sci. U.S.A.
2001
98: 8145-8150
|
| 9215295 |
Paolisso G et al.:
Serum levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 in healthy centenarians: relationship with plasma leptin and lipid concentrations, insulin action, and cognitive function
J. Clin. Endocrinol. Metab.
1997
82: 2204-2209
|
| 19389810 |
Grasfeder LL et al.:
Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha
Mol. Endocrinol.
2009
8: 1171-1182
|
| 19389810 |
Grasfeder LL et al.:
Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha
Mol. Endocrinol.
2009
23: 1171-1182
|
| 19762543 |
He J et al.:
Minireview: Nuclear receptor-controlled steroid hormone synthesis and metabolism
Mol. Endocrinol.
2010
1: 11-21
|
| 24205079 |
Hu Z et al.:
Hormonal regulation of microRNA expression in steroid producing cells of the ovary, testis and adrenal gland
PLoS ONE
2013
8
|
| 22526609 |
Abbasi A et al.:
Sex differences in the association between plasma copeptin and incident type 2 diabetes: the Prevention of Renal and Vascular Endstage Disease (PREVEND) study
Diabetologia
2012
55: 1963-1970
|
| 23478411 |
Jain S et al.:
Chronic activation of a designer G(q)-coupled receptor improves beta cell function
J. Clin. Invest.
2013
123: 1750-1762
|
| 21966580 |
Kong KC et al.:
The role of M(3)-muscarinic receptor signaling in insulin secretion
Commun Integr Biol
2011
4: 489-491
|
| 19135240 |
Sumara G et al.:
Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis
Cell
2009
136: 235-248
|
| 24100786 |
Hahn MK et al.:
Acute effects of single-dose olanzapine on metabolic, endocrine, and inflammatory markers in healthy controls
J Clin Psychopharmacol
2013
33: 740-746
|
| 23812432 |
Ozasa R et al.:
The antipsychotic olanzapine induces apoptosis in insulin-secreting pancreatic beta cells by blocking PERK-mediated translational attenuation
Cell Struct. Funct.
2013
38: 183-195
|
| 23856185 |
Girault EM et al.:
Olanzapine-induced changes in glucose metabolism are independent of the melanin-concentrating hormone system
Psychoneuroendocrinology
2013
38: 2640-2646
|
| 17541984 |
Chagnon YC et al.:
Possible association of the pro-melanin-concentrating hormone gene with a greater body mass index as a side effect of the antipsychotic olanzapine
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2007
144
|
| 22730439 |
Ruiz de Azua I et al.:
Spinophilin as a novel regulator of M3 muscarinic receptor-mediated insulin release in vitro and in vivo
FASEB J.
2012
26: 4275-4286
|
| 14985093 |
Zawalich WS et al.:
Effects of muscarinic receptor type 3 knockout on mouse islet secretory responses
Biochem. Biophys. Res. Commun.
2004
315: 872-876
|
| 11242080 |
Yamada M et al.:
Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean
Nature
2001
410: 207-212
|
| 19752163 |
Li JH et al.:
Hepatic muscarinic acetylcholine receptors are not critically involved in maintaining glucose homeostasis in mice
Diabetes
2009
58: 2776-2787
|
| 20843999 |
Gautam D et al.:
Beneficial metabolic effects caused by persistent activation of beta-cell M3 muscarinic acetylcholine receptors in transgenic mice
Endocrinology
2010
151: 5185-5194
|
| 21696923 |
Hahn M et al.:
Atypical antipsychotics and effects of muscarinic, serotonergic, dopaminergic and histaminergic receptor binding on insulin secretion in vivo: an animal model
Schizophr. Res.
2011
131: 90-95
|
| 22733000 |
Sartor F et al.:
Adaptive metabolic response to 4 weeks of sugar-sweetened beverage consumption in healthy, lightly active individuals and chronic high glucose availability in primary human myotubes
Eur J Nutr
2013
52: 937-948
|
| 17998203 |
Chutkow WA et al.:
Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production
J. Biol. Chem.
2008
283: 2397-2406
|
| 23353834 |
Devi TS et al.:
Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: implications for diabetic retinopathy
Exp. Cell Res.
2013
319: 1001-1012
|
| 24037087 |
Jo SH et al.:
Txnip contributes to impaired glucose tolerance by upregulating the expression of genes involved in hepatic gluconeogenesis in mice
Diabetologia
2013
56: 2723-2732
|
| 17472435 |
Parikh H et al.:
TXNIP regulates peripheral glucose metabolism in humans
PLoS Med.
2007
4: E158
|
| 23975026 |
Xu G et al.:
Thioredoxin-interacting protein regulates insulin transcription through microRNA-204
Nat. Med.
2013
19: 1141-1146
|
| 23211392 |
Wu J et al.:
The protective effect of telmisartan in Type 2 diabetes rat kidneys is related to the downregulation of thioredoxin-interacting protein
J. Endocrinol. Invest.
2013
36: 453-459
|
| 23647015 |
Wang W et al.:
Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats
Br. J. Pharmacol.
2013
169: 1352-1371
|
| 18552236 |
Chen J et al.:
Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes
FASEB J.
2008
22: 3581-3594
|
| 21874001 |
Kooner JS et al.:
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci
Nat. Genet.
2011
43: 984-989
|
| 22158537 |
Cho YS et al. et al.:
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians
Nat Genet
2011
44: 67-72
|
| 22315310 |
Kruit JK et al.:
Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired beta-cell function
Diabetes
2012
61: 659-664
|
| 22932913 |
Vitto MF et al.:
Reversion of steatosis by SREBP-1c antisense oligonucleotide did not improve hepatic insulin action in diet-induced obesity mice
Horm. Metab. Res.
2012
44: 885-890
|
| 19411249 |
Cha-Molstad H et al.:
Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells
J. Biol. Chem.
2009
284
|
| 23693076 |
Xue J et al.:
ATP-binding cassette transporter G1 protects against endothelial dysfunction induced by high glucose
|
| 20733269 |
Yamashita M et al.:
Insulin suppresses HDL-mediated cholesterol efflux from macrophages through inhibition of neutral cholesteryl ester hydrolase and ATP-binding cassette transporter G1 expressions
J. Atheroscler. Thromb.
2010
17: 1183-1189
|
| 18490524 |
Mauldin JP et al.:
Reduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitus
Circulation
2008
117: 2785-2792
|
| 22887744 |
Kiffer-Moreira T et al.:
Pharmacological inhibition of PHOSPHO1 suppresses vascular smooth muscle cell calcification
J. Bone Miner. Res.
2013
28: 81-91
|
| 15175005 |
Roberts SJ et al.:
Human PHOSPHO1 exhibits high specific phosphoethanolamine and phosphocholine phosphatase activities
Biochem. J.
2004
382: 59-65
|
| 23179947 |
Wu G et al.:
Choline supplementation promotes hepatic insulin resistance in phosphatidylethanolamine N-methyltransferase-deficient mice via increased glucagon action
J. Biol. Chem.
2013
288: 837-847
|
| 19046568 |
Longuet C et al.:
The glucagon receptor is required for the adaptive metabolic response to fasting
Cell Metab.
2008
8: 359-371
|
| 15494402 |
Kimball SR et al.:
Glucagon represses signaling through the mammalian target of rapamycin in rat liver by activating AMP-activated protein kinase
J. Biol. Chem.
2004
279
|
| 23707907 |
Caillon L et al.:
Evaluation of membrane models and their composition for islet amyloid polypeptide-membrane aggregation
Biochim. Biophys. Acta
2013
1828: 2091-2098
|
| 12609749 |
Akesson B et al.:
Islet amyloid polypeptide inhibits glucagon release and exerts a dual action on insulin release from isolated islets
Regul. Pept.
2003
111: 55-60
|
| 11606473 |
Rushing PA et al.:
Inhibition of central amylin signaling increases food intake and body adiposity in rats
Endocrinology
2001
142: 5035
|
| 9112375 |
Perfetti R et al.:
Overexpression and activation of the insulin receptor enhances expression of ERCC-1 messenger ribonucleic acid in cultured cells
Endocrinology
1997
138: 1829-1835
|
| 19596235 |
Svendsen JM et al.:
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
Cell
2009
138: 63-77
|
| 22590580 |
Song IS et al.:
Pharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin disposition
PLoS ONE
2012
7
|
| 16272756 |
Kimura N et al.:
Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1
Drug Metab. Pharmacokinet.
2005
20: 379-386
|
| 11912245 |
Motohashi H et al.:
Gene expression levels and immunolocalization of organic ion transporters in the human kidney
J. Am. Soc. Nephrol.
2002
13: 866-874
|
| 21970804 |
Kim E et al.:
Inhibition of stearoyl-CoA desaturase1 activates AMPK and exhibits beneficial lipid metabolic effects in vitro
Eur. J. Pharmacol.
2011
672: 38-44
|
| 21478464 |
Kim E et al.:
Metformin inhibits nuclear receptor TR4-mediated hepatic stearoyl-CoA desaturase 1 gene expression with altered insulin sensitivity
Diabetes
2011
60: 1493-1503
|
| 15916750 |
Dobrzyn A et al.:
Polyunsaturated fatty acids do not activate AMP-activated protein kinase in mouse tissues
Biochem. Biophys. Res. Commun.
2005
332: 892-896
|
| 19254698 |
Awazawa M et al.:
Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway
Biochem. Biophys. Res. Commun.
2009
382: 51-56
|
| 23024365 |
Miyamoto L et al.:
Leptin activates hepatic 5-AMP-activated protein kinase through sympathetic nervous system and alpha1-adrenergic receptor: a potential mechanism for improvement of fatty liver in lipodystrophy by leptin
J. Biol. Chem.
2012
287
|
| 15058305 |
Minokoshi Y et al.:
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
Nature
2004
428: 569-574
|
| 15715521 |
Benomar Y et al.:
Cross down-regulation of leptin and insulin receptor expression and signalling in a human neuronal cell line
Biochem. J.
2005
388: 929-939
|
| 21413848 |
Arbo I et al.:
Insulin induces fatty acid desaturase expression in human monocytes
Scand. J. Clin. Lab. Invest.
2011
71: 330-339
|
| 23369366 |
Casado ME et al.:
Hormone-sensitive lipase deficiency disturbs the fatty acid composition of mouse testis
Prostaglandins Leukot. Essent. Fatty Acids
2013
88: 227-233
|
| 12470654 |
Song He W et al.:
Delayed induction of delta-6 and delta-5 desaturases by a peroxisome proliferator
Biochem. Biophys. Res. Commun.
2002
299: 832-838
|
| 11792729 |
Matsuzaka T et al.:
Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha
J. Lipid Res.
2002
1: 107-114
|
| 19876773 |
Ambati S et al.:
Central leptin versus ghrelin: effects on bone marrow adiposity and gene expression
Endocrine
2010
37: 115-123
|
| 21979752 |
Yan K et al.:
p38 mitogen-activated protein kinase and liver X receptor-alpha mediate the leptin effect on sterol regulatory element binding protein-1c expression in hepatic stellate cells
Mol. Med.
2012
18: 10-18
|
| 11546755 |
Tobe K et al.:
Increased expression of the sterol regulatory element-binding protein-1 gene in insulin receptor substrate-2(-/-) mouse liver
J. Biol. Chem.
2001
276
|
| 17823267 |
Gallardo N et al.:
Tissue-specific effects of central leptin on the expression of genes involved in lipid metabolism in liver and white adipose tissue
Endocrinology
2007
148: 5604-5610
|
| 16162944 |
Chang Y et al.:
KGF induces lipogenic genes through a PI3K and JNK/SREBP-1 pathway in H292 cells
J. Lipid Res.
2005
46: 2624-2635
|
| 15135305 |
Holland W et al.:
Metformin (Glucophage) inhibits tyrosine phosphatase activity to stimulate the insulin receptor tyrosine kinase
Biochem. Pharmacol.
2004
67: 2081-2091
|
| 24502834 |
Ahn HR et al.:
The association between liver enzymes and risk of type 2 diabetes: the Namwon study
Diabetol Metab Syndr
2014
6: 14
|
| 17111267 |
Shikata E et al.:
Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin
J. Hum. Genet.
2007
52: 117-122
|
| 20016398 |
Toyama K et al.:
Heterozygous variants of multidrug and toxin extrusions (MATE1 and MATE2-K) have little influence on the disposition of metformin in diabetic patients
Pharmacogenet. Genomics
2010
20: 135-138
|
| 17609683 |
Shu Y et al.:
Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics
Clin. Pharmacol. Ther.
2008
83: 273-280
|
| 23108202 |
Wahl S et al.:
Childhood obesity is associated with changes in the serum metabolite profile
Obes Facts
2012
5: 660-670
|
| 12077728 |
Asagami T et al.:
Metformin treatment lowers asymmetric dimethylarginine concentrations in patients with type 2 diabetes
Metab. Clin. Exp.
2002
51: 843-846
|
| 19249171 |
Huo T et al.:
Metabonomic study of biochemical changes in the serum of type 2 diabetes mellitus patients after the treatment of metformin hydrochloride
J Pharm Biomed Anal
2009
49: 976-982
|
| 23900241 |
author information missing
article information missing
|
| 16443786 |
Davis BJ et al.:
Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase
Diabetes
2006
55: 496-505
|
| 22475684 |
Tornio A et al.:
Drug interactions with oral antidiabetic agents: pharmacokinetic mechanisms and clinical implications
Trends Pharmacol. Sci.
2012
33: 312-322
|
| 11797013 |
Minokoshi Y et al.:
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
Nature
2002
415: 339-343
|
| 18401339 |
Song IS et al.:
Genetic variants of the organic cation transporter 2 influence the disposition of metformin
Clin. Pharmacol. Ther.
2008
84: 559-562
|
| 17476361 |
Shu Y et al.:
Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action
J. Clin. Invest.
2007
117: 1422-1431
|
| 23043162 |
Floegel A et al.:
Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach
Diabetes
2013
62: 639-648
|
| 22834969 |
Yu Z et al.:
Human serum metabolic profiles are age dependent
Aging Cell
2012
11: 960-967
|
| 21852955 |
Mittelstrass K et al.:
Discovery of sexual dimorphisms in metabolic and genetic biomarkers
PLoS Genet.
2011
7
|
| 24816436 |
Altmaier E et al.:
Metabolomics approach reveals effects of antihypertensives and lipid-lowering drugs on the human metabolism
Eur. J. Epidemiol.
2014
29: 325-336
|
| 9655773 |
Millet L et al.:
Catecholamine effects on lipolysis and blood flow in human abdominal and femoral adipose tissue
J. Appl. Physiol.
1998
85: 181-188
|
| 10678541 |
Vanhees L et al.:
Effect of bisoprolol and atenolol on endurance exercise capacity in healthy men
J. Hypertens.
2000
18: 35-43
|
| 12208785 |
Tom B et al.:
Bradykinin potentiation by ACE inhibitors: a matter of metabolism
Br. J. Pharmacol.
2002
137: 276-284
|
| 12957664 |
Meaney S et al.:
On the origin of the cholestenoic acids in human circulation
Steroids
2003
68: 595-601
|
| 3183524 |
Kempen HJ et al.:
Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans
J. Lipid Res.
1988
29: 1149-1155
|
| 19309761 |
Cai S et al.:
Lysophosphatidylcholine--biomarker of Metformin action: studied using UPLC/MS/MS
Biomed. Chromatogr.
2009
23: 782-786
|
| 17130513 |
Guo Y et al.:
CHRM3 gene variation is associated with decreased acute insulin secretion and increased risk for early-onset type 2 diabetes in Pima Indians
Diabetes
2006
55: 3625-3629
|
| 24847880 |
Madiraju AK et al.:
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
Nature
2014
510: 542-546
|
| 10933890 |
Abbud W et al.:
Stimulation of AMP-activated protein kinase (AMPK) is associated with enhancement of Glut1-mediated glucose transport
Arch. Biochem. Biophys.
2000
380: 347-352
|
| 17095593 |
Chau-Van C et al.:
Metformin inhibits adenosine 5-monophosphate-activated kinase activation and prevents increases in neuropeptide Y expression in cultured hypothalamic neurons
Endocrinology
2007
148: 507-511
|
| 22950061 |
Lee CK et al.:
Intracerebroventricular injection of metformin induces anorexia in rats
Diabetes Metab J
2012
36: 293-299
|
| 16219720 |
Vigersky RA et al.:
Thyrotropin suppression by metformin
J. Clin. Endocrinol. Metab.
2006
91: 225-227
|
| 22640703 |
Boyda HN et al.:
Differential effects of 3 classes of antidiabetic drugs on olanzapine-induced glucose dysregulation and insulin resistance in female rats
J Psychiatry Neurosci
2012
37: 407-415
|
| 24667776 |
Hu Y et al.:
Metformin and berberine prevent olanzapine-induced weight gain in rats
PLoS ONE
2014
9
|
| 19385042 |
Jenkins RW et al.:
Roles and regulation of secretory and lysosomal acid sphingomyelinase
Cell. Signal.
2009
21: 836-846
|
| 15807880 |
Chubb SA et al.:
Prevalence and progression of subclinical hypothyroidism in women with type 2 diabetes: the Fremantle Diabetes Study
Clin. Endocrinol. (Oxf)
2005
62: 480-486
|
| 19502536 |
Cappelli C et al.:
TSH-lowering effect of metformin in type 2 diabetic patients: differences between euthyroid, untreated hypothyroid, and euthyroid on L-T4 therapy patients
Diabetes Care
2009
32: 1589-1590
|
| 24847884 |
Maianti JP et al.:
Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones
Nature
2014
511: 94-98
|
| 22629091 |
Kapadia KB et al.:
Association between altered thyroid state and insulin resistance
J Pharmacol Pharmacother
2012
3: 156-160
|
| 24995979 |
Kong X et al.:
IRF4 Is a Key Thermogenic Transcriptional Partner of PGC-1alpha
Cell
2014
158: 69-83
|
| 21762045 |
Reybier K et al.:
Insights into the redox cycle of human quinone reductase 2
Free Radic. Res.
2011
45: 1184-1195
|
| 24557852 |
Hussain T et al.:
Induction of CYP1A1, CYP1A2, CYP1B1, increased oxidative stress and inflammation in the lung and liver tissues of rats exposed to incense smoke
Mol. Cell. Biochem.
2014
391: 127-136
|
| 21308699 |
Alokail MS et al.:
Long-term exposure to incense smoke alters metabolism in Wistar albino rats
Cell Biochem. Funct.
2011
29: 96-101
|
| 16284649 |
Morino K et al.:
Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents
J. Clin. Invest.
2005
115: 3587-3593
|
| 23090186 |
Kim MY et al.:
Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1alpha axis in db/db mice
Diabetologia
2013
56: 204-217
|
| 18583386 |
Green RM et al.:
Reactive oxygen species from the uncoupling of human cytochrome P450 1B1 may contribute to the carcinogenicity of dioxin-like polychlorinated biphenyls
Mutagenesis
2008
23: 457-463
|
| 24968355 |
Hsieh TC et al.:
Biochemical and Cellular Evidence Demonstrating AKT-1 as a Binding Partner for Resveratrol Targeting Protein NQO2
PLoS ONE
2014
9
|
| 15350128 |
Buryanovskyy L et al.:
Crystal structure of quinone reductase 2 in complex with resveratrol
Biochemistry
2004
43
|
| 11154737 |
Long DJ 2nd et al.:
NRH:quinone oxidoreductase2 (NQO2)
Chem. Biol. Interact.
2000
129: 99-112
|
| 18347329 |
Arany Z et al.:
Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1alpha and oxidative phosphorylation
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 4721-4726
|
| 24275351 |
Kemper MF et al.:
Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection
Eur. J. Pharmacol.
2014
723: 322-329
|
| 23093066 |
Kemper MF et al.:
Endogenous ovarian hormones affect mitochondrial efficiency in cerebral endothelium via distinct regulation of PGC-1 isoforms
J. Cereb. Blood Flow Metab.
2013
33: 122-128
|
| 19773550 |
Zhang Y et al.:
Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1alpha
J. Biol. Chem.
2009
284
|
| 23093952 |
Jun HJ et al.:
Transcriptional Activity of PGC-1alpha and NT-PGC-1alpha Is Differentially Regulated by Twist-1 in Brown Fat Metabolism
PPAR Res
2012
2012
|
| 24400142 |
Ydfors M et al.:
The truncated splice variants, NT-PGC-1alpha and PGC-1alpha4, increase with both endurance and resistance exercise in human skeletal muscle
Physiol Rep
2013
1
|
| 24848065 |
Jun HJ et al.:
NT-PGC-1alpha activation attenuates high-fat diet-induced obesity by enhancing brown fat thermogenesis and adipose tissue oxidative metabolism
|
| 22469840 |
Choi EJ et al.:
Quercetin acts as an antioxidant and downregulates CYP1A1 and CYP1B1 against DMBA-induced oxidative stress in mice
Oncol. Rep.
2012
28: 291-296
|
| 18276086 |
Ramos AA et al.:
Antigenotoxic effects of quercetin, rutin and ursolic acid on HepG2 cells: evaluation by the comet assay
Toxicol. Lett.
2008
177: 66-73
|
| 17055439 |
St-Pierre J et al.:
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
Cell
2006
127: 397-408
|
| 20005308 |
Dominy JE Jr et al.:
Nutrient-dependent regulation of PGC-1alphas acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5
Biochim. Biophys. Acta
2010
1804: 1676-1683
|
| 20351112 |
Chang JS et al.:
Regulation of NT-PGC-1alpha subcellular localization and function by protein kinase A-dependent modulation of nuclear export by CRM1
J. Biol. Chem.
2010
285
|
| 22282499 |
Chang JS et al.:
NT-PGC-1alpha protein is sufficient to link beta3-adrenergic receptor activation to transcriptional and physiological components of adaptive thermogenesis
J. Biol. Chem.
2012
287: 9100-9111
|
| 15044633 |
Marchand A et al.:
Regulation of NAD(P)H:quinone oxidoreductase 1 gene expression by CYP1A1 activity
Mol. Pharmacol.
2004
65: 1029-1037
|
| 25136584 |
Wen X et al.:
Effect of Exercise Intensity on Isoform-Specific Expressions of NT-PGC-1 alpha mRNA in Mouse Skeletal Muscle
Biomed Res Int
2014
2014
|
| 22237023 |
Bostrom P et al. et al.:
A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Nature
2012
481: 463-468
|
| 24411942 |
Roberts LD et al.:
beta-Aminoisobutyric acid induces browning of white fat and hepatic beta-oxidation and is inversely correlated with cardiometabolic risk factors
Cell Metab.
2014
19: 96-108
|
| 18511502 |
Miura S et al.:
Isoform-specific increases in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to beta2-adrenergic receptor activation and exercise
Endocrinology
2008
149: 4527-4533
|
| 19233136 |
Yoshioka T et al.:
Identification and characterization of an alternative promoter of the human PGC-1alpha gene
Biochem. Biophys. Res. Commun.
2009
381: 537-543
|
| 21098736 |
Tadaishi M et al.:
Effect of exercise intensity and AICAR on isoform-specific expressions of murine skeletal muscle PGC-1alpha mRNA: a role of beta(2)-adrenergic receptor activation
Am. J. Physiol. Endocrinol. Metab.
2011
300: E341-E349
|
| 21757867 |
Johri A et al.:
Truncated peroxisome proliferator-activated receptor-gamma coactivator 1alpha splice variant is severely altered in Huntingtons disease
Neurodegener Dis
2011
8: 496-503
|
| 24907054 |
Popov DV et al.:
Exercise-induced expression of peroxisome proliferator-activated receptor gamma coactivator-1alpha isoforms in skeletal muscle of endurance-trained males
J Physiol Sci
2014
64: 317-323
|
| 22237023 |
Bostrom P et al.:
A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Nature
2012
481: 463-468
|
| 23505321 |
Kok BP et al.:
Differential regulation of the expressions of the PGC-1alpha splice variants, lipins, and PPARalpha in heart compared to liver
J. Lipid Res.
2013
54: 1662-1677
|
| 22315324 |
Santulli G et al.:
Age-related impairment in insulin release: the essential role of beta(2)-adrenergic receptor
Diabetes
2012
61: 692-701
|
| 19553684 |
Amat R et al.:
SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD
J. Biol. Chem.
2009
284
|
| 7626127 |
Stoffel M et al.:
Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male Zucker diabetic fatty rats
Biochem. Biophys. Res. Commun.
1995
212: 894-899
|
| 12764228 |
Handschin C et al.:
An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 7111-7116
|
| 17932564 |
Handschin C et al.:
Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk
J. Clin. Invest.
2007
117: 3463-3474
|
| 24505137 |
Thom R et al.:
Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by truncated peroxisome proliferator-activated receptor gamma coactivator (PGC)-1alpha
J. Biol. Chem.
2014
13: 8810-8817
|
| 23217713 |
Ruas JL et al.:
A PGC-1alpha isoform induced by resistance training regulates skeletal muscle hypertrophy
Cell
2012
151: 1319-1331
|
| 19918075 |
Wenz T et al.:
Increased muscle PGC-1alpha expression protects from sarcopenia and metabolic disease during aging
Proc. Natl. Acad. Sci. U.S.A.
2009
48
|
| 21368268 |
Xu X et al.:
Exercise ameliorates high-fat diet-induced metabolic and vascular dysfunction, and increases adipocyte progenitor cell population in brown adipose tissue
Am. J. Physiol. Regul. Integr. Comp. Physiol.
2011
300
|
| 24638054 |
Hatazawa Y et al.:
PGC-1alpha-mediated branched-chain amino acid metabolism in the skeletal muscle
PLoS ONE
2014
9
|
| 22174785 |
Tadaishi M et al.:
Skeletal muscle-specific expression of PGC-1alpha-b, an exercise-responsive isoform, increases exercise capacity and peak oxygen uptake
PLoS ONE
2011
6
|
| 19966219 |
Chinsomboon J et al.:
The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 12832613 |
Patti ME et al.:
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 8466-8471
|
| 15087503 |
Schreiber SN et al.:
The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis
Proc. Natl. Acad. Sci. U.S.A.
2004
101: 6472-6477
|
| 12578979 |
Czubryt MP et al.:
Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha ) and mitochondrial function by MEF2 and HDAC5
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 1711-1716
|
| 16122419 |
Handschin C et al.:
Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha
Cell
2005
122: 505-515
|
| 18288196 |
Arany Z et al.:
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha
Nature
2008
451: 1008-1012
|
| 24383721 |
Weydt P et al.:
A single nucleotide polymorphism in the coding region of PGC-1alpha is a male-specific modifier of Huntington disease age-at-onset in a large European cohort
BMC Neurol
2014
14: 1
|
| 23021218 |
Ye L et al.:
TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis
Cell
2012
151: 96-110
|
| 24611020 |
Mackenzie RW et al.:
Akt/PKB activation and insulin signaling: a novel insulin signaling pathway in the treatment of type 2 diabetes
Diabetes Metab Syndr Obes
2014
7: 55-64
|
| 9792713 |
VanRenterghem B et al.:
Interaction of insulin receptor substrate-1 with the sigma3A subunit of the adaptor protein complex-3 in cultured adipocytes
J. Biol. Chem.
1998
273
|
| 20512086 |
Zhou JB et al.:
Variants in KCNQ1, AP3S1, MAN2A1, and ALDH7A1 and the risk of type 2 diabetes in the Chinese Northern Han population: a case-control study and meta-analysis
Med. Sci. Monit.
2010
16: BR179-BR183
|
| 19897600 |
Gleason CE et al.:
Role of insulin-like growth factor-binding protein 5 (IGFBP5) in organismal and pancreatic beta-cell growth
Mol. Endocrinol.
2010
24: 178-192
|
| 22617471 |
Leto D et al.:
Regulation of glucose transport by insulin: traffic control of GLUT4
Nat. Rev. Mol. Cell Biol.
2012
13: 383-396
|
| 20719858 |
Zhang Y et al.:
Fructose-1,6-bisphosphatase regulates glucose-stimulated insulin secretion of mouse pancreatic beta-cells
Endocrinology
2010
151: 4688-4695
|
| 23155694 |
Wojcik M et al.:
The association of FGF23 levels in obese adolescents with insulin sensitivity
J. Pediatr. Endocrinol. Metab.
2012
25: 687-690
|
| 19324482 |
Marsenic O et al.:
Glucose control by the kidney: an emerging target in diabetes
Am. J. Kidney Dis.
2009
53: 875-883
|
| 14563825 |
Jove M et al.:
Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone
J. Lipid Res.
2004
45: 113-123
|
| 17310221 |
Mensink M et al.:
Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1 alpha and PPAR beta/delta gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus
Int J Obes (Lond)
2007
31: 1302-1310
|
| 19003958 |
Bosch MA et al.:
17Beta-estradiol regulation of the mRNA expression of T-type calcium channel subunits: role of estrogen receptor alpha and estrogen receptor beta
J. Comp. Neurol.
2009
512: 347-358
|
| 11555828 |
Badawi AF et al.:
Role of human cytochrome P450 1A1, 1A2, 1B1, and 3A4 in the 2-, 4-, and 16alpha-hydroxylation of 17beta-estradiol
Metab. Clin. Exp.
2001
50: 1001-1003
|
| 19003958 |
Bosch MA et al.:
17Beta-estradiol regulation of the mRNA expression of T-type calcium channel subunits: role of estrogen receptor alpha and estrogen receptor beta
J. Comp. Neurol.
2009
3: 347-358
|
| 22539796 |
Kwon JH et al.:
Regulation of cytosolic phospholipase A2 phosphorylation by proteolytic cleavage of annexin A1 in activated mast cells
J. Immunol.
2012
188: 5665-5673
|
| 23203005 |
Han X et al.:
Evaluation of variant A45T in NEUROD1/BETA2 for its association with type 2 diabetes mellitus
Endocrine
2013
44: 99-106
|
| 9702684 |
Takiyama Y et al.:
A Japanese family with spinocerebellar ataxia type 6 which includes three individuals homozygous for an expanded CAG repeat in the SCA6/CACNL1A4 gene
J. Neurol. Sci.
1998
158: 141-147
|
| 24801871 |
Lungkaphin A et al.:
Impaired insulin signaling affects renal organic anion transporter 3 (Oat3) function in streptozotocin-induced diabetic rats
PLoS One
2014
9
|
| 23826284 |
Zheng JS et al.:
Polyunsaturated Fatty Acids Modulate the Association between Genetic Variants and Insulin Resistance
PLoS ONE
2013
8
|
| 17934712 |
Holmkvist J et al.:
Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion
Diabetologia
2007
50: 2467-2475
|
| 23516528 |
Dixit SS et al.:
Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance
PLoS ONE
2013
8
|
| 25017062 |
Sato M et al.:
The role of the endocrine system in feeding-induced tissue-specific circadian entrainment
Cell Rep
2014
8: 393-401
|
| 8093061 |
Melki V et al.:
Annexin I as a potential inhibitor of insulin receptor protein tyrosine kinase
Biochem. Biophys. Res. Commun.
1994
203: 813-819
|
| 10807665 |
Croxtall JD et al.:
Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanism
Br. J. Pharmacol.
2000
130: 289-298
|
| 24312665 |
Akasheh RT et al.:
Increased adiposity in annexin A1-deficient mice
PLoS ONE
2013
8
|
| 20578244 |
Bizzarro V et al.:
Role of Annexin A1 in mouse myoblast cell differentiation
J. Cell. Physiol.
2010
224: 757-765
|
| 21106753 |
Rasbach KA et al.:
PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 20418374 |
Rangwala SM et al.:
Estrogen-related receptor gamma is a key regulator of muscle mitochondrial activity and oxidative capacity
J. Biol. Chem.
2010
285
|
| 18004065 |
Lin CL et al.:
Simvastatin reverses high glucose-induced apoptosis of mesangial cells via modulation of Wnt signaling pathway
Am. J. Nephrol.
2008
28: 290-297
|
| 24646999 |
Smemo S et al.:
Obesity-associated variants within FTO form long-range functional connections with IRX3
Nature
2014
507: 371-375
|
| 17658951 |
Scuteri A et al.:
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
PLoS Genet.
2007
3: E115
|
| 24673193 |
Coto-Segura P et al.:
Effect of the FTO rs9930506 polymorphism on obesity and the main clinical outcomes in patients with psoriasis
Br. J. Dermatol.
2014
171: 917-919
|
| 17021763 |
Sommer DM et al.:
Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis
Arch. Dermatol. Res.
2006
298: 321-328
|
| 17852416 |
Foo C et al.:
Downregulation of beta-catenin and transdifferentiation of human osteoblasts to adipocytes under estrogen deficiency
Gynecol. Endocrinol.
2007
23: 535-540
|
| 23619963 |
Sibilia V et al.:
Dietary tryptophan manipulation reveals a central role for serotonin in the anabolic response of appendicular skeleton to physical activity in rats
Endocrine
2013
44: 790-802
|
| 22058016 |
Qiao LJ et al.:
Simvastatin promotes osteogenic differentiation of mouse embryonic stem cells via canonical Wnt/beta-catenin signaling
Mol. Cells
2011
32: 437-444
|
| 24510055 |
Jiang Y et al.:
Pravastatin prevents steroid-induced osteonecrosis in rats by suppressing PPARgamma expression and activating Wnt signaling pathway
Exp. Biol. Med. (Maywood)
2014
239: 347-355
|
| 19041748 |
Yadav VK et al.:
Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum
Cell
2008
135: 825-837
|
| 19673927 |
Saarinen A et al.:
Low density lipoprotein receptor-related protein 5 (LRP5) mutations and osteoporosis, impaired glucose metabolism and hypercholesterolaemia
Clin. Endocrinol. (Oxf)
2010
72: 481-488
|
| 23447675 |
Solito R et al.:
Mitochondrial aldehyde dehydrogenase-2 activation prevents beta-amyloid-induced endothelial cell dysfunction and restores angiogenesis
J. Cell. Sci.
2013
126: 1952-1961
|
| 23066786 |
Liu Q et al.:
Nitrosative stress plays an important role in Wnt pathway activation in diabetic retinopathy
Antioxid. Redox Signal.
2013
18: 1141-1153
|
| 20978740 |
Zhou T et al.:
The role of lipid peroxidation products and oxidative stress in activation of the canonical wingless-type MMTV integration site (WNT) pathway in a rat model of diabetic retinopathy
Diabetologia
2011
54: 459-468
|
| 25089371 |
Almario RU et al.:
Roles of Circulating WNT-Signaling Proteins and WNT-Inhibitors in Human Adiposity, Insulin Resistance, Insulin Secretion, and Inflammation
|
| 22036861 |
You L et al.:
High cholesterol diet increases osteoporosis risk via inhibiting bone formation in rats
Acta Pharmacol. Sin.
2011
32: 1498-1504
|
| 12509515 |
Fujino T et al.:
Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 229-234
|
| 17994217 |
Schinner S et al.:
Regulation of insulin secretion, glucokinase gene transcription and beta cell proliferation by adipocyte-derived Wnt signalling molecules
Diabetologia
2008
51: 147-154
|
| 19165345 |
Lee SH et al.:
Islet specific Wnt activation in human type II diabetes
Exp Diabetes Res
2008
2008
|
| 24006088 |
Rebuffat SA et al.:
Downregulation of Sfrp5 promotes beta cell proliferation during obesity in the rat
Diabetologia
2013
56: 2446-2455
|
| 23650507 |
Rohatgi N et al.:
Novel insulin sensitizer modulates nutrient sensing pathways and maintains beta-cell phenotype in human islets
PLoS ONE
2013
8
|
| 16344552 |
Kwon G et al.:
Glucose-stimulated DNA synthesis through mammalian target of rapamycin (mTOR) is regulated by KATP channels: effects on cell cycle progression in rodent islets
J. Biol. Chem.
2006
281: 3261-3267
|
| 22461615 |
Lamming DW et al.:
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity
Science
2012
6076: 1638-1643
|
| 24439111 |
Kulzer JR et al.:
A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell
Am. J. Hum. Genet.
2014
94: 186-197
|
| 10567552 |
Smith SB et al.:
Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development
Mol. Cell. Biol.
1999
19: 8272-8280
|
| 1642362 |
et al.:
Fewer failed spinal anesthetics with the Sprotte needle
Anesthesiology
1992
77: 393
|
| 22521316 |
Kooptiwut S et al.:
Defective PAX4 R192H transcriptional repressor activities associated with maturity onset diabetes of the young and early onset-age of type 2 diabetes
J. Diabetes Complicat.
2012
26: 343-347
|
| 23532257 |
Ma RC et al.:
Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4
Diabetologia
2013
56: 1291-1305
|
| 17989064 |
Brun T et al.:
The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1
Hum. Mol. Genet.
2008
17: 478-489
|
| 11723072 |
Shimajiri Y et al.:
A missense mutation of Pax4 gene (R121W) is associated with type 2 diabetes in Japanese
Diabetes
2001
50: 2864-2869
|
| 15509590 |
Mauvais-Jarvis F et al.:
PAX4 gene variations predispose to ketosis-prone diabetes
Hum. Mol. Genet.
2004
13: 3151-3159
|
| 19760265 |
Torsvik J et al.:
Mutations in the VNTR of the carboxyl-ester lipase gene (CEL) are a rare cause of monogenic diabetes
Hum. Genet.
2010
127: 55-64
|
| 16369531 |
Raeder H et al. et al.:
Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction
Nat Genet
2006
38: 54-62
|
| 23770712 |
Tjora E et al.:
Severe pancreatic dysfunction but compensated nutritional status in monogenic pancreatic disease caused by carboxyl-ester lipase mutations
Pancreas
2013
42: 1078-1084
|
| 24062244 |
Raeder H et al. et al.:
Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid
Diabetes
2014
63: 259-269
|
| 17259390 |
Raeder H et al.:
Pancreatic lipomatosis is a structural marker in nondiabetic children with mutations in carboxyl-ester lipase
Diabetes
2007
56: 444-449
|
| 11514232 |
Lombardo D et al.:
Bile salt-dependent lipase: its pathophysiological implications
Biochim Biophys Acta
2001
1533: 1-28
|
| 25369532 |
Bjorlykke Y et al.:
Carboxyl-ester lipase maturity-onset diabetes of the young disease protein biomarkers in secretin-stimulated duodenal juice
J Proteome Res
2015
14: 521-530
|
| 25160620 |
Torsvik J et al.:
Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction
J Biol Chem
2014
289
|
| 25016691 |
et al.:
Metformin suppresses lipid accumulation in skeletal muscle by promoting fatty acid oxidation
Clin Lab
2014
60: 887-896
|
| 23589285 |
Lomberk G et al.:
Kruppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young
J Biol Chem
2013
288
|
| 15531587 |
Cao S et al.:
KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling
J Biol Chem
2005
280: 1901-1910
|
| 22628545 |
Grunewald M et al. et al.:
Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein pathway in stress-induced monoamine oxidase A expression
J Biol Chem
2012
287
|
| 20709022 |
Yamamoto K et al.:
Transcriptional regulation of a brown adipocyte-specific gene, UCP1, by KLF11 and KLF15
Biochem Biophys Res Commun
2010
400: 175-180
|
| 24586865 |
Zhang H et al.:
Involvement of KLF11 in hepatic glucose metabolism in mice via suppressing of PEPCK-C expression
PLoS One
2014
9
|
| 23183531 |
Zhang H et al. et al.:
Mouse KLF11 regulates hepatic lipid metabolism
J Hepatol
2013
58: 763-770
|
| 23042817 |
Fan Y et al.:
Kruppel-like factor-11, a transcription factor involved in diabetes mellitus, suppresses endothelial cell activation via the nuclear factor-kappaB signaling pathway
Arterioscler Thromb Vasc Biol
2012
32: 2981-2988
|
| 15592940 |
Kavvoura FK et al.:
Ala45Thr polymorphism of the NEUROD1 gene and diabetes susceptibility: a meta-analysis
Hum Genet
2005
116: 192-199
|
| 11719843 |
Kristinsson SY et al.:
MODY in Iceland is associated with mutations in HNF-1alpha and a novel mutation in NeuroD1
Diabetologia
2001
44: 2098-2103
|
| 17440689 |
Liu L et al.:
A novel mutation, Ser159Pro in the NeuroD1/BETA2 gene contributes to the development of diabetes in a Chinese potential MODY family
Mol. Cell. Biochem.
2007
303: 115-120
|
| 18191635 |
Kim HS et al.:
Rosiglitazone stimulates the release and synthesis of insulin by enhancing GLUT-2, glucokinase and BETA2/NeuroD expression
Biochem Biophys Res Commun
2008
367: 623-629
|
| 18331410 |
Gonsorcikova L et al.:
Autosomal inheritance of diabetes in two families characterized by obesity and a novel H241Q mutation in NEUROD1
Pediatr Diabetes
2008
9: 367-372
|
| 20573748 |
Rubio-Cabezas O et al.:
Homozygous mutations in NEUROD1 are responsible for a novel syndrome of permanent neonatal diabetes and neurological abnormalities
Diabetes
2010
59: 2326-2331
|
| 25441779 |
Kanthimathi S et al.:
Identification and molecular characterization of HNF1B gene mutations in Indian diabetic patients with renal abnormalities
Ann. Hum. Genet.
2015
79: 10-19
|
| 20378641 |
Heidet L et al.:
Spectrum of HNF1B mutations in a large cohort of patients who harbor renal diseases
Clin J Am Soc Nephrol
2010
5: 1079-1090
|
| 19389850 |
Adalat S et al.:
HNF1B mutations associate with hypomagnesemia and renal magnesium wasting
J. Am. Soc. Nephrol.
2009
20: 1123-1131
|
| 15068978 |
Bellanne-Chantelot C et al.:
Clinical spectrum associated with hepatocyte nuclear factor-1beta mutations
Ann. Intern. Med.
2004
140: 510-517
|
| 15029248 |
Gresh L et al.:
A transcriptional network in polycystic kidney disease
EMBO J.
2004
23: 1657-1668
|
| 23926411 |
Jo W et al.:
A Case of Novel Mutation of HNF1B in Maturity-onset Diabetes of the Young Type 5 (MODY5)
Clin Pediatr Endocrinol
2012
21: 53-55
|
| 21767339 |
Gonc EN et al.:
HNF1B mutation in a Turkish child with renal and exocrine pancreas insufficiency, diabetes and liver disease
Pediatr Diabetes
2012
13: E1-E5
|
| 15930087 |
et al.:
Mutations in hepatocyte nuclear factor-1beta and their related phenotypes
J. Med. Genet.
2006
43: 84-90
|
| 22587559 |
Edghill EL et al.:
HNF1B deletions in patients with young-onset diabetes but no known renal disease
Diabet. Med.
2013
30: 114-117
|
| 11562418 |
Kolatsi-Joannou M et al.:
Hepatocyte nuclear factor-1beta: a new kindred with renal cysts and diabetes and gene expression in normal human development
J. Am. Soc. Nephrol.
2001
12: 2175-2180
|
| 9703339 |
Nishigori H et al.:
Frameshift mutation, A263fsinsGG, in the hepatocyte nuclear factor-1beta gene associated with diabetes and renal dysfunction
Diabetes
1998
47: 1354-1355
|
| 12161522 |
Furuta H et al.:
Nonsense and missense mutations in the human hepatocyte nuclear factor-1 beta gene (TCF2) and their relation to type 2 diabetes in Japanese
J. Clin. Endocrinol. Metab.
2002
87: 3859-3863
|
| 12148114 |
Montoli A et al.:
Renal cysts and diabetes syndrome linked to mutations of the hepatocyte nuclear factor-1 beta gene: description of a new family with associated liver involvement
Am. J. Kidney Dis.
2002
40: 397-402
|
| 11918730 |
Bingham C et al.:
Solitary functioning kidney and diverse genital tract malformations associated with hepatocyte nuclear factor-1beta mutations
Kidney Int.
2002
61: 1243-1251
|
| 11845237 |
et al.:
A novel hepatocyte nuclear factor-1beta (MODY-5) gene mutation in an Italian family with renal dysfunctions and early-onset diabetes
Diabetologia
2002
45: 153-154
|
| 11317673 |
et al.:
Splice site mutation in the hepatocyte nuclear factor-1 beta gene, IVS2nt + 1G > A, associated with maturity-onset diabetes of the young, renal dysplasia and bicornuate uterus
Diabetologia
2001
44: 387-388
|
| 12675839 |
Bingham C et al.:
Atypical familial juvenile hyperuricemic nephropathy associated with a hepatocyte nuclear factor-1beta gene mutation
Kidney Int.
2003
63: 1645-1651
|
| 15001636 |
Kitanaka S et al.:
Promoter-specific repression of hepatocyte nuclear factor (HNF)-1 beta and HNF-1 alpha transcriptional activity by an HNF-1 beta missense mutant associated with Type 5 maturity-onset diabetes of the young with hepatic and biliary manifestations
J. Clin. Endocrinol. Metab.
2004
89: 1369-1378
|
| 25246411 |
Fournier JP et al.:
Metformin and low levels of thyroid-stimulating hormone in patients with type 2 diabetes mellitus
CMAJ
2014
186: 1138-1145
|
| 25100149 |
Furukawa S et al.:
Association between subclinical hypothyroidism and diabetic nephropathy in patients with type 2 diabetes mellitus
Endocr. J.
2014
61: 1011-1018
|
| 25144761 |
Jonatan D et al.:
Sox17 regulates insulin secretion in the normal and pathologic mouse beta cell
PLoS One
2014
9
|
| 21829703 |
Dubois CL et al.:
Sox9-haploinsufficiency causes glucose intolerance in mice
PLoS ONE
2011
6
|
| 20621032 |
Fajans SS et al.:
Obesity and hyperinsulinemia in a family with pancreatic agenesis and MODY caused by the IPF1 mutation Pro63fsX60
Transl Res
2010
156: 7-14
|
| 15121856 |
Liu A et al.:
Identification of PCIF1, a POZ domain protein that inhibits PDX-1 (MODY4) transcriptional activity
Mol. Cell. Biol.
2004
24: 4372-4383
|
| 20009086 |
Nicolino M et al.:
A novel hypomorphic PDX1 mutation responsible for permanent neonatal diabetes with subclinical exocrine deficiency
Diabetes
2010
59: 733-740
|
| 8988180 |
Stoffers DA et al.:
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
Nat. Genet.
1997
15: 106-110
|
| 11078452 |
Clocquet AR et al.:
Impaired insulin secretion and increased insulin sensitivity in familial maturity-onset diabetes of the young 4 (insulin promoter factor 1 gene)
Diabetes
2000
49: 1856-1864
|
| 12970316 |
Schwitzgebel VM et al.:
Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1
J. Clin. Endocrinol. Metab.
2003
88: 4398-4406
|
| 19496967 |
Thomas IH et al.:
Neonatal diabetes mellitus with pancreatic agenesis in an infant with homozygous IPF-1 Pro63fsX60 mutation
Pediatr Diabetes
2009
10: 492-496
|
| 10545531 |
Hani EH et al.:
Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus
J. Clin. Invest.
1999
104: R41-R48
|
| 10545530 |
Macfarlane WM et al.:
Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes
J. Clin. Invest.
1999
104: R33-R39
|
| 25628604 |
Arcidiacono B et al.:
Cooperation between HMGA1, PDX-1, and MafA is Essential for Glucose-Induced Insulin Transcription in Pancreatic Beta Cells
Front Endocrinol (Lausanne)
2015
5: 237
|
| 23274887 |
Valtat B et al.:
Fetal PGC-1alpha overexpression programs adult pancreatic beta-cell dysfunction
Diabetes
2013
62: 1206-1216
|
| 19817786 |
Fujimoto K et al.:
Pdx1 and other factors that regulate pancreatic beta-cell survival
Diabetes Obes Metab
2009
11: Suppl 4 30-37
|
| 14764823 |
Cockburn BN et al.:
Insulin promoter factor-1 mutations and diabetes in Trinidad: identification of a novel diabetes-associated mutation (E224K) in an Indo-Trinidadian family
J. Clin. Endocrinol. Metab.
2004
89: 971-978
|
| 9097962 |
Vaxillaire M et al.:
Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young (MODY3)
Hum. Mol. Genet.
1997
6: 583-586
|
| 11162430 |
Bjorkhaug L et al.:
MODY associated with two novel hepatocyte nuclear factor-1alpha loss-of-function mutations (P112L and Q466X)
Biochem. Biophys. Res. Commun.
2000
279: 792-798
|
| 12574234 |
Bjorkhaug L et al.:
Hepatocyte nuclear factor-1 alpha gene mutations and diabetes in Norway
J. Clin. Endocrinol. Metab.
2003
88: 920-931
|
| 9562352 |
Isomaa B et al.:
Chronic diabetic complications in patients with MODY3 diabetes
Diabetologia
1998
41: 467-473
|
| 25697093 |
Rutter GA et al.:
Pancreatic beta-cell identity, glucose sensing and the control of insulin secretion
Biochem. J.
2015
466: 203-218
|
| 23040067 |
Moran I et al.:
Human beta cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes
Cell Metab.
2012
16: 435-448
|
| 16715098 |
Senee V et al.:
Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism
Nat. Genet.
2006
38: 682-687
|
| 24149837 |
Locke JM et al.:
Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion
Diabetologia
2014
57: 122-128
|
| 22983607 |
Shojima N et al. et al.:
Depletion of homeodomain-interacting protein kinase 3 impairs insulin secretion and glucose tolerance in mice
Diabetologia
2012
55: 3318-3330
|
| 11781323 |
Brissova M et al.:
Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion
J. Biol. Chem.
2002
277
|
| 17659992 |
Babu DA et al.:
A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis
Mol. Genet. Metab.
2007
92: 43-55
|
| 22808921 |
Bacon S et al.:
Serum levels of pancreatic stone protein (PSP)/reg1A as an indicator of beta-cell apoptosis suggest an increased apoptosis rate in hepatocyte nuclear factor 1 alpha (HNF1A-MODY) carriers from the third decade of life onward
BMC Endocr Disord
2012
12: 13
|
| 20682686 |
Bonner C et al.:
INS-1 cells undergoing caspase-dependent apoptosis enhance the regenerative capacity of neighboring cells
Diabetes
2010
59: 2799-2808
|
| 23803251 |
Kyithar MP et al.:
Effects of hepatocyte nuclear factor-1A and -4A on pancreatic stone protein/regenerating protein and C-reactive protein gene expression: implications for maturity-onset diabetes of the young
J Transl Med
2013
11: 156
|
| 11724785 |
Wobser H et al.:
Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death
J. Biol. Chem.
2002
277: 6413-6421
|
| 8866553 |
Byrne MM et al.:
Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12
Diabetes
1996
45: 1503-1510
|
| 12031966 |
Yang Q et al.:
Hepatocyte nuclear factor-1alpha modulates pancreatic beta-cell growth by regulating the expression of insulin-like growth factor-1 in INS-1 cells
Diabetes
2002
51: 1785-1792
|
| 10944108 |
Wang H et al.:
Molecular targets of a human HNF1 alpha mutation responsible for pancreatic beta-cell dysfunction
EMBO J.
2000
19: 4257-4264
|
| 21628466 |
Bonner C et al.:
Bone morphogenetic protein 3 controls insulin gene expression and is down-regulated in INS-1 cells inducibly expressing a hepatocyte nuclear factor 1A-maturity-onset diabetes of the young mutation
J. Biol. Chem.
2011
286
|
| 15543146 |
Sellick GS et al.:
Mutations in PTF1A cause pancreatic and cerebellar agenesis
Nat. Genet.
2004
36: 1301-1305
|
| 21749365 |
author information missing
A novel PTF1A mutation in a patient with severe pancreatic and cerebellar involvement
Clin. Genet.
2011
80: 196-198
|
| 19650412 |
Tutak E et al.:
A Turkish newborn infant with cerebellar agenesis/neonatal diabetes mellitus and PTF1A mutation
Genet. Couns.
2009
20: 147-152
|
| 25355311 |
Hanoun N et al.:
The E3 ubiquitin ligase thyroid hormone receptor-interacting protein 12 targets pancreas transcription factor 1a for proteasomal degradation
J. Biol. Chem.
2014
289
|
| 12185368 |
Kawaguchi Y et al.:
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
Nat. Genet.
2002
32: 128-134
|
| 9851981 |
Krapp A et al.:
The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas
Genes Dev.
1998
12: 3752-3763
|
| 16354684 |
Beres TM et al.:
PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L
Mol. Cell. Biol.
2006
26: 117-130
|
| 21852532 |
Holmstrom SR et al.:
LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function
Genes Dev.
2011
25: 1674-1679
|
| 17938243 |
Masui T et al.:
Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex
Genes Dev.
2007
21: 2629-2643
|
| 24733890 |
Millen KJ et al.:
Transformation of the cerebellum into more ventral brainstem fates causes cerebellar agenesis in the absence of Ptf1a function
Proc. Natl. Acad. Sci. U.S.A.
2014
111
|
| 1974112 |
Hesselschwerdt HJ et al.:
[Metabolic diseases of bones. Catamnestic study of the incidence and kind of problems in surgical treatment]
Aktuelle Traumatol
1990
20: 136-143
|
| 20627083 |
Schaffer AE et al.:
Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors
Dev. Cell
2010
18: 1022-1029
|
| 25374274 |
Gerdes JM et al.:
Ciliary dysfunction impairs beta-cell insulin secretion and promotes development of type 2 diabetes in rodents
Nat Commun
2014
5: 5308
|
| 21969560 |
Landsman L et al.:
Elevated Hedgehog/Gli signaling causes beta-cell dedifferentiation in mice
Proc. Natl. Acad. Sci. U.S.A.
2011
108
|
| 25504142 |
Williams CL et al.:
Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia
Nat Commun
2014
5: 5813
|
| 18317593 |
Rahmouni K et al.:
Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome
J. Clin. Invest.
2008
118: 1458-1467
|
| 22228099 |
Zhang Q et al.:
BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes
Hum. Mol. Genet.
2012
21: 1945-1953
|
| 25693948 |
Dalbay MT et al.:
Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF-1r Onto the Primary Cilium Associated With Cilia Elongation
Stem Cells
2015
33: 1952-1961
|
| 24862854 |
Teperino R et al.:
Canonical and non-canonical Hedgehog signalling and the control of metabolism
Semin. Cell Dev. Biol.
2014
33: 81-92
|
| 20972424 |
Boehlke C et al.:
Primary cilia regulate mTORC1 activity and cell size through Lkb1
Nat. Cell Biol.
2010
11: 1115-1122
|
| 18084282 |
Corbit KC et al.:
Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms
Nat. Cell Biol.
2008
10: 70-76
|
| 19808022 |
Granot Z et al.:
LKB1 regulates pancreatic beta cell size, polarity, and function
Cell Metab.
2009
10: 296-308
|
| 10614660 |
Maekawa F et al.:
Localization of glucokinase-like immunoreactivity in the rat lower brain stem: for possible location of brain glucose-sensing mechanisms
Endocrinology
2000
141: 375-384
|
| 15580285 |
Zhang Q et al.:
Disruption of IFT results in both exocrine and endocrine abnormalities in the pancreas of Tg737(orpk) mutant mice
Lab. Invest.
2005
85: 45-64
|
| 25830091 |
Sun G et al.:
LKB1 and AMPKalpha1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia
Mol Metab
2015
4: 277-286
|
| 11336458 |
Barton JC et al.:
Diagnosis of hemochromatosis in family members of probands: a comparison of phenotyping and HFE genotyping
Genet. Med.
1999
1: 89-93
|
| 8696333 |
Feder JN et al.:
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
Nat. Genet.
1996
13: 399-408
|
| 9162021 |
Feder JN et al.:
The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression
J. Biol. Chem.
1997
272
|
| 9356458 |
Waheed A et al.:
Hereditary hemochromatosis: effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells
Proc. Natl. Acad. Sci. U.S.A.
1997
94
|
| 19058322 |
author information missing
Function of the hemochromatosis protein HFE: Lessons from animal models
World J. Gastroenterol.
2008
14: 6893-6901
|
| 9439654 |
Mura C et al.:
Phenotype-genotype correlation in haemochromatosis subjects
Hum. Genet.
1997
101: 271-276
|
| 11812557 |
Beutler E et al.:
Penetrance of 845G--> A (C282Y) HFE hereditary haemochromatosis mutation in the USA
Lancet
2002
359: 211-218
|
| 14729817 |
Livesey KJ et al.:
The 16189 variant of mitochondrial DNA occurs more frequently in C282Y homozygotes with haemochromatosis than those without iron loading
J. Med. Genet.
2004
41: 6-10
|
| 10401000 |
de Villiers JN et al.:
Spectrum of mutations in the HFE gene implicated in haemochromatosis and porphyria
Hum. Mol. Genet.
1999
8: 1517-1522
|
| 25654085 |
Evangelista AS et al.:
HFE genotyping in patients with elevated serum iron indices and liver diseases
Biomed Res Int
2015
2015
|
| 25976471 |
Radio FC et al.:
Hereditary hemochromatosis type 1 phenotype modifiers in Italian patients. The controversial role of variants in HAMP, BMP2, FTL and SLC40A1 genes
Blood Cells Mol. Dis.
2015
55: 71-75
|
| 24068123 |
Vieira FM et al.:
Precipitating factors of porphyria cutanea tarda in Brazil with emphasis on hemochromatosis gene (HFE) mutations. Study of 60 patients
An Bras Dermatol
2013
88: 530-540
|
| 14647275 |
Papanikolaou G et al.:
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
Nat. Genet.
2004
36: 77-82
|
| 14982867 |
Lee PL et al.:
Genetic abnormalities and juvenile hemochromatosis: mutations of the HJV gene encoding hemojuvelin
Blood
2004
103: 4669-4671
|
| 15611318 |
author information missing
Homozygosity for a novel nonsense mutation (G66X) of the HJV gene causes severe juvenile hemochromatosis with fatal cardiomyopathy
Blood
2005
105: 432
|
| 24167545 |
Juanola-Falgarona M et al.:
Association between serum ferritin and osteocalcin as a potential mechanism explaining the iron-induced insulin resistance
PLoS ONE
2013
8
|
| 16604073 |
Babitt JL et al.:
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
Nat. Genet.
2006
38: 531-539
|
| 15997423 |
Angelopoulos NG et al.:
Osteoporosis in HFE2 juvenile hemochromatosis. A case report and review of the literature
Osteoporos Int
2006
17: 150-155
|
| 19796184 |
author information missing
Juvenile hemochromatosis due to homozygosity for the G320V mutation in the HJV gene with fatal outcome
Clin. Genet.
2009
76: 493-495
|
| 26070664 |
Schaefer A et al.:
The Epoxyeicosatrienoic Acid Pathway Enhances Hepatic Insulin Signaling and Is Repressed in Insulin-Resistant Mouse Liver
|
| 20234129 |
Varkonyi J et al.:
Hemochromatosis and hemojuvelin G320V homozygosity in a Hungarian woman
Acta Haematol.
2010
123: 191-193
|
| 18492090 |
Murugan RC et al.:
Early age-of-onset iron overload and homozygosity for the novel hemojuvelin mutation HJV R54X (exon 3; c.160A-->T) in an African American male of West Indies descent
Clin. Genet.
2008
74: 88-92
|
| 17768121 |
author information missing
Phenotypic and functional data confirm causality of the recently identified hemojuvelin p.r176c missense mutation
Haematologica
2007
92: 1262-1263
|
| 17339196 |
author information missing
Juvenile hemochromatosis caused by a novel combination of hemojuvelin G320V/R176C mutations in a 5-year old girl
Haematologica
2007
92: 421-422
|
| 22998440 |
Salama MF et al.:
Tumour necrosis factor alpha downregulates human hemojuvelin expression via a novel response element within its promoter
J. Biomed. Sci.
2012
19: 83
|
| 21873547 |
Nai A et al.:
TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals
Blood
2011
118: 4459-4462
|
| 21311510 |
Luciani N et al.:
Hemojuvelin: a new link between obesity and iron homeostasis
Obesity (Silver Spring)
2011
19: 1545-1551
|
| 20937842 |
Maxson JE et al.:
Matriptase-2- and proprotein convertase-cleaved forms of hemojuvelin have different roles in the down-regulation of hepcidin expression
J. Biol. Chem.
2010
285
|
| 24682660 |
Creighton Mitchell T et al.:
Diabetes and hemochromatosis
Curr. Diab. Rep.
2014
14: 488
|
| 15514116 |
Nemeth E et al.:
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
Science
2004
306: 2090-2093
|
| 15684062 |
Lee P et al.:
Regulation of hepcidin transcription by interleukin-1 and interleukin-6
Proc. Natl. Acad. Sci. U.S.A.
2005
102: 1906-1910
|
| 18451267 |
Du X et al.:
The serine protease TMPRSS6 is required to sense iron deficiency
Science
2008
320: 1088-1092
|
| 17593032 |
Weizer-Stern O et al.:
Hepcidin, a key regulator of iron metabolism, is transcriptionally activated by p53
Br. J. Haematol.
2007
138: 253-262
|
| 19252486 |
Andriopoulos B Jr et al.:
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
Nat. Genet.
2009
41: 482-487
|
| 15099344 |
Delatycki MB et al.:
A homozygous HAMP mutation in a multiply consanguineous family with pseudo-dominant juvenile hemochromatosis
Clin. Genet.
2004
65: 378-383
|
| 22297252 |
Hattori A et al.:
Identification of a novel mutation in the HAMP gene that causes non-detectable hepcidin molecules in a Japanese male patient with juvenile hemochromatosis
Blood Cells Mol. Dis.
2012
48: 179-182
|
| 10802645 |
Camaschella C et al.:
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22
Nat. Genet.
2000
25: 14-15
|
| 11313241 |
Roetto A et al.:
New mutations inactivating transferrin receptor 2 in hemochromatosis type 3
Blood
2001
97: 2555-2560
|
| 11984516 |
Girelli D et al.:
Clinical and pathologic findings in hemochromatosis type 3 due to a novel mutation in transferrin receptor 2 gene
Gastroenterology
2002
122: 1295-1302
|
| 19549277 |
et al.:
Natural history of TFR2-related hereditary hemochromatosis in a 47-yr-old Italian patient
Eur. J. Haematol.
2009
83: 494-496
|
| 18245657 |
author information missing
New TFR2 mutations in young Italian patients with hemochromatosis
Haematologica
2008
93: 309-310
|
| 16923517 |
Majore S et al.:
Homozygous p.M172K mutation of the TFR2 gene in an Italian family with type 3 hereditary hemochromatosis and early onset iron overload
Haematologica
2006
91: ECR33
|
| 18450729 |
Gerolami V et al.:
Early-onset haemochromatosis caused by a novel combination of TFR2 mutations(p.R396X/c.1538-2 A>G) in a woman of Italian descent
Haematologica
2008
93: E45-E46
|
| 19144662 |
Pelucchi S et al.:
Expression of hepcidin and other iron-related genes in type 3 hemochromatosis due to a novel mutation in transferrin receptor-2
Haematologica
2009
94: 276-279
|
| 21173098 |
Girelli D et al.:
A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis
Haematologica
2011
96: 500-506
|
| 11431687 |
Njajou OT et al.:
A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis
Nat. Genet.
2001
28: 213-214
|
| 16351644 |
Cremonesi L et al.:
Genetic and clinical heterogeneity of ferroportin disease
Br. J. Haematol.
2005
131: 663-670
|
| 15956209 |
De Domenico I et al.:
The molecular basis of ferroportin-linked hemochromatosis
Proc. Natl. Acad. Sci. U.S.A.
2005
102: 8955-8960
|
| 11518736 |
Montosi G et al.:
Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene
J. Clin. Invest.
2001
108: 619-623
|
| 10471458 |
Pietrangelo A et al.:
Hereditary hemochromatosis in adults without pathogenic mutations in the hemochromatosis gene
N. Engl. J. Med.
1999
341: 725-732
|
| 24496804 |
Moreno-Navarrete JM et al.:
Insulin resistance modulates iron-related proteins in adipose tissue
Diabetes Care
2014
37: 1092-1100
|
| 25256357 |
Shpyleva S et al.:
Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism
J. Nutr. Biochem.
2014
25: 1235-1242
|
| 21917632 |
Tajima S et al.:
Iron reduction by deferoxamine leads to amelioration of adiposity via the regulation of oxidative stress and inflammation in obese and type 2 diabetes KKAy mice
Am. J. Physiol. Endocrinol. Metab.
2012
302: E77-E86
|
| 22996660 |
Gabrielsen JS et al.:
Adipocyte iron regulates adiponectin and insulin sensitivity
J. Clin. Invest.
2012
122: 3529-3540
|
| 21880847 |
Zheng X et al.:
Hepatic iron stores are increased as assessed by magnetic resonance imaging in a Chinese population with altered glucose homeostasis
Am. J. Clin. Nutr.
2011
94: 1012-1019
|
| 23796160 |
Sam AH et al.:
Hepcidin levels in diabetes mellitus and polycystic ovary syndrome
Diabet. Med.
2013
30: 1495-1499
|
| 20497464 |
Fernandez-Real JM et al.:
Transferrin receptor-1 gene polymorphisms are associated with type 2 diabetes
Eur. J. Clin. Invest.
2010
40: 600-607
|
| 25315005 |
Simcox JA et al.:
Dietary iron controls circadian hepatic glucose metabolism through heme synthesis
Diabetes
2015
64: 1108-1119
|
| 25058155 |
Lesjak M et al.:
Quercetin inhibits intestinal iron absorption and ferroportin transporter expression in vivo and in vitro
PLoS ONE
2014
9
|
| 20354157 |
Cooksey RC et al.:
Dietary iron restriction or iron chelation protects from diabetes and loss of beta-cell function in the obese (ob/ob lep-/-) mouse
Am. J. Physiol. Endocrinol. Metab.
2010
298
|
| 17333112 |
Forouhi NG et al.:
Elevated serum ferritin levels predict new-onset type 2 diabetes: results from the EPIC-Norfolk prospective study
Diabetologia
2007
50: 949-956
|
| 17019598 |
Abraham D et al.:
Increased insulin secretory capacity but decreased insulin sensitivity after correction of iron overload by phlebotomy in hereditary haemochromatosis
Diabetologia
2006
49: 2546-2551
|
| 26106459 |
Ruiz LM et al.:
Quercetin Affects Erythropoiesis and Heart Mitochondrial Function in Mice
Oxid Med Cell Longev
2015
2015
|
| 23372018 |
Lee SH et al.:
Manganese supplementation protects against diet-induced diabetes in wild type mice by enhancing insulin secretion
Endocrinology
2013
154: 1029-1038
|
| 23241313 |
Kim J et al.:
Iron loading impairs lipoprotein lipase activity and promotes hypertriglyceridemia
FASEB J.
2013
27: 1657-1663
|
| 23046549 |
Bao W et al.:
Dietary iron intake, body iron stores, and the risk of type 2 diabetes: a systematic review and meta-analysis
BMC Med
2012
10: 119
|
| 20230395 |
et al.:
A novel missense mutation c.470 A>C (p.D157A) in the SLC40A1 gene as a cause of ferroportin disease in a family with hyperferritinaemia
Br. J. Haematol.
2010
149: 914-916
|
| 19937651 |
Griffiths WJ et al.:
Clinical presentation and molecular pathophysiology of autosomal dominant hemochromatosis caused by a novel ferroportin mutation
Hepatology
2010
51: 788-795
|
| 18160816 |
Lee PL et al.:
SLC40A1 c.1402G-->a results in aberrant splicing, ferroportin truncation after glycine 330, and an autosomal dominant hemochromatosis phenotype
Acta Haematol.
2007
118: 237-241
|
| 16258219 |
Koyama C et al.:
A Japanese family with ferroportin disease caused by a novel mutation of SLC40A1 gene: hyperferritinemia associated with a relatively low transferrin saturation of iron
Intern. Med.
2005
44: 990-993
|
| 15308612 |
Cooksey RC et al.:
Oxidative stress, beta-cell apoptosis, and decreased insulin secretory capacity in mouse models of hemochromatosis
Endocrinology
2004
145: 5305-5312
|
| 18317567 |
Jouihan HA et al.:
Iron-mediated inhibition of mitochondrial manganese uptake mediates mitochondrial dysfunction in a mouse model of hemochromatosis
Mol. Med.
2008
14: 98-108
|
| 15831700 |
Drakesmith H et al.:
Resistance to hepcidin is conferred by hemochromatosis-associated mutations of ferroportin
Blood
2005
106: 1092-1097
|
| 12730114 |
Hetet G et al.:
Molecular analyses of patients with hyperferritinemia and normal serum iron values reveal both L ferritin IRE and 3 new ferroportin (slc11A3) mutations
Blood
2003
102: 1904-1910
|
| 15692071 |
Schimanski LM et al.:
In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations
Blood
2005
105: 4096-4102
|
| 24969701 |
El-Sherbeni AA et al.:
Characterization of arachidonic acid metabolism by rat cytochrome P450 enzymes: the involvement of CYP1As
Drug Metab. Dispos.
2014
42: 1498-1507
|
| 12675279 |
Ayajiki K et al.:
Mediation of arachidonic acid metabolite(s) produced by endothelial cytochrome P-450 3A4 in monkey arterial relaxation
Hypertens. Res.
2003
26: 237-243
|
| 20702771 |
Pratt-Hyatt M et al.:
Effects of a commonly occurring genetic polymorphism of human CYP3A4 (I118V) on the metabolism of anandamide
Drug Metab. Dispos.
2010
38: 2075-2082
|
| 18344530 |
Dykens JA et al.:
In vitro assessment of mitochondrial dysfunction and cytotoxicity of nefazodone, trazodone, and buspirone
Toxicol. Sci.
2008
103: 335-345
|
| 17272674 |
Snider NT et al.:
Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides
J. Pharmacol. Exp. Ther.
2007
321: 590-597
|
| 19171674 |
Snider NT et al.:
A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonist
Mol. Pharmacol.
2009
75: 965-972
|
| 16723661 |
Liu S et al.:
The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP
RNA
2006
12: 1418-1430
|
| 8652672 |
Kimura K et al.:
Modification of the alternative splicing process of testosterone-repressed prostate message-2 (TRPM-2) gene by protein synthesis inhibitors and heat shock treatment
Biochim. Biophys. Acta
1996
1307: 83-88
|
| 25783052 |
Na JY et al.:
Hepatoprotective effect of phosphatidylcholine against carbon tetrachloride liver damage in mice
Biochem Biophys Res Commun
2015
460: 308-313
|
| 17851469 |
Huls M et al.:
P-glycoprotein-deficient mice have proximal tubule dysfunction but are protected against ischemic renal injury
Kidney Int.
2007
72: 1233-1241
|
| 18801732 |
Horike N et al.:
AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver
J. Biol. Chem.
2008
283
|
| 11879638 |
Yun Z et al.:
Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia
Dev. Cell
2002
2: 331-341
|
| 25503986 |
Sato Y et al.:
Moderate hypoxia induces beta-cell dysfunction with HIF-1-independent gene expression changes
PLoS ONE
2014
9
|
| 25762623 |
Jhuang HJ et al.:
Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1alpha-dependent pathway
Oncotarget
2015
6: 7788-7803
|
| 16531007 |
Aggeli IK et al.:
Involvement of JNKs and p38-MAPK/MSK1 pathways in H2O2-induced upregulation of heme oxygenase-1 mRNA in H9c2 cells
Cell. Signal.
2006
18: 1801-1812
|
| 22139554 |
Patterson AJ et al.:
Hypoxia-derived oxidative stress mediates epigenetic repression of PKCepsilon gene in foetal rat hearts
Cardiovasc. Res.
2012
93: 302-310
|
| 22814763 |
Raddatz K et al.:
Deletion of protein kinase Cepsilon in mice has limited effects on liver metabolite levels but alters fasting ketogenesis and gluconeogenesis
Diabetologia
2012
55: 2789-2793
|
| 25157809 |
Gogoi B et al.:
A polyphenol rescues lipid induced insulin resistance in skeletal muscle cells and adipocytes
Biochem. Biophys. Res. Commun.
2014
452: 382-388
|
| 20198332 |
Shankar E et al.:
PKCepsilon induces Bcl-2 by activating CREB
Int. J. Oncol.
2010
36: 883-888
|
| 22907731 |
Karnes JH et al.:
Association of KCNJ1 variation with change in fasting glucose and new onset diabetes during HCTZ treatment
Pharmacogenomics J.
2013
13: 430-436
|
| 24122840 |
Gong Y et al.:
PROX1 gene variant is associated with fasting glucose change after antihypertensive treatment
Pharmacotherapy
2014
34: 123-130
|
| 24128935 |
Karnes JH et al.:
Impact of TCF7L2 single nucleotide polymorphisms on hydrochlorothiazide-induced diabetes
Pharmacogenet. Genomics
2013
23: 697-705
|
| 25201287 |
Del-Aguila JL et al.:
Transethnic meta-analysis suggests genetic variation in the HEME pathway influences potassium response in patients treated with hydrochlorothiazide
Pharmacogenomics J.
2015
15: 153-157
|
| 25887158 |
Vartak R et al.:
Redefining the roles of mitochondrial DNA-encoded subunits in respiratory Complex I assembly
Biochim. Biophys. Acta
2015
1852: 1531-1539
|
| 18501722 |
Wanninger J et al.:
Metformin reduces cellular lysophosphatidylcholine and thereby may lower apolipoprotein B secretion in primary human hepatocytes
Biochim. Biophys. Acta
2008
1781: 321-325
|
| 22982378 |
Hochrath K et al.:
The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis
FASEB J.
2012
26: 5081-5091
|
| 20120088 |
Boulpaep E et al.:
Protein-protein interactions among ion channels regulate ion transport in the kidney
Bull. Mem. Acad. R. Med. Belg.
2009
164: 133-141
|
| 23179379 |
Siraskar B et al.:
Downregulation of the renal outer medullary K(+) channel ROMK by the AMP-activated protein kinase
Pflugers Arch.
2013
465: 233-245
|
| 22811560 |
Foster DB et al.:
Mitochondrial ROMK channel is a molecular component of mitoK(ATP)
Circ. Res.
2012
111: 446-454
|
| 18789903 |
Tseng PC et al.:
Helioxanthin inhibits interleukin-1 beta-induced MIP-1 beta production by reduction of c-jun expression and binding of the c-jun/CREB1 complex to the AP-1/CRE site of the MIP-1 beta promoter in Huh7 cells
Biochem. Pharmacol.
2008
76: 1121-1133
|
| 18982348 |
Gamba G et al.:
Thick ascending limb: the Na(+):K (+):2Cl (-) co-transporter, NKCC2, and the calcium-sensing receptor, CaSR
Pflugers Arch.
2009
458: 61-76
|
| 11083864 |
Yamagishi S et al.:
p38 mitogen-activated protein kinase regulates low potassium-induced c-Jun phosphorylation and apoptosis in cultured cerebellar granule neurons
J. Biol. Chem.
2001
276: 5129-5133
|
| 9148963 |
Zhang C et al.:
Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells. Indications of communication between p38 and p42 MAP kinases
J. Biol. Chem.
1997
272
|
| 21967062 |
Quazi F et al.:
Lipid transport by mammalian ABC proteins
Essays Biochem.
2011
50: 265-290
|
| 12150997 |
Baek SH et al.:
Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein
Cell
2002
110: 55-67
|
| 11877414 |
Mbebi C et al.:
Amyloid precursor protein family-induced neuronal death is mediated by impairment of the neuroprotective calcium/calmodulin protein kinase IV-dependent signaling pathway
J. Biol. Chem.
2002
277
|
| 25887459 |
Salilew-Wondim D et al.:
Polycystic ovarian syndrome is accompanied by repression of gene signatures associated with biosynthesis and metabolism of steroids, cholesterol and lipids
J Ovarian Res
2015
8: 24
|
| 24222346 |
Neuschafer-Rube F et al.:
The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes
Diabetes
2014
63: 1048-1057
|
| 26086111 |
Singh S et al.:
ALDH1B1 links alcohol consumption and diabetes
Biochem. Biophys. Res. Commun.
2015
463: 768-773
|
| 22975078 |
Li Q et al.:
Activation of Akt through 5-HT2A receptor ameliorates serotonin-induced degradation of insulin receptor substrate-1 in adipocytes
Mol. Cell. Endocrinol.
2013
365: 25-35
|
| 7992257 |
Malyszko J et al.:
Daily variations of platelet aggregation in relation to blood and plasma serotonin in diabetes
Thromb. Res.
1994
75: 569-576
|
| 9383015 |
Ikemoto K et al.:
Monoamine oxidase B (MAOB)-containing structures in MAOA-deficient transgenic mice
Brain Res.
1997
771: 121-132
|
| 26206285 |
Bennet H et al.:
Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes
Peptides
2015
71: 113-120
|
| 21711335 |
Lee HJ et al.:
Serotonin induces melanogenesis via serotonin receptor 2A
Br. J. Dermatol.
2011
165: 1344-1348
|
| 23105096 |
Li C et al.:
Rab26 modulates the cell surface transport of alpha2-adrenergic receptors from the Golgi
J. Biol. Chem.
2012
287
|
| 26411342 |
Pfluger PT et al.:
Calcineurin Links Mitochondrial Elongation with Energy Metabolism
|
| 23166628 |
Ampuero J et al.:
Metformin inhibits glutaminase activity and protects against hepatic encephalopathy
PLoS ONE
2012
7
|
| 15089745 |
Baglietto-Vargas D et al.:
Segregation of two glutaminase isoforms in islets of Langerhans
Biochem. J.
2004
381: 483-487
|
| 8524402 |
Kissinger CR et al.:
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
Nature
1995
378: 641-644
|
| 26366137 |
Yokoi N et al.:
Identification of putative biomarkers for prediabetes by metabolome analysis of rat models of type 2 diabetes
Metabolomics
2015
11: 1277-1286
|
| 23813101 |
Oxenkrug G et al.:
Insulin resistance and dysregulation of tryptophan-kynurenine and kynurenine-nicotinamide adenine dinucleotide metabolic pathways
Mol. Neurobiol.
2013
48: 294-301
|
| 23514379 |
Oxenkrug G et al.:
Serotonin-kynurenine hypothesis of depression: historical overview and recent developments
Curr Drug Targets
2013
14: 514-521
|
| 15365617 |
Reimann F et al.:
Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells
Diabetologia
2004
47: 1592-1601
|
| 21209017 |
Tolhurst G et al.:
Glutamine triggers and potentiates glucagon-like peptide-1 secretion by raising cytosolic Ca2+ and cAMP
Endocrinology
2011
152: 405-413
|
| 20645222 |
Tomas E et al.:
GLP-1 (9-36) amide metabolite suppression of glucose production in isolated mouse hepatocytes
Horm. Metab. Res.
2010
42: 657-662
|
| 22015237 |
Lind M et al.:
Glucagon-like peptide 1 (GLP-1) analogue combined with insulin reduces HbA1c and weight with low risk of hypoglycemia and high treatment satisfaction
Prim Care Diabetes
2012
6: 41-46
|
| 21663496 |
Esposito K et al.:
GLP-1 receptor agonists and HBA1c target of <7% in type 2 diabetes: meta-analysis of randomized controlled trials
Curr Med Res Opin
2011
27: 1519-1528
|
| 25412338 |
Samocha-Bonet D et al.:
Glycemic effects and safety of L-Glutamine supplementation with or without sitagliptin in type 2 diabetes patients-a randomized study
PLoS ONE
2014
9
|
| 11533302 |
Reeds PJ et al.:
Glutamine and the bowel
J. Nutr.
2001
131: 2505
|
| 26097706 |
Fujii Y et al.:
Ingestion of coffee polyphenols increases postprandial release of the active glucagon-like peptide-1 (GLP-1(7-36)) amide in C57BL/6J mice
J Nutr Sci
2015
4: E9
|
| 15655705 |
Deacon CF et al.:
Circulation and degradation of GIP and GLP-1
Horm. Metab. Res.
2004
36: 761-765
|
| 25070829 |
Zou CY et al.:
Metabolic signaling of insulin secretion by pancreatic beta-cell and its derangement in type 2 diabetes
Eur Rev Med Pharmacol Sci
2014
18: 2215-2227
|
| 16365092 |
Shimomura Y et al.:
Branched-chain amino acid catabolism in exercise and liver disease
J. Nutr.
2006
1: Suppl 250S-253S
|
| 25287287 |
Lynch CJ et al.:
Branched-chain amino acids in metabolic signalling and insulin resistance
Nat Rev Endocrinol
2014
10: 723-736
|
| 26393786 |
van den Berg R et al.:
A single night of sleep curtailment increases plasma acylcarnitines: Novel insights in the relationship between sleep and insulin resistance
|
| 26473975 |
Schwab S et al.:
Intake of Vitamin and Mineral Supplements and Longitudinal Association with HbA1c Levels in the General Non-Diabetic Population-Results from the MONICA/KORA S3/F3 Study
PLoS ONE
2015
10
|
| 22013018 |
Mutel E et al.:
Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon
Diabetes
2011
60: 3121-3131
|
| 20546255 |
Gerich JE et al.:
Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: therapeutic implications
Diabet. Med.
2010
2: 136-142
|
| 11788376 |
Meyer C et al.:
Renal substrate exchange and gluconeogenesis in normal postabsorptive humans
Am. J. Physiol. Endocrinol. Metab.
2002
282: E428-E434
|
| 14559723 |
Mithieux G et al.:
Induction of control genes in intestinal gluconeogenesis is sequential during fasting and maximal in diabetes
Am. J. Physiol. Endocrinol. Metab.
2004
286: E370-E375
|
| 23466304 |
Mendez-Lucas A et al.:
PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis
J. Hepatol.
2013
59: 105-113
|
| 19996311 |
Regazzetti C et al.:
Insulin induces REDD1 expression through hypoxia-inducible factor 1 activation in adipocytes
J. Biol. Chem.
2010
285: 5157-5164
|
| 19567526 |
Nedeltcheva AV et al.:
Exposure to recurrent sleep restriction in the setting of high caloric intake and physical inactivity results in increased insulin resistance and reduced glucose tolerance
J. Clin. Endocrinol. Metab.
2009
94: 3242-3250
|
| 26251408 |
Xu T et al.:
Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes
Diabetes Care
2015
38: 1858-1867
|
| 26352407 |
Raffler J et al.:
Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality
PLoS Genet.
2015
11
|
| 23206674 |
Kalapos MP et al.:
Where does plasma methylglyoxal originate from? }, authors { names std { { name ml Kalapos MP, affil str Theoretical Biology Research Group, Budapest, Hungary. mpkalapos@freemail.hu } } }, from journal { title { iso-jta Diabetes Res. Clin. Pract
Diabetes Res. Clin. Pract.
2013
99: 260-271
|
| 9892243 |
Beisswenger PJ et al.:
Metformin reduces systemic methylglyoxal levels in type 2 diabetes
Diabetes
1999
48: 198-202
|
| 22355255 |
Bahmani F et al.:
Glycine therapy inhibits the progression of cataract in streptozotocin-induced diabetic rats
Mol. Vis.
2012
18: 439-448
|
| 6162456 |
author information missing
Polyamine and amino acid content, and activity of polyamine-synthesizing decarboxylases, in liver of streptozotocin-induced diabetic and insulin-treated diabetic rats
Biochem. J.
1980
190: 395-403
|
| 3138983 |
Hetenyi G Jr et al.:
Gluconeogenesis from glycine and serine in fasted normal and diabetic rats
Biochem. J.
1988
253: 27-32
|
| 26171623 |
Lehmann R et al.:
Metabolic profiles during an oral glucose tolerance test in pregnant women with and without gestational diabetes
Exp. Clin. Endocrinol. Diabetes
2015
123: 483-438
|
| 24698665 |
Dudzik D et al.:
Metabolic fingerprint of Gestational Diabetes Mellitus
J Proteomics
2014
103: 57-71
|
| 20393151 |
Takashima M et al.:
Role of KLF15 in regulation of hepatic gluconeogenesis and metformin action
Diabetes
2010
59: 1608-1615
|
| 10827342 |
Rioux V et al.:
Myristic acid, unlike palmitic acid, is rapidly metabolized in cultured rat hepatocytes
J. Nutr. Biochem.
2000
11: 198-207
|
| 21399626 |
Xiao B et al.:
Structure of mammalian AMPK and its regulation by ADP
Nature
2011
472: 230-233
|
| 17578454 |
Dawson RJ et al.:
Uptake or extrusion: crystal structures of full ABC transporters suggest a common mechanism
Mol. Microbiol.
2007
65: 250-257
|
| 25084564 |
Auciello FR et al.:
Oxidative stress activates AMPK in cultured cells primarily by increasing cellular AMP and/or ADP
FEBS Lett.
2014
588: 3361-3366
|
| 20093281 |
Caton PW et al.:
Metformin suppresses hepatic gluconeogenesis through induction of SIRT1 and GCN5
J. Endocrinol.
2010
205: 97-106
|
| 17909097 |
Kim YD et al.:
Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP
Diabetes
2008
57: 306-314
|
| 15371448 |
Zang M et al.:
AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells
J. Biol. Chem.
2004
279
|
| 16873691 |
Bandyopadhyay GK et al.:
Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects
Diabetes
2006
55: 2277-2285
|
| 18842111 |
Ben Djoudi Ouadda A et al.:
Increased hepatic lipogenesis in insulin resistance and Type 2 diabetes is associated with AMPK signalling pathway up-regulation in Psammomys obesus
Biosci. Rep.
2009
29: 283-292
|
| 21083698 |
Zhang CX et al.:
Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats
Clin. Exp. Pharmacol. Physiol.
2011
38: 55-62
|
| 16380484 |
Kukidome D et al.:
Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells
Diabetes
2006
55: 120-127
|
| 19056992 |
Palomba S et al.:
Evidence-based and potential benefits of metformin in the polycystic ovary syndrome: a comprehensive review
Endocr. Rev.
2009
30: 1-50
|
| 12749437 |
Mansfield R et al.:
Metformin has direct effects on human ovarian steroidogenesis
Fertil. Steril.
2003
79: 956-962
|
| 26633628 |
Forslund K et al.:
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
Nature
2015
528: 262-266
|
| 26580014 |
Bapat SP et al.:
Depletion of fat-resident Treg cells prevents age-associated insulin resistance
Nature
2015
528: 137-141
|
| 25457619 |
Vieira E et al.:
Clock genes, pancreatic function, and diabetes
Trends Mol Med
2014
20: 685-693
|
| 25715415 |
Shan Z et al.:
Sleep duration and risk of type 2 diabetes: a meta-analysis of prospective studies
Diabetes Care
2015
38: 529-537
|
| 26668142 |
Keskin A et al.:
Effects of Sleep Disorders on Hemoglobin A1c Levels in Type 2 Diabetic Patients
Chin. Med. J.
2015
128: 3292-3297
|
| 25623152 |
Larcher S et al.:
Sleep habits and diabetes
Diabetes Metab.
2015
41: 263-271
|
| 26576055 |
Bernsmeier C et al.:
Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: A Comparison with Healthy Controls
PLoS ONE
2015
10
|
| 22968146 |
Barnea M et al.:
Metformin affects the circadian clock and metabolic rhythms in a tissue-specific manner
Biochim. Biophys. Acta
2012
1822: 1796-1806
|
| 24236897 |
Kajbaf F et al.:
The relationship between metformin therapy and sleep quantity and quality in patients with Type 2 diabetes referred for potential sleep disorders
Diabet. Med.
2014
31: 577-580
|
| 22701848 |
Wiwanitkit S et al.:
Metformin and sleep disorders
Indian J Endocrinol Metab
2012
16: S63-S64
|
| 8269798 |
Giugliano D et al.:
Metformin improves glucose, lipid metabolism, and reduces blood pressure in hypertensive, obese women
Diabetes Care
1993
16: 1387-1390
|
| 9702467 |
Scarpello JH et al.:
Effect of metformin on bile salt circulation and intestinal motility in type 2 diabetes mellitus
Diabet. Med.
1998
15: 651-656
|
| 20522594 |
Kars M et al.:
Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women
Diabetes
2010
59: 1899-1905
|
| 23505172 |
Malin SK et al.:
Metformin modifies the exercise training effects on risk factors for cardiovascular disease in impaired glucose tolerant adults
Obesity (Silver Spring)
2013
21: 93-100
|
| 24988476 |
Napolitano A et al.:
Novel gut-based pharmacology of metformin in patients with type 2 diabetes mellitus
PLoS ONE
2014
9
|
| 25527624 |
Forouzandeh F et al.:
Metformin beyond diabetes: pleiotropic benefits of metformin in attenuation of atherosclerosis
J Am Heart Assoc
2014
3
|
| 26068179 |
Zhang C et al.:
Differential response in levels of high-density lipoprotein cholesterol to one-year metformin treatment in prediabetic patients by race/ethnicity
Cardiovasc Diabetol
2015
14: 79
|
| 26587028 |
Rajabi S et al.:
Effect of Low Glycemic Index Diet Versus Metformin on Metabolic Syndrome
Int J Endocrinol Metab
2015
13
|
| 21525463 |
Handelsman Y et al.:
Role of bile acid sequestrants in the treatment of type 2 diabetes
Diabetes Care
2011
34: S244-S250
|
| 26197999 |
Rudling M et al.:
Specific inhibition of bile acid transport alters plasma lipids and GLP-1
BMC Cardiovasc Disord
2015
15: 75
|
| 22701567 |
Bonnefond A et al.:
Whole-exome sequencing and high throughput genotyping identified KCNJ11 as the thirteenth MODY gene
PLoS ONE
2012
7
|
| 26579438 |
Ferrebee CB et al.:
Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids
Acta Pharm Sin B
2015
5: 129-134
|
| 873086 |
et al.:
Alteration of bile acid metabolism and vitamin-B12-absorption in diabetics on biguanides
Diabetologia
1977
13: 187-193
|
| 4701477 |
author information missing
Inhibition of intestinal amino acid transport by blood sugar lowering biguanides
Diabetologia
1973
9: 6-12
|
| 24959880 |
Liu Q et al.:
Vitamin B12 status in metformin treated patients: systematic review
PLoS ONE
2014
9
|
| 24531544 |
et al.:
Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk
J. Clin. Invest.
2014
3: 1037-1051
|
| 24531544 |
author information missing
Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk
J. Clin. Invest.
2014
124: 1037-1051
|
| 15784703 |
Yorifuji T et al.:
The C42R mutation in the Kir6.2 (KCNJ11) gene as a cause of transient neonatal diabetes, childhood diabetes, or later-onset, apparently type 2 diabetes mellitus
J. Clin. Endocrinol. Metab.
2005
90: 3174-3178
|
| 24018988 |
Liu L et al.:
Mutations in KCNJ11 are associated with the development of autosomal dominant, early-onset type 2 diabetes
Diabetologia
2013
56: 2609-2618
|
| 26108617 |
Ritter O et al.:
Lipid-mediated muscle insulin resistance: different fat, different pathways? }, authors { names std { { name ml Ritter O, affil str Institute for Clinical Diabetology, German Diabetes Center, c/o Aufm Hennekamp 65, D-40225, Dusseldorf, Germany
J. Mol. Med.
2015
93: 831-843
|
| 24214972 |
Chavez JA et al.:
Ceramides and glucosylceramides are independent antagonists of insulin signaling
J. Biol. Chem.
2014
289: 723-734
|
| 26038579 |
Herzer S et al.:
Fasting-Induced Lipolysis and Hypothalamic Insulin Signaling Are Regulated by Neuronal Glucosylceramide Synthase
Diabetes
2015
64: 3363-3376
|
| 23909401 |
van den Bout I et al.:
Collaboration of AMPK and PKC to induce phosphorylation of Ser413 on PIP5K1B resulting in decreased kinase activity and reduced PtdIns(4,5)P2 synthesis in response to oxidative stress and energy restriction
Biochem. J.
2013
455: 347-358
|
| 26728692 |
Junker AE et al.:
Diabetic and nondiabetic patients with nonalcoholic fatty liver disease have an impaired incretin effect and fasting hyperglucagonaemia
|
| 26974008 |
Huypens P et al.:
Epigenetic germline inheritance of diet-induced obesity and insulin resistance
Nat. Genet.
2016
48: 497-499
|
| 26833246 |
Lu Y et al.:
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Nat Commun
2016
7: 10495
|
| 26073777 |
Prudente S et al.:
Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus
Am. J. Hum. Genet.
2015
97: 177-185
|
| 24067359 |
O'Neil D et al.:
Dysregulation of Npas2 leads to altered metabolic pathways in a murine knockout model
Mol. Genet. Metab.
2013
110: 378-387
|
| 24831725 |
Takeda Y et al.:
Retinoic acid-related orphan receptor gamma (RORgamma): a novel participant in the diurnal regulation of hepatic gluconeogenesis and insulin sensitivity
PLoS Genet.
2014
10
|
| 25212631 |
Lee SM et al.:
Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolism
Hepatology
2015
61: 497-505
|
| 11006284 |
Iwanishi M et al.:
The protein-tyrosine kinase fer associates with signaling complexes containing insulin receptor substrate-1 and phosphatidylinositol 3-kinase
J. Biol. Chem.
2000
275
|
| 22841001 |
Feng D et al.:
Clocks, metabolism, and the epigenome
Mol. Cell
2012
47: 158-167
|
| 27044075 |
Yu H et al.:
Extended synaptotagmins are Ca2+-dependent lipid transfer proteins at membrane contact sites
Proc. Natl. Acad. Sci. U.S.A.
2016
16: 4362-4367
|
| 23791178 |
Giordano F et al.:
PI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins
Cell
2013
153: 1494-1509
|
| 23393134 |
Walkinshaw DR et al.:
The tumor suppressor kinase LKB1 activates the downstream kinases SIK2 and SIK3 to stimulate nuclear export of class IIa histone deacetylases
J. Biol. Chem.
2013
288: 9345-9362
|
| 22662228 |
Uebi T et al.:
Involvement of SIK3 in glucose and lipid homeostasis in mice
PLoS ONE
2012
5
|
| 22547676 |
Hoffmann A et al.:
Transient neonatal diabetes mellitus gene Zac1 impairs insulin secretion in mice through Rasgrf1
Mol. Cell. Biol.
2012
32: 2549-2560
|
| 12805218 |
Font de Mora J et al.:
Ras-GRF1 signaling is required for normal beta-cell development and glucose homeostasis
EMBO J.
2003
22: 3039-3049
|
| 27491375 |
Herder C et al.:
Biomarkers of subclinical inflammation and increases in glycaemia, insulin resistance and beta-cell function in non-diabetic individuals: the Whitehall II study
|
| 21199859 |
Hatanaka M et al.:
Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic beta-cells
Hum. Mol. Genet.
2011
20: 1274-1284
|
| 27053292 |
Ivask M et al.:
RNA-sequencing of WFS1-deficient pancreatic islets
|
| 26379490 |
Tein K et al.:
Prohormone convertase 2 activity is increased in the hippocampus of Wfs1 knockout mice
Front Mol Neurosci
2015
8: 45
|
| 26154755 |
Hsieh CJ et al.:
Sequence variants of the aging gene CISD2 and the risk for Alzheimers disease
J. Formos. Med. Assoc.
2015
114: 627-632
|
| 19451219 |
Chen YF et al.:
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
Genes Dev.
2009
23: 1183-1194
|
| 23717386 |
Tamir S et al.:
Nutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugs
PLoS ONE
2013
8
|
| 26387034 |
Lin CC et al.:
CISD2 serves a novel role as a suppressor of nitric oxide signalling and curcumin increases CISD2 expression in spinal cord injuries
Injury
2015
46: 2341-2350
|
| 24833725 |
Wang CH et al.:
Cisd2 modulates the differentiation and functioning of adipocytes by regulating intracellular Ca2+ homeostasis
Hum. Mol. Genet.
2014
23: 4770-4785
|
| 22617439 |
Chang NC et al.:
BCL2-CISD2: An ER complex at the nexus of autophagy and calcium homeostasis? }, authors { names std { { name ml Chang NC, affil str Department of Biochemistry and Goodman Cancer Research Center, McGill University, Montreal, Quebec, Canada
Autophagy
2012
8: 856-857
|
| 22661501 |
Wu CY et al.:
A persistent level of Cisd2 extends healthy lifespan and delays aging in mice
Hum. Mol. Genet.
2012
21: 3956-3968
|
| 24974737 |
Wang CH et al.:
Cisd2 mediates lifespan: is there an interconnection among Ca(2)(+) homeostasis, autophagy, and lifespan? }, authors { names std { { name ml Wang CH, affil str Institute of Biochemistry and Molecular Biology, School of Life Science, National Yang-Ming University , Taipei , Taiwan
Free Radic. Res.
2014
48: 1109-1114
|
| 17846994 |
Amr S et al.:
A homozygous mutation in a novel zinc-finger protein, ERIS, is responsible for Wolfram syndrome 2
Am. J. Hum. Genet.
2007
81: 673-683
|
| 25056293 |
Mozzillo E et al.:
A novel CISD2 intragenic deletion, optic neuropathy and platelet aggregation defect in Wolfram syndrome type 2
BMC Med. Genet.
2014
15: 88
|
| 2573522 |
Accili D et al.:
A mutation in the insulin receptor gene that impairs transport of the receptor to the plasma membrane and causes insulin-resistant diabetes
EMBO J.
1989
8: 2509-2517
|
| 11757582 |
Longo N et al.:
Decreased half-life of insulin-like growth factor I in Rabson-Mendenhall syndrome
J. Inherit. Metab. Dis.
2001
24: 546-550
|
| 12023989 |
Longo N et al.:
Genotype-phenotype correlation in inherited severe insulin resistance
Hum. Mol. Genet.
2002
11: 1465-1475
|
| 24819547 |
Amaral FG et al.:
Melatonin synthesis impairment as a new deleterious outcome of diabetes-derived hyperglycemia
J. Pineal Res.
2014
57: 67-79
|
| 27621107 |
Adam J et al.:
Metformin Effect on Non-Targeted Metabolite Profiles in Patients with Type 2 Diabetes and Multiple Murine Tissues
|
| 16082501 |
Curis E et al.:
Almost all about citrulline in mammals
Amino Acids
2005
29: 177-205
|
| 27190086 |
Kovamees O et al.:
Amino acid metabolism reflecting arginase activity is increased in patients with type 2 diabetes and associated with endothelial dysfunction
Diab Vasc Dis Res
2016
13: 354-360
|
| 26331226 |
Sharma S et al.:
The role of melatonin in diabetes: therapeutic implications
Arch Endocrinol Metab
2015
59: 391-399
|
| 16150114 |
Bach AG et al.:
Melatonin stimulates inositol-1,4,5-trisphosphate and Ca2+ release from INS1 insulinoma cells
J. Pineal Res.
2005
39: 316-323
|
| 16842543 |
Ha E et al.:
Melatonin stimulates glucose transport via insulin receptor substrate-1/phosphatidylinositol 3-kinase pathway in C2C12 murine skeletal muscle cells
J. Pineal Res.
2006
41: 67-72
|
| 25548489 |
Wang XC et al.:
MicroRNA-185 regulates expression of lipid metabolism genes and improves insulin sensitivity in mice with non-alcoholic fatty liver disease
World J. Gastroenterol.
2014
20
|
| 20651284 |
Zampetaki A et al.:
Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes
Circ. Res.
2010
107: 810-817
|
| 25733201 |
Irving BA et al.:
Effect of insulin sensitizer therapy on amino acids and their metabolites
Metab. Clin. Exp.
2015
64: 720-728
|
| 25944670 |
Elgheznawy A et al.:
Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes
Circ. Res.
2015
117: 157-165
|
| 24908639 |
et al.:
|
| 21829658 |
Karolina DS et al.:
MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus
PLoS ONE
2011
6
|
| 27194924 |
Song K et al.:
Anti-diabetic Effect of Fermented Milk Containing Conjugated Linoleic Acid on Type II Diabetes Mellitus
Korean J Food Sci Anim Resour
2016
36: 170-177
|
| 25895678 |
Sartorius T et al.:
Mice Lacking Free Fatty Acid Receptor 1 (GPR40/FFAR1) are Protected Against Conjugated Linoleic Acid-Induced Fatty Liver but Develop Inflammation and Insulin Resistance in the Brain
Cell. Physiol. Biochem.
2015
35: 2272-2284
|
| 12972681 |
Hargrave KM et al.:
Conjugated linoleic acid does not improve insulin tolerance in mice
Obes. Res.
2003
11: 1104-1115
|
| 21339298 |
Schmidt J et al.:
Conjugated linoleic acids mediate insulin release through islet G protein-coupled receptor FFA1/GPR40
J. Biol. Chem.
2011
286
|
| 17466453 |
Cao ZP et al.:
Intracerebroventricular administration of conjugated linoleic acid (CLA) inhibits food intake by decreasing gene expression of NPY and AgRP
Neurosci. Lett.
2007
418: 217-221
|
| 21598254 |
Liu Y et al.:
Deficient brain insulin signalling pathway in Alzheimers disease and diabetes
J. Pathol.
2011
1: 54-62
|
| 25269915 |
Li Z et al.:
Glycogen synthase kinase-3: a key kinase in retinal neuron apoptosis in early diabetic retinopathy
Chin. Med. J.
2014
127: 3464-3470
|
| 25724107 |
Shang G et al.:
Sulforaphane attenuation of experimental diabetic nephropathy involves GSK-3 beta/Fyn/Nrf2 signaling pathway
J. Nutr. Biochem.
2015
26: 596-606
|
| 27284338 |
Zhou YX et al.:
Effects of a GSK-3beta inhibitor on the renal expression levels of RANK, RANKL and NF-kappaB in a rat model of diabetic nephropathy
Exp Ther Med
2016
11: 2495-2502
|
| 24983010 |
Qu ZS et al.:
Glycogen synthase kinase-3 regulates production of amyloid-beta peptides and tau phosphorylation in diabetic rat brain
ScientificWorldJournal
2014
2014
|
| 26722385 |
Qi J et al.:
Roles of TNF-alpha, GSK-3beta and RANKL in the occurrence and development of diabetic osteoporosis
Int J Clin Exp Pathol
2015
8
|
| 23051669 |
Xia Y et al.:
Lithium exacerbates hepatic ischemia/reperfusion injury by inhibiting GSK-3beta/NF-kappaB-mediated protective signaling in mice
Eur. J. Pharmacol.
2012
697: 117-125
|
| 27656397 |
Lee SH et al.:
Insulin in the nervous system and the mind: Functions in metabolism, memory, and mood
Mol Metab
2016
5: 589-601
|
| 19954947 |
Kennedy A et al.:
Antiobesity mechanisms of action of conjugated linoleic acid
J. Nutr. Biochem.
2010
21: 171-179
|
| 25841249 |
Bhaswant M et al.:
Mechanisms of enhanced insulin secretion and sensitivity with n-3 unsaturated fatty acids
J. Nutr. Biochem.
2015
26: 571-584
|
| 26858121 |
Barini E et al.:
Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy
Mol Neurodegener
2016
11: 16
|
| 27509335 |
Picone P et al.:
Biological and biophysics aspects of metformin-induced effects: cortex mitochondrial dysfunction and promotion of toxic amyloid pre-fibrillar aggregates
Aging (Albany NY)
2016
8: 1718-1734
|
| 27127460 |
Maiese K et al.:
Novel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTOR
Neural Regen Res
2016
3: 372-385
|
| 26706021 |
Diaz-Gerevini GT et al.:
Beneficial action of resveratrol: How and why? }, authors { names std { { name ml Diaz-Gerevini GT, affil str Biologia Celular, Histologia y Embriologia, Facultad de Ciencias Medicas, INICSA (CONICET-Universidad Nacional de Cordoba), Cordoba, Argentina
Nutrition
2016
2: 174-178
|
| 25667085 |
Picone P et al.:
Metformin increases APP expression and processing via oxidative stress, mitochondrial dysfunction and NF-kappaB activation: Use of insulin to attenuate metformins effect
Biochim. Biophys. Acta
2015
1853: 1046-1059
|
| 24862430 |
Guo M et al.:
Metformin may produce antidepressant effects through improvement of cognitive function among depressed patients with diabetes mellitus
Clin. Exp. Pharmacol. Physiol.
2014
41: 650-656
|
| 26041775 |
Kang GM et al.:
Leptin Elongates Hypothalamic Neuronal Cilia via Transcriptional Regulation and Actin Destabilization
J. Biol. Chem.
2015
290
|
| 26900135 |
Sarparanta J et al.:
Autophagy and Mitochondria in Obesity and Type 2 Diabetes
Curr Diabetes Rev
2017
13: 352-369
|
| 19165168 |
Sakamoto K et al.:
Proteasome subunits mRNA expressions correlate with male BMI: implications for a role in obesity
Obesity (Silver Spring)
2009
17: 1044-1049
|
| 22818443 |
author information missing
article information missing
|
| 9535724 |
author information missing
article information missing
|
| 15159252 |
author information missing
article information missing
|
| 9915872 |
et al.:
|
| 11110851 |
author information missing
article information missing
|
| 17313718 |
author information missing
article information missing
|
| 25406998 |
et al.:
|
| 28090346 |
author information missing
article information missing
|
| 15538969 |
Brotto MA et al.:
Defective maintenance of intracellular Ca2+ homeostasis is linked to increased muscle fatigability in the MG29 null mice
Cell Res.
2004
5: 373-378
|
| 14559251 |
et al.:
|
| 25805502 |
Li J et al.:
Insulin resistance induces posttranslational hepatic sortilin 1 degradation in mice
J. Biol. Chem.
2015
18
|
| 27881673 |
Li J et al.:
Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1
J. Biol. Chem.
2017
292: 146-160
|
| 18193044 |
Kathiresan S et al.:
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
Nat. Genet.
2008
40: 189-197
|
| 22466652 |
Ai D et al.:
Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice
J. Clin. Invest.
2012
5: 1677-1687
|
| 24583181 |
Livinskaya VA et al.:
Immunoaffinity purification of the functional 20S proteasome from human cells via transient overexpression of specific proteasome subunits
Protein Expr. Purif.
2014
97: 37-43
|
| 28061459 |
Sun YX et al.:
Association between PPAP2B gene polymorphisms and coronary heart disease susceptibility in Chinese Han males and females
|
| 27029739 |
Bacos K et al.:
Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes
Nat Commun
2016
7: 11089
|
| 25502755 |
Yuan W et al.:
An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins
Nat Commun
2014
5: 5719
|
| 15147912 |
Sakakibara T et al.:
Identification and characterization of a novel Rho GTPase activating protein implicated in receptor-mediated endocytosis
FEBS Lett.
2004
1-3: 294-300
|
| 18155003 |
Abisi S et al.:
Cysteine protease activity in the wall of abdominal aortic aneurysms
J. Vasc. Surg.
2007
46: 1260-1266
|
| 22578325 |
Williams SR et al.:
Smith-Magenis syndrome results in disruption of CLOCK gene transcription and reveals an integral role for RAI1 in the maintenance of circadian rhythmicity
Am. J. Hum. Genet.
2012
6: 941-949
|
| 25889123 |
Fan K et al.:
The induction of neuronal death by up-regulated microglial cathepsin H in LPS-induced neuroinflammation
J Neuroinflammation
2015
12: 54
|
| 27998776 |
Oda K et al.:
Follicular thyroglobulin induces cathepsin H expression and activity in thyrocytes
Biochem. Biophys. Res. Commun.
2017
483: 541-546
|
| 17956944 |
Williams C et al.:
Targeting of the type II inositol polyphosphate 5-phosphatase INPP5B to the early secretory pathway
J. Cell. Sci.
2007
120: 3941-3951
|
| 26862211 |
Eramo MJ et al.:
Regulation of PtdIns(3,4,5)P3/Akt signalling by inositol polyphosphate 5-phosphatases
Biochem. Soc. Trans.
2016
1: 240-252
|
| 27554474 |
Thomsen SK et al.:
Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants
Diabetes
2016
65: 3805-3811
|
| 26048236 |
Kruse R et al.:
Markers of autophagy are adapted to hyperglycaemia in skeletal muscle in type 2 diabetes
Diabetologia
2015
58: 2087-2095
|
| 20858501 |
Dorn GW 2nd et al.:
Nix Nought Nothing: fairy tale or real deal
J. Mol. Cell. Cardiol.
2011
4: 497-500
|
| 12048257 |
Danesh FR et al.:
3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy
Proc. Natl. Acad. Sci. U.S.A.
2002
99: 8301-8305
|
| 28194406 |
Lu M et al.:
Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome Signaling
Biomed Res Int
2017
2017
|
| 25947912 |
Kaneko YK et al.:
Diacylglycerol Signaling Pathway in Pancreatic beta-Cells: An Essential Role of Diacylglycerol Kinase in the Regulation of Insulin Secretion
Biol. Pharm. Bull.
2015
5: 669-673
|
| 19864425 |
Jedrychowski MP et al.:
Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling
J. Biol. Chem.
2010
285: 104-114
|
| 21818375 |
Esposito T et al.:
piR_015520 belongs to Piwi-associated RNAs regulates expression of the human melatonin receptor 1A gene
PLoS ONE
2011
6
|
| 26862218 |
Rameh LE et al.:
Phosphoinositide signalling in type 2 diabetes: a beta-cell perspective
Biochem. Soc. Trans.
2016
44: 293-298
|
| 27322064 |
Volkov P et al.:
A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits
PLoS ONE
2016
11
|
| 26199093 |
Sun H et al.:
Melatonin: a potential intervention for hepatic steatosis
Lipids Health Dis
2015
14: 75
|
| 25375650 |
Olsson AH et al.:
Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets
PLoS Genet.
2014
10
|
| 24603685 |
Dayeh T et al.:
Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion
PLoS Genet.
2014
10
|
| 9576906 |
Hogenesch JB et al.:
The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors
Proc. Natl. Acad. Sci. U.S.A.
1998
95: 5474-5479
|
| 15447895 |
Moloney F et al.:
Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus
Am. J. Clin. Nutr.
2004
80: 887-895
|
| 15126715 |
Eyjolfson V et al.:
Conjugated linoleic acid improves insulin sensitivity in young, sedentary humans
Med Sci Sports Exerc
2004
36: 814-820
|
| 15277146 |
Riserus U et al.:
Effects of cis-9,trans-11 conjugated linoleic acid supplementation on insulin sensitivity, lipid peroxidation, and proinflammatory markers in obese men
Am. J. Clin. Nutr.
2004
80: 279-283
|
| 19297053 |
Hong KW et al.:
RAPGEF1 gene variants associated with type 2 diabetes in the Korean population
Diabetes Res. Clin. Pract.
2009
84: 117-122
|
| 9887096 |
Mimura J et al.:
Identification of a novel mechanism of regulation of Ah (dioxin) receptor function
Genes Dev.
1999
13: 20-25
|
| 17890447 |
Haarmann-Stemmann T et al.:
Analysis of the transcriptional regulation and molecular function of the aryl hydrocarbon receptor repressor in human cell lines
Drug Metab. Dispos.
2007
35: 2262-2269
|
| 20878756 |
Arsenescu R et al.:
Role of the xenobiotic receptor in inflammatory bowel disease
Inflamm. Bowel Dis.
2011
17: 1149-1162
|
| 22761945 |
Jourdan C et al.:
Body fat free mass is associated with the serum metabolite profile in a population-based study
PLoS ONE
2012
7
|
| 11413087 |
Tian R et al.:
Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis
Circulation
2001
103: 2961-2966
|
| 28334807 |
Lee H et al.:
Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation
|
| 15184668 |
McClung JP et al.:
Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase
Proc. Natl. Acad. Sci. U.S.A.
2004
24: 8852-8857
|
| 18560803 |
Wang XD et al.:
Molecular mechanisms for hyperinsulinaemia induced by overproduction of selenium-dependent glutathione peroxidase-1 in mice
Diabetologia
2008
8: 1515-1524
|
| 23872396 |
Steinbrenner H et al.:
Interference of selenium and selenoproteins with the insulin-regulated carbohydrate and lipid metabolism
Free Radic. Biol. Med.
2013
65: 1538-1547
|
| 24439387 |
Claussnitzer M et al.:
Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms
Cell
2014
156: 343-358
|
| 28235194 |
Clemmensen C et al.:
Gut-Brain Cross-Talk in Metabolic Control
Cell
2017
168: 758-774
|
| 28275047 |
Muller TD et al.:
The New Biology and Pharmacology of Glucagon
Physiol. Rev.
2017
97: 721-766
|
| 27547419 |
Lu CW et al.:
High serum selenium levels are associated with increased risk for diabetes mellitus independent of central obesity and insulin resistance
BMJ Open Diabetes Res Care
2016
4
|
| 27983572 |
Jablonska E et al.:
The Effect of Selenium Supplementation on Glucose Homeostasis and the Expression of Genes Related to Glucose Metabolism
|
| 28414329 |
author information missing
article information missing
|
| 22426117 |
Krug S et al.:
The dynamic range of the human metabolome revealed by challenges
FASEB J.
2012
6: 2607-2619
|
| 23365373 |
Tous N et al.:
Dietary conjugated linoleic acid modify gene expression in liver, muscles, and fat tissues of finishing pigs
J. Anim. Sci.
2012
90: 340-342
|
| 20410232 |
Brons C et al.:
Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth-weight-dependent manner
J. Clin. Endocrinol. Metab.
2010
95: 3048-3056
|
| 23003921 |
Milagro FI et al.:
CLOCK, PER2 and BMAL1 DNA methylation: association with obesity and metabolic syndrome characteristics and monounsaturated fat intake
Chronobiol. Int.
2012
29: 1180-1194
|
| 25329159 |
Hoile SP et al.:
Supplementation with N-3 long-chain polyunsaturated fatty acids or olive oil in men and women with renal disease induces differential changes in the DNA methylation of FADS2 and ELOVL5 in peripheral blood mononuclear cells
PLoS ONE
2014
9
|
| 24322369 |
Burdge GC et al.:
Fatty acids and epigenetics
Curr Opin Clin Nutr Metab Care
2014
17: 156-161
|
| 26483700 |
Lettieri Barbato D et al.:
Dietary fat overload reprograms brown fat mitochondria
Front Physiol
2015
6: 272
|
| 25671565 |
Casas-Agustench P et al.:
Consumption of distinct dietary lipids during early pregnancy differentially modulates the expression of microRNAs in mothers and offspring
PLoS ONE
2015
10
|
| 28591636 |
Aichler M et al.:
N-acyl Taurines and Acylcarnitines Cause an Imbalance in Insulin Synthesis and Secretion Provoking beta Cell Dysfunction in Type 2 Diabetes
Cell Metab.
2017
25: 1334-1347
|
| 23159632 |
Waluk DP et al.:
N-Acyl taurines trigger insulin secretion by increasing calcium flux in pancreatic beta-cells
Biochem. Biophys. Res. Commun.
2013
430: 54-59
|
| 27244820 |
Adane AA et al.:
Diabetes in Pregnancy and Childhood Cognitive Development: A Systematic Review
|
| 28641781 |
Chorell E et al.:
Pregnancy to postpartum transition of serum metabolites in women with gestational diabetes
Metab. Clin. Exp.
2017
72: 27-36
|
| 27423999 |
Much D et al.:
Lactation is associated with altered metabolomic signatures in women with gestational diabetes
Diabetologia
2016
59: 2193-2202
|
| 28316001 |
Vacinova G et al.:
Associations of polymorphisms in the candidate genes for Alzheimers disease BIN1, CLU, CR1 and PICALM with gestational diabetes and impaired glucose tolerance
Mol. Biol. Rep.
2017
44: 227-231
|
| 28202837 |
Kasuga Y et al.:
Association of common polymorphisms with gestational diabetes mellitus in Japanese women: A case-control study
Endocr. J.
2017
64: 463-475
|
| 28314466 |
Dudzik D et al.:
GC-MS based Gestational Diabetes Mellitus longitudinal study: Identification of 2-and 3-hydroxybutyrate as potential prognostic biomarkers
|
| 3972965 |
et al.:
Effect of postpartum lactation on lipoprotein lipids and apoproteins
J. Clin. Endocrinol. Metab.
1985
60: 542-547
|
| 26595611 |
Gunderson EP et al.:
Lactation and Progression to Type 2 Diabetes Mellitus After Gestational Diabetes Mellitus: A Prospective Cohort Study
Ann. Intern. Med.
2015
163: 889-898
|
| 27338739 |
Allalou A et al.:
A Predictive Metabolic Signature for the Transition From Gestational Diabetes Mellitus to Type 2 Diabetes
Diabetes
2016
65: 2529-2539
|
| 26448018 |
Wang Y et al.:
Variants in Vitamin D Binding Protein Gene Are Associated With Gestational Diabetes Mellitus
Medicine (Baltimore)
2015
94: E1693
|
| 28367428 |
Rahimi N et al.:
Amino acid profiling in the gestational diabetes mellitus
J Diabetes Metab Disord
2017
16: 13
|
| 23761423 |
Huopio H et al.:
Association of risk variants for type 2 diabetes and hyperglycemia with gestational diabetes
Eur. J. Endocrinol.
2013
169: 291-297
|
| 25973943 |
Huerta-Chagoya A et al.:
Genetic determinants for gestational diabetes mellitus and related metabolic traits in Mexican women
PLoS ONE
2015
10
|
| 19002430 |
Cho YM et al.:
Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population
Diabetologia
2009
52: 253-261
|
| 27738328 |
Chen T et al.:
Genetic variants in PTPRD and risk of gestational diabetes mellitus
Oncotarget
2016
7
|
| 22396200 |
Bouchard L et al.:
Placental adiponectin gene DNA methylation levels are associated with mothers blood glucose concentration
Diabetes
2012
61: 1272-1280
|
| 28341729 |
Berridge MJ et al.:
Vitamin D deficiency and diabetes
Biochem. J.
2017
474: 1321-1332
|
| 18382804 |
Alfadda AA et al.:
Circulatory neutrophil chemokines in statin-treated diabetic patients
Saudi Med J
2008
29: 584-588
|
| 16436660 |
Gautier G et al.:
The class 6 semaphorin SEMA6A is induced by interferon-gamma and defines an activation status of langerhans cells observed in pathological situations
Am. J. Pathol.
2006
168: 453-465
|
| 24843127 |
Liew CW et al.:
Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic beta cells
Proc. Natl. Acad. Sci. U.S.A.
2014
111
|
| 19602578 |
Piquer S et al.:
Role of iduronate-2-sulfatase in glucose-stimulated insulin secretion by activation of exocytosis
Am. J. Physiol. Endocrinol. Metab.
2009
297: E793-E801
|
| 17244723 |
Zhang J et al.:
Alterations of the classic pathway of complement in adipose tissue of obesity and insulin resistance
Am. J. Physiol. Endocrinol. Metab.
2007
292
|
| 26649805 |
Horn S et al.:
Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During beta-Cell Mass Expansion In Vivo
Mol. Endocrinol.
2016
30: 133-143
|
| 27017379 |
Cao ZQ et al.:
The role of galectin-4 in physiology and diseases
Protein Cell
2016
7: 314-324
|
| 27440084 |
Blanco-Rojo R et al.:
Interaction of an S100A9 gene variant with saturated fat and carbohydrates to modulate insulin resistance in 3 populations of different ancestries
Am. J. Clin. Nutr.
2016
104: 508-517
|
| 15927886 |
Leukert N et al.:
Molecular basis of the complex formation between the two calcium-binding proteins S100A8 (MRP8) and S100A9 (MRP14)
Biol. Chem.
2005
386: 429-434
|
| 11124961 |
Nugent C et al.:
Arachidonic acid stimulates glucose uptake in 3T3-L1 adipocytes by increasing GLUT1 and GLUT4 levels at the plasma membrane. Evidence for involvement of lipoxygenase metabolites and peroxisome proliferator-activated receptor gamma
J. Biol. Chem.
2001
276: 9149-9157
|
| 22822112 |
Ortega FJ et al.:
Serum and urinary concentrations of calprotectin as markers of insulin resistance and type 2 diabetes
Eur. J. Endocrinol.
2012
167: 569-578
|
| 21738950 |
Catalan V et al.:
Increased levels of calprotectin in obesity are related to macrophage content: impact on inflammation and effect of weight loss
Mol. Med.
2011
17: 1157-1167
|
| 23055543 |
van Greevenbroek MM et al.:
Up-regulation of the complement system in subcutaneous adipocytes from nonobese, hypertriglyceridemic subjects is associated with adipocyte insulin resistance
J. Clin. Endocrinol. Metab.
2012
97: 4742-4752
|
| 18241861 |
Mwangi S et al.:
Glial cell line-derived neurotrophic factor increases beta-cell mass and improves glucose tolerance
Gastroenterology
2008
134: 727-737
|
| 20960036 |
Liu H et al.:
High glucose promotes cell proliferation and enhances GDNF and RET expression in pancreatic cancer cells
Mol. Cell. Biochem.
2011
347: 95-101
|
| 24778188 |
Gealekman O et al.:
Control of adipose tissue expandability in response to high fat diet by the insulin-like growth factor-binding protein-4
J. Biol. Chem.
2014
289
|
| 26974954 |
Watanabe J et al.:
Role of IGFBP7 in Diabetic Nephropathy: TGF-beta1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells
PLoS ONE
2016
11
|
| 25984973 |
Liu Y et al.:
Serum IGFBP7 levels associate with insulin resistance and the risk of metabolic syndrome in a Chinese population
Sci Rep
2015
5: 10227
|
| 23781310 |
Narayanan RP et al.:
IGFBP2 is a biomarker for predicting longitudinal deterioration in renal function in type 2 diabetes
Endocr Connect
2012
1: 95-102
|
| 20074524 |
Hedbacker K et al.:
Antidiabetic effects of IGFBP2, a leptin-regulated gene
Cell Metab.
2010
11: 11-22
|
| 22739111 |
Choi JW et al.:
Downregulation of fetuin-B and zinc-alpha2-glycoprotein is linked to impaired fatty acid metabolism in liver cells
Cell Physiol Biochem
2012
30: 295-306
|
| 19846739 |
Arafat AM et al.:
The role of insulin-like growth factor (IGF) binding protein-2 in the insulin-mediated decrease in IGF-I bioactivity
J. Clin. Endocrinol. Metab.
2009
94: 5093-5101
|
| 25645620 |
Baumeier C et al.:
Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice
Biochim. Biophys. Acta
2015
1851: 566-576
|
| 17192468 |
Yermen B et al.:
Pro-survival role of gelsolin in mouse beta-cells
Diabetes
2007
56: 80-87
|
| 25478578 |
Khatri N et al.:
Plasma gelsolin levels decrease in diabetic state and increase upon treatment with F-actin depolymerizing versions of gelsolin
J Diabetes Res
2014
2014
|
| 26788927 |
Pepaj M et al.:
Proteomic analysis of the INS-1E secretome identify novel vitamin D-regulated proteins
Diabetes Metab. Res. Rev.
2016
32: 514-521
|
| 28077579 |
Juan-Mateu J et al.:
Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival
J. Biol. Chem.
2017
292: 3466-3480
|
| 28135711 |
et al.:
Gelsolin Inhibits the Inflammatory Process Induced by LPS
Cell. Physiol. Biochem.
2017
41: 205-212
|
| 27224309 |
Wang YH et al.:
Cholesterol-Dependent Phase-Demixing in Lipid Bilayers as a Switch for the Activity of the Phosphoinositide-Binding Cytoskeletal Protein Gelsolin
Biochemistry
2016
55: 3361-3369
|
| 20810916 |
Bucki R et al.:
Plasma gelsolin modulates cellular response to sphingosine 1-phosphate
Am. J. Physiol.
2010
299
|
| 22951294 |
Campostrini N et al.:
Serum levels of the hepcidin-20 isoform in a large general population: the Val Borbera study
J Proteomics
2012
76: 28-35
|
| 24379355 |
Wang H et al.:
Hepcidin is directly regulated by insulin and plays an important role in iron overload in streptozotocin-induced diabetic rats
Diabetes
2014
63: 1506-1518
|
| 23024761 |
Vijayakumar A et al.:
Skeletal muscle growth hormone receptor signaling regulates basal, but not fasting-induced, lipid oxidation
PLoS ONE
2012
7
|
| 21555853 |
Wu Y et al.:
Growth hormone receptor regulates beta cell hyperplasia and glucose-stimulated insulin secretion in obese mice
J. Clin. Invest.
2011
121: 2422-2426
|
| 21325617 |
Guevara-Aguirre J et al.:
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans
Sci Transl Med
2011
3: 70RA13
|
| 19914217 |
Yang N et al.:
Growth hormone receptor targeting to lipid rafts requires extracellular subdomain 2
Biochem. Biophys. Res. Commun.
2010
391: 414-418
|
| 17537658 |
Strawbridge RJ et al.:
GHR exon 3 polymorphism: association with type 2 diabetes mellitus and metabolic disorder
Growth Horm. IGF Res.
2007
17: 392-398
|
| 28747974 |
Koh PO et al.:
Hyperglycemia decreases preoxiredoxin-2 expression in a middle cerebral artery occlusion model
Lab Anim Res
2017
33: 98-104
|
| 28123936 |
Stechemesser L et al.:
Metabolomic profiling identifies potential pathways involved in the interaction of iron homeostasis with glucose metabolism
Mol Metab
2016
6: 38-47
|
| 25834231 |
Sandoval DA et al.:
Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease
Physiol. Rev.
2015
95: 513-548
|
| 23353702 |
Pandey AV et al.:
NADPH P450 oxidoreductase: structure, function, and pathology of diseases
Pharmacol. Ther.
2013
138: 229-254
|
| 28791439 |
Gerst F et al.:
Metabolic crosstalk between fatty pancreas and fatty liver: effects on local inflammation and insulin secretion
|
| 28536464 |
Wagner R et al.:
The protective effect of human renal sinus fat on glomerular cells is reversed by the hepatokine fetuin-A
Sci Rep
2017
7: 2261
|
| 20225188 |
Heni M et al.:
Pancreatic fat is negatively associated with insulin secretion in individuals with impaired fasting glucose and/or impaired glucose tolerance: a nuclear magnetic resonance study
Diabetes Metab. Res. Rev.
2010
26: 200-205
|
| 24366423 |
Flint N et al.:
Effects of erythritol on endothelial function in patients with type 2 diabetes mellitus: a pilot study
Acta Diabetol
2014
51: 513-516
|
| 23746261 |
Zhao L et al.:
Methylerythritol phosphate pathway of isoprenoid biosynthesis
Annu. Rev. Biochem.
2013
82: 497-530
|
| 25271595 |
Hua X et al.:
Effects of L-carnitine, erythritol and betaine on pro-inflammatory markers in primary human corneal epithelial cells exposed to hyperosmotic stress
Curr. Eye Res.
2015
40: 657-667
|
| 23755276 |
Boesten DM et al.:
Multi-targeted mechanisms underlying the endothelial protective effects of the diabetic-safe sweetener erythritol
PLoS ONE
2013
8
|
| 26822086 |
Chen L et al.:
Plasma Metabonomic Profiling of Diabetic Retinopathy
Diabetes
2016
65: 1099-1108
|
| 27117004 |
Wolnerhanssen BK et al.:
Gut hormone secretion, gastric emptying, and glycemic responses to erythritol and xylitol in lean and obese subjects
Am. J. Physiol. Endocrinol. Metab.
2016
310
|
| 28484010 |
Hootman KC et al.:
Erythritol is a pentose-phosphate pathway metabolite and associated with adiposity gain in young adults
Proc. Natl. Acad. Sci. U.S.A.
2017
114
|
| 17873059 |
Fujimoto W et al.:
Dmbx1 is essential in agouti-related protein action
Proc. Natl. Acad. Sci. U.S.A.
2007
104
|
| 21965532 |
Wang H et al.:
The human histone chaperone sNASP interacts with linker and core histones through distinct mechanisms
Nucleic Acids Res.
2012
40: 660-669
|
| 27245224 |
Peiro C et al.:
Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway
Cardiovasc Diabetol
2016
15: 82
|
| 23884885 |
Menni C et al.:
Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach
Diabetes
2013
62: 4270-4276
|
| 23282133 |
Spegel P et al.:
Time-resolved metabolomics analysis of beta-cells implicates the pentose phosphate pathway in the control of insulin release
Biochem. J.
2013
450: 595-605
|
| 22847496 |
Huang M et al.:
Metabolomic analysis of pancreatic beta-cell insulin release in response to glucose
Islets
2012
4: 210-222
|
| 27620647 |
Overduin J et al.:
Failure of sucrose replacement with the non-nutritive sweetener erythritol to alter GLP-1 or PYY release or test meal size in lean or obese people
Appetite
2016
107: 596-603
|
| 17222174 |
Linster CL et al.:
Vitamin C. Biosynthesis, recycling and degradation in mammals
FEBS J.
2007
274: 1-22
|
| 28397877 |
de Mello VD et al.:
Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study
Sci Rep
2017
7: 46337
|
| 28533544 |
Piontek U et al.:
Sex-specific metabolic profiles of androgens and its main binding protein SHBG in a middle aged population without diabetes
Sci Rep
2017
7: 2235
|
| 25662186 |
Muller YL et al.:
A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians
Hum. Mol. Genet.
2015
24: 2985-2996
|
| 23876293 |
MacDonald MJ et al.:
Knockdown of both mitochondrial isocitrate dehydrogenase enzymes in pancreatic beta cells inhibits insulin secretion
Biochim. Biophys. Acta
2013
11: 5104-5111
|
| 25594249 |
Hasan NM et al.:
Mitochondrial malic enzyme 3 is important for insulin secretion in pancreatic beta-cells
Mol. Endocrinol.
2015
29: 396-410
|
| 25921846 |
de Mello VD et al.:
Markers of cholesterol metabolism as biomarkers in predicting diabetes in the Finnish Diabetes Prevention Study
Nutr Metab Cardiovasc Dis
2015
25: 635-642
|
| 28597074 |
Peddinti G et al.:
Early metabolic markers identify potential targets for the prevention of type 2 diabetes
|
| 28877454 |
Kalin S et al.:
A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function
Cell Metab.
2017
26: 475-492
|
| 27689005 |
Lerin C et al.:
Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism
Mol Metab
2016
5: 926-936
|
| 28585545 |
Axelsson AS et al.:
Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes
Nat Commun
2017
8: 15652
|
| 26116790 |
Gooding JR et al.:
Metabolomics applied to the pancreatic islet
Arch. Biochem. Biophys.
2016
589: 120-130
|
| 9862657 |
Munro IC et al.:
Erythritol: an interpretive summary of biochemical, metabolic, toxicological and clinical data
Food Chem. Toxicol.
1998
36: 1139-1174
|
| 27635141 |
de Cock P et al.:
Erythritol Is More Effective Than Xylitol and Sorbitol in Managing Oral Health Endpoints
Int J Dent
2016
2016
|
| 24741154 |
Chattopadhyay S et al.:
Artificial sweeteners - a review
J Food Sci Technol
2014
51: 611-621
|
| 24578795 |
Chung YS et al.:
Genotoxicity Assessment of Erythritol by Using Short-term Assay
Toxicol Res
2013
29: 249-255
|
| 21733844 |
Oberg F et al.:
Glycosylation increases the thermostability of human aquaporin 10 protein
J. Biol. Chem.
2011
286
|
| 26980210 |
Svingen GF et al.:
Prospective Associations of Systemic and Urinary Choline Metabolites with Incident Type 2 Diabetes
Clin. Chem.
2016
62: 755-765
|
| 26861782 |
Walford GA et al.:
Metabolite Profiles of Diabetes Incidence and Intervention Response in the Diabetes Prevention Program
Diabetes
2016
65: 1424-1433
|
| 26858359 |
Ejaz A et al.:
Dietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in Mice
Diabetes
2016
65: 902-912
|
| 26850693 |
Day CR et al.:
Betaine chemistry, roles, and potential use in liver disease
Biochim. Biophys. Acta
2016
1860: 1098-1106
|
| 25013088 |
McEntyre CJ et al.:
Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period
Ann. Clin. Biochem.
2015
52: 352-360
|
| 25675436 |
Okabayashi S et al.:
Diabetes mellitus accelerates Abeta pathology in brain accompanied by enhanced GAbeta generation in nonhuman primates
PLoS ONE
2015
10
|
| 26043887 |
Vukovic I et al.:
The missing link - likely pathogenetic role of GM3 and other gangliosides in the development of diabetic nephropathy
Kidney Blood Press. Res.
2015
40: 306-314
|
| 28747646 |
Zeng H et al.:
Metabolic Biomarkers for Prognostic Prediction of Pre-diabetes: results from a longitudinal cohort study
Sci Rep
2017
7: 6575
|
| 20724529 |
Kathirvel E et al.:
Betaine improves nonalcoholic fatty liver and associated hepatic insulin resistance: a potential mechanism for hepatoprotection by betaine
Am. J. Physiol. Gastrointest. Liver Physiol.
2010
299
|
| 17702954 |
Song Z et al.:
Involvement of AMP-activated protein kinase in beneficial effects of betaine on high-sucrose diet-induced hepatic steatosis
Am. J. Physiol. Gastrointest. Liver Physiol.
2007
293: G894-G902
|
| 23884887 |
Haeusler RA et al.:
Human insulin resistance is associated with increased plasma levels of 12alpha-hydroxylated bile acids
Diabetes
2013
62: 4184-4191
|
| 25456122 |
Chimerel C et al.:
Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells
Cell Rep
2014
9: 1202-1208
|
| 24760535 |
Sonne DP et al.:
Bile acid sequestrants in type 2 diabetes: potential effects on GLP1 secretion
Eur J Endocrinol
2014
171: R47-R65
|
| 24623198 |
Hansen M et al.:
Bile acid sequestrants: glucose-lowering mechanisms and efficacy in type 2 diabetes
Curr. Diab. Rep.
2014
14: 482
|
| 18381287 |
Ronnebaum SM et al.:
Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism
J. Biol. Chem.
2008
283
|
| 23085009 |
Veret J et al.:
Role of palmitate-induced sphingoid base-1-phosphate biosynthesis in INS-1 beta-cell survival
Biochim. Biophys. Acta
2013
1831: 251-262
|
| 26450397 |
Giskeodegard GF et al.:
Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation
Sci Rep
2015
5: 14843
|
| 23936331 |
Schartum-Hansen H et al.:
Assessment of urinary betaine as a marker of diabetes mellitus in cardiovascular patients
PLoS ONE
2013
8
|
| 23363978 |
Lindtner C et al.:
Binge drinking induces whole-body insulin resistance by impairing hypothalamic insulin action
Sci Transl Med
2013
5: 170ra14
|
| 27406814 |
Fall T et al.:
Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes
Diabetologia
2016
59: 2114-2124
|
| 28810182 |
Speckmann B et al.:
Selenium increases hepatic DNA methylation and modulates one-carbon metabolism in the liver of mice
J. Nutr. Biochem.
2017
48: 112-119
|
| 28973848 |
Loizides-Mangold U et al.:
Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro
Proc. Natl. Acad. Sci. U.S.A.
2017
114
|
| 28821636 |
Isherwood CM et al.:
Twenty-four-hour rhythmicity of circulating metabolites: effect of body mass and type 2 diabetes
FASEB J.
2017
31: 5557-5567
|
| 28872611 |
Bashir KMI et al.:
Clinical and Physiological Perspectives of beta-Glucans: The Past, Present, and Future
|
| 28191525 |
Tomkin GH et al.:
Obesity diabetes and the role of bile acids in metabolism
J Transl Int Med
2016
4: 73-80
|
| 23378610 |
Xie W et al.:
Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes
Diabetes
2013
62: 2141-2150
|
| 28930162 |
Ingenbleek Y et al.:
Lean Body Mass Harbors Sensing Mechanisms that Allow Safeguarding of Methionine Homeostasis
|
| 12730242 |
Gual P et al.:
Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes
J. Biol. Chem.
2003
278
|
| 27249024 |
Kim YJ et al.:
Association of Metabolites with Obesity and Type 2 Diabetes Based on FTO Genotype
PLoS ONE
2016
11
|
| 25952934 |
Seibert R et al.:
Relationship between insulin resistance and amino acids in women and men
|
| 25795213 |
Magnusson M et al.:
Dimethylglycine Deficiency and the Development of Diabetes
Diabetes
2015
64: 3010-3016
|
| 26605869 |
Dujic T et al.:
Organic cation transporter 1 variants and gastrointestinal side effects of metformin in patients with Type 2 diabetes
Diabet. Med.
2016
33: 511-514
|
| 27816442 |
Chen Q et al.:
Metformin impairs systemic bile acid homeostasis through regulating SIRT1 protein levels
Biochim. Biophys. Acta
2017
1864: 101-112
|
| 28530702 |
Wu H et al.:
Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug
Nat. Med.
2017
23: 850-858
|
| 27999002 |
de la Cuesta-Zuluaga J et al.:
Metformin Is Associated With Higher Relative Abundance of Mucin-Degrading Akkermansia muciniphila and Several Short-Chain Fatty Acid-Producing Microbiota in the Gut
Diabetes Care
2017
40: 54-62
|
| 28804275 |
Liu J et al.:
Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study
Metabolomics
2017
13: 104
|
| 27741291 |
Fukai K et al.:
Metabolic Profiling of Total Physical Activity and Sedentary Behavior in Community-Dwelling Men
PLoS ONE
2016
11
|
| 28208582 |
Luciano-Mateo F et al.:
Nutrients in Energy and One-Carbon Metabolism: Learning from Metformin Users
|
| 4567003 |
author information missing
The glucose-alanine cycle
Metab. Clin. Exp.
1973
22: 179-207
|
| 28942964 |
Kim HI et al.:
Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport
Am. J. Hum. Genet.
2017
101: 489-502
|
| 22735389 |
Tarasova L et al.:
Association of genetic variation in the organic cation transporters OCT1, OCT2 and multidrug and toxin extrusion 1 transporter protein genes with the gastrointestinal side effects and lower BMI in metformin-treated type 2 diabetes patients
Pharmacogenet. Genomics
2012
22: 659-666
|
| 27618090 |
Li X et al.:
Short- and Long-Term Effects of Wholegrain Oat Intake on Weight Management and Glucolipid Metabolism in Overweight Type-2 Diabetics: A Randomized Control Trial
|
| 29129983 |
Grundy MML et al.:
The impact of oat structure and beta-glucan on in vitro lipid digestion
J Funct Foods
2017
38: 378-388
|
| 9925123 |
Bourdon I et al.:
Postprandial lipid, glucose, insulin, and cholecystokinin responses in men fed barley pasta enriched with beta-glucan
Am. J. Clin. Nutr.
1999
69: 55-63
|
| 12080401 |
Jenkins AL et al.:
Depression of the glycemic index by high levels of beta-glucan fiber in two functional foods tested in type 2 diabetes
Eur J Clin Nutr
2002
56: 622-628
|
| 16054549 |
Tapola N et al.:
Glycemic responses of oat bran products in type 2 diabetic patients
Nutr Metab Cardiovasc Dis
2005
15: 255-261
|
| 17151593 |
Makelainen H et al.:
The effect of beta-glucan on the glycemic and insulin index
Eur J Clin Nutr
2007
61: 779-785
|
| 17426742 |
Granfeldt Y et al.:
Muesli with 4 g oat beta-glucans lowers glucose and insulin responses after a bread meal in healthy subjects
Eur J Clin Nutr
2008
62: 600-607
|
| 19700035 |
Thondre PS et al.:
High-molecular-weight barley beta-glucan in chapatis (unleavened Indian flatbread) lowers glycemic index
Nutr Res
2009
29: 480-486
|
| 19781120 |
Cugnet-Anceau C et al.:
A controlled study of consumption of beta-glucan-enriched soups for 2 months by type 2 diabetic free-living subjects
Br. J. Nutr.
2010
103: 422-428
|
| 25948672 |
Wittenbecher C et al.:
Amino acids, lipid metabolites, and ferritin as potential mediators linking red meat consumption to type 2 diabetes
Am. J. Clin. Nutr.
2015
101: 1241-1250
|
| 20423748 |
Kalhan SC et al.:
Plasma metabolomic profile in nonalcoholic fatty liver disease
Metab. Clin. Exp.
2011
60: 404-413
|
| 20111019 |
Mihalik SJ et al.:
Increased levels of plasma acylcarnitines in obesity and type 2 diabetes and identification of a marker of glucolipotoxicity
Obesity (Silver Spring)
2010
18: 1695-1700
|
| 20560578 |
Kim JY et al.:
Metabolic profiling of plasma in overweight/obese and lean men using ultra performance liquid chromatography and Q-TOF mass spectrometry (UPLC-Q-TOF MS)
J. Proteome Res.
2010
9: 4368-4375
|
| 28758372 |
Menni C et al.:
Metabolomic Profiling of Long-Term Weight Change: Role of Oxidative Stress and Urate Levels in Weight Gain
Obesity (Silver Spring)
2017
25: 1618-1624
|
| 26085512 |
Butte NF et al.:
Global metabolomic profiling targeting childhood obesity in the Hispanic population
Am. J. Clin. Nutr.
2015
102: 256-267
|
| 28973971 |
Montandon SA et al.:
Effects of Antidiabetic Drugs on Gut Microbiota Composition
|
| 29082264 |
Sohail MU et al.:
Role of the Gastrointestinal Tract Microbiome in the Pathophysiology of Diabetes Mellitus
J Diabetes Res
2017
2017
|
| 22752055 |
Montonen J et al.:
Body iron stores and risk of type 2 diabetes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study
Diabetologia
2012
55: 2613-2621
|
| 20980488 |
Kroger J et al.:
Erythrocyte membrane phospholipid fatty acids, desaturase activity, and dietary fatty acids in relation to risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study
Am. J. Clin. Nutr.
2011
93: 127-142
|
| 20016880 |
Xu J et al.:
Identification of biochemical changes in lactovegetarian urine using 1H NMR spectroscopy and pattern recognition
Anal Bioanal Chem
2010
396: 1451-1463
|
| 25971927 |
Byrne CS et al.:
The role of short chain fatty acids in appetite regulation and energy homeostasis
Int J Obes (Lond)
2015
39: 1331-1338
|
| 25116686 |
Laerke HN et al.:
Effect of beta-glucan supplementation on acute postprandial changes in fatty acid profile of lymph and serum in pigs
Int J Mol Sci
2014
15
|
| 19716281 |
Drozdowski LA et al.:
Beta-glucan extracts inhibit the in vitro intestinal uptake of long-chain fatty acids and cholesterol and down-regulate genes involved in lipogenesis and lipid transport in rats
J. Nutr. Biochem.
2010
21: 695-701
|
| 24223616 |
Al-Malki AL et al.:
Oat Protects against Diabetic Nephropathy in Rats via Attenuating Advanced Glycation End Products and Nuclear Factor Kappa B
Evid Based Complement Alternat Med
2013
2013
|
| 13577796 |
et al.:
Liver glucosyl oligosaccharides and glycogen; effects of starvation, glucose feeding and insulin
Nature
1958
182: 240-242
|
| 5914337 |
et al.:
Metabolism of glycogen and maltosyl oligosaccharides
Biochim. Biophys. Acta
1966
117: 255-257
|
| 26278983 |
Zeqiraj E et al.:
Getting a handle on glycogen synthase - Its interaction with glycogenin
Mol. Aspects Med.
2015
46: 63-69
|
| 12055180 |
Zhang Y et al.:
Identification, tissue expression, and functional characterization of Otx3, a novel member of the Otx family
J. Biol. Chem.
2002
277
|
| 28770335 |
Chukwuma CI et al.:
Erythritol reduces small intestinal glucose absorption, increases muscle glucose uptake, improves glucose metabolic enzymes activities and increases expression of Glut-4 and IRS-1 in type 2 diabetic rats
|
| 28940103 |
Liew G et al.:
Metabolomics of Diabetic Retinopathy
Curr. Diab. Rep.
2017
17: 102
|
| 27778251 |
Ting DS et al.:
Biomarkers of Diabetic Retinopathy
Curr. Diab. Rep.
2016
16: 125
|
| 29355425 |
de Cock P et al.:
Erythritol Functional Roles in Oral-Systemic Health
Adv. Dent. Res.
2018
29: 104-109
|
| 12207496 |
Yokozawa T et al.:
Erythritol attenuates the diabetic oxidative stress through modulating glucose metabolism and lipid peroxidation in streptozotocin-induced diabetic rats
J. Agric. Food Chem.
2002
50: 5485-5489
|
| 8933647 |
Ishikawa M et al.:
Effects of oral administration of erythritol on patients with diabetes
Regul. Toxicol. Pharmacol.
1996
24: S303-S308
|
| 8933644 |
Bornet FR et al.:
Plasma and urine kinetics of erythritol after oral ingestion by healthy humans
Regul. Toxicol. Pharmacol.
1996
24: S280-S285
|
| 29361825 |
Wen H et al.:
Erythritol Attenuates Postprandial Blood Glucose by Inhibiting alpha-Glucosidase
J. Agric. Food Chem.
2018
66: 1401-1407
|
| 23633210 |
Xu F et al.:
Metabolic signature shift in type 2 diabetes mellitus revealed by mass spectrometry-based metabolomics
J. Clin. Endocrinol. Metab.
2013
98
|
| 15466941 |
Bouche C et al.:
The cellular fate of glucose and its relevance in type 2 diabetes
Endocr. Rev.
2004
25: 807-830
|
| 19632091 |
den Hartog GJ et al.:
Erythritol is a sweet antioxidant
Nutrition
2010
26: 449-458
|
| 29281744 |
Lu Q et al.:
Antidiabetic cataract effects of GbE, rutin and quercetin are mediated by the inhibition of oxidative stress and polyol pathway
|
| 20011628 |
Isai M et al.:
Prevention of selenite-induced cataractogenesis by rutin in Wistar rats
Mol. Vis.
2009
15: 2570-2577
|
| 2253350 |
Roboz J et al.:
Polyol concentrations in serum during hemodialysis
Clin. Chem.
1990
36: 2082-2086
|
| 19531645 |
Hue L et al.:
The Randle cycle revisited: a new head for an old hat
Am. J. Physiol. Endocrinol. Metab.
2009
297: E578-E591
|
| 20929994 |
Sekhar RV et al.:
Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine
Diabetes Care
2011
34: 162-167
|
| 24961547 |
Jain SK et al.:
Vitamin D and L-cysteine levels correlate positively with GSH and negatively with insulin resistance levels in the blood of type 2 diabetic patients
Eur J Clin Nutr
2014
68: 1148-1153
|
| 26778482 |
Jain SK et al.:
L-cysteine supplementation upregulates glutathione (GSH) and vitamin D binding protein (VDBP) in hepatocytes cultured in high glucose and in vivo in liver, and increases blood levels of GSH, VDBP, and 25-hydroxy-vitamin D in Zucker diabetic fatty rats
Mol Nutr Food Res
2016
60: 1090-1098
|
| 22108094 |
Elshorbagy AK et al.:
Cysteine and obesity: consistency of the evidence across epidemiologic, animal and cellular studies
Curr Opin Clin Nutr Metab Care
2012
15: 49-57
|
| 18377884 |
Liu Z et al.:
The antidiabetic effects of cysteinyl metformin, a newly synthesized agent, in alloxan- and streptozocin-induced diabetic rats
Chem. Biol. Interact.
2008
173: 68-75
|
| 7925706 |
Ortwerth BJ et al.:
Ascorbic acid glycation: the reactions of L-threose in lens tissue
Exp. Eye Res.
1994
58: 665-674
|
| 28842639 |
Santos GC et al.:
Metabolomic Analysis Reveals Vitamin D-induced Decrease in Polyol Pathway and Subtle Modulation of Glycolysis in HEK293T Cells
Sci Rep
2017
7: 9510
|
| 26896333 |
Jagdale AD et al.:
Strong inhibition of the polyol pathway diverts glucose flux to protein glycation leading to rapid establishment of secondary complications in diabetes mellitus
J. Diabetes Complicat.
2016
30: 398-405
|
| 27197688 |
Gallagher EJ et al.:
Polyol accumulation in muscle and liver in a mouse model of type 2 diabetes
J. Diabetes Complicat.
2016
30: 999-1007
|
| 18245813 |
Dongiovanni P et al.:
Iron depletion by deferoxamine up-regulates glucose uptake and insulin signaling in hepatoma cells and in rat liver
Am. J. Pathol.
2008
172: 738-747
|
| 23578384 |
Dongiovanni P et al.:
Dietary iron overload induces visceral adipose tissue insulin resistance
Am. J. Pathol.
2013
182: 2254-2263
|
| 25729473 |
Aigner E et al.:
Dysregulation of iron and copper homeostasis in nonalcoholic fatty liver
World J Hepatol
2015
7: 177-188
|
| 28706239 |
Moreno-Navarrete JM et al.:
Increased adipose tissue heme levels and exportation are associated with altered systemic glucose metabolism
Sci Rep
2017
7: 5305
|
| 26301810 |
et al.:
Adipocyte iron regulates leptin and food intake
J. Clin. Invest.
2015
125: 3681-3691
|
| 22582044 |
Tang WH et al.:
Aldose reductase, oxidative stress, and diabetic mellitus
Front Pharmacol
2012
3: 87
|
| 24657938 |
Carter R et al.:
Non-alcoholic fatty pancreas disease pathogenesis: a role for developmental programming and altered circadian rhythms
PLoS ONE
2014
9
|
| 22460952 |
Cho H et al.:
Regulation of circadian behaviour and metabolism by REV-ERB-alpha and REV-ERB-beta
Nature
2012
485: 123-127
|
| 15482345 |
Piperno A et al.:
Effects of venesections and restricted diet in patients with the insulin-resistance hepatic iron overload syndrome
Liver Int.
2004
24: 471-476
|
| 29234017 |
Carayol J et al.:
Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator
Nat Commun
2017
8: 2084
|
| 28271632 |
Morrell A et al.:
The role of insufficient copper in lipid synthesis and fatty-liver disease
IUBMB Life
2017
69: 263-270
|
| 21425984 |
Hatcher HC et al.:
Synthetic and natural iron chelators: therapeutic potential and clinical use
Future Med Chem
2009
1: 1643-1670
|
| 26033743 |
Tallino S et al.:
Nutrigenomics analysis reveals that copper deficiency and dietary sucrose up-regulate inflammation, fibrosis and lipogenic pathways in a mature rat model of nonalcoholic fatty liver disease
J. Nutr. Biochem.
2015
26: 996-1006
|
| 29057834 |
Antonucci L et al.:
Non-Alcoholic Fatty Liver Disease and Nutritional Implications: Special Focus on Copper
|
| 9821181 |
Miller GD et al.:
Copper deficiency and arachidonic acid enhance insulin secretion in isolated pancreatic islets from lean (FaFa) Zucker rats
Pancreas
1998
17: 390-396
|
| 24361124 |
Vecchi C et al.:
Gluconeogenic signals regulate iron homeostasis via hepcidin in mice
Gastroenterology
2014
146: 1060-1069
|
| 17429063 |
Swaminathan S et al.:
The role of iron in diabetes and its complications
Diabetes Care
2007
30: 1926-1933
|
| 25817068 |
Schneider C et al.:
Degradation of Curcumin: From Mechanism to Biological Implications
J. Agric. Food Chem.
2015
63: 7606-7614
|
| 21525193 |
Sevastianova K et al.:
Genetic variation in PNPLA3 (adiponutrin) confers sensitivity to weight loss-induced decrease in liver fat in humans
Am. J. Clin. Nutr.
2011
94: 104-111
|
| 27711063 |
Schroeder BO et al.:
Signals from the gut microbiota to distant organs in physiology and disease
Nat. Med.
2016
22: 1079-1089
|
| 29118444 |
Iannuzzi C et al.:
Vanillin Affects Amyloid Aggregation and Non-Enzymatic Glycation in Human Insulin
Sci Rep
2017
7: 15086
|
| 29445185 |
Chaudhary K et al.:
Iron Overload Accelerates the Progression of Diabetic Retinopathy in Association with Increased Retinal Renin Expression
Sci Rep
2018
8: 3025
|
| 29097552 |
Edwards RL et al.:
The anti-inflammatory activity of curcumin is mediated by its oxidative metabolites
J. Biol. Chem.
2017
292
|
| 9631292 |
Dodson G et al.:
The role of assembly in insulins biosynthesis
Curr. Opin. Struct. Biol.
1998
8: 189-194
|
| 29415457 |
Fukunaka A et al.:
Role of Zinc Homeostasis in the Pathogenesis of Diabetes and Obesity
|
| 16866381 |
Hong DP et al.:
Fibrillation of human insulin A and B chains
Biochemistry
2006
45: 9342-9353
|
| 24462809 |
Nagase T et al.:
Insulin-derived amyloidosis and poor glycemic control: a case series
Am. J. Med.
2014
127: 450-454
|
| 25593849 |
Gupta Y et al.:
Insulin-derived amyloidosis
Indian J Endocrinol Metab
2015
19: 174-177
|
| 11099867 |
Boyd AC et al.:
Impaired ability of glycated insulin to regulate plasma glucose and stimulate glucose transport and metabolism in mouse abdominal muscle
Biochim. Biophys. Acta
2000
1523: 128-134
|
| 21819598 |
Oliveira LM et al.:
Insulin glycation by methylglyoxal results in native-like aggregation and inhibition of fibril formation
BMC Biochem.
2011
12: 41
|
| 26519138 |
Iannuzzi C et al.:
D-ribose-glycation of insulin prevents amyloid aggregation and produces cytotoxic adducts
Biochim. Biophys. Acta
2016
1862: 93-104
|
| 19864624 |
Ivanova MI et al.:
Molecular basis for insulin fibril assembly
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 12716753 |
Facchini FS et al.:
A low-iron-available, polyphenol-enriched, carbohydrate-restricted diet to slow progression of diabetic nephropathy
Diabetes
2003
52: 1204-1209
|
| 29083385 |
Misra G et al.:
Iron Profile and Glycaemic Control in Patients with Type 2 Diabetes Mellitus
|
| 22579683 |
Sparks S et al.:
Curcumin modulates the self-assembly of the islet amyloid polypeptide by disassembling alpha-helix
Biochem. Biophys. Res. Commun.
2012
422: 551-555
|
| 26587568 |
Pithadia AS et al.:
Influence of a curcumin derivative on hIAPP aggregation in the absence and presence of lipid membranes
Chem. Commun. (Camb.)
2016
52: 942-945
|
| 28708089 |
Uebanso T et al.:
Effects of Consuming Xylitol on Gut Microbiota and Lipid Metabolism in Mice
|
| 29539432 |
Fujisaka S et al.:
Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites
Cell Rep
2018
22: 3072-3086
|
| 26649317 |
Pithadia A et al.:
Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives
J Diabetes Res
2016
2016
|
| 29204886 |
Sasahara K et al.:
Membrane-mediated amyloid deposition of human islet amyloid polypeptide
Biophys Rev
2018
10: 453-462
|
| 29043504 |
Bhowmick DC et al.:
The Molecular Physiopathogenesis of Islet Amyloidosis
Handb Exp Pharmacol
2018
245: 271-312
|
| 29373534 |
Du J et al.:
Betaine Supplementation Enhances Lipid Metabolism and Improves Insulin Resistance in Mice Fed a High-Fat Diet
|
| 22206987 |
Cao P et al.:
Sensitivity of amyloid formation by human islet amyloid polypeptide to mutations at residue 20
J. Mol. Biol.
2012
421: 282-295
|
| 23995676 |
Rabiee A et al.:
How curcumin affords effective protection against amyloid fibrillation in insulin
Food Funct
2013
4: 1474-1480
|
| 21753902 |
Stefek M et al.:
Natural flavonoids as potential multifunctional agents in prevention of diabetic cataract
Interdiscip Toxicol
2011
4: 69-77
|
| 24843182 |
Dodda D et al.:
Plants used in the management of diabetic complications
Indian J Pharm Sci
2014
76: 97-106
|
| 28860833 |
Dorcely B et al.:
Novel biomarkers for prediabetes, diabetes, and associated complications
Diabetes Metab Syndr Obes
2017
10: 345-361
|
| 22995213 |
Lu SC et al.:
Glutathione synthesis
Biochim. Biophys. Acta
2013
1830: 3143-3153
|
| 22896743 |
Newsholme P et al.:
Nutritional regulation of insulin secretion: implications for diabetes
Clin Biochem Rev
2012
33: 35-47
|
| 23945722 |
Aune D et al.:
Dairy products and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis of cohort studies
Am. J. Clin. Nutr.
2013
98: 1066-1083
|
| 8772735 |
Sakagashira S et al.:
Missense mutation of amylin gene (S20G) in Japanese NIDDM patients
Diabetes
1996
45: 1279-1281
|
| 24843500 |
Morita S et al.:
Progressive deterioration of insulin secretion in Japanese type 2 diabetic patients in comparison with those who carry the S20G mutation of the islet amyloid polypeptide gene: A long-term follow-up study
J Diabetes Investig
2011
2: 287-292
|
| 11318791 |
Lee SC et al.:
The islet amyloid polypeptide (amylin) gene S20G mutation in Chinese subjects: evidence for associations with type 2 diabetes and cholesterol levels
Clin. Endocrinol. (Oxf)
2001
54: 541-546
|
| 29437822 |
Li X et al.:
Elevated Serum Xanthine Oxidase Activity Is Associated With the Development of Type 2 Diabetes: A Prospective Cohort Study
Diabetes Care
2018
41: 884-890
|
| 24065788 |
Johnson RJ et al.:
Sugar, uric acid, and the etiology of diabetes and obesity
Diabetes
2013
62: 3307-3315
|
| 26411681 |
Gooding JR et al.:
Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism
Cell Rep
2015
13: 157-167
|
| 28403945 |
Washio KW et al.:
Xanthine oxidoreductase activity is correlated with insulin resistance and subclinical inflammation in young humans
Metab. Clin. Exp.
2017
70: 51-56
|
| 29619007 |
Tassone EJ et al.:
Uric Acid Impairs Insulin Signaling by Promoting Enpp1 Binding to Insulin Receptor in Human Umbilical Vein Endothelial Cells
Front Endocrinol (Lausanne)
2018
9: 98
|
| 27702941 |
Cornelis MC et al.:
Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior
Hum. Mol. Genet.
2016
25: 5472-5482
|
| 29643318 |
Furuhashi M et al.:
Plasma Xanthine Oxidoreductase Activity as a Novel Biomarker of Metabolic Disorders in a General Population
|
| 29601913 |
Lee SG et al.:
Fasting serum amino acids concentration is associated with insulin resistance and pro-inflammatory cytokines
Diabetes Res. Clin. Pract.
2018
140: 107-117
|
| 24855629 |
Sadasivan SK et al.:
Modulation of de novo purine biosynthesis leads to activation of AMPK and results in improved glucose handling and insulin sensitivity
J Diabetes Metab Disord
2014
13: 51
|
| 26389676 |
author information missing
Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional beta cells
J. Clin. Invest.
2015
125: 3847-3860
|
| 21266332 |
Dai XQ et al.:
SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans
Diabetes
2011
60: 838-847
|
| 29849027 |
Sweetlove LJ et al.:
The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation
Nat Commun
2018
9: 2136
|
| 712834 |
et al.:
Uncoupling of the catalytic activity and the polymerization of beef liver glutamate dehydrogenase
J. Mol. Biol.
1978
124: 291-295
|
| 20798350 |
Li H et al.:
Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 25687571 |
Boutchueng-Djidjou M et al.:
The last enzyme of the de novo purine synthesis pathway 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) plays a central role in insulin signaling and the Golgi/endosomes protein network
Mol. Cell Proteomics
2015
14: 1079-1092
|
| 25338814 |
Pirkmajer S et al.:
Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation
Diabetes
2015
64: 360-369
|
| 18243136 |
Stanojevic V et al.:
Cytosolic adenylate kinases regulate K-ATP channel activity in human beta-cells
Biochem. Biophys. Res. Commun.
2008
368: 614-619
|
| 18971329 |
Cha SH et al.:
Differential effects of central fructose and glucose on hypothalamic malonyl-CoA and food intake
Proc. Natl. Acad. Sci. U.S.A.
2008
105
|
| 22287021 |
Gloria-Bottini F et al.:
Adenylate kinase genetic polymorphism and spontaneous abortion
Am. J. Hum. Biol.
2012
24: 186-188
|
| 18032600 |
Wolfgang MJ et al.:
Regulation of hypothalamic malonyl-CoA by central glucose and leptin
Proc. Natl. Acad. Sci. U.S.A.
2007
104
|
| 23988346 |
Gao S et al.:
Hypothalamic malonyl-CoA and the control of food intake
Physiol. Behav.
2013
122: 17-24
|
| 21108053 |
Safranow K et al.:
AMPD1 gene mutations are associated with obesity and diabetes in Polish patients with cardiovascular diseases
J. Appl. Genet.
2011
52: 67-76
|
| 25887856 |
Tandelilin AA et al.:
AMPD1 regulates mTORC1-p70 S6 kinase axis in the control of insulin sensitivity in skeletal muscle
BMC Endocr Disord
2015
15: 11
|
| 28765812 |
Hudoyo AW et al.:
Role of AMPD2 in impaired glucose tolerance induced by high fructose diet
Mol Genet Metab Rep
2017
13: 23-29
|
| 27034960 |
Vindeirinho J et al.:
The Adenosinergic System in Diabetic Retinopathy
J Diabetes Res
2016
2016
|
| 25522227 |
Cieslak M et al.:
Purinergic signaling in the pancreas and the therapeutic potential of ecto-nucleotidases in diabetes
Acta Biochim. Pol.
2014
61: 655-662
|
| 23546842 |
Burnstock G et al.:
Purinergic signalling and diabetes
Purinergic Signal.
2013
9: 307-324
|
| 25308443 |
Chiu GS et al.:
Modulation of neuroimmunity by adenosine and its receptors: metabolism to mental illness
Metab. Clin. Exp.
2014
63: 1491-1498
|
| 24453844 |
Khemka VK et al.:
Raised serum adenosine deaminase level in nonobese type 2 diabetes mellitus
ScientificWorldJournal
2013
2013
|
| 24265070 |
Burnstock G et al.:
Purinergic signalling in endocrine organs
Purinergic Signal.
2014
10: 189-231
|
| 25511531 |
Cheng J et al.:
AMPD1: a novel therapeutic target for reversing insulin resistance
BMC Endocr Disord
2014
14: 96
|
| 19738938 |
Kocbuch K et al.:
Effect of insulin and glucose on adenosine metabolizing enzymes in human B lymphocytes
Acta Biochim. Pol.
2009
56: 439-446
|
| 21738897 |
Lee JG et al.:
Changes in Adenosine Deaminase Activity in Patients with Type 2 Diabetes Mellitus and Effect of DPP-4 Inhibitor Treatment on ADA Activity
Diabetes Metab J
2011
35: 149-158
|
| 29962948 |
Pastor-Anglada M et al.:
Who Is Who in Adenosine Transport
Front Pharmacol
2018
9: 627
|
| 28654087 |
Wu L et al.:
Caffeine inhibits hypothalamic A1R to excite oxytocin neuron and ameliorate dietary obesity in mice
Nat Commun
2017
8: 15904
|
| 26413467 |
Adamson SE et al. et al.:
Pannexin 1 is required for full activation of insulin-stimulated glucose uptake in adipocytes
Mol Metab
2015
4: 610-618
|
| 29619754 |
Burnstock G et al.:
The involvement of purinergic signalling in obesity
Purinergic Signal.
2018
14: 97-108
|
| 18199690 |
Goldfine ID et al.:
The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities
Endocr. Rev.
2008
29: 62-75
|
| 16186408 |
Bacci S et al. et al.:
The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction
Diabetes
2005
54: 3021-3025
|
| 18071025 |
McAteer JB et al.:
The ENPP1 K121Q polymorphism is associated with type 2 diabetes in European populations: evidence from an updated meta-analysis in 42,042 subjects
Diabetes
2008
57: 1125-1130
|
| 16025115 |
Meyre D et al. et al.:
Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes
Nat. Genet.
2005
37: 863-867
|
| 26727116 |
Reeves VL et al.:
Serum Autotaxin/ENPP2 correlates with insulin resistance in older humans with obesity
Obesity (Silver Spring)
2015
23: 2371-2376
|
| 24969110 |
Nishimura S et al. et al.:
ENPP2 contributes to adipose tissue expansion and insulin resistance in diet-induced obesity
Diabetes
2014
63: 4154-4164
|
| 28898552 |
Gorelik A et al.:
A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP5
FEBS J.
2017
284: 3718-3726
|
| 26888014 |
Morita J et al. et al.:
Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
Sci Rep
2016
6: 20995
|
| 30072447 |
D'Souza K et al. et al.:
Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism
J. Lipid Res.
2018
59: 1805-1817
|
| 16125936 |
Stefan C et al.:
NPP-type ectophosphodiesterases: unity in diversity
Trends Biochem. Sci.
2005
30: 542-550
|
| 19017751 |
Moore AF et al.:
The association of ENPP1 K121Q with diabetes incidence is abolished by lifestyle modification in the diabetes prevention program
J. Clin. Endocrinol. Metab.
2009
94: 449-455
|
| 18950909 |
De Cosmo S et al. et al.:
Association of the Q121 variant of ENPP1 gene with decreased kidney function among patients with type 2 diabetes
Am. J. Kidney Dis.
2009
53: 273-280
|
| 19656007 |
Tanyolac S et al.:
Genetic variants of the ENPP1/PC-1 gene are associated with hypertriglyceridemia in male subjects
Metab Syndr Relat Disord
2009
7: 543-548
|
| 23762820 |
de Lorenzo C et al.:
Variants of insulin-signaling inhibitor genes in type 2 diabetes and related metabolic abnormalities
Int J Genomics
2013
2013
|
| 21492831 |
Garcia-Hernandez MH et al.:
Expression and function of P2X(7) receptor and CD39/Entpd1 in patients with type 2 diabetes and their association with biochemical parameters
Cell. Immunol.
2011
269: 135-143
|
| 18567823 |
Enjyoji K et al.:
Deletion of cd39/entpd1 results in hepatic insulin resistance
Diabetes
2008
57: 2311-2320
|
| 17473221 |
Friedman DJ et al.:
The vascular ectonucleotidase ENTPD1 is a novel renoprotective factor in diabetic nephropathy
Diabetes
2007
56: 2371-2379
|
| 25717362 |
McCoy E et al.:
Deletion of ENTPD3 does not impair nucleotide hydrolysis in primary somatosensory neurons or spinal cord
F
1000
3: 163
|
| 24085034 |
Syed SK et al.:
Ectonucleotidase NTPDase3 is abundant in pancreatic beta-cells and regulates glucose-induced insulin secretion
Am. J. Physiol. Endocrinol. Metab.
2013
305
|
| 24359819 |
Seo J et al.:
Hepatic purinergic signaling gene network expression and its relationship with inflammation and oxidative stress biomarkers in blood from peripartal dairy cattle
J. Dairy Sci.
2014
97: 861-873
|
| 18801407 |
Nagy G et al.:
P2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients
Prog. Neuropsychopharmacol. Biol. Psychiatry
2008
32: 1884-1888
|
| 21333941 |
Fausther M et al.:
Extracellular nucleosides and nucleotides regulate liver functions via a complex system of membrane proteins
C. R. Biol.
2011
334: 100-117
|
| 22555564 |
Zimmermann H et al.:
Cellular function and molecular structure of ecto-nucleotidases
Purinergic Signal.
2012
8: 437-502
|
| 23390342 |
Singh H et al.:
Novel genes underlying beta cell survival in metabolic stress
Bioinformation
2013
9: 37-41
|
| 25374514 |
Buckman LB et al.:
The contribution of hypothalamic macroglia to the regulation of energy homeostasis
Front Syst Neurosci
2014
8: 212
|
| 27422516 |
Arrieta-Cruz I et al.:
The Role of Circulating Amino Acids in the Hypothalamic Regulation of Liver Glucose Metabolism
Adv Nutr
2016
7: 790S-797S
|
| 22662313 |
Fausther M et al.:
Role of purinergic P2X receptors in the control of liver homeostasis
Wiley Interdiscip Rev Membr Transp Signal
2012
1: 341-348
|
| 29526844 |
Taghizadeh M et al.:
Effects of endurance training on hsa-miR-223, P2RY12 receptor expression and platelet function in type 2 diabetic patients
Clin. Hemorheol. Microcirc.
2018
68: 391-399
|
| 27975100 |
Fejes Z et al.:
Hyperglycaemia suppresses microRNA expression in platelets to increase P2RY12 and SELP levels in type 2 diabetes mellitus
Thromb. Haemost.
2017
117: 529-542
|
| 26175178 |
Yang S et al.:
Biomarkers Associated with Ischemic Stroke in Diabetes Mellitus Patients
Cardiovasc. Toxicol.
2016
16: 213-222
|
| 26844282 |
Malo MS et al.:
A High Level of Intestinal Alkaline Phosphatase Is Protective Against Type 2 Diabetes Mellitus Irrespective of Obesity
EBioMedicine
2015
2: 2016-2023
|
| 25469308 |
Johnson ME et al.:
Two novel type 2 diabetes loci revealed through integration of TCF7L2 DNA occupancy and SNP association data
BMJ Open Diabetes Res Care
2014
2
|
| 30458128 |
Li X et al.:
SIRT1 activation promotes angiogenesis in diabetic wounds by protecting endothelial cells against oxidative stress
Arch. Biochem. Biophys.
2019
661: 117-124
|
| 24151200 |
Huang K et al.:
Whole exome sequencing identifies variation in CYB5A and RNF10 associated with adiposity and type 2 diabetes
Obesity (Silver Spring)
2014
22: 984-988
|
| 28521864 |
Honma K et al.:
Insulin-induced inhibition of gluconeogenesis genes, including glutamic pyruvic transaminase 2, is associated with reduced histone acetylation in a human liver cell line
Metab. Clin. Exp.
2017
71: 118-124
|
| 22007191 |
Nakatani S et al.:
Targeted proteomics of isolated glomeruli from the kidneys of diabetic rats: sorbin and SH3 domain containing 2 is a novel protein associated with diabetic nephropathy
Exp Diabetes Res
2011
2011
|
| 26447765 |
Uchiyama T et al.:
Angiotensin II Reduces Lipoprotein Lipase Expression in Visceral Adipose Tissue via Phospholipase C beta4 Depending on Feeding but Increases Lipoprotein Lipase Expression in Subcutaneous Adipose Tissue via c-Src
PLoS ONE
2015
10
|
| 15328404 |
Wiedmer T et al.:
Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3)
Proc. Natl. Acad. Sci. U.S.A.
2004
101
|
| 16738321 |
Yeom SY et al. et al.:
Regulation of insulin secretion and beta-cell mass by activating signal cointegrator 2
Mol. Cell. Biol.
2006
26: 4553-4563
|
| 29175050 |
Ramseyer VD et al.:
Vacuolar protein sorting 13C is a novel lipid droplet protein that inhibits lipolysis in brown adipocytes
Mol Metab
2018
7: 57-70
|
| 16306379 |
Karlberg N et al.:
Insulin resistance syndrome in subjects with mutated RING finger protein TRIM37
Diabetes
2005
54: 3577-3581
|
| 22939844 |
Andersson SA et al.:
Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes
Mol. Cell. Endocrinol.
2012
364: 36-45
|
| 30814610 |
Davey JS et al.:
Protein SUMOylation regulates insulin secretion at multiple stages
Sci Rep
2019
9: 2895
|
| 26635000 |
Craig TJ et al.:
SUMOylation of Syntaxin1A regulates presynaptic endocytosis
Sci Rep
2015
5: 17669
|
| 21173146 |
Kang Y et al.:
ATP modulates interaction of syntaxin-1A with sulfonylurea receptor 1 to regulate pancreatic beta-cell KATP channels
J. Biol. Chem.
2011
286: 5876-5883
|
| 18629868 |
Nielsen SK et al.:
Characterization of primary cilia and Hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines
Dev. Dyn.
2008
237: 2039-2052
|
| 30250206 |
Lagali NS et al.:
Dendritic cell maturation in the corneal epithelium with onset of type 2 diabetes is associated with tumor necrosis factor receptor superfamily member 9
Sci Rep
2018
8: 14248
|
| 24268657 |
Shalata A et al. et al.:
Morbid obesity resulting from inactivation of the ciliary protein CEP19 in humans and mice
Am. J. Hum. Genet.
2013
93: 1061-1071
|
| 28580277 |
Ndiaye FK et al. et al.:
Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion
Mol Metab
2017
6: 459-470
|
| 29042441 |
Sen S et al.:
Transcription factor 19 interacts with histone 3 lysine 4 trimethylation and controls gluconeogenesis via the nucleosome-remodeling-deacetylase complex
J. Biol. Chem.
2017
292
|
| 23860123 |
Krautkramer KA et al.:
Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 beta-cell line
Am. J. Physiol. Endocrinol. Metab.
2013
305: E600-E610
|
| 21820437 |
Kokkola T et al.:
Somatostatin receptor 5 is palmitoylated by the interacting ZDHHC5 palmitoyltransferase
FEBS Lett.
2011
585: 2665-2670
|
| 30619890 |
Bartoli-Leonard F et al.:
The Interplay of SIRT1 and Wnt Signaling in Vascular Calcification
Front Cardiovasc Med
2018
5: 183
|
| 31343992 |
author information missing
Gene loci associated with insulin secretion in islets from non-diabetic mice
|
| 29511320 |
Andersen E et al.:
Preadipocytes from obese humans with type 2 diabetes are epigenetically reprogrammed at genes controlling adipose tissue function
Int J Obes (Lond)
2019
43: 306-318
|
| 12118251 |
Savage DB et al. et al.:
Digenic inheritance of severe insulin resistance in a human pedigree
Nat. Genet.
2002
31: 379-384
|
| 24743941 |
Holt RI et al.:
Diabetes and depression
Curr. Diab. Rep.
2014
14: 491
|
| 20711716 |
Nouwen A et al.:
Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis
Diabetologia
2010
53: 2480-2486
|
| 31641639 |
Kumar PR et al.:
Effect of Sertraline as an Add-on Therapy in T2DM Patients with Comorbid Depression: An Open Label Randomized Controlled Trial
Indian J Endocrinol Metab
2019
23: 357-362
|
| 17327305 |
Lustman PJ et al.:
Factors influencing glycemic control in type 2 diabetes during acute- and maintenance-phase treatment of major depressive disorder with bupropion
Diabetes Care
2007
30: 459-466
|
| 23616185 |
Corral-Fernandez NE et al.:
Dysregulated miR-155 expression in peripheral blood mononuclear cells from patients with type 2 diabetes
Exp. Clin. Endocrinol. Diabetes
2013
121: 347-353
|
| 30469501 |
Nigi L et al.:
MicroRNAs as Regulators of Insulin Signaling: Research Updates and Potential Therapeutic Perspectives in Type 2 Diabetes
|
| 24455749 |
Chen J et al.:
Identifying candidate genes for Type 2 Diabetes Mellitus and obesity through gene expression profiling in multiple tissues or cells
J Diabetes Res
2013
2013
|
| 29387206 |
Cao MM et al.:
Resveratrol attenuates type 2 diabetes mellitus by mediating mitochondrial biogenesis and lipid metabolism via Sirtuin type 1
Exp Ther Med
2018
15: 576-584
|
| 27711113 |
Lin X et al. et al.:
MiR-155 Enhances Insulin Sensitivity by Coordinated Regulation of Multiple Genes in Mice
PLoS Genet.
2016
12
|
| 25760736 |
Liu F et al.:
Bioinformatics analysis of abnormal DNA methylation in muscle samples from monozygotic twins discordant for type 2 diabetes
Mol Med Rep
2015
12: 351-356
|
| 24921187 |
Daniel J et al.:
The ufm1 cascade
Cells
2014
3: 627-638
|
| 21216854 |
Schmid AI et al.:
Liver ATP synthesis is lower and relates to insulin sensitivity in patients with type 2 diabetes
Diabetes Care
2011
34: 448-453
|
| 31831727 |
Volta F et al.:
Glucose homeostasis is regulated by pancreatic beta-cell cilia via endosomal EphA-processing
Nat Commun
2019
10: 5686
|
| 16518343 |
Sweet DH et al.:
Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models
Kidney Int.
2006
69: 837-845
|
| 23949796 |
Sharma K et al. et al.:
Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease
J. Am. Soc. Nephrol.
2013
24: 1901-1912
|
| 28775995 |
Mousavi S et al.:
Pharmacogenetic variation of SLC47A1 gene and metformin response in type2 diabetes patients
Mol Biol Res Commun
2017
6: 91-94
|
| 30433870 |
Raj GM et al.:
Lack of effect of the SLC47A1 and SLC47A2 gene polymorphisms on the glycemic response to metformin in type 2 diabetes mellitus patients
Drug Metab Pers Ther
2018
33: 175-185
|
| 30286449 |
author information missing
Pancreatic Thyrotropin Releasing Hormone and Mechanism of Insulin Secretion
Cell. Physiol. Biochem.
2018
50: 378-384
|
| 23701881 |
Zhao K et al.:
Food-intake dysregulation in type 2 diabetic Goto-Kakizaki rats: hypothesized role of dysfunctional brainstem thyrotropin-releasing hormone and impaired vagal output
Neuroscience
2013
247: 43-54
|
| 31965758 |
Hoshino S et al. et al.:
WWP1 knockout in mice exacerbates obesity-related phenotypes in white adipose tissue but improves whole-body glucose metabolism
|
| 30830866 |
Hirata Y et al.:
Hyperglycemia induces skeletal muscle atrophy via a WWP1/KLF15 axis
|
| 23891624 |
Terra LF et al.:
Proteins differentially expressed in human beta-cells-enriched pancreatic islet cultures and human insulinomas
Mol. Cell. Endocrinol.
2013
381: 16-25
|
| 18508967 |
Murphy M et al. et al.:
IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis
J. Am. Soc. Nephrol.
2008
19: 1672-1680
|
| 28115289 |
Bhreathnach U et al.:
Profibrotic IHG-1 complexes with renal disease associated HSPA5 and TRAP1 in mitochondria
Biochim Biophys Acta Mol Basis Dis
2017
1863: 896-906
|
| 21360476 |
Lokman FE et al.:
Gene expression profiling in ethnic Malays with type 2 diabetes mellitus, with and without diabetic nephropathy
J. Nephrol.
2011
24: 778-789
|
| 15064952 |
Gonzalez M et al.:
Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells
Pflugers Arch.
2004
448: 383-394
|
| 12522122 |
Flores C et al.:
Rapid stimulation of L-arginine transport by D-glucose involves p42/44(mapk) and nitric oxide in human umbilical vein endothelium
Circ. Res.
2003
92: 64-72
|
| 29654945 |
Shi Y et al. et al.:
FOXO1 inhibition potentiates endothelial angiogenic functions in diabetes via suppression of ROCK1/Drp1-mediated mitochondrial fission
Biochim Biophys Acta Mol Basis Dis
2018
1864: 2481-2494
|
| 29768267 |
Wang P et al.:
Type 2 Diabetes Promotes Cell Centrosome Amplification via AKT-ROS-Dependent Signalling of ROCK1 and 14-3-3sigma
Cell. Physiol. Biochem.
2018
47: 356-367
|
| 28131915 |
Su D et al.:
ROCK1/p53/NOXA signaling mediates cardiomyocyte apoptosis in response to high glucose in vitro and vivo
Biochim Biophys Acta Mol Basis Dis
2017
1863: 936-946
|
| 24326423 |
Lee SH et al.:
ROCK1 isoform-specific deletion reveals a role for diet-induced insulin resistance
Am. J. Physiol. Endocrinol. Metab.
2014
306: E332-E343
|
| 19545435 |
Failli P et al.:
Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats
Cardiovasc Diabetol
2009
8: 32
|
| 19276091 |
Lee DH et al.:
Targeted disruption of ROCK1 causes insulin resistance in vivo
J. Biol. Chem.
2009
284
|
| 31173254 |
Li S et al.:
RING finger protein 10 is a potential drug target for diabetic vascular complications
Mol Med Rep
2019
20: 931-938
|
| 31932636 |
Hebbar P et al. et al.:
Genome-wide association study identifies novel risk variants from RPS6KA1, CADPS, VARS, and DHX58 for fasting plasma glucose in Arab population
Sci Rep
2020
10: 152
|
| 28598424 |
Ni Q et al.:
Raptor regulates functional maturation of murine beta cells
Nat Commun
2017
8: 15755
|
| 22926010 |
Freude T et al.:
Hyperinsulinemia reduces osteoblast activity in vitro via upregulation of TGF-beta
J. Mol. Med.
2012
90: 1257-1266
|
| 25359286 |
Meng N et al.:
Association of polymorphisms of angiotensin I converting enzyme 2 with retinopathy in type 2 diabetes mellitus among Chinese individuals
Eye (Lond)
2015
29: 266-271
|
| 30404071 |
Graus-Nunes F et al.:
The renin-angiotensin system as a target to solve the riddle of endocrine pancreas homeostasis
Biomed. Pharmacother.
2019
109: 639-645
|
| 22665935 |
Randriamboavonjy V et al.:
Calpain inhibition stabilizes the platelet proteome and reactivity in diabetes
Blood
2012
120: 415-423
|
| 26029927 |
Wang L et al.:
The ACE2/Ang-(1-7)/Mas Axis Regulates the Development of Pancreatic Endocrine Cells in Mouse Embryos
PLoS ONE
2015
10
|
| 32278764 |
Hussain A et al.:
COVID-19 and diabetes: Knowledge in progress
Diabetes Res. Clin. Pract.
2020
162
|
| 24962668 |
Fadini GP et al. et al.:
The molecular signature of impaired diabetic wound healing identifies serpinB3 as a healing biomarker
Diabetologia
2014
57: 1947-1956
|
| 28783104 |
Guenat D et al.:
Exosomes and Other Extracellular Vesicles in HPV Transmission and Carcinogenesis
|
| 19065996 |
Ribeiro-Oliveira A Jr et al.:
The renin-angiotensin system and diabetes: an update
Vasc Health Risk Manag
2008
4: 787-803
|
| 18064606 |
Puebla C et al.:
High D-glucose reduces SLC29A1 promoter activity and adenosine transport involving specific protein 1 in human umbilical vein endothelium
J. Cell. Physiol.
2008
215: 645-656
|
| 31145772 |
Zhang S et al.:
East Asian Genome-wide association study derived loci in relation to type 2 diabetes in the Han Chinese population
Acta Biochim. Pol.
2019
66: 159-165
|
| 23056385 |
Nita II et al.:
The mitochondrial Na+/Ca2+ exchanger upregulates glucose dependent Ca2+ signalling linked to insulin secretion
PLoS ONE
2012
7
|
| 29932866 |
Keller M et al. et al.:
DNA methylation of SSPN is linked to adipose tissue distribution and glucose metabolism
|
| 32294179 |
Drucker DJ et al.:
Coronavirus Infections and Type 2 Diabetes-Shared Pathways with Therapeutic Implications
|
| 25915126 |
Cebola I et al. et al.:
TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors
Nat. Cell Biol.
2015
17: 615-626
|
| 19325541 |
Nordquist N et al.:
The transcription factor TFAP2B is associated with insulin resistance and adiposity in healthy adolescents
Obesity (Silver Spring)
2009
17: 1762-1767
|
| 16954217 |
Ikeda K et al.:
Transcription factor activating enhancer-binding protein-2beta. A negative regulator of adiponectin gene expression
J. Biol. Chem.
2006
281
|
| 16373417 |
Tao Y et al.:
The transcription factor AP-2beta causes cell enlargement and insulin resistance in 3T3-L1 adipocytes
Endocrinology
2006
147: 1685-1696
|
| 15940393 |
Maeda S et al. et al.:
Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus
J. Hum. Genet.
2005
50: 283-292
|
| 16373396 |
Tsukada S et al.:
Intronic polymorphisms within TFAP2B regulate transcriptional activity and affect adipocytokine gene expression in differentiated adipocytes
Mol. Endocrinol.
2006
20: 1104-1111
|
| 30816805 |
Song W et al. et al.:
Endothelial TFEB (Transcription Factor EB) Restrains IKK (IkappaB Kinase)-p65 Pathway to Attenuate Vascular Inflammation in Diabetic db/db Mice
Arterioscler. Thromb. Vasc. Biol.
2019
39: 719-730
|
| 32334082 |
Liu F et al.:
ACE2 Expression in Pancreas May Cause Pancreatic Damage After SARS-CoV-2 Infection
|
| 32339533 |
Chee YJ et al.:
Diabetic ketoacidosis precipitated by Covid-19 in a patient with newly diagnosed diabetes mellitus
Diabetes Res. Clin. Pract.
2020
164
|
| 32314455 |
Li J et al.:
COVID-19 infection may cause ketosis and ketoacidosis
|
| 31707286 |
McClorry S et al.:
Effectiveness of vitamin D supplementation in Swedish children may be negatively impacted by BMI and serum fructose
J. Nutr. Biochem.
2020
75
|
| 30710421 |
Ji J et al.:
Type 2 diabetes is associated with suppression of autophagy and lipid accumulation in beta-cells
J. Cell. Mol. Med.
2019
23: 2890-2900
|
| 19034303 |
Reich HN et al.:
Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease
Kidney Int.
2008
74: 1610-1616
|
| 23893738 |
Chhabra KH et al.:
Angiotensin converting enzyme 2: a new important player in the regulation of glycemia
IUBMB Life
2013
65: 731-738
|
| 26968558 |
Lin M et al.:
Calcitriol regulates angiotensin-converting enzyme and angiotensin converting-enzyme 2 in diabetic kidney disease
Mol. Biol. Rep.
2016
43: 397-406
|
| 18371537 |
Mizuiri S et al.:
Expression of ACE and ACE2 in individuals with diabetic kidney disease and healthy controls
Am. J. Kidney Dis.
2008
51: 613-623
|
| 19375596 |
Saiki A et al.:
Circulating angiotensin II is associated with body fat accumulation and insulin resistance in obese subjects with type 2 diabetes mellitus
Metab. Clin. Exp.
2009
58: 708-713
|
| 24450744 |
Dominici FP et al.:
Modulation of the action of insulin by angiotensin-(1-7)
Clin. Sci.
2014
126: 613-630
|
| 16699725 |
Gu Y et al. et al.:
The -822G/A polymorphism in the promoter region of the MAP4K5 gene is associated with reduced risk of type 2 diabetes in Chinese Hans from Shanghai
J. Hum. Genet.
2006
51: 605-610
|
| 26238946 |
Abe S et al.:
Association of genetic variants with dyslipidemia
Mol Med Rep
2015
12: 5429-5436
|
| 32005965 |
Cilenti L et al.:
Mitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1alpha) and metabolic reprogramming by modulating the UBXN7 cofactor protein
Sci Rep
2020
10: 1609
|
| 18775313 |
Alexandru G et al.:
UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover
Cell
2008
134: 804-816
|
| 26076035 |
van der Meulen T et al.:
Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion
Nat. Med.
2015
21: 769-776
|
| 31781037 |
Kavalakatt S et al.:
Urocortin 3 Levels Are Impaired in Overweight Humans With and Without Type 2 Diabetes and Modulated by Exercise
Front Endocrinol (Lausanne)
2019
10: 762
|
| 31893569 |
Alarslan P et al.:
Increased urocortin 3 levels are associated with the risk of having type 2 diabetes mellitus
J Diabetes
2020
12: 474-482
|
| 22000474 |
Novembri R et al.:
Effects of urocortin 2 and urocortin 3 on IL-10 and TNF-alpha expression and secretion from human trophoblast explants
Placenta
2011
32: 969-974
|
| 17360501 |
Li C et al.:
Urocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasis
Proc. Natl. Acad. Sci. U.S.A.
2007
104: 4206-4211
|
| 18463714 |
Jiang Z et al.:
Comparative understanding of UTS2 and UTS2R genes for their involvement in type 2 diabetes mellitus
Int. J. Biol. Sci.
2008
4: 96-102
|
| 22587369 |
Okumus S et al.:
Association between Thr21Met and Ser89Asn polymorphisms of the urotensin-II (UTS2) gene, diabetes mellitus, and diabetic retinopathy
Curr. Eye Res.
2012
37: 921-929
|
| 15476949 |
Suzuki S et al.:
Genetic variations at urotensin II and urotensin II receptor genes and risk of type 2 diabetes mellitus in Japanese
Peptides
2004
25: 1803-1808
|
| 18338983 |
Suguro T et al.:
Increased plasma urotensin-II levels are associated with diabetic retinopathy and carotid atherosclerosis in Type 2 diabetes
Clin. Sci.
2008
115: 327-334
|
| 28202288 |
Kowluru A et al.:
Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction
Biochem. Pharmacol.
2017
132: 9-17
|
| 26224100 |
Veluthakal R et al.:
VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells
Diabetologia
2015
58: 2573-2581
|
| 26440364 |
Cheng YS et al.:
PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis
PLoS Genet
2015
11
|
| 22768837 |
Stephens SB et al.:
A VGF-derived peptide attenuates development of type 2 diabetes via enhancement of islet beta-cell survival and function
Cell Metab.
2012
16: 33-43
|
| 31815140 |
Zhang M et al.:
Serum Human Epididymis Protein 4 is Associated with Renal Function and Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus
Biomed Res Int
2019
2019
|
| 32150756 |
Zhou B et al. et al.:
N(6) -methyladenosine Reader Protein Ythdc2 Suppresses Liver Steatosis via Regulation of mRNA Stability of Lipogenic Genes
|
| 26075596 |
Han J et al.:
The Identification of Novel Protein-Protein Interactions in Liver that Affect Glucagon Receptor Activity
PLoS ONE
2015
10
|
| 28399188 |
Kazakova EV et al.:
The Gas6 gene rs8191974 and Ap3s2 gene rs2028299 are associated with type 2 diabetes in the northern Chinese Han population
Acta Biochim. Pol.
2017
64: 227-231
|
| 24979111 |
Gong JY et al.:
Association of platelet glycoprotein receptor alpha2beta1 integrin and glycoprotein IIIa gene polymorphisms with diabetic retinopathy: evidence from 3007 subjects
Curr. Eye Res.
2015
40: 476-483
|
| 30245959 |
Wang D et al.:
Human carboxylesterases: a comprehensive review
Acta Pharm Sin B
2018
8: 699-712
|
| 25233471 |
de Boer JF et al.:
Mitogen-activated protein kinase-activated protein kinase 2 deficiency reduces insulin sensitivity in high-fat diet-fed mice
PLoS ONE
2014
9
|
| 28318015 |
Krogh SS et al.:
Plasma levels of MASP-1, MASP-3 and MAp44 in patients with type 2 diabetes: influence of glycaemic control, body composition and polymorphisms in the MASP1 gene
Clin Exp Immunol
2017
189: 103-112
|
| 32277104 |
Qaddoumi MG et al.:
Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes
Sci Rep
2020
10: 6170
|
| 31593502 |
Chai W et al.:
Inhibiting myeloperoxidase prevents onset and reverses established high-fat diet-induced microvascular insulin resistance
Am. J. Physiol. Endocrinol. Metab.
2019
317
|
| 21112318 |
Karthik D et al.:
Characterization of the brain proteome of rats with diabetes mellitus through two-dimensional electrophoresis and mass spectrometry
Brain Res.
2011
1371: 171-179
|
| 12185156 |
Liolitsa D et al.:
Genetic variability in the insulin signalling pathway may contribute to the risk of late onset Alzheimers disease
J. Neurol. Neurosurg. Psychiatry
2002
73: 261-266
|
| 31604927 |
Yung T et al.:
Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals
Nat Commun
2019
10: 4647
|
| 26848587 |
Xie L et al.:
Syntaxin-3 Binds and Regulates Both R- and L-Type Calcium Channels in Insulin-Secreting INS-1 832/13 Cells
PLoS ONE
2016
11
|
| 28402446 |
Zha D et al.:
Adiponectin and Its Receptors in Diabetic Kidney Disease: Molecular Mechanisms and Clinical Potential
Endocrinology
2017
158: 2022-2034
|
| 30769897 |
Abbiss H et al.:
Metabolomics Approaches for the Diagnosis and Understanding of Kidney Diseases
|
| 31818149 |
Palizban AA et al.:
Role of rs7903146 polymorphism and adropin serum level in patients with diabetes mellitus; a case-control study from Isfahan, Iran
|
| 29669965 |
Zang H et al.:
Serum adropin levels are decreased in Chinese type 2 diabetic patients and negatively correlated with body mass index
Endocr J
2018
65: 685-691
|
| 30718926 |
Suzuki K et al. et al.:
Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population
Nat Genet
2019
51: 379-386
|
| 32173772 |
Hayder ZS et al.:
Resistin hormone in diabetic kidney disease and its relation to iron status and hepcidin
Int Urol Nephrol
2020
52: 749-756
|
| 29449563 |
Lim JH et al. et al.:
Cinacalcet-mediated activation of the CaMKKbeta-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy
Cell Death Dis
2018
9: 270
|
| 31861217 |
Gill V et al.:
Advanced Glycation End Products (AGEs) May Be a Striking Link Between Modern Diet and Health
|
| 16046297 |
Janssen B et al. et al.:
Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1
Diabetes
2005
54: 2320-2327
|
| 9928418 |
Hipkiss AR et al.:
Pluripotent protective effects of carnosine, a naturally occurring dipeptide
Ann N Y Acad Sci
1998
854: 37-53
|
| 12473676 |
Teufel M et al. et al.:
Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase
J Biol Chem
2003
278: 6521-6531
|
| 12617609 |
Hou WC et al.:
Antioxidant peptides with Angiotensin converting enzyme inhibitory activities and applications for Angiotensin converting enzyme purification
J Agric Food Chem
2003
51: 1706-1709
|
| 31545409 |
Hu H et al.:
Phosphoregulation of Cdc14A by pololike kinase 1 is involved in betacell function and cell cycle regulation
Mol Med Rep
2019
20: 4277-4284
|
| 1756686 |
Aoki Y et al.:
Contribution of hyperglycemia and renal damage to urinary C-peptide clearance in non-insulin-dependent diabetic patients
Diabetes Res Clin Pract
1991
14: 85-89
|
| 25303803 |
Kim MK et al.:
Clinical utility of serum beta-2-microglobulin as a predictor of diabetic complications in patients with type 2 diabetes without renal impairment
Diabetes Metab
2014
40: 459-465
|
| 11792765 |
Lonnemann G et al.:
Beta(2)-microglobulin amyloidosis: effects of ultrapure dialysate and type of dialyzer membrane
J Am Soc Nephrol
2002
13: Suppl 1 S72-S77
|
| 17065335 |
Schmid H et al. et al.:
Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy
Diabetes
2006
55: 2993-3003
|
| 30288572 |
Colombo M et al. et al.:
Serum kidney injury molecule 1 and beta2-microglobulin perform as well as larger biomarker panels for prediction of rapid decline in renal function in type 2 diabetes
Diabetologia
2019
62: 156-168
|
| 20674073 |
Ilyas R et al.:
High glucose disrupts oligosaccharide recognition function via competitive inhibition: a potential mechanism for immune dysregulation in diabetes mellitus
Immunobiology
2011
216: 126-131
|
| 32098346 |
Matoba K et al.:
Targeting Redox Imbalance as an Approach for Diabetic Kidney Disease
|
| 20667975 |
Liu Q et al.:
Activation of AMP-activated protein kinase signaling pathway by adiponectin and insulin in mouse adipocytes: requirement of acyl-CoA synthetases FATP1 and Acsl1 and association with an elevation in AMP/ATP ratio
FASEB J
2010
24: 4229-4239
|
| 16137686 |
Palanivel R et al.:
Regulation of fatty acid uptake and metabolism in L6 skeletal muscle cells by resistin
FEBS Lett
2005
579: 5049-5054
|
| 26536590 |
Akhtar S et al.:
Transactivation of ErbB Family of Receptor Tyrosine Kinases Is Inhibited by Angiotensin-(1-7) via Its Mas Receptor
PLoS One
2015
10
|
| 22238402 |
Rogers C et al.:
EGF receptor (ERBB1) abundance in adipose tissue is reduced in insulin-resistant and type 2 diabetic women
J Clin Endocrinol Metab
2012
97: E329-E340
|
| 19406626 |
Sharifi AM et al.:
Effect of short term treatment of L-carnitine on tissue ACE activity in streptozotocin-induced diabetic rats
Pathophysiology
2009
16: 53-56
|
| 24409655 |
Jeon YL et al.:
Cystatin C as an early marker of diabetic nephropathy in patients with type 2 diabetes
Clin Lab
2013
59: 1221-1229
|
| 31573977 |
Afshinnia F et al. et al.:
Increased lipogenesis and impaired beta-oxidation predict type 2 diabetic kidney disease progression in American Indians
|
| 20620995 |
Ellis JM et al.:
Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis
Cell Metab
2010
12: 53-64
|
| 32585310 |
Noordam R et al.:
Proteome-wide assessment of diabetes mellitus in Qatari identifies IGFBP-2 as a risk factor already with early glycaemic disturbances
Arch Biochem Biophys
2020
689
|
| 21458526 |
Cui J et al.:
A novel interaction between insulin-like growth factor binding protein-6 and the vitamin D receptor inhibits the role of vitamin D3 in osteoblast differentiation
Mol Cell Endocrinol
2011
338: 84-92
|
| 33110845 |
Mehalingam V et al.:
Thyroid dysfunction in patients with type 2 diabetes mellitus and its association with diabetic complications
J Family Med Prim Care
2020
9: 4277-4281
|
| 32337292 |
Chen Y et al.:
Thyroid Parameters and Kidney Disorder in Type 2 Diabetes: Results from the METAL Study
J Diabetes Res
2020
2020
|
| 29807366 |
Bujak M et al.:
Trefoil Factor 3 Deficiency Affects Liver Lipid Metabolism
Cell Physiol Biochem
2018
47: 827-841
|
| 24086476 |
Xue Y et al.:
Tff3, as a novel peptide, regulates hepatic glucose metabolism
PLoS One
2013
8
|
| 22679101 |
author information missing
Low serum levels of the innate immune component ficolin-3 is associated with insulin resistance and predicts the development of type 2 diabetes
J Mol Cell Biol
2012
4: 256-257
|
| 31500117 |
Seselja K et al.:
Effect of Tff3 Deficiency and ER Stress in the Liver
|
| 28877911 |
Zhu Y et al. et al.:
Hepatic GALE Regulates Whole-Body Glucose Homeostasis by Modulating Tff3 Expression
Diabetes
2017
66: 2789-2799
|
| 18258687 |
Fueger PT et al.:
Trefoil factor 3 stimulates human and rodent pancreatic islet beta-cell replication with retention of function
Mol Endocrinol
2008
22: 1251-1259
|
| 32433667 |
Viviano J et al.:
ERp29 as a regulator of Insulin biosynthesis
PLoS One
2020
15
|
| 31156553 |
Xu C et al.:
Abnormal Glucose Metabolism and Insulin Resistance Are Induced via the IRE1alpha/XBP-1 Pathway in Subclinical Hypothyroidism
Front Endocrinol (Lausanne)
2019
10: 303
|
| 22247486 |
Kaplan N et al.:
EphA2/Ephrin-A1 signaling complexes restrict corneal epithelial cell migration
Invest Ophthalmol Vis Sci
2012
53: 936-945
|
| 16400034 |
Ojima T et al.:
EphrinA1 inhibits vascular endothelial growth factor-induced intracellular signaling and suppresses retinal neovascularization and blood-retinal barrier breakdown
Am J Pathol
2006
168: 331-339
|
| 29804241 |
Kacso T et al.:
Adiponectin is related to markers of endothelial dysfunction and neoangiogenesis in diabetic patients
Int Urol Nephrol
2018
50: 1661-1666
|
| 23292509 |
Kacso IM et al.:
Low serum endothelial cell-selective adhesion molecule predicts increase in albuminuria in type 2 diabetes patients
Int Urol Nephrol
2013
45: 1319-1326
|
| 32475064 |
Zhou Y et al.:
Elevated circulating luteinizing hormone levels are associated with diabetic macroalbuminuria in Chinese men and postmenopausal women: A cross-sectional study
J Diabetes
2020
12: 819-833
|
| 18006641 |
Lu M et al.:
Adiponectin activates adenosine monophosphate-activated protein kinase and decreases luteinizing hormone secretion in LbetaT2 gonadotropes
Mol Endocrinol
2008
22: 760-771
|
| 14592936 |
Ho RC et al.:
p38gamma MAPK regulation of glucose transporter expression and glucose uptake in L6 myotubes and mouse skeletal muscle
Am J Physiol Regul Integr Comp Physiol
2004
286: R342-R349
|
| 23463002 |
Wang L et al.:
alpha-SNAP inhibits AMPK signaling to reduce mitochondrial biogenesis and dephosphorylates Thr172 in AMPKalpha in vitro
Nat Commun
2013
4: 1559
|
| 32567559 |
Ferreira JP et al. et al.:
Circulating plasma proteins and new-onset diabetes in a population-based study: proteomic and genomic insights from the STANISLAS cohort
Eur J Endocrinol
2020
183: 285-295
|
| 21949678 |
Pan CJ et al.:
SLC37A1 and SLC37A2 are phosphate-linked, glucose-6-phosphate antiporters
PLoS One
2011
6
|
| 21035442 |
Bauer S et al.:
Elevated free fatty acids and impaired adiponectin bioactivity contribute to reduced SOD2 protein in monocytes of type 2 diabetes patients
Exp Mol Pathol
2011
90: 101-106
|
| 28483914 |
Salma N et al.:
Tfe3 and Tfeb Transcriptionally Regulate Peroxisome Proliferator-Activated Receptor gamma2 Expression in Adipocytes and Mediate Adiponectin and Glucose Levels in Mice
|
| 15711099 |
Yenicesu M et al.:
Blockade of the renin-angiotensin system increases plasma adiponectin levels in type-2 diabetic patients with proteinuria
Nephron Clin Pract
2005
99: c115-c121
|
| 9389501 |
Carver RS et al.:
Hepatic expression of ErbB3 is repressed by insulin in a pathway sensitive to PI-3 kinase inhibitors
Endocrinology
1997
138: 5195-5201
|
| 21546932 |
Brown ML et al.:
Follistatin and follistatin like-3 differentially regulate adiposity and glucose homeostasis
Obesity (Silver Spring)
2011
19: 1940-1949
|
| 9398741 |
Leung KC et al.:
Stimulation of mitochondrial fatty acid oxidation by growth hormone in human fibroblasts
J Clin Endocrinol Metab
1997
82: 4208-4213
|
| 32733634 |
Zhang T et al.:
SOCS2 Inhibits Mitochondrial Fatty Acid Oxidation via Suppressing LepR/JAK2/AMPK Signaling Pathway in Mouse Adipocytes
Oxid Med Cell Longev
2020
2020
|
| 24760988 |
Rutkowsky JM et al.:
Acylcarnitines activate proinflammatory signaling pathways
Am J Physiol Endocrinol Metab
2014
306
|
| 17848569 |
Saito T et al.:
The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocation
J Biol Chem
2007
282
|
| 24813896 |
Ryu J et al. et al.:
APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor
Cell Rep
2014
7: 1227-1238
|
| 19416712 |
Cheng KK et al.:
APPL1 potentiates insulin-mediated inhibition of hepatic glucose production and alleviates diabetes via Akt activation in mice
Cell Metab
2009
9: 417-427
|
| 23793716 |
Wang C et al. et al.:
Deficiency of APPL1 in mice impairs glucose-stimulated insulin secretion through inhibition of pancreatic beta cell mitochondrial function
Diabetologia
2013
56: 1999-2009
|
| 29406784 |
Kido K et al.:
Resistance training recovers attenuated APPL1 expression and improves insulin-induced Akt signal activation in skeletal muscle of type 2 diabetic rats
Am J Physiol Endocrinol Metab
2018
314: E564-E571
|
| 21562756 |
Holmes RM et al. et al.:
Increased abundance of the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1) in patients with obesity and type 2 diabetes: evidence for altered adiponectin signalling
Diabetologia
2011
54: 2122-2131
|
| 22340213 |
Ma XW et al.:
Genetic variability in adapter proteins with APPL1/2 is associated with the risk of coronary artery disease in type 2 diabetes mellitus in Chinese Han population
Chin Med J (Engl)
2011
124: 3618-3621
|
| 22566644 |
Cheng KK et al.:
APPL1 potentiates insulin secretion in pancreatic beta cells by enhancing protein kinase Akt-dependent expression of SNARE proteins in mice
Proc Natl Acad Sci U S A
2012
109: 8919-8924
|
| 23909487 |
Cheng KK et al.:
TRAF6-mediated ubiquitination of APPL1 enhances hepatic actions of insulin by promoting the membrane translocation of Akt
Biochem J
2013
455: 207-216
|
| 20978232 |
Xin X et al.:
APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway
Am J Physiol Endocrinol Metab
2011
300: E103-E110
|
| 27246173 |
Ding Y et al.:
APPL1-mediated activation of STAT3 contributes to inhibitory effect of adiponectin on hepatic gluconeogenesis
Mol Cell Endocrinol
2016
433: 12-19
|
| 16249427 |
Koster JC et al.:
Diabetes and insulin secretion: the ATP-sensitive K+ channel (K ATP) connection
Diabetes
2005
54: 3065-3072
|
| 31151172 |
Cochrane V et al.:
Leptin-induced Trafficking of KATP Channels: A Mechanism to Regulate Pancreatic beta-cell Excitability and Insulin Secretion
|
| 24752311 |
Chen M et al.:
Association of PAX4 genetic variants with oral antidiabetic drugs efficacy in Chinese type 2 diabetes patients
Pharmacogenomics J
2014
14: 488-492
|
| 28282933 |
Lorenzo PI et al.:
The Diabetes-Linked Transcription Factor PAX4: From Gene to Functional Consequences
|
| 32329795 |
Huang T et al.:
Influence of IGF2BP2, HMG20A, and HNF1B genetic polymorphisms on the susceptibility to Type 2 diabetes mellitus in Chinese Han population
|
| 12475782 |
Matschinsky FM et al.:
Regulation of pancreatic beta-cell glucokinase: from basics to therapeutics
Diabetes
2002
51: Suppl 3 S394-S404
|
| 15728204 |
Ek J et al.:
The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes
J Clin Endocrinol Metab
2005
90: 3054-3059
|
| 33188364 |
Lim S et al.:
COVID-19 and diabetes mellitus: from pathophysiology to clinical management
Nat Rev Endocrinol
2021
17: 11-30
|
| 32233013 |
Guo W et al. et al.:
Diabetes is a risk factor for the progression and prognosis of COVID-19
|
| 32369736 |
Zhu L et al. et al.:
Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes
Cell Metab
2020
31: 1068-1077.e3
|
| 32784802 |
Taneera J et al.:
Expression Profile of SARS-CoV-2 Host Receptors in Human Pancreatic Islets Revealed Upregulation of ACE2 in Diabetic Donors
|
| 23942780 |
Hardtner C et al.:
High glucose activates the alternative ACE2/Ang-(1-7)/Mas and APN/Ang IV/IRAP RAS axes in pancreatic beta-cells
Int J Mol Med
2013
32: 795-804
|
| 30222958 |
Abrahao MV et al.:
Identification of insulin-regulated aminopeptidase (IRAP) in the rat pineal gland and the modulation of melatonin synthesis by angiotensin IV
Brain Res
2019
1704: 40-46
|
| 21330419 |
Yokota H et al.:
Higher levels of prorenin predict development of diabetic retinopathy in patients with type 2 diabetes
J Renin Angiotensin Aldosterone Syst
2011
12: 290-294
|
| 32669391 |
Obukhov AG et al.:
SARS-CoV-2 Infections and ACE2: Clinical Outcomes Linked With Increased Morbidity and Mortality in Individuals With Diabetes
Diabetes
2020
69: 1875-1886
|
| 29888466 |
Fernandez C et al.:
Plasma levels of the proprotein convertase furin and incidence of diabetes and mortality
J Intern Med
2018
284: 377-387
|
| 23230080 |
Jarajapu YP et al.:
Activation of the ACE2/angiotensin-(1-7)/Mas receptor axis enhances the reparative function of dysfunctional diabetic endothelial progenitors
Diabetes
2013
62: 1258-1269
|
| 31610731 |
Duan Y et al. et al.:
Bone Marrow-Derived Cells Restore Functional Integrity of the Gut Epithelial and Vascular Barriers in a Model of Diabetes and ACE2 Deficiency
Circ Res
2019
125: 969-988
|
| 33297431 |
Liao YH et al.:
Novel Molecular Evidence Related to COVID-19 in Patients with Diabetes Mellitus
|
| 32636061 |
Zhang Q et al.:
Clinical analysis of risk factors for severe COVID-19 patients with type 2 diabetes
J Diabetes Complications
2020
34
|
| 29128354 |
Shi TT et al.:
Angiotensin-converting enzyme 2 regulates mitochondrial function in pancreatic beta-cells
Biochem Biophys Res Commun
2018
495: 860-866
|
| 27430410 |
Zhang F et al.:
Antioxidant effect of angiotensin (17) in the protection of pancreatic beta cell function
Mol Med Rep
2016
14: 1963-1969
|
| 33133024 |
Muniangi-Muhitu H et al.:
Covid-19 and Diabetes: A Complex Bidirectional Relationship
Front Endocrinol (Lausanne)
2020
11
|
| 17167413 |
Danilczyk U et al. et al.:
Essential role for collectrin in renal amino acid transport
Nature
2006
444: 1088-1091
|
| 24745989 |
Chou JY et al.:
The SLC37 family of sugar-phosphate/phosphate exchangers
Curr Top Membr
2014
73: 357-382
|
| 21987533 |
Pessoa BS et al.:
Spironolactone improves nephropathy by enhancing glucose-6-phosphate dehydrogenase activity and reducing oxidative stress in diabetic hypertensive rat
J Renin Angiotensin Aldosterone Syst
2012
13: 56-66
|
| 30233283 |
Fawad Ali Shah S et al.:
ARG1 single nucleotide polymorphisms rs2781666 and rs2781665 confer risk of Type 2 diabetes mellitus
EXCLI J
2018
17: 847-855
|
| 23823476 |
Jeon TI et al.:
An SREBP-responsive microRNA operon contributes to a regulatory loop for intracellular lipid homeostasis
Cell Metab
2013
18: 51-61
|
| 30274012 |
author information missing
Relationship Between SLC22A1 and SLC22A4 Gene Polymorphisms and Risk of Type 2 Diabetes in Chinese Han Population
Clin Lab
2018
64: 1357-1361
|
| 23223571 |
Wang H et al.:
The Rab27a effector exophilin7 promotes fusion of secretory granules that have not been docked to the plasma membrane
Mol Biol Cell
2013
24: 319-330
|
| 12176990 |
Fukuda M et al.:
Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells
J Biol Chem
2002
277
|
| 16216924 |
Gomi H et al.:
Granuphilin molecularly docks insulin granules to the fusion machinery
J Cell Biol
2005
171: 99-109
|
| 11865063 |
Yi Z et al.:
The Rab27a/granuphilin complex regulates the exocytosis of insulin-containing dense-core granules
Mol Cell Biol
2002
22: 1858-1867
|
| 12058058 |
Coppola T et al.:
Pancreatic beta-cell protein granuphilin binds Rab3 and Munc-18 and controls exocytosis
Mol Biol Cell
2002
13: 1906-1915
|
| 21768089 |
Wang H et al.:
Loss of granuphilin and loss of syntaxin-1A cause differential effects on insulin granule docking and fusion
J Biol Chem
2011
286
|
| 30926667 |
Morita M et al. et al.:
Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis
Proc Natl Acad Sci U S A
2019
116: 7973-7981
|
| 32859966 |
Mostafa D et al.:
Loss of beta-cell identity and diabetic phenotype in mice caused by disruption of CNOT3-dependent mRNA deadenylation
Commun Biol
2020
3: 476
|
| 25774817 |
Prasad RB et al.:
Genetics of type 2 diabetes-pitfalls and possibilities
Genes (Basel)
2015
6: 87-123
|
| 26087900 |
Zheng JS et al.:
Modulation of the Association between the PEPD Variant and the Risk of Type 2 Diabetes by n-3 Fatty Acids in Chinese Hans
J Nutrigenet Nutrigenomics
2015
8: 36-43
|
| 19570817 |
Wang X et al.:
Molecular cloning of a novel secreted peptide, INM02, and regulation of its expression by glucose
J Endocrinol
2009
202: 355-364
|
| 34487921 |
author information missing
article information missing
|
| 24358186 |
author information missing
article information missing
|
| 27388475 |
author information missing
article information missing
|
| 23666872 |
author information missing
article information missing
|
| 19509460 |
author information missing
article information missing
|
| 28536105 |
author information missing
article information missing
|
| 32095531 |
author information missing
article information missing
|
| 34907913 |
author information missing
article information missing
|
| 35385705 |
author information missing
article information missing
|
| 30402908 |
author information missing
article information missing
|
| 23296094 |
author information missing
article information missing
|
| 26846565 |
author information missing
article information missing
|
| 26892522 |
author information missing
article information missing
|
| 36002887 |
author information missing
article information missing
|
| 29549241 |
author information missing
article information missing
|
| 28941595 |
author information missing
article information missing
|
| 28324172 |
author information missing
article information missing
|
| 14618447 |
author information missing
article information missing
|
| 22560213 |
author information missing
article information missing
|
| 24682914 |
author information missing
article information missing
|
| 26156880 |
author information missing
article information missing
|
| 27457614 |
author information missing
article information missing
|
| 22961720 |
author information missing
article information missing
|
| 34684308 |
author information missing
article information missing
|
| 28783532 |
author information missing
article information missing
|
| 12951168 |
author information missing
article information missing
|
| 18485513 |
author information missing
article information missing
|
| 25857502 |
author information missing
article information missing
|
| 29225068 |
author information missing
article information missing
|
| 29735414 |
author information missing
article information missing
|
| 22332087 |
author information missing
article information missing
|
| 29241574 |
author information missing
article information missing
|
| 35931683 |
author information missing
article information missing
|
| 24296356 |
author information missing
article information missing
|
| 32433647 |
author information missing
article information missing
|
| 8526932 |
author information missing
article information missing
|
| 12676959 |
author information missing
article information missing
|
| 10900005 |
author information missing
article information missing
|
| 26284071 |
author information missing
article information missing
|
| 25216328 |
author information missing
article information missing
|
| 7927537 |
author information missing
article information missing
|
| 12690074 |
author information missing
article information missing
|
| 16752891 |
author information missing
article information missing
|
| 15448155 |
author information missing
article information missing
|
| 15353589 |
author information missing
article information missing
|
| 24130353 |
author information missing
article information missing
|
| 24257158 |
author information missing
article information missing
|
| 19011639 |
author information missing
article information missing
|
| 20178363 |
author information missing
article information missing
|
| 21299233 |
author information missing
article information missing
|
| 8596018 |
author information missing
article information missing
|
| 7539799 |
author information missing
article information missing
|
| 30674032 |
author information missing
article information missing
|
| 28122713 |
author information missing
article information missing
|
| 14691230 |
author information missing
article information missing
|
| 893413 |
author information missing
article information missing
|
| 17352516 |
author information missing
article information missing
|
| 16338283 |
author information missing
article information missing
|
| 16912128 |
author information missing
article information missing
|
| 26826382 |
author information missing
article information missing
|
| 33854350 |
author information missing
article information missing
|
| 33148870 |
author information missing
article information missing
|
| 21198750 |
author information missing
article information missing
|
| 10951221 |
author information missing
article information missing
|
| 15464987 |
author information missing
article information missing
|
| 15842525 |
author information missing
article information missing
|
| 16644672 |
author information missing
article information missing
|
| 24660890 |
author information missing
article information missing
|
| 19330494 |
author information missing
article information missing
|
| 23464664 |
author information missing
article information missing
|
| 27328054 |
author information missing
article information missing
|
| 25336915 |
author information missing
article information missing
|
| 18809631 |
author information missing
article information missing
|
| 28853228 |
author information missing
article information missing
|
| 33081425 |
author information missing
article information missing
|
| 20002082 |
author information missing
article information missing
|
| 25819061 |
author information missing
article information missing
|
| 31990936 |
author information missing
article information missing
|
| 32539832 |
author information missing
article information missing
|
| 28368447 |
author information missing
article information missing
|
| 26111634 |
author information missing
article information missing
|
| 36007775 |
author information missing
article information missing
|
| 16931572 |
author information missing
article information missing
|
| 23592482 |
author information missing
article information missing
|
| 34446852 |
author information missing
article information missing
|
| 35310970 |
author information missing
article information missing
|
| 36826505 |
author information missing
article information missing
|
| 19691494 |
author information missing
article information missing
|
| 26358774 |
author information missing
article information missing
|
| 36587752 |
author information missing
article information missing
|
| 18755801 |
author information missing
article information missing
|
| 38909044 |
author information missing
article information missing
|
| 32554797 |
author information missing
article information missing
|
| 37771334 |
author information missing
article information missing
|
| 30263000 |
author information missing
article information missing
|
| 19786696 |
Ogiwara I et al.:
De novo mutations of voltage-gated sodium channel alphaII gene SCN2A in intractable epilepsies
Neurology
2009
73: 1046-1053
|
| 11463517 |
Moore T et al.:
Polymorphism analysis of JRK/JH8, the human homologue of mouse jerky, and description of a rare mutation in a case of CAE evolving to JME.
Epilepsy Res.
2001
46: 157-167
|
| 19542233 |
Puri R et al.:
Hyperphosphorylation and aggregation of Tau in laforin-deficient mice, an animal model for Lafora disease.
J. Biol. Chem.
2009
284
|
| 20133599 |
Fukata Y et al.:
Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 3799-3804
|
| 20130004 |
Yu YE et al.:
Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability
Hum. Mol. Genet.
2010
19: 1702-1711
|
| 19796686 |
Owuor K et al.:
LGI1-associated epilepsy through altered ADAM23-dependent neuronal morphology
Mol. Cell. Neurosci.
2009
42: 448-457
|
| 12121305 |
Bertrand D et al.:
How mutations in the nAChRs can cause ADNFLE epilepsy.
Epilepsia
2002
43: 112-122
|
| 19063970 |
Zhao CJ et al.:
Neuronal Ca2+ sensor VILIP-1 leads to the upregulation of functional alpha4beta2 nicotinic acetylcholine receptors in hippocampal neurons
Mol. Cell. Neurosci.
2009
40: 280-292
|
| 18825662 |
Chiu C et al.:
Developmental impact of a familial GABAA receptor epilepsy mutation
Ann. Neurol.
2008
64: 284-293
|
| 19292758 |
Sijben AE et al.:
Does a SCN1A gene mutation confer earlier age of onset of febrile seizures in GEFS+?
Epilepsia
2009
50: 953-956
|
| 19803210 |
Savina TA et al.:
[Single audiogenic seizure promotes the increased levels of calcineurin and Ca(2+)-calmodulin-dependent protein kinase II in the rat brain]
Ross Fiziol Zh Im I M Sechenova
2009
95: 813-819
|
| 19605733 |
Vilas GL et al.:
Characterization of an epilepsy-associated variant of the human Cl-/HCO3(-) exchanger AE3.
Am. J. Physiol.
2009
297: C526-C536
|
| 17615250 |
Fedi M et al.:
Intracortical hyperexcitability in humans with a GABAA receptor mutation.
Cereb. Cortex
2008
18: 664-669
|
| 19605630 |
Cacheaux LP et al.:
Transcriptome profiling reveals TGF-beta signaling involvement in epileptogenesis
J. Neurosci.
2009
29: 8927-8935
|
| 11748509 |
Harkin LA et al.:
Truncation of the GABA(A)-receptor gamma2 subunit in a family with generalized epilepsy with febrile seizures plus.
Am. J. Hum. Genet.
2002
70: 530-536
|
| 9697698 |
Wallace RH et al.:
Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B.
Nat. Genet.
1998
19: 366-370
|
| 19710327 |
Patino GA et al.:
A functional null mutation of SCN1B in a patient with Dravet syndrome
J. Neurosci.
2009
29
|
| 22106086 |
Saitsu H et al. et al.:
Early infantile epileptic encephalopathy associated with the disrupted gene encoding Slit-Robo Rho GTPase activating protein 2 (SRGAP2)
Am J Med Genet A
2012
158A: 199-205
|
| 11326275 |
Wallace RH et al.:
Mutant GABA(A) receptor gamma2-subunit in childhood absence epilepsy and febrile seizures.
Nat. Genet.
2001
28: 49-52
|
| 12415111 |
Bowser DN et al.:
Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [gamma 2(R43Q)] found in human epilepsy
Proc. Natl. Acad. Sci. U.S.A.
2002
99
|
| 19723291 |
D'Alimonte I et al.:
Altered distribution and function of A2A adenosine receptors in the brain of WAG/Rij rats with genetic absence epilepsy, before and after appearance of the disease
Eur. J. Neurosci.
2009
30: 1023-1035
|
| 18922788 |
Lund IV et al.:
BDNF selectively regulates GABAA receptor transcription by activation of the JAK/STAT pathway
Sci Signal
2008
1: RA9
|
| 18809912 |
Roseti C et al.:
Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors.
Proc. Natl. Acad. Sci. U.S.A.
2008
105
|
| 18555494 |
Auta J et al.:
Imidazenil: a low efficacy agonist at alpha1- but high efficacy at alpha5-GABAA receptors fail to show anticonvulsant cross tolerance to diazepam or zolpidem
Neuropharmacology
2008
55: 148-153
|
| 18784617 |
Kwan P et al.:
Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression
Pharmacogenet. Genomics
2008
18: 989-998
|
| 18031550 |
Kile KB et al.:
Scn2a sodium channel mutation results in hyperexcitability in the hippocampus in vitro
Epilepsia
2008
49: 488-499
|
| 19853022 |
Guo F et al.:
Abnormal expressions of glutamate transporters and metabotropic glutamate receptor 1 in the spontaneously epileptic rat hippocampus
Brain Res. Bull.
2010
81: 510-516
|
| 19836362 |
NGouemo P et al.:
Seizure susceptibility is associated with altered protein expression of voltage-gated calcium channel subunits in inferior colliculus neurons of the genetically epilepsy-prone rat
Brain Res.
2010
1308: 153-157
|
| 19831124 |
Sarnat HB et al.:
Alpha-B-crystallin as a tissue marker of epileptic foci in paediatric resections.
Can J Neurol Sci
2009
36: 566-574
|
| 19726656 |
Huang Z et al.:
Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis.
J. Neurosci.
2009
29
|
| 19710312 |
David Y et al.:
Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis?
J. Neurosci.
2009
29
|
| 19666602 |
Clapcote SJ et al.:
Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS.
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 19288191 |
Li YQ et al.:
Up-regulation of epithelial membrane protein-1 in the temporal neocortex of patients with intractable epilepsy.
Neurochem. Res.
2009
34: 1594-1602
|
| 19064123 |
Hajsadeghi S et al.:
Serum levels of cardiac troponin I in patients with uncomplicated epileptic seizure.
Arch. Med. Res.
2009
40: 24-28
|
| 11587552 |
Pal S et al.:
Epileptogenesis induces long-term alterations in intracellular calcium release and sequestration mechanisms in the hippocampal neuronal culture model of epilepsy.
Cell Calcium
2001
30: 285-296
|
| 19660546 |
Galic MA et al.:
Viral-like brain inflammation during development causes increased seizure susceptibility in adult rats
Neurobiol. Dis.
2009
36: 343-351
|
| 8272259 |
Yoneda Y et al.:
Selectively high expression of the transcription factor AP1 in telencephalic structures of epileptic E1 mice
Neurosci. Lett.
1993
161: 161-164
|
| 1709015 |
Minami M et al.:
Effects of kainic acid on messenger RNA levels of IL-1 beta, IL-6, TNF alpha and LIF in the rat brain.
Biochem. Biophys. Res. Commun.
1991
176: 593-598
|
| 20214679 |
Aronica E et al.:
Expression pattern of miR-146a, an inflammation-associated microRNA, in experimental and human temporal lobe epilepsy.
Eur. J. Neurosci.
2010
31: 1100-1107
|
| 17613723 |
Namiki K et al.:
Involvement of p38alpha in kainate-induced seizure and neuronal cell damage.
J. Recept. Signal Transduct. Res.
2007
27: 99-111
|
| 19775068 |
Rao RS et al.:
Role of different cytokines and seizure susceptibility: a new dimension towards epilepsy research.
Indian J. Exp. Biol.
2009
47: 625-634
|
| 19285115 |
Balosso S et al.:
Molecular and functional interactions between tumor necrosis factor-alpha receptors and the glutamatergic system in the mouse hippocampus: implications for seizure susceptibility.
Neuroscience
2009
161: 293-300
|
| 19621265 |
Godukhin OV et al.:
The effects of interleukin-10 on the development of epileptiform activity in the hippocampus induced by transient hypoxia, bicuculline, and electrical kindling.
Neurosci. Behav. Physiol.
2009
39: 625-631
|
| 19366663 |
Paradiso B et al.:
Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model.
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 7191-7196
|
| 17387333 |
Kanter-Schlifke I et al.:
Seizure suppression by GDNF gene therapy in animal models of epilepsy
Mol. Ther.
2007
15: 1106-1113
|
| 17386052 |
Librizzi L et al.:
Expression of adhesion factors induced by epileptiform activity in the endothelium of the isolated guinea pig brain in vitro
Epilepsia
2007
48: 743-751
|
| 20446108 |
Lin Y et al.:
Mitochondrial DNA damage and the involvement of antioxidant defense and repair system in hippocampi of rats with chronic seizures.
Cell. Mol. Neurobiol.
2010
30: 947-954
|
| 18375135 |
Cosgrave AS et al.:
Regulation of activity-dependent neuroprotective protein (ADNP) by the NO-cGMP pathway in the hippocampus during kainic acid-induced seizure.
Neurobiol. Dis.
2008
30: 281-292
|
| 18457833 |
Akula KK et al.:
Nitric oxide signaling pathway in the anti-convulsant effect of adenosine against pentylenetetrazol-induced seizure threshold in mice.
Eur. J. Pharmacol.
2008
587: 129-134
|
| 21062633 |
dos Santos PS et al.:
Lipoic acid inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after pilocarpine-induced seizures
Pharmacol. Biochem. Behav.
2011
97: 531-536
|
| 20979657 |
Kim DW et al.:
Effects of creatine and beta-guanidinopropionic acid and alterations in creatine transporter and creatine kinases expression in acute seizure and chronic epilepsy models.
BMC Neurosci
2010
11: 141
|
| 11879979 |
Mohanan PV et al.:
Preventive effect of melatonin against brain mitochondria DNA damage, lipid peroxidation and seizures induced by kainic acid
Toxicol. Lett.
2002
129: 99-105
|
| 12573517 |
Yamamoto HA et al.:
Ganglioside GT1B and melatonin inhibit brain mitochondrial DNA damage and seizures induced by kainic acid in mice
Brain Res.
2003
964: 100-106
|
| 12573517 |
Yamamoto HA et al.:
Ganglioside GT1B and melatonin inhibit brain mitochondrial DNA damage and seizures induced by kainic acid in mice
Brain Res.
2003
964: 100-106
|
| 15370175 |
Yalcin A et al.:
Effect of melatonin cotreatment against kainic acid on coenzyme Q10, lipid peroxidation and Trx mRNA in rat hippocampus.
Int. J. Neurosci.
2004
114: 1085-1097
|
| 15050713 |
Yalcin A et al.:
Altered gene expressions in rat hippocampus after kainate injection with or without melatonin pre-treatment.
Neurosci. Lett.
2004
359: 65-68
|
| 16807920 |
Bough KJ et al.:
Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet
Ann. Neurol.
2006
60: 223-235
|
| 20211146 |
Malinska D et al.:
Complex III-dependent superoxide production of brain mitochondria contributes to seizure-related ROS formation.
Biochim. Biophys. Acta
2010
1797: 1163-1170
|
| 20077427 |
Zhao S et al.:
Nuclear translocation of mitochondrial cytochrome c, lysosomal cathepsins B and D, and three other death-promoting proteins within the first 60 minutes of generalized seizures.
J. Neurosci. Res.
2010
88: 1727-1737
|
| 18816793 |
Shin EJ et al.:
Protection against kainate neurotoxicity by ginsenosides: attenuation of convulsive behavior, mitochondrial dysfunction, and oxidative stress
J. Neurosci. Res.
2009
87: 710-722
|
| 20413803 |
Berger I et al.:
The effect of antiepileptic drugs on mitochondrial activity: a pilot study.
J. Child Neurol.
2010
25: 541-545
|
| 12890507 |
Yus-Najera E et al.:
Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation
Neuroscience
2003
120: 353-364
|
| 29670100 |
Yamagata A et al.:
Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22
Nat Commun
2018
9: 1546
|
| 25530618 |
Puchalowicz K et al.:
P2X and P2Y receptors-role in the pathophysiology of the nervous system
Int J Mol Sci
2014
15
|
| 21320622 |
Matute C et al.:
Neuroglial interactions mediated by purinergic signalling in the pathophysiology of CNS disorders
Semin. Cell Dev. Biol.
2011
22: 252-259
|
| 30733878 |
Rincon A et al.:
8q22.2q22.3 Microdeletion Syndrome Associated with Hearing Loss and Intractable Epilepsy
Case Rep Genet
2019
2019
|
| 21964664 |
Harrison V et al.:
Compound heterozygous deletion of NRXN1 causing severe developmental delay with early onset epilepsy in two sisters
Am. J. Med. Genet. A
2011
155
|
| 22211739 |
et al.:
Association of genomic deletions in the STXBP1 gene with Ohtahara syndrome
Clin Genet
2012
81: 399-402
|
| 29433947 |
Daif A et al.:
Antiglutamic acid decarboxylase 65 (GAD65) antibody-associated epilepsy
Epilepsy Behav
2018
80: 331-336
|
| 28584127 |
Bekenstein U et al.:
Dynamic changes in murine forebrain miR-211 expression associate with cholinergic imbalances and epileptiform activity
Proc. Natl. Acad. Sci. U.S.A.
2017
114
|
| 27677248 |
Chen LL et al.:
Neural Progenitor Cells Rptor Ablation Impairs Development but Benefits to Seizure-Induced Behavioral Abnormalities
CNS Neurosci Ther
2016
22: 1000-1008
|
| 15492041 |
Nakatsu F et al. et al.:
Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor
J. Cell Biol.
2004
167: 293-302
|
| 24337656 |
Baum L et al. et al.:
Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy
Hum. Genet.
2014
133: 651-659
|
| 16583313 |
Yang JW et al.:
Aberrant expression of cytoskeleton proteins in hippocampus from patients with mesial temporal lobe epilepsy
Amino Acids
2006
30: 477-493
|
| 16771832 |
Stragier B et al.:
Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats
J Neurochem
2006
98: 1100-1113
|
| 34837825 |
author information missing
article information missing
|
| 18550034 |
Li X et al.:
Long-term expressional changes of Na+ -K+ -Cl- co-transporter 1 (NKCC1) and K+ -Cl- co-transporter 2 (KCC2) in CA1 region of hippocampus following lithium-pilocarpine induced status epilepticus (PISE).
Brain Res.
2008
1221: 141-146
|
| 19845731 |
Wusthoff CJ et al.:
The ketogenic diet in treatment of two adults with prolonged nonconvulsive status epilepticus.
Epilepsia
2010
51: 1083-1085
|
| 19779207 |
Kumada T et al.:
Modified Atkins diet for the treatment of nonconvulsive status epilepticus in children
J. Child Neurol.
2010
25: 485-489
|
| 19686240 |
Unsain N et al.:
Brain-derived neurotrophic factor facilitates TrkB down-regulation and neuronal injury after status epilepticus in the rat hippocampus
J. Neurochem.
2009
111: 428-440
|
| 19501060 |
Bracey JM et al.:
Prolonged seizure activity leads to increased Protein Kinase A activation in the rat pilocarpine model of status epilepticus.
Brain Res.
2009
1283: 167-176
|
| 19357270 |
Graef JD et al.:
An acquired channelopathy involving thalamic T-type Ca2+ channels after status epilepticus
J. Neurosci.
2009
29: 4430-4441
|
| 19052226 |
Becker AJ et al.:
Transcriptional upregulation of Cav3.2 mediates epileptogenesis in the pilocarpine model of epilepsy.
J. Neurosci.
2008
28
|
| 19879360 |
Lopez-Meraz ML et al.:
Vulnerability of postnatal hippocampal neurons to seizures varies regionally with their maturational stage.
Neurobiol. Dis.
2010
37: 394-402
|
| 19875051 |
Yamada A et al.:
Glucose utilization in the brain during acute seizure is a useful biomarker for the evaluation of anticonvulsants: effect of methyl ethyl ketone in lithium-pilocarpine status epilepticus rats
Nucl. Med. Biol.
2009
36: 949-954
|
| 19800952 |
de Freitas RL et al.:
Oxidative stress in rat hippocampus caused by pilocarpine-induced seizures is reversed by buspirone
Brain Res. Bull.
2010
81: 505-509
|
| 12713643 |
Bymaster FP et al.:
Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine-induced seizure activity.
Eur. J. Neurosci.
2003
17: 1403-1410
|
| 18664591 |
Thomas RL et al.:
G protein coupling and signaling pathway activation by m1 muscarinic acetylcholine receptor orthosteric and allosteric agonists
J. Pharmacol. Exp. Ther.
2008
327: 365-374
|
| 8263518 |
Jope RS et al.:
Agonist-induced, GTP-dependent phosphoinositide hydrolysis in postmortem human brain membranes.
J. Neurochem.
1994
62: 180-186
|
| 1471196 |
Savolainen KM et al.:
Second messengers in cholinergic-induced convulsions and neuronal injury
Toxicol. Lett.
1992
64-65: Spec No 437-445
|
| 1648604 |
Nakanishi S et al.:
Immunohistochemical localization of an inositol 1,4,5-trisphosphate receptor, P400, in neural tissue: studies in developing and adult mouse brain
J. Neurosci.
1991
11: 2075-2086
|
| 18406528 |
Nagarkatti N et al.:
Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture.
Neurosci. Lett.
2008
436: 289-293
|
| 11283235 |
Sanabria ER et al.:
Initiation of network bursts by Ca2+-dependent intrinsic bursting in the rat pilocarpine model of temporal lobe epilepsy.
J. Physiol. (Lond.)
2001
532: 205-216
|
| 8792330 |
Fernandes MJ et al.:
Na+K+ ATPase activity in the rat hippocampus: a study in the pilocarpine model of epilepsy.
Neurochem. Int.
1996
28: 497-500
|
| 19371577 |
Zibell G et al.:
Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition.
Neuropharmacology
2009
56: 849-855
|
| 19222700 |
Irier HA et al.:
Translational regulation of GluR2 mRNAs in rat hippocampus by alternative 3 untranslated regions.
J. Neurochem.
2009
109: 584-594
|
| 19175401 |
Sandow N et al.:
Glutamine induces epileptiform discharges in superficial layers of the medial entorhinal cortex from pilocarpine-treated chronic epileptic rats in vitro.
Epilepsia
2009
50: 849-858
|
| 19126440 |
Lin TC et al.:
Neonatal status epilepticus alters prefrontal-striatal circuitry and enhances methamphetamine-induced behavioral sensitization in adolescence
Epilepsy Behav
2009
14: 316-323
|
| 18585369 |
Ermolinsky B et al.:
Differential changes in mGlu2 and mGlu3 gene expression following pilocarpine-induced status epilepticus: a comparative real-time PCR analysis.
Brain Res.
2008
1226: 173-180
|
| 18479396 |
Chu K et al.:
Erythropoietin reduces epileptogenic processes following status epilepticus
Epilepsia
2008
49: 1723-1732
|
| 18439803 |
Khongsombat O et al.:
Acute effects of N-(2-propylpentanoyl)urea on hippocampal amino acid neurotransmitters in pilocarpine-induced seizure in rats
Epilepsy Res.
2008
79: 151-157
|
| 14675153 |
Zhang G et al.:
Long-term alterations in glutamate receptor and transporter expression following early-life seizures are associated with increased seizure susceptibility
J. Neurochem.
2004
88: 91-101
|
| 20026167 |
Santos IM et al.:
Lipoic acid blocks seizures induced by pilocarpine via increases in delta-aminolevulinic dehydratase and Na+, K+-ATPase activity in rat brain
Pharmacol. Biochem. Behav.
2010
95: 88-91
|
| 19669875 |
de Freitas RM et al.:
Lipoic Acid increases hippocampal choline acetyltransferase and acetylcholinesterase activities and improvement memory in epileptic rats
Neurochem. Res.
2010
35: 162-170
|
| 19800361 |
de Freitas RM et al.:
Neurochemical changes on oxidative stress in rat hippocampus during acute phase of pilocarpine-induced seizures.
Pharmacol. Biochem. Behav.
2010
94: 341-345
|
| 18289526 |
Deshpande LS et al.:
Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: role of NMDA receptor activation and NMDA dependent calcium entry.
Eur. J. Pharmacol.
2008
583: 73-83
|
| 8112229 |
Cavalheiro EA et al.:
Spontaneous recurrent seizures in rats: amino acid and monoamine determination in the hippocampus.
Epilepsia
1994
35: 1-11
|
| 14746897 |
Costa MS et al.:
Pilocarpine-induced status epilepticus increases glutamate release in rat hippocampal synaptosomes.
Neurosci. Lett.
2004
356: 41-44
|
| 15288437 |
Costa MS et al.:
Status epilepticus induced by pilocarpine and Ca2+ transport by microsome in the hippocampus of rats.
Neurosci. Lett.
2004
366: 292-296
|
| 15104385 |
Funke MG et al.:
Calcium homeostasis and temporal lobe epilepsy
Arq Neuropsiquiatr
2003
61: 8-14
|
| 14706732 |
Scorza CA et al.:
Levels of the synaptic protein X11 alpha/mint1 are increased in hippocampus of rats with epilepsy.
Epilepsy Res.
2003
57: 49-57
|
| 18988310 |
Zhang HJ et al.:
Cyclooxygenase-2 inhibitor inhibits hippocampal synaptic reorganization in pilocarpine-induced status epilepticus rats.
J Zhejiang Univ Sci B
2008
9: 903-915
|
| 9766394 |
Funke MG et al.:
Tyrosine phosphorylation is increased in the rat hippocampus during the status epilepticus induced by pilocarpine.
Brain Res. Bull.
1998
47: 87-93
|
| 15748156 |
Niimura M et al.:
Changes in phosphorylation of the NMDA receptor in the rat hippocampus induced by status epilepticus.
J. Neurochem.
2005
92: 1377-1385
|
| 10582521 |
Naffah-Mazzacoratti MG et al.:
Selective alterations of glycosaminoglycans synthesis and proteoglycan expression in rat cortex and hippocampus in pilocarpine-induced epilepsy
Brain Res. Bull.
1999
50: 229-239
|
| 9865854 |
Garrido YC et al.:
Mitogen-activated protein kinase is increased in the limbic structures of the rat brain during the early stages of status epilepticus
Brain Res. Bull.
1998
47: 223-229
|
| 10366005 |
Naffah-Mazzacoratti MG et al.:
Growth-associated phosphoprotein expression is increased in the supragranular regions of the dentate gyrus following pilocarpine-induced seizures in rats.
Neuroscience
1999
91: 485-492
|
| 15987266 |
Longo B et al.:
Growth-associated protein 43 expression in hippocampal molecular layer of chronic epileptic rats treated with cycloheximide.
Epilepsia
2005
46: 125-128
|
| 17292888 |
Hanaya R et al.:
Dissociation of the immunoreactivity of synaptophysin and GAP-43 during the acute and latent phases of the lithium-pilocarpine model in the immature and adult rat.
Exp. Neurol.
2007
204: 720-732
|
| 18488994 |
Lively S et al.:
The extracellular matrix protein SC1/hevin localizes to excitatory synapses following status epilepticus in the rat lithium-pilocarpine seizure model.
J. Neurosci. Res.
2008
86: 2895-2905
|
| 17628511 |
Lively S et al.:
Analysis of the extracellular matrix protein SC1 during reactive gliosis in the rat lithium-pilocarpine seizure model
Brain Res.
2007
1163: 1-9
|
| 8774942 |
McNamara RK et al.:
NMDA receptor blockade prevents kainate induction of protein F1/GAP-43 mRNA in hippocampal granule cells and subsequent mossy fiber sprouting in the rat.
Brain Res. Mol. Brain Res.
1995
33: 22-28
|
| 17645533 |
Marchi N et al.:
In vivo and in vitro effects of pilocarpine: relevance to ictogenesis
Epilepsia
2007
48: 1934-1946
|
| 19320047 |
Marcon J et al.:
Age-dependent vascular changes induced by status epilepticus in rat forebrain: implications for epileptogenesis
Neurobiol. Dis.
2009
34: 121-132
|
| 19951488 |
Wang HP et al.:
[Effects of edaravone on the expression of interleukin-1beta, nuclear factor-kappaB and neuron apoptosis in juvenile rat hippocampus after status convulsion]
Zhonghua Er Ke Za Zhi
2009
47: 575-580
|
| 20149694 |
Liu J et al.:
Oxidative stress mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus
Seizure
2010
19: 165-172
|
| 19055492 |
Kuteykin-Teplyakov K et al.:
Complex time-dependent alterations in the brain expression of different drug efflux transporter genes after status epilepticus
Epilepsia
2009
50: 887-897
|
| 7491714 |
Mody I et al.:
NMDA receptor-dependent excitotoxicity: the role of intracellular Ca2+ release.
Trends Pharmacol. Sci.
1995
16: 356-359
|
| 15571975 |
Voutsinos-Porche B et al.:
Temporal patterns of the cerebral inflammatory response in the rat lithium-pilocarpine model of temporal lobe epilepsy.
Neurobiol. Dis.
2004
17: 385-402
|
| 20542576 |
Fabene PF et al.:
The emerging role for chemokines in epilepsy
J. Neuroimmunol.
2010
224: 22-27
|
| 19029985 |
et al.:
A role for leukocyte-endothelial adhesion mechanisms in epilepsy
Nat. Med.
2008
14: 1377-1383
|
| 21219330 |
Waldbaum S et al.:
Persistent impairment of mitochondrial and tissue redox status during lithium-pilocarpine-induced epileptogenesis
J. Neurochem.
2010
115: 1172-1182
|
| 20206232 |
Lin Y et al.:
Mitochondrial base excision repair pathway failed to respond to status epilepticus induced by pilocarpine.
Neurosci. Lett.
2010
474: 22-25
|
| 20732386 |
Pestana RR et al.:
Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy.
Neurosci. Lett.
2010
484: 187-191
|
| 19178557 |
Chuang YC et al.:
Contribution of nitric oxide, superoxide anion, and peroxynitrite to activation of mitochondrial apoptotic signaling in hippocampal CA3 subfield following experimental temporal lobe status epilepticus
Epilepsia
2009
50: 731-746
|
| 20155797 |
Chuang YC et al.:
Transcriptional upregulation of nitric oxide synthase II by nuclear factor-kappaB promotes apoptotic neuronal cell death in the hippocampus following experimental status epilepticus
J. Neurosci. Res.
2010
88: 1898-1907
|
| 30823590 |
Chuang YC et al.:
Resveratrol Promotes Mitochondrial Biogenesis and Protects against Seizure-Induced Neuronal Cell Damage in the Hippocampus Following Status Epilepticus by Activation of the PGC-1alpha Signaling Pathway
|
| 17360923 |
Choi YS et al.:
Status epilepticus-induced somatostatinergic hilar interneuron degeneration is regulated by striatal enriched protein tyrosine phosphatase
J. Neurosci.
2007
27: 2999-3009
|
| 19815358 |
Ishii A et al.:
Positive association between benign familial infantile convulsions and LGI4
Brain Dev.
2010
32: 538-543
|
| 19757204 |
Feng G et al.:
Down-regulation synaptic vesicle protein 2A in the anterior temporal neocortex of patients with intractable epilepsy.
J. Mol. Neurosci.
2009
39: 354-359
|
| 19803210 |
Savina TA et al.:
[Single audiogenic seizure promotes the increased levels of calcineurin and Ca(2+)-calmodulin-dependent protein kinase II in the rat brain]
Ross Fiziol Zh Im I M Sechenova
2009
95: 813-819
|
| 19633980 |
Haas CA et al.:
Reelin deficiency causes granule cell dispersion in epilepsy
Exp Brain Res
2010
200: 141-149
|
| 18186018 |
Liu XY et al.:
Comparative proteomics and correlated signaling network of rat hippocampus in the pilocarpine model of temporal lobe epilepsy.
Proteomics
2008
8: 582-603
|
| 17515952 |
Lee TS et al.:
Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes.
Mol. Med.
2007
13: 1-13
|
| 11312263 |
Gentil BJ et al.:
The giant protein AHNAK is a specific target for the calcium- and zinc-binding S100B protein: potential implications for Ca2+ homeostasis regulation by S100B
J. Biol. Chem.
2001
276
|
| 10913138 |
Deloulme JC et al.:
S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo
J. Biol. Chem.
2000
275
|
| 10510252 |
Garbuglia M et al.:
The calcium-modulated proteins, S100A1 and S100B, as potential regulators of the dynamics of type III intermediate filaments
Braz. J. Med. Biol. Res.
1999
32: 1177-1185
|
| 12354302 |
Li J et al.:
SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production
J. Neurochem.
2002
82: 1540-1548
|
| 12223485 |
Lammich S et al.:
Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide.
J. Biol. Chem.
2002
277
|
| 10950950 |
Kawashima H et al.:
Binding of a large chondroitin sulfate/dermatan sulfate proteoglycan, versican, to L-selectin, P-selectin, and CD44
J. Biol. Chem.
2000
275
|
| 9117263 |
Grumet M et al.:
Functions of brain chondroitin sulfate proteoglycans during developments: interactions with adhesion molecules
Perspect Dev Neurobiol
1996
3: 319-330
|
| 7512960 |
Grumet M et al.:
Interactions with tenascin and differential effects on cell adhesion of neurocan and phosphacan, two major chondroitin sulfate proteoglycans of nervous tissue
J. Biol. Chem.
1994
269
|
| 18295190 |
Pacheco Otalora LF et al.:
Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy.
Brain Res.
2008
1200: 116-131
|
| 11382382 |
Raza M et al.:
Long-term alteration of calcium homeostatic mechanisms in the pilocarpine model of temporal lobe epilepsy.
Brain Res.
2001
903: 1-12
|
| 20133704 |
Mazzuferi M et al.:
Enhancement of GABA(A)-current run-down in the hippocampus occurs at the first spontaneous seizure in a model of temporal lobe epilepsy
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 3180-3185
|
| 12242104 |
Perosa SR et al.:
Glycosaminoglycan levels and proteoglycan expression are altered in the hippocampus of patients with mesial temporal lobe epilepsy.
Brain Res. Bull.
2002
58: 509-516
|
| 17925172 |
Xiao F et al.:
[Overexpression of the Cdc42 in the brain tissue of human with intractable temporal epilepsy]
Zhonghua Yi Xue Za Zhi
2007
87: 2030-2032
|
| 19845729 |
Kirkman NJ et al.:
Innate but not adaptive immune responses contribute to behavioral seizures following viral infection
Epilepsia
2010
51: 454-464
|
| 18952671 |
Balosso S et al.:
A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1beta
Brain
2008
131: 3256-3265
|
| 20663517 |
Yang T et al.:
Why mesial temporal lobe epilepsy with hippocampal sclerosis is progressive: uncontrolled inflammation drives disease progression?
J. Neurol. Sci.
2010
296: 1-6
|
| 19850449 |
Waldbaum S et al.:
Mitochondria, oxidative stress, and temporal lobe epilepsy
Epilepsy Res.
2010
88: 23-45
|
| 18295498 |
Jarrett SG et al.:
Mitochondrial DNA damage and impaired base excision repair during epileptogenesis.
Neurobiol. Dis.
2008
30: 130-138
|
| 8293196 |
Meldrum BS et al.:
Excitotoxicity and selective neuronal loss in epilepsy.
Brain Pathol.
1993
3: 405-412
|
| 10531538 |
Blumcke I et al.:
Cellular pathology of hilar neurons in Ammons horn sclerosis.
J. Comp. Neurol.
1999
414: 437-453
|
| 11079540 |
Kunz WS et al.:
Mitochondrial complex I deficiency in the epileptic focus of patients with temporal lobe epilepsy.
Ann. Neurol.
2000
48: 766-773
|
| 16361082 |
Kubota H et al.:
Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis
Epilepsy Res.
2006
68: 213-228
|
| 26941603 |
Korn MJ et al.:
Conditional Disabled-1 Deletion in Mice Alters Hippocampal Neurogenesis and Reduces Seizure Threshold
Front Neurosci
2016
10: 63
|
| 15937479 |
Du W et al.:
Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder
Nat. Genet.
2005
37: 733-738
|
| 17522105 |
Puffenberger EG et al.:
Polyhydramnios, megalencephaly and symptomatic epilepsy caused by a homozygous 7-kilobase deletion in LYK5
Brain
2007
130: 1929-1941
|
| 20921534 |
Gardet A et al.:
LRRK2 is involved in the IFN-gamma response and host response to pathogens
J. Immunol.
2010
185: 5577-5585
|
| 17174426 |
Bialecka M et al.:
CARD15 variants in patients with sporadic Parkinsons disease
Neurosci. Res.
2007
57: 473-476
|
| 17237424 |
Moschen AR et al.:
Visfatin, an adipocytokine with proinflammatory and immunomodulating properties
J. Immunol.
2007
178: 1748-1758
|
| 24935928 |
Lin L et al.:
Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function
J. Immunol.
2014
193: 940-949
|
| 17005562 |
Yamamoto-Furusho JK et al.:
Centaurin beta1 down-regulates nucleotide-binding oligomerization domains 1- and 2-dependent NF-kappaB activation
J. Biol. Chem.
2006
281
|
| 23512405 |
Verma N et al.:
Profiling of ABC transporters during active ulcerative colitis and in vitro effect of inflammatory modulators
Dig. Dis. Sci.
2013
58: 2282-2292
|
| 11385576 |
Hugot JP et al.:
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohns disease
Nature
2001
411: 599-603
|
| 11385577 |
Ogura Y et al.:
A frameshift mutation in NOD2 associated with susceptibility to Crohns disease
Nature
2001
411: 603-606
|
| 23709157 |
Lin Z et al.:
NOD2 mutations affect muramyl dipeptide stimulation of human B lymphocytes and interact with other IBD-associated genes
Dig. Dis. Sci.
2013
58: 2599-2607
|
| 24572142 |
author information missing
article information missing
|
| 24739633 |
Ostvik AE et al.:
Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease
Inflamm. Bowel Dis.
2014
20: 995-1003
|
| 22672874 |
Dohi T et al.:
The TWEAK/Fn14 pathway as an aggravating and perpetuating factor in inflammatory diseases: focus on inflammatory bowel diseases
J. Leukoc. Biol.
2012
92: 265-279
|
| 21677747 |
Khor B et al.:
Genetics and pathogenesis of inflammatory bowel disease
Nature
2011
474: 307-317
|
| 20338925 |
Lu F et al.:
The role of the complement and contact systems in the dextran sulfate sodium-induced colitis model: the effect of C1 inhibitor in inflammatory bowel disease
Am. J. Physiol. Gastrointest. Liver Physiol.
2010
298: G878-G883
|
| 23329887 |
Shen J et al.:
Up-regulation and pre-activation of TRAF3 and TRAF5 in inflammatory bowel disease
Int J Med Sci
2013
10: 156-163
|
| 24137163 |
Zhong Y et al.:
Functions of NOD-Like Receptors in Human Diseases
Front Immunol
2013
4: 333
|
| 24740681 |
Zambetti LP et al.:
NLRPs, microbiota, and gut homeostasis: unravelling the connection
J. Pathol.
2014
233: 321-330
|
| 26287588 |
Rocha JD et al.:
LRRK2 and Nod2 promote lysozyme sorting in Paneth cells
Nat. Immunol.
2015
16: 898-900
|
| 28472257 |
Feldbrugge L et al. et al.:
Expression of Ecto-nucleoside Triphosphate Diphosphohydrolases-2 and -3 in the Enteric Nervous System Affects Inflammation in Experimental Colitis and Crohns Disease
J Crohns Colitis
2017
11: 1113-1123
|
| 23959882 |
Vandenbeuch A et al.:
Role of the ectonucleotidase NTPDase2 in taste bud function
Proc. Natl. Acad. Sci. U.S.A.
2013
110
|
| 27869326 |
author information missing
article information missing
|
| 29273328 |
author information missing
article information missing
|
| 19637336 |
Hong SK et al.:
Increased serum levels of L-arginine in ulcerative colitis and correlation with disease severity
Inflamm. Bowel Dis.
2010
16: 105-111
|
| 19023031 |
Okamoto R et al.:
Requirement of Notch activation during regeneration of the intestinal epithelia
Am. J. Physiol. Gastrointest. Liver Physiol.
2009
296: G23-G35
|
| 26604430 |
Senhaji N et al.:
Genetic Polymorphisms of Multidrug Resistance Gene-1 (MDR1/ABCB1) and Glutathione S-Transferase Gene and the Risk of Inflammatory Bowel Disease among Moroccan Patients
Mediators Inflamm.
2015
2015
|
| 27168239 |
Peloquin JM et al.:
Mechanisms of Pediatric Inflammatory Bowel Disease
Annu. Rev. Immunol.
2016
34: 31-64
|
| 24072822 |
Shan M et al.:
Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals
Science
2013
342: 447-453
|
| 24781901 |
Tong M et al.:
Reprograming of gut microbiome energy metabolism by the FUT2 Crohns disease risk polymorphism
ISME J
2014
8: 2193-2206
|
| 20570966 |
McGovern DP et al.:
Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohns disease
Hum. Mol. Genet.
2010
19: 3468-3476
|
| 25636123 |
Sovran B et al.:
IL-22-STAT3 pathway plays a key role in the maintenance of ileal homeostasis in mice lacking secreted mucus barrier
Inflamm. Bowel Dis.
2015
21: 531-542
|
| 24385580 |
Murchie R et al.:
Protein tyrosine phosphatase sigma targets apical junction complex proteins in the intestine and regulates epithelial permeability
Proc. Natl. Acad. Sci. U.S.A.
2014
111: 693-698
|
| 25058236 |
Uhlig HH et al.:
The diagnostic approach to monogenic very early onset inflammatory bowel disease
Gastroenterology
2014
147: 990-1007
|
| 24291022 |
Sandahl TD et al.:
The lectin pathway of the complement system is downregulated in Crohns disease patients who respond to anti-TNF-alpha therapy
J Crohns Colitis
2014
8: 521-528
|
| 17682002 |
Kugathasan S et al.:
Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease
Gut
2007
56: 1696-1705
|
| 15654782 |
Mudter J et al.:
Activation pattern of signal transducers and activators of transcription (STAT) factors in inflammatory bowel diseases
Am. J. Gastroenterol.
2005
100: 64-72
|
| 23668802 |
Ostvik AE et al.:
Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2
Clin. Exp. Immunol.
2013
173: 502-511
|
| 23613889 |
Fattouh R et al.:
Rac2-deficiency leads to exacerbated and protracted colitis in response to Citrobacter rodentium infection
PLoS ONE
2013
8
|
| 21900546 |
Muise AM et al.:
NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2
Gut
2012
61: 1028-1035
|
| 24931457 |
Dhillon SS et al.:
Variants in nicotinamide adenine dinucleotide phosphate oxidase complex components determine susceptibility to very early onset inflammatory bowel disease
Gastroenterology
2014
147: 680-689
|
| 23071489 |
Dinu I et al.:
SNP-SNP interactions discovered by logic regression explain Crohns disease genetics
PLoS ONE
2012
7
|
| 20089077 |
Sugihara T et al.:
The increased mucosal mRNA expressions of complement C3 and interleukin-17 in inflammatory bowel disease
Clin. Exp. Immunol.
2010
160: 386-393
|
| 24687413 |
Mrowicki J et al.:
The role of polymorphisms of genes CXCL12/CXCR4 and MIF in the risk development IBD the Polish population
Mol. Biol. Rep.
2014
41: 4639-4652
|
| 27498708 |
Yang J et al.:
Elevated IL-23R Expression and Foxp3+Rorgt+ Cells in Intestinal Mucosa During Acute and Chronic Colitis
Med. Sci. Monit.
2016
22: 2785-2792
|
| 20861596 |
Wilson SP et al.:
Inflammasome-mediated autoinflammatory disorders
Postgrad Med
2010
122: 125-133
|
| 27158904 |
Lamas B et al.:
CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands
Nat. Med.
2016
22: 598-605
|
| 27687530 |
Zhang Q et al.:
Wip 1 inhibits intestinal inflammation in inflammatory bowel disease
|
| 17764675 |
Nguyen DD et al.:
Lymphocyte-dependent and Th2 cytokine-associated colitis in mice deficient in Wiskott-Aldrich syndrome protein
Gastroenterology
2007
133: 1188-1197
|
| 23820270 |
Nguyen DD et al.:
Colitis and colon cancer in WASP-deficient mice require helicobacter species
Inflamm. Bowel Dis.
2013
19: 2041-2050
|
| 26604638 |
Bianco AM et al.:
Genetics of inflammatory bowel disease from multifactorial to monogenic forms
World J. Gastroenterol.
2015
21
|
| 18758464 |
Kugathasan S et al.:
Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease
Nat. Genet.
2008
40: 1211-1215
|
| 19453248 |
Van Limbergen J et al.:
The genetics of Crohns disease
Annu Rev Genomics Hum Genet
2009
10: 89-116
|
| 22377701 |
Yu W et al.:
PTPN2 is associated with Crohns disease and its expression is regulated by NKX2-3
Dis. Markers
2012
32: 83-91
|
| 24980432 |
Chahar S et al.:
Chromatin profiling reveals regulatory network shifts and a protective role for hepatocyte nuclear factor 4alpha during colitis
Mol. Cell. Biol.
2014
34: 3291-3304
|
| 26078663 |
Beser OF et al.:
Association of familial Mediterranean fever in Turkish children with inflammatory bowel disease
Turk Pediatri Ars
2014
49: 198-202
|
| 24247223 |
Baxt LA et al.:
Role of Autophagy in the Maintenance of Intestinal Homeostasis
Gastroenterology
2015
149: 553-562
|
| 21252204 |
Fritz T et al.:
Crohns disease: NOD2, autophagy and ER stress converge
Gut
2011
60: 1580-1588
|
| 21425313 |
Janse M et al.:
Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9
Hepatology
2011
53: 1977-1985
|
| 24971461 |
Bank S et al.:
Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are associated with susceptibility of inflammatory bowel disease in a Danish cohort
PLoS ONE
2014
9
|
| 17361131 |
Nenci A et al.:
Epithelial NEMO links innate immunity to chronic intestinal inflammation
Nature
2007
446: 557-561
|
| 15753535 |
Andresen L et al.:
Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis
Gut
2005
54: 503-509
|
| 27104830 |
Coburn LA et al.:
L-Arginine Availability and Metabolism Is Altered in Ulcerative Colitis
Inflamm. Bowel Dis.
2016
22: 1847-1858
|
| 24430113 |
Dhillon SS et al.:
Higher activity of the inducible nitric oxide synthase contributes to very early onset inflammatory bowel disease
Clin Transl Gastroenterol
2014
5: E46
|
| 22445837 |
Ciccacci C et al.:
TRAF3IP2 gene is associated with cutaneous extraintestinal manifestations in inflammatory bowel disease
J Crohns Colitis
2013
7: 44-52
|
| 26836588 |
Li Q et al.:
Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease
Gastroenterology
2016
150: 1196-1207
|
| 23414308 |
author information missing
article information missing
|
| 26953272 |
et al.:
|
| 22607974 |
author information missing
article information missing
|
| 15842589 |
author information missing
article information missing
|
| 19898471 |
author information missing
article information missing
|
| 24092863 |
author information missing
article information missing
|
| 19098911 |
author information missing
article information missing
|
| 21287672 |
et al.:
|
| 27050757 |
Laubitz D et al.:
Reduced Epithelial Na+/H+ Exchange Drives Gut Microbial Dysbiosis and Promotes Inflammatory Response in T Cell-Mediated Murine Colitis
PLoS ONE
2016
11
|
| 15362034 |
Bassaganya-Riera J et al.:
Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease
Gastroenterology
2004
127: 777-791
|
| 27656050 |
Bryan PF et al.:
Sphingolipids as Mediators in the Crosstalk between Microbiota and Intestinal Cells: Implications for Inflammatory Bowel Disease
Mediators Inflamm.
2016
2016
|
| 27609529 |
Kolho KL et al.:
Faecal and Serum Metabolomics in Paediatric Inflammatory Bowel Disease
J Crohns Colitis
2017
11: 321-334
|
| 29358413 |
Bowser JL et al.:
The Hypoxia-Adenosine Link during Intestinal Inflammation
J. Immunol.
2018
200: 897-907
|
| 30257633 |
White LS et al.:
The gut microbiota: cause and cure of gut diseases
Med. J. Aust.
2018
209: 312-317
|
| 29404503 |
Peng ZW et al.:
The ectonucleotidase ENTPD1/CD39 limits biliary injury and fibrosis in mouse models of sclerosing cholangitis
Hepatol Commun
2017
1: 957-972
|
| 23241884 |
Kusu T et al. et al.:
Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestine
J. Immunol.
2013
190: 774-783
|
| 23338058 |
author information missing
Extracellular adenosine signaling in molecular medicine
J. Mol. Med.
2013
91: 141-146
|
| 27517910 |
Kang K et al.:
A Genome-Wide Methylation Approach Identifies a New Hypermethylated Gene Panel in Ulcerative Colitis
|
| 30488796 |
Triantafyllou C et al.:
Endothelial and Cardiac Dysfunction in Inflammatory Bowel Diseases: Does Treatment Modify the Inflammatory Load on Arterial and Cardiac Structure and Function?
|
| 24417819 |
Avitzur Y et al. et al.:
Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease
Gastroenterology
2014
146: 1028-1039
|
| 22271508 |
Wei SC et al.:
Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling
Inflamm. Bowel Dis.
2012
18: 877-888
|
| 32178720 |
Lopens S et al.:
The search for the Holy Grail: autoantigenic targets in primary sclerosing cholangitis associated with disease phenotype and neoplasia
Auto Immun Highlights
2020
11: 6
|
| 32508154 |
Zabana Y et al. et al.:
Transcriptomic identification of TMIGD1 and its relationship with the ileal epithelial cell differentiation in Crohns disease
|
| 31649195 |
Lu Y et al. et al.:
Palmitoylation of NOD1 and NOD2 is required for bacterial sensing
Science
2019
366: 460-467
|
| 28490634 |
Buzza MS et al.:
Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis
J. Biol. Chem.
2017
292
|
| 22837003 |
Hashimoto T et al. et al.:
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
Nature
2012
487: 477-481
|
| 31409604 |
Garg M et al. et al.:
Imbalance of the renin-angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target?
Gut
2020
69: 841-851
|
| 29155324 |
Yisireyili M et al.:
Angiotensin receptor blocker irbesartan reduces stress-induced intestinal inflammation via AT1a signaling and ACE2-dependent mechanism in mice
Brain Behav Immun
2018
69: 167-179
|
| 18440672 |
Crenn P et al.:
Citrulline as a biomarker of intestinal failure due to enterocyte mass reduction
Clin Nutr
2008
27: 328-339
|
| 20224991 |
Kato Y et al. et al.:
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1
Pharm Res
2010
27: 832-840
|
| 15107849 |
Peltekova VD et al. et al.:
Functional variants of OCTN cation transporter genes are associated with Crohn disease
Nat Genet
2004
36: 471-475
|
| 15795384 |
Grundemann D et al.:
Discovery of the ergothioneine transporter
Proc Natl Acad Sci U S A
2005
102: 5256-5261
|
| 19834971 |
author information missing
article information missing
|
| 29452228 |
author information missing
article information missing
|
| 28423340 |
author information missing
article information missing
|
| 23634226 |
author information missing
article information missing
|
| 34997981 |
author information missing
article information missing
|
| 24727021 |
author information missing
article information missing
|
| 23949622 |
author information missing
article information missing
|
| 35398597 |
author information missing
article information missing
|
| 19942298 |
Zhang F et al.:
Peroxisome proliferator-activated receptor-gamma agonists suppress iNOS expression induced by LPS in rat primary Schwann cells
J. Neuroimmunol.
2010
218: 36-47
|
| 18626576 |
Solt LA et al.:
The IkappaB kinase complex: master regulator of NF-kappaB signaling
Immunol. Res.
2008
42: 3-18
|
| 20501748 |
Condamine T et al.:
Tmem176B and Tmem176A are associated with the immature state of dendritic cells
J. Leukoc. Biol.
2010
88: 507-515
|
| 23509351 |
Becker HM et al.:
alpha1beta1 integrin-mediated adhesion inhibits macrophage exit from a peripheral inflammatory lesion
J. Immunol.
2013
190: 4305-4314
|
| 21737776 |
McElroy SJ et al.:
Tumor necrosis factor receptor 1-dependent depletion of mucus in immature small intestine: a potential role in neonatal necrotizing enterocolitis
Am. J. Physiol. Gastrointest. Liver Physiol.
2011
301: G656-G666
|
| 17385041 |
Vilkin A et al.:
Gallbladder inflammation is associated with increase in mucin expression and pigmented stone formation
Dig. Dis. Sci.
2007
52: 1613-1620
|
| 25623068 |
Layne JD et al.:
Ectopically expressed pro-group X secretory phospholipase A2 is proteolytically activated in mouse adrenal cells by furin-like proprotein convertases: implications for the regulation of adrenal steroidogenesis
J. Biol. Chem.
2015
290: 7851-7860
|
| 25468720 |
Golebiewska EM et al.:
Platelet secretion: From haemostasis to wound healing and beyond
Blood Rev.
2015
29: 153-162
|
| 18729074 |
Brown KA et al.:
Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1
J. Cell. Biochem.
2008
105: 596-611
|
| 25928368 |
Ren Y et al.:
TGFbeta-1 and TGFBR2 polymorphisms, cooking oil fume exposure and risk of lung adenocarcinoma in Chinese nonsmoking females: a case control study
BMC Med. Genet.
2015
16: 22
|
| 11087742 |
Ogura Y et al.:
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB
J. Biol. Chem.
2001
276: 4812-4818
|
| 25512380 |
Culp DJ et al.:
Salivary mucin 19 glycoproteins: innate immune functions in Streptococcus mutans-induced caries in mice and evidence for expression in human saliva
J. Biol. Chem.
2015
290: 2993-3008
|
| 15097436 |
Shaoul R et al.:
Colonic expression of MUC2, MUC5AC, and TFF1 in inflammatory bowel disease in children
J. Pediatr. Gastroenterol. Nutr.
2004
38: 488-493
|
| 25274297 |
Pickard JM et al.:
Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness
Nature
2014
514: 638-641
|
| 15958416 |
Hurd EA et al.:
Gastrointestinal mucins of Fut2-null mice lack terminal fucosylation without affecting colonization by Candida albicans
Glycobiology
2005
15: 1002-1007
|
| 24248342 |
Glover LE et al.:
Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis
Proc. Natl. Acad. Sci. U.S.A.
2013
110
|
| 17517660 |
Oliveira JB et al.:
NRAS mutation causes a human autoimmune lymphoproliferative syndrome
Proc. Natl. Acad. Sci. U.S.A.
2007
104: 8953-8958
|
| 16007086 |
Castigli E et al.:
TACI is mutant in common variable immunodeficiency and IgA deficiency
Nat. Genet.
2005
37: 829-834
|
| 21881205 |
Kitamura A et al.:
A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans
J. Clin. Invest.
2011
121: 4150-4160
|
| 12530983 |
Badour K et al.:
The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse
Immunity
2003
18: 141-154
|
| 21079152 |
Niemela JE et al.:
Somatic KRAS mutations associated with a human nonmalignant syndrome of autoimmunity and abnormal leukocyte homeostasis
Blood
2011
117: 2883-2886
|
| 17187069 |
Hsu YM et al.:
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens
Nat. Immunol.
2007
8: 198-205
|
| 22983707 |
Glasmacher E et al.:
A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes
Science
2012
338: 975-980
|
| 15870263 |
Reiley W et al.:
Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation
Mol. Cell. Biol.
2005
25: 3886-3895
|
| 22547678 |
Marinis JM et al.:
IkappaB kinase alpha phosphorylation of TRAF4 downregulates innate immune signaling
Mol. Cell. Biol.
2012
32: 2479-2489
|
| 10421844 |
et al.:
|
| 26561545 |
Heiseke AF et al.:
IRAK1 Drives Intestinal Inflammation by Promoting the Generation of Effector Th Cells with Optimal Gut-Homing Capacity
J. Immunol.
2015
195: 5787-5794
|
| 26376209 |
Wan Q et al.:
The miR-30a Negatively Regulates IL-17-Mediated Signal Transduction by Targeting Traf3ip2
J. Interferon Cytokine Res.
2015
35: 917-923
|
| 19575028 |
Gaffen SL et al.:
Structure and signalling in the IL-17 receptor family
Nat. Rev. Immunol.
2009
9: 556-567
|
| 23557798 |
Song X et al.:
The activation and regulation of IL-17 receptor mediated signaling
Cytokine
2013
62: 175-182
|
| 16085473 |
Petrilli V et al.:
The inflammasome
Curr. Biol.
2005
15: R581
|
| 9045686 |
Vincenz C et al.:
Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling
J. Biol. Chem.
1997
272: 6578-6583
|
| 26792751 |
Forlani G et al.:
The Major Histocompatibility Complex Class II Transactivator CIITA Inhibits the Persistent Activation of NF-kappaB by the Human T Cell Lymphotropic Virus Type 1 Tax-1 Oncoprotein
J. Virol.
2016
90: 3708-3721
|
| 21651891 |
Yu S et al.:
Identification of tripartite motif-containing 22 (TRIM22) as a novel NF-kappaB activator
Biochem. Biophys. Res. Commun.
2011
410: 247-251
|
| 19265157 |
Yang K et al.:
TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response
J. Immunol.
2009
182: 3782-3792
|
| 21628460 |
Ryu YS et al.:
TRIM32 protein sensitizes cells to tumor necrosis factor (TNFalpha)-induced apoptosis via its RING domain-dependent E3 ligase activity against X-linked inhibitor of apoptosis (XIAP)
J. Biol. Chem.
2011
286
|
| 19675569 |
author information missing
article information missing
|
| 15125833 |
author information missing
article information missing
|
| 19667203 |
et al.:
|
| 12089335 |
author information missing
article information missing
|
| 11525169 |
author information missing
article information missing
|
| 11460167 |
author information missing
article information missing
|
| 9177220 |
author information missing
article information missing
|
| 26670046 |
author information missing
article information missing
|
| 27591049 |
author information missing
article information missing
|
| 12023369 |
author information missing
article information missing
|
| 11114383 |
author information missing
article information missing
|
| 15030775 |
Agostini L et al.:
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
Immunity
2004
3: 319-325
|
| 27043286 |
author information missing
article information missing
|
| 22743999 |
Leitch AE et al.:
Cyclin-dependent kinases 7 and 9 specifically regulate neutrophil transcription and their inhibition drives apoptosis to promote resolution of inflammation
Cell Death Differ.
2012
19: 1950-1961
|
| 16227999 |
et al.:
|
| 22074829 |
Hasegawa H et al.:
Lysophosphatidylcholine enhances the suppressive function of human naturally occurring regulatory T cells through TGF-beta production
Biochem. Biophys. Res. Commun.
2011
415: 526-531
|
| 18815221 |
author information missing
article information missing
|
| 23180825 |
Nagahashi M et al.:
Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network
FASEB J.
2013
27: 1001-1011
|
| 22723910 |
Hisano Y et al.:
Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells
PLoS ONE
2012
7
|
| 12091396 |
Liu L et al.:
The GTPase Rap1 regulates phorbol 12-myristate 13-acetate-stimulated but not ligand-induced beta 1 integrin-dependent leukocyte adhesion
J. Biol. Chem.
2002
277
|
| 23345459 |
Muller WA et al.:
Getting leukocytes to the site of inflammation
Vet. Pathol.
2013
50: 7-22
|
| 26059755 |
Zhang H et al.:
ZC3H12D attenuated inflammation responses by reducing mRNA stability of proinflammatory genes
Mol. Immunol.
2015
67: 206-212
|
| 26458764 |
Chen WD et al.:
Circadian CLOCK Mediates Activation of Transforming Growth Factor-beta Signaling and Renal Fibrosis through Cyclooxygenase 2
Am. J. Pathol.
2015
185: 3152-3163
|
| 26432841 |
Ingle KA et al.:
Cardiomyocyte-specific Bmal1 deletion in mice triggers diastolic dysfunction, extracellular matrix response, and impaired resolution of inflammation
Am. J. Physiol. Heart Circ. Physiol.
2015
309
|
| 27251625 |
Goeden N et al.:
Maternal Inflammation Disrupts Fetal Neurodevelopment via Increased Placental Output of Serotonin to the Fetal Brain
J. Neurosci.
2016
36: 6041-6049
|
| 9971870 |
Gabay C et al.:
Acute-phase proteins and other systemic responses to inflammation
N. Engl. J. Med.
1999
340: 448-454
|
| 15306172 |
Khovidhunkit W et al.:
Apolipoproteins A-IV and A-V are acute-phase proteins in mouse HDL
Atherosclerosis
2004
176: 37-44
|
| 7682067 |
Sellar GC et al.:
Characterization and acute phase modulation of canine apolipoprotein H (beta 2-glycoprotein I)
Biochem. Biophys. Res. Commun.
1993
191: 1288-1293
|
| 9350999 |
Lacorte JM et al.:
Repression of apoC-III gene expression by TNFalpha involves C/EBPdelta/NF-IL6beta via an IL-1 independent pathway
FEBS Lett.
1997
415: 217-220
|
| 18497424 |
Li L et al.:
Infection induces a positive acute phase apolipoprotein E response from a negative acute phase gene: role of hepatic LDL receptors
J. Lipid Res.
2008
49: 1782-1793
|
| 27485016 |
Lee JH et al.:
Small heterodimer partner SHP mediates liver X receptor (LXR)-dependent suppression of inflammatory signaling by promoting LXR SUMOylation specifically in astrocytes
Sci Signal
2016
9: RA78
|
| 26216936 |
Slone EA et al.:
Phospholipid scramblase 1 is required for beta2-glycoprotein I binding in hypoxia and reoxygenation-induced endothelial inflammation
J. Leukoc. Biol.
2015
98: 791-804
|
| 10601648 |
Isumi Y et al.:
Adrenomedullin suppresses interleukin-1beta-induced tumor necrosis factor-alpha production in Swiss 3T3 cells
FEBS Lett.
1999
463: 110-114
|
| 26779180 |
Krystel-Whittemore M et al.:
Mast Cell: A Multi-Functional Master Cell
Front Immunol
2016
6: 620
|
| 15953541 |
Li K et al.:
Identification and expression of a new type II transmembrane protein in human mast cells
Genomics
2005
86: 68-75
|
| 17174561 |
Ramana KV et al.:
Mediation of aldose reductase in lipopolysaccharide-induced inflammatory signals in mouse peritoneal macrophages
Cytokine
2006
36: 115-122
|
| 14561216 |
Odom DT et al.:
Control of pancreas and liver gene expression by HNF transcription factors
Science
2004
303: 1378-1381
|
| 1748314 |
Mehdi H et al.:
Nucleotide sequence and expression of the human gene encoding apolipoprotein H (beta 2-glycoprotein I)
Gene
1991
108: 293-298
|
| 11556518 |
Ruminy P et al.:
Gene transcription in hepatocytes during the acute phase of a systemic inflammation: from transcription factors to target genes
Inflamm. Res.
2001
50: 383-390
|
| 8034668 |
Healy AM et al.:
Induction of plasminogen activator inhibitor-1 in HepG2 human hepatoma cells by mediators of the acute phase response
J. Biol. Chem.
1994
269
|
| 19836472 |
Cummins TD et al.:
Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling
Biochim. Biophys. Acta
2010
1804: 653-661
|
| 8995379 |
Trub T et al.:
The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signaling
J. Biol. Chem.
1997
272: 894-902
|
| 2482266 |
Okamoto H et al.:
Acute-phase response of angiotensinogen in rat adjuvant arthritis
Int J Tissue React
1989
11: 123-127
|
| 21430962 |
Jain S et al.:
Acute-phase proteins: As diagnostic tool
J Pharm Bioallied Sci
2011
3: 118-127
|
| 18039467 |
Liu Z et al.:
Fibrinogen-like protein 1, a hepatocyte derived protein is an acute phase reactant
Biochem. Biophys. Res. Commun.
2008
365: 729-734
|
| 15758012 |
Weiss G et al.:
Anemia of chronic disease
N. Engl. J. Med.
2005
352: 1011-1023
|
| 2506062 |
Anthony R et al.:
Regulation of hepatic synthesis of C3 and C4 during the acute-phase response in the rat
Eur J Immunol
1989
19: 1405-1412
|
| 2409807 |
author information missing
The acute phase response of C3, C5, ceruloplasmin, and C-reactive protein induced by turpentine pleurisy in the rabbit
Am. J. Pathol.
1985
120: 146-156
|
| 28062222 |
Choubey D et al.:
Absent in Melanoma 2 proteins in SLE
Clin. Immunol.
2017
176: 42-48
|
| 24381786 |
Richards CD et al.:
The enigmatic cytokine oncostatin m and roles in disease
ISRN Inflamm
2013
2013
|
| 20088942 |
Rychli K et al.:
The inflammatory mediator oncostatin M induces angiopoietin 2 expression in endothelial cells in vitro and in vivo
J. Thromb. Haemost.
2010
8: 596-604
|
| 2464026 |
Marinkovic S et al.:
IL-6 modulates the synthesis of a specific set of acute phase plasma proteins in vivo
J. Immunol.
1989
142: 808-812
|
| 16368716 |
Zhang SX et al.:
Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor
FASEB J.
2006
20: 323-325
|
| 19136629 |
Weber S et al.:
PRMT1-mediated arginine methylation of PIAS1 regulates STAT1 signaling
Genes Dev.
2009
23: 118-132
|
| 17620405 |
Sun S et al.:
UXT is a novel and essential cofactor in the NF-kappaB transcriptional enhanceosome
J. Cell Biol.
2007
178: 231-244
|
| 22131337 |
Huang Y et al.:
UXT-V1 facilitates the formation of MAVS antiviral signalosome on mitochondria
J. Immunol.
2012
188: 358-366
|
| 21307340 |
Huang Y et al.:
UXT-V1 protects cells against TNF-induced apoptosis through modulating complex II formation
Mol. Biol. Cell
2011
22: 1389-1397
|
| 21435468 |
Jin Y et al.:
A novel function for programmed death ligand-1 regulation of angiogenesis
Am. J. Pathol.
2011
178: 1922-1929
|
| 18441324 |
Mori S et al.:
Direct binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signaling
J. Biol. Chem.
2008
283
|
| 29201045 |
Farup PG et al.:
Functional Bowel Disorders Are Associated with a Central Immune Activation
Gastroenterol Res Pract
2017
2017
|
| 28532421 |
El-Ansary A et al.:
Glutamate excitotoxicity induced by orally administered propionic acid, a short chain fatty acid can be ameliorated by bee pollen
Lipids Health Dis
2017
16: 96
|
| 22531301 |
El-Ansary AK et al.:
Etiology of autistic features: the persisting neurotoxic effects of propionic acid
J Neuroinflammation
2012
9: 74
|
| 29694888 |
Krishnan S et al.:
Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages
Cell Rep
2018
23: 1099-1111
|
| 22585093 |
Obayashi Y et al.:
Proline protects liver from D-galactosamine hepatitis by activating the IL-6/STAT3 survival signaling pathway
Amino Acids
2012
43: 2371-2380
|
| 30442802 |
Gentile CL et al.:
The gut microbiota at the intersection of diet and human health
Science
2018
362: 776-780
|
| 30385457 |
Abdel-Haq R et al.:
Microbiome-microglia connections via the gut-brain axis
J Exp Med
2019
216: 41-59
|
| 23928362 |
Michot C et al. et al.:
Combination of lipid metabolism alterations and their sensitivity to inflammatory cytokines in human lipin-1-deficient myoblasts
Biochim. Biophys. Acta
2013
1832: 2103-2114
|
| 22700961 |
Liu TF et al.:
NAD+-dependent sirtuin 1 and 6 proteins coordinate a switch from glucose to fatty acid oxidation during the acute inflammatory response
J. Biol. Chem.
2012
287
|
| 27920568 |
Zivkovic AR et al.:
Reduced butyrylcholinesterase activity is an early indicator of trauma-induced acute systemic inflammatory response
J Inflamm Res
2016
9: 221-230
|
| 25731162 |
Chassaing B et al.:
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
Nature
2015
519: 92-96
|
| 30577275 |
Tan L et al.:
miR-155 Aggravates Liver Ischemia/reperfusion Injury by Suppressing SOCS1 in Mice
Transplant. Proc.
2018
50: 3831-3839
|
| 26251957 |
Lv X et al.:
Inhibition of microRNA155 relieves sepsisinduced liver injury through inactivating the JAK/STAT pathway
Mol Med Rep
2015
12: 6013-6018
|
| 24262277 |
Yin H et al.:
Deletion of SIRT1 from hepatocytes in mice disrupts lipin-1 signaling and aggravates alcoholic fatty liver
Gastroenterology
2014
146: 801-811
|
| 28552621 |
Wellman AS et al. et al.:
Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota
Gastroenterology
2017
153: 772-786
|
| 24104551 |
Hasson RM et al.:
Estrogen receptor alpha or beta loss in the colon of Min/+ mice promotes crypt expansion and impairs TGFbeta and HNF3beta signaling
Carcinogenesis
2014
35: 96-102
|
| 28088611 |
Sun KY et al.:
Lactobacillus paracasei modulates LPS-induced inflammatory cytokine release by monocyte-macrophages via the up-regulation of negative regulators of NF-kappaB signaling in a TLR2-dependent manner
Cytokine
2017
92: 1-11
|
| 28232186 |
Shao J et al.:
Suv39h2 deficiency ameliorates diet-induced steatosis in mice
Biochem Biophys Res Commun
2017
485: 658-664
|
| 28244120 |
Fan Z et al.:
The histone methyltransferase Suv39h2 contributes to nonalcoholic steatohepatitis in mice
Hepatology
2017
65: 1904-1919
|
| 29465369 |
Araki Y et al.:
Altered gene expression profiles of histone lysine methyltransferases and demethylases in rheumatoid arthritis synovial fibroblasts
Clin Exp Rheumatol
2018
36: 314-316
|
| 30659595 |
Murayama Y et al. et al.:
Glucocorticoid receptor suppresses gene expression of Rev-erbalpha (Nr1d1) through interaction with the CLOCK complex
FEBS Lett.
2019
593: 423-432
|
| 16968709 |
Wang J et al.:
The orphan nuclear receptor Rev-erb alpha regulates circadian expression of plasminogen activator inhibitor type 1
J. Biol. Chem.
2006
281
|
| 28786289 |
Kriisa K et al.:
Profiling of Acylcarnitines in First Episode Psychosis before and after Antipsychotic Treatment
J. Proteome Res.
2017
16: 3558-3566
|
| 23636220 |
Yarwood A et al.:
Enrichment of vitamin D response elements in RA-associated loci supports a role for vitamin D in the pathogenesis of RA
Genes Immun.
2013
14: 325-329
|
| 22683764 |
Hughes MM et al.:
Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation
Brain Behav. Immun.
2012
26: 979-987
|
| 22929065 |
Elovainio M et al.:
Indoleamine 2,3-dioxygenase activation and depressive symptoms: results from the Young Finns Study
Psychosom Med
2012
74: 675-681
|
| 26173806 |
Schottker B et al.:
Discovery of a novel epigenetic cancer marker related to the oxidative status of human blood
Genes Chromosomes Cancer
2015
54: 583-594
|
| 23353556 |
LeBleu VS et al.:
Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis
Nat Med
2013
19: 227-231
|
| 23353556 |
LeBleu VS et al.:
Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis
Nat. Med.
2013
19: 227-231
|
| 24098382 |
Nau F Jr et al.:
Serotonin 5-HT2A receptor activation blocks TNF-alpha mediated inflammation in vivo
PLoS ONE
2013
8
|
| 28804270 |
Yin H et al.:
Knockdown of miR-155 protects microglia against LPS-induced inflammatory injury via targeting RACK1: a novel research for intracranial infection
J Inflamm (Lond)
2017
14: 17
|
| 26116897 |
Rajeevan MS et al.:
Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome
Hum. Immunol.
2015
76: 553-560
|
| 17266443 |
Tripal P et al.:
Unique features of different members of the human guanylate-binding protein family
J Interferon Cytokine Res
2007
27: 44-52
|
| 19729072 |
Goldenberg RC et al.:
Transcriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes
Microbes Infect
2009
11: 1140-1149
|
| 22567129 |
Vazquez-Cintron EJ et al.:
Protocadherin-18 is a novel differentiation marker and an inhibitory signaling receptor for CD8+ effector memory T cells
PLoS ONE
2012
7
|
| 26055709 |
Wood ER et al. et al.:
The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors
J. Biol. Chem.
2015
290
|
| 31544798 |
Ranjan A et al.:
Genetic underpinnings of lung function and COPD
|
| 29793924 |
Kanneganti A et al.:
GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever
J. Exp. Med.
2018
215: 1519-1529
|
| 18227059 |
Simon GM et al.:
Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain
J. Biol. Chem.
2008
283: 9341-9349
|
| 30804210 |
Kim SS et al.:
The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance interferon-beta response
J. Biol. Chem.
2019
294: 6430-6438
|
| 9182547 |
Harada N et al.:
Human IgGFc binding protein (FcgammaBP) in colonic epithelial cells exhibits mucin-like structure
J. Biol. Chem.
1997
272
|
| 28515150 |
Evankovich J et al.:
Receptor for advanced glycation end products is targeted by FBXO10 for ubiquitination and degradation
FASEB J.
2017
31: 3894-3903
|
| 29377137 |
Chua CEL et al.:
Rab 10-a traffic controller in multiple cellular pathways and locations
J. Cell. Physiol.
2018
233: 6483-6494
|
| 20028485 |
Cardoso CM et al.:
Rab10 regulates phagosome maturation and its overexpression rescues Mycobacterium-containing phagosomes maturation
Traffic
2010
11: 221-235
|
| 27267271 |
Li W et al.:
Esterase D enhances type I interferon signal transduction to suppress foot-and-mouth disease virus replication
Mol. Immunol.
2016
75: 112-121
|
| 10574717 |
McLaughlin F et al.:
Characterisation of the tumour necrosis factor (TNF)-(alpha) response elements in the human ICAM-2 promoter
J. Cell. Sci.
1999
112: ( Pt 24
|
| 28320969 |
Estin ML et al.:
Ena/VASP proteins regulate activated T-cell trafficking by promoting diapedesis during transendothelial migration
Proc. Natl. Acad. Sci. U.S.A.
2017
114
|
| 26797711 |
Spanjer AI et al. et al.:
A pro-inflammatory role for the Frizzled-8 receptor in chronic bronchitis
Thorax
2016
71: 312-322
|
| 28974614 |
Finethy R et al.:
Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins
|
| 32050049 |
Kusunose N et al.:
Circadian expression of Glycoprotein 2 (Gp2) gene is controlled by a molecular clock in mouse Peyers patches
|
| 22891285 |
Werner L et al.:
Identification of pancreatic glycoprotein 2 as an endogenous immunomodulator of innate and adaptive immune responses
J. Immunol.
2012
189: 2774-2783
|
| 27267461 |
Meng J et al.:
Rb selectively inhibits innate IFN-beta production by enhancing deacetylation of IFN-beta promoter through HDAC1 and HDAC8
J. Autoimmun.
2016
73: 42-53
|
| 29571125 |
Ma MW et al.:
NADPH oxidases in traumatic brain injury - Promising therapeutic targets?
Redox Biol
2018
16: 285-293
|
| 30873159 |
Lee N et al.:
Role of NFAT5 in the Immune System and Pathogenesis of Autoimmune Diseases
Front Immunol
2019
10: 270
|
| 30391952 |
Yang XL et al.:
NFAT5 Has a Job in the Brain
Dev. Neurosci.
2018
40: 289-300
|
| 26611359 |
Ran Y et al.:
Autoubiquitination of TRIM26 links TBK1 to NEMO in RLR-mediated innate antiviral immune response
J Mol Cell Biol
2016
8: 31-43
|
| 12968017 |
Xu Y et al.:
Interferon gamma repression of collagen (COL1A2) transcription is mediated by the RFX5 complex
J. Biol. Chem.
2003
278
|
| 31976312 |
Gao N et al.:
Metabonomic-Transcriptome Integration Analysis on Osteoarthritis and Rheumatoid Arthritis
Int J Genomics
2020
2020
|
| 29637127 |
Kulohoma BW et al.:
Peripheral blood RNA gene expression in children with pneumococcal meningitis: a prospective case-control study
BMJ Paediatr Open
2017
1
|
| 26331680 |
Nieto-Torres JL et al.:
Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome
Virology
2015
485: 330-339
|
| 29524262 |
Nakashima C et al.:
Interleukin-31 and interleukin-31 receptor: New therapeutic targets for atopic dermatitis
Exp. Dermatol.
2018
27: 327-331
|
| 27797811 |
Psachoulia K et al.:
IL4I1 augments CNS remyelination and axonal protection by modulating T cell driven inflammation
Brain
2016
139: 3121-3136
|
| 18579585 |
Morris VA et al.:
Activation of Akt through gp130 receptor signaling is required for Kaposis sarcoma-associated herpesvirus-induced lymphatic reprogramming of endothelial cells
J. Virol.
2008
82: 8771-8779
|
| 29802199 |
Ambrose RL et al.:
C6orf106 is a novel inhibitor of the interferon-regulatory factor 3-dependent innate antiviral response
J. Biol. Chem.
2018
293
|
| 11597948 |
Peng J et al.:
Alteration of platelet function in dogs mediated by interleukin-6
Blood
1994
83: 398-403
|
| 9437185 |
Neumann FJ et al.:
Effect of human recombinant interleukin-6 and interleukin-8 on monocyte procoagulant activity
Arterioscler. Thromb. Vasc. Biol.
1997
17: 3399-3405
|
| 2555368 |
Scarpati EM et al.:
Regulation of endothelial cell coagulant properties. Modulation of tissue factor, plasminogen activator inhibitors, and thrombomodulin by phorbol 12-myristate 13-acetate and tumor necrosis factor
J. Biol. Chem.
1989
264
|
| 28303603 |
Gao H et al.:
Human IL-6, IL-17, IL-1beta, and TNF-alpha differently regulate the expression of pro-inflammatory related genes, tissue factor, and swine leukocyte antigen class I in porcine aortic endothelial cells
|
| 31118448 |
Truong KL et al. et al.:
Killer-like receptors and GPR56 progressive expression defines cytokine production of human CD4(+) memory T cells
Nat Commun
2019
10: 2263
|
| 30397350 |
Povoleri GAM et al. et al.:
Human retinoic acid-regulated CD161(+) regulatory T cells support wound repair in intestinal mucosa
Nat. Immunol.
2018
19: 1403-1414
|
| 31133046 |
Marceau F et al.:
Increased fibrinolysis-induced bradykinin formation in hereditary angioedema confirmed using stored plasma and biotechnological inhibitors
BMC Res Notes
2019
12: 291
|
| 9034191 |
Moss ML et al. et al.:
Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha
Nature
1997
385: 733-736
|
| 23840373 |
Bergman P et al.:
Vitamin D and Respiratory Tract Infections: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
PLoS ONE
2013
8
|
| 32631435 |
author information missing
article information missing
|
| 32173150 |
Dai K et al.:
Leucine rich repeats and calponin homology domain containing 1 inhibits NK-92 cell cytotoxicity through attenuating Src signaling
Immunobiology
2020
225
|
| 32329629 |
Cai G et al.:
Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-2
Am. J. Respir. Crit. Care Med.
2020
201: 1557-1559
|
| 19834109 |
Senchenkova EY et al.:
Angiotensin II-mediated microvascular thrombosis
Hypertension
2010
56: 1089-1095
|
| 29491386 |
Missiroli S et al.:
Mitochondria-associated membranes (MAMs) and inflammation
Cell Death Dis
2018
9: 329
|
| 28130445 |
Yu J et al.:
Interferon-inducible LY6E Protein Promotes HIV-1 Infection
J. Biol. Chem.
2017
292: 4674-4685
|
| 30066874 |
Zhou LL et al.:
MicroRNA1433p contributes to the regulation of pain responses in collageninduced arthritis
Mol Med Rep
2018
18: 3219-3228
|
| 25043814 |
Hernandez ED et al.:
A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity
Cell Metab.
2014
20: 499-511
|
| 32442087 |
Belousov DM et al.:
The Dawn of Mitophagy: What Do We Know by Now?
|
| 28694762 |
Rustemoglu A et al.:
Clinical significance of NCOA5 gene rs2903908 polymorphism in Behcets disease
EXCLI J
2017
16: 609-617
|
| 21172874 |
Nemeth K et al.:
The role of osteoclast-associated receptor in osteoimmunology
J. Immunol.
2011
186: 13-18
|
| 31801866 |
Nguyen LP et al.:
PACSIN2 Interacts with Nonstructural Protein 5A and Regulates Hepatitis C Virus Assembly
|
| 28170448 |
Kim SE et al.:
Genome-wide analysis identifies colonic genes differentially associated with serum leptin and insulin concentrations in C57BL/6J mice fed a high-fat diet
PLoS ONE
2017
12
|
| 32366870 |
Pilson Q et al.:
miR-744-5p contributes to ocular inflammation in patients with primary Sjogrens Syndrome
Sci Rep
2020
10: 7484
|
| 26310831 |
Murphy MB et al.:
Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling
J. Leukoc. Biol.
2015
98: 963-974
|
| 25526310 |
Yang S et al.:
The E3 ubiquitin ligase Pellino3 protects against obesity-induced inflammation and insulin resistance
Immunity
2014
41: 973-987
|
| 23892723 |
Yang S et al. et al.:
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
Nat. Immunol.
2013
14: 927-936
|
| 31168659 |
Ganzleben I et al.:
PGAM5 is a key driver of mitochondrial dysfunction in experimental lung fibrosis
Cell. Mol. Life Sci.
2019
76: 4783-4794
|
| 32253918 |
Chen Y et al.:
Phosphoglycerate Mutase 5 Knockdown Alleviates Neuronal Injury After Traumatic Brain Injury Through Drp1-Mediated Mitochondrial Dysfunction
|
| 29423005 |
Ning F et al.:
Transcription factor Phf19 positively regulates germinal center reactions that underlies its role in rheumatoid arthritis
Am J Transl Res
2018
10: 200-211
|
| 27292189 |
Schewe M et al. et al.:
Secreted Phospholipases A2 Are Intestinal Stem Cell Niche Factors with Distinct Roles in Homeostasis, Inflammation, and Cancer
Cell Stem Cell
2016
19: 38-51
|
| 29352288 |
Luo W et al. et al.:
Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication
PLoS Pathog.
2018
14
|
| 28936214 |
Ocon B et al.:
A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15
Front Immunol
2017
8: 1111
|
| 31776454 |
Zhang H et al.:
Correction to: The methyltransferase PRMT6 attenuates antiviral innate immunity by blocking TBK1-IRF3 signaling
Cell. Mol. Immunol.
2020
17: 192
|
| 24875235 |
Sjakste T et al.:
Juvenile idiopathic arthritis subtype- and sex-specific associations with genetic variants in the PSMA6/PSMC6/PSMA3 gene cluster
Pediatr Neonatol
2014
55: 393-403
|
| 25044438 |
Cobat A et al.:
A general efficient and flexible approach for genome-wide association analyses of imputed genotypes in family-based designs
Genet. Epidemiol.
2014
38: 560-571
|
| 22960262 |
Liang Y et al.:
Expression profiling of Rab GTPases reveals the involvement of Rab20 and Rab32 in acute brain inflammation in mice
Neurosci. Lett.
2012
527: 110-114
|
| 17196245 |
Caudy AA et al.:
CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome, and defective IL-10 expression from CD4 lymphocytes
J. Allergy Clin. Immunol.
2007
119: 482-487
|
| 30524198 |
Au DT et al.:
Macrophage LRP1 Promotes Diet-Induced Hepatic Inflammation and Metabolic Dysfunction by Modulating Wnt Signaling
Mediators Inflamm.
2018
2018
|
| 26780215 |
Xing Y et al.:
N-myc downstream-regulated gene 4, up-regulated by tumor necrosis factor-alpha and nuclear factor kappa B, aggravates cardiac ischemia/reperfusion injury by inhibiting reperfusion injury salvage kinase pathway
Basic Res. Cardiol.
2016
111: 11
|
| 30504710 |
Lang F et al.:
Phosphate Homeostasis, Inflammation and the Regulation of FGF-23
Kidney Blood Press. Res.
2018
43: 1742-1748
|
| 20887952 |
Palacios D et al.:
TNF/p38alpha/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration
Cell Stem Cell
2010
7: 455-469
|
| 29884787 |
Delgado-Vega AM et al.:
Whole Exome Sequencing of Patients from Multicase Families with Systemic Lupus Erythematosus Identifies Multiple Rare Variants
Sci Rep
2018
8: 8775
|
| 30179222 |
Braun DA et al. et al.:
Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome
J. Clin. Invest.
2018
128: 4313-4328
|
| 22733747 |
Risco A et al.:
p38gamma and p38delta kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation
Proc Natl Acad Sci U S A
2012
109
|
| 10092105 |
Godar S et al.:
M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-beta1
Eur J Immunol
1999
29: 1004-1013
|
| 17601656 |
Dejkhamron P et al.:
Lipopolysaccharide (LPS) directly suppresses growth hormone receptor (GHR) expression through MyD88-dependent and -independent Toll-like receptor-4/MD2 complex signaling pathways
Mol Cell Endocrinol
2007
274: 35-42
|
| 11859136 |
Feng X et al.:
Cooperation of C1q receptors and integrins in C1q-mediated endothelial cell adhesion and spreading
J Immunol
2002
168: 2441-2448
|
| 32352641 |
Zhang A et al.:
EphA2 phosphorylates NLRP3 and inhibits inflammasomes in airway epithelial cells
EMBO Rep
2020
21
|
| 20923762 |
You R et al.:
The first type III repeat in fibronectin activates an inflammatory pathway in dermal fibroblasts
J Biol Chem
2010
285
|
| 25907862 |
Lindner M et al. et al.:
Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9
Brain
2015
138: 1875-1893
|
| 30117676 |
Liso A et al.:
From fever to immunity: A new role for IGFBP-6?
J Cell Mol Med
2018
22: 4588-4596
|
| 20693423 |
Tadagavadi RK et al.:
Netrin-1 regulates Th1/Th2/Th17 cytokine production and inflammation through UNC5B receptor and protects kidney against ischemia-reperfusion injury
J Immunol
2010
185: 3750-3758
|
| 11145590 |
Kang HC et al.:
Pax-8 is essential for regulation of the thyroglobulin gene by transforming growth factor-beta1
Endocrinology
2001
142: 267-275
|
| 24459235 |
Kulkarni OP et al.:
Toll-like receptor 4-induced IL-22 accelerates kidney regeneration
J Am Soc Nephrol
2014
25: 978-989
|
| 12370360 |
Liao YC et al.:
IL-19 induces production of IL-6 and TNF-alpha and results in cell apoptosis through TNF-alpha
J Immunol
2002
169: 4288-4297
|
| 10585776 |
Hu S et al.:
Characterization of TNFRSF19, a novel member of the tumor necrosis factor receptor superfamily
Genomics
1999
62: 103-107
|
| 30104686 |
Wang J et al.:
TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-kappaB pathway
Sci Rep
2018
8: 12079
|
| 15936721 |
Hu Y et al.:
A novel inflammation-induced ubiquitin E3 ligase in alveolar type II cells
Biochem Biophys Res Commun
2005
333: 253-263
|
| 21865167 |
Scott AJ et al.:
Reactive oxygen species and p38 mitogen-activated protein kinase mediate tumor necrosis factor alpha-converting enzyme (TACE/ADAM-17) activation in primary human monocytes
J Biol Chem
2011
286
|
| 20028977 |
Ohashi K et al.:
Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype
J Biol Chem
2010
285: 6153-6160
|
| 31676329 |
Jin H et al. et al.:
Innate Immune Signaling Contributes to Tubular Cell Senescence in the Glis2 Knockout Mouse Model of Nephronophthisis
Am J Pathol
2020
190: 176-189
|
| 31589169 |
Kishi S et al. et al.:
Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses
J Clin Invest
2019
129: 4797-4816
|
| 33936007 |
Xia W et al.:
Congenital Human Cytomegalovirus Infection Inducing Sensorineural Hearing Loss
Front Microbiol
2021
12
|
| 19909294 |
Petrosino S et al. et al.:
Protective role of palmitoylethanolamide in contact allergic dermatitis
Allergy
2010
65: 698-711
|
| 21377743 |
Song JJ et al.:
Microarray analysis of microRNA expression in LPS induced inflammation of human middle ear epithelial cells (HMEECs)
Int J Pediatr Otorhinolaryngol
2011
75: 648-651
|
| 27976413 |
Aghazadeh Tabrizi M et al.:
Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists
Med Res Rev
2017
37: 936-983
|
| 31921123 |
Sindura KP et al.:
An Immunological Perspective to Non-syndromic Sensorineural Hearing Loss
Front Immunol
2019
10: 2848
|
| 33625944 |
Shi X et al. et al.:
Reticulocalbin 3 deficiency in alveolar epithelium attenuated LPS-induced ALI via NF-kappaB signaling
Am J Physiol Lung Cell Mol Physiol
2021
320: L627-L639
|
| 32636717 |
author information missing
article information missing
|
| 26161641 |
author information missing
article information missing
|
| 29276512 |
author information missing
article information missing
|
| 34224773 |
author information missing
article information missing
|
| 8106393 |
author information missing
article information missing
|
| 34021047 |
author information missing
article information missing
|
| 33874983 |
author information missing
article information missing
|
| 33811647 |
author information missing
article information missing
|
| 21277567 |
author information missing
article information missing
|
| 12738410 |
author information missing
article information missing
|
| 23468852 |
author information missing
article information missing
|
| 33532035 |
author information missing
article information missing
|
| 17142562 |
author information missing
article information missing
|
| 28685269 |
author information missing
article information missing
|
| 26404542 |
author information missing
article information missing
|
| 23728300 |
author information missing
article information missing
|
| 30089837 |
author information missing
article information missing
|
| 35319239 |
author information missing
article information missing
|
| 16521186 |
author information missing
article information missing
|
| 26808524 |
author information missing
article information missing
|
| 18439548 |
author information missing
article information missing
|
| 23374270 |
Stepensky P et al.:
Deficiency of caspase recruitment domain family, member 11 (CARD11), causes profound combined immunodeficiency in human subjects
J. Allergy Clin. Immunol.
2013
131: 477-485
|
| 23727036 |
Jabara HH et al.:
A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency
J. Allergy Clin. Immunol.
2013
132: 151-158
|
| 23365458 |
Mace EM et al.:
Mutations in GATA2 cause human NK cell deficiency with specific loss of the CD56(bright) subset
Blood
2013
121: 2669-2677
|
| 26981933 |
Kuehn HS et al.:
Loss of B Cells in Patients with Heterozygous Mutations in IKAROS
N. Engl. J. Med.
2016
374: 1032-1043
|
| 24136356 |
Angulo I et al.:
Phosphoinositide 3-kinase delta gene mutation predisposes to respiratory infection and airway damage
Science
2013
342: 866-871
|
| 23579497 |
Bolze A et al.:
Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia
Science
2013
340: 976-978
|
| 25512081 |
Alkhairy OK et al.:
RAC2 loss-of-function mutation in 2 siblings with characteristics of common variable immunodeficiency
J. Allergy Clin. Immunol.
2015
135: 1380-1384
|
| 10758162 |
Ambruso DR et al.:
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
Proc. Natl. Acad. Sci. U.S.A.
2000
97: 4654-4659
|
| 28530713 |
Afzali B et al. et al.:
BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency
Nat. Immunol.
2017
18: 813-823
|
| 12626442 |
Jaatinen T et al.:
Total C4B deficiency due to gene deletion and gene conversion in a patient with severe infections
Clin. Diagn. Lab. Immunol.
2003
10: 195-201
|
| 26365386 |
Frugoni F et al. et al.:
A novel mutation in the POLE2 gene causing combined immunodeficiency
J. Allergy Clin. Immunol.
2016
137: 635-638.e1
|
| 32436864 |
Pothlichet J et al. et al.:
PLA2G1B is involved in CD4 anergy and CD4 lymphopenia in HIV-infected patients
J Clin Invest
2020
130: 2872-2887
|
| 17676033 |
author information missing
article information missing
|
| 24921217 |
Lam AP et al.:
Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis
Am. J. Respir. Crit. Care Med.
2014
190: 185-195
|
| 24429156 |
Noth I et al.:
Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study
Lancet Respir Med
2013
1: 309-317
|
| 21642472 |
Zhou Q et al.:
Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis
FASEB J.
2011
25: 3032-3044
|
| 24424167 |
Kekevian A et al.:
Diagnosis and classification of idiopathic pulmonary fibrosis
Autoimmun Rev
2014
13: 508-512
|
| 20656946 |
van Moorsel CH et al.:
Surfactant protein C mutations are the basis of a significant portion of adult familial pulmonary fibrosis in a dutch cohort
Am. J. Respir. Crit. Care Med.
2010
182: 1419-1425
|
| 19100526 |
Wang Y et al.:
Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer
Am. J. Hum. Genet.
2009
84: 52-59
|
| 17392301 |
Armanios MY et al.:
Telomerase mutations in families with idiopathic pulmonary fibrosis
N. Engl. J. Med.
2007
356: 1317-1326
|
| 24504062 |
author information missing
A novel dyskerin (DKC1) mutation is associated with familial interstitial pneumonia
Chest
2014
146: E1-E7
|
| 25539146 |
author information missing
Exome Sequencing Identifies Mutant TINF2 in a Family With Pulmonary Fibrosis
Chest
2015
147: 1361-1368
|
| 19255294 |
Kinder BW et al.:
Serum surfactant protein-A is a strong predictor of early mortality in idiopathic pulmonary fibrosis
Chest
2009
135: 1557-1563
|
| 25607374 |
Cogan JD et al.:
Rare variants in RTEL1 are associated with familial interstitial pneumonia
Am. J. Respir. Crit. Care Med.
2015
191: 646-655
|
| 24072216 |
Fukuhara A et al.:
Pulmonary fibrosis in dyskeratosis congenita with TINF2 gene mutation
Eur. Respir. J.
2013
42: 1757-1759
|
| 23583980 |
Fingerlin TE et al.:
Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
Nat. Genet.
2013
45: 613-620
|
| 21757622 |
Alder JK et al.:
Telomere length is a determinant of emphysema susceptibility
Am. J. Respir. Crit. Care Med.
2011
184: 904-912
|
| 23268535 |
Kropski JA et al.:
Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis
Dis Model Mech
2013
6: 9-17
|
| 15778495 |
Mulugeta S et al.:
A surfactant protein C precursor protein BRICHOS domain mutation causes endoplasmic reticulum stress, proteasome dysfunction, and caspase 3 activation
Am. J. Respir. Cell Mol. Biol.
2005
32: 521-530
|
| 18390830 |
Lawson WE et al.:
Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection
Am. J. Physiol. Lung Cell Mol. Physiol.
2008
294
|
| 18635891 |
Korfei M et al.:
Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis
Am. J. Respir. Crit. Care Med.
2008
178: 838-846
|
| 20466729 |
Maitra M et al.:
Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress
J. Biol. Chem.
2010
285
|
| 12791891 |
Tang YW et al.:
Herpesvirus DNA is consistently detected in lungs of patients with idiopathic pulmonary fibrosis
J. Clin. Microbiol.
2003
41: 2633-2640
|
| 21498628 |
Marmai C et al.:
Alveolar epithelial cells express mesenchymal proteins in patients with idiopathic pulmonary fibrosis
Am. J. Physiol. Lung Cell Mol. Physiol.
2011
301: L71-L78
|
| 21757695 |
Tanjore H et al.:
Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress
J. Biol. Chem.
2011
286
|
| 21224216 |
Minagawa S et al.:
Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-beta-induced senescence of human bronchial epithelial cells
Am. J. Physiol. Lung Cell Mol. Physiol.
2011
300: L391-L401
|
| 12707032 |
Chilosi M et al.:
Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis
Am. J. Pathol.
2003
162: 1495-1502
|
| 22241478 |
Zhou B et al.:
Interactions between beta-catenin and transforming growth factor-beta signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP)
J. Biol. Chem.
2012
287: 7026-7038
|
| 19287097 |
Konigshoff M et al.:
WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis
J. Clin. Invest.
2009
119: 772-787
|
| 21212602 |
Kim TH et al.:
Blockade of the Wnt/beta-catenin pathway attenuates bleomycin-induced pulmonary fibrosis
Tohoku J. Exp. Med.
2011
223: 45-54
|
| 26207697 |
Semren N et al.:
Regulation of 26S Proteasome Activity in Pulmonary Fibrosis
|
| 26186945 |
Im J et al.:
Reduced FoxO3a expression causes low autophagy in Idiopathic Pulmonary Fibrosis fibroblasts on collagen matrix
|
| 25199049 |
Francois D et al.:
Increased expression of protease nexin-1 in fibroblasts during idiopathic pulmonary fibrosis regulates thrombin activity and fibronectin expression
Lab. Invest.
2014
94: 1237-1246
|
| 19701206 |
Hecker L et al.:
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
Nat. Med.
2009
15: 1077-1081
|
| 24718857 |
Hecker L et al.:
Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance
Sci Transl Med
2014
6: 231ra47
|
| 20643828 |
Liu G et al.:
miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
J. Exp. Med.
2010
207: 1589-1597
|
| 23822889 |
Li P et al.:
Serum miR-21 and miR-155 expression in idiopathic pulmonary fibrosis
J Asthma
2013
50: 960-964
|
| 25612003 |
Khalil W et al.:
Pathologic Regulation of Collagen I by an Aberrant PP2A/HDAC4/miR-29 Signal Axis in IPF Fibroblasts
|
| 22364217 |
Tsang AR et al.:
hTERT mutations associated with idiopathic pulmonary fibrosis affect telomerase activity, telomere length, and cell growth by distinct mechanisms
Aging Cell
2012
11: 482-490
|
| 23516479 |
Le Saux CJ et al.:
A novel telomerase activator suppresses lung damage in a murine model of idiopathic pulmonary fibrosis
PLoS ONE
2013
8
|
| 20395557 |
Pandit KV et al.:
Inhibition and role of let-7d in idiopathic pulmonary fibrosis
Am. J. Respir. Crit. Care Med.
2010
182: 220-229
|
| 26415510 |
Andre PA et al.:
BARD1 mediates TGF-beta signaling in pulmonary fibrosis
Respir. Res.
2015
16: 118
|
| 24953558 |
Berschneider B et al.:
miR-92a regulates TGF-beta1-induced WISP1 expression in pulmonary fibrosis
Int. J. Biochem. Cell Biol.
2014
53: 432-441
|
| 26538547 |
Newman DR et al.:
Expression of WNT5A in Idiopathic Pulmonary Fibrosis and its Control by TGF-beta and WNT7B in Human Lung Fibroblasts
|
| 31387171 |
Shao M et al. et al.:
Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-beta1 in alveolar epithelial cells
Biomed. Pharmacother.
2019
117
|
| 18441099 |
Li X et al.:
Angiotensin converting enzyme-2 is protective but downregulated in human and experimental lung fibrosis
Am. J. Physiol. Lung Cell Mol. Physiol.
2008
295: L178-L185
|
| 32664949 |
Xu J et al.:
SARS-CoV-2 induces transcriptional signatures in human lung epithelial cells that promote lung fibrosis
Respir Res
2020
21: 182
|
| 18192592 |
author information missing
Increased pulmonary vascular resistance and defective pulmonary artery filling in caveolin-1-/- mice
Am. J. Physiol. Lung Cell Mol. Physiol.
2008
294: L865-L873
|
| 24951767 |
Austin ED et al.:
The genetics of pulmonary arterial hypertension
Circ. Res.
2014
115: 189-202
|
| 19211612 |
Shintani M et al.:
A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension
J. Med. Genet.
2009
46: 331-337
|
| 25411245 |
Prewitt AR et al.:
Heterozygous null bone morphogenetic protein receptor type 2 mutations promote SRC kinase-dependent caveolar trafficking defects and endothelial dysfunction in pulmonary arterial hypertension
J. Biol. Chem.
2015
290: 960-971
|
| 18024717 |
Frank DB et al.:
Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature
Am. J. Physiol. Lung Cell Mol. Physiol.
2008
294: L98-L109
|
| 1603138 |
Christman BW et al.:
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension
N. Engl. J. Med.
1992
327: 70-75
|
| 7735624 |
Humbert M et al.:
Increased interleukin-1 and interleukin-6 serum concentrations in severe primary pulmonary hypertension
Am. J. Respir. Crit. Care Med.
1995
151: 1628-1631
|
| 16548900 |
Itoh T et al.:
Increased plasma monocyte chemoattractant protein-1 level in idiopathic pulmonary arterial hypertension
Respirology
2006
11: 158-163
|
| 24124488 |
Price LC et al.:
Nuclear factor kappa-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension
PLoS ONE
2013
8
|
| 25621163 |
Neary MT et al.:
Myosin heavy chain 15 is associated with bovine pulmonary arterial pressure
Pulm Circ
2014
4: 496-503
|
| 27486806 |
Bujak R et al.:
New Biochemical Insights into the Mechanisms of Pulmonary Arterial Hypertension in Humans
PLoS ONE
2016
11
|
| 30274504 |
Lee H et al.:
Change of voltage-gated potassium channel 1.7 expressions in monocrotaline-induced pulmonary arterial hypertension rat model
Korean J Pediatr
2018
61: 271-278
|
| 25857284 |
Dau T et al.:
Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors
Nat Commun
2015
6: 6722
|
| 24292273 |
Eyries M et al.:
EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension
Nat. Genet.
2014
46: 65-69
|
| 25512148 |
Tenorio J et al.:
A founder EIF2AK4 mutation causes an aggressive form of pulmonary arterial hypertension in Iberian Gypsies
|
| 22593209 |
Uringa EJ et al.:
RTEL1 contributes to DNA replication and repair and telomere maintenance
Mol. Biol. Cell
2012
23: 2782-2792
|
| 15928077 |
Masutomi K et al.:
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses
Proc. Natl. Acad. Sci. U.S.A.
2005
102: 8222-8227
|
| 23927510 |
Theall KP et al.:
Early hits and long-term consequences: tracking the lasting impact of prenatal smoke exposure on telomere length in children
Am J Public Health
2013
103: S133-S135
|
| 18952756 |
Lee J et al.:
Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice
Am. J. Physiol. Lung Cell Mol. Physiol.
2009
296: L57-L70
|
| 11076809 |
Driscoll B et al.:
Telomerase in alveolar epithelial development and repair
Am. J. Physiol. Lung Cell Mol. Physiol.
2000
279
|
| 22723415 |
Hoffmeyer K et al.:
Wnt/beta-catenin signaling regulates telomerase in stem cells and cancer cells
Science
2012
336: 1549-1554
|
| 21435439 |
Hu B et al.:
Essential role of MeCP2 in the regulation of myofibroblast differentiation during pulmonary fibrosis
Am. J. Pathol.
2011
178: 1500-1508
|
| 24317696 |
Roy MG et al.:
Muc5b is required for airway defence
Nature
2014
505: 412-416
|
| 11718719 |
Yamano G et al.:
ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells
FEBS Lett.
2001
508: 221-225
|
| 9606191 |
Dennler S et al.:
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
EMBO J.
1998
17: 3091-3100
|
| 11790560 |
Baer R et al.:
The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity
Curr. Opin. Genet. Dev.
2002
12: 86-91
|
| 19176389 |
Ryser S et al.:
Distinct roles of BARD1 isoforms in mitosis: full-length BARD1 mediates Aurora B degradation, cancer-associated BARD1beta scaffolds Aurora B and BRCA2
Cancer Res.
2009
69: 1125-1134
|
| 23542012 |
Albayrak A et al.:
Protective effects of lithium: a new look at an old drug with potential antioxidative and anti-inflammatory effects in an animal model of sepsis
Int. Immunopharmacol.
2013
16: 35-40
|
| 30761137 |
Vieira RS et al.:
Butyrate Attenuates Lung Inflammation by Negatively Modulating Th9 Cells
Front Immunol
2019
10: 67
|
| 30058099 |
Liu Q et al.:
2,3-Butanediol catabolism in Pseudomonas aeruginosa PAO1
Environ. Microbiol.
2018
20: 3927-3940
|
| 27177192 |
Nguyen M et al.:
The fermentation product 2,3-butanediol alters P. aeruginosa clearance, cytokine response and the lung microbiome
ISME J
2016
10: 2978-2983
|
| 28521775 |
Manichaikul A et al. et al.:
Genome-wide association study of subclinical interstitial lung disease in MESA
Respir. Res.
2017
18: 97
|
| 27377409 |
Christmann RB et al. et al.:
miR-155 in the progression of lung fibrosis in systemic sclerosis
Arthritis Res. Ther.
2016
18: 155
|
| 31562139 |
Nakajima K et al. et al.:
Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice
|
| 20576117 |
Niese KA et al.:
The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis
Respir. Res.
2010
11: 87
|
| 20848133 |
Buckley ST et al.:
Differential susceptibility to epithelial-mesenchymal transition (EMT) of alveolar, bronchial and intestinal epithelial cells in vitro and the effect of angiotensin II receptor inhibition
Cell Tissue Res.
2010
342: 39-51
|
| 16620134 |
Ribeiro CM et al.:
The role of intracellular calcium signals in inflammatory responses of polarised cystic fibrosis human airway epithelia
Drugs R D
2006
7: 17-31
|
| 30918468 |
de Carvalho Santuchi M et al. et al.:
Angiotensin-(1-7) and Alamandine Promote Anti-inflammatory Response in Macrophages In Vitro and In Vivo
Mediators Inflamm.
2019
2019
|
| 22009550 |
Wosten-van Asperen RM et al.:
Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist
J. Pathol.
2011
225: 618-627
|
| 23613465 |
Triantafilou K et al.:
The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation
J. Cell. Sci.
2013
126: 2903-2913
|
| 28935640 |
Sodhi CP et al.:
Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg(9) bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration
Am. J. Physiol. Lung Cell Mol. Physiol.
2018
314: L17-L31
|
| 20581171 |
Shenoy V et al. et al.:
The angiotensin-converting enzyme 2/angiogenesis-(1-7)/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertension
Am. J. Respir. Crit. Care Med.
2010
182: 1065-1072
|
| 12754187 |
Marshall RP et al.:
Angiotensin II and the fibroproliferative response to acute lung injury
Am. J. Physiol. Lung Cell Mol. Physiol.
2004
286: L156-L164
|
| 28944831 |
Xu J et al.:
Vitamin D alleviates lipopolysaccharideinduced acute lung injury via regulation of the reninangiotensin system
Mol Med Rep
2017
16: 7432-7438
|
| 24626731 |
Ikejiri AT et al.:
Gene expression profile of oxidative stress in the lung of inbred mice after intestinal ischemia/reperfusion injury
Acta Cir Bras
2014
29: 186-192
|
| 17008636 |
LeSimple P et al.:
Trefoil factor family 3 peptide promotes human airway epithelial ciliated cell differentiation
Am J Respir Cell Mol Biol
2007
36: 296-303
|
| 25904058 |
Londhe VA et al.:
Overexpression of LINCR in the developing mouse lung epithelium inhibits distal differentiation and induces cystic changes
Dev Dyn
2015
244: 827-838
|
| 22003095 |
Vohra PK et al.:
Dopamine inhibits pulmonary edema through the VEGF-VEGFR2 axis in a murine model of acute lung injury
Am J Physiol Lung Cell Mol Physiol
2012
302: L185-L192
|
| 19383981 |
author information missing
article information missing
|
| 35580897 |
author information missing
article information missing
|
| 21552194 |
Maes M et al.:
Lower whole blood glutathione peroxidase (GPX) activity in depression, but not in myalgic encephalomyelitis / chronic fatigue syndrome: another pathway that may be associated with coronary artery disease and neuroprogression in depression
Neuro Endocrinol. Lett.
2011
32: 133-140
|
| 21256177 |
Erdem M et al.:
Serum haptoglobin levels in patients with melancholic and nonmelancholic major depression
Prog. Neuropsychopharmacol. Biol. Psychiatry
2011
35: 944-947
|
| 20951793 |
Janelidze S et al.:
Cytokine levels in the blood may distinguish suicide attempters from depressed patients.
Brain Behav. Immun.
2011
25: 335-339
|
| 19129380 |
Song C et al.:
Increased phospholipase A2 activity and inflammatory response but decreased nerve growth factor expression in the olfactory bulbectomized rat model of depression: effects of chronic ethyl-eicosapentaenoate treatment
J. Neurosci.
2009
29: 14-22
|
| 20479761 |
Shelton RC et al.:
Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression.
Mol. Psychiatry
2011
16: 751-762
|
| 20161799 |
Domenici E et al. et al.:
Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections
PLoS ONE
2010
5: e9166
|
| 21605657 |
Sublette ME et al.:
Plasma kynurenine levels are elevated in suicide attempters with major depressive disorder
Brain Behav. Immun.
2011
25: 1272-1278
|
| 21466824 |
Bay-Richter C et al.:
Changes in behaviour and cytokine expression upon a peripheral immune challenge.
Behav. Brain Res.
2011
222: 193-199
|
| 21312291 |
Yoshimura R et al.:
Plasma levels of brain-derived neurotrophic factor and interleukin-6 in patients with dysthymic disorder: comparison with age- and sex-matched major depressed patients and healthy controls.
Hum Psychopharmacol
2010
25: 566-569
|
| 21756997 |
Hafner S et al.:
Association between social isolation and inflammatory markers in depressed and non-depressed individuals: results from the MONICA/KORA study
Brain Behav. Immun.
2011
25: 1701-1707
|
| 21521612 |
Kohli MA et al.:
The neuronal transporter gene SLC6A15 confers risk to major depression.
Neuron
2011
70: 252-265
|
| 11343523 |
Reichenberg A et al.:
Cytokine-associated emotional and cognitive disturbances in humans
Arch. Gen. Psychiatry
2001
58: 445-452
|
| 21448457 |
Wolkowitz OM et al.:
Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings.
PLoS ONE
2011
6
|
| 21421043 |
Weigelt K et al.:
TREM-1 and DAP12 expression in monocytes of patients with severe psychiatric disorders. EGR3, ATF3 and PU.1 as important transcription factors.
Brain Behav. Immun.
2011
25: 1162-1169
|
| 11323674 |
Bouchon A et al.:
TREM-1 amplifies inflammation and is a crucial mediator of septic shock.
Nature
2001
410: 1103-1107
|
| 20176930 |
Cole SW et al.:
Computational identification of gene-social environment interaction at the human IL6 locus
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 5681-5686
|
| 19073750 |
Miller GE et al.:
Chronic interpersonal stress predicts activation of pro- and anti-inflammatory signaling pathways 6 months later
Psychosom Med
2009
71: 57-62
|
| 8891088 |
Seidel A et al.:
Major depressive disorder is associated with elevated monocyte counts.
Acta Psychiatr Scand
1996
94: 198-204
|
| 1488478 |
Dunbar PR et al.:
Neopterin measurement provides evidence of altered cell-mediated immunity in patients with depression, but not with schizophrenia.
Psychol Med
1992
22: 1051-1057
|
| 7511248 |
Maes M et al.:
Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression
Psychiatry Res
1993
49: 11-27
|
| 10232390 |
Mendlovic S et al.:
Immune activation in non-treated suicidal major depression.
Immunol. Lett.
1999
67: 105-108
|
| 21630437 |
Schosser A et al.:
A follow-up case-control association study of tractable (druggable) genes in recurrent major depression
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2011
156B: 640-650
|
| 20237460 |
Unschuld PG et al.:
Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response
Neuropsychopharmacology
2010
35: 1583-1592
|
| 20124106 |
Kohli MA et al.:
Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients
Arch. Gen. Psychiatry
2010
67: 348-359
|
| 20673876 |
Rietschel M et al.:
Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression
Biol. Psychiatry
2010
68: 578-585
|
| 19125159 |
Kloiber S et al.:
Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression
Mol. Psychiatry
2010
15: 736-747
|
| 15565110 |
Binder EB et al.:
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment.
Nat. Genet.
2004
36: 1319-1325
|
| 21631159 |
Horstmann S et al.:
Glucocorticoids as predictors of treatment response in depression
Harv Rev Psychiatry
2011
19: 125-143
|
| 21347384 |
Scharf SH et al.:
Expression and regulation of the Fkbp5 gene in the adult mouse brain
PLoS ONE
2011
6
|
| 20658274 |
Muller N et al.:
Inflammatory biomarkers and depression
Neurotox Res
2011
19: 308-318
|
| 20130443 |
Matthes S et al.:
Tryptophan hydroxylase as novel target for the treatment of depressive disorders
Pharmacology
2010
85: 95-109
|
| 21521612 |
Kohli MA et al.:
The neuronal transporter gene SLC6A15 confers risk to major depression
Neuron
2011
70: 252-265
|
| 17098775 |
Roider HG et al.:
Predicting transcription factor affinities to DNA from a biophysical model.
Bioinformatics
2007
23: 134-141
|
| 22525660 |
Carlini VP et al.:
Acute ghrelin administration reverses depressive-like behavior induced by bilateral olfactory bulbectomy in mice
Peptides
2012
35: 160-165
|
| 20888580 |
Kluge M et al.:
Effects of ghrelin on psychopathology, sleep and secretion of cortisol and growth hormone in patients with major depression
J Psychiatr Res
2011
45: 421-426
|
| 16453251 |
Murck H et al.:
Renin-angiotensin-aldosterone system, HPA-axis and sleep-EEG changes in unmedicated patients with depression after total sleep deprivation
Pharmacopsychiatry
2006
39: 23-29
|
| 19521111 |
Kluge M et al.:
Ghrelin plasma levels are not altered in major depression
Neuropsychobiology
2009
59: 199-204
|
| 18533184 |
Murck H et al.:
The glutamatergic system and its relation to the clinical effect of therapeutic-sleep deprivation in depression - an MR spectroscopy study
J Psychiatr Res
2009
43: 175-180
|
| 17337164 |
Kluge M et al.:
Duloxetine increases stage 3 sleep and suppresses rapid eye movement (REM) sleep in patients with major depression
Eur Neuropsychopharmacol
2007
17: 527-531
|
| 16237393 |
Schmid DA et al.:
Changes of sleep architecture, spectral composition of sleep EEG, the nocturnal secretion of cortisol, ACTH, GH, prolactin, melatonin, ghrelin, and leptin, and the DEX-CRH test in depressed patients during treatment with mirtazapine
Neuropsychopharmacology
2006
31: 832-844
|
| 16112814 |
Held K et al.:
Neuropeptide Y (NPY) shortens sleep latency but does not suppress ACTH and cortisol in depressed patients and normal controls
Psychoneuroendocrinology
2006
31: 100-107
|
| 22832852 |
Martins-de-Souza D et al.:
Identification of proteomic signatures associated with depression and psychotic depression in post-mortem brains from major depression patients
Transl Psychiatry
2012
2: E87
|
| 20048074 |
Thoms HC et al.:
Nucleolar targeting of RelA(p65) is regulated by COMMD1-dependent ubiquitination
Cancer Res.
2010
70: 139-149
|
| 16751101 |
Lin X et al.:
PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling
Cell
2006
125: 915-928
|
| 7706261 |
Schmitz ML et al.:
Interaction of the COOH-terminal transactivation domain of p65 NF-kappa B with TATA-binding protein, transcription factor IIB, and coactivators
J. Biol. Chem.
1995
270: 7219-7226
|
| 15553237 |
Kato Y et al.:
Screening of the interaction between xenobiotic transporters and PDZ proteins
Pharm. Res.
2004
21: 1886-1894
|
| 11751930 |
Yun CC et al.:
Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2
J. Biol. Chem.
2002
277: 7676-7683
|
| 17353931 |
Ewing RM et al.:
Large-scale mapping of human protein-protein interactions by mass spectrometry
Mol. Syst. Biol.
2007
3: 89
|
| 9122164 |
Pause A et al.:
The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins
Proc. Natl. Acad. Sci. U.S.A.
1997
94: 2156-2161
|
| 17183367 |
Maine GN et al.:
COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase
EMBO J.
2007
26: 436-447
|
| 18644199 |
Ueda K et al.:
Effect of oil-in-water lipid emulsions prepared with fish oil or soybean oil on the growth of MCF-7 cells and HepG2 cells
J. Pharm. Pharmacol.
2008
60: 1069-1075
|
| 19734906 |
Chang M et al.:
Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production
Nat. Immunol.
2009
10: 1089-1095
|
| 9878049 |
Pfeiffer R et al.:
Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family
EMBO J.
1999
18: 49-57
|
| 15280038 |
Rotoli BM et al.:
INFgamma stimulates arginine transport through system y+L in human monocytes
FEBS Lett.
2004
571: 177-181
|
| 20970119 |
Malki K et al.:
Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants
Biol. Psychiatry
2011
69: 360-365
|
| 19220812 |
Muller PA et al.:
Nuclear-cytosolic transport of COMMD1 regulates NF-kappaB and HIF-1 activity
Traffic
2009
10: 514-527
|
| 10559880 |
Kotlyarov A et al.:
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis
Nat. Cell Biol.
1999
1: 94-97
|
| 18930133 |
Sun W et al.:
PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation
Cell. Signal.
2009
21: 95-102
|
| 19953087 |
Persaud A et al.:
Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays
Mol. Syst. Biol.
2009
5: 333
|
| 26050039 |
Arloth J et al.:
Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders
Neuron
2015
86: 1189-1202
|
| 21665277 |
Yang IV et al.:
Identification of novel innate immune genes by transcriptional profiling of macrophages stimulated with TLR ligands
Mol. Immunol.
2011
48: 1886-1895
|
| 16212511 |
Feng XH et al.:
Specificity and versatility in tgf-beta signaling through Smads
Annu. Rev. Cell Dev. Biol.
2005
21: 659-693
|
| 10644691 |
Strovel ET et al.:
Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription
J. Biol. Chem.
2000
275: 2399-2403
|
| 16890162 |
Xiong B et al.:
Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity
Dev. Cell
2006
11: 225-238
|
| 12151396 |
Maekawa M et al.:
Identification of the Anti-proliferative protein Tob as a MAPK substrate
J. Biol. Chem.
2002
277
|
| 19560279 |
Binder EB et al.:
The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders
Psychoneuroendocrinology
2009
34: S186-S195
|
| 12519866 |
Vermeer H et al.:
Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression: a potential marker for glucocorticoid sensitivity, potency, and bioavailability
J. Clin. Endocrinol. Metab.
2003
88: 277-284
|
| 20724638 |
Li N et al.:
mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists
Science
2010
329: 959-964
|
| 12438547 |
Takebayashi M et al.:
Nerve growth factor-induced neurite sprouting in PC12 cells involves sigma-1 receptors: implications for antidepressants
J. Pharmacol. Exp. Ther.
2002
303: 1227-1237
|
| 21900206 |
Vinayagam A et al.:
A directed protein interaction network for investigating intracellular signal transduction
Sci Signal
2011
4: RS8
|
| 10930578 |
Ingley E et al.:
PKB/Akt interacts with inosine-5 monophosphate dehydrogenase through its pleckstrin homology domain
FEBS Lett.
2000
478: 253-259
|
| 21199218 |
Yu T et al.:
Regulation of trafficking of activated TrkA is critical for NGF-mediated functions
Traffic
2011
12: 521-534
|
| 12213593 |
Vermeulen L et al.:
Regulation of the transcriptional activity of the nuclear factor-kappaB p65 subunit
Biochem. Pharmacol.
2002
64: 963-970
|
| 22634067 |
Liu R et al.:
Citalopram alleviates chronic stress induced depression-like behaviors in rats by activating GSK3beta signaling in dorsal hippocampus
Brain Res.
2012
1467: 10-17
|
| 22472057 |
Chen YC et al.:
The effect of citalopram on chronic stress-induced depressive-like behavior in rats through GSK3beta/beta-catenin activation in the medial prefrontal cortex
Brain Res. Bull.
2012
88: 338-344
|
| 22205190 |
Murrough JW et al.:
Ketamine as a novel antidepressant: from synapse to behavior
Clin. Pharmacol. Ther.
2012
91: 303-309
|
| 23021380 |
Peyrot WJ et al.:
Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample
J Affect Disord
2013
146: 91-99
|
| 20520284 |
Lee SH et al.:
MRP1 polymorphisms associated with citalopram response in patients with major depression
J Clin Psychopharmacol
2010
30: 116-125
|
| 21341745 |
Broccatelli F et al.:
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields
J. Med. Chem.
2011
54: 1740-1751
|
| 12067980 |
Comerford KM et al.:
Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene
Cancer Res.
2002
62: 3387-3394
|
| 12084725 |
Ambrosini G et al.:
Transcriptional activation of the human leptin gene in response to hypoxia. Involvement of hypoxia-inducible factor 1
J. Biol. Chem.
2002
277
|
| 8968657 |
Baumann P et al.:
Pharmacokinetic-pharmacodynamic relationship of the selective serotonin reuptake inhibitors
Clin Pharmacokinet
1996
31: 444-469
|
| 1498856 |
van Kammen DP et al.:
CSF noradrenergic activity and sleep EEG in clinically stable schizophrenic patients after haloperidol withdrawal
Clin Neuropharmacol
1992
15: 325A-326A
|
| 14612449 |
Roth U et al.:
The transcription factors HIF-1 and HNF-4 and the coactivator p300 are involved in insulin-regulated glucokinase gene expression via the phosphatidylinositol 3-kinase/protein kinase B pathway
J. Biol. Chem.
2004
279: 2623-2631
|
| 16134944 |
Elsner J et al.:
Pharmacophore-guided drug discovery investigations leading to bioactive 5-aminotetrahydropyrazolopyridines. Implications for the binding mode of heterocyclic dopamine D3 receptor agonists
J. Med. Chem.
2005
48: 5771-5779
|
| 9412467 |
Liu G et al.:
Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway
J. Cell Biol.
1997
139: 1719-1733
|
| 22408745 |
Guo M et al.:
Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression
Transl Psychiatry
2012
2: E83
|
| 12734206 |
He HJ et al.:
Interaction of filamin A with the insulin receptor alters insulin-dependent activation of the mitogen-activated protein kinase pathway
J. Biol. Chem.
2003
278
|
| 16335904 |
Buhl ES et al.:
Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats
Am. J. Physiol. Endocrinol. Metab.
2010
298: E920-E929
|
| 7664822 |
Mierau J et al.:
Pramipexole binding and activation of cloned and expressed dopamine D2, D3 and D4 receptors
Eur. J. Pharmacol.
1995
290: 29-36
|
| 11543737 |
Owens MJ et al.:
Second-generation SSRIs: human monoamine transporter binding profile of escitalopram and R-fluoxetine
Biol. Psychiatry
2001
50: 345-350
|
| 17916059 |
Bareggi SR et al.:
The use of escitalopram beyond major depression: pharmacological aspects, efficacy and tolerability in anxiety disorders
Expert Opin Drug Metab Toxicol
2007
3: 741-753
|
| 23468908 |
Wang Y et al.:
A neuropeptide Y variant (rs16139) associated with major depressive disorder in replicate samples from Chinese Han population
PLoS ONE
2013
8
|
| 23567366 |
Michikawa T et al.:
Higher serum dehydroepiandrosterone sulfate levels are protectively associated with depressive symptoms in men, but not in women: a community-based cohort study of older Japanese
Am J Geriatr Psychiatry
2013
21: 1154-1163
|
| 20038947 |
Shyn SI et al.:
Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies
Mol. Psychiatry
2011
16: 202-215
|
| 23690912 |
Corena-McLeod M et al.:
New model of action for mood stabilizers: phosphoproteome from rat pre-frontal cortex synaptoneurosomal preparations
PLoS ONE
2013
8
|
| 22836882 |
Lisowski P et al.:
Effects of chronic stress on prefrontal cortex transcriptome in mice displaying different genetic backgrounds
J. Mol. Neurosci.
2013
50: 33-57
|
| 18536703 |
Surget A et al.:
Corticolimbic transcriptome changes are state-dependent and region-specific in a rodent model of depression and of antidepressant reversal
Neuropsychopharmacology
2009
34: 1363-1380
|
| 23780892 |
Parsons MJ et al.:
Replication of Genome-Wide Association Studies (GWAS) loci for sleep in the British G1219 cohort
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2013
162B: 431-438
|
| 16822851 |
Lucae S et al.:
P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder
Hum. Mol. Genet.
2006
15: 2438-2445
|
| 20186120 |
Richter R et al.:
A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome
EMBO J.
2010
29: 1116-1125
|
| 23260140 |
Mick DU et al.:
MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation
Cell
2012
151: 1528-1541
|
| 21693764 |
Tatham MH et al.:
Comparative proteomic analysis identifies a role for SUMO in protein quality control
Sci Signal
2011
4: RS4
|
| 20603015 |
MacKay C et al.:
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2
Cell
2010
142: 65-76
|
| 10026156 |
Wong V et al.:
Glucocorticoid down-regulation of fascin protein expression is required for the steroid-induced formation of tight junctions and cell-cell interactions in rat mammary epithelial tumor cells
J. Biol. Chem.
1999
274: 5443-5453
|
| 12577067 |
Blagoev B et al.:
A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling
Nat. Biotechnol.
2003
21: 315-318
|
| 19380743 |
Brehme M et al.:
Charting the molecular network of the drug target Bcr-Abl
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 7414-7419
|
| 11013076 |
Slentz-Kesler K et al.:
Identification of the human Mnk2 gene (MKNK2) through protein interaction with estrogen receptor beta
Genomics
2000
69: 63-71
|
| 11527961 |
Lamberti C et al.:
Regulation of beta-catenin function by the IkappaB kinases
J. Biol. Chem.
2001
276
|
| 21204785 |
Smith H et al.:
The role of TBK1 and IKKepsilon in the expression and activation of Pellino 1
Biochem. J.
2011
434: 537-548
|
| 19028959 |
Meyer-Wentrup F et al.:
DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production
J. Leukoc. Biol.
2009
85: 518-525
|
| 22901010 |
Ryan J et al.:
Polymorphisms of estrogen receptors and risk of depression: therapeutic implications
Drugs
2012
72: 1725-1738
|
| 20830301 |
Blaveri E et al.:
Expression profiling of a genetic animal model of depression reveals novel molecular pathways underlying depressive-like behaviours
PLoS ONE
2010
5
|
| 20471630 |
Spijker S et al.:
Stimulated gene expression profiles as a blood marker of major depressive disorder
Biol. Psychiatry
2010
68: 179-186
|
| 21590285 |
Di Cesare Mannelli L et al.:
Antidepressant-like effect of artemin in mice: a mechanism for acetyl-L-carnitine activity on depression
Psychopharmacology (Berl.)
2011
218: 347-356
|
| 18086858 |
Bahmanyar S et al.:
beta-Catenin is a Nek2 substrate involved in centrosome separation
Genes Dev.
2008
22: 91-105
|
| 12386167 |
Chen Y et al.:
Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation
J. Biol. Chem.
2002
277
|
| 24498053 |
Jia W et al.:
Metabotropic glutamate receptor 3 is associated with heroin dependence but not depression or schizophrenia in a chinese population
PLoS ONE
2014
9
|
| 16637010 |
Beasley CL et al.:
Proteomic analysis of the anterior cingulate cortex in the major psychiatric disorders: Evidence for disease-associated changes
Proteomics
2006
6: 3414-3425
|
| 25226551 |
Redei EE et al.:
Blood transcriptomic biomarkers in adult primary care patients with major depressive disorder undergoing cognitive behavioral therapy
Transl Psychiatry
2014
4: E442
|
| 23111923 |
Zheng P et al.:
Identification and validation of urinary metabolite biomarkers for major depressive disorder
Mol. Cell Proteomics
2013
12: 207-214
|
| 27931880 |
et al.:
|
| 20125088 |
et al.:
|
| 27490818 |
Baranyi A et al.:
Branched-Chain Amino Acids as New Biomarkers of Major Depression - A Novel Neurobiology of Mood Disorder
PLoS ONE
2016
11
|
| 22489112 |
Gerile et al.:
Inhibitory action of antidepressants on mouse Betaine/GABA transporter (BGT1) heterologously expressed in cell cultures
Int J Mol Sci
2012
13: 2578-2589
|
| 28752602 |
Qi XR et al.:
Alterations in the steroid biosynthetic pathways in the human prefrontal cortex in mood disorders: A post-mortem study
|
| 20567771 |
Zhang F et al.:
Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry
Mol Biosyst
2010
6: 852-861
|
| 25678776 |
Wen C et al.:
Urine metabolomics in rats after administration of ketamine
Drug Des Devel Ther
2015
9: 717-722
|
| 28917195 |
Black CN et al.:
Uric acid in major depressive and anxiety disorders
J Affect Disord
2018
225: 684-690
|
| 27365148 |
Cunha RA et al.:
How does adenosine control neuronal dysfunction and neurodegeneration?
J. Neurochem.
2016
139: 1019-1055
|
| 29910727 |
Lopez-Cruz L et al.:
Caffeine and Selective Adenosine Receptor Antagonists as New Therapeutic Tools for the Motivational Symptoms of Depression
Front Pharmacol
2018
9: 526
|
| 27502736 |
Zhang C et al.:
Identification of IL6 as a susceptibility gene for major depressive disorder
Sci Rep
2016
6: 31264
|
| 25784130 |
Liu X et al.:
Discovery and validation of plasma biomarkers for major depressive disorder classification based on liquid chromatography-mass spectrometry
J. Proteome Res.
2015
14: 2322-2330
|
| 26903268 |
Gupta M et al. et al.:
TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics
Mol. Psychiatry
2016
21: 1717-1725
|
| 24967945 |
Szebeni A et al.:
Shortened telomere length in white matter oligodendrocytes in major depression: potential role of oxidative stress
Int. J. Neuropsychopharmacol.
2014
17: 1579-1589
|
| 17716746 |
Bremmer MA et al.:
Inflammatory markers in late-life depression: results from a population-based study
J Affect Disord
2008
106: 249-255
|
| 24074516 |
Mota R et al. et al.:
Interleukin-1beta is associated with depressive episode in major depression but not in bipolar disorder
J Psychiatr Res
2013
47: 2011-2014
|
| 30191781 |
Ryan KM et al.:
Peroxisome proliferator-activated receptor gamma co-activator-1 alpha in depression and the response to electroconvulsive therapy
|
| 22057216 |
Chiesa A et al.:
Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder
Eur Arch Psychiatry Clin Neurosci
2012
262: 305-311
|
| 30482883 |
Wang X et al.:
MiR-155 is involved in major depression disorder and antidepressant treatment via targeting SIRT1
|
| 30520409 |
Liu K et al. et al.:
Effect of selective serotonin reuptake inhibitor on prefrontal-striatal connectivity is dependent on the level of TNF-alpha in patients with major depressive disorder
|
| 22683211 |
Li Z et al.:
Venlafaxine inhibits the upregulation of plasma tumor necrosis factor-alpha (TNF-alpha) in the Chinese patients with major depressive disorder: a prospective longitudinal study
Psychoneuroendocrinology
2013
38: 107-114
|
| 26467407 |
Bortolato B et al.:
The Involvement of TNF-alpha in Cognitive Dysfunction Associated with Major Depressive Disorder: An Opportunity for Domain Specific Treatments
Curr Neuropharmacol
2015
13: 558-576
|
| 30584306 |
Huang Y et al. et al.:
Possible association of Firmicutes in the gut microbiota of patients with major depressive disorder
Neuropsychiatr Dis Treat
2018
14: 3329-3337
|
| 26598580 |
Evrensel A et al.:
The Gut-Brain Axis: The Missing Link in Depression
Clin Psychopharmacol Neurosci
2015
13: 239-244
|
| 27288567 |
Aizawa E et al.:
Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder
J Affect Disord
2016
202: 254-257
|
| 25882912 |
Jiang H et al.:
Altered fecal microbiota composition in patients with major depressive disorder
Brain Behav. Immun.
2015
48: 186-194
|
| 15488265 |
Reivich M et al.:
PET brain imaging with [11C](+)McN5652 shows increased serotonin transporter availability in major depression
J Affect Disord
2004
82: 321-327
|
| 28802862 |
Miguel-Hidalgo JJ et al.:
MicroRNA-21: Expression in oligodendrocytes and correlation with low myelin mRNAs in depression and alcoholism
Prog. Neuropsychopharmacol. Biol. Psychiatry
2017
79: 503-514
|
| 20451257 |
Kishi T et al. et al.:
SIRT1 gene is associated with major depressive disorder in the Japanese population
J Affect Disord
2010
126: 167-173
|
| 15841871 |
Klein DN et al.:
Psychopathology in the adolescent and young adult offspring of a community sample of mothers and fathers with major depression
Psychol Med
2005
35: 353-365
|
| 11926937 |
Lieb R et al.:
Parental major depression and the risk of depression and other mental disorders in offspring: a prospective-longitudinal community study
Arch. Gen. Psychiatry
2002
59: 365-374
|
| 16164773 |
Lewinsohn PM et al.:
Psychosocial impairment in offspring of depressed parents
Psychol Med
2005
35: 1493-1503
|
| 12206193 |
Connell AM et al.:
The association between psychopathology in fathers versus mothers and childrens internalizing and externalizing behavior problems: a meta-analysis
Psychol Bull
2002
128: 746-773
|
| 18618621 |
Mrazek DA et al.:
SLC6A4 variation and citalopram response
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2009
150B: 341-351
|
| 25779937 |
Song MF et al.:
CSF miR-16 is decreased in major depression patients and its neutralization in rats induces depression-like behaviors via a serotonin transmitter system
J Affect Disord
2015
178: 25-31
|
| 29163009 |
Higuchi Y et al.:
Regulatory Pathways of Monoamine Oxidase A during Social Stress
Front Neurosci
2017
11: 604
|
| 16324751 |
Jow GM et al.:
Leptin and cholesterol levels are low in major depressive disorder, but high in schizophrenia
J Affect Disord
2006
90: 21-27
|
| 30554862 |
Bopp SK et al. et al.:
Leptin gene polymorphisms are associated with weight gain during lithium augmentation in patients with major depression
Eur Neuropsychopharmacol
2019
29: 211-221
|
| 2839521 |
Wilson C et al.:
Integration of membrane proteins into the endoplasmic reticulum requires GTP
J. Cell Biol.
1988
107: 69-77
|
| 31106520 |
Asadikaram G et al.:
Assessment of hormonal alterations in major depressive disorder: A clinical study
|
| 25734512 |
Malki K et al.:
Identification of genes and gene pathways associated with major depressive disorder by integrative brain analysis of rat and human prefrontal cortex transcriptomes
Transl Psychiatry
2015
5: e519
|
| 25880836 |
Xu F et al.:
Differential co-expression and regulation analyses reveal different mechanisms underlying major depressive disorder and subsyndromal symptomatic depression
BMC Bioinformatics
2015
16: 112
|
| 19111907 |
Shelton RC et al.:
Elevated 5-HT 2A receptors in postmortem prefrontal cortex in major depression is associated with reduced activity of protein kinase A
Neuroscience
2009
158: 1406-1415
|
| 28653857 |
Kopschina Feltes P et al.:
Anti-inflammatory treatment for major depressive disorder: implications for patients with an elevated immune profile and non-responders to standard antidepressant therapy
J. Psychopharmacol. (Oxford)
2017
31: 1149-1165
|
| 18805677 |
Hernandez ME et al.:
Variations in circulating cytokine levels during 52 week course of treatment with SSRI for major depressive disorder
Eur Neuropsychopharmacol
2008
18: 917-924
|
| 31252530 |
Hung YY et al.:
Aberrant Expression of Intracellular let-7e, miR-146a, and miR-155 Correlates with Severity of Depression in Patients with Major Depressive Disorder and Is Ameliorated after Antidepressant Treatment
|
| 24257035 |
Munzer A et al.:
Impact of antidepressants on cytokine production of depressed patients in vitro
Toxins (Basel)
2013
5: 2227-2240
|
| 31195092 |
Enache D et al.:
Markers of central inflammation in major depressive disorder: A systematic review and meta-analysis of studies examining cerebrospinal fluid, positron emission tomography and post-mortem brain tissue
|
| 25827644 |
Seripa D et al.:
Role of the serotonin transporter gene locus in the response to SSRI treatment of major depressive disorder in late life
J. Psychopharmacol. (Oxford)
2015
29: 623-633
|
| 16642436 |
McMahon FJ et al. et al.:
Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment
Am. J. Hum. Genet.
2006
78: 804-814
|
| 26261165 |
Basu A et al.:
Association of serotonin transporter (SLC6A4) and receptor (5HTR1A, 5HTR2A) polymorphisms with response to treatment with escitalopram in patients with major depressive disorder: A preliminary study
Indian J. Med. Res.
2015
142: 40-45
|
| 30221791 |
Demirbugen Oz M et al.:
The relationship between the serotonin 2A receptor gene -1438A/G and 102T/C polymorphisms and citalopram/sertraline-induced nausea in major depressed patients
Hum Psychopharmacol
2018
33: e2673
|
| 21901317 |
Zhong H et al.:
Escitalopram, an antidepressant with an allosteric effect at the serotonin transporter--a review of current understanding of its mechanism of action
Psychopharmacology (Berl.)
2012
219: 1-13
|
| 21422769 |
Karege F et al.:
Alterations in phosphatidylinositol 3-kinase activity and PTEN phosphatase in the prefrontal cortex of depressed suicide victims
Neuropsychobiology
2011
63: 224-231
|
| 25656805 |
Li W et al. et al.:
Genetic association of ACSM1 variation with schizophrenia and major depressive disorder in the Han Chinese population
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2015
168B: 144-149
|
| 24529801 |
O'Dushlaine C et al. et al.:
Rare copy number variation in treatment-resistant major depressive disorder
Biol. Psychiatry
2014
76: 536-541
|
| 15131492 |
Gorman JM et al.:
Efficacy comparison of escitalopram and citalopram in the treatment of major depressive disorder: pooled analysis of placebo-controlled trials
CNS Spectr
2002
7: 40-44
|
| 21621269 |
Aragam N et al.:
Genome-wide association analysis of gender differences in major depressive disorder in the Netherlands NESDA and NTR population-based samples
J Affect Disord
2011
133: 516-521
|
| 27777418 |
Wong ML et al. et al.:
The PHF21B gene is associated with major depression and modulates the stress response
Mol. Psychiatry
2017
22: 1015-1025
|
| 29644388 |
Gibson-Smith D et al.:
The relation between obesity and depressed mood in a multi-ethnic population. The HELIUS study
Soc Psychiatry Psychiatr Epidemiol
2018
53: 629-638
|
| 29922061 |
Gui SW et al.:
Plasma disturbance of phospholipid metabolism in major depressive disorder by integration of proteomics and metabolomics
Neuropsychiatr Dis Treat
2018
14: 1451-1461
|
| 117477 |
author information missing
Increased levels of TRH in cerebrospinal fluid from patients with endogenous depression
Psychoneuroendocrinology
1979
4: 227-235
|
| 23669352 |
Graff M et al. et al.:
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course
Hum. Mol. Genet.
2013
22: 3597-3607
|
| 16247765 |
Novak G et al.:
Increased expression of calcium/calmodulin-dependent protein kinase IIbeta in frontal cortex in schizophrenia and depression
Synapse
2006
59: 61-68
|
| 24058344 |
Lin LC et al.:
Reduced brain somatostatin in mood disorders: a common pathophysiological substrate and drug target?
Front Pharmacol
2013
4: 110
|
| 30828345 |
Yang C et al.:
Whole Exome Sequencing Identifies a Novel Predisposing Gene, MAPKAP1, for Familial Mixed Mood Disorder
Front Genet
2019
10: 74
|
| 25943949 |
Watanabe SY et al.:
Biological tests for major depressive disorder that involve leukocyte gene expression assays
J Psychiatr Res
2015
66-67: 1-6
|
| 29158577 |
Jiang C et al.:
VGF function in depression and antidepressant efficacy
Mol. Psychiatry
2018
23: 1632-1642
|
| 31037515 |
Mizoguchi T et al.:
VGF has Roles in the Pathogenesis of Major Depressive Disorder and Schizophrenia: Evidence from Transgenic Mouse Models
Cell. Mol. Neurobiol.
2019
39: 721-727
|
| 27479909 |
Hyde CL et al.:
Identification of 15 genetic loci associated with risk of major depression in individuals of European descent
Nat. Genet.
2016
48: 1031-1036
|
| 23029476 |
author information missing
article information missing
|
| 29982499 |
Liang C et al.:
Cortical Neuron Migration and Dendrite Morphology are Regulated by Carboxypeptidase E
Cereb. Cortex
2019
29: 2890-2903
|
| 32733030 |
Huls A et al.:
Association between DNA methylation levels in brain tissue and late-life depression in community-based participants
Transl Psychiatry
2020
10: 262
|
| 30076325 |
Woo HI et al.:
Differentially expressed genes related to major depressive disorder and antidepressant response: genome-wide gene expression analysis
Exp. Mol. Med.
2018
50: 92
|
| 21247258 |
Chen P et al.:
Common SNPs in CSF2RB are associated with major depression and schizophrenia in the Chinese Han population
World J Biol Psychiatry
2011
12: 233-238
|
| 26839717 |
Dwivedi Y et al.:
Altered ERK1/2 Signaling in the Brain of Learned Helpless Rats: Relevance in Vulnerability to Developing Stress-Induced Depression
Neural Plast
2016
2016
|
| 17499413 |
Saab YB et al.:
Renin-angiotensin-system gene polymorphisms and depression
Prog Neuropsychopharmacol Biol Psychiatry
2007
31: 1113-1118
|
| 19617918 |
Otaegui D et al.:
Differential micro RNA expression in PBMC from multiple sclerosis patients
PLoS ONE
2009
4: E6309
|
| 19823682 |
Keller A et al.:
Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls
PLoS ONE
2009
4: E7440
|
| 19838199 |
Du C et al.:
MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis
Nat. Immunol.
2009
10: 1252-1259
|
| 19153172 |
Mattsson N et al.:
Reduced cerebrospinal fluid BACE1 activity in multiple sclerosis
Mult. Scler.
2009
15: 448-454
|
| 22855462 |
Grant JL et al.:
Reversal of Paralysis and Reduced Inflammation from Peripheral Administration of beta-Amyloid in TH1 and TH17 Versions of Experimental Autoimmune Encephalomyelitis
Sci Transl Med
2012
4: 145RA105
|
| 19494326 |
Nath N et al.:
Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis
J. Immunol.
2009
182: 8005-8014
|
| 22906614 |
Niino M et al.:
Risk factors for multiple sclerosis: decreased vitamin D level and remote Epstein-Barr virus infection in the pre-clinical phase of multiple sclerosis
J. Neurol. Neurosurg. Psychiatr.
2012
83: 1135
|
| 22846497 |
Toubi E et al.:
Laquinimod modulates B cells and their regulatory effects on T cells in Multiple Sclerosis
J. Neuroimmunol.
2012
251: 45-54
|
| 20684995 |
Wegner C et al.:
Laquinimod interferes with migratory capacity of T cells and reduces IL-17 levels, inflammatory demyelination and acute axonal damage in mice with experimental autoimmune encephalomyelitis
J. Neuroimmunol.
2010
227: 133-143
|
| 22749337 |
Aharoni R et al.:
Oral treatment with laquinimod augments regulatory T-cells and brain-derived neurotrophic factor expression and reduces injury in the CNS of mice with experimental autoimmune encephalomyelitis
J. Neuroimmunol.
2012
251: 14-24
|
| 22217618 |
OCarroll CB et al.:
Is donepezil effective for multiple sclerosis-related cognitive dysfunction? A critically appraised topic
Neurologist
2012
18: 51-54
|
| 18973065 |
Shaygannejad V et al.:
Effects of rivastigmine on memory and cognition in multiple sclerosis
Can J Neurol Sci
2008
35: 476-481
|
| 22524989 |
Wang J et al.:
Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression of T cell-mediated neuronal inflammation in mice
Exp. Neurol.
2012
236: 79-87
|
| 22871633 |
Rizzo R et al.:
Altered natural killer cells response to herpes virus infection in multiple sclerosis involves KIR2DL2 expression
J. Neuroimmunol.
2012
251: 55-64
|
| 22884548 |
Inkster B et al.:
Histone deacetylase gene variants predict brain volume changes in multiple sclerosis
Neurobiol. Aging
2013
34: 238-247
|
| 22194214 |
Varade J et al.:
Replication study of 10 genes showing evidence for association with multiple sclerosis: validation of TMEM39A, IL12B and CBLB [correction of CLBL] genes
Mult. Scler.
2012
18: 959-965
|
| 18038905 |
Min K et al.:
Immunosuppressive effect of silibinin in experimental autoimmune encephalomyelitis
Arch. Pharm. Res.
2007
30: 1265-1272
|
| 23595275 |
Boyd A et al.:
Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models
Acta Neuropathol.
2013
125: 841-859
|
| 21163235 |
Guerrero AL et al.:
Influence of APOE gene polymorphisms on interferon-beta treatment response in multiple sclerosis
Neurologia
2011
26: 137-142
|
| 23469939 |
Bakshi S et al.:
Gene expression analysis reveals functional pathways of glatiramer acetate activation
Expert Opin. Ther. Targets
2013
17: 351-362
|
| 21710707 |
Csepany T et al.:
[Current treatment of multiple sclerosis]
Lege Artis Med
2011
21: 97-104
|
| 23141166 |
Begum-Haque S et al.:
Glatiramer acetate biases dendritic cells towards an anti-inflammatory phenotype by modulating OPN, IL-17, and RORgammat responses and by increasing IL-10 production in experimental allergic encephalomyelitis
J. Neuroimmunol.
2013
254: 117-124
|
| 22992073 |
Gold R et al.:
Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis
N. Engl. J. Med.
2012
367: 1098-1107
|
| 22190364 |
Patsopoulos NA et al.:
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci
Ann. Neurol.
2011
70: 897-912
|
| 22992072 |
Fox RJ et al.:
Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis
N. Engl. J. Med.
2012
367: 1087-1097
|
| 23552370 |
Kurnellas MP et al.:
Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation
Sci Transl Med
2013
5: 179RA42
|
| 23034287 |
Arnason BG et al.:
Mechanisms of action of adrenocorticotropic hormone and other melanocortins relevant to the clinical management of patients with multiple sclerosis
Mult. Scler.
2013
19: 130-136
|
| 23482896 |
Ross AP et al.:
Multiple sclerosis, relapses, and the mechanism of action of adrenocorticotropic hormone
Front Neurol
2013
4: 21
|
| 23609781 |
Rommer PS et al.:
Management of secondary progressive multiple sclerosis: prophylactic treatment-past, present, and future aspects
Curr Treat Options Neurol
2013
15: 241-258
|
| 23732529 |
Wiendl H et al.:
Modulation of IL-2Ralpha with daclizumab for treatment of multiple sclerosis
Nat Rev Neurol
2013
9: 394-404
|
| 23921512 |
Lourbopoulos A et al.:
Coexistence of Multiple Sclerosis and Ankylosing Spondylitis: Report of Two Cases
Eur. Neurol.
2013
70: 149-154
|
| 23250765 |
Solaro C et al.:
Pain and multiple sclerosis: pathophysiology and treatment
Curr Neurol Neurosci Rep
2013
13: 320
|
| 15735653 |
Greter M et al.:
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
Nat. Med.
2005
11: 328-334
|
| 29651206 |
Atya HB et al.:
Urinary Urea, Uric Acid and Hippuric Acid as Potential Biomarkers in Multiple Sclerosis Patients
Indian J Clin Biochem
2018
33: 163-170
|
| 31081484 |
Graves JS et al. et al.:
Vitamin D genes influence MS relapses in children
|
| 30616226 |
Mazdeh M et al.:
A single nucleotide polymorphism in the metabotropic glutamate receptor 7 gene is associated with multiple sclerosis in Iranian population
Mult Scler Relat Disord
2019
28: 189-192
|
| 19525955 |
author information missing
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
Nat. Genet.
2009
41: 824-828
|
| 15729363 |
Cunningham S et al.:
Haplotype analysis of the preprotachykinin-1 (TAC1) gene in multiple sclerosis
Genes Immun.
2005
6: 265-270
|
| 28322999 |
Farrokhi M et al.:
Sema3A and multiple sclerosis
Gene
2017
615: 41
|
| 29961995 |
Valko PO et al.:
In search of cerebrospinal fluid biomarkers of fatigue in multiple sclerosis: A proteomics study
J Sleep Res
2019
28
|
| 31604244 |
author information missing
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
|
| 11958827 |
Mann MB et al.:
Association between the phenylethanolamine N-methyltransferase gene and multiple sclerosis
J. Neuroimmunol.
2002
124: 101-105
|
| 21833088 |
Sawcer S et al. et al.:
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Nature
2011
476: 214-219
|
| 29470604 |
Okada R et al.:
Cathepsin H deficiency in mice induces excess Th1 cell activation and early-onset of EAE though impairment of toll-like receptor 3 cascade
Inflamm Res
2018
67: 371-374
|
| 17645239 |
Satoh J et al.:
Human astrocytes express aquaporin-1 and aquaporin-4 in vitro and in vivo
Neuropathology
2007
27: 245-256
|
| 32559700 |
Nali LH et al.:
Whole transcriptome analysis of multiple Sclerosis patients reveals active inflammatory profile in relapsing patients and downregulation of neurological repair pathways in secondary progressive cases
Mult Scler Relat Disord
2020
44
|
| 29392731 |
Zeiser R et al.:
Immune modulatory effects of statins
Immunology
2018
154: 69-75
|
| 19525953 |
De Jager PL et al. et al.:
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
Nat Genet
2009
41: 776-782
|
| 18482773 |
author information missing
article information missing
|
| 39767677 |
author information missing
article information missing
|
| 10739162 |
author information missing
article information missing
|
| 34934004 |
author information missing
article information missing
|
| 26447191 |
Moroy T et al.:
From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation
Blood
2015
126: 2561-2569
|
| 19346496 |
Horman SR et al.:
Gfi1 integrates progenitor versus granulocytic transcriptional programming
Blood
2009
113: 5466-5475
|
| 12778173 |
Person RE et al.:
Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2
Nat. Genet.
2003
3: 308-312
|
| 26567890 |
Nustede R et al.:
ELANE mutant-specific activation of different UPR pathways in congenital neutropenia
Br. J. Haematol.
2016
172: 219-227
|
| 17761833 |
Grenda DS et al.:
Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis
Blood
2007
110: 4179-4187
|
| 24459464 |
author information missing
article information missing
|
| 24910990 |
Hellewell AL et al.:
Analysis of familial hemophagocytic lymphohistiocytosis type 4 (FHL-4) mutant proteins reveals that S-acylation is required for the function of syntaxin 11 in natural killer cells
PLoS ONE
2014
9
|
| 23009155 |
Beaussant Cohen S et al.:
Description and outcome of a cohort of 8 patients with WHIM syndrome from the French Severe Chronic Neutropenia Registry
Orphanet J Rare Dis
2012
7: 71
|
| 21178277 |
Bachelerie F et al.:
CXCL12/CXCR4-axis dysfunctions: Markers of the rare immunodeficiency disorder WHIM syndrome
Dis. Markers
2010
29: 189-198
|
| 22174160 |
Nehme NT et al.:
MST1 mutations in autosomal recessive primary immunodeficiency characterized by defective naive T-cell survival
Blood
2012
119: 3458-3468
|
| 20620114 |
Summers C et al.:
Neutrophil kinetics in health and disease
Trends Immunol.
2010
31: 318-324
|
| 23820376 |
author information missing
article information missing
|
| 25766564 |
author information missing
article information missing
|
| 19182797 |
author information missing
article information missing
|
| 24750412 |
Arikoglu T et al.:
A novel G6PC3 gene mutation in severe congenital neutropenia: pancytopenia and variable bone marrow phenotype can also be part of this syndrome
Eur. J. Haematol.
2015
94: 79-82
|
| 29914977 |
author information missing
article information missing
|
| 22377092 |
Wang KS et al.:
ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies
Drug Alcohol Depend
2012
124: 325-332
|
| 21307845 |
Clarke TK et al.:
KCNJ6 is associated with adult alcohol dependence and involved in gene x early life stress interactions in adolescent alcohol drinking
Neuropsychopharmacology
2011
36: 1142-1148
|
| 23820610 |
Jaremek M et al.:
Alcohol-induced metabolomic differences in humans
Transl Psychiatry
2013
3: E276
|
| 18618593 |
Chen AC et al.:
Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2009
150B: 359-368
|
| 11956970 |
Hasegawa Y et al.:
Association of a polymorphism of the serotonin 1B receptor gene and alcohol dependence with inactive aldehyde dehydrogenase-2
J Neural Transm
2002
109: 513-521
|
| 31002879 |
Lee YJ et al.:
The association between alcohol metabolism and genetic variants of ADH1A, SRPRB, and PGM1 in Korea
Alcohol
2019
79: 137-145
|
| 16126915 |
Maul B et al.:
Central angiotensin II controls alcohol consumption via its AT1 receptor
FASEB J
2005
19: 1474-1481
|
| 14623284 |
Millar JK et al.:
Yeast two-hybrid screens implicate DISC1 in brain development and function.
Biochem. Biophys. Res. Commun.
2003
311: 1019-1025
|
| 16980962 |
Smith WW et al.:
Kinase activity of mutant LRRK2 mediates neuronal toxicity.
Nat. Neurosci.
2006
9: 1231-1233
|
| 16750377 |
Greggio E et al.:
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
Neurobiol. Dis.
2006
23: 329-341
|
| 19770575 |
Alegre-Abarrategui J et al.:
Parkinson disease, LRRK2 and the endocytic-autophagic pathway.
Autophagy
2009
5: 1208-1210
|
| 19682553 |
Pan T et al.:
Rapamycin protects against rotenone-induced apoptosis through autophagy induction
Neuroscience
2009
164: 541-551
|
| 18395527 |
Gomez-Lazaro M et al.:
6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells.
Free Radic. Biol. Med.
2008
44: 1960-1969
|
| 11057907 |
Deng L et al.:
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain.
Cell
2000
103: 351-361
|
| 2451115 |
Ohara K et al.:
The interaction between D-2 dopamine receptors and GTP-binding proteins.
Mol. Pharmacol.
1988
33: 290-296
|
| 8327893 |
Taussig R et al.:
Inhibition of adenylyl cyclase by Gi alpha.
Science
1993
261: 218-221
|
| 2270483 |
Li YS et al.:
Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity.
Science
1990
250: 1690-1694
|
| 9457173 |
Missale C et al.:
Dopamine receptors: from structure to function.
Physiol. Rev.
1998
78: 189-225
|
| 9140089 |
Hanoune J et al.:
Adenylyl cyclases: structure, regulation and function in an enzyme superfamily.
Mol. Cell. Endocrinol.
1997
128: 179-194
|
| 9888852 |
Bhalla US et al.:
Emergent properties of networks of biological signaling pathways.
Science
1999
283: 381-387
|
| 17608927 |
Ciani L et al.:
c-Jun N-terminal kinase (JNK) cooperates with Gsk3beta to regulate Dishevelled-mediated microtubule stability.
BMC Cell Biol.
2007
8: 27
|
| 10706604 |
Meng K et al.:
Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zeta.
Proc. Natl. Acad. Sci. U.S.A.
2000
97: 2603-2608
|
| 15121180 |
Hienola A et al.:
HB-GAM inhibits proliferation and enhances differentiation of neural stem cells.
Mol. Cell. Neurosci.
2004
26: 75-88
|
| 18727926 |
Gramage E et al.:
Pleiotrophin prevents cocaine-induced toxicity in vitro.
Eur. J. Pharmacol.
2008
595: 35-38
|
| 18727926 |
Gramage E et al.:
Pleiotrophin prevents cocaine-induced toxicity in vitro
Eur. J. Pharmacol.
2008
595: 35-38
|
| 2205396 |
McMahon AP et al.:
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain.
Cell
1990
62: 1073-1085
|
| 15522889 |
Castelo-Branco G et al.:
GSK-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons.
J. Cell. Sci.
2004
117: 5731-5737
|
| 16353915 |
Svenningsson P et al.:
DARPP-32 mediates the actions of multiple drugs of abuse.
AAPS J
2005
7: E353-E360
|
| 19788394 |
Azizi H et al.:
Dehydroepiandrosterone stimulates neurogenesis in mouse embryonal carcinoma cell- and human embryonic stem cell-derived neural progenitors and induces dopaminergic neurons
Stem Cells Dev.
2010
19: 809-818
|
| 11931644 |
Hudmon A et al.:
Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II
Biochem. J.
2002
364: 593-611
|
| 12874605 |
Miyoshi K et al.:
Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth
Mol. Psychiatry
2003
8: 685-694
|
| 12874605 |
Miyoshi K et al.:
Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth.
Mol. Psychiatry
2003
8: 685-694
|
| 20049900 |
Lee HS et al.:
Foxa2 and Nurr1 synergistically yield A9 nigral dopamine neurons exhibiting improved differentiation, function, and cell survival.
Stem Cells
2010
28: 501-512
|
| 17664024 |
Matsuzaki S et al.:
Molecular mechanism of schizophrenia with reference to disrupted-in-schizophrenia 1 (DISC1).
Neurochem. Int.
2007
51: 165-172
|
| 17389905 |
Hattori T et al.:
A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth.
Mol. Psychiatry
2007
12: 398-407
|
| 17389905 |
Hattori T et al. et al.:
A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth
Mol. Psychiatry
2007
12: 398-407
|
| 20106970 |
Courtois ET et al.:
In vitro and in vivo enhanced generation of human A9 dopamine neurons from neural stem cells by Bcl-XL.
J. Biol. Chem.
2010
285: 9881-9897
|
| 12506198 |
Ozeki Y et al.:
Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth.
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 289-294
|
| 10862698 |
Husi H et al.:
Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.
Nat. Neurosci.
2000
3: 661-669
|
| 8139656 |
Sheng M et al.:
Changing subunit composition of heteromeric NMDA receptors during development of rat cortex.
Nature
1994
368: 144-147
|
| 12191494 |
Thompson CL et al.:
Immunohistochemical localization of N-methyl-D-aspartate receptor subunits in the adult murine hippocampal formation: evidence for a unique role of the NR2D subunit.
Brain Res. Mol. Brain Res.
2002
102: 55-61
|
| 9778245 |
Stambolic V et al.:
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN.
Cell
1998
95: 29-39
|
| 15014970 |
Lorenzetti D et al.:
The neurological mutant quaking(viable) is Parkin deficient
Mamm. Genome
2004
15: 210-217
|
| 21092858 |
Ninkovic J et al.:
The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin alphaA
Neuron
2010
68: 682-694
|
| 18562615 |
Brill MS et al.:
A dlx2- and pax6-dependent transcriptional code for periglomerular neuron specification in the adult olfactory bulb
J. Neurosci.
2008
28: 6439-6452
|
| 16098226 |
Cooper ST et al.:
A screen for proteins that interact with PAX6: C-terminal mutations disrupt interaction with HOMER3, DNCL1 and TRIM11
BMC Genet.
2005
6: 43
|
| 11350962 |
Planque N et al.:
Specific Pax-6/microphthalmia transcription factor interactions involve their DNA-binding domains and inhibit transcriptional properties of both proteins
J. Biol. Chem.
2001
276
|
| 12324464 |
Tominaga T et al.:
The Rho GTPase effector protein, mDia, inhibits the DNA binding ability of the transcription factor Pax6 and changes the pattern of neurite extension in cerebellar granule cells through its binding to Pax6
J. Biol. Chem.
2002
277
|
| 16407227 |
Kim EA et al.:
Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2
J. Biol. Chem.
2006
281: 7489-7497
|
| 10506141 |
Hussain MA et al.:
Glucagon gene transcription activation mediated by synergistic interactions of pax-6 and cdx-2 with the p300 co-activator
J. Biol. Chem.
1999
274
|
| 10359315 |
Cvekl A et al.:
Pax-6 interactions with TATA-box-binding protein and retinoblastoma protein
Invest. Ophthalmol. Vis. Sci.
1999
40: 1343-1350
|
| 11069920 |
Mikkola I et al.:
Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins
J. Biol. Chem.
2001
276: 4109-4118
|
| 15143176 |
Ploski JE et al.:
Paired-type homeodomain transcription factors are imported into the nucleus by karyopherin 13
Mol. Cell. Biol.
2004
24: 4824-4834
|
| 18656177 |
Bonnefont J et al.:
Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development
Am. J. Hum. Genet.
2008
83: 208-218
|
| 17251190 |
Grocott T et al.:
The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter
Nucleic Acids Res.
2007
35: 890-901
|
| 12710953 |
Aota S et al.:
Pax6 autoregulation mediated by direct interaction of Pax6 protein with the head surface ectoderm-specific enhancer of the mouse Pax6 gene
Dev. Biol.
2003
257: 1-13
|
| 11036080 |
Kataoka K et al.:
A set of Hox proteins interact with the Maf oncoprotein to inhibit its DNA binding, transactivation, and transforming activities
J. Biol. Chem.
2001
276: 819-826
|
| 16675956 |
Yang Y et al.:
Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin
EMBO J.
2006
25: 2107-2118
|
| 16582099 |
Wissmuller S et al.:
The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors
Nucleic Acids Res.
2006
34: 1735-1744
|
| 20943817 |
Wolf G et al.:
The activation of the rat insulin gene II by BETA2 and PDX-1 in rat insulinoma cells is repressed by Pax6
Mol. Endocrinol.
2010
24: 2331-2342
|
| 9224716 |
Sander M et al.:
Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development
Genes Dev.
1997
11: 1662-1673
|
| 19917615 |
Zhang Y et al.:
The beta subunit of voltage-gated Ca2+ channels interacts with and regulates the activity of a novel isoform of Pax6
J. Biol. Chem.
2010
285: 2527-2536
|
| 19790232 |
Shyr CR et al.:
Tumor suppressor PAX6 functions as androgen receptor co-repressor to inhibit prostate cancer growth
Prostate
2010
70: 190-199
|
| 17277739 |
Spence JR et al.:
Retina regeneration in the chick embryo is not induced by spontaneous Mitf downregulation but requires FGF/FGFR/MEK/Erk dependent upregulation of Pax6
Mol. Vis.
2007
13: 57-65
|
| 10329718 |
Mikkola I et al.:
Phosphorylation of the transactivation domain of Pax6 by extracellular signal-regulated kinase and p38 mitogen-activated protein kinase
J. Biol. Chem.
1999
274
|
| 15161828 |
Zaniolo K et al.:
Expression of the alpha4 integrin subunit gene promoter is modulated by the transcription factor Pax-6 in corneal epithelial cells
Invest. Ophthalmol. Vis. Sci.
2004
45: 1692-1704
|
| 9933606 |
Ritz-Laser B et al.:
Pax-6 and Cdx-2/3 interact to activate glucagon gene expression on the G1 control element
J. Biol. Chem.
1999
274: 4124-4132
|
| 19146846 |
Tetreault N et al.:
The LIM homeobox transcription factor Lhx2 is required to specify the retina field and synergistically cooperates with Pax6 for Six6 trans-activation
Dev. Biol.
2009
327: 541-550
|
| 17374606 |
Yan Q et al.:
Protein phosphatase-1 modulates the function of Pax-6, a transcription factor controlling brain and eye development
J. Biol. Chem.
2007
282
|
| 20628604 |
Meier-Stiegen F et al.:
Activated Notch1 target genes during embryonic cell differentiation depend on the cellular context and include lineage determinants and inhibitors
PLoS ONE
2010
5
|
| 19208436 |
Riesenberg AN et al.:
Pax6 regulation of Math5 during mouse retinal neurogenesis
Genesis
2009
47: 175-187
|
| 20177825 |
Tripathi R et al.:
Interaction of Pax6 with SPARC and p53 in brain of mice indicates Smad3 dependent auto-regulation
J. Mol. Neurosci.
2010
41: 397-403
|
| 18436815 |
Davis J et al.:
Gene expression of the mouse corneal crystallin Aldh3a1: activation by Pax6, Oct1, and p300
Invest. Ophthalmol. Vis. Sci.
2008
49: 1814-1826
|
| 18287938 |
Wen J et al.:
Pax6 directly modulate Sox2 expression in the neural progenitor cells
Neuroreport
2008
19: 413-417
|
| 16118513 |
Lengler J et al.:
Agonistic and antagonistic action of AP2, Msx2, Pax6, Prox1 AND Six3 in the regulation of Sox2 expression
Ophthalmic Res.
2005
37: 301-309
|
| 12783797 |
Scardigli R et al.:
Direct and concentration-dependent regulation of the proneural gene Neurogenin2 by Pax6
Development
2003
130: 3269-3281
|
| 20404570 |
Wu J et al.:
miR-129 regulates cell proliferation by downregulating Cdk6 expression
Cell Cycle
2010
9: 1809-1818
|
| 19965369 |
Decembrini S et al.:
MicroRNAs couple cell fate and developmental timing in retina
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 18189265 |
Liao R et al.:
MicroRNAs play a role in the development of human hematopoietic stem cells.
J. Cell. Biochem.
2008
104: 805-817
|
| 19913497 |
Simion A et al.:
MiR-495 and miR-218 regulate the expression of the Onecut transcription factors HNF-6 and OC-2
Biochem. Biophys. Res. Commun.
2010
391: 293-298
|
| 20346763 |
Ross SE et al.:
Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice
Neuron
2010
65: 886-898
|
| 17092954 |
Feng L et al.:
Requirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retina
Development
2006
133: 4815-4825
|
| 8552091 |
Peyton M et al.:
BETA3, a novel helix-loop-helix protein, can act as a negative regulator of BETA2 and MyoD-responsive genes
Mol. Cell. Biol.
1996
16: 626-633
|
| 8552091 |
Peyton M et al.:
BETA3, a novel helix-loop-helix protein, can act as a negative regulator of BETA2 and MyoD-responsive genes
Mol. Cell. Biol.
1996
16: 626-633
|
| 18199774 |
Liu H et al.:
NeuroD1 regulates expression of thyroid hormone receptor 2 and cone opsins in the developing mouse retina
J. Neurosci.
2008
28: 749-756
|
| 16202708 |
Hand R et al.:
Phosphorylation of Neurogenin2 specifies the migration properties and the dendritic morphology of pyramidal neurons in the neocortex
Neuron
2005
48: 45-62
|
| 10757813 |
Huang HP et al.:
Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3
Mol. Cell. Biol.
2000
20: 3292-3307
|
| 15342472 |
Skowronska-Krawczyk D et al.:
Highly specific interactions between bHLH transcription factors and chromatin during retina development
Development
2004
131: 4447-4454
|
| 14517545 |
Bylund M et al.:
Vertebrate neurogenesis is counteracted by Sox1-3 activity
Nat. Neurosci.
2003
6: 1162-1168
|
| 12213201 |
Xu ZP et al.:
Functional and structural characterization of the human gene BHLHB5, encoding a basic helix-loop-helix transcription factor
Genomics
2002
80: 311-318
|
| 18252719 |
Babu DA et al.:
Pdx1 and BETA2/NeuroD1 participate in a transcriptional complex that mediates short-range DNA looping at the insulin gene
J. Biol. Chem.
2008
283: 8164-8172
|
| 16251211 |
Jung CG et al.:
Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation
Development
2005
132: 5137-5145
|
| 14752053 |
Kim JY et al.:
Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD
Mol. Endocrinol.
2004
18: 776-790
|
| 9512516 |
Mutoh H et al.:
The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells
Genes Dev.
1998
12: 820-830
|
| 10848608 |
Poulin G et al.:
Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family
Mol. Cell. Biol.
2000
20: 4826-4837
|
| 9343431 |
Poulin G et al.:
NeuroD1/beta2 contributes to cell-specific transcription of the proopiomelanocortin gene
Mol. Cell. Biol.
1997
17: 6673-6682
|
| 10101232 |
Noma T et al.:
Overexpression of NeuroD in PC12 cells alters morphology and enhances expression of the adenylate kinase isozyme 1 gene
Brain Res. Mol. Brain Res.
1999
67: 53-63
|
| 16569215 |
Liu WD et al.:
INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases
Biochem. J.
2006
397: 169-177
|
| 20448145 |
Mwangi SM et al.:
Glial cell line-derived neurotrophic factor enhances neurogenin3 gene expression and beta-cell proliferation in the developing mouse pancreas
Am. J. Physiol. Gastrointest. Liver Physiol.
2010
299: G283-G292
|
| 19759004 |
Anderson KR et al.:
Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3
J. Biol. Chem.
2009
284
|
| 19701198 |
Kuwabara T et al.:
Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis
Nat. Neurosci.
2009
12: 1097-1105
|
| 19619559 |
Zhang H et al.:
The LIM-homeodomain protein ISL1 activates insulin gene promoter directly through synergy with BETA2
J. Mol. Biol.
2009
392: 566-577
|
| 19264802 |
Yang Y et al.:
The Kruppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription
Nucleic Acids Res.
2009
37: 2529-2538
|
| 18201699 |
Revet I et al.:
The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta-Notch pathway in neuroblastoma
Exp. Cell Res.
2008
314: 707-719
|
| 16055439 |
Amemiya-Kudo M et al.:
Sterol regulatory element-binding proteins activate insulin gene promoter directly and indirectly through synergy with BETA2/E47
J. Biol. Chem.
2005
280
|
| 15701640 |
Batsche E et al.:
Retinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcription
J. Biol. Chem.
2005
280
|
| 15665000 |
Zhao L et al.:
The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription
J. Biol. Chem.
2005
280
|
| 15254898 |
Morgan R et al.:
Pax6 is a direct, positively regulated target of the circadian gene Clock
Dev. Dyn.
2004
230: 643-650
|
| 12962539 |
Marsich E et al.:
The PAX6 gene is activated by the basic helix-loop-helix transcription factor NeuroD/BETA2
Biochem. J.
2003
376: 707-715
|
| 12810726 |
Khoo S et al.:
Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells.
J. Biol. Chem.
2003
278
|
| 12482979 |
Ray SK et al.:
Novel transcriptional potentiation of BETA2/NeuroD on the secretin gene promoter by the DNA-binding protein Finb/RREB-1.
Mol. Cell. Biol.
2003
23: 259-271
|
| 11981044 |
Kim JW et al.:
Transactivation of the mouse sulfonylurea receptor I gene by BETA2/NeuroD.
Mol. Endocrinol.
2002
16: 1097-1107
|
| 10859489 |
Tremblay JJ et al.:
Transcriptional properties of Ptx1 and Ptx2 isoforms.
Neuroendocrinology
2000
71: 277-286
|
| 10629047 |
Ohneda K et al.:
The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter.
Mol. Cell. Biol.
2000
20: 900-911
|
| 12881483 |
Marcora E et al.:
Stimulation of NeuroD activity by huntingtin and huntingtin-associated proteins HAP1 and MLK2.
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 9578-9583
|
| 11788592 |
Ratineau C et al.:
Cyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroD.
J. Biol. Chem.
2002
277: 8847-8853
|
| 19389376 |
Henke RM et al.:
Ascl1 and Neurog2 form novel complexes and regulate Delta-like3 (Dll3) expression in the neural tube.
Dev. Biol.
2009
328: 529-540
|
| 19646530 |
Aaker JD et al.:
Feedback regulation of NEUROG2 activity by MTGR1 is required for progression of neurogenesis.
Mol. Cell. Neurosci.
2009
42: 267-277
|
| 21169561 |
Ichi S et al.:
Role of Pax3 acetylation in the regulation of Hes1 and Neurog2
Mol. Biol. Cell
2011
22: 503-512
|
| 19059340 |
Ochiai W et al.:
Periventricular notch activation and asymmetric Ngn2 and Tbr2 expression in pair-generated neocortical daughter cells.
Mol. Cell. Neurosci.
2009
40: 225-233
|
| 18690213 |
Heng JI et al.:
Neurogenin 2 controls cortical neuron migration through regulation of Rnd2.
Nature
2008
455: 114-118
|
| 16432194 |
Ge W et al.:
Coupling of cell migration with neurogenesis by proneural bHLH factors.
Proc. Natl. Acad. Sci. U.S.A.
2006
103: 1319-1324
|
| 16425218 |
Ota M et al.:
BMP and FGF-2 regulate neurogenin-2 expression and the differentiation of sensory neurons and glia.
Dev. Dyn.
2006
235: 646-655
|
| 12399315 |
Dubreuil V et al.:
The role of Phox2b in synchronizing pan-neuronal and type-specific aspects of neurogenesis.
Development
2002
129: 5241-5253
|
| 20214951 |
Aaker JD et al.:
Interaction of MTG family proteins with NEUROG2 and ASCL1 in the developing nervous system.
Neurosci. Lett.
2010
474: 46-51
|
| 19641016 |
Henke RM et al.:
Neurog2 is a direct downstream target of the Ptf1a-Rbpj transcription complex in dorsal spinal cord.
Development
2009
136: 2945-2954
|
| 17060451 |
Heimbucher T et al.:
Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors.
Mol. Cell. Biol.
2007
27: 340-351
|
| 19736326 |
Agoston Z et al.:
Meis2 competes with the Groucho co-repressor Tle4 for binding to Otx2 and specifies tectal fate without induction of a secondary midbrain-hindbrain boundary organizer.
Development
2009
136: 3311-3322
|
| 20530484 |
Masuda T et al.:
SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium.
J. Biol. Chem.
2010
285
|
| 19401468 |
Larder R et al.:
Otx2 induction of the gonadotropin-releasing hormone promoter is modulated by direct interactions with Grg co-repressors.
J. Biol. Chem.
2009
284
|
| 18385377 |
Danno H et al.:
Molecular links among the causative genes for ocular malformation: Otx2 and Sox2 coregulate Rax expression.
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 5408-5413
|
| 9556594 |
Guazzi S et al.:
Regulatory interactions between the human HOXB1, HOXB2, and HOXB3 proteins and the upstream sequence of the Otx2 gene in embryonal carcinoma cells.
J. Biol. Chem.
1998
273
|
| 9174161 |
Gherzi R et al.:
The human homeodomain protein OTX2 binds to the human tenascin-C promoter and trans-represses its activity in transfected cells.
DNA Cell Biol.
1997
16: 559-567
|
| 15890343 |
Kimura K et al.:
Functional analysis of transcriptional repressor Otx3/Dmbx1.
FEBS Lett.
2005
579: 2926-2932
|
| 10623575 |
Nakano T et al.:
OTX2 directly interacts with LIM1 and HNF-3beta.
Biochem. Biophys. Res. Commun.
2000
267: 64-70
|
| 12663655 |
Martinez-Morales JR et al.:
OTX2 activates the molecular network underlying retina pigment epithelium differentiation.
J. Biol. Chem.
2003
278
|
| 8918878 |
Agulnick AD et al.:
Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins.
Nature
1996
384: 270-272
|
| 15857913 |
Nishioka N et al.:
Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.
Development
2005
132: 2535-2546
|
| 21281489 |
Drews C et al.:
The nephrogenic potential of the transcription factors osr1, osr2, hnf1b, lhx1 and pax8 assessed in Xenopus animal caps.
BMC Dev. Biol.
2011
11: 5
|
| 12642491 |
Foucher I et al.:
Joint regulation of the MAP1B promoter by HNF3beta/Foxa2 and Engrailed is the result of a highly conserved mechanism for direct interaction of homeoproteins and Fox transcription factors.
Development
2003
130: 1867-1876
|
| 18160702 |
Mattar P et al.:
Basic helix-loop-helix transcription factors cooperate to specify a cortical projection neuron identity.
Mol. Cell. Biol.
2008
28: 1456-1469
|
| 10669750 |
Kobayashi A et al.:
A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domain.
Mol. Cell. Biol.
2000
20: 1733-1746
|
| 11751862 |
Morii E et al.:
Interaction and cooperation of mi transcription factor (MITF) and myc-associated zinc-finger protein-related factor (MAZR) for transcription of mouse mast cell protease 6 gene.
J. Biol. Chem.
2002
277: 8566-8571
|
| 10713105 |
Fedele M et al.:
A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor.
J. Biol. Chem.
2000
275: 7894-7901
|
| 11719514 |
Pero R et al.:
PATZ attenuates the RNF4-mediated enhancement of androgen receptor-dependent transcription.
J. Biol. Chem.
2002
277: 3280-3285
|
| 12706836 |
Abramovitch S et al.:
BRCA1-Sp1 interactions in transcriptional regulation of the IGF-IR gene.
FEBS Lett.
2003
541: 149-154
|
| 12569082 |
Zhang X et al.:
Suppression of HGF receptor gene expression by oxidative stress is mediated through the interplay between Sp1 and Egr-1.
Am. J. Physiol. Renal Physiol.
2003
284
|
| 11274368 |
Gartel AL et al.:
Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3.
Proc. Natl. Acad. Sci. U.S.A.
2001
98: 4510-4515
|
| 15691849 |
Ichimura T et al.:
Transcriptional repression and heterochromatin formation by MBD1 and MCAF/AM family proteins.
J. Biol. Chem.
2005
280
|
| 15674334 |
Sengupta S et al.:
Tumor suppressor p53 represses transcription of RECQ4 helicase.
Oncogene
2005
24: 1738-1748
|
| 15780936 |
Koshiji M et al.:
HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression.
Mol. Cell
2005
17: 793-803
|
| 11839795 |
Li SH et al.:
Interaction of Huntington disease protein with transcriptional activator Sp1.
Mol. Cell. Biol.
2002
22: 1277-1287
|
| 15550242 |
Bond GL et al.:
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans.
Cell
2004
119: 591-602
|
| 15019994 |
Xu X et al.:
Transcription factor accessibility and histone acetylation of the progesterone receptor gene differs between parental MCF-7 cells and a subline that has lost progesterone receptor expression.
Gene
2004
328: 143-151
|
| 15619633 |
Nebbioso A et al.:
Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells.
Nat. Med.
2005
11: 77-84
|
| 8327494 |
Lee JS et al.:
Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1.
Proc. Natl. Acad. Sci. U.S.A.
1993
90: 6145-6149
|
| 10809237 |
Lu S et al.:
Androgen induction of cyclin-dependent kinase inhibitor p21 gene: role of androgen receptor and transcription factor Sp1 complex.
Mol. Endocrinol.
2000
14: 753-760
|
| 12004059 |
Lee DK et al.:
POZ domain transcription factor, FBI-1, represses transcription of ADH5/FDH by interacting with the zinc finger and interfering with DNA binding activity of Sp1.
J. Biol. Chem.
2002
277
|
| 15878880 |
Lee JA et al.:
Transcriptional activity of Sp1 is regulated by molecular interactions between the zinc finger DNA binding domain and the inhibitory domain with corepressors, and this interaction is modulated by MEK.
J. Biol. Chem.
2005
280
|
| 10976766 |
Gunther M et al.:
A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening
Mol. Cell. Biochem.
2000
1-2: 131-142
|
| 10850422 |
Opitz OG et al.:
Interaction between Sp1 and cell cycle regulatory proteins is important in transactivation of a differentiation-related gene.
Cancer Res.
2000
60: 2825-2830
|
| 7933095 |
Sif S et al.:
Interaction of the v-Rel oncoprotein with cellular transcription factor Sp1.
J. Virol.
1994
68: 7131-7138
|
| 9153193 |
Armstrong SA et al.:
Casein kinase II-mediated phosphorylation of the C terminus of Sp1 decreases its DNA binding activity.
J. Biol. Chem.
1997
272
|
| 10547281 |
Rotheneder H et al.:
Transcription factors of the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter.
J. Mol. Biol.
1999
293: 1005-1015
|
| 21258409 |
Hwang-Verslues WW et al.:
miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1
Oncogene
2011
30: 2463-2474
|
| 10523830 |
Barbeau B et al.:
The GATA-1 and Spi-1 transcriptional factors bind to a GATA/EBS dual element in the Fli-1 exon 1.
Oncogene
1999
18: 5535-5545
|
| 8195185 |
Crossley M et al.:
Regulation of the erythroid Kruppel-like factor (EKLF) gene promoter by the erythroid transcription factor GATA-1.
J. Biol. Chem.
1994
269
|
| 20632962 |
White CM et al.:
Therapeutic potential of vasoactive intestinal peptide and its receptors in neurological disorders.
CNS Neurol Disord Drug Targets
2010
9: 661-666
|
| 18616823 |
Chaudhury D et al.:
Select cognitive deficits in vasoactive intestinal peptide deficient mice.
BMC Neurosci
2008
9: 63
|
| 17151217 |
Brown TM et al.:
Disrupted neuronal activity rhythms in the suprachiasmatic nuclei of vasoactive intestinal polypeptide-deficient mice.
J. Neurophysiol.
2007
97: 2553-2558
|
| 21540240 |
Tomita K et al.:
Disrupted-in-Schizophrenia-1 (Disc1) is necessary for migration of the pyramidal neurons during mouse hippocampal development.
Hum. Mol. Genet.
2011
20: 2834-2845
|
| 16051150 |
Beaulieu JM et al.:
An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior.
Cell
2005
122: 261-273
|
| 16672106 |
Li X et al.:
Regulation of mouse brain glycogen synthase kinase-3 by atypical antipsychotics.
Int. J. Neuropsychopharmacol.
2007
10: 7-19
|
| 15102436 |
Jope RS et al.:
The glamour and gloom of glycogen synthase kinase-3.
Trends Biochem. Sci.
2004
29: 95-102
|
| 21377444 |
Alves I et al.:
The interaction of antipsychotic drugs with lipids and subsequent lipid reorganization investigated using biophysical methods.
Biochim. Biophys. Acta
2011
1808: 2009-2018
|
| 15233746 |
Ansorge M et al.:
Analysis of the murine 5-HT receptor gene promoter in vitro and in vivo.
Eur. J. Neurosci.
2004
20: 363-374
|
| 18614564 |
McFarland MA et al.:
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions
Mol. Cell Proteomics
2008
7: 2123-2137
|
| 22384250 |
Shohat M et al.:
Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells
PLoS ONE
2012
7
|
| 16414345 |
Wang XM et al.:
The negative cell cycle regulator, Tob (transducer of ErbB-2), is involved in motor skill learning
Biochem. Biophys. Res. Commun.
2006
340: 1023-1027
|
| 22689267 |
Ohmura T et al.:
Neural tube defects by NUAK1 and NUAK2 double mutation
Dev. Dyn.
2012
241: 1350-1364
|
| 12628185 |
Cramer T et al.:
HIF-1alpha is essential for myeloid cell-mediated inflammation
Cell
2003
112: 645-657
|
| 15496141 |
Kuratomi G et al.:
NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor
Biochem. J.
2005
386: 461-470
|
| 16192303 |
Drummond HA et al.:
ENaC proteins are required for NGF-induced neurite growth
Am. J. Physiol.
2006
290: C404-C410
|
| 7539918 |
Wang GL et al.:
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
Proc. Natl. Acad. Sci. U.S.A.
1995
92: 5510-5514
|
| 11207939 |
Sun W et al.:
Evidence for direct involvement of beta-catenin in phorbol ester-induced neurite outgrowth in GT1-1 hypothalamic neurones
J. Neuroendocrinol.
2001
13: 249-260
|
| 10215617 |
Gutacker C et al.:
Nerve growth factor and epidermal growth factor stimulate clusterin gene expression in PC12 cells
Biochem. J.
1999
339: 759-766
|
| 17267689 |
Liu J et al.:
Nerve growth factor-mediated neurite outgrowth via regulation of Rab5
Mol. Biol. Cell
2007
18: 1375-1384
|
| 23223289 |
Spillane M et al.:
Nerve growth factor-induced formation of axonal filopodia and collateral branches involves the intra-axonal synthesis of regulators of the actin-nucleating Arp2/3 complex
J. Neurosci.
2012
32
|
| 9359840 |
Machesky LM et al.:
Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins
Biochem. J.
1997
328: ( Pt 1) 105-112
|
| 23554489 |
Kim IH et al.:
Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities
J. Neurosci.
2013
33: 6081-6092
|
| 11922865 |
Angelastro JM et al.:
Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins
BMC Neurosci
2002
3: 3
|
| 22792227 |
Porter NM et al.:
Hippocampal CA1 transcriptional profile of sleep deprivation: relation to aging and stress
PLoS ONE
2012
7
|
| 10679440 |
Wong WT et al.:
Rapid dendritic movements during synapse formation and rearrangement
Curr. Opin. Neurobiol.
2000
10: 118-124
|
| 23354722 |
Nacher J et al.:
Structural plasticity of interneurons in the adult brain: role of PSA-NCAM and implications for psychiatric disorders
Neurochem. Res.
2013
38: 1122-1133
|
| 15234189 |
Zhu HJ et al.:
Glutamate up-regulates P-glycoprotein expression in rat brain microvessel endothelial cells by an NMDA receptor-mediated mechanism
Life Sci.
2004
75: 1313-1322
|
| 16210420 |
Clark KA et al.:
Effects of central and systemic administration of leptin on neurotransmitter concentrations in specific areas of the hypothalamus
Am. J. Physiol. Regul. Integr. Comp. Physiol.
2006
290: R306-R312
|
| 16359813 |
Bortfeld M et al.:
Human multidrug resistance protein 8 (MRP8/ABCC11), an apical efflux pump for steroid sulfates, is an axonal protein of the CNS and peripheral nervous system
Neuroscience
2006
137: 1247-1257
|
| 19493957 |
Gartside SE et al.:
The neurosteroid dehydroepiandrosterone (DHEA) and its metabolites alter 5-HT neuronal activity via modulation of GABAA receptors
J. Psychopharmacol. (Oxford)
2010
24: 1717-1724
|
| 15537867 |
Chen ZS et al.:
Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11)
Mol. Pharmacol.
2005
67: 545-557
|
| 11898391 |
Jedlitschky G et al.:
Transport of leukotriene C4 and structurally related conjugates
Vitam. Horm.
2002
64: 153-184
|
| 21967058 |
Slot AJ et al.:
Mammalian multidrug-resistance proteins (MRPs)
Essays Biochem.
2011
50: 179-207
|
| 9815123 |
Blanco G et al.:
Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function
Am. J. Physiol.
1998
275: F633-F650
|
| 16449553 |
Beyenbach KW et al.:
The V-type H+ ATPase: molecular structure and function, physiological roles and regulation
J. Exp. Biol.
2006
209: 577-589
|
| 8250920 |
van Hille B et al.:
Cloning and tissue distribution of subunits C, D, and E of the human vacuolar H(+)-ATPase
Biochem. Biophys. Res. Commun.
1993
197: 15-21
|
| 12947086 |
Sun-Wada GH et al.:
Mouse proton pump ATPase C subunit isoforms (C2-a and C2-b) specifically expressed in kidney and lung
J. Biol. Chem.
2003
278
|
| 8883949 |
Baba-Aissa F et al.:
Purkinje neurons express the SERCA3 isoform of the organellar type Ca(2+)-transport ATPase
Brain Res. Mol. Brain Res.
1996
41: 169-174
|
| 15988472 |
Roy M et al.:
Genetic inactivation of melanin-concentrating hormone receptor subtype 1 (MCHR1) in mice exerts anxiolytic-like behavioral effects
Neuropsychopharmacology
2006
31: 112-120
|
| 21715637 |
Sherwood TW et al.:
Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death
J. Neurosci.
2011
31: 9723-9734
|
| 11031246 |
Catterall WA et al.:
Structure and regulation of voltage-gated Ca2+ channels
Annu. Rev. Cell Dev. Biol.
2000
16: 521-555
|
| 18799678 |
Bull R et al.:
Ischemia enhances activation by Ca2+ and redox modification of ryanodine receptor channels from rat brain cortex
J. Neurosci.
2008
28: 9463-9472
|
| 9275162 |
Zhang D et al.:
Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4
Proc. Natl. Acad. Sci. U.S.A.
1997
94: 9562-9567
|
| 12626632 |
Moresco EM et al.:
Abl family nonreceptor tyrosine kinases modulate short-term synaptic plasticity
J. Neurophysiol.
2003
89: 1678-1687
|
| 8929423 |
Liao YJ et al.:
Heteromultimerization of G-protein-gated inwardly rectifying K+ channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain
J. Neurosci.
1996
16: 7137-7150
|
| 23994450 |
Bruehl S et al.:
Associations between KCNJ6 (GIRK2) gene polymorphisms and pain-related phenotypes
Pain
2013
154: 2853-2859
|
| 10086340 |
Ettenberg SA et al.:
cbl-b inhibits epidermal growth factor receptor signaling
Oncogene
1999
18: 1855-1866
|
| 17541751 |
Ye JH et al.:
Regulation of excitation by glycine receptors
Results Probl Cell Differ
2008
44: 123-143
|
| 9738473 |
Occhiodoro T et al.:
Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion
FEBS Lett.
1998
434: 177-182
|
| 14612589 |
Hu S et al.:
Variants of the KCNMB3 regulatory subunit of maxi BK channels affect channel inactivation
Physiol. Genomics
2003
15: 191-198
|
| 12524525 |
Schwake M et al.:
A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly
EMBO Rep.
2003
4: 76-81
|
| 17474147 |
Wu C et al.:
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening
Proteomics
2007
7: 1775-1785
|
| 12160745 |
Honma Y et al.:
Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons
Neuron
2002
35: 267-282
|
| 15664173 |
Arlotta P et al.:
Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo
Neuron
2005
45: 207-221
|
| 11731465 |
Imondi R et al.:
Commissural axon pathfinding on the contralateral side of the floor plate: a role for B-class ephrins in specifying the dorsoventral position of longitudinally projecting commissural axons
Development
2001
128: 4859-4871
|
| 20369019 |
Nicolae DL et al.:
Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS
PLoS Genet.
2010
6
|
| 11085305 |
Yamagata K et al.:
Activation of an effector immediate-early gene arc by methamphetamine
Ann. N. Y. Acad. Sci.
2000
914: 22-32
|
| 10800951 |
Tan A et al.:
The activity-regulated cytoskeletal-associated protein arc is expressed in different striosome-matrix patterns following exposure to amphetamine and cocaine
J. Neurochem.
2000
74: 2074-2078
|
| 18430032 |
Bachtell RK et al.:
Role of GluR1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine-seeking behavior
Eur. J. Neurosci.
2008
27: 2229-2240
|
| 19524640 |
Schumann J et al.:
NR2A/B-containing NMDA receptors mediate cocaine-induced synaptic plasticity in the VTA and cocaine psychomotor sensitization
Neurosci. Lett.
2009
461: 159-162
|
| 21441996 |
Mao LM et al.:
Post-translational modification biology of glutamate receptors and drug addiction
Front Neuroanat
2011
5: 19
|
| 20720536 |
Anier K et al.:
DNA methylation regulates cocaine-induced behavioral sensitization in mice
Neuropsychopharmacology
2010
35: 2450-2461
|
| 24359476 |
Clarke TK et al.:
The dopamine receptor D2 (DRD2) SNP rs1076560 is associated with opioid addiction
Ann. Hum. Genet.
2014
78: 33-39
|
| 23670889 |
Carpenter CL et al.:
Association of dopamine D2 receptor and leptin receptor genes with clinically severe obesity
Obesity (Silver Spring)
2013
21: E467-E473
|
| 8261891 |
Noble EP et al.:
Allelic association of the D2 dopamine receptor gene with cocaine dependence
Drug Alcohol Depend
1993
33: 271-285
|
| 20112002 |
Sery O et al.:
A118G polymorphism of OPRM1 gene is associated with schizophrenia
J. Mol. Neurosci.
2010
41: 219-222
|
| 24078558 |
Jacobs M et al.:
HIV-related cognitive impairment shows bi-directional association with dopamine receptor DRD1 and DRD2 polymorphisms in substance-dependent and substance-independent populations
J. Neurovirol.
2013
19: 495-504
|
| 23635803 |
Spellicy CJ et al.:
ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse
Pharmacogenet. Genomics
2013
23: 333-340
|
| 21368124 |
Beutler LR et al.:
Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization
Proc. Natl. Acad. Sci. U.S.A.
2011
108: 4206-4211
|
| 23688924 |
Pol Bodetto S et al.:
Cocaine represses protein phosphatase-1Cbeta through DNA methylation and Methyl-CpG Binding Protein-2 recruitment in adult rat brain
Neuropharmacology
2013
73: 31-40
|
| 21338882 |
Chen JA et al.:
Mir-17-3p controls spinal neural progenitor patterning by regulating Olig2/Irx3 cross-repressive loop
Neuron
2011
69: 721-735
|
| 23940648 |
Zhao B et al.:
Analysis of variations in the glutamate receptor, N-methyl D-aspartate 2A (GRIN2A) gene reveals their relative importance as genetic susceptibility factors for heroin addiction
PLoS ONE
2013
8
|
| 23253944 |
Matosin N et al.:
Metabotropic glutamate receptor 5 in the pathology and treatment of schizophrenia
Neurosci Biobehav Rev
2013
37: 256-268
|
| 24594013 |
Xiang YY et al.:
Interaction of Acetylcholinesterase with Neurexin-1beta regulates Glutamatergic Synaptic stability in Hippocampal neurons
Mol Brain
2014
7: 15
|
| 24497299 |
Bourne Y et al.:
The Neuroligins and Their Ligands: from Structure to Function at the Synapse
|
| 21940442 |
Mondin M et al.:
Neurexin-neuroligin adhesions capture surface-diffusing AMPA receptors through PSD-95 scaffolds
J. Neurosci.
2011
31
|
| 11279200 |
Meddows E et al.:
Identification of molecular determinants that are important in the assembly of N-methyl-D-aspartate receptors
J. Biol. Chem.
2001
276
|
| 10480938 |
Hawkins LM et al.:
Biochemical evidence for the co-association of three N-methyl-D-aspartate (NMDA) R2 subunits in recombinant NMDA receptors
J. Biol. Chem.
1999
274
|
| 16281028 |
Furukawa H et al.:
Subunit arrangement and function in NMDA receptors
Nature
2005
438: 185-192
|
| 8768735 |
Hess SD et al.:
Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors
J. Pharmacol. Exp. Ther.
1996
278: 808-816
|
| 16467520 |
Li S et al.:
Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression
J. Neurosci.
2006
26: 1721-1729
|
| 14622581 |
Krapivinsky G et al.:
The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1
Neuron
2003
40: 775-784
|
| 15029245 |
Tian X et al.:
Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB
EMBO J.
2004
23: 1567-1575
|
| 8332187 |
Zhang XF et al.:
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
Nature
1993
364: 308-313
|
| 8940180 |
Alessandrini A et al.:
Mek1 phosphorylation site mutants activate Raf-1 in NIH 3T3 cells
J. Biol. Chem.
1996
271
|
| 22177953 |
Roskoski R Jr et al.:
MEK1/2 dual-specificity protein kinases: structure and regulation
Biochem. Biophys. Res. Commun.
2012
417: 5-10
|
| 22569528 |
Roskoski R Jr et al.:
ERK1/2 MAP kinases: structure, function, and regulation
Pharmacol. Res.
2012
66: 105-143
|
| 16172610 |
Dwivedi Y et al.:
ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf
Mol. Psychiatry
2006
11: 86-98
|
| 23986655 |
Chan WS et al.:
Differential regulation of proliferation and neuronal differentiation in adult rat spinal cord neural stem/progenitors by ERK1/2, Akt, and PLCgamma
Front Mol Neurosci
2013
6: 23
|
| 9808472 |
Impey S et al.:
Cross talk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation
Neuron
1998
21: 869-883
|
| 11306573 |
Kasahara J et al.:
Activation of calcium/calmodulin-dependent protein kinase IV in long term potentiation in the rat hippocampal CA1 region
J. Biol. Chem.
2001
276
|
| 9892651 |
Tezuka T et al.:
PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A
Proc. Natl. Acad. Sci. U.S.A.
1999
96: 435-440
|
| 8245028 |
Lee SB et al.:
Activation of phospholipase C-beta 2 mutants by G protein alpha q and beta gamma subunits
J. Biol. Chem.
1993
268
|
| 16919684 |
Reymann KG et al.:
The late maintenance of hippocampal LTP: requirements, phases, synaptic tagging, late-associativity and implications
Neuropharmacology
2007
52: 24-40
|
| 11158244 |
Grosshans DR et al.:
Protein kinase C activation induces tyrosine phosphorylation of the NR2A and NR2B subunits of the NMDA receptor
J. Neurochem.
2001
76: 737-744
|
| 20055706 |
Niswender CM et al.:
Metabotropic glutamate receptors: physiology, pharmacology, and disease
Annu. Rev. Pharmacol. Toxicol.
2010
50: 295-322
|
| 24758191 |
Fujioka R et al.:
Comprehensive behavioral study of mGluR3 knockout mice: implication in schizophrenia related endophenotypes
Mol Brain
2014
7: 31
|
| 18691652 |
Gierke P et al.:
Implication of neuronal Ca2+ -sensor protein VILIP-1 in the glutamate hypothesis of schizophrenia
Neurobiol. Dis.
2008
32: 162-175
|
| 1892543 |
Tsagarakis S et al.:
Involvement of calmodulin in depolarization-induced release of corticotrophin-releasing hormone-41 from the rat hypothalamus in vitro
J. Mol. Endocrinol.
1991
7: 71-75
|
| 14722323 |
Marrero MB et al.:
The neuroprotective effect of 2-(3-pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698), a novel alpha7 ligand, is prevented through angiotensin II activation of a tyrosine phosphatase
J. Pharmacol. Exp. Ther.
2004
309: 16-27
|
| 19304867 |
Singh RK et al.:
Activation of the JAK-STAT pathway by olanzapine is necessary for desensitization of serotonin2A receptor-stimulated phospholipase C signaling in rat frontal cortex but not serotonin2A receptor-stimulated hormone release
J. Psychopharmacol. (Oxford)
2010
24: 1079-1088
|
| 10521509 |
Posner BA et al.:
Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways
J. Biol. Chem.
1999
274
|
| 15750602 |
Maltez JM et al.:
Essential Ca(V)beta modulatory properties are AID-independent
Nat. Struct. Mol. Biol.
2005
12: 372-377
|
| 17409629 |
Kobayashi T et al.:
Regulation of Cav1.2 current: interaction with intracellular molecules
J. Pharmacol. Sci.
2007
103: 347-353
|
| 1689727 |
Boulter J et al.:
Alpha 3, alpha 5, and beta 4: three members of the rat neuronal nicotinic acetylcholine receptor-related gene family form a gene cluster
J. Biol. Chem.
1990
265: 4472-4482
|
| 9655874 |
Gerzanich V et al.:
alpha 5 Subunit alters desensitization, pharmacology, Ca++ permeability and Ca++ modulation of human neuronal alpha 3 nicotinic receptors
J. Pharmacol. Exp. Ther.
1998
286: 311-320
|
| 3998824 |
author information missing
Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin
J. Neurosci.
1985
5: 1307-1315
|
| 24297903 |
Andersen N et al.:
Stoichiometry for activation of neuronal alpha7 nicotinic receptors
Proc. Natl. Acad. Sci. U.S.A.
2013
110
|
| 21203548 |
Espeseth T et al.:
Nicotinic receptor gene CHRNA4 interacts with processing load in attention
PLoS ONE
2010
5
|
| 22716019 |
Tavares Xda S et al.:
Variations in binding among several agonists at two stoichiometries of the neuronal, alpha4beta2 nicotinic receptor
J. Am. Chem. Soc.
2012
134
|
| 21145461 |
Bennett EJ et al.:
Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics
Cell
2010
143: 951-965
|
| 23055483 |
Earls LR et al.:
Age-dependent microRNA control of synaptic plasticity in 22q11 deletion syndrome and schizophrenia
J. Neurosci.
2012
32
|
| 15147903 |
Carrasco-Serrano C et al.:
Glucocorticoid activation of the neuronal nicotinic acetylcholine receptor alpha7 subunit gene: involvement of transcription factor Egr-1
FEBS Lett.
2004
566: 247-250
|
| 21169352 |
Li C et al.:
Structural analysis of Mg2+ and Ca2+ binding, myristoylation, and dimerization of the neuronal calcium sensor and visinin-like protein 1 (VILIP-1)
J. Biol. Chem.
2011
286: 6354-6366
|
| 21665950 |
Minano-Molina AJ et al.:
Soluble oligomers of amyloid-beta peptide disrupt membrane trafficking of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor contributing to early synapse dysfunction
J. Biol. Chem.
2011
286
|
| 23569253 |
Veyrac A et al.:
Zif268/egr1 gene controls the selection, maturation and functional integration of adult hippocampal newborn neurons by learning
Proc. Natl. Acad. Sci. U.S.A.
2013
110: 7062-7067
|
| 3760271 |
author information missing
Treatment of basal cell carcinoma with intralesional interferon
J. Am. Acad. Dermatol.
1986
15: 437-443
|
| 15456862 |
May P et al.:
Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice
Mol. Cell. Biol.
2004
24: 8872-8883
|
| 25042179 |
Li X et al.:
D-Serine-induced Inactivation of NMDA Receptors in Cultured Rat Hippocampal Neurons Expressing NR2A Subunits is Ca -Dependent
|
| 11054547 |
De Miranda J et al.:
Human serine racemase: moleular cloning, genomic organization and functional analysis
Gene
2000
256: 183-188
|
| 24915645 |
Balu DT et al.:
Chronic D-serine reverses arc expression and partially rescues dendritic abnormalities in a mouse model of NMDA receptor hypofunction
Neurochem. Int.
2014
75: 76-78
|
| 18199763 |
Arlotta P et al.:
Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum
J. Neurosci.
2008
28: 622-632
|
| 24904288 |
Guzman RE et al.:
Involvement of ClC-3 chloride/proton exchangers in controlling glutamatergic synaptic strength in cultured hippocampal neurons
Front Cell Neurosci
2014
8: 143
|
| 12470859 |
Dickerson LW et al.:
Altered GABAergic function accompanies hippocampal degeneration in mice lacking ClC-3 voltage-gated chloride channels
Brain Res.
2002
958: 227-250
|
| 9197267 |
Barria A et al.:
Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation
Science
1997
276: 2042-2045
|
| 17046694 |
Wang XQ et al.:
CLC-3 channels modulate excitatory synaptic transmission in hippocampal neurons
Neuron
2006
52: 321-333
|
| 15225550 |
Yu J et al.:
Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses
Mol. Cell
2004
15: 83-94
|
| 11050151 |
Sun Y et al.:
Regulation of beta -catenin transformation by the p300 transcriptional coactivator
Proc. Natl. Acad. Sci. U.S.A.
2000
97
|
| 9001254 |
Sartorelli V et al.:
Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C
Mol. Cell. Biol.
1997
17: 1010-1026
|
| 8918891 |
Giandomenico V et al.:
Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors
Mol. Cell. Biol.
2003
23: 2587-2599
|
| 10373589 |
Gingras S et al.:
p300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6
Nucleic Acids Res.
1999
27: 2722-2729
|
| 8848048 |
Bhattacharya S et al.:
Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha
Nature
1996
383: 344-347
|
| 16217014 |
Thomas GM et al.:
Ribosomal S6 kinase 2 interacts with and phosphorylates PDZ domain-containing proteins and regulates AMPA receptor transmission
Proc. Natl. Acad. Sci. U.S.A.
2005
102
|
| 18156174 |
Kang S et al.:
Epidermal growth factor stimulates RSK2 activation through activation of the MEK/ERK pathway and src-dependent tyrosine phosphorylation of RSK2 at Tyr-529
J. Biol. Chem.
2008
283: 4652-4657
|
| 21268077 |
Tung WH et al.:
Enterovirus 71 modulates a COX-2/PGE2/cAMP-dependent viral replication in human neuroblastoma cells: role of the c-Src/EGFR/p42/p44 MAPK/CREB signaling pathway
J. Cell. Biochem.
2011
112: 559-570
|
| 24796865 |
Goodell DJ et al.:
CaMKII binding to GluN2B is differentially affected by macromolecular crowding reagents
PLoS ONE
2014
9
|
| 23414621 |
Saito M et al.:
MAOA/B deletion syndrome in male siblings with severe developmental delay and sudden loss of muscle tonus
Brain Dev.
2014
36: 64-69
|
| 25612291 |
Prados J et al.:
Borderline personality disorder and childhood maltreatment: a genome-wide methylation analysis
Genes Brain Behav.
2015
14: 177-188
|
| 10809672 |
Constam DB et al.:
SPC4/PACE4 regulates a TGFbeta signaling network during axis formation
Genes Dev.
2000
14: 1146-1155
|
| 21051773 |
Scerri TS et al.:
PCSK6 is associated with handedness in individuals with dyslexia
Hum Mol Genet
2011
20: 608-614
|
| 10734093 |
Grimes JA et al.:
The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex
J. Biol. Chem.
2000
275: 9461-9467
|
| 12032298 |
Hakimi MA et al.:
A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes
Proc. Natl. Acad. Sci. U.S.A.
2002
99: 7420-7425
|
| 16079794 |
Lee MG et al.:
An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation
Nature
2005
437: 432-435
|
| 10569182 |
Yamaguchi M et al.:
Expression of calcium-binding protein regucalcin and microsomal Ca2+-ATPase regulation in rat brain: attenuation with increasing age
Mol. Cell. Biochem.
1999
200: 43-49
|
| 10567674 |
Hanahisa Y et al.:
Brain microsomal calcium accumulation in rats with increasing age: involvement of thapsigargin-sensitive Ca2+-ATPase
Int. J. Mol. Med.
1999
4: 627-631
|
| 18181158 |
Yamaguchi M et al.:
Regucalcin increases Ca2+-ATPase activity in the mitochondria of brain tissues of normal and transgenic rats
J. Cell. Biochem.
2008
104: 795-804
|
| 24917504 |
Aguiar DP et al.:
The facial neural crest controls fore- and midbrain patterning by regulating Foxg1 expression through Smad1 activity
Development
2014
141: 2494-2505
|
| 22998673 |
Guerrini R et al.:
Epilepsy in Rett syndrome, and CDKL5- and FOXG1-gene-related encephalopathies
Epilepsia
2012
53: 2067-2078
|
| 22354967 |
Kumamoto T et al.:
Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression
Cell Rep
2013
3: 931-945
|
| 23792689 |
Li H et al.:
A Bcl-xL-Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis
Nat. Cell Biol.
2013
15: 773-785
|
| 9693107 |
Sagane K et al.:
Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain
Biochem. J.
1998
334: 93-98
|
| 12088751 |
Rybnikova E et al.:
Developmental regulation and neuronal expression of the cellular disintegrin ADAM11 gene in mouse nervous system
Neuroscience
2002
112: 921-934
|
| 16504143 |
Takahashi E et al.:
Deficits in spatial learning and motor coordination in ADAM11-deficient mice
BMC Neurosci
2006
7: 19
|
| 20018883 |
Weaver MS et al.:
Processing of the matricellular protein hevin in mouse brain is dependent on ADAMTS4
J. Biol. Chem.
2010
285: 5868-5877
|
| 18178186 |
Hamel MG et al.:
Multimodal signaling by the ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) promotes neurite extension
Exp. Neurol.
2008
210: 428-440
|
| 25622912 |
Gottschall PE et al.:
ADAMTS expression and function in central nervous system injury and disorders
Matrix Biol.
2015
44-46C: 70-76
|
| 25104607 |
Han D et al.:
Global transcriptome profiling of genes that are differentially regulated during differentiation of mouse embryonic neural stem cells into astrocytes
J. Mol. Neurosci.
2015
55: 109-125
|
| 22457503 |
Mouri A et al.:
MAGE-D1 regulates expression of depression-like behavior through serotonin transporter ubiquitylation
J. Neurosci.
2012
32: 4562-4580
|
| 23576431 |
Sun T et al.:
c-Jun NH2-terminal kinase (JNK)-interacting protein-3 (JIP3) regulates neuronal axon elongation in a kinesin- and JNK-dependent manner
J. Biol. Chem.
2013
288
|
| 21775604 |
Huang SH et al.:
JIP3 mediates TrkB axonal anterograde transport and enhances BDNF signaling by directly bridging TrkB with kinesin-1
J. Neurosci.
2011
31
|
| 24700102 |
Yang J et al.:
Maged1 co-interacting with CREB through a hexapeptide repeat domain regulates learning and memory in mice
Mol. Neurobiol.
2015
51: 8-18
|
| 15356203 |
Rhodes KJ et al.:
KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain
J. Neurosci.
2004
36: 7903-7915
|
| 20943905 |
Norris AJ et al.:
Interdependent roles for accessory KChIP2, KChIP3, and KChIP4 subunits in the generation of Kv4-encoded IA channels in cortical pyramidal neurons
J. Neurosci.
2010
41
|
| 11008217 |
Gobron S et al.:
Subcommissural organ/Reissners fiber complex: characterization of SCO-spondin, a glycoprotein with potent activity on neurite outgrowth
Glia
2000
32: 177-191
|
| 22360420 |
Martins-de-Souza D et al.:
Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration
J. Proteome Res.
2012
11: 2533-2543
|
| 23761733 |
Vera A et al.:
SCO-spondin from embryonic cerebrospinal fluid is required for neurogenesis during early brain development
Front Cell Neurosci
2013
7: 80
|
| 21273429 |
Rubio MD et al.:
Regulation of synapse structure and function by distinct myosin II motors
J. Neurosci.
2011
31: 1448-1460
|
| 26286357 |
Eisenberger T et al.:
Targeted and genomewide NGS data disqualify mutations in MYO1A, the DFNA48 gene, as a cause of deafness
Hum. Mutat.
2014
35: 565-570
|
| 15023537 |
Mutoh T et al.:
Cadherin-related neuronal receptor 1 (CNR1) has cell adhesion activity with beta1 integrin mediated through the RGD site of CNR1
Exp. Cell Res.
2004
294: 494-508
|
| 17403907 |
Bonn S et al.:
Combinatorial expression of alpha- and gamma-protocadherins alters their presenilin-dependent processing
Mol. Cell. Biol.
2007
27: 4121-4132
|
| 20730872 |
Stanic K et al.:
Subdivisions of chick diencephalic roof plate: implication in the formation of the posterior commissure
Dev. Dyn.
2010
239: 2584-2593
|
| 10380929 |
Wu Q et al.:
A striking organization of a large family of human neural cadherin-like cell adhesion genes
Cell
1999
97: 779-790
|
| 9655502 |
Kohmura N et al.:
Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex
Neuron
1998
20: 1137-1151
|
| 25446008 |
Garafola CS et al.:
A change in hippocampal protocadherin gamma expression in a learned helpless rat
Brain Res.
2014
1593: 55-64
|
| 23783460 |
Vandewalle J et al. et al.:
The mitochondrial solute carrier SLC25A5 at Xq24 is a novel candidate gene for non-syndromic intellectual disability
Hum. Genet.
2013
132: 1177-1185
|
| 17236127 |
Laumonnier F et al.:
The role of neuronal complexes in human X-linked brain diseases
Am. J. Hum. Genet.
2007
80: 205-220
|
| 10729226 |
Amler LC et al.:
Identification and characterization of novel genes located at the t(1;15)(p36.2;q24) translocation breakpoint in the neuroblastoma cell line NGP
Genomics
2000
64: 195-202
|
| 12417639 |
Shimokawa N et al.:
Past-A, a novel proton-associated sugar transporter, regulates glucose homeostasis in the brain
J. Neurosci.
2002
22: 9160-9165
|
| 15763422 |
Munir S et al.:
Association analysis of GWAS and candidate gene loci in a Pakistani population with psoriasis
Mol. Immunol.
2015
64: 190-194
|
| 22046233 |
Reitz C et al.:
Impact of genetic variation in SORCS1 on memory retention
PLoS ONE
2011
6
|
| 12482870 |
Hermey G et al.:
Characterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cells
J. Biol. Chem.
2003
278: 7390-7396
|
| 10600506 |
Hermey G et al.:
Identification and characterization of SorCS, a third member of a novel receptor family
Biochem. Biophys. Res. Commun.
1999
266: 347-351
|
| 11165493 |
Rezgaoui M et al.:
Identification of SorCS2, a novel member of the VPS10 domain containing receptor family, prominently expressed in the developing mouse brain
Mech. Dev.
2001
100: 335-338
|
| 15009648 |
Hermey G et al.:
The three sorCS genes are differentially expressed and regulated by synaptic activity
J. Neurochem.
2004
88: 1470-1476
|
| 26291160 |
Savas JN et al. et al.:
The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors
Neuron
2015
87: 764-780
|
| 19434368 |
Hermey G et al.:
The Vps10p-domain receptor family
Cell. Mol. Life Sci.
2009
66: 2677-2689
|
| 23071613 |
Bayes A et al.:
Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins
PLoS ONE
2012
7
|
| 11251078 |
Baillat G et al.:
Molecular cloning and characterization of phocein, a protein found from the Golgi complex to dendritic spines
Mol. Biol. Cell
2001
12: 663-673
|
| 10681496 |
Moreno CS et al.:
WD40 repeat proteins striatin and S/G(2) nuclear autoantigen are members of a novel family of calmodulin-binding proteins that associate with protein phosphatase 2A
J. Biol. Chem.
2000
275: 5257-5263
|
| 8769426 |
Castets F et al.:
A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons
J. Cell Biol.
1996
134: 1051-1062
|
| 23055476 |
Lane RF et al.:
Vps10 family proteins and the retromer complex in aging-related neurodegeneration and diabetes
J. Neurosci.
2012
32
|
| 11707266 |
Gaillard S et al.:
Striatin, a calmodulin-dependent scaffolding protein, directly binds caveolin-1
FEBS Lett.
2001
508: 49-52
|
| 16445688 |
Gaillard S et al.:
Targeting of proteins of the striatin family to dendritic spines: role of the coiled-coil domain
Traffic
2006
7: 74-84
|
| 16460920 |
Benoist M et al.:
The striatin family: a new signaling platform in dendritic spines
J. Physiol. Paris
2006
99: 146-153
|
| 10413453 |
Bartoli M et al.:
Down-regulation of striatin, a neuronal calmodulin-binding protein, impairs rat locomotor activity
J. Neurobiol.
1999
40: 234-243
|
| 18782753 |
author information missing
article information missing
|
| 23015759 |
Chen YK et al.:
CTTNBP2, but not CTTNBP2NL, regulates dendritic spinogenesis and synaptic distribution of the striatin-PP2A complex
Mol. Biol. Cell
2012
23: 4383-4392
|
| 22865874 |
Dombret C et al.:
Loss of Maged1 results in obesity, deficits of social interactions, impaired sexual behavior and severe alteration of mature oxytocin production in the hypothalamus
Hum. Mol. Genet.
2012
21: 4703-4717
|
| 21228151 |
Dastidar SG et al.:
FoxG1 promotes the survival of postmitotic neurons
J. Neurosci.
2011
31: 402-413
|
| 24068947 |
Brandler WM et al.:
Common variants in left/right asymmetry genes and pathways are associated with relative hand skill
PLoS Genet.
2013
9
|
| 26186194 |
Huttlin EL et al.:
The BioPlex Network: A Systematic Exploration of the Human Interactome
Cell
2015
162: 425-440
|
| 25332075 |
Reitz C et al.:
The role of the retromer complex in aging-related neurodegeneration: a molecular and genomic review
Mol. Genet. Genomics
2015
290: 413-427
|
| 22171029 |
Benito E et al.:
cAMP response element-binding protein is a primary hub of activity-driven neuronal gene expression
J. Neurosci.
2011
31
|
| 18815592 |
Lin Y et al.:
Activity-dependent regulation of inhibitory synapse development by Npas4
Nature
2008
455: 1198-1204
|
| 23029555 |
Coutellier L et al.:
Npas4: a neuronal transcription factor with a key role in social and cognitive functions relevant to developmental disorders
PLoS ONE
2012
7
|
| 23924600 |
Toker L et al.:
Inositol-related gene knockouts mimic lithiums effect on mitochondrial function
Neuropsychopharmacology
2014
39: 319-328
|
| 6269180 |
author information missing
Lithium increases serotonin release and decreases serotonin receptors in the hippocampus
Science
1981
213: 1529-1531
|
| 1646857 |
Bennett GS et al.:
Lithium chloride inhibits the phosphorylation of newly synthesized neurofilament protein, NF-M, in cultured chick sensory neurons
J. Neurochem.
1991
57: 120-129
|
| 4030895 |
author information missing
Lithium ion inhibits nerve growth factor-induced neurite outgrowth and phosphorylation of nerve growth factor-modulated microtubule-associated proteins
J. Cell Biol.
1985
101: 862-870
|
| 10578449 |
Manji HK et al.:
Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness
Biol. Psychiatry
1999
46: 1328-1351
|
| 6439191 |
author information missing
The interaction of lithium with thyrotropin-releasing hormone-stimulated lipid metabolism in GH3 pituitary tumour cells. Enhancement of stimulated 1,2-diacylglycerol formation
Biochem. J.
1984
224: 129-136
|
| 9685653 |
Yuan PX et al.:
Lithium stimulates gene expression through the AP-1 transcription factor pathway
Brain Res. Mol. Brain Res.
1998
58: 225-230
|
| 9523597 |
Chen G et al.:
Lithium increases tyrosine hydroxylase levels both in vivo and in vitro
J. Neurochem.
1998
70: 1768-1771
|
| 1718537 |
Weiner ED et al.:
Lithium augments pilocarpine-induced fos gene expression in rat brain
Brain Res.
1991
553: 117-122
|
| 10582587 |
Yuan P et al.:
Lithium activates the c-Jun NH2-terminal kinases in vitro and in the CNS in vivo
J. Neurochem.
1999
73: 2299-2309
|
| 7722518 |
Nestler EJ et al.:
Regulation of endogenous ADP-ribosylation by acute and chronic lithium in rat brain
J. Neurochem.
1995
64: 2319-2324
|
| 24639496 |
Farhy Tselnicker I et al.:
Dual regulation of G proteins and the G-protein-activated K+ channels by lithium
Proc. Natl. Acad. Sci. U.S.A.
2014
111: 5018-5023
|
| 3340189 |
Avissar S et al.:
Lithium inhibits adrenergic and cholinergic increases in GTP binding in rat cortex
Nature
1988
331: 440-442
|
| 17950380 |
Yanagita T et al.:
Lithium inhibits function of voltage-dependent sodium channels and catecholamine secretion independent of glycogen synthase kinase-3 in adrenal chromaffin cells
Neuropharmacology
2007
7: 881-889
|
| 15456937 |
Kirshenboim N et al.:
Lithium-mediated phosphorylation of glycogen synthase kinase-3beta involves PI3 kinase-dependent activation of protein kinase C-alpha
J. Mol. Neurosci.
2004
24: 237-245
|
| 10411946 |
Chalecka-Franaszek E et al.:
Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons
Proc. Natl. Acad. Sci. U.S.A.
1999
96: 8745-8750
|
| 18077182 |
Liang MH et al.:
Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling
Mol. Cell. Neurosci.
2008
37: 440-453
|
| 11897496 |
Mora A et al.:
Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A
Cell. Signal.
2002
14: 557-562
|
| 21821916 |
O'Brien WT et al.:
Glycogen synthase kinase-3 is essential for beta-arrestin-2 complex formation and lithium-sensitive behaviors in mice
J. Clin. Invest.
2011
121: 3756-3762
|
| 12090811 |
Rapoport SI et al.:
Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder? }, authors { names std { { name ml Rapoport SI, affil str Brain Physiology and Metabolism Section, Bldg 10, Room 6N202, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA. sir@helix.nih.gov }, { name ml Bosetti F } } }, from journal { title { iso-jta Arch. Gen. Psychiatry, ml-jta Arch Gen Psychiatry, issn 0003-990X, name Archives of general psychiatry }, imp { date std { year 2002, month 7 }, volume 59, issue 7, pages 592-596, language eng, pubstatus ppublish, history { { pubstatus pubmed, date std { year 2002, month 7, day 2, hour 10, minute 0 } }, { pubstatus medline, date std { year 2002, month 8, day 7, hour 10, minute 1 } }, { pubstatus other, date std { year 2002, month 7, day 2, hour 10, minute 0 } } } } }, ids { pubmed 12090811, pii ynv10318 } }, abstract BACKGROUND: Lithium and certain anticonvulsants, including carbamazepine and valproic acid, are effective antimanic drugs for treating bipolar disorder, but their mechanisms of action remain uncertain. EXPERIMENTAL OBSERVATIONS: Feeding rats lithium chloride for 6 weeks, to produce a brain lithium concentration of 0.7mM, reduced arachidonic acid turnover within brain phospholipids by 75%. The effect was highly specific, as turnover rates of docosahexaenoic acid and palmitic acid were unaffected. Arachidonate turnover in rat brain also was reduced by long-term valproic acid administration. Lithiums reduction of arachidonate turnover corresponded to its down-regulating gene expression and enzyme activity of cytosolic phospholipase A(2), an enzyme that selectively liberates arachidonic but not docosahexaenoic acid from phospholipids. Lithium also reduced the brain protein level and activity of cyclooxygenase 2, as well as the brain concentration of prostaglandin E(2), an arachidonate metabolite produced via cyclooxygenase 2. CONCLUSIONS: These results give rise to the hypothesis that lithium and antimanic anticonvulsants act by targeting parts of the arachidonic acid cascade, which may be functionally hyperactive in mania. Thus, drugs that target enzymes in the cascade, such as cyclooxygenase 2 inhibitors, might be candidate treatments for mania. Also, in view of competition between arachidonic and docosahexaenoic acids in a number of functional processes, docosahexaenoic acid or its precursors would be expected to be therapeutic. Neither of these predictions is evident from other current hypotheses for the antimanic action of lithium and anticonvulsant drugs
Arch. Gen. Psychiatry
2002
59: 592-596
|
| 8867516 |
Berk M et al.:
Lithium blocks 45Ca2+ uptake into platelets in bipolar affective disorder and controls
Clin Neuropharmacol
1996
19: 48-51
|
| 1720545 |
Colin SF et al.:
Chronic lithium regulates the expression of adenylate cyclase and Gi-protein alpha subunit in rat cerebral cortex
Proc. Natl. Acad. Sci. U.S.A.
1991
88
|
| 8245981 |
Manji HK et al.:
Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme
J. Neurochem.
1993
61: 2303-2310
|
| 11689187 |
Miki M et al.:
Effects of subchronic lithium chloride treatment on G-protein subunits (Golf, Ggamma7) and adenylyl cyclase expressed specifically in the rat striatum
Eur. J. Pharmacol.
2001
428: 303-309
|
| 8970502 |
Lenox RH et al.:
Myristoylated alanine-rich C kinase substrate (MARCKS): a molecular target for the therapeutic action of mood stabilizers in the brain? }, authors { names std { { name ml Lenox RH, affil str Department of Psychiatry, University of Florida, University of Florida College of Medicine, Gainesville, USA
J Clin Psychiatry
1996
57: 23-31
|
| 11841566 |
Hashimoto R et al.:
Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation
J. Neurochem.
2002
80: 589-597
|
| 26171981 |
Lee RS et al.:
Search for common targets of lithium and valproic acid identifies novel epigenetic effects of lithium on the rat leptin receptor gene
Transl Psychiatry
2015
5: E600
|
| 15024025 |
Leonoudakis D et al.:
Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins
J. Biol. Chem.
2004
279
|
| 10681520 |
Kiyono M et al.:
Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) following phosphorylation by the nonreceptor tyrosine kinase Src
J. Biol. Chem.
2000
275: 5441-5446
|
| 25644714 |
DiBattista AM et al.:
Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner
Biochim. Biophys. Acta
2015
1853: 904-917
|
| 21111786 |
Fernandez-Medarde A et al.:
The RasGrf family of mammalian guanine nucleotide exchange factors
Biochim. Biophys. Acta
2011
1815: 170-188
|
| 10488080 |
Christopherson KS et al.:
PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain
J. Biol. Chem.
1999
274
|
| 18367167 |
Gardoni F et al.:
MAGUK proteins: new targets for pharmacological intervention in the glutamatergic synapse
Eur. J. Pharmacol.
2008
585: 147-152
|
| 24755227 |
Jin SX et al.:
Domain contributions to signaling specificity differences between Ras-guanine nucleotide releasing factor (Ras-GRF) 1 and Ras-GRF2
J. Biol. Chem.
2014
289
|
| 26997484 |
et al.:
|
| 19812333 |
Wang X et al.:
A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1
J. Neurosci.
2009
29
|
| 9679147 |
tom Dieck S et al.:
Bassoon, a novel zinc-finger CAG/glutamine-repeat protein selectively localized at the active zone of presynaptic nerve terminals
J. Cell Biol.
1998
142: 499-509
|
| 26793095 |
Gundelfinger ED et al.:
Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone
Front Synaptic Neurosci
2016
7: 19
|
| 27907191 |
Terry-Lorenzo RT et al.:
Trio, a Rho Family GEF, Interacts with the Presynaptic Active Zone Proteins Piccolo and Bassoon
PLoS ONE
2016
11
|
| 15340156 |
Shi SH et al.:
The immunoglobulin family member dendrite arborization and synapse maturation 1 (Dasm1) controls excitatory synapse maturation
Proc. Natl. Acad. Sci. U.S.A.
2004
101
|
| 24647940 |
Mishra A et al.:
Genetic evidence for the adhesion protein IgSF9/Dasm1 to regulate inhibitory synapse development independent of its intracellular domain
J. Neurosci.
2014
12: 4187-4199
|
| 8999968 |
Betz A et al.:
Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin
J Biol Chem
1997
272: 2520-2526
|
| 23417431 |
Hansen M et al.:
IGSF9 family proteins
Neurochem. Res.
2013
6: 1236-1251
|
| 21228161 |
Chen J et al.:
Calcium channels link the muscle-derived synapse organizer laminin beta2 to Bassoon and CAST/Erc2 to organize presynaptic active zones
J. Neurosci.
2011
31: 512-525
|
| 27778639 |
Arnold AC et al.:
Hyperinsulinemia and Insulin Resistance in Dopamine beta-Hydroxylase Deficiency
J. Clin. Endocrinol. Metab.
2017
102: 10-14
|
| 21677356 |
Walczewska A et al.:
[The role of docosahexaenoic acid in neuronal function]
Postepy Hig Med Dosw (Online)
2011
65: 314-327
|
| 10954708 |
Perrier AL et al.:
Two distinct proteins are associated with tetrameric acetylcholinesterase on the cell surface
J. Biol. Chem.
2000
275
|
| 25557959 |
Hou P et al.:
Role of copper and the copper-related protein CUTA in mediating APP processing and Abeta generation
Neurobiol. Aging
2015
36: 1310-1315
|
| 17961154 |
Spilker C et al.:
SPAR2, a novel SPAR-related protein with GAP activity for Rap1 and Rap2
J. Neurochem.
2008
104: 187-201
|
| 17720279 |
Chiba T et al.:
Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: implications for longevity
Neurobiol. Aging
2009
3: 474-482
|
| 17720279 |
Chiba T et al.:
Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: implications for longevity
Neurobiol. Aging
2009
30: 474-482
|
| 22767515 |
Crespi A et al.:
LIN7 regulates the filopodium- and neurite-promoting activity of IRSp53
J. Cell. Sci.
2012
125: 4543-4554
|
| 22328498 |
Endo M et al.:
Ror family receptor tyrosine kinases regulate the maintenance of neural progenitor cells in the developing neocortex
J. Cell. Sci.
2012
125: 2017-2029
|
| 26918762 |
Forsova OS et al.:
High-order oligomers of intrinsically disordered brain proteins BASP1 and GAP-43 preserve the structural disorder
FEBS J.
2016
283: 1550-1569
|
| 7931336 |
Svennerholm L et al.:
Membrane lipids of adult human brain: lipid composition of frontal and temporal lobe in subjects of age 20 to 100 years
J. Neurochem.
1994
63: 1802-1811
|
| 26497036 |
Castex MT et al.:
Selenoprotein T Deficiency Leads to Neurodevelopmental Abnormalities and Hyperactive Behavior in Mice
Mol. Neurobiol.
2016
53: 5818-5832
|
| 20920667 |
Agamy O et al.:
Mutations disrupting selenocysteine formation cause progressive cerebello-cerebral atrophy
Am. J. Hum. Genet.
2010
87: 538-544
|
| 18350150 |
Soerensen J et al.:
The role of thioredoxin reductases in brain development
PLoS ONE
2008
3: e1813
|
| 28579431 |
Wang C et al.:
Direct interaction between selenoprotein R and Abeta42
Biochem. Biophys. Res. Commun.
2017
489: 509-514
|
| 20521393 |
Takemoto AS et al.:
Role of selenoprotein P in Alzheimers disease
Ethn Dis
2010
20: S1-92-5
|
| 27802219 |
Rueli RH et al.:
Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology
J. Alzheimers Dis.
2017
55: 749-762
|
| 26866473 |
Boukhzar L et al.:
Selenoprotein T Exerts an Essential Oxidoreductase Activity That Protects Dopaminergic Neurons in Mouse Models of Parkinsons Disease
Antioxid. Redox Signal.
2016
24: 557-574
|
| 25201965 |
Wang S et al.:
Phosphatidylethanolamine deficiency disrupts alpha-synuclein homeostasis in yeast and worm models of Parkinson disease
Proc. Natl. Acad. Sci. U.S.A.
2014
111
|
| 29500230 |
Grumolato L et al.:
Selenoprotein T is a PACAP-regulated gene involved in intracellular Ca2+ mobilization and neuroendocrine secretion
FASEB J.
2008
22: 1756-1768
|
| 25996565 |
Cardoso BR et al.:
Selenium, selenoproteins and neurodegenerative diseases
Metallomics
2015
7: 1213-1228
|
| 23226354 |
Lopert P et al.:
Thioredoxin reductase deficiency potentiates oxidative stress, mitochondrial dysfunction and cell death in dopaminergic cells
PLoS ONE
2012
7
|
| 25269742 |
Kim Y et al.:
Identification of the responsible proteins for increased selenium bioavailability in the brain of transgenic rats overexpressing selenoprotein M
Int. J. Mol. Med.
2014
34: 1688-1698
|
| 24152552 |
author information missing
Genome-wide identification of mRNAs associated with the protein SMN whose depletion decreases their axonal localization
RNA
2013
19: 1755-1766
|
| 29286308 |
Fredericks GJ et al.:
Selenoprotein K Increases Efficiency of DHHC6 Catalyzed Protein Palmitoylation by Stabilizing the Acyl-DHHC6 Intermediate
|
| 11086297 |
Rasband MN et al.:
Subunit composition and novel localization of K+ channels in spinal cord
J. Comp. Neurol.
2001
429: 166-176
|
| 8789960 |
Sewing S et al.:
Kv beta 1 subunit binding specific for shaker-related potassium channel alpha subunits
Neuron
1996
16: 455-463
|
| 29587458 |
Paley EL et al.:
Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration
|
| 29515443 |
Zuccarini M et al.:
Uncovering the Signaling Pathway behind Extracellular Guanine-Induced Activation of NO System: New Perspectives in Memory-Related Disorders
Front Pharmacol
2018
9: 110
|
| 11083230 |
Duelli R et al.:
Expression of large amino acid transporter LAT1 in rat brain endothelium
J. Cereb. Blood Flow Metab.
2000
20: 1557-1562
|
| 21641044 |
Tsuboi H et al.:
Val1483Ile polymorphism in the fatty acid synthase gene was associated with depressive symptoms under the influence of psychological stress
J Affect Disord
2011
134: 448-452
|
| 24507186 |
Herskovits AZ et al.:
SIRT1 in neurodevelopment and brain senescence
Neuron
2014
81: 471-483
|
| 22169038 |
Libert S et al. et al.:
SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive
Cell
2011
147: 1459-1472
|
| 30279456 |
Soiza-Reilly M et al.:
SSRIs target prefrontal to raphe circuits during development modulating synaptic connectivity and emotional behavior
|
| 18253134 |
Wilkie MJ et al.:
Polymorphisms in the SLC6A4 and HTR2A genes influence treatment outcome following antidepressant therapy
Pharmacogenomics J.
2009
9: 61-70
|
| 27693232 |
Shashi V et al. et al.:
De Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype
Am. J. Hum. Genet.
2016
99: 991-999
|
| 29667739 |
Tuovinen S et al. et al.:
Maternal depressive symptoms during and after pregnancy and child developmental milestones
Depress Anxiety
2018
35: 732-741
|
| 29679559 |
Newman EA et al.:
Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes
Dev. Biol.
2018
439: 102-111
|
| 28890143 |
Hoffmann HM et al.:
Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on the GnRH promoter controls Gnrh1 expression levels in a GnRH neuron maturation specific manner
Mol. Cell. Endocrinol.
2018
461: 143-154
|
| 15280216 |
Taglialatela P et al.:
Compromised generation of GABAergic interneurons in the brains of Vax1-/- mice
Development
2004
131: 4239-4249
|
| 20847275 |
Baudry A et al.:
miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants
Science
2010
329: 1537-1541
|
| 21531340 |
Lam DD et al. et al.:
Leptin does not directly affect CNS serotonin neurons to influence appetite
Cell Metab.
2011
13: 584-591
|
| 21187319 |
Yadav VK et al.:
Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications
J. Exp. Med.
2011
208: 41-52
|
| 19737523 |
Yadav VK et al. et al.:
A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure
Cell
2009
138: 976-989
|
| 20952540 |
Oury F et al.:
CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neurons
Genes Dev.
2010
24: 2330-2342
|
| 28626516 |
Abdel-Magid AF et al.:
Inhibitors of Adaptor-Associated Kinase 1 (AAK1) May Treat Neuropathic Pain, Schizophrenia, Parkinsons Disease, and Other Disorders
ACS Med Chem Lett
2017
8: 595-597
|
| 28341646 |
Schultz SA et al. et al.:
Cardiorespiratory fitness alters the influence of a polygenic risk score on biomarkers of AD
Neurology
2017
88: 1650-1658
|
| 31085646 |
Yook JS et al.:
Leptin in hippocampus mediates benefits of mild exercise by an antioxidant on neurogenesis and memory
|
| 26111766 |
Lin L et al.:
SLC transporters as therapeutic targets: emerging opportunities
Nat Rev Drug Discov
2015
14: 543-560
|
| 30958380 |
Costa AS et al.:
SNARE Complex Polymorphisms Associate with Alterations of Visual Selective Attention in Alzheimers Disease
J. Alzheimers Dis.
2019
69: 179-188
|
| 27156691 |
Dong L et al.:
The E3 Ubiquitin Ligase c-Cbl Inhibits Microglia-Mediated CNS Inflammation by Regulating PI3K/Akt/NF-kappaB Pathway
CNS Neurosci Ther
2016
22: 661-669
|
| 27170183 |
Homma Y et al.:
Rabin8 regulates neurite outgrowth in both GEF activity-dependent and -independent manners
Mol. Biol. Cell
2016
27: 2107-2118
|
| 21856246 |
Wang T et al.:
Lgl1 activation of rab10 promotes axonal membrane trafficking underlying neuronal polarization
Dev. Cell
2011
21: 431-444
|
| 26824392 |
Steger M et al. et al.:
Phosphoproteomics reveals that Parkinsons disease kinase LRRK2 regulates a subset of Rab GTPases
|
| 29183403 |
Ridge PG et al. et al.:
Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimers disease resilience
Genome Med
2017
9: 100
|
| 30398148 |
Dhekne HS et al.:
A pathway for Parkinsons Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain
|
| 30398148 |
Dhekne HS et al.:
A pathway for Parkinsons Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain
|
| 29310658 |
Shih YT et al.:
The involvement of endoplasmic reticulum formation and protein synthesis efficiency in VCP- and ATL1-related neurological disorders
J. Biomed. Sci.
2018
25: 2
|
| 26984393 |
Shih YT et al.:
VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation
Nat Commun
2016
7: 11020
|
| 30709655 |
Tang T et al.:
HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development
Neuron
2019
101: 1117-1133.e5
|
| 31138894 |
Hu Z et al.:
Genetic insights and neurobiological implications from NRXN1 in neuropsychiatric disorders
Mol Psychiatry
2019
24: 1400-1414
|
| 18270208 |
Nussbaum J et al.:
Significant association of the neurexin-1 gene (NRXN1) with nicotine dependence in European- and African-American smokers
Hum. Mol. Genet.
2008
17: 1569-1577
|
| 25609615 |
Genheden M et al.:
BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1
J. Neurosci.
2015
35: 972-984
|
| 23525215 |
Polman JA et al.:
Two populations of glucocorticoid receptor-binding sites in the male rat hippocampal genome
Endocrinology
2013
154: 1832-1844
|
| 26216298 |
Jenkins AK et al.:
Neurexin 1 (NRXN1) splice isoform expression during human neocortical development and aging
Mol. Psychiatry
2016
21: 701-706
|
| 11470830 |
Sugita S et al.:
A stoichiometric complex of neurexins and dystroglycan in brain
J. Cell Biol.
2001
154: 435-445
|
| 23358245 |
Pettem KL et al.:
Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development
J. Cell Biol.
2013
200: 321-336
|
| 22196734 |
Iijima T et al.:
SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1
Cell
2011
147: 1601-1614
|
| 23536886 |
Zeng L et al.:
Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models
PLoS ONE
2013
8
|
| 16242404 |
Boucard AA et al.:
A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins
Neuron
2005
48: 229-236
|
| 12827191 |
Missler M et al.:
Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis
Nature
2003
423: 939-948
|
| 25481834 |
Prajapati P et al.:
TNF-alpha regulates miRNA targeting mitochondrial complex-I and induces cell death in dopaminergic cells
Biochim. Biophys. Acta
2015
1852: 451-461
|
| 30584462 |
Urbainsky C et al.:
Nucleoredoxin-Dependent Targets and Processes in Neuronal Cells
Oxid Med Cell Longev
2018
2018
|
| 9759920 |
Mossner R et al.:
Enhancement of serotonin transporter function by tumor necrosis factor alpha but not by interleukin-6
Neurochem. Int.
1998
33: 251-254
|
| 20542150 |
Gijsbers AC et al.:
Additional cryptic CNVs in mentally retarded patients with apparently balanced karyotypes
Eur J Med Genet
2010
53: 227-233
|
| 23254357 |
Snir O et al.:
Genetic variation in the serotonin receptor gene affects immune responses in rheumatoid arthritis
Genes Immun.
2013
14: 83-89
|
| 22907732 |
Lohoff FW et al.:
Interaction between polymorphisms in serotonin transporter (SLC6A4) and serotonin receptor 2A (HTR2A) genes predict treatment response to venlafaxine XR in generalized anxiety disorder
Pharmacogenomics J.
2013
13: 464-469
|
| 15606893 |
Chen F et al.:
Characterization of an allosteric citalopram-binding site at the serotonin transporter
J. Neurochem.
2005
92: 21-28
|
| 22717018 |
Lenze EJ et al.:
Escitalopram reduces attentional performance in anxious older adults with high-expression genetic variants at serotonin 2A and 1B receptors
Int. J. Neuropsychopharmacol.
2013
16: 279-288
|
| 23411676 |
Quesseveur G et al.:
5-HT(2)A receptor inactivation potentiates the acute antidepressant-like activity of escitalopram: involvement of the noradrenergic system
Exp Brain Res
2013
226: 285-295
|
| 27102954 |
Amos JS et al. et al.:
Autosomal recessive mutations in THOC6 cause intellectual disability: syndrome delineation requiring forward and reverse phenotyping
Clin Genet
2017
91: 92-99
|
| 19615339 |
Oh-hashi K et al.:
CRELD2 is a novel endoplasmic reticulum stress-inducible gene
Biochem Biophys Res Commun
2009
387: 504-510
|
| 16238698 |
Ortiz JA et al.:
The cysteine-rich with EGF-like domains 2 (CRELD2) protein interacts with the large cytoplasmic domain of human neuronal nicotinic acetylcholine receptor alpha4 and beta2 subunits
J Neurochem
2005
95: 1585-1596
|
| 28102201 |
Anderluh A et al.:
Direct PIP2 binding mediates stable oligomer formation of the serotonin transporter
Nat Commun
2017
8: 14089
|
| 16697352 |
Myers RL et al.:
Polymorphisms in the regulatory region of the human serotonin 5-HT2A receptor gene (HTR2A) influence gene expression
Biol. Psychiatry
2007
61: 167-173
|
| 28270751 |
Borroto-Escuela DO et al. et al.:
Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease
Front Cell Neurosci
2017
11: 37
|
| 28779001 |
author information missing
article information missing
|
| 26235277 |
author information missing
article information missing
|
| 21040848 |
Burgalossi A et al.:
SNARE protein recycling by alphaSNAP and betaSNAP supports synaptic vesicle priming
Neuron
2010
68: 473-487
|
| 28459524 |
Becamel C et al.:
Growing Evidence for Heterogeneous Synaptic Localization of 5-HT2A Receptors
ACS Chem Neurosci
2017
8: 897-899
|
| 27140629 |
Zhang YW et al.:
Control of serotonin transporter phosphorylation by conformational state
Proc. Natl. Acad. Sci. U.S.A.
2016
113
|
| 21419114 |
McNeill EM et al.:
Nav2 hypomorphic mutant mice are ataxic and exhibit abnormalities in cerebellar development
Dev. Biol.
2011
353: 331-343
|
| 23845563 |
Henry ME et al.:
Effects of citalopram and escitalopram on fMRI response to affective stimuli in healthy volunteers selected by serotonin transporter genotype
Psychiatry Res
2013
213: 217-224
|
| 29724652 |
Chen B et al.:
A novel homozygous NDRG1 mutation in a Chinese patient with Charcot-Marie-Tooth disease 4D
J Clin Neurosci
2018
53: 231-234
|
| 17142040 |
Echaniz-Laguna A et al.:
NDRG1-linked Charcot-Marie-Tooth disease (CMT4D) with central nervous system involvement
Neuromuscul. Disord.
2007
17: 163-168
|
| 15082788 |
Okuda T et al.:
Ndrg1-deficient mice exhibit a progressive demyelinating disorder of peripheral nerves
Mol. Cell. Biol.
2004
24: 3949-3956
|
| 11072102 |
Dalski A et al.:
Quantitative PCR analysis of different splice forms of NFAT5 revealed specific gene expression in fetal and adult brain
Brain Res. Mol. Brain Res.
2000
83: 125-127
|
| 20877715 |
Kleinschnitz C et al. et al.:
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration
|
| 17497724 |
Garver WS et al.:
The National Niemann-Pick C1 disease database: report of clinical features and health problems
Am. J. Med. Genet. A
2007
143
|
| 30809118 |
Baudry A et al.:
Multifaceted Regulations of the Serotonin Transporter: Impact on Antidepressant Response
Front Neurosci
2019
13: 91
|
| 21246047 |
Song NN et al.:
Adult raphe-specific deletion of Lmx1b leads to central serotonin deficiency
PLoS ONE
2011
6
|
| 20210852 |
Matheus N et al.:
Melatonin inhibits serotonin transporter activity in intestinal epithelial cells
J. Pineal Res.
2010
48: 332-339
|
| 18581270 |
Fjorback AW et al.:
Membrane glycoprotein M6B interacts with the human serotonin transporter
J. Mol. Neurosci.
2009
37: 191-200
|
| 22572884 |
Ushijima K et al.:
Role of activating transcription factor-4 in 24-hour rhythm of serotonin transporter expression in the mouse midbrain
Mol. Pharmacol.
2012
82: 264-270
|
| 22445341 |
Ultanir SK et al.:
Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development
Neuron
2012
73: 1127-1142
|
| 31243174 |
Lin YT et al.:
Neuropeptide FF modulates neuroendocrine and energy homeostasis through hypothalamic signaling
Chin J Physiol
2019
62: 47-52
|
| 20628354 |
Jurado S et al.:
PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression
EMBO J.
2010
29: 2827-2840
|
| 22353733 |
Patel AV et al.:
Neurotrophin-4 regulates the survival of gustatory neurons earlier in development using a different mechanism than brain-derived neurotrophic factor
Dev. Biol.
2012
365: 50-60
|
| 20407817 |
Shen Y et al.:
Neurotrophin-4 (ntf4) mediates neurogenesis in mouse embryonic neural stem cells through the inhibition of the signal transducer and activator of transcription-3 (stat3) and the modulation of the activity of protein kinase B
Cell. Mol. Neurobiol.
2010
30: 909-916
|
| 25851806 |
Li X et al.:
Five Chinese patients with 5-oxoprolinuria due to glutathione synthetase and 5-oxoprolinase deficiencies
Brain Dev.
2015
37: 952-959
|
| 20435134 |
Tseveleki V et al.:
Comparative gene expression analysis in mouse models for multiple sclerosis, Alzheimers disease and stroke for identifying commonly regulated and disease-specific gene changes
Genomics
2010
96: 82-91
|
| 28426234 |
Barake R et al.:
The OTOGL p.Arg925* Variant is Associated with Moderate Hearing Loss in a Syrian Nonconsanguineous Family
Genet Test Mol Biomarkers
2017
21: 445-449
|
| 28742274 |
Ma D et al.:
Whole exome sequencing identified genetic variations in Chinese hemangioblastoma patients
Am. J. Med. Genet. A
2017
173: 2605-2613
|
| 31537871 |
Aslam M et al. et al.:
Segregation and potential functional impact of a rare stop-gain PABPC4L variant in familial atypical Parkinsonism
Sci Rep
2019
9: 13576
|
| 28973305 |
Agarwal AK et al.:
Metabolic, Reproductive, and Neurologic Abnormalities in Agpat1-Null Mice
Endocrinology
2017
158: 3954-3973
|
| 28126482 |
de Campos-Carli SM et al.:
Serum levels of interleukin-33 and its soluble form receptor (sST2) are associated with cognitive performance in patients with schizophrenia
Compr Psychiatry
2017
74: 96-101
|
| 22037555 |
Shi Y et al. et al.:
Common variants on 8p12 and 1q24.2 confer risk of schizophrenia
Nat. Genet.
2011
43: 1224-1227
|
| 29213114 |
Wischhof L et al. et al.:
The SWI/SNF subunit Bcl7a contributes to motor coordination and Purkinje cell function
Sci Rep
2017
7: 17055
|
| 26498236 |
Winkelman JW et al.:
Genetic associations of periodic limb movements of sleep in the elderly for the MrOS sleep study
Sleep Med.
2015
16: 1360-1365
|
| 22536397 |
DeAndrade MP et al.:
Enhanced hippocampal long-term potentiation and fear memory in Btbd9 mutant mice
PLoS ONE
2012
7
|
| 10727730 |
Nishinaka N et al.:
Identification of the novel developmentally regulated gene, Bdm2, which is highly expressed in fetal rat brain
Brain Res. Dev. Brain Res.
2000
120: 57-64
|
| 27110435 |
Krishnan ML et al.:
Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants
Brain Behav
2016
6
|
| 23759691 |
Nagahara N et al.:
Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria
Sci Rep
2013
3: 1986
|
| 25786798 |
Shen T et al.:
CHD2 is Required for Embryonic Neurogenesis in the Developing Cerebral Cortex
Stem Cells
2015
33: 1794-1806
|
| 18539113 |
Lupu F et al.:
Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo
Dev. Cell
2008
14: 831-842
|
| 29305086 |
Molinard-Chenu A et al.:
The Candidate Schizophrenia Risk Gene DGCR2 Regulates Early Steps of Corticogenesis
Biol Psychiatry
2018
83: 692-706
|
| 7633403 |
Demczuk S et al.:
Cloning of a balanced translocation breakpoint in the DiGeorge syndrome critical region and isolation of a novel potential adhesion receptor gene in its vicinity
Hum Mol Genet
1995
4: 551-558
|
| 26216346 |
Thijssen PE et al. et al.:
Mutations in CDCA7 and HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome
Nat Commun
2015
6: 7870
|
| 28239766 |
Miao Q et al.:
Up-regulation of GBP2 is Associated with Neuronal Apoptosis in Rat Brain Cortex Following Traumatic Brain Injury
Neurochem. Res.
2017
42: 1515-1523
|
| 16271034 |
Gening LV et al.:
Enhanced activity of DNA polymerase iota in mouse brain cells is associated with aggressiveness
Biochemistry Mosc.
2005
70: 1157-1162
|
| 28575017 |
Rasnitsyn A et al.:
FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25
PLoS ONE
2017
12
|
| 29576217 |
Mendes MI et al. et al.:
Bi-allelic Mutations in EPRS, Encoding the Glutamyl-Prolyl-Aminoacyl-tRNA Synthetase, Cause a Hypomyelinating Leukodystrophy
Am. J. Hum. Genet.
2018
102: 676-684
|
| 25336657 |
Dikopoltsev E et al.:
FBXO22 protein is required for optimal synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine
J. Biol. Chem.
2014
289
|
| 15893606 |
Matsuki T et al.:
Gene expression profiling during the embryonic development of mouse brain using an oligonucleotide-based microarray system
Brain Res Mol Brain Res
2005
136: 231-254
|
| 20682460 |
Edvardson S et al.:
l-arginine:glycine amidinotransferase (AGAT) deficiency: clinical presentation and response to treatment in two patients with a novel mutation
Mol. Genet. Metab.
2010
101: 228-232
|
| 16769397 |
Battini R et al.:
Arginine:glycine amidinotransferase (AGAT) deficiency in a newborn: early treatment can prevent phenotypic expression of the disease
J. Pediatr.
2006
148: 828-830
|
| 12701824 |
Schulze A et al.:
Creatine deficiency syndromes
Mol. Cell. Biochem.
2003
244: 143-150
|
| 24705253 |
Mirzaa G et al. et al.:
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome
Nat Genet
2014
46: 510-515
|
| 28512781 |
Kersten S et al.:
Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
J. Clin. Invest.
1999
103: 1489-1498
|
| 24161943 |
Marzinke MA et al.:
14-3-3epsilon and NAV2 interact to regulate neurite outgrowth and axon elongation
Arch. Biochem. Biophys.
2013
540: 94-100
|
| 27838821 |
Xia X et al.:
NFAT5 protects astrocytes against oxygen-glucose-serum deprivation/restoration damage via the SIRT1/Nrf2 pathway
J Mol Neurosci
2017
61: 96-104
|
| 30654674 |
Skibinska M et al.:
Correlation of metabolic parameters, neurotrophin-3, and neurotrophin-4 serum levels in women with schizophrenia and first-onset depression
Nord J Psychiatry
2019
73: 96-103
|
| 26223428 |
Gawlik M et al.:
The role of Pannexin gene variants in schizophrenia: systematic analysis of phenotypes
Eur Arch Psychiatry Clin Neurosci
2016
266: 433-437
|
| 23161870 |
Pang Y et al.:
Characterization, neurosteroid binding and brain distribution of human membrane progesterone receptors delta and {epsilon} (mPRdelta and mPR{epsilon}) and mPRdelta involvement in neurosteroid inhibition of apoptosis
Endocrinology
2013
154: 283-295
|
| 28191889 |
Stessman HA et al. et al.:
Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases
Nat. Genet.
2017
49: 515-526
|
| 30768381 |
Phillips OR et al.:
Beyond a Binary Classification of Sex: An Examination of Brain Sex Differentiation, Psychopathology, and Genotype
J Am Acad Child Adolesc Psychiatry
2019
58: 787-798
|
| 22450339 |
Kasnauskiene J et al.:
A single gene deletion on 4q28.3: PCDH18--a new candidate gene for intellectual disability?
Eur J Med Genet
2012
55: 274-277
|
| 18468594 |
Aamar E et al.:
Protocadherin-18a has a role in cell adhesion, behavior and migration in zebrafish development
Dev. Biol.
2008
318: 335-346
|
| 29779877 |
Mire E et al.:
Developmental Upregulation of Ephrin-B1 Silences Sema3C/Neuropilin-1 Signaling during Post-crossing Navigation of Corpus Callosum Axons
Curr. Biol.
2018
28: 1768-1782.e4
|
| 17336976 |
Al-Sayed M et al.:
Preimplantation genetic diagnosis for Zellweger syndrome
Fertil. Steril.
2007
87: 1468.e1-1468.e3
|
| 12851857 |
Matsumoto N et al.:
Mutations in novel peroxin gene PEX26 that cause peroxisome-biogenesis disorders of complementation group 8 provide a genotype-phenotype correlation
Am. J. Hum. Genet.
2003
73: 233-246
|
| 27280679 |
Auderset L et al.:
Low Density Lipoprotein-Receptor Related Protein 1 Is Differentially Expressed by Neuronal and Glial Populations in the Developing and Mature Mouse Central Nervous System
PLoS ONE
2016
11
|
| 24269040 |
Ramos-Quiroga JA et al. et al.:
Genome-wide copy number variation analysis in adult attention-deficit and hyperactivity disorder
J Psychiatr Res
2014
49: 60-67
|
| 22710270 |
Velez JI et al. et al.:
Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimers disease
Mol. Psychiatry
2013
18: 568-575
|
| 24333148 |
Mlyniec K et al.:
The involvement of the GPR39-Zn(2+)-sensing receptor in the pathophysiology of depression. Studies in rodent models and suicide victims
Neuropharmacology
2014
79: 290-297
|
| 25609596 |
Mlyniec K et al.:
GPR39 (zinc receptor) knockout mice exhibit depression-like behavior and CREB/BDNF down-regulation in the hippocampus
|
| 20837536 |
Vaishnavi SN et al.:
Regional aerobic glycolysis in the human brain
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 24407245 |
Perez-Mato M et al.:
Human recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia
Cell Death Dis
2014
5: e992
|
| 19229853 |
Unschuld PG et al.:
Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2009
150
|
| 23373770 |
Martin S et al.:
Deficiency of G3BP1, the stress granules assembly factor, results in abnormal synaptic plasticity and calcium homeostasis in neurons
J. Neurochem.
2013
125: 175-184
|
| 11522384 |
Marionneau S et al.:
ABH and Lewis histo-blood group antigens, a model for the meaning of oligosaccharide diversity in the face of a changing world
Biochimie
2001
83: 565-573
|
| 19527073 |
Murrey HE et al.:
Identification of the plasticity-relevant fucose-alpha(1-2)-galactose proteome from the mouse olfactory bulb
Biochemistry
2009
48: 7261-7270
|
| 20838396 |
Chen X et al. et al.:
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia
Mol. Psychiatry
2011
16: 1117-1129
|
| 24207122 |
Sumner CJ et al. et al.:
A dominant mutation in FBXO38 causes distal spinal muscular atrophy with calf predominance
Am. J. Hum. Genet.
2013
93: 976-983
|
| 31420593 |
Akcimen F et al.:
A novel homozygous FBXO38 variant causes an early-onset distal hereditary motor neuronopathy type IID
J. Hum. Genet.
2019
64: 1141-1144
|
| 21822260 |
author information missing
Magnetic manipulation of self-assembled colloidal asters
Nat Mater
2011
10: 698-703
|
| 19405097 |
Ali AM et al.:
Identification and characterization of mutations in FANCL gene: a second case of Fanconi anemia belonging to FA-L complementation group
Hum. Mutat.
2009
30: E761-E770
|
| 25446406 |
Vodopiutz J et al.:
MED20 mutation associated with infantile basal ganglia degeneration and brain atrophy
Eur. J. Pediatr.
2015
174: 113-118
|
| 31639064 |
Spindola LM et al. et al.:
Detecting multiple differentially methylated CpG sites and regions related to dimensional psychopathology in youths
Clin Epigenetics
2019
11: 146
|
| 27559088 |
Guo X et al.:
Rab5 and its effector FHF contribute to neuronal polarity through dynein-dependent retrieval of somatodendritic proteins from the axon
Proc. Natl. Acad. Sci. U.S.A.
2016
113
|
| 16691597 |
Spruijt L et al.:
Identification of a novel EYA1 mutation presenting in a newborn with laryngomalacia, glossoptosis, retrognathia, and pectus excavatum
Am. J. Med. Genet. A
2006
140: 1343-1345
|
| 30908667 |
Men M et al.:
Identification of a Novel CNV at 8q13 in a Family With Branchio-Oto-Renal Syndrome and Epilepsy
Laryngoscope
2020
130: 526-532
|
| 15817220 |
Friedman RA et al.:
Eya1 acts upstream of Tbx1, Neurogenin 1, NeuroD and the neurotrophins BDNF and NT-3 during inner ear development
Mech. Dev.
2005
122: 625-634
|
| 20503367 |
Freyer L et al.:
Canonical Wnt signaling modulates Tbx1, Eya1, and Six1 expression, restricting neurogenesis in the otic vesicle
Dev. Dyn.
2010
239: 1708-1722
|
| 25816987 |
Eisner A et al.:
The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis
Dev. Cell
2015
33: 22-35
|
| 22700954 |
Dixon-Salazar TJ et al. et al.:
Exome sequencing can improve diagnosis and alter patient management
Sci Transl Med
2012
4: 138ra78
|
| 31665629 |
Moretto E et al. et al.:
TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering
Cell Rep
2019
29: 1130-1146.e8
|
| 20339380 |
Chu TT et al.:
An integrated genomic analysis of gene-function correlation on schizophrenia susceptibility genes
J. Hum. Genet.
2010
55: 285-292
|
| 3459695 |
author information missing
Evidence for linkage between Wilson disease and esterase D in three kindreds: detection of linkage for an autosomal recessive disorder by the family study method
Genet. Epidemiol.
1986
3: 201-209
|
| 23752245 |
Hooli BV et al.:
Rare autosomal copy number variations in early-onset familial Alzheimers disease
Mol. Psychiatry
2014
19: 676-681
|
| 31500865 |
Chi L et al.:
miR-9-5p attenuates ischemic stroke through targeting ERMP1-mediated endoplasmic reticulum stress
Acta Histochem.
2019
121
|
| 15068237 |
Shim KS et al.:
Aberrant protein expression of transcription factors BACH1 and ERG, both encoded on chromosome 21, in brains of patients with Down syndrome and Alzheimers disease
|
| 22159054 |
Logue MW et al. et al.:
A comprehensive genetic association study of Alzheimer disease in African Americans
Arch. Neurol.
2011
68: 1569-1579
|
| 22744667 |
Landoure G et al. et al.:
A candidate gene for autoimmune myasthenia gravis
Neurology
2012
79: 342-347
|
| 29179725 |
Grunblatt E et al.:
High resolution chromosomal microarray analysis in paediatric obsessive-compulsive disorder
BMC Med Genomics
2017
10: 68
|
| 28696314 |
Diamantopoulou A et al.:
Loss-of-function mutation in Mirta22/Emc10 rescues specific schizophrenia-related phenotypes in a mouse model of the 22q11.2 deletion
Proc. Natl. Acad. Sci. U.S.A.
2017
114
|
| 24550128 |
Saywell V et al.:
Developmental gene expression profile of axon guidance cues in Purkinje cells during cerebellar circuit formation
Cerebellum
2014
13: 307-317
|
| 19772933 |
Reddy S et al.:
A novel 1.4 Mb de novo microdeletion of chromosome 1q21.3 in a child with microcephaly, dysmorphic features and mental retardation
Eur J Med Genet
2009
52: 443-445
|
| 29990673 |
Zhao XN et al.:
FAN1 protects against repeat expansions in a Fragile X mouse model
DNA Repair (Amst.)
2018
69: 1-5
|
| 24282185 |
Beal JC et al.:
Case report: Neuronal migration disorder associated with chromosome 15q13.3 duplication in a boy with autism and seizures
J. Child Neurol.
2014
29: NP186-NP188
|
| 15173237 |
author information missing
Selective disruption of muscle and brain-specific BPAG1 isoforms in a girl with a 6;15 translocation, cognitive and motor delay, and tracheo-oesophageal atresia
J. Med. Genet.
2004
41: e71
|
| 27633915 |
Gebhardt C et al.:
A novel form of capsaicin-modified amygdala LTD mediated by TRPM1
Neurobiol Learn Mem
2016
136: 1-12
|
| 25701870 |
Ahmed I et al. et al.:
Mutations in DCPS and EDC3 in autosomal recessive intellectual disability indicate a crucial role for mRNA decapping in neurodevelopment
Hum. Mol. Genet.
2015
24: 3172-3180
|
| 27092053 |
Guidotti A et al.:
Epigenetic RELN Dysfunction in Schizophrenia and Related Neuropsychiatric Disorders
Front Cell Neurosci
2016
10: 89
|
| 23176821 |
Tesson C et al. et al.:
Alteration of fatty-acid-metabolizing enzymes affects mitochondrial form and function in hereditary spastic paraplegia
Am. J. Hum. Genet.
2012
91: 1051-1064
|
| 9486994 |
Kitanaka S et al.:
Inactivating mutations in the 25-hydroxyvitamin D3 1alpha-hydroxylase gene in patients with pseudovitamin D-deficiency rickets
N. Engl. J. Med.
1998
338: 653-661
|
| 15300631 |
Ma YN et al.:
[Five single nucleotide polymorphisms of casein kinase I gamma 2 gene in children with familial febrile convulsions]
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
2004
21: 347-350
|
| 26184558 |
Quintana E et al.:
DNGR-1(+) dendritic cells are located in meningeal membrane and choroid plexus of the noninjured brain
Glia
2015
63: 2231-2248
|
| 28344005 |
Gao F et al. et al.:
miR-342-5p Regulates Neural Stem Cell Proliferation and Differentiation Downstream to Notch Signaling in Mice
Stem Cell Reports
2017
8: 1032-1045
|
| 24999027 |
Chen HR et al.:
Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression
Exp. Neurol.
2014
261: 10-21
|
| 21543638 |
Knight WD et al.:
Chronic intermittent hypoxia increases blood pressure and expression of FosB/DeltaFosB in central autonomic regions
Am. J. Physiol. Regul. Integr. Comp. Physiol.
2011
301: R131-R139
|
| 14716021 |
Konishi Y et al.:
Cdh1-APC controls axonal growth and patterning in the mammalian brain
Science
2004
303: 1026-1030
|
| 19900895 |
Yang Y et al.:
A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation
Science
2009
326: 575-578
|
| 21490919 |
Liu Z et al.:
CASZ1b, the short isoform of CASZ1 gene, coexpresses with CASZ1a during neurogenesis and suppresses neuroblastoma cell growth
PLoS ONE
2011
6
|
| 15084659 |
Wayman GA et al.:
Regulation of axonal extension and growth cone motility by calmodulin-dependent protein kinase I
J. Neurosci.
2004
24: 3786-3794
|
| 28178528 |
Frese CK et al.:
Quantitative Map of Proteome Dynamics during Neuronal Differentiation
Cell Rep
2017
18: 1527-1542
|
| 18988906 |
Austinat M et al.:
Blockade of bradykinin receptor B1 but not bradykinin receptor B2 provides protection from cerebral infarction and brain edema
Stroke
2009
40: 285-293
|
| 19095966 |
Niizuma K et al.:
Potential role of PUMA in delayed death of hippocampal CA1 neurons after transient global cerebral ischemia
Stroke
2009
40: 618-625
|
| 28493104 |
Shahrour MA et al.:
Hypomyelinating leukodystrophy associated with a deleterious mutation in the ATRN gene
Neurogenetics
2017
18: 135-139
|
| 11209055 |
Kuramoto T et al. et al.:
Attractin/mahogany/zitter plays a critical role in myelination of the central nervous system
Proc. Natl. Acad. Sci. U.S.A.
2001
98: 559-564
|
| 19646677 |
Newbury DF et al. et al.:
CMIP and ATP2C2 modulate phonological short-term memory in language impairment
Am. J. Hum. Genet.
2009
85: 264-272
|
| 28214564 |
Hirayama-Kurogi M et al. et al.:
Downregulation of GNA13-ERK network in prefrontal cortex of schizophrenia brain identified by combined focused and targeted quantitative proteomics
J Proteomics
2017
158: 31-42
|
| 32165008 |
Alazami AM et al. et al.:
Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families
Cell Rep
2015
10: 148-161
|
| 12145310 |
Swain E et al.:
Yeast cells lacking the ARV1 gene harbor defects in sphingolipid metabolism. Complementation by human ARV1
J. Biol. Chem.
2002
277
|
| 22182939 |
Nguyen LS et al. et al.:
Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability
Mol. Psychiatry
2012
17: 1103-1115
|
| 21620353 |
Abou Jamra R et al. et al.:
Adaptor protein complex 4 deficiency causes severe autosomal-recessive intellectual disability, progressive spastic paraplegia, shy character, and short stature
Am. J. Hum. Genet.
2011
88: 788-795
|
| 25612138 |
Garcia-Martin E et al.:
Diamine oxidase rs10156191 and rs2052129 variants are associated with the risk for migraine
Headache
2015
55: 276-286
|
| 32127521 |
Liang W et al.:
Variants of GRM7 as risk factor and response to antipsychotic therapy in schizophrenia
Transl Psychiatry
2020
10: 83
|
| 31540917 |
Ocasio JK et al.:
GSK-3 modulates SHH-driven proliferation in postnatal cerebellar neurogenesis and medulloblastoma
|
| 29378302 |
Vargas LM et al.:
Amyloid-beta oligomers synaptotoxicity: The emerging role of EphA4/c-Abl signaling in Alzheimers disease
Biochim Biophys Acta Mol Basis Dis
2018
1864: 1148-1159
|
| 30446579 |
Tanaka AJ et al.:
A newly identified mutation in the PEX26 gene is associated with a milder form of Zellweger spectrum disorder
|
| 28009295 |
Ehrmann I et al. et al.:
A SLM2 Feedback Pathway Controls Cortical Network Activity and Mouse Behavior
Cell Rep
2016
17: 3269-3280
|
| 31287605 |
Hu YB et al.:
Rho-associated coiled-coil kinase 1 activation mediates amyloid precursor protein site-specific Ser655 phosphorylation and triggers amyloid pathology
Aging Cell
2019
18
|
| 29315334 |
Broce I et al. et al.:
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
PLoS Med.
2018
15
|
| 31548203 |
Sceniak MP et al.:
An autism-associated mutation in GluN2B prevents NMDA receptor trafficking and interferes with dendrite growth
|
| 26656067 |
Wei B et al.:
Hippocampal NMDAR-Wnt-Catenin signaling disrupted with cognitive deficits in adolescent offspring exposed to prenatal hypoxia
Brain Res.
2016
1631: 157-164
|
| 25206584 |
Li C et al.:
Global view of transcriptome in the brains of aged NR2B transgenic mice
Neural Regen Res
2013
8: 2734-2743
|
| 25921811 |
Xia W et al.:
GRM7 regulates embryonic neurogenesis via CREB and YAP
Stem Cell Reports
2015
4: 795-810
|
| 9920659 |
Masugi M et al.:
Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion
J. Neurosci.
1999
19: 955-963
|
| 26932439 |
Gu X et al.:
GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons
Nat Commun
2016
7: 10873
|
| 16054170 |
Coppede F et al.:
Molecular implications of the human glutathione transferase A-4 gene (hGSTA4) polymorphisms in neurodegenerative diseases
Mutat. Res.
2005
579: 107-114
|
| 28672859 |
Jewett M et al.:
Astrocytic Expression of GSTA4 Is Associated to Dopaminergic Neuroprotection in a Rat 6-OHDA Model of Parkinsons Disease
|
| 26247729 |
Song J et al.:
Adiponectin receptor-mediated signaling ameliorates cerebral cell damage and regulates the neurogenesis of neural stem cells at high glucose concentrations: an in vivo and in vitro study
Cell Death Dis
2015
6: e1844
|
| 32188008 |
Rizzo MR et al.:
Adiponectin and Cognitive Decline
|
| 20921022 |
Wat MJ et al.:
Recurrent microdeletions of 15q25.2 are associated with increased risk of congenital diaphragmatic hernia, cognitive deficits and possibly Diamond--Blackfan anaemia
J. Med. Genet.
2010
47: 777-781
|
| 20890995 |
Abouzied MM et al.:
Hepatoma-derived growth factor-related protein-3: a new neurotrophic and neurite outgrowth-promoting factor for cortical neurons
J. Neurosci. Res.
2010
88: 3610-3620
|
| 30667096 |
Tanga N et al.:
The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice
Glia
2019
67: 967-984
|
| 12629050 |
Kuja-Panula J et al.:
AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats
J. Cell Biol.
2003
160: 963-973
|
| 26240432 |
Peltola MA et al.:
AMIGO-Kv2.1 Potassium Channel Complex Is Associated With Schizophrenia-Related Phenotypes
Schizophr Bull
2016
42: 191-201
|
| 28588446 |
Ding M et al.:
Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay
Front Mol Neurosci
2017
10: 121
|
| 29130397 |
Fu Y et al.:
HIPK3 modulates autophagy and HTT protein levels in neuronal and mouse models of Huntington disease
Autophagy
2018
14: 169-170
|
| 31236915 |
Pilch J et al.:
Evidence for HNRNPH1 being another gene for Bain type syndromic mental retardation
Clin. Genet.
2018
94: 381-385
|
| 27117401 |
Grammatikakis I et al.:
Alternative Splicing of Neuronal Differentiation Factor TRF2 Regulated by HNRNPH1/H2
Cell Rep
2016
15: 926-934
|
| 27451434 |
Tsai WC et al.:
ARID4B is a good biomarker to predict tumour behaviour and decide WHO grades in gliomas and meningiomas
J. Clin. Pathol.
2017
70: 162-167
|
| 28320970 |
Farias GG et al.:
BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon
Proc. Natl. Acad. Sci. U.S.A.
2017
114
|
| 30663934 |
Xu XF et al.:
miR-151-5p modulates APH1a expression to participate in contextual fear memory formation
RNA Biol
2019
16: 282-294
|
| 25828470 |
Lin SH et al.:
Genetic mapping of ASIC4 and contrasting phenotype to ASIC1a in modulating innate fear and anxiety
Eur. J. Neurosci.
2015
41: 1553-1568
|
| 16437572 |
Janson CG et al. et al.:
Mild-onset presentation of Canavans disease associated with novel G212A point mutation in aspartoacylase gene
Ann Neurol
2006
59: 428-431
|
| 20360680 |
Schlager MA et al.:
Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis
EMBO J.
2010
29: 1637-1651
|
| 26301327 |
Korb E et al.:
BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice
Nat. Neurosci.
2015
18: 1464-1473
|
| 24421390 |
Wang JY et al.:
The capable ABL: what is its biological function?
Mol. Cell. Biol.
2014
34: 1188-1197
|
| 24061537 |
Garcez RC et al.:
Combinatorial activity of Six1-2-4 genes in cephalic neural crest cells controls craniofacial and brain development
Cell. Mol. Life Sci.
2014
71: 2149-2164
|
| 10827173 |
Gotthardt M et al.:
Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction
J. Biol. Chem.
2000
275
|
| 25533347 |
Hori K et al. et al.:
Cytoskeletal regulation by AUTS2 in neuronal migration and neuritogenesis
Cell Rep
2014
9: 2166-2179
|
| 8663493 |
Wong EV et al.:
Involvement of p90rsk in neurite outgrowth mediated by the cell adhesion molecule L1
J. Biol. Chem.
1996
271
|
| 11222645 |
ChenJH et al.:
The N-terminal leucine-rich regions in Slit are sufficient to repel olfactory bulb axons and subventricular zone neurons
J. Neurosci.
2001
21: 1548-1556
|
| 22783168 |
Sharma A et al.:
Receptor complexes for each of the Class 3 Semaphorins
Front Cell Neurosci
2012
6: 28
|
| 19143832 |
Camargo N et al.:
SREBPs: SREBP function in glia-neuron interactions
FEBS J.
2009
276: 628-636
|
| 19755105 |
Mandai K et al.:
LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development
Neuron
2009
63: 614-627
|
| 22475800 |
Popovics P et al.:
Phospholipase C-eta activity may contribute to Alzheimers disease-associated calciumopathy
J. Alzheimers Dis.
2012
30: 737-744
|
| 23201681 |
Knobloch M et al. et al.:
Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis
Nature
2013
493: 226-230
|
| 25748173 |
Lee JR et al.:
Protein tyrosine phosphatase PTPRT as a regulator of synaptic formation and neuronal development
BMB Rep
2015
48: 249-255
|
| 24041943 |
Pereira MG et al.:
Angiotensin II-independent angiotensin-(1-7) formation in rat hippocampus: involvement of thimet oligopeptidase
Hypertension
2013
62: 879-885
|
| 26354911 |
Ammendrup-Johnsen I et al.:
Neurotrophin-3 Enhances the Synaptic Organizing Function of TrkC-Protein Tyrosine Phosphatase sigma in Rat Hippocampal Neurons
J. Neurosci.
2015
35
|
| 26916325 |
Munoz A et al.:
[X-linked hereditary spastic paraplegia due to mutation in the L1CAM gene: three cases reports of CRASH syndrome]
Rev Neurol
2016
62: 218-222
|
| 27288825 |
Ramos-Molina B et al.:
PCSK1 Variants and Human Obesity
Prog Mol Biol Transl Sci
2016
140: 47-74
|
| 28239339 |
Yi S et al.:
Microarray and qPCR Analyses of Wallerian Degeneration in Rat Sciatic Nerves
Front Cell Neurosci
2017
11: 22
|
| 29198128 |
author information missing
Proprotein convertase 1 mediated proneuropeptide proteolytic processing in ischemic neuron injury
Bratisl Lek Listy
2017
118: 609-612
|
| 29549646 |
Lin YJ et al.:
NTF3 Is a Novel Target Gene of the Transcription Factor POU3F2 and Is Required for Neuronal Differentiation
Mol. Neurobiol.
2018
55: 8403-8413
|
| 31392959 |
Johnson V et al.:
Temporal regulation of axonal repulsion by alternative splicing of a conserved microexon in mammalian Robo1 and Robo2
|
| 14715136 |
Niu S et al.:
Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway
Neuron
2004
41: 71-84
|
| 15703255 |
Schmid RS et al.:
Reelin, integrin and DAB1 interactions during embryonic cerebral cortical development
Cereb. Cortex
2005
15: 1632-1636
|
| 28512108 |
Xu J et al.:
Clinical Relevance and Role of Neuronal AT1 Receptors in ADAM17-Mediated ACE2 Shedding in Neurogenic Hypertension
Circ. Res.
2017
121: 43-55
|
| 20534675 |
Honma Y et al.:
Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret
Development
2010
137: 2319-2328
|
| 29739947 |
Abudureyimu S et al.:
Essential Role of Linx/Islr2 in the Development of the Forebrain Anterior Commissure
Sci Rep
2018
8: 7292
|
| 28102469 |
Upadhyay A et al.:
Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases
Mol. Neurobiol.
2018
55: 1169-1182
|
| 27384491 |
Kim SJ et al.:
The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus
Oncotarget
2016
7
|
| 12629050 |
Kuja-Panula J et al.:
AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats
J Cell Biol
2003
160: 963-973
|
| 10781943 |
Rohm B et al.:
Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A
Mech. Dev.
2000
93: 95-104
|
| 21508241 |
Hernandez-Miranda LR et al.:
Robo1 regulates semaphorin signaling to guide the migration of cortical interneurons through the ventral forebrain
J. Neurosci.
2011
31: 6174-6187
|
| 15550985 |
Genc B et al.:
A chemoattractant role for NT-3 in proprioceptive axon guidance
PLoS Biol.
2004
2: e403
|
| 21752990 |
Borgesius NZ et al.:
betaCaMKII plays a nonenzymatic role in hippocampal synaptic plasticity and learning by targeting alphaCaMKII to synapses
J. Neurosci.
2011
31
|
| 28607044 |
Sugawara T et al.:
Regulation of spinogenesis in mature Purkinje cells via mGluR/PKC-mediated phosphorylation of CaMKIIbeta
Proc. Natl. Acad. Sci. U.S.A.
2017
114
|
| 11832226 |
Tao X et al.:
A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF
Neuron
2002
33: 383-395
|
| 10964938 |
Pang Z et al.:
Cbln3, a novel member of the precerebellin family that binds specifically to Cbln1
J. Neurosci.
2000
20: 6333-6339
|
| 25818007 |
Winden KD et al.:
Molecular alterations in areas generating fast ripples in an animal model of temporal lobe epilepsy
Neurobiol. Dis.
2015
78: 35-44
|
| 8670833 |
Hugnot JP et al.:
Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels
EMBO J.
1996
15: 3322-3331
|
| 26656649 |
Chong JX et al.:
Gene discovery for Mendelian conditions via social networking: de novo variants in KDM1A cause developmental delay and distinctive facial features
Genet. Med.
2016
18: 788-795
|
| 29670509 |
Vallianatos CN et al.:
Altered Gene-Regulatory Function of KDM5C by a Novel Mutation Associated With Autism and Intellectual Disability
Front Mol Neurosci
2018
11: 104
|
| 17320160 |
Iwase S et al.:
The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases
Cell
2007
128: 1077-1088
|
| 27421841 |
Wei G et al.:
Patient Mutations of the Intellectual Disability Gene KDM5C Downregulate Netrin G2 and Suppress Neurite Growth in Neuro2a Cells
J. Mol. Neurosci.
2016
60: 33-45
|
| 27174676 |
Traunmuller L et al.:
Control of neuronal synapse specification by a highly dedicated alternative splicing program
Science
2016
352: 982-986
|
| 32266715 |
Zhang Z et al.:
A logical relationship for schizophrenia, bipolar, and major depressive disorder. Part 1: Evidence from chromosome 1 high density association screen
|
| 30151950 |
Wojcik MH et al. et al.:
De novo variant in KIF26B is associated with pontocerebellar hypoplasia with infantile spinal muscular atrophy
Am. J. Med. Genet. A
2018
176: 2623-2629
|
| 25464917 |
Wonodi I et al.:
Influence of kynurenine 3-monooxygenase (KMO) gene polymorphism on cognitive function in schizophrenia
Schizophr. Res.
2014
160: 80-87
|
| 31002880 |
Collins BE et al.:
Broad domains of histone 3 lysine 4 trimethylation are associated with transcriptional activation in CA1 neurons of the hippocampus during memory formation
Neurobiol Learn Mem
2019
161: 149-157
|
| 22983954 |
Genin A et al. et al.:
Kinetochore KMN network gene CASC5 mutated in primary microcephaly
Hum. Mol. Genet.
2012
21: 5306-5317
|
| 31392102 |
Yang J et al.:
Integrative analysis of transcriptome-wide association study and gene expression profiling identifies candidate genes associated with stroke
PeerJ
2019
7: e7435
|
| 25124854 |
Zannas AS et al.:
Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age
Am J Psychiatry
2014
171: 1214-1221
|
| 10234025 |
Wright JW et al.:
Contributions of the brain angiotensin IV-AT4 receptor subtype system to spatial learning
J. Neurosci.
1999
19: 3952-3961
|
| 25666589 |
Zhao HR et al.:
Angiotensin II triggers apoptosis via enhancement of NADPH oxidase-dependent oxidative stress in a dopaminergic neuronal cell line
Neurochem. Res.
2015
40: 854-863
|
| 29983322 |
Schroeder A et al.:
A Modular Organization of LRR Protein-Mediated Synaptic Adhesion Defines Synapse Identity
Neuron
2018
99: 329-344.e7
|
| 20519524 |
Siddiqui TJ et al.:
LRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse development
J. Neurosci.
2010
30: 7495-7506
|
| 29863360 |
Siu M et al.:
Dual Leucine Zipper Kinase Inhibitors for the Treatment of Neurodegeneration
J. Med. Chem.
2018
61: 8078-8087
|
| 30056831 |
Koranda JL et al.:
Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning
Neuron
2018
99: 283-292.e5
|
| 31947766 |
Han S et al.:
Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death
|
| 30080045 |
Amberg W et al. et al.:
Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors
J. Med. Chem.
2018
61: 7503-7524
|
| 29430824 |
Sugawara H et al. et al.:
DNA methylation analyses of the candidate genes identified by a methylome-wide association study revealed common epigenetic alterations in schizophrenia and bipolar disorder
Psychiatry Clin. Neurosci.
2018
72: 245-254
|
| 26989944 |
Luigetti M et al.:
Charcot-Marie-Tooth type 2 and distal hereditary motor neuropathy: Clinical, neurophysiological and genetic findings from a single-centre experience
Clin Neurol Neurosurg
2016
144: 67-71
|
| 20800346 |
Shimizu H et al.:
Late-onset CMT2 associated with a novel missense mutation in the cytoplasmic domain of the MPZ gene
Clin Neurol Neurosurg
2010
112: 798-800
|
| 22484440 |
Odagiri S et al.:
Autophagic adapter protein NBR1 is localized in Lewy bodies and glial cytoplasmic inclusions and is involved in aggregate formation in alpha-synucleinopathy
Acta Neuropathol.
2012
124: 173-186
|
| 32053595 |
Singh MD et al. et al.:
NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models
PLoS Genet.
2020
16
|
| 30642278 |
Ling C et al.:
Whole exome sequencing identified a novel truncation mutation in the NHS gene associated with Nance-Horan syndrome
BMC Med. Genet.
2019
20: 14
|
| 15741322 |
Warnecke M et al.:
Abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice impairs the functionality of the forebrain clock and affects nociception
Genes Dev.
2005
19: 614-625
|
| 27772549 |
author information missing
Erratum
J. Invest. Dermatol.
2016
136: 2326
|
| 30796134 |
Soderholm M et al. et al.:
Genome-wide association meta-analysis of functional outcome after ischemic stroke
Neurology
2019
92
|
| 31733190 |
DiStasio A et al.:
Nubp2 is required for cranial neural crest survival in the mouse
Dev. Biol.
2020
458: 189-199
|
| 31022349 |
Boitet ER et al.:
NudC regulates photoreceptor disk morphogenesis and rhodopsin localization
FASEB J.
2019
33: 8799-8808
|
| 21771589 |
Cappello S et al.:
NudC is required for interkinetic nuclear migration and neuronal migration during neocortical development
Dev. Biol.
2011
357: 326-335
|
| 30944919 |
Melis M et al.:
Odor Identification Performance in Idiopathic Parkinsons Disease Is Associated With Gender and the Genetic Variability of the Olfactory Binding Protein
Chem. Senses
2019
44: 311-318
|
| 30659848 |
Maciag F et al.:
Behavioral and electrophysiological changes in female mice overexpressing ORAI1 in neurons
Biochim Biophys Acta Mol Cell Res
2019
1866: 1137-1150
|
| 31009360 |
Secondo A et al.:
ORAI1/STIM1 Interaction Intervenes in Stroke and in Neuroprotection Induced by Ischemic Preconditioning Through Store-Operated Calcium Entry
Stroke
2019
50: 1240-1249
|
| 23918399 |
Anggono V et al.:
PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression
Proc. Natl. Acad. Sci. U.S.A.
2013
110
|
| 23349049 |
Ohtsuka N et al.:
GABAergic neurons regulate lateral ventricular development via transcription factor Pax5
Genesis
2013
51: 234-245
|
| 31092906 |
Feichtinger RG et al. et al.:
Biallelic variants in the transcription factor PAX7 are a new genetic cause of myopathy
Genet. Med.
2019
21: 2521-2531
|
| 23454452 |
Twine NA et al.:
Sequencing of hippocampal and cerebellar transcriptomes provides new insights into the complexity of gene regulation in the human brain
Neurosci. Lett.
2013
541: 263-268
|
| 18568034 |
Su EJ et al. et al.:
Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke
Nat. Med.
2008
14: 731-737
|
| 20231377 |
Tang Z et al. et al.:
Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation
J. Exp. Med.
2010
207: 867-880
|
| 9399911 |
Aral B et al.:
Mutations in PDX1, the human lipoyl-containing component X of the pyruvate dehydrogenase-complex gene on chromosome 11p1, in congenital lactic acidosis
Am. J. Hum. Genet.
1997
61: 1318-1326
|
| 21937992 |
Najmabadi H et al. et al.:
Deep sequencing reveals 50 novel genes for recessive cognitive disorders
Nature
2011
478: 57-63
|
| 20002125 |
Barnerias C et al.:
Pyruvate dehydrogenase complex deficiency: four neurological phenotypes with differing pathogenesis
Dev Med Child Neurol
2010
52: e1-e9
|
| 25222142 |
Lu W et al.:
Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinsons-like movement disorder
Nat Commun
2014
5: 4930
|
| 17609112 |
Kim TH et al.:
Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression
Dev. Cell
2007
13: 87-102
|
| 22215804 |
Sun Z et al.:
A firm grip does not always pay off: a new Phact(r) 4 integrin signaling
Genes Dev.
2012
26: 1-5
|
| 30131250 |
Lu J et al.:
microRNA-124a suppresses PHF19 over-expression, EZH2 hyper-activation, and aberrant cell proliferation in human glioma
Biochem. Biophys. Res. Commun.
2018
503: 1610-1617
|
| 16199551 |
author information missing
Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate
J. Med. Genet.
2005
42: 780-786
|
| 28485378 |
Walsh RM et al. et al.:
Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice
Nat Commun
2017
8: 15142
|
| 29317619 |
Chen X et al. et al.:
Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway
Nat Commun
2018
9: 114
|
| 24670762 |
Lu T et al. et al.:
REST and stress resistance in ageing and Alzheimers disease
Nature
2014
507: 448-454
|
| 26919115 |
Song Z et al.:
REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-beta-catenin signaling
Oncotarget
2016
7
|
| 9620774 |
Semina EV et al.:
A novel homeobox gene PITX3 is mutated in families with autosomal-dominant cataracts and ASMD
Nat. Genet.
1998
19: 167-170
|
| 22223473 |
Derwinska K et al.:
Clinical improvement of the aggressive neurobehavioral phenotype in a patient with a deletion of PITX3 and the absence of L-DOPA in the cerebrospinal fluid
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2012
159B: 236-242
|
| 26049140 |
Zhang J et al.:
A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1(+/-) mice
Neurobiol. Dis.
2015
82: 32-45
|
| 20664637 |
Buchser WJ et al.:
Kinase/phosphatase overexpression reveals pathways regulating hippocampal neuron morphology
Mol. Syst. Biol.
2010
6: 391
|
| 28667723 |
Zahed-Cheikh M et al.:
Kyphoscolitic Type of Ehlers-Danlos Syndrome with Prenatal Stroke
Indian Pediatr
2017
54: 495-497
|
| 12605885 |
Rami A et al.:
Spatial resolution of phospholipid scramblase 1 (PLSCR1), caspase-3 activation and DNA-fragmentation in the human hippocampus after cerebral ischemia
Neurochem. Int.
2003
43: 79-87
|
| 25572966 |
author information missing
Correction for Rietveld et al., Common genetic variants associated with cognitive performance identified using the proxy-phenotype method
Proc. Natl. Acad. Sci. U.S.A.
2015
112: E380
|
| 27428419 |
Ushiama S et al.:
Catecholamines Facilitate Fuel Expenditure and Protect Against Obesity via a Novel Network of the Gut-Brain Axis in Transcription Factor Skn-1-deficient Mice
EBioMedicine
2016
8: 60-71
|
| 15465982 |
Law AJ et al.:
Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: molecular evidence for a pathology of dendritic spines
Am J Psychiatry
2004
161: 1848-1855
|
| 29786422 |
author information missing
Mechanisms Regulating the Association of Protein Phosphatase 1 with Spinophilin and Neurabin
ACS Chem Neurosci
2018
9: 2701-2712
|
| 28700667 |
Wu H et al.:
Age-dependent differential regulation of anxiety- and depression-related behaviors by neurabin and spinophilin
PLoS ONE
2017
12
|
| 25106685 |
Kemeny S et al.:
Clinical and molecular description of a 17q21.33 microduplication in a girl with severe kyphoscoliosis and developmental delay
Eur J Med Genet
2014
57: 552-557
|
| 26934370 |
Hossain MS et al.:
Neuronal Orphan G-Protein Coupled Receptor Proteins Mediate Plasmalogens-Induced Activation of ERK and Akt Signaling
PLoS ONE
2016
11
|
| 31698099 |
Fukuda T et al.:
Exome reports A de novo GNB2 variant associated with global developmental delay, intellectual disability, and dysmorphic features
Eur J Med Genet
2020
63
|
| 18922469 |
Xu Y et al.:
Structure of a protein phosphatase 2A holoenzyme: insights into B55-mediated Tau dephosphorylation
Mol. Cell
2008
31: 873-885
|
| 26005867 |
Chen YC et al. et al.:
Transcriptional regulator PRDM12 is essential for human pain perception
Nat. Genet.
2015
47: 803-808
|
| 32640092 |
Rahman MM et al.:
PR-domain containing protein 12 (prdm12) is a downstream target of transcription factor zic1 during cellular differentiation in central nervous system
|
| 22984654 |
Rosenthal SL et al.:
Beta-amyloid toxicity modifier genes and the risk of Alzheimers disease
Am J Neurodegener Dis
2012
1: 191-198
|
| 32446776 |
Jia E et al.:
Transcriptomic profiling of differentially expressed genes and related pathways in different brain regions in Parkinsons disease
Neurosci. Lett.
2020
732
|
| 27506785 |
Damez-Werno DM et al. et al.:
Histone arginine methylation in cocaine action in the nucleus accumbens
Proc. Natl. Acad. Sci. U.S.A.
2016
113: 9623-9628
|
| 21397065 |
Gal A et al. et al.:
Autosomal-recessive posterior microphthalmos is caused by mutations in PRSS56, a gene encoding a trypsin-like serine protease
Am. J. Hum. Genet.
2011
88: 382-390
|
| 27857231 |
Wang X et al.:
Quantitative proteomic analysis of age-related subventricular zone proteins associated with neurodegenerative disease
Sci Rep
2016
6: 37443
|
| 12099900 |
Tang Y et al.:
Genomic responses of the brain to ischemic stroke, intracerebral haemorrhage, kainate seizures, hypoglycemia, and hypoxia
Eur. J. Neurosci.
2002
15: 1937-1952
|
| 21660509 |
Rehman AU et al. et al.:
Mutations of GIPC3 cause nonsyndromic hearing loss DFNB72 but not DFNB81 that also maps to chromosome 19p
Hum. Genet.
2011
130: 759-765
|
| 21326233 |
Charizopoulou N et al. et al.:
Gipc3 mutations associated with audiogenic seizures and sensorineural hearing loss in mouse and human
Nat Commun
2011
2: 201
|
| 28843862 |
Schneider P et al.:
Altered synaptic phospholipid signaling in PRG-1 deficient mice induces exploratory behavior and motor hyperactivity resembling psychiatric disorders
Behav. Brain Res.
2018
336: 1-7
|
| 31135041 |
Dedek A et al.:
Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing
Brain
2019
142: 1535-1546
|
| 30176350 |
Garcia-Forn M et al.:
Pharmacogenetic modulation of STEP improves motor and cognitive function in a mouse model of Huntingtons disease
Neurobiol. Dis.
2018
120: 88-97
|
| 12932834 |
Skelton MR et al.:
Protein tyrosine phosphatase alpha (PTP alpha) knockout mice show deficits in Morris water maze learning, decreased locomotor activity, and decreases in anxiety
Brain Res.
2003
984: 1-10
|
| 8852383 |
van Inzen WG et al.:
The role of receptor protein tyrosine phosphatase alpha in neuronal differentiation of embryonic stem cells
Brain Res. Dev. Brain Res.
1996
91: 304-307
|
| 28647856 |
Shih Y et al.:
Glial and Neuronal Protein Tyrosine Phosphatase Alpha (PTPalpha) Regulate Oligodendrocyte Differentiation and Myelination
J. Mol. Neurosci.
2017
62: 329-343
|
| 23267136 |
Salehi F et al.:
Immunohistochemical expression of PTTG in brain tumors
Anticancer Res.
2013
33: 119-122
|
| 30640902 |
Waschbusch D et al.:
Rab32 interacts with SNX6 and affects retromer-dependent Golgi trafficking
PLoS ONE
2019
14
|
| 27893846 |
Caetano-Anolles K et al.:
Cerebellum Transcriptome of Mice Bred for High Voluntary Activity Offers Insights into Locomotor Control and Reward-Dependent Behaviors
PLoS ONE
2016
11
|
| 12402263 |
Kure S et al.:
Heterozygous GLDC and GCSH gene mutations in transient neonatal hyperglycinemia
Ann. Neurol.
2002
52: 643-646
|
| 21782286 |
Walter S et al. et al.:
A genome-wide association study of aging
Neurobiol. Aging
2011
32: 2109.e15-2109.e28
|
| 28747427 |
Schwerd T et al. et al.:
A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis
J. Exp. Med.
2017
214: 2547-2562
|
| 27435318 |
Charng WL et al. et al.:
Exome sequencing in mostly consanguineous Arab families with neurologic disease provides a high potential molecular diagnosis rate
BMC Med Genomics
2016
9: 42
|
| 29923028 |
Saeed M et al.:
Genomic convergence of locus-based GWAS meta-analysis identifies AXIN1 as a novel Parkinsons gene
Immunogenetics
2018
70: 563-570
|
| 30210277 |
Logue MW et al.:
Targeted Sequencing of Alzheimer Disease Genes in African Americans Implicates Novel Risk Variants
Front Neurosci
2018
12: 592
|
| 27913681 |
Farrugia AJ et al.:
The Borg family of Cdc42 effector proteins Cdc42EP1-5
Biochem. Soc. Trans.
2016
44: 1709-1716
|
| 28344592 |
Larimore J et al.:
Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus
Front Genet
2017
8: 28
|
| 32469975 |
Maes T et al. et al.:
Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations
PLoS ONE
2020
15
|
| 28993646 |
Christopher MA et al.:
LSD1 protects against hippocampal and cortical neurodegeneration
Nat Commun
2017
8: 805
|
| 22795537 |
Jones WD et al.:
De novo mutations in MLL cause Wiedemann-Steiner syndrome
Am. J. Hum. Genet.
2012
91: 358-364
|
| 27771721 |
Zhang Z et al.:
Leptin Regulates Tau Phosphorylation through Wnt Signaling Pathway in PC12 Cells
Neurosignals
2016
24: 95-101
|
| 31230885 |
Cakici N et al.:
Increased serum levels of leptin and insulin in both schizophrenia and major depressive disorder: A cross-disorder proteomics analysis
Eur Neuropsychopharmacol
2019
29: 835-846
|
| 23471985 |
Jahanshad N et al. et al.:
Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity
Proc. Natl. Acad. Sci. U.S.A.
2013
110: 4768-4773
|
| 30227424 |
author information missing
article information missing
|
| 19666108 |
Beveridge NJ et al.:
Down-regulation of miR-17 family expression in response to retinoic acid induced neuronal differentiation
Cell. Signal.
2009
21: 1837-1845
|
| 17847001 |
Wagenstaller J et al.:
Copy-number variations measured by single-nucleotide-polymorphism oligonucleotide arrays in patients with mental retardation
Am. J. Hum. Genet.
2007
81: 768-779
|
| 31290275 |
Verhoeven W et al.:
A novel MBD5 mutation in an intellectually disabled adult female patient with epilepsy: Suggestive of early onset dementia?
Mol Genet Genomic Med
2019
7: e849
|
| 28965759 |
Yoon KJ et al. et al.:
Temporal Control of Mammalian Cortical Neurogenesis by m(6)A Methylation
Cell
2017
171: 877-889.e17
|
| 16437557 |
Zuchner S et al. et al.:
Axonal neuropathy with optic atrophy is caused by mutations in mitofusin 2
Ann. Neurol.
2006
59: 276-281
|
| 24227656 |
Parkinson W et al.:
N-glycosylation requirements in neuromuscular synaptogenesis
Development
2013
140: 4970-4981
|
| 7506095 |
Hayasaka K et al.:
De novo mutation of the myelin P0 gene in Dejerine-Sottas disease (hereditary motor and sensory neuropathy type III)
Nat. Genet.
1993
5: 266-268
|
| 8816708 |
Warner LE et al. et al.:
Clinical phenotypes of different MPZ (P0) mutations may include Charcot-Marie-Tooth type 1B, Dejerine-Sottas, and congenital hypomyelination
Neuron
1996
17: 451-460
|
| 10553995 |
Plante-Bordeneuve V et al.:
The Roussy-Levy family: from the original description to the gene
Ann. Neurol.
1999
46: 770-773
|
| 21389228 |
Tawk M et al.:
Wnt/beta-catenin signaling is an essential and direct driver of myelin gene expression and myelinogenesis
J. Neurosci.
2011
31: 3729-3742
|
| 31485792 |
Schonkeren SL et al.:
Nervous NDRGs: the N-myc downstream-regulated gene family in the central and peripheral nervous system
Neurogenetics
2019
20: 173-186
|
| 28385010 |
Li G et al.:
Coactosin-like protein 1 inhibits neuronal migration during mouse corticogenesis
J. Vet. Sci.
2018
19: 21-26
|
| 22926577 |
Chen S et al.:
Quantitative proteomic analysis of human substantia nigra in Alzheimers disease, Huntingtons disease and Multiple sclerosis
Neurochem. Res.
2012
37: 2805-2813
|
| 21945734 |
Liu H et al.:
Calcium entry via ORAI1 regulates glioblastoma cell proliferation and apoptosis
Exp. Mol. Pathol.
2011
91: 753-760
|
| 9815975 |
Stuart ET et al.:
PAX5 expression correlates with increasing malignancy in human astrocytomas
Clin. Cancer Res.
1995
1: 207-214
|
| 26464965 |
Oey NE et al.:
A Neuronal Activity-Dependent Dual Function Chromatin-Modifying Complex Regulates Arc Expression }, authors { names std { { name ml Oey NE, affil str Program in Neuroscience and Behavioral Disorders, Duke-NUS Graduate Medical School , Singapore, 169857, Singapore
|
| 29916093 |
Li Q et al.:
Megalin mediates plasma membrane to mitochondria cross-talk and regulates mitochondrial metabolism
Cell. Mol. Life Sci.
2018
75: 4021-4040
|
| 21983856 |
Zhang Z et al.:
Epigenetic suppression of GAD65 expression mediates persistent pain
Nat. Med.
2011
17: 1448-1455
|
| 31272355 |
Rychlik M et al.:
Zinc-mediated Neurotransmission in Alzheimers Disease: A Potential Role of the GPR39 in Dementia
Curr Neuropharmacol
2020
18: 2-13
|
| 30119649 |
Kawazoe T et al. et al.:
Phenotypic variability of Niemann-Pick disease type C including a case with clinically pure schizophrenia: a case report
BMC Neurol
2018
18: 117
|
| 27243477 |
Lin YT et al.:
Chronic activation of NPFFR2 stimulates the stress-related depressive behaviors through HPA axis modulation
Psychoneuroendocrinology
2016
71: 73-85
|
| 28888073 |
Ginsberg SD et al.:
Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimers disease
Hippocampus
2019
29: 422-439
|
| 29371327 |
Inoue N et al. et al.:
Knockdown of the mitochondria-localized protein p13 protects against experimental parkinsonism
|
| 17654705 |
Gimeno L et al.:
Expression of chick Fgf19 and mouse Fgf15 orthologs is regulated in the developing brain by Fgf8 and Shh
Dev Dyn
2007
236: 2285-2297
|
| 30309848 |
Shahin T et al. et al.:
Selective loss of function variants in IL6ST cause Hyper-IgE syndrome with distinct impairments of T-cell phenotype and function
Haematologica
2019
104: 609-621
|
| 28923099 |
Lin H et al.:
Whole blood gene expression and white matter Hyperintensities
Mol Neurodegener
2017
12: 67
|
| 16041373 |
Skibinski G et al. et al.:
Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia
Nat. Genet.
2005
37: 806-808
|
| 30867513 |
Narentuya et al.:
GlcNAc6ST3 is a keratan sulfate sulfotransferase for the protein-tyrosine phosphatase PTPRZ in the adult brain
Sci Rep
2019
9: 4387
|
| 23023331 |
Riazuddin S et al. et al.:
Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48
Nat. Genet.
2012
44: 1265-1271
|
| 18505454 |
Ahmed ZM et al.:
USH1H, a novel locus for type I Usher syndrome, maps to chromosome 15q22-23
Clin. Genet.
2009
75: 86-91
|
| 11486088 |
Liquori CL et al.:
Myotonic dystrophy type 2 caused by a CCTG expansion in intron 1 of ZNF9
Science
2001
293: 864-867
|
| 20335479 |
Wong YH et al.:
Protogenin defines a transition stage during embryonic neurogenesis and prevents precocious neuronal differentiation
J. Neurosci.
2010
30: 4428-4439
|
| 15091340 |
Fernandez-Chacon R et al.:
The synaptic vesicle protein CSP alpha prevents presynaptic degeneration
Neuron
2004
42: 237-251
|
| 25098561 |
Ahmed I et al. et al.:
Identification of a homozygous splice site mutation in the dynein axonemal light chain 4 gene on 22q13.1 in a large consanguineous family from Pakistan with congenital mirror movement disorder
Hum. Genet.
2014
133: 1419-1429
|
| 18579685 |
Tanner CA et al.:
Three members of the LC8/DYNLL family are required for outer arm dynein motor function
Mol. Biol. Cell
2008
19: 3724-3734
|
| 18445593 |
Xu J et al.:
Control of excitatory synaptic transmission by C-terminal Src kinase
J. Biol. Chem.
2008
283
|
| 28501281 |
Wang H et al.:
Alteration of serum adropin level in preeclampsia
Pregnancy Hypertens
2017
8: 6-8
|
| 20716133 |
Mishra M et al.:
The novel protein MANI modulates neurogenesis and neurite-cone growth
J Cell Mol Med
2011
15: 1713-1725
|
| 30760976 |
Jiao Q et al.:
Oxidative Stress Regulated Iron Regulatory Protein IRP2 Through FBXL5-Mediated Ubiquitination-Proteasome Way in SH-SY5Y Cells
Front Neurosci
2019
13: 20
|
| 22344257 |
Kobayashi H et al.:
Rab35 regulates Arf6 activity through centaurin-beta2 (ACAP2) during neurite outgrowth
J Cell Sci
2012
125: 2235-2243
|
| 26435497 |
Ham JE et al.:
Differential expression profiles and roles of inducible DUSPs and ERK1/2-specific constitutive DUSP6 and DUSP7 in microglia
Biochem Biophys Res Commun
2015
467: 254-260
|
| 30214770 |
Shakir A et al.:
The first case of deafness-dystonia syndrome due to compound heterozygous variants in FITM2
Clin Case Rep
2018
6: 1815-1817
|
| 23763432 |
Petersen SL et al.:
Nonclassical progesterone signalling molecules in the nervous system
J Neuroendocrinol
2013
25: 991-1001
|
| 31698102 |
Holtz AM et al.:
Expanding the phenotypic spectrum of Mabry Syndrome with novel PIGO gene variants associated with hyperphosphatasia, intractable epilepsy, and complex gastrointestinal and urogenital malformations
Eur J Med Genet
2020
63
|
| 28366720 |
Schonfeld P et al.:
Brain energy metabolism spurns fatty acids as fuel due to their inherent mitotoxicity and potential capacity to unleash neurodegeneration
Neurochem Int
2017
109: 68-77
|
| 15474354 |
Grothe C et al.:
Fibroblast growth factor-20 promotes the differentiation of Nurr1-overexpressing neural stem cells into tyrosine hydroxylase-positive neurons
Neurobiol Dis
2004
17: 163-170
|
| 29762250 |
author information missing
Abnormal expression of ephrin-A5 affects brain development of congenital hypothyroidism rats
Neuroreport
2018
29: 877-882
|
| 28569795 |
Zou J et al. et al.:
Cystatin C as a potential therapeutic mediator against Parkinsons disease via VEGF-induced angiogenesis and enhanced neuronal autophagy in neurovascular units
Cell Death Dis
2017
8: e2854
|
| 22447935 |
van den Bogaart G et al.:
Phosphatidylinositol 4,5-bisphosphate increases Ca2+ affinity of synaptotagmin-1 by 40-fold
J Biol Chem
2012
287
|
| 22719934 |
Zhang Y et al.:
Deficient dopamine D2 receptor function causes renal inflammation independently of high blood pressure
PLoS One
2012
7
|
| 17380124 |
Lee FJ et al.:
Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor
EMBO J
2007
26: 2127-2136
|
| 21068316 |
Han S et al. et al.:
Regulation of dendritic spines, spatial memory, and embryonic development by the TANC family of PSD-95-interacting proteins
J Neurosci
2010
30
|
| 24014829 |
Xia H et al.:
Brain angiotensin-converting enzyme type 2 shedding contributes to the development of neurogenic hypertension
Circ Res
2013
113: 1087-1096
|
| 31164719 |
Ichihara A et al.:
The (pro)renin receptor in health and disease
Nat Rev Nephrol
2019
15: 693-712
|
| 23595882 |
Korvatska O et al. et al.:
Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS)
Hum Mol Genet
2013
22: 3259-3268
|
| 20093472 |
Cruciat CM et al.:
Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling
Science
2010
327: 459-463
|
| 26329458 |
Henry FE et al.:
Cell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-loss
|
| 29288352 |
Rahimi A et al.:
Sublethal concentration of H2O2 enhances the protective effect of mesenchymal stem cells in rat model of spinal cord injury
Biotechnol Lett
2018
40: 609-615
|
| 18266932 |
Guo S et al.:
Glucose up-regulates HIF-1 alpha expression in primary cortical neurons in response to hypoxia through maintaining cellular redox status
J Neurochem
2008
105: 1849-1860
|
| 15541888 |
Mishra OP et al.:
Effect of hypoxia on the expression and activity of mitogen-activated protein (MAP) kinase-phosphatase-1 (MKP-1) and MKP-3 in neuronal nuclei of newborn piglets: the role of nitric oxide
Neuroscience
2004
129: 665-673
|
| 30252325 |
author information missing
article information missing
|
| 26271746 |
Hackett TA et al.:
Transcriptional maturation of the mouse auditory forebrain
BMC Genomics
2015
16: 606
|
| 27196058 |
Wu X et al.:
Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice
PLoS One
2016
11
|
| 27125467 |
author information missing
Hearing loss, coloboma and left ventricular enlargement in a boy with an interstitial 10q26 deletion
Am J Med Genet C Semin Med Genet
2016
172: 109-116
|
| 12821378 |
Zhang J et al.:
Protein kinase C regulation of glycine and gamma-aminobutyric acid release in brain stem auditory nuclei
Exp Neurol
2003
182: 75-86
|
| 27435822 |
Morris-Blanco KC et al.:
Protein Kinase C Epsilon Promotes Cerebral Ischemic Tolerance Via Modulation of Mitochondrial Sirt5
Sci Rep
2016
6: 29790
|
| 28039372 |
Hickox AE et al.:
Global Analysis of Protein Expression of Inner Ear Hair Cells
J Neurosci
2017
37: 1320-1339
|
| 28414126 |
Luo M et al.:
Characterization of the novel protein KIAA0564 (Von Willebrand Domain-containing Protein 8)
Biochem Biophys Res Commun
2017
487: 545-551
|
| 2542678 |
Konagaya M et al.:
Partial sphingomyelinase deficiency with sea-blue histiocytosis and neurovisceral dysfunction
Jpn J Med
1989
28: 85-88
|
| 22613993 |
Zak M et al.:
Ergic2, a brain specific interacting partner of Otoferlin
Cell Physiol Biochem
2012
29: 941-948
|
| 33160313 |
Lee CH et al.:
Effect of acute noise trauma on the gene expression profile of the hippocampus
BMC Neurosci
2020
21: 45
|
| 27357083 |
Ma Y et al.:
CMPNacetylneuraminic acid synthetase interacts with fragile X related protein 1
Mol Med Rep
2016
14: 1501-1508
|
| 21801852 |
Tsuboi K et al.:
Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways
Biochim Biophys Acta
2011
1811: 565-577
|
| 23575834 |
Subbanna S et al.:
Anandamide-CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits
J Neurosci
2013
33: 6350-6366
|
| 16566017 |
Schiff M et al.:
Leighs disease due to a new mutation in the PDHX gene
Ann Neurol
2006
59: 709-714
|
| 25419155 |
Ruhoy IS et al.:
The genetics of Leigh syndrome and its implications for clinical practice and risk management
Appl Clin Genet
2014
7: 221-234
|
| 17676642 |
Matis C et al.:
Identification of Lmo1 as part of a Hox-dependent regulatory network for hindbrain patterning
Dev Dyn
2007
236: 2675-2684
|
| 6103731 |
author information missing
Glutaminase and aspartate aminotransferase decrease in the cochlear nucleus after lesion of the auditory nerve
Brain Res
1980
190: 293-297
|
| 31071644 |
Hayes SH et al.:
Noise-induced hearing loss alters hippocampal glucocorticoid receptor expression in rats
Hear Res
2019
379: 43-51
|
| 17311311 |
Leake PA et al.:
Neurotrophic effects of GM1 ganglioside and electrical stimulation on cochlear spiral ganglion neurons in cats deafened as neonates
J Comp Neurol
2007
501: 837-853
|
| 33855173 |
Alharby E et al.:
Progressive Ataxia and Neurologic Regression in RFXANK-Associated Bare Lymphocyte Syndrome
Neurol Genet
2021
7: e586
|
| 19641205 |
Wibom R et al.:
AGC1 deficiency associated with global cerebral hypomyelination
N Engl J Med
2009
361: 489-495
|
| 33346119 |
Tran SC et al.:
Effect of Pleomorphic Adenoma Gene 1 Deficiency on Selected Behaviours in Adult Mice
Neuroscience
2021
455: 30-38
|
| 15979591 |
Jaworski DM et al.:
Prepulse inhibition and fear-potentiated startle are altered in tissue inhibitor of metalloproteinase-2 (TIMP-2) knockout mice
Brain Res
2005
1051: 81-89
|
| 19147007 |
Jones C et al.:
Primary cilia in planar cell polarity regulation of the inner ear
Curr Top Dev Biol
2008
85: 197-224
|
| 20798984 |
author information missing
article information missing
|
| 25568106 |
author information missing
article information missing
|
| 33039764 |
author information missing
article information missing
|
| 17196930 |
author information missing
article information missing
|
| 21228163 |
author information missing
article information missing
|
| 33381867 |
author information missing
article information missing
|
| 22730554 |
author information missing
article information missing
|
| 33956893 |
author information missing
article information missing
|
| 33060174 |
author information missing
article information missing
|
| 28297673 |
author information missing
article information missing
|
| 22915120 |
author information missing
article information missing
|
| 31877124 |
author information missing
article information missing
|
| 12467588 |
author information missing
article information missing
|
| 27517863 |
author information missing
article information missing
|
| 14732705 |
author information missing
article information missing
|
| 2241983 |
author information missing
article information missing
|
| 35768207 |
author information missing
article information missing
|
| 32230947 |
author information missing
article information missing
|
| 18511416 |
author information missing
article information missing
|
| 33078695 |
author information missing
article information missing
|
| 16289501 |
author information missing
article information missing
|
| 11157973 |
author information missing
article information missing
|
| 24281389 |
author information missing
article information missing
|
| 9689136 |
author information missing
article information missing
|
| 761642 |
author information missing
article information missing
|
| 288044 |
author information missing
article information missing
|
| 33844597 |
author information missing
article information missing
|
| 10087275 |
author information missing
article information missing
|
| 10618500 |
author information missing
article information missing
|
| 10862698 |
author information missing
article information missing
|
| 12956718 |
author information missing
article information missing
|
| 19793963 |
author information missing
article information missing
|
| 16281028 |
author information missing
article information missing
|
| 24959120 |
author information missing
article information missing
|
| 11459059 |
author information missing
article information missing
|
| 12408866 |
author information missing
article information missing
|
| 17145509 |
author information missing
article information missing
|
| 20141836 |
author information missing
article information missing
|
| 34321660 |
author information missing
article information missing
|
| 17959602 |
author information missing
article information missing
|
| 36309015 |
author information missing
article information missing
|
| 34753794 |
author information missing
article information missing
|
| 18425811 |
author information missing
article information missing
|
| 11929923 |
author information missing
article information missing
|
| 9670010 |
author information missing
article information missing
|
| 9009191 |
author information missing
article information missing
|
| 9620802 |
author information missing
article information missing
|
| 20041218 |
author information missing
article information missing
|
| 16464865 |
author information missing
article information missing
|
| 20220442 |
author information missing
article information missing
|
| 19833157 |
Doi H et al.:
The RNA-binding protein FUS/TLS is a common aggregate-interacting protein in polyglutamine diseases
Neurosci. Res.
2010
66: 131-133
|
| 23028706 |
Meng H et al.:
Biochemical characterization and cellular effects of CADASIL mutants of NOTCH3
PLoS ONE
2012
7
|
| 8136840 |
Koide R et al.:
Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA)
Nat. Genet.
1994
6: 9-13
|
| 30410817 |
Carroll LS et al.:
Dentatorubral-pallidoluysian Atrophy: An Update
Tremor Other Hyperkinet Mov (N Y)
2018
8: 577
|
| 10085113 |
Ellerby LM et al.:
Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity
J. Biol. Chem.
1999
274: 8730-8736
|
| 11575290 |
Fajans SS et al.:
Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young
N. Engl. J. Med.
2001
345: 971-980
|
| 9294105 |
Lindner T et al.:
Hepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 gene
J Clin Invest
1997
100: 1400-1405
|
| 30191603 |
Guo S et al.:
Novel mechanisms of regulation of the expression and transcriptional activity of hepatocyte nuclear factor 4alpha
J Cell Biochem
2019
120: 519-532
|
| 12413008 |
Hara K et al. et al.:
Maturity-onset diabetes of the young resulting from a novel mutation in the HNF-4alpha gene
Intern Med
2002
41: 848-852
|
| 24415854 |
Babeu JP et al.:
Hepatocyte nuclear factor 4-alpha involvement in liver and intestinal inflammatory networks
World J Gastroenterol
2014
20: 22-30
|
| 18356407 |
Harries LW et al.:
The diabetic phenotype in HNF4A mutation carriers is moderated by the expression of HNF4A isoforms from the P1 promoter during fetal development
Diabetes
2008
57: 1745-1752
|
| 31362984 |
Han EH et al.:
ErbB3-binding protein 1 (EBP1) represses HNF4alpha-mediated transcription and insulin secretion in pancreatic beta-cells
J Biol Chem
2019
294
|
| 28364040 |
Sato Y et al.:
Hypoxia reduces HNF4alpha/MODY1 protein expression in pancreatic beta-cells by activating AMP-activated protein kinase
J Biol Chem
2017
292: 8716-8728
|
| 29850377 |
Vadakedath S et al.:
Probable Potential Role of Urate Transporter Genes in the Development of Metabolic Disorders
Cureus
2018
10: e2382
|
| 16731834 |
Sagen JV et al. et al.:
From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation
Diabetes
2006
55: 1713-1722
|
| 19864570 |
Spencer B et al.:
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinsons and Lewy body diseases
J. Neurosci.
2009
29
|
| 19864570 |
Spencer B et al.:
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinsons and Lewy body diseases
J. Neurosci.
2009
29
|
| 14675537 |
Kawaguchi Y et al.:
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
Cell
2003
6: 727-738
|
| 12000718 |
Schlossmacher MG et al.:
Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies.
Am. J. Pathol.
2002
160: 1655-1667
|
| 15845543 |
Shin Y et al.:
The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways.
J. Biol. Chem.
2005
280
|
| 15791003 |
Zhang W et al.:
Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinsons disease
FASEB J.
2005
19: 533-542
|
| 16672220 |
Ko HS et al.:
Identification of far upstream element-binding protein-1 as an authentic Parkin substrate
J. Biol. Chem.
2006
281
|
| 19298851 |
Navarro A et al.:
Human brain cortex: mitochondrial oxidative damage and adaptive response in Parkinson disease and in dementia with Lewy bodies
Free Radic. Biol. Med.
2009
46: 1574-1580
|
| 31547145 |
van Steenoven I et al.:
VGF Peptides in Cerebrospinal Fluid of Patients with Dementia with Lewy Bodies
|
| 21232013 |
Stergiakouli E et al.:
Steroid sulfatase is a potential modifier of cognition in Attention Deficit Hyperactivity Disorder
|
| 18180757 |
Guan L et al.:
A high-density single-nucleotide polymorphism screen of 23 candidate genes in attention deficit hyperactivity disorder: suggesting multiple susceptibility genes among Chinese Han population
Mol. Psychiatry
2009
14: 546-554
|
| 22981920 |
Weissflog L et al.:
KCNIP4 as a candidate gene for personality disorders and adult ADHD
Eur Neuropsychopharmacol
2013
6: 436-447
|
| 21832240 |
Lionel AC et al.:
Rare copy number variation discovery and cross-disorder comparisons identify risk genes for ADHD
Sci Transl Med
2011
3: 95RA75
|
| 30976917 |
Wang M et al.:
STX1A gene variations contribute to the susceptibility of children attention-deficit/hyperactivity disorder: a case-control association study
|
| 22420048 |
Williams NM et al. et al.:
Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3
Am J Psychiatry
2012
169: 195-204
|
| 20887894 |
Feng M et al.:
Store-independent activation of Orai1 by SPCA2 in mammary tumors
Cell
2010
143: 84-98
|
| 32075770 |
Salesse C et al.:
Opposite Control of Excitatory and Inhibitory Synapse Formation by Slitrk2 and Slitrk5 on Dopamine Neurons Modulates Hyperactivity Behavior
Cell Rep
2020
30: 2374-2386.e5
|
| 24350812 |
Johnson KA et al.:
Methylphenidate side effect profile is influenced by genetic variation in the attention-deficit/hyperactivity disorder-associated CES1 gene
J Child Adolesc Psychopharmacol
2013
23: 655-664
|
| 31835028 |
author information missing
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Cell
2019
179: 1469-1482.e11
|
| 22425645 |
Soufi M et al.:
The impact of severe LDL receptor mutations on SREBP-pathway regulation in homozygous familial hypercholesterolemia (FH)
Gene
2012
499: 218-222
|
| 29874871 |
Benito-Vicente A et al.:
Validation of LDLr Activity as a Tool to Improve Genetic Diagnosis of Familial Hypercholesterolemia: A Retrospective on Functional Characterization of LDLr Variants
|
| 14961121 |
Tian XL et al.:
Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome
Nature
2004
427: 640-645
|
| 21326321 |
Zhang Y et al.:
Two missense variants in UHRF1BP1 are independently associated with systemic lupus erythematosus in Hong Kong Chinese
Genes Immun.
2011
12: 231-234
|
| 25912736 |
Dong G et al.:
17beta-Estradiol enhances the activation of IFN-alpha signaling in B cells by down-regulating the expression of let-7e-5p, miR-98-5p and miR-145a-5p that target IKKepsilon
Biochim. Biophys. Acta
2015
1852: 1585-1598
|
| 28062664 |
Odhams CA et al.:
Mapping eQTLs with RNA-seq reveals novel susceptibility genes, non-coding RNAs and alternative-splicing events in systemic lupus erythematosus
Hum. Mol. Genet.
2017
26: 1003-1017
|
| 18240231 |
Pullmann R Jr et al.:
Haplotypes of the HRES-1 endogenous retrovirus are associated with development and disease manifestations of systemic lupus erythematosus
Arthritis Rheum.
2008
58: 532-540
|
| 30154210 |
Nag S et al.:
Rab4A organizes endosomal domains for sorting cargo to lysosome-related organelles
|
| 30154210 |
Nag S et al.:
Rab4A organizes endosomal domains for sorting cargo to lysosome-related organelles
|
| 31346090 |
Li Y et al. et al.:
TMEM203 is a binding partner and regulator of STING-mediated inflammatory signaling in macrophages
Proc. Natl. Acad. Sci. U.S.A.
2019
116
|
| 31563273 |
Montufar-Robles I et al.:
The AIRE Ser196Ser synonymous variant is a risk factor for systemic lupus erythematosus
Cell. Immunol.
2019
346
|
| 32240818 |
Liao J et al.:
Overexpression of CXCR5 in CD4(+) T cells of SLE patients caused by excessive SETD3
Clin. Immunol.
2020
214
|
| 27399966 |
author information missing
article information missing
|
| 34127828 |
author information missing
article information missing
|
| 21629437 |
author information missing
article information missing
|
| 27813531 |
author information missing
article information missing
|
| 17311901 |
author information missing
article information missing
|
| 25500879 |
author information missing
article information missing
|
| 33076992 |
author information missing
article information missing
|
| 25205108 |
author information missing
article information missing
|
| 14657503 |
Ebralidze A et al.:
RNA leaching of transcription factors disrupts transcription in myotonic dystrophy
Science
2004
303: 383-387
|
| 31010208 |
Voellenkle C et al. et al.:
Dysregulation of Circular RNAs in Myotonic Dystrophy Type 1
|
| 17702266 |
Tanaka S et al.:
Identification of differentially expressed genes in blood cells of narcolepsy patients
Sleep
2007
30: 974-979
|
| 26859814 |
den Braber A et al.:
Obsessive-compulsive symptoms in a large population-based twin-family sample are predicted by clinically based polygenic scores and by genome-wide SNPs
Transl Psychiatry
2016
6: e731
|
| 18216249 |
Gatchel JR et al.:
The insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 1291-1296
|
| 27466200 |
Sanchez I et al.:
Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3beta-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1)
Hum. Mol. Genet.
2016
25: 4021-4040
|
| 25403488 |
Li C et al.:
MicroRNA 648 Targets ET-1 mRNA and is cotranscriptionally regulated with MICAL3 by PAX5
Mol. Cell. Biol.
2015
35: 514-528
|
| 22385522 |
Ratnayake M et al.:
Allelic expression analysis of the osteoarthritis susceptibility locus that maps to MICAL3
BMC Med. Genet.
2012
13: 12
|
| 22298781 |
Rhee J et al.:
alpha-Catenin inhibits beta-catenin-T-cell factor/lymphoid enhancing factor transcriptional activity and collagen type II expression in articular chondrocytes through formation of Gli3R.alpha-catenin.beta-catenin ternary complex
J. Biol. Chem.
2012
287
|
| 26767374 |
Li Y et al.:
Alterations of amino acid metabolism in osteoarthritis: its implications for nutrition and health
Amino Acids
2016
48: 907-914
|
| 24758933 |
Liu L et al.:
Protective effect of resveratrol against IL-1beta-induced inflammatory response on human osteoarthritic chondrocytes partly via the TLR4/MyD88/NF-kappaB signaling pathway: an in vitro study
Int J Mol Sci
2014
15: 6925-6940
|
| 19635554 |
Surridge AK et al.:
Characterization and regulation of ADAMTS-16
Matrix Biol.
2009
28: 416-424
|
| 28274888 |
Han J et al.:
Altered expression of chondroitin sulfate structure modifying sulfotransferases in the articular cartilage from adult osteoarthritis and Kashin-Beck disease
Osteoarthr. Cartil.
2017
25: 1372-1375
|
| 30664745 |
Tachmazidou I et al. et al.:
Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data
Nat Genet
2019
51: 230-236
|
| 10611355 |
An J et al.:
Estradiol repression of tumor necrosis factor-alpha transcription requires estrogen receptor activation function-2 and is enhanced by coactivators.
Proc. Natl. Acad. Sci. U.S.A.
1999
96
|
| 21060993 |
Hong D et al.:
Quantitative proteomic analysis of dexamethasone-induced effects on osteoblast differentiation, proliferation, and apoptosis in MC3T3-E1 cells using SILAC
Osteoporos Int
2011
22: 2175-2186
|
| 19657144 |
Almeida M et al.:
Increased lipid oxidation causes oxidative stress, increased peroxisome proliferator-activated receptor-gamma expression, and diminished pro-osteogenic Wnt signaling in the skeleton
J. Biol. Chem.
2009
284
|
| 30834083 |
Cai L et al.:
Gene co-expression network analysis identifies BRCC3 as a key regulator in osteogenic differentiation of osteoblasts through a beta-catenin signaling dependent pathway
Iran J Basic Med Sci
2019
22: 173-178
|
| 30150596 |
Rivera-Paredez B et al. et al.:
Association between Vitamin D Deficiency and Single Nucleotide Polymorphisms in the Vitamin D Receptor and GC Genes and Analysis of Their Distribution in Mexican Postmenopausal Women
|
| 31744088 |
Fujimori K et al.:
Synthesis of Novel Farnesoid X Receptor Agonists and Validation of Their Efficacy in Activating Differentiation of Mouse Bone Marrow-Derived Mesenchymal Stem Cells into Osteoblasts
|
| 29435145 |
Zuo C et al.:
TNF-alpha inhibits SATB2 expression and osteoblast differentiation through NF-kappaB and MAPK pathways
Oncotarget
2017
9: 4833-4850
|
| 26435169 |
Zhang L et al. et al.:
Network-based proteomic analysis for postmenopausal osteoporosis in Caucasian females
Proteomics
2016
16: 12-28
|
| 9487134 |
Cuppen E et al.:
PDZ motifs in PTP-BL and RIL bind to internal protein segments in the LIM domain protein RIL
Mol Biol Cell
1998
9: 671-683
|
| 33177505 |
Tan JH et al. et al.:
EMC6 regulates acinar apoptosis via APAF1 in acute and chronic pancreatitis
Cell Death Dis
2020
11: 966
|
| 25880754 |
Ye H et al.:
CD4 T-cell transcriptome analysis reveals aberrant regulation of STAT3 and Wnt signaling pathways in rheumatoid arthritis: evidence from a case-control study
Arthritis Res. Ther.
2015
17: 76
|
| 23328930 |
Tian J et al.:
Resveratrol inhibits TNF-alpha-induced IL-1beta, MMP-3 production in human rheumatoid arthritis fibroblast-like synoviocytes via modulation of PI3kinase/Akt pathway
Rheumatol. Int.
2013
33: 1829-1835
|
| 25697137 |
Filkova M et al.:
Pro-inflammatory effects of interleukin-35 in rheumatoid arthritis
Cytokine
2015
73: 36-43
|
| 14608356 |
Tokuhiro S et al. et al.:
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis
Nat Genet
2003
35: 341-348
|
| 17287217 |
author information missing
article information missing
|
| 24127308 |
author information missing
article information missing
|
| 36300114 |
author information missing
article information missing
|
| 28188247 |
author information missing
article information missing
|
| 35256696 |
author information missing
article information missing
|
| 35776431 |
author information missing
article information missing
|
| 37667923 |
author information missing
article information missing
|
| 34195267 |
author information missing
article information missing
|
| 19753663 |
Koefoed P et al.:
An intron 1 polymorphism in the cholecystokinin-A receptor gene associated with schizophrenia in males
Acta Psychiatr Scand
2009
120: 281-287
|
| 19405953 |
Martins-de-Souza D et al.:
Proteome analysis of schizophrenia patients Wernickes area reveals an energy metabolism dysregulation.
BMC Psychiatry
2009
9: 17
|
| 19588471 |
Seeman P et al.:
Glutamate agonist LY404,039 for treating schizophrenia has affinity for the dopamine D2(High) receptor.
Synapse
2009
63: 935-939
|
| 19393294 |
Bertolino A et al.:
The genetics of schizophrenia
Neuroscience
2009
164: 288-299
|
| 17948905 |
Giegling I et al.:
Dopa decarboxylase and tyrosine hydroxylase gene variants in suicidal behavior
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2008
147: 308-315
|
| 11673800 |
Borglum AD et al.:
Dopa decarboxylase genotypes may influence age at onset of schizophrenia.
Mol. Psychiatry
2001
6: 712-717
|
| 12150646 |
Albert KA et al.:
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
Arch. Gen. Psychiatry
2002
59: 705-712
|
| 18829695 |
Bertolino A et al.:
Functional variants of the dopamine receptor D2 gene modulate prefronto-striatal phenotypes in schizophrenia
Brain
2009
132: 417-425
|
| 19049562 |
Liou YJ et al.:
The coding-synonymous polymorphism rs1045280 (Ser280Ser) in beta-arrestin 2 (ARRB2) gene is associated with tardive dyskinesia in Chinese patients with schizophrenia
Eur. J. Neurol.
2008
15: 1406-1408
|
| 17825267 |
Thiselton DL et al.:
AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families.
Biol. Psychiatry
2008
63: 449-457
|
| 16959423 |
Joo EJ et al.:
The dysbindin gene (DTNBP1) and schizophrenia: no support for an association in the Korean population
Neurosci. Lett.
2006
407: 101-106
|
| 19800201 |
Riley B et al.:
The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample
Schizophr. Res.
2009
115: 245-253
|
| 19835666 |
Ganzinelli S et al.:
Autoantibodies from schizophrenia patients induce cerebral cox-1/iNOS mRNA expression with NO/PGE2/MMP-3 production
Int. J. Neuropsychopharmacol.
2010
13: 293-303
|
| 19829704 |
Oyagi A et al.:
Generation and characterization of conditional heparin-binding EGF-like growth factor knockout mice
PLoS ONE
2009
4: E7461
|
| 19746410 |
Vares M et al.:
Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2010
153B: 610-618
|
| 18988738 |
Roffman JL et al.:
MTHFR 677C --> T genotype disrupts prefrontal function in schizophrenia through an interaction with COMT 158Val --> Met
Proc. Natl. Acad. Sci. U.S.A.
2008
105
|
| 19564051 |
Feng LG et al.:
Association of plasma homocysteine and methylenetetrahydrofolate reductase C677T gene variant with schizophrenia: A Chinese Han population-based case-control study
Psychiatry Res
2009
168: 205-208
|
| 16641680 |
Lee YS et al.:
Serum homocysteine, folate level and methylenetetrahydrofolate reductase 677, 1298 gene polymorphism in Korean schizophrenic patients
Neuroreport
2006
17: 743-746
|
| 16969279 |
Philibert R et al.:
No association of the C677T methylenetetrahydrofolate reductase polymorphism with schizophrenia
Psychiatr. Genet.
2006
16: 221-223
|
| 19268435 |
Brisch R et al.:
Dopamine-glutamate abnormalities in the frontal cortex associated with the catechol-O-methyltransferase (COMT) in schizophrenia.
Brain Res.
2009
1269: 166-175
|
| 19329282 |
Okochi T et al.:
Meta-analysis of association between genetic variants in COMT and schizophrenia: an update
Schizophr. Res.
2009
110: 140-148
|
| 18834502 |
Stefanis NC et al.:
Association of RGS4 variants with schizotypy and cognitive endophenotypes at the population level
Behav Brain Funct
2008
4: 46
|
| 17220354 |
Gu Z et al.:
RGS4 modulates serotonin signaling in prefrontal cortex and links to serotonin dysfunction in a rat model of schizophrenia.
Mol. Pharmacol.
2007
71: 1030-1039
|
| 17275115 |
Watanabe Y et al.:
No association between the ERBB3 gene and schizophrenia in a Japanese population.
Neurosci. Res.
2007
57: 574-578
|
| 15334603 |
Aston C et al.:
Microarray analysis of postmortem temporal cortex from patients with schizophrenia.
J. Neurosci. Res.
2004
77: 858-866
|
| 17696993 |
Koh HY et al.:
Deficits in social behavior and sensorimotor gating in mice lacking phospholipase Cbeta1.
Genes Brain Behav.
2008
7: 120-128
|
| 16402134 |
Mah S et al.:
Identification of the semaphorin receptor PLXNA2 as a candidate for susceptibility to schizophrenia.
Mol. Psychiatry
2006
11: 471-478
|
| 18096369 |
Budel S et al.:
No association between schizophrenia and polymorphisms of the PlexinA2 gene in Chinese Han Trios.
Schizophr. Res.
2008
99: 365-366
|
| 12610647 |
Eastwood SL et al.:
The axonal chemorepellant semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology.
Mol. Psychiatry
2003
8: 148-155
|
| 16513881 |
Eastwood SL et al.:
Cellular basis of reduced cortical reelin expression in schizophrenia
Am J Psychiatry
2006
163: 540-542
|
| 19430527 |
Campo CG et al.:
Reelin secreted by GABAergic neurons regulates glutamate receptor homeostasis.
PLoS ONE
2009
4: E5505
|
| 15961543 |
Grayson DR et al.:
Reelin promoter hypermethylation in schizophrenia.
Proc. Natl. Acad. Sci. U.S.A.
2005
102: 9341-9346
|
| 19937158 |
Numata S et al.:
Association study between the pericentrin (PCNT) gene and schizophrenia
Neuromolecular Med.
2010
12: 243-247
|
| 19913623 |
Mata I et al.:
Additive effect of NRG1 and DISC1 genes on lateral ventricle enlargement in first episode schizophrenia
Neuroimage
2010
53: 1016-1022
|
| 10814723 |
Millar JK et al.:
Disruption of two novel genes by a translocation co-segregating with schizophrenia.
Hum. Mol. Genet.
2000
9: 1415-1423
|
| 6087160 |
Bibb JA et al.:
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.
Nature
1999
402: 669-671
|
| 10884434 |
Abi-Dargham A et al.:
Increased baseline occupancy of D2 receptors by dopamine in schizophrenia.
Proc. Natl. Acad. Sci. U.S.A.
2000
97: 8104-8109
|
| 7865171 |
Okada F et al.:
Reduced concentrations of the alpha-subunit of GTP-binding protein Go in schizophrenic brain.
J. Neural Transm. Gen. Sect.
1994
95: 95-104
|
| 11978847 |
Abi-Dargham A et al.:
Prefrontal dopamine D1 receptors and working memory in schizophrenia.
J. Neurosci.
2002
22: 3708-3719
|
| 16946930 |
Abi-Dargham A et al.:
Probing cortical dopamine function in schizophrenia: what can D1 receptors tell us
World Psychiatry
2003
2: 166-171
|
| 9024661 |
Okubo Y et al.:
Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET.
Nature
1997
385: 634-636
|
| 9503283 |
Dean B et al.:
Changes in protein kinase C and adenylate cyclase in the temporal lobe from subjects with schizophrenia.
J Neural Transm
1997
104: 1371-1381
|
| 16406317 |
Minoretti P et al.:
The T393C polymorphism of the GNAS1 gene is associated with deficit schizophrenia in an Italian population sample.
Neurosci. Lett.
2006
397: 159-163
|
| 17681085 |
Amar S et al.:
Possible involvement of post-dopamine D2 receptor signalling components in the pathophysiology of schizophrenia.
Int. J. Neuropsychopharmacol.
2008
11: 197-205
|
| 11215760 |
Jensen JB et al.:
Abnormal protein phosphorylation in post-mortem brain tissue from bipolar patients.
J Neural Transm
2000
107: 501-509
|
| 10882848 |
Tardito D et al.:
Abnormal levels of cAMP-dependent protein kinase regulatory subunits in platelets from schizophrenic patients.
Neuropsychopharmacology
2000
23: 216-219
|
| 19796684 |
Logue SF et al.:
The orphan GPCR, GPR88, modulates function of the striatal dopamine system: a possible therapeutic target for psychiatric disorders?
Mol. Cell. Neurosci.
2009
42: 438-447
|
| 19538708 |
Tanda K et al.:
Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminergic signaling in neuronal nitric oxide synthase knockout mice.
Mol Brain
2009
2: 19
|
| 18573638 |
Feldcamp LA et al.:
Reduced prefrontal cortex DARPP-32 mRNA in completed suicide victims with schizophrenia.
Schizophr. Res.
2008
103: 192-200
|
| 16483723 |
Xie Z et al.:
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase.
Neuroscience
2006
139: 597-607
|
| 18998737 |
Siuciak JA et al.:
The role of phosphodiesterases in schizophrenia : therapeutic implications
CNS Drugs
2008
22: 983-993
|
| 19661377 |
Grauer SM et al.:
Phosphodiesterase 10A inhibitor activity in preclinical models of the positive, cognitive, and negative symptoms of schizophrenia.
J. Pharmacol. Exp. Ther.
2009
331: 574-590
|
| 6087160 |
Hemmings HC Jr et al.:
DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1.
Nature
1984
310: 503-505
|
| 17618027 |
Hu JX et al.:
An association study between PPP1R1B gene and schizophrenia in the Chinese population.
Prog. Neuropsychopharmacol. Biol. Psychiatry
2007
31: 1303-1306
|
| 17684498 |
Wiedholz LM et al.:
Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and schizophrenia-related behaviors
Mol. Psychiatry
2008
13: 631-640
|
| 14678778 |
Galter D et al.:
ALDH1 mRNA: presence in human dopamine neurons and decreases in substantia nigra in Parkinsons disease and in the ventral tegmental area in schizophrenia
Neurobiol. Dis.
2003
14: 637-647
|
| 14744247 |
Svenningsson P et al.:
DARPP-32: an integrator of neurotransmission.
Annu. Rev. Pharmacol. Toxicol.
2004
44: 269-296
|
| 20185149 |
Athanasiu L et al.:
Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
J Psychiatr Res
2010
44: 748-753
|
| 20161799 |
Domenici E et al.:
Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections.
PLoS ONE
2010
5: E9166
|
| 20071346 |
Ingason A et al.:
A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia
Hum. Mol. Genet.
2010
19: 1379-1386
|
| 19412172 |
Huffaker SJ et al.:
A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia.
Nat. Med.
2009
15: 509-518
|
| 19794330 |
Schuhmacher A et al.:
Influence of 5-HT3 receptor subunit genes HTR3A, HTR3B, HTR3C, HTR3D and HTR3E on treatment response to antipsychotics in schizophrenia
Pharmacogenet. Genomics
2009
19: 843-851
|
| 19805695 |
Donohoe G et al.:
Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects
Arch. Gen. Psychiatry
2009
66: 1045-1054
|
| 18945720 |
Rujescu D et al. et al.:
Disruption of the neurexin 1 gene is associated with schizophrenia
Hum. Mol. Genet.
2009
18: 988-996
|
| 18849890 |
Mossner R et al.:
Functional serotonin 1A receptor variant influences treatment response to atypical antipsychotics in schizophrenia.
Pharmacogenet. Genomics
2009
19: 91-94
|
| 18614340 |
Mossner R et al.:
Further evidence for a functional role of the glutamate receptor gene GRM3 in schizophrenia.
Eur Neuropsychopharmacol
2008
18: 768-772
|
| 15522253 |
Yamada K et al.:
Association analysis of FEZ1 variants with schizophrenia in Japanese cohorts.
Biol. Psychiatry
2004
56: 683-690
|
| 15992519 |
Verma R et al.:
MLC1 gene is associated with schizophrenia and bipolar disorder in Southern India
Biol. Psychiatry
2005
58: 16-22
|
| 12506198 |
Ozeki Y et al.:
Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth
Proc Natl Acad Sci U S A
2003
100: 289-294
|
| 12364586 |
Chumakov I et al.:
Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia.
Proc. Natl. Acad. Sci. U.S.A.
2002
99
|
| 20417696 |
Kantrowitz JT et al.:
N-methyl-d-aspartate (NMDA) receptor dysfunction or dysregulation: the final common pathway on the road to schizophrenia
Brain Res. Bull.
2010
83: 108-121
|
| 15841096 |
Qin S et al.:
An association study of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA microarray
Eur. J. Hum. Genet.
2005
13: 807-814
|
| 19856012 |
Schmitt A et al.:
Gene expression of NMDA receptor subunits in the cerebellum of elderly patients with schizophrenia
Eur Arch Psychiatry Clin Neurosci
2010
260: 101-111
|
| 20113358 |
Benedetti F et al.:
Temporal lobe grey matter volume in schizophrenia is associated with a genetic polymorphism influencing glycogen synthase kinase 3-beta activity
Genes Brain Behav.
2010
9: 365-371
|
| 19303846 |
Mao Y et al.:
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling.
Cell
2009
136: 1017-1031
|
| 9631433 |
Cotter D et al.:
Abnormalities of Wnt signalling in schizophrenia--evidence for neurodevelopmental abnormality.
Neuroreport
1998
9: 1379-1383
|
| 17324475 |
Lovestone S et al.:
Schizophrenia as a GSK-3 dysregulation disorder.
Trends Neurosci.
2007
30: 142-149
|
| 16293762 |
Millar JK et al.:
DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling.
Science
2005
310: 1187-1191
|
| 14745448 |
Emamian ES et al.:
Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia
Nat. Genet.
2004
36: 131-137
|
| 14745448 |
Emamian ES et al.:
Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia.
Nat. Genet.
2004
36: 131-137
|
| 18497887 |
Tan HY et al.:
Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans
J. Clin. Invest.
2008
118: 2200-2208
|
| 20570110 |
Muller N et al.:
Celecoxib treatment in an early stage of schizophrenia: results of a randomized, double-blind, placebo-controlled trial of celecoxib augmentation of amisulpride treatment
Schizophr. Res.
2010
121: 118-124
|
| 20553865 |
Ellman LM et al.:
Structural brain alterations in schizophrenia following fetal exposure to the inflammatory cytokine interleukin-8
Schizophr. Res.
2010
121: 46-54
|
| 20510460 |
Chang SH et al.:
Expression of anti-cardiolipin antibodies and inflammatory associated factors in patients with schizophrenia
Psychiatry Res
2011
187: 341-346
|
| 19058794 |
Song XQ et al.:
The interaction of nuclear factor-kappa B and cytokines is associated with schizophrenia.
Biol. Psychiatry
2009
65: 481-488
|
| 17822540 |
Saetre P et al.:
Inflammation-related genes up-regulated in schizophrenia brains
BMC Psychiatry
2007
7: 46
|
| 18005941 |
Potvin S et al.:
Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review
Biol. Psychiatry
2008
63: 801-808
|
| 19007319 |
Muller N et al.:
Inflammation and the glutamate system in schizophrenia: implications for therapeutic targets and drug development
Expert Opin. Ther. Targets
2008
12: 1497-1507
|
| 20147364 |
Wonodi I et al.:
Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in Schizophrenia
Schizophr Bull
2010
36: 211-218
|
| 19139851 |
Zhang XY et al.:
Superoxide dismutase and cytokines in chronic patients with schizophrenia: association with psychopathology and response to antipsychotics
Psychopharmacology (Berl.)
2009
204: 177-184
|
| 17030375 |
Miyaoka T et al.:
Possible antipsychotic effects of minocycline in patients with schizophrenia
Prog. Neuropsychopharmacol. Biol. Psychiatry
2007
31: 304-307
|
| 18301953 |
Mizuno M et al.:
The anthraquinone derivative Emodin ameliorates neurobehavioral deficits of a rodent model for schizophrenia
J Neural Transm
2008
115: 521-530
|
| 20637820 |
Cai HL et al.:
Elevated plasma gamma-aminobutyrate/glutamate ratio and responses to risperidone antipsychotic treatment in schizophrenia
Prog. Neuropsychopharmacol. Biol. Psychiatry
2010
34: 1273-1278
|
| 20492850 |
Laan W et al.:
Adjuvant aspirin therapy reduces symptoms of schizophrenia spectrum disorders: results from a randomized, double-blind, placebo-controlled trial
J Clin Psychiatry
2010
71: 520-527
|
| 20417248 |
Knuesel I et al.:
Reelin-mediated signaling in neuropsychiatric and neurodegenerative diseases
Prog. Neurobiol.
2010
91: 257-274
|
| 17936586 |
Suzuki K et al.:
Decreased expression of reelin receptor VLDLR in peripheral lymphocytes of drug-naive schizophrenic patients
Schizophr. Res.
2008
98: 148-156
|
| 20673161 |
Martins-de-Souza D et al.:
The role of energy metabolism dysfunction and oxidative stress in schizophrenia revealed by proteomics
Antioxid. Redox Signal.
2011
15: 2067-2079
|
| 20673164 |
Chowdari KV et al.:
Genetic association studies of antioxidant pathway genes and schizophrenia
Antioxid. Redox Signal.
2011
15: 2037-2045
|
| 18778695 |
Narayan S et al.:
Molecular profiles of schizophrenia in the CNS at different stages of illness
Brain Res.
2008
1239: 235-248
|
| 12679240 |
Begni S et al.:
Association between the G1001C polymorphism in the GRIN1 gene promoter region and schizophrenia
Biol. Psychiatry
2003
53: 617-619
|
| 16899352 |
Passos Gregorio S et al.:
Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects
Schizophr. Res.
2006
88: 275-282
|
| 18281018 |
Yang MS et al.:
Chitinase-3-like 1 (CHI3L1) gene and schizophrenia: genetic association and a potential functional mechanism
Biol. Psychiatry
2008
64: 98-103
|
| 16223876 |
Glatt SJ et al.:
Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia
Proc. Natl. Acad. Sci. U.S.A.
2005
102
|
| 19702693 |
Blanc O et al.:
Pharmacogenetic of response efficacy to antipsychotics in schizophrenia: pharmacodynamic aspects. Review and implications for clinical research
Fundam Clin Pharmacol
2010
24: 139-160
|
| 18972444 |
Wang YD et al.:
Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response
Hepatology
2008
48: 1632-1643
|
| 15698673 |
Rioux L et al.:
The expression of retinoic acid receptor alpha is increased in the granule cells of the dentate gyrus in schizophrenia
Psychiatry Res
2005
133: 13-21
|
| 15838536 |
Goodman AB et al.:
Microarray results suggest altered transport and lowered synthesis of retinoic acid in schizophrenia
Mol. Psychiatry
2005
10: 620-621
|
| 12812986 |
Morris JA et al.:
DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation
Hum. Mol. Genet.
2003
12: 1591-1608
|
| 17043677 |
Camargo LM et al.:
Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia
Mol Psychiatry
2007
12: 74-86
|
| 19191256 |
Anitha A et al.:
Association studies and gene expression analyses of the DISC1-interacting molecules, pericentrin 2 (PCNT2) and DISC1-binding zinc finger protein (DBZ), with schizophrenia and with bipolar disorder
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2009
150B: 967-976
|
| 20880836 |
Park YU et al.:
Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 11278159 |
Maurer I et al.:
Evidence for a mitochondrial oxidative phosphorylation defect in brains from patients with schizophrenia
Schizophr. Res.
2001
48: 125-136
|
| 21123035 |
Bubber P et al.:
Abnormalities in the tricarboxylic acid (TCA) cycle in the brains of schizophrenia patients
Eur Neuropsychopharmacol
2011
21: 254-260
|
| 20833242 |
Clay HB et al.:
Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia
Int. J. Dev. Neurosci.
2011
29: 311-324
|
| 20980130 |
Verge B et al.:
Mitochondrial DNA (mtDNA) and schizophrenia
Eur. Psychiatry
2011
26: 45-56
|
| 21183010 |
Moreau MP et al.:
Altered microRNA expression profiles in postmortem brain samples from individuals with schizophrenia and bipolar disorder
Biol. Psychiatry
2011
69: 188-193
|
| 20381070 |
Martins-de-Souza D et al.:
Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia
J Psychiatr Res
2010
44: 989-991
|
| 15098003 |
Prabakaran S et al.:
Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress.
Mol. Psychiatry
2004
9: 684-697
|
| 21346763 |
Vacic V et al.:
Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia
Nature
2011
471: 499-503
|
| 21397211 |
Rosenfeld M et al.:
Perturbation in mitochondrial network dynamics and in complex I dependent cellular respiration in schizophrenia
Biol. Psychiatry
2011
69: 980-988
|
| 21421043 |
Weigelt K et al.:
TREM-1 and DAP12 expression in monocytes of patients with severe psychiatric disorders. EGR3, ATF3 and PU.1 as important transcription factors
Brain Behav. Immun.
2011
25: 1162-1169
|
| 10980328 |
Tanaka KF et al.:
Serum interleukin-18 levels are elevated in schizophrenia.
Psychiatry Res
2000
96: 75-80
|
| 8998275 |
Maes M et al.:
Lower plasma CC16, a natural anti-inflammatory protein, and increased plasma interleukin-1 receptor antagonist in schizophrenia: effects of antipsychotic drugs.
Schizophr. Res.
1996
21: 39-50
|
| 12566931 |
Nikkila HV et al.:
Neopterin and macrophage inflammatory protein-1alpha in the cerebrospinal fluid of schizophrenic patients: no evidence of intrathecal inflammation.
Neuropsychobiology
2002
46: 169-172
|
| 14623370 |
Schwab SG et al.:
Association of tumor necrosis factor alpha gene -G308A polymorphism with schizophrenia.
Schizophr. Res.
2003
65: 19-25
|
| 15549344 |
Muller N et al.:
Clinical effects of COX-2 inhibitors on cognition in schizophrenia
Eur Arch Psychiatry Clin Neurosci
2005
255: 149-151
|
| 21429189 |
Oresic M et al.:
Metabolome in schizophrenia and other psychotic disorders: a general population-based study
Genome Med
2011
3: 19
|
| 21747397 |
Rietschel M et al.:
Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe
Mol. Psychiatry
2012
17: 906-917
|
| 21543597 |
Quednow BB et al.:
The schizophrenia risk allele C of the TCF4 rs9960767 polymorphism disrupts sensorimotor gating in schizophrenia spectrum and healthy volunteers
J. Neurosci.
2011
31: 6684-6691
|
| 21349497 |
Zhang F et al.:
Evidence of sex-modulated association of ZNF804A with schizophrenia.
Biol. Psychiatry
2011
69: 914-917
|
| 21228604 |
Lennertz L et al.:
Novel schizophrenia risk gene TCF4 influences verbal learning and memory functioning in schizophrenia patients
Neuropsychobiology
2011
63: 131-136
|
| 15044694 |
Beaulieu JM et al.:
Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade.
Proc. Natl. Acad. Sci. U.S.A.
2004
101: 5099-5104
|
| 11873706 |
Seeman P et al.:
Atypical antipsychotics: mechanism of action.
Can J Psychiatry
2002
47: 27-38
|
| 20520744 |
Schwarz E et al.:
Validation of a blood-based laboratory test to aid in the confirmation of a diagnosis of schizophrenia
Biomark Insights
2010
5: 39-47
|
| 21936766 |
Hashimoto R et al.:
The KCNH2 gene is associated with neurocognition and the risk of schizophrenia
World J. Biol. Psychiatry
2013
14: 114-120
|
| 18521091 |
Volpi S et al.:
Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia
Mol. Psychiatry
2009
14: 1024-1031
|
| 17001352 |
Dettling M et al.:
Clozapine-induced agranulocytosis in schizophrenic Caucasians: confirming clues for associations with human leukocyte class I and II antigens
Pharmacogenomics J.
2007
7: 325-332
|
| 9713902 |
Arinami T et al.:
Evidence supporting an association between the DRB1 gene and schizophrenia in Japanese
Schizophr. Res.
1998
32: 81-86
|
| 23423139 |
Scarr E et al.:
Decreased cortical muscarinic M1 receptors in schizophrenia are associated with changes in gene promoter methylation, mRNA and gene targeting microRNA
Transl Psychiatry
2013
3: E230
|
| 10227113 |
Bymaster FP et al.:
Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and alpha 1-adrenergic receptors in vitro
Schizophr. Res.
1999
37: 107-122
|
| 22695490 |
Deng C et al.:
Reducing olanzapine-induced weight gain side effect by using betahistine: a study in the rat model
J. Psychopharmacol. (Oxford)
2012
26: 1271-1279
|
| 18358632 |
Han M et al.:
Short- and long-term effects of antipsychotic drug treatment on weight gain and H1 receptor expression
Psychoneuroendocrinology
2008
33: 569-580
|
| 23640535 |
He M et al.:
The role of hypothalamic H1 receptor antagonism in antipsychotic-induced weight gain
CNS Drugs
2013
27: 423-434
|
| 17360666 |
Kim SF et al.:
From the Cover: Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase
Proc. Natl. Acad. Sci. U.S.A.
2007
104: 3456-3459
|
| 11901361 |
Ellingrod VL et al.:
CYP2D6 polymorphisms and atypical antipsychotic weight gain
Psychiatr. Genet.
2002
12: 55-58
|
| 23277265 |
Tiwari AK et al.:
Association of a functional polymorphism in neuropeptide Y with antipsychotic-induced weight gain in schizophrenia patients
J Clin Psychopharmacol
2013
33: 11-17
|
| 20631561 |
Monteleone P et al.:
Endocannabinoid Pro129Thr FAAH functional polymorphism but not 1359G/A CNR1 polymorphism is associated with antipsychotic-induced weight gain
J Clin Psychopharmacol
2010
30: 441-445
|
| 17804136 |
Kang SG et al.:
Possible association between the -2548A/G polymorphism of the leptin gene and olanzapine-induced weight gain
Prog. Neuropsychopharmacol. Biol. Psychiatry
2008
32: 160-163
|
| 19521639 |
Lim C et al.:
Psychosocial factors in the neurobiology of schizophrenia: a selective review
Ann. Acad. Med. Singap.
2009
38: 402-406
|
| 21971780 |
Kunz M et al.:
Serum levels of IL-6, IL-10 and TNF-alpha in patients with bipolar disorder and schizophrenia: differences in pro- and anti-inflammatory balance
Rev Bras Psiquiatr
2011
33: 268-274
|
| 22425530 |
Ratliff JC et al.:
The effect of dietary and physical activity pattern on metabolic profile in individuals with schizophrenia: a cross-sectional study
Compr Psychiatry
2012
53: 1028-1033
|
| 2307007 |
Bradley TD et al.:
Differential activation of respiratory muscles by CO2 and hypoxia in man
Chest
1990
97: 52S
|
| 23132271 |
Roussos P et al.:
Convergent findings for abnormalities of the NF-kappaB signaling pathway in schizophrenia
Neuropsychopharmacology
2013
38: 533-539
|
| 23706954 |
Kim SK et al.:
A polymorphism (rs4773092, Cys816Cys) of IRS2 affects auditory hallucinations in schizophrenia patients
Psychiatry Res
2013
209: 124-125
|
| 12363386 |
Xing G et al.:
Decreased calcium-dependent constitutive nitric oxide synthase (cNOS) activity in prefrontal cortex in schizophrenia and depression
Schizophr. Res.
2002
58: 21-30
|
| 22920733 |
Costa M et al.:
Investigation of endocannabinoid system genes suggests association between peroxisome proliferator activator receptor-alpha gene (PPARA) and schizophrenia
Eur Neuropsychopharmacol
2013
23: 749-759
|
| 20923924 |
Bradley AJ et al.:
A systematic review of hypothalamic-pituitary-adrenal axis function in schizophrenia: implications for mortality
J. Psychopharmacol. (Oxford)
2010
24: 91-118
|
| 15949648 |
de Leon J et al.:
A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors
Schizophr. Res.
2005
76: 135-157
|
| 21549182 |
Ritsner MS et al.:
The clinical and therapeutic potentials of dehydroepiandrosterone and pregnenolone in schizophrenia
Neuroscience
2011
191: 91-100
|
| 20375926 |
Hong CJ et al.:
Dopamine receptor D2 gene is associated with weight gain in schizophrenic patients under long-term atypical antipsychotic treatment
Pharmacogenet. Genomics
2010
20: 359-366
|
| 19441803 |
Ji B et al.:
A comparative proteomics analysis of rat mitochondria from the cerebral cortex and hippocampus in response to antipsychotic medications
J. Proteome Res.
2009
8: 3633-3641
|
| 22689948 |
Law AJ et al.:
Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110delta inhibition as a potential therapeutic strategy
Proc. Natl. Acad. Sci. U.S.A.
2012
109
|
| 21418140 |
Hong LE et al.:
A CHRNA5 allele related to nicotine addiction and schizophrenia
Genes Brain Behav.
2011
10: 530-535
|
| 20393456 |
Petrovsky N et al.:
Sensorimotor gating is associated with CHRNA3 polymorphisms in schizophrenia and healthy volunteers
Neuropsychopharmacology
2010
35: 1429-1439
|
| 18762859 |
Kishi T et al.:
Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population
J Neural Transm
2008
115: 1457-1461
|
| 17008057 |
Jurata LW et al.:
Altered expression of hippocampal dentate granule neuron genes in a mouse model of human 22q11 deletion syndrome
Schizophr. Res.
2006
88: 251-259
|
| 24113126 |
Ota VK et al.:
Neurotransmitter receptor and regulatory gene expression in peripheral blood of Brazilian drug-naive first-episode psychosis patients before and after antipsychotic treatment
Psychiatry Res
2013
210: 1290-1292
|
| 21926974 |
Schizophrenia Psychiatric Genome-Wide Association
Study (GWAS) Consortium et al.:
Genome-wide association study identifies five new schizophrenia loci
Nat. Genet.
2011
43: 969-976
|
| 24319118 |
Andreassen OA et al.:
Boosting the power of schizophrenia genetics by leveraging new statistical tools
Schizophr Bull
2014
40: 13-17
|
| 24355530 |
Zheng F et al.:
Further evidence for genetic association of CACNA1C and schizophrenia: new risk loci in a Han Chinese population and a meta-analysis
Schizophr. Res.
2014
152: 105-110
|
| 24166486 |
Sleiman P et al.:
GWAS meta analysis identifies TSNARE1 as a novel Schizophrenia / Bipolar susceptibility locus
Sci Rep
2013
3: 3075
|
| 19483194 |
Labrie V et al.:
Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model
Hum. Mol. Genet.
2009
18: 3227-3243
|
| 19197363 |
Need AC et al.:
A genome-wide investigation of SNPs and CNVs in schizophrenia
PLoS Genet.
2009
5
|
| 22832956 |
Wirgenes KV et al.:
TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders
Transl Psychiatry
2012
2: E112
|
| 18426314 |
Behravan J et al.:
Linkage and association of DRD2 gene TaqI polymorphism with schizophrenia in an Iranian population
Arch Iran Med
2008
11: 252-256
|
| 24463508 |
Purcell SM et al.:
A polygenic burden of rare disruptive mutations in schizophrenia
Nature
2014
506: 185-190
|
| 22892715 |
He Y et al.:
Schizophrenia shows a unique metabolomics signature in plasma
Transl Psychiatry
2012
2: E149
|
| 23637704 |
Wright C et al.:
Potential Impact of miR-137 and Its Targets in Schizophrenia
Front Genet
2013
4: 58
|
| 22384243 |
Girgenti MJ et al.:
ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2
PLoS ONE
2012
7
|
| 24566148 |
Yin J et al.:
miR-137: a new player in schizophrenia
Int J Mol Sci
2014
15: 3262-3271
|
| 115032 |
et al.:
Reduction of MOPEG levels in cerebrospinal fluid of psychotic women after electroconvulsive treatment
Psychopharmacology (Berl.)
1979
64: 131-134
|
| 2480613 |
author information missing
article information missing
|
| 23462049 |
Matosin N et al.:
Metabotropic glutamate receptor 5 binding and protein expression in schizophrenia and following antipsychotic drug treatment
Schizophr. Res.
2013
146: 170-176
|
| 24462263 |
Guella I et al.:
Allelic imbalance associated with the schizophrenia risk SNP rs1344706 indicates a cis-acting variant in ZNF804A
Schizophr. Res.
2014
153: 243-245
|
| 21521618 |
Matta JA et al.:
mGluR5 and NMDA receptors drive the experience- and activity-dependent NMDA receptor NR2B to NR2A subunit switch
Neuron
2011
70: 339-351
|
| 22883350 |
Kim AH et al.:
Experimental validation of candidate schizophrenia gene ZNF804A as target for hsa-miR-137
Schizophr. Res.
2012
141: 60-64
|
| 24275578 |
Guan F et al.:
MIR137 gene and target gene CACNA1C of miR-137 contribute to schizophrenia susceptibility in Han Chinese
Schizophr. Res.
2014
152: 97-104
|
| 24556472 |
Hill MJ et al.:
Transcriptional consequences of schizophrenia candidate miR-137 manipulation in human neural progenitor cells
Schizophr. Res.
2014
153: 225-230
|
| 24024939 |
Newell KA et al.:
Metabotropic glutamate receptor 5 in schizophrenia: emerging evidence for the development of antipsychotic drugs
Future Med Chem
2013
5: 1471-1474
|
| 23001156 |
Sokoloff P et al.:
Direct and indirect interactions of the dopamine D(3) receptor with glutamate pathways: implications for the treatment of schizophrenia
Naunyn Schmiedebergs Arch. Pharmacol.
2013
386: 107-124
|
| 21943960 |
Pereira A et al.:
Clozapine induction of ERK1/2 cell signalling via the EGF receptor in mouse prefrontal cortex and striatum is distinct from other antipsychotic drugs
Int. J. Neuropsychopharmacol.
2012
15: 1149-1160
|
| 23142770 |
Pereira A et al.:
Clozapine regulation of p90RSK and c-Fos signaling via the ErbB1-ERK pathway is distinct from olanzapine and haloperidol in mouse cortex and striatum
Prog. Neuropsychopharmacol. Biol. Psychiatry
2013
40: 353-363
|
| 23540600 |
Pinacho R et al.:
Analysis of Sp transcription factors in the postmortem brain of chronic schizophrenia: a pilot study of relationship to negative symptoms
J Psychiatr Res
2013
47: 926-934
|
| 22832524 |
Braunewell KH et al.:
Association of VSNL1 with schizophrenia, frontal cortical function, and biological significance for its gene product as a modulator of cAMP levels and neuronal morphology
Transl Psychiatry
2011
1: E22
|
| 11930147 |
Bernstein HG et al.:
Hippocampal expression of the calcium sensor protein visinin-like protein-1 in schizophrenia
Neuroreport
2002
13: 393-396
|
| 22781170 |
Carty NC et al.:
The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications
Transl Psychiatry
2012
2: e137
|
| 21239144 |
Dow DJ et al.:
ADAMTSL3 as a candidate gene for schizophrenia: gene sequencing and ultra-high density association analysis by imputation
Schizophr. Res.
2011
127: 28-34
|
| 23551272 |
Heinrich A et al.:
From gene to brain to behavior: schizophrenia-associated variation in AMBRA1 alters impulsivity-related traits
Eur. J. Neurosci.
2013
38: 2941-2945
|
| 23894747 |
Aberg KA et al.:
A comprehensive family-based replication study of schizophrenia genes
JAMA Psychiatry
2013
70: 573-581
|
| 21439553 |
Havik B et al.:
The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia
Biol. Psychiatry
2011
70: 35-42
|
| 23490763 |
Scarr E et al.:
Cholinergic muscarinic M4 receptor gene polymorphisms: a potential risk factor and pharmacogenomic marker for schizophrenia
Schizophr. Res.
2013
146: 279-284
|
| 23272693 |
Foster DJ et al.:
Emerging approaches for treatment of schizophrenia: modulation of cholinergic signaling
Discov Med
2012
14: 413-420
|
| 24984191 |
Collins AL et al.:
Transcriptional targets of the schizophrenia risk gene MIR137
Transl Psychiatry
2014
4: E404
|
| 24866554 |
Valles A et al.:
MicroRNA-137 regulates a glucocorticoid receptor-dependent signalling network: implications for the etiology of schizophrenia
J Psychiatry Neurosci
2014
39
|
| 22182936 |
et al.:
Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets
Mol. Psychiatry
2013
18: 11-12
|
| 12796220 |
Hashimoto K et al.:
Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia
Arch. Gen. Psychiatry
2003
60: 572-576
|
| 24413739 |
Quednow BB et al.:
Transcription factor 4 (TCF4) and schizophrenia: integrating the animal and the human perspective
Cell. Mol. Life Sci.
2014
71: 2815-2835
|
| 18936756 |
Le Hellard S et al.:
Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples
Mol. Psychiatry
2010
15: 463-472
|
| 24329191 |
Vassas TJ et al.:
Pharmacogenomics of sterol synthesis and statin use in schizophrenia subjects treated with antipsychotics
Pharmacogenomics
2014
15: 61-67
|
| 15877707 |
Dragovic M et al.:
Handedness in schizophrenia: a quantitative review of evidence
Acta Psychiatr Scand
2005
111: 410-419
|
| 20457675 |
Loe-Mie Y et al.:
SMARCA2 and other genome-wide supported schizophrenia-associated genes: regulation by REST/NRSF, network organization and primate-specific evolution
Hum. Mol. Genet.
2010
19: 2841-2857
|
| 18347602 |
Sullivan PF et al.:
Genomewide association for schizophrenia in the CATIE study: results of stage 1
Mol. Psychiatry
2008
13: 570-584
|
| 25056061 |
author information missing
Biological insights from 108 schizophrenia-associated genetic loci
Nature
2014
511: 421-427
|
| 26404636 |
Brzozka MM et al.:
Tcf4 transgenic female mice display delayed adaptation in an auditory latent inhibition paradigm
|
| 23129290 |
Navarrete K et al.:
TCF4 (e2-2; ITF2): a schizophrenia-associated gene with pleiotropic effects on human disease
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2013
162B: 1-16
|
| 25445625 |
Kebir O et al.:
Family-based association study of common variants, rare mutation study and epistatic interaction detection in HDAC genes in schizophrenia
Schizophr. Res.
2014
160: 97-103
|
| 19571811 |
Purcell SM et al.:
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
Nature
2009
460: 748-752
|
| 25048004 |
Focking M et al.:
Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia
Mol. Psychiatry
2015
20: 424-432
|
| 25522406 |
Crespo-Facorro B et al.:
Schizophrenia gene expression profile reverted to normal levels by antipsychotics
|
| 25205248 |
Gampe K et al.:
NTPDase2 and purinergic signaling control progenitor cell proliferation in neurogenic niches of the adult mouse brain
Stem Cells
2015
33: 253-264
|
| 20537721 |
Saito A et al.:
An association study on polymorphisms in the PEA15, ENTPD4, and GAS2L1 genes and schizophrenia
Psychiatry Res
2011
185: 9-15
|
| 27069920 |
Wu CC et al.:
Antipsychotic Drugs Inhibit Platelet Aggregation via P2Y 1 and P2Y 12 Receptors
Biomed Res Int
2016
2016
|
| 30579835 |
Ramos-Miguel A et al.:
Reduced SNAP25 Protein Fragmentation Contributes to SNARE Complex Dysregulation in Schizophrenia Postmortem Brain
|
| 20598862 |
Dresner E et al.:
Activity-dependent neuroprotective protein (ADNP) expression level is correlated with the expression of the sister protein ADNP2: deregulation in schizophrenia
Eur Neuropsychopharmacol
2011
21: 355-361
|
| 17961987 |
Sharma RP et al.:
Histone deactylase 1 expression is increased in the prefrontal cortex of schizophrenia subjects: analysis of the National Brain Databank microarray collection
Schizophr. Res.
2008
98: 111-117
|
| 30726206 |
Cera I et al.:
Genes encoding SATB2-interacting proteins in adult cerebral cortex contribute to human cognitive ability
PLoS Genet.
2019
15
|
| 30040823 |
Whitton L et al.:
Genes regulated by SATB2 during neurodevelopment contribute to schizophrenia and educational attainment
PLoS Genet.
2018
14
|
| 31078689 |
Gilabert-Juan J et al.:
Time dependent expression of the blood biomarkers EIF2D and TOX in patients with schizophrenia
|
| 23153507 |
Supriyanto I et al. et al.:
A missense mutation in the ITGA8 gene, a cell adhesion molecule gene, is associated with schizophrenia in Japanese female patients
Prog. Neuropsychopharmacol. Biol. Psychiatry
2013
40: 347-352
|
| 21743468 |
Girard SL et al. et al.:
Increased exonic de novo mutation rate in individuals with schizophrenia
Nat. Genet.
2011
43: 860-863
|
| 30381832 |
Tang J et al.:
A logical relationship for schizophrenia, bipolar, and major depressive disorder. Part 4: Evidence from chromosome 4 high-density association screen
J Comp Neurol
2019
527: 392-405
|
| 14732590 |
Porton B et al.:
A rare polymorphism affects a mitogen-activated protein kinase site in synapsin III: possible relationship to schizophrenia
Biol. Psychiatry
2004
55: 118-125
|
| 11867627 |
Yang LT et al.:
c-SRC mediates neurite outgrowth through recruitment of Crk to the scaffolding protein Sin/Efs without altering the kinetics of ERK activation
J. Biol. Chem.
2002
277
|
| 25347937 |
Pidsley R et al.:
Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia
Genome Biol.
2014
15: 483
|
| 26232077 |
Saia-Cereda VM et al.:
Proteomics of the corpus callosum unravel pivotal players in the dysfunction of cell signaling, structure, and myelination in schizophrenia brains
Eur Arch Psychiatry Clin Neurosci
2015
265: 601-612
|
| 19255580 |
Maycox PR et al. et al.:
Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function
Mol. Psychiatry
2009
14: 1083-1094
|
| 19508883 |
Mas S et al.:
ARVCF single marker and haplotypic association with schizophrenia
Prog. Neuropsychopharmacol. Biol. Psychiatry
2009
33: 1064-1069
|
| 26460480 |
Ingason A et al. et al.:
Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case-control sample of schizophrenia
Transl Psychiatry
2015
5: e656
|
| 26968334 |
Zhou D et al.:
15q13.3 duplication in two patients with childhood-onset schizophrenia
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2016
171: 777-783
|
| 21970977 |
Stephens SH et al.:
Multiple genes in the 15q13-q14 chromosomal region are associated with schizophrenia
Psychiatr. Genet.
2012
22: 1-14
|
| 21531385 |
Liu CM et al. et al.:
ANXA7, PPP3CB, DNAJC9, and ZMYND17 genes at chromosome 10q22 associated with the subgroup of schizophrenia with deficits in attention and executive function
Biol. Psychiatry
2011
70: 51-58
|
| 16783572 |
Shifman S et al.:
A complete genetic association scan of the 22q11 deletion region and functional evidence reveal an association between DGCR2 and schizophrenia
Hum. Genet.
2006
120: 160-170
|
| 28011714 |
Viana J et al.:
Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions
Hum. Mol. Genet.
2017
26: 210-225
|
| 24365867 |
Merenlender-Wagner A et al.:
Autophagy has a key role in the pathophysiology of schizophrenia
Mol. Psychiatry
2015
20: 126-132
|
| 28230289 |
Ishimoto T et al.:
Mice lacking BCAS1, a novel myelin-associated protein, display hypomyelination, schizophrenia-like abnormal behaviors, and upregulation of inflammatory genes in the brain
Glia
2017
65: 727-739
|
| 29065368 |
Lee H et al.:
BBOX1 is down-regulated in maternal immune-activated mice and implicated in genetic susceptibility to human schizophrenia
Psychiatry Res
2018
259: 197-202
|
| 19913919 |
Yuan P et al.:
Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia
J Affect Disord
2010
124: 164-169
|
| 30368554 |
Albert-Gasco H et al.:
Central relaxin-3 receptor (RXFP3) activation impairs social recognition and modulates ERK-phosphorylation in specific GABAergic amygdala neurons
Brain Struct Funct
2019
224: 453-469
|
| 23053966 |
Kang WS et al.:
Genetic variants of GRIA1 are associated with susceptibility to schizophrenia in Korean population
Mol. Biol. Rep.
2012
39
|
| 31162297 |
Zhou J et al. et al.:
Common variants in SATB2 are associated with schizophrenia in Uygur Chinese population
Psychiatr. Genet.
2019
29: 120-126
|
| 18203698 |
Morris HM et al.:
Alterations in somatostatin mRNA expression in the dorsolateral prefrontal cortex of subjects with schizophrenia or schizoaffective disorder
Cereb. Cortex
2008
18: 1575-1587
|
| 24552634 |
Bulbul F et al.:
New molecule in the etiology of schizophrenia: urotensin II
Psychiatry Clin. Neurosci.
2014
68: 133-136
|
| 18572318 |
Ono T et al.:
Urotensin II evokes neurotransmitter release from rat cerebrocortical slices
Neurosci. Lett.
2008
440: 275-279
|
| 26508570 |
Ambalavanan A et al. et al.:
De novo variants in sporadic cases of childhood onset schizophrenia
Eur. J. Hum. Genet.
2016
24: 944-948
|
| 20570600 |
Bergman O et al.:
Preliminary evidence that polymorphisms in dopamine-related transcription factors LMX1A, LMX1B and PITX3 are associated with schizophrenia
Prog. Neuropsychopharmacol. Biol. Psychiatry
2010
34: 1094-1097
|
| 20385374 |
Ide M et al.:
Altered cortical CDC42 signaling pathways in schizophrenia: implications for dendritic spine deficits
Biol. Psychiatry
2010
68: 25-32
|
| 30285260 |
Ikeda M et al. et al.:
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect
Schizophr Bull
2019
45: 824-834
|
| 22555153 |
Pelov I et al.:
Involvement of PTPN5, the gene encoding the striatal-enriched protein tyrosine phosphatase, in schizophrenia and cognition
Psychiatr. Genet.
2012
22: 168-176
|
| 30594456 |
John J et al.:
Rare variants in Protein tyrosine phosphatase, receptor type A (PTPRA) in schizophrenia: Evidence from a family based study
Schizophr. Res.
2019
206: 75-81
|
| 31840934 |
Guan F et al.:
Evaluation of the relationships of the WBP1L gene with schizophrenia and the general psychopathology scale based on a case-control study
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2020
183: 164-171
|
| 32180374 |
Zhang H et al.:
Fine-mapping of ZDHHC2 identifies risk variants for schizophrenia in the Han Chinese population
Mol Genet Genomic Med
2020
8: e1190
|
| 29024729 |
Zhao Y et al. et al.:
Integrating genome-wide association study and expression quantitative trait locus study identifies multiple genes and gene sets associated with schizophrenia
Prog. Neuropsychopharmacol. Biol. Psychiatry
2018
81: 50-54
|
| 26736035 |
Xu Y et al.:
Potential involvement of the interleukin-18 pathway in schizophrenia
J Psychiatr Res
2016
74: 10-16
|
| 17667961 |
Francks C et al. et al.:
LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia
Mol. Psychiatry
2007
12: 1129-1139
|
| 31165892 |
Chan RF et al.:
Independent Methylome-Wide Association Studies of Schizophrenia Detect Consistent Case-Control Differences
Schizophr Bull
2020
46: 319-327
|
| 26674772 |
Zhang Z et al.:
Evidence for Association of Cell Adhesion Molecules Pathway and NLGN1 Polymorphisms with Schizophrenia in Chinese Han Population
PLoS ONE
2015
10
|
| 23805179 |
Hass J et al. et al.:
A Genome-Wide Association Study Suggests Novel Loci Associated with a Schizophrenia-Related Brain-Based Phenotype
PLoS ONE
2013
8
|
| 26546129 |
Jurczyk A et al. et al.:
Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic beta-cell function via glycogen synthase kinase-3beta
FASEB J.
2016
30: 983-993
|
| 28117656 |
Lee SA et al.:
Epigenetic profiling of human brain differential DNA methylation networks in schizophrenia
BMC Med Genomics
2016
9: 68
|
| 23904455 |
Sanders AR et al.:
Transcriptome study of differential expression in schizophrenia
Hum Mol Genet
2013
22: 5001-5014
|
| 29496332 |
Kim P et al.:
Abnormal expression of ER quality control and ER associated degradation proteins in the dorsolateral prefrontal cortex in schizophrenia
Schizophr Res
2018
197: 484-491
|
| 29483656 |
Pardinas AF et al. et al.:
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Nat Genet
2018
50: 381-389
|
| 26198764 |
Goes FS et al. et al.:
Genome-wide association study of schizophrenia in Ashkenazi Jews
Am J Med Genet B Neuropsychiatr Genet
2015
168: 649-659
|
| 20507645 |
author information missing
article information missing
|
| 26879421 |
author information missing
article information missing
|
| 31570775 |
author information missing
article information missing
|
| 26246156 |
author information missing
article information missing
|
| 33758079 |
author information missing
article information missing
|
| 23999525 |
Turner JR et al.:
Evidence from mouse and man for a role of neuregulin 3 in nicotine dependence
|
| 21498873 |
Keskitalo-Vuokko K et al.:
Associations of nicotine intake measures with CHRN genes in Finnish smokers
Nicotine Tob. Res.
2011
13: 686-690
|
| 19268276 |
Vink JM et al.:
Genome-wide association study of smoking initiation and current smoking
Am. J. Hum. Genet.
2009
84: 367-379
|
| 18519826 |
Uhl GR et al.:
Molecular genetics of successful smoking cessation: convergent genome-wide association study results
Arch. Gen. Psychiatry
2008
65: 683-693
|
| 23312075 |
Tuohey L et al.:
PLAC4 is upregulated in severe early onset preeclampsia and upregulated with syncytialisation but not hypoxia
Placenta
2013
34: 256-260
|
| 25052193 |
Ling KH et al. et al.:
Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks
BMC Genomics
2014
15: 624
|
| 18541381 |
Moldrich RX et al.:
Transmembrane protein 50b (C21orf4), a candidate for Down syndrome neurophenotypes, encodes an intracellular membrane protein expressed in the rodent brain
Neuroscience
2008
154: 1255-1266
|
| 17950572 |
Lockstone HE et al.:
Gene expression profiling in the adult Down syndrome brain
Genomics
2007
90: 647-660
|
| 21856934 |
Lima FA et al.:
Decreased AIRE expression and global thymic hypofunction in Down syndrome
J. Immunol.
2011
187: 3422-3430
|
| 15716609 |
Chung IH et al.:
Gene expression analysis of cultured amniotic fluid cell with Down syndrome by DNA microarray
J Korean Med Sci
2005
20: 82-87
|
| 21942715 |
Lai Y et al.:
Proteomic dissection of the von Hippel-Lindau (VHL) interactome
J. Proteome Res.
2011
10: 5175-5182
|
| 21972040 |
Huang Y et al.:
Germline mutations of the VHL gene in seven Chinese families with von Hippel-Lindau disease
Int. J. Mol. Med.
2012
29: 47-52
|
| 22964440 |
Tsang JP et al.:
Arginase deficiency with new phenotype and a novel mutation: contemporary summary
Pediatr. Neurol.
2012
47: 263-269
|
| 24166829 |
Balmer C et al.:
Mutations and polymorphisms in the human argininosuccinate lyase (ASL) gene
Hum. Mutat.
2014
35: 27-35
|
| 7078580 |
author information missing
Treatment of inborn errors of urea synthesis: activation of alternative pathways of waste nitrogen synthesis and excretion
N. Engl. J. Med.
1982
306: 1387-1392
|
| 24508627 |
Woo HI et al.:
Molecular genetics of citrullinemia types I and II
Clin. Chim. Acta
2014
431: 1-8
|
| 23073314 |
Kolbe EW et al.:
CLCA4 variants determine the manifestation of the cystic fibrosis basic defect in the intestine
Eur. J. Hum. Genet.
2013
21: 691-694
|
| 25599739 |
Koulivand L et al.:
Cystinuria in a Patient With a Novel Mutation in SLC7A9 Gene
Iran J Kidney Dis
2015
9: 63-66
|
| 19008341 |
Lee JH et al.:
Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway
Diabetes
2009
58: 344-351
|
| 19008341 |
Lee JH et al.:
Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway.
Diabetes
2009
58: 344-351
|
| 15152190 |
Yeung F et al.:
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
EMBO J.
2004
23: 2369-2380
|
| 16551748 |
Eldor R et al.:
Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents
Proc. Natl. Acad. Sci. U.S.A.
2006
103: 5072-5077
|
| 19133311 |
Manna P et al.:
Protective role of arjunolic acid in response to streptozotocin-induced type-I diabetes via the mitochondrial dependent and independent pathways.
Toxicology
2009
257: 53-63
|
| 19071154 |
Song MY et al.:
Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway.
Toxicol. Appl. Pharmacol.
2009
235: 57-67
|
| 17521952 |
Kim EK et al.:
Activation of peroxisome proliferator-activated receptor-gamma protects pancreatic beta-cells from cytokine-induced cytotoxicity via NF kappaB pathway.
Int. J. Biochem. Cell Biol.
2007
39: 1260-1275
|
| 15096655 |
Lgssiar A et al.:
Interleukin-11 inhibits NF-kappaB and AP-1 activation in islets and prevents diabetes induced with streptozotocin in mice
Exp. Biol. Med. (Maywood)
2004
229: 425-436
|
| 12776270 |
Makita Y et al.:
Methylenetetrahydrofolate reductase gene polymorphism and susceptibility to diabetic nephropathy in type 1 diabetes
Am. J. Kidney Dis.
2003
41: 1189-1194
|
| 22563461 |
Asad S et al.:
HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13
PLoS ONE
2012
7
|
| 3519679 |
Tessari P et al.:
Defective suppression by insulin of leucine-carbon appearance and oxidation in type 1, insulin-dependent diabetes mellitus. Evidence for insulin resistance involving glucose and amino acid metabolism
J. Clin. Invest.
1986
77: 1797-1804
|
| 20379810 |
Flamez D et al.:
A genomic-based approach identifies FXYD domain containing ion transport regulator 2 (FXYD2)gammaa as a pancreatic beta cell-specific biomarker
Diabetologia
2010
53: 1372-1383
|
| 22896585 |
Estrada IA et al.:
STIM1 restores coronary endothelial function in type 1 diabetic mice
Circ. Res.
2012
111: 1166-1175
|
| 23723009 |
Radu BM et al.:
Advanced Type 1 Diabetes is Associated with ASIC Alterations in Mouse Lower Thoracic Dorsal Root Ganglia Neurons
Cell Biochem. Biophys.
2014
68: 9-23
|
| 23039284 |
Durand CA et al.:
Selective pharmacological inhibition of phosphoinositide 3-kinase p110delta opposes the progression of autoimmune diabetes in non-obese diabetic (NOD) mice
Autoimmunity
2013
46: 62-73
|
| 18201552 |
Yokoi N et al.:
Identification and functional analysis of CBLB mutations in type 1 diabetes
Biochem. Biophys. Res. Commun.
2008
368: 37-42
|
| 28101643 |
Assmann TS et al.:
Polymorphisms in genes encoding miR-155 and miR-146a are associated with protection to type 1 diabetes mellitus
Acta Diabetol
2017
54: 433-441
|
| 28396876 |
Liu XY et al.:
Reduced Histone H3 Lysine 9 Methylation Contributes to the Pathogenesis of Latent Autoimmune Diabetes in Adults via Regulation of SUV39H2 and KDM4C
J Diabetes Res
2017
2017
|
| 21980299 |
Bradfield JP et al. et al.:
A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci
PLoS Genet.
2011
7
|
| 30970177 |
Onuma H et al. et al.:
Variants in the BACH2 and CLEC16A gene might be associated with susceptibility to insulin-triggered type 1 diabetes
J Diabetes Investig
2019
10: 1447-1453
|
| 32476252 |
Coomans de Brachene A et al.:
Preclinical evaluation of tyrosine kinase 2 inhibitors for human beta-cell protection in type 1 diabetes
|
| 26661414 |
Sjakste T et al.:
Genetic variations in the PSMA3, PSMA6 and PSMC6 genes are associated with type 1 diabetes in Latvians and with expression level of number of UPS-related and T1DM-susceptible genes in HapMap individuals
Mol. Genet. Genomics
2016
291: 891-903
|
| 17676041 |
Lowe CE et al. et al.:
Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
Nat. Genet.
2007
39: 1074-1082
|
| 26107514 |
Hoelen H et al. et al.:
Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97
PLoS One
2015
10
|
| 30766706 |
Kim C et al.:
Anti-Mullerian hormone and its relationships with subclinical cardiovascular disease and renal disease in a longitudinal cohort study of women with type 1 diabetes
Womens Midlife Health
2017
3: 5
|
| 27475411 |
Kim C et al.:
Antimullerian hormone among women with and without type 1 diabetes: the Epidemiology of Diabetes Interventions and Complications Study and the Michigan Bone Health and Metabolism Study
Fertil Steril
2016
106: 1446-1452
|
| 22279428 |
author information missing
Discovery of early-stage biomarkers for diabetic kidney disease using ms-based metabolomics (FinnDiane study)
Metabolomics
2012
8: 109-119
|
| 22837797 |
et al.:
Serum insulin-like growth factor binding protein 6 (IGFBP6) is increased in patients with type 1 diabetes and its complications
Int J Clin Exp Med
2012
5: 229-237
|
| 31705008 |
Tofte N et al.:
Lipidomic analysis reveals sphingomyelin and phosphatidylcholine species associated with renal impairment and all-cause mortality in type 1 diabetes
Sci Rep
2019
9: 16398
|
| 31079532 |
Tang J et al.:
Urinary Renin in Patients and Mice With Diabetic Kidney Disease
Hypertension
2019
74: 83-94
|
| 26912320 |
author information missing
article information missing
|
| 34225445 |
author information missing
article information missing
|
| 18840781 |
author information missing
article information missing
|
| 25038750 |
author information missing
article information missing
|
| 35502705 |
author information missing
article information missing
|
| 15470032 |
author information missing
article information missing
|
| 24342660 |
author information missing
article information missing
|
| 24204704 |
author information missing
article information missing
|
| 34020532 |
author information missing
article information missing
|
| 21308987 |
Sebastio G et al.:
Lysinuric protein intolerance: reviewing concepts on a multisystem disease
Am J Med Genet C Semin Med Genet
2011
157C: 54-62
|
| 11544277 |
Kamada Y et al. et al.:
Vascular endothelial dysfunction resulting from L-arginine deficiency in a patient with lysinuric protein intolerance
J. Clin. Invest.
2001
108: 717-724
|
| 10080182 |
Torrents D et al. et al.:
Identification of SLC7A7, encoding y+LAT-1, as the lysinuric protein intolerance gene
Nat. Genet.
1999
21: 293-296
|
| 31427715 |
Kang E et al.:
Lysinuric protein intolerance with homozygous SLC7A7 mutation caused by maternal uniparental isodisomy of chromosome 14
J. Hum. Genet.
2019
64: 1137-1140
|
| 28028301 |
Habib A et al.:
Biochemical and molecular characteristics of Malaysian patients with lysinuric protein intolerance
Malays J Pathol
2016
38: 305-310
|
| 29616026 |
Rotoli BM et al.:
Downregulation of SLC7A7 Triggers an Inflammatory Phenotype in Human Macrophages and Airway Epithelial Cells
Front Immunol
2018
9: 508
|
| 17764084 |
Sperandeo MP et al.:
Lysinuric protein intolerance: update and extended mutation analysis of the SLC7A7 gene
Hum. Mutat.
2008
29: 14-21
|
| 19215041 |
Garavelli L et al.:
Mowat-Wilson syndrome: facial phenotype changing with age: study of 19 Italian patients and review of the literature
Am. J. Med. Genet. A
2009
149A: 417-426
|
| 20800523 |
Martinez AI et al.:
Genetic, structural and biochemical basis of carbamoyl phosphate synthetase 1 deficiency
Mol. Genet. Metab.
2010
101: 311-323
|
| 21941437 |
Haberle J et al.:
Role of carglumic acid in the treatment of acute hyperammonemia due to N-acetylglutamate synthase deficiency
Ther Clin Risk Manag
2011
7: 327-332
|
| 12942317 |
Belanger-Quintana A et al.:
Hyperammonaemia as a cause of psychosis in an adolescent
Eur. J. Pediatr.
2003
162: 773-775
|
| 18978333 |
Debray FG et al.:
Phenotypic variability among patients with hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome homozygous for the delF188 mutation in SLC25A15
J. Med. Genet.
2008
45: 759-764
|
| 12807890 |
Fiermonte G et al.:
The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms
J. Biol. Chem.
2003
278
|
| 17209980 |
Hung PC et al.:
A previously undescribed leukodystrophy in Leigh syndrome associated with T9176C mutation of the mitochondrial ATPase 6 gene
Dev Med Child Neurol
2007
49: 65-67
|
| 17186472 |
Lopez LC et al.:
Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations
Am. J. Hum. Genet.
2006
79: 1125-1129
|
| 25240982 |
Mori M et al.:
m.8993T>G-Associated Leigh Syndrome with Hypocitrullinemia on Newborn Screening
JIMD Rep
2014
17: 47-51
|
| 19669818 |
Shuk-kuen Chau C et al.:
Maternally inherited Leigh syndrome: an unusual cause of infantile apnea
Sleep Breath
2010
14: 161-165
|
| 19433277 |
Mkaouar-Rebai E et al.:
Maternally inherited Leigh syndrome: T8993G mutation in a Tunisian family
Pediatr. Neurol.
2009
40: 437-442
|
| 23206802 |
Honzik T et al.:
Different laboratory and muscle biopsy findings in a family with an m.8851T>C mutation in the mitochondrial MTATP6 gene
Mol. Genet. Metab.
2013
108: 102-105
|
| 16217706 |
Moslemi AR et al.:
Two new mutations in the MTATP6 gene associated with Leigh syndrome
Neuropediatrics
2005
36: 314-318
|
| 20301352 |
Pagon RA et al.:
Mitochondrial DNA-Associated Leigh Syndrome and NARP }, authors { names ml { Thorburn DR, Rahman S } }, from book { title { name GeneReviews(R) }, authors { names std { { name ml Pagon RA, role editor }, { name ml Adam MP, role editor }, { name ml Ardinger HH, role editor }, { name ml Wallace SE, role editor }, { name ml Amemiya A, role editor }, { name ml Bean LJH, role editor }, { name ml Bird TD, role editor }, { name ml Dolan CR, role editor }, { name ml Fong CT, role editor }, { name ml Smith RJH, role editor }, { name ml Stephens K, role editor } } }, imp { date std { year 1993 }, language eng, pubstatus ppublish, history { { pubstatus pubmed, date std { year 2010, month 3, day 20 } }, { pubstatus medline, date std { year 2010, month 3, day 20 } }, { pubstatus other, date std { year 2010, month 3, day 20 } } } } }, ids { pubmed 20301352, other { db bookaccession, tag str NBK1173 } } }, abstract Mitochondrial (mt) DNA-associated Leigh syndrome and NARP (neurogenic muscle weakness, ataxia, and retinitis pigmentosa) are part of a continuum of progressive neurodegenerative disorders caused by abnormalities of mitochondrial energy generation. Leigh syndrome (or subacute necrotizing encephalomyelopathy) is characterized by onset of symptoms typically between age three and 12 months, often following a viral infection. Decompensation (often with elevated lactate levels in blood and/or CSF) during an intercurrent illness is typically associated with psychomotor retardation or regression. Neurologic features include hypotonia, spasticity, movement disorders (including chorea), cerebellar ataxia, and peripheral neuropathy. Extraneurologic manifestations may include hypertrophic cardiomyopathy. About 50% of affected individuals die by age three years, most often as a result of respiratory or cardiac failure. NARP is characterized by proximal neurogenic muscle weakness with sensory neuropathy, ataxia, and pigmentary retinopathy. Onset of symptoms, particularly ataxia and learning difficulties, is often in early childhood. Individuals with NARP can be relatively stable for many years, but may suffer episodic deterioration, often in association with viral illnesses. The diagnosis of NARP and mtDNA-associated Leigh syndrome is established using clinical criteria and molecular genetic testing. MT-ATP6, MT-TL1, MT-TK, MT-TW, MT-TV, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND5, MT-ND6, and MT-CO3 are the mitochondrial genes in which pathogenic variants are known to cause mtDNA-associated Leigh syndrome. MT-ATP6 is the only gene in which pathogenic variants are known to cause NARP. Approximately 10% of individuals with Leigh syndrome have either the m.8993T>G or m.8993T>C MT-ATP6 pathogenic variant; approximately 10%-20% have pathogenic variants in other mitochondrial genes. The proportion of individuals with NARP who have a detectable pathogenic variant at MT-ATP6 nucleotide 8993 is unknown but likely greater than 50%; a T-to-G transversion (m.8993T>G) is most common; a T-to-C transition (m.8993T>C) has also been described. Treatment of manifestations: Supportive treatment includes use of sodium bicarbonate or sodium citrate for acidosis and antiepileptic drugs for seizures. Dystonia is treated with benzhexol, baclofen, tetrabenezine, and gabapentin alone or in combination, or by injections of botulinum toxin. Anticongestive therapy may be required for cardiomyopathy. Regular nutritional assessment of daily caloric intake and adequacy of diet and psychological support for the affected individual and family are essential. Surveillance: Neurologic, ophthalmologic, and cardiologic evaluations at regular intervals to monitor progression and appearance of new symptoms. Agents/circumstances to avoid: Sodium valproate and barbiturates, anesthesia, and dichloroacetate (DCA). Mitochondrial DNA-associated Leigh syndrome and NARP are transmitted by maternal inheritance. The father of a proband is not at risk of having the mtDNA pathogenic variant. The mother of a proband usually has the mtDNA pathogenic variant and may or may not have symptoms. In most cases, the mother has a much lower mutant load than the proband and usually remains asymptomatic or develops only mild symptoms. Occasionally the mother has a substantial mutant load and develops severe symptoms in adulthood. Offspring of males with a mtDNA pathogenic variant are not at risk; all offspring of females with a mtDNA pathogenic variant are at risk of inheriting the pathogenic variant. The risk to offspring of a female proband of developing symptoms depends on the tissue distribution and mutant load of the mtDNA pathogenic variant. Prenatal diagnosis and preimplantation genetic diagnosis for couples at increased risk of having children with mitochondrial DNA-associated Leigh syndrome and NARP is possible by analysis of mtDNA extracted from non-cultured fetal cells or from single blastomeres, respectively; however, the use of molecular genetic test results to predict long-term outcome is difficult
|
| 24100632 |
Imagawa E et al.:
A hemizygous GYG2 mutation and Leigh syndrome: a possible link? }, authors { names std { { name ml Imagawa E, affil str Department of Human Genetics, Yokohama City University Graduate School of Medicine, Yokohama, 236-0004, Japan
Hum. Genet.
2014
133: 225-234
|
| 8240753 |
Jung KC et al.:
Leighs disease involving multiple organs
J. Korean Med. Sci.
1993
8: 214-220
|
| 17352390 |
Castagna AE et al.:
Late onset Leigh syndrome and ataxia due to a T to C mutation at bp 9,185 of mitochondrial DNA
Am. J. Med. Genet. A
2007
143A: 808-816
|
| 15801966 |
Goerttler PS et al.:
Gene expression profiling in polycythaemia vera: overexpression of transcription factor NF-E2.
Br. J. Haematol.
2005
129: 138-150
|
| 21517843 |
Terwel D et al.:
Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilsons disease
J. Neurochem.
2011
118: 105-112
|
| 9920665 |
Borjigin J et al.:
A novel pineal night-specific ATPase encoded by the Wilson disease gene
J. Neurosci.
1999
19: 1018-1026
|
| 20103563 |
Klaassen CD et al.:
Xenobiotic, bile acid, and cholesterol transporters: function and regulation
Pharmacol. Rev.
2010
62: 1-96
|
| 20454597 |
Gupta A et al.:
Human copper transporters: mechanism, role in human diseases and therapeutic potential
Future Med Chem
2009
1: 1125-1142
|
| 30709419 |
Mordaunt CE et al. et al.:
Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers
Epigenetics Chromatin
2019
12: 10
|
| 20946626 |
Devuyst O et al.:
Dents disease
Orphanet J Rare Dis
2010
5: 28
|
| 20430975 |
Novarino G et al.:
Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis
Science
2010
328: 1398-1401
|
| 15238429 |
Knudson M et al.:
Association of immune abnormalities with telomere shortening in autosomal-dominant dyskeratosis congenita
Blood
2005
105: 682-688
|
| 25011434 |
Lee JH et al.:
OTC gene in ornithine transcarbamylase deficiency: clinical course and mutational spectrum in seven Korean patients
Pediatr. Neurol.
2014
51: 354-359
|
| 18364389 |
Chevalier-Larsen ES et al.:
Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin
Hum. Mol. Genet.
2008
17: 1946-1955
|
| 25580532 |
Serpente M et al.:
Profiling of ubiquitination pathway genes in peripheral cells from patients with frontotemporal dementia due to C9ORF72 and GRN mutations
Int J Mol Sci
2015
16: 1385-1394
|
| 30507613 |
Haliyur R et al. et al.:
Human islets expressing HNF1A variant have defective beta cell transcriptional regulatory networks
J Clin Invest
2019
129: 246-251
|
| 33472798 |
Oliveira RV et al.:
Monogenic diabetes: a new pathogenic variant of HNF1A gene
|
| 33245425 |
Schnedl WJ et al.:
Diagnosis of hepatic nuclear factor 1A monogenic diabetes mellitus (HNF1A-MODY) impacts antihyperglycemic treatment
|
| 32711050 |
Sato Y et al.:
HNF1alpha controls glucagon secretion in pancreatic alpha-cells through modulation of SGLT1
Biochim Biophys Acta Mol Basis Dis
2020
1866
|
| 32325224 |
Yau D et al.:
Congenital hyperinsulinism due to mutations in HNF1A
Eur J Med Genet
2020
63
|
| 21383009 |
Lee YC et al.:
Insulin-like growth factor-binding protein-3 (IGFBP-3) blocks the effects of asthma by negatively regulating NF-kappaB signaling through IGFBP-3R-mediated activation of caspases
J. Biol. Chem.
2011
286
|
| 20182505 |
Breslow DK et al.:
Orm family proteins mediate sphingolipid homeostasis
Nature
2010
463: 1048-1053
|
| 25691431 |
Siow D et al.:
ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis
J. Lipid Res.
2015
56: 898-908
|
| 21966607 |
Shin SW et al.:
Asthma-predictive genetic markers in gene expression profiling of peripheral blood mononuclear cells
Allergy Asthma Immunol Res
2011
3: 265-272
|
| 23046476 |
DeWan AT et al.:
Whole-exome sequencing of a pedigree segregating asthma
BMC Med. Genet.
2012
13: 95
|
| 19715394 |
Baines KJ et al.:
The nutrigenomics of asthma: molecular mechanisms of airway neutrophilia following dietary antioxidant withdrawal
OMICS
2009
13: 355-365
|
| 32348692 |
Peters MC et al. et al.:
COVID-19-related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids
Am. J. Respir. Crit. Care Med.
2020
202: 83-90
|
| 31262043 |
Schmidt H et al.:
IL-13 Impairs Tight Junctions in Airway Epithelia
|
| 30224386 |
Chen S et al.:
USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein
J. Exp. Med.
2018
215: 2850-2867
|
| 17576778 |
Gorska MM et al.:
MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation
J. Exp. Med.
2007
204: 1637-1652
|
| 21907864 |
author information missing
article information missing
|
| 30552067 |
author information missing
article information missing
|
| 19023099 |
Luke MM et al.:
Gene variants associated with ischemic stroke: the cardiovascular health study
Stroke
2009
40: 363-368
|
| 25807139 |
Sharma R et al.:
Proteomic Signature of Endothelial Dysfunction Identified in the Serum of Acute Ischemic Stroke Patients by the iTRAQ-Based LC-MS Approach
J. Proteome Res.
2015
14: 2466-2479
|
| 22591946 |
Oh SH et al.:
Alteration of immunologic responses on peripheral blood in the acute phase of ischemic stroke: blood genomic profiling study
J. Neuroimmunol.
2012
249: 60-65
|
| 26159646 |
Hu Z et al.:
Variants in the Atherogenic ALOX5AP, THBD, and KNG1 Genes Potentiate the Risk of Ischemic Stroke via a Genetic Main Effect and Epistatic Interactions in a Chinese Population
J Stroke Cerebrovasc Dis
2015
24: 2060-2068
|
| 22701019 |
Sabater-Lleal M et al.:
A genome-wide association study identifies KNG1 as a genetic determinant of plasma factor XI Level and activated partial thromboplastin time
Arterioscler. Thromb. Vasc. Biol.
2012
32: 2008-2016
|
| 27772792 |
Huang S et al.:
The homocysteine associated variant rs548987 of SLC17A3 confers susceptibility to ischemic stroke in Chinese population
J. Neurol. Sci.
2016
370: 78-81
|
| 29416106 |
Zhou Z et al.:
Plasma homocysteine concentrations and risk of intracerebral hemorrhage: a systematic review and meta-analysis
Sci Rep
2018
8: 2568
|
| 24338010 |
Albright RA et al.:
Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke
J. Biol. Chem.
2014
289: 3294-3306
|
| 25961151 |
Auer PL et al. et al.:
Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project
JAMA Neurol
2015
72: 781-788
|
| 24397542 |
Wu G et al.:
Genetic polymorphism of ITGA2 C807T can increase the risk of ischemic stroke
Int. J. Neurosci.
2014
124: 841-851
|
| 12215446 |
Wang X et al.:
Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice
J. Biol. Chem.
2002
277
|
| 29440987 |
Koronowski KB et al.:
Metabolomics Based Identification of SIRT5 and Protein Kinase C Epsilon Regulated Pathways in Brain
Front Neurosci
2018
12: 32
|
| 31926564 |
Ye XC et al. et al.:
Dectin-1/Syk signaling triggers neuroinflammation after ischemic stroke in mice
J Neuroinflammation
2020
17: 17
|
| 29663377 |
Huang Y et al.:
UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells
J. Cell. Physiol.
2018
233: 7480-7496
|
| 28611085 |
Arunachalam P et al.:
CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing gammadelta T Cells in Stroke
Stroke
2017
48: 1957-1965
|
| 24198371 |
Deb I et al.:
Neuroprotective role of a brain-enriched tyrosine phosphatase, STEP, in focal cerebral ischemia
J. Neurosci.
2013
33
|
| 17721624 |
Munoz X et al.:
Association of specific haplotypes of GAS6 gene with stroke
Thromb. Haemost.
2007
98: 406-412
|
| 31168961 |
Zhang Q et al.:
Identification of key genes and upstream regulators in ischemic stroke
Brain Behav
2019
9
|
| 35067807 |
author information missing
article information missing
|
| 18396140 |
Birsoy K et al.:
Transcriptional regulation of adipogenesis by KLF4.
Cell Metab.
2008
7: 339-347
|
| 15016818 |
Yoshizaki T et al.:
Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes
J. Biol. Chem.
2004
279
|
| 18058852 |
Guerdjikova AI et al.:
High-dose escitalopram in the treatment of binge-eating disorder with obesity: a placebo-controlled monotherapy trial
Hum Psychopharmacol
2008
23: 1-11
|
| 23652383 |
Mutschler J et al.:
Functional polymorphism in the neuropeptide Y gene promoter (rs16147) is associated with serum leptin levels and waist-hip ratio in women
Ann. Nutr. Metab.
2013
62: 271-276
|
| 23949303 |
Kulkarni SR et al.:
Effect of Caloric Restriction and AMPK Activation on Hepatic Nuclear Receptor, Biotransformation Enzyme, and Transporter Expression in Lean and Obese Mice
Pharm. Res.
2013
30: 2232-2247
|
| 21726512 |
Henkel AS et al.:
Hepatic overexpression of abcb11 promotes hypercholesterolemia and obesity in mice
Gastroenterology
2011
141: 1404-1411
|
| 9480839 |
Barthel A et al.:
Protein kinase C modulates the insulin-stimulated increase in Akt1 and Akt3 activity in 3T3-L1 adipocytes
Biochem. Biophys. Res. Commun.
1998
243: 509-513
|
| 20020228 |
author information missing
Gene expression profiles of a mouse congenic strain carrying an obesity susceptibility QTL under obesigenic diets
Genes Nutr
2010
5: 237-250
|
| 19948881 |
Maekawa T et al.:
The role of ATF-2 family transcription factors in adipocyte differentiation: antiobesity effects of p38 inhibitors
Mol. Cell. Biol.
2010
30: 613-625
|
| 12663464 |
Brozinick JT Jr et al.:
Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance
Diabetes
2003
52: 935-941
|
| 24190680 |
Hart CN et al.:
Changes in childrens sleep duration on food intake, weight, and leptin
Pediatrics
2013
132
|
| 26347385 |
Favennec M et al.:
The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation
Obesity (Silver Spring)
2015
23: 2066-2074
|
| 25605802 |
Gustafson B et al.:
BMP4 and BMP Antagonists Regulate Human White and Beige Adipogenesis
Diabetes
2015
64: 1670-1681
|
| 22074948 |
Sanchez-Solana B et al.:
Mouse resistin modulates adipogenesis and glucose uptake in 3T3-L1 preadipocytes through the ROR1 receptor
Mol. Endocrinol.
2012
26: 110-127
|
| 19481557 |
Shen L et al.:
Up-regulation of apolipoprotein E by leptin in the hypothalamus of mice and rats
Physiol. Behav.
2009
98: 223-228
|
| 28100511 |
Jennings A et al.:
Higher dietary flavonoid intakes are associated with lower objectively measured body composition in women: evidence from discordant monozygotic twins
Am. J. Clin. Nutr.
2017
105: 626-634
|
| 29212275 |
Zhou J et al.:
Physical exercises and weight loss in obese patients help to improve uric acid
Oncotarget
2017
8
|
| 3018195 |
et al.:
Adenosine stimulates glycogenolysis in mouse cerebral cortex: a possible coupling mechanism between neuronal activity and energy metabolism
J. Neurosci.
1986
6: 2558-2562
|
| 21859364 |
Jadhav AA et al.:
Elevated adenosine deaminase activity in overweight and obese Indian subjects
Arch. Physiol. Biochem.
2012
118: 1-5
|
| 30206336 |
Seck EH et al. et al.:
Salt in stools is associated with obesity, gut halophilic microbiota and Akkermansia muciniphila depletion in humans
|
| 29273807 |
Turcot V et al. et al.:
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Nat. Genet.
2018
50: 26-41
|
| 30158592 |
Song NJ et al. et al.:
PI3Ka-Akt1-mediated Prdm4 induction in adipose tissue increases energy expenditure, inhibits weight gain, and improves insulin resistance in diet-induced obese mice
Cell Death Dis
2018
9: 876
|
| 27159578 |
Song NJ et al. et al.:
Prdm4 induction by the small molecule butein promotes white adipose tissue browning
Nat. Chem. Biol.
2016
12: 479-481
|
| 28489853 |
Serra-Juhe C et al.:
Novel genes involved in severe early-onset obesity revealed by rare copy number and sequence variants
PLoS Genet.
2017
13
|
| 16494846 |
Gupte A et al.:
Activation of the Cbl insulin signaling pathway in cardiac muscle; dysregulation in obesity and diabetes
Biochem. Biophys. Res. Commun.
2006
342: 751-757
|
| 23512805 |
Lackey DE et al. et al.:
Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity
Am. J. Physiol. Endocrinol. Metab.
2013
304
|
| 25141837 |
Seeger T et al.:
Long-term inhibition of miR-21 leads to reduction of obesity in db/db mice
Obesity (Silver Spring)
2014
22: 2352-2360
|
| 28178239 |
Arif A et al. et al.:
EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice
Nature
2017
542: 357-361
|
| 20173393 |
Tzanavari T et al.:
TNF-alpha and obesity
Curr. Dir. Autoimmun.
2010
11: 145-156
|
| 15671113 |
Meyre D et al.:
Is glutamate decarboxylase 2 (GAD2) a genetic link between low birth weight and subsequent development of obesity in children?
J. Clin. Endocrinol. Metab.
2005
90: 2384-2390
|
| 11908756 |
Irizarry K et al.:
Single nucleotide polymorphism identification in candidate gene systems of obesity
Pharmacogenomics J.
2001
1: 193-203
|
| 30471861 |
Kobayashi M et al. et al.:
Identification of WWP1 as an obesity-associated E3 ubiquitin ligase with a protective role against oxidative stress in adipocytes
Biochem. Biophys. Res. Commun.
2019
508: 117-122
|
| 23885017 |
Huang H et al.:
ROCK1 in AgRP neurons regulates energy expenditure and locomotor activity in male mice
Endocrinology
2013
154: 3660-3670
|
| 22941110 |
Huang H et al. et al.:
Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling
Nat. Neurosci.
2012
15: 1391-1398
|
| 30824200 |
DeChristopher B et al. et al.:
Discovery of a small molecule RXFP3/4 agonist that increases food intake in rats upon acute central administration
Bioorg. Med. Chem. Lett.
2019
29: 991-994
|
| 23015752 |
Suter MA et al.:
Maternal high-fat diet modulates the fetal thyroid axis and thyroid gene expression in a nonhuman primate model
Mol. Endocrinol.
2012
26: 2071-2080
|
| 10440591 |
Goodfriend TL et al.:
Visceral obesity and insulin resistance are associated with plasma aldosterone levels in women
Obes. Res.
1999
7: 355-362
|
| 15630041 |
Engeli S et al.:
Weight loss and the renin-angiotensin-aldosterone system
Hypertension
2005
45: 356-362
|
| 23217260 |
Derecka M et al. et al.:
Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity
Cell Metab.
2012
16: 814-824
|
| 27077115 |
Sekine S et al.:
The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress
EBioMedicine
2016
5: 82-92
|
| 30652413 |
Miranda-Lora AL et al.:
Genetic polymorphisms associated with pediatric-onset type 2 diabetes: A family-based transmission disequilibrium test and case-control study
Pediatr Diabetes
2019
20: 239-245
|
| 28024880 |
Jiang C et al.:
Embryonic ablation of neuronal VGF increases energy expenditure and reduces body weight
Neuropeptides
2017
64: 75-83
|
| 26562304 |
D'Amato F et al.:
VGF Peptide Profiles in Type 2 Diabetic Patients Plasma and in Obese Mice
PLoS ONE
2015
10
|
| 24634820 |
Csaki LS et al.:
Lipin-1 and lipin-3 together determine adiposity in vivo
Mol Metab
2013
3: 145-154
|
| 21304485 |
Jacobsson JA et al.:
Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children
Int J Obes (Lond)
2012
36: 119-129
|
| 20882379 |
Marrades MP et al.:
Orchestrated downregulation of genes involved in oxidative metabolic pathways in obese vs. lean high-fat young male consumers
J. Physiol. Biochem.
2011
67: 15-26
|
| 27421018 |
Kaewsutthi S et al.:
Exome sequencing in Thai patients with familial obesity
|
| 15472169 |
Gibson WT et al.:
Congenital leptin deficiency due to homozygosity for the Delta133G mutation: report of another case and evaluation of response to four years of leptin therapy
J. Clin. Endocrinol. Metab.
2004
89: 4821-4826
|
| 30217759 |
Fu L et al.:
Gene-gene interactions and associations of six hypertension related single nucleotide polymorphisms with obesity risk in a Chinese children population
Gene
2018
679: 320-327
|
| 31488013 |
Chen Y et al.:
The inhibition of Nrf2 accelerates renal lipid deposition through suppressing the ACSL1 expression in obesity-related nephropathy
Ren Fail
2019
41: 821-831
|
| 25370576 |
Yau SW et al.:
IGFBP-2 inhibits adipogenesis and lipogenesis in human visceral, but not subcutaneous, adipocytes
Int J Obes (Lond)
2015
39: 770-781
|
| 21952248 |
Samuvel DJ et al.:
TLR4 activation and IL-6-mediated cross talk between adipocytes and mononuclear cells synergistically stimulate MMP-1 expression
Endocrinology
2011
152: 4662-4671
|
| 30860877 |
Larsen IS et al.:
Human Paneth cell alpha-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice
Am J Physiol Endocrinol Metab
2019
317: E42-E52
|
| 31049427 |
author information missing
article information missing
|
| 16705061 |
author information missing
article information missing
|
| 30568717 |
author information missing
article information missing
|
| 28403191 |
author information missing
article information missing
|
| 35673462 |
author information missing
article information missing
|
| 23804579 |
author information missing
article information missing
|
| 35788583 |
author information missing
article information missing
|
| 27175209 |
author information missing
article information missing
|
| 25907313 |
author information missing
article information missing
|
| 28299975 |
author information missing
article information missing
|
| 33889288 |
author information missing
article information missing
|
| 31915678 |
author information missing
article information missing
|
| 33057941 |
author information missing
article information missing
|
| 23724137 |
author information missing
article information missing
|
| 28469071 |
author information missing
article information missing
|
| 33176135 |
author information missing
article information missing
|
| 27408778 |
author information missing
article information missing
|
| 30837651 |
author information missing
article information missing
|
| 39807633 |
author information missing
article information missing
|
| 34964047 |
author information missing
article information missing
|
| 26829592 |
author information missing
article information missing
|
| 35395842 |
author information missing
article information missing
|
| 29205155 |
author information missing
article information missing
|
| 23869016 |
author information missing
article information missing
|
| 36692018 |
author information missing
article information missing
|
| 28959025 |
author information missing
article information missing
|
| 24399466 |
Hrycay E et al.:
Hepatic bile acid metabolism and expression of cytochrome P450 and related enzymes are altered in Bsep (-/-) mice
Mol. Cell. Biochem.
2014
389: 119-132
|
| 9806540 |
Strautnieks SS et al. et al.:
A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis
Nat. Genet.
1998
20: 233-238
|
| 11085914 |
Bingham C et al.:
Mutations in the hepatocyte nuclear factor-1beta gene are associated with familial hypoplastic glomerulocystic kidney disease
Am J Hum Genet
2001
68: 219-224
|
| 10720943 |
Bingham C et al. et al.:
Abnormal nephron development associated with a frameshift mutation in the transcription factor hepatocyte nuclear factor-1 beta
Kidney Int
2000
57: 898-907
|
| 17440011 |
Carette C et al.:
Exonic duplication of the hepatocyte nuclear factor-1beta gene (transcription factor 2, hepatic) as a cause of maturity onset diabetes of the young type 5
J Clin Endocrinol Metab
2007
92: 2844-2847
|
| 32864159 |
Mateus JC et al.:
Maturity-onset diabetes of the young type 5 a MULTISYSTEMIC disease: a CASE report of a novel mutation in the HNF1B gene and literature review
Clin Diabetes Endocrinol
2020
6: 16
|
| 32756155 |
Tao T et al.:
A novel HNF1B mutation p.R177Q in autosomal dominant tubulointerstitial kidney disease and maturity-onset diabetes of the young type 5: A pedigree-based case report
Medicine (Baltimore)
2020
99
|
| 31198537 |
Madariaga L et al.:
Variable phenotype in HNF1B mutations: extrarenal manifestations distinguish affected individuals from the population with congenital anomalies of the kidney and urinary tract
Clin Kidney J
2018
12: 373-379
|
| 31131422 |
Nagano C et al. et al.:
Clinical characteristics of HNF1B-related disorders in a Japanese population
Clin Exp Nephrol
2019
23: 1119-1129
|
| 31066763 |
Dotto RP et al. et al.:
Searching for mutations in the HNF1B gene in a Brazilian cohort with renal cysts and hyperglycemia
Arch Endocrinol Metab
2019
63: 250-257
|
| 30778115 |
Ricci P et al. et al.:
Urinary proteome signature of Renal Cysts and Diabetes syndrome in children
Sci Rep
2019
9: 2225
|
| 29764441 |
Pace NP et al.:
Case Report: Identification of an HNF1B p.Arg527Gln mutation in a Maltese patient with atypical early onset diabetes and diabetic nephropathy
BMC Endocr Disord
2018
18: 28
|
| 15142986 |
Wang L et al.:
Selective deletion of the Hnf1beta (MODY5) gene in beta-cells leads to altered gene expression and defective insulin release
Endocrinology
2004
145: 3941-3949
|
| 25715395 |
De Vas MG et al.:
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
Development
2015
142: 871-882
|
| 22706971 |
Roelandt P et al. et al.:
HNF1B deficiency causes ciliary defects in human cholangiocytes
Hepatology
2012
56: 1178-1181
|
| 21768539 |
Suetomi T et al.:
Mutation-linked defective interdomain interactions within ryanodine receptor cause aberrant Ca(2)(+)release leading to catecholaminergic polymorphic ventricular tachycardia
Circulation
2011
124: 682-694
|
| 12417987 |
Chagnon P et al.:
A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis
Am. J. Hum. Genet.
2002
71: 1443-1449
|
| 15181075 |
Yorifuji T et al.:
Neonatal diabetes mellitus and neonatal polycystic, dysplastic kidneys: Phenotypically discordant recurrence of a mutation in the hepatocyte nuclear factor-1beta gene due to germline mosaicism
J Clin Endocrinol Metab
2004
89: 2905-2908
|
| 14578306 |
Njolstad PR et al.:
Permanent neonatal diabetes caused by glucokinase deficiency: inborn error of the glucose-insulin signaling pathway
Diabetes
2003
52: 2854-2860
|
| 15122254 |
Evgrafov OV et al.:
Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy
Nat. Genet.
2004
36: 602-606
|
| 30100715 |
Heinbockel L et al.:
Identification of novel target genes in human lung tissue involved in chronic obstructive pulmonary disease
Int J Chron Obstruct Pulmon Dis
2018
13: 2255-2259
|
| 24223650 |
He Z et al.:
Merosin-deficient congenital muscular dystrophy type 1A: A case report
Exp Ther Med
2013
6: 1233-1236
|
| 22956851 |
Zhang J et al.:
Brefeldin A-inhibited guanine exchange factor 2 regulates filamin A phosphorylation and neuronal migration
J. Neurosci.
2012
32
|
| 12946103 |
Abbas S et al.:
Tumor necrosis factor-alpha inhibits pre-osteoblast differentiation through its type-1 receptor.
Cytokine
2003
22: 33-41
|
| 11163184 |
Yoshida Y et al.:
Negative regulation of BMP/Smad signaling by Tob in osteoblasts
Cell
2000
103: 1085-1097
|
| 20954177 |
Suwanwela J et al.:
Systems genetics analysis of mouse chondrocyte differentiation
J. Bone Miner. Res.
2011
26: 747-760
|
| 22196185 |
author information missing
article information missing
|
| 17277775 |
Cabral WA et al. et al.:
Prolyl 3-hydroxylase 1 deficiency causes a recessive metabolic bone disorder resembling lethal/severe osteogenesis imperfecta
Nat. Genet.
2007
39: 359-365
|
| 18386809 |
Kulkarni S et al.:
Disruption of chromodomain helicase DNA binding protein 2 (CHD2) causes scoliosis
Am. J. Med. Genet. A
2008
146
|
| 21159828 |
Nakki A et al.:
Candidate gene association study of magnetic resonance imaging-based hip osteoarthritis (OA): evidence for COL9A2 gene as a common predisposing factor for hip OA and lumbar disc degeneration
J. Rheumatol.
2011
38: 747-752
|
| 27329220 |
Mirzamohammadi F et al.:
Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-beta signalling
Nat Commun
2016
7: 12047
|
| 24643965 |
Alam I et al. et al.:
High-resolution genome screen for bone mineral density in heterogeneous stock rat
J. Bone Miner. Res.
2014
29: 1619-1626
|
| 28936620 |
author information missing
article information missing
|
| 31429852 |
Trancozo M et al. et al.:
Osteogenesis imperfecta in Brazilian patients
Genet. Mol. Biol.
2019
42: 344-350
|
| 19419969 |
Ishikawa Y et al.:
Biochemical characterization of the prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B complex
J. Biol. Chem.
2009
284
|
| 31822768 |
Ishikawa M et al.:
Pannexin 3 ER Ca(2+) channel gating is regulated by phosphorylation at the Serine 68 residue in osteoblast differentiation
Sci Rep
2019
9: 18759
|
| 22560091 |
Rieder MJ et al. et al.:
A human homeotic transformation resulting from mutations in PLCB4 and GNAI3 causes auriculocondylar syndrome
Am. J. Hum. Genet.
2012
90: 907-914
|
| 26146596 |
Heuze Y et al.:
Closing the Gap: Genetic and Genomic Continuum from Syndromic to Nonsyndromic Craniosynostoses
Curr Genet Med Rep
2014
2: 135-145
|
| 3372533 |
Willing MC et al.:
Heterozygosity for a large deletion in the alpha 2(I) collagen gene has a dramatic effect on type I collagen secretion and produces perinatal lethal osteogenesis imperfecta
J. Biol. Chem.
1988
263: 8398-8404
|
| 21912751 |
Ben Amor IM et al.:
Genotype-phenotype correlations in autosomal dominant osteogenesis imperfecta
J Osteoporos
2011
2011
|
| 8786065 |
Lund AM et al.:
Deletion of a Gly-Pro-Pro repeat in the pro alpha2(I) chain of procollagen I in a family with dominant osteogenesis imperfecta type IV
Hum. Genet.
1996
97: 287-290
|
| 12960086 |
Sciaudone M et al.:
Notch 1 impairs osteoblastic cell differentiation
Endocrinology
2003
144: 5631-5639
|
| 21148317 |
Thaler R et al.:
Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1, and epigenetic DNA methylation
J. Biol. Chem.
2011
286: 5578-5588
|
| 15105378 |
Sun LQ et al.:
Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG
Genes Dev.
2004
18: 1035-1046
|
| 26090674 |
Chen J et al.:
mTORC1 Signaling Promotes Osteoblast Differentiation from Preosteoblasts
PLoS ONE
2015
10
|
| 22993228 |
Williams FM et al. et al.:
Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects
Ann. Rheum. Dis.
2013
72: 1141-1148
|
| 23963683 |
Chen X et al.:
Protein kinase inhibitor gamma reciprocally regulates osteoblast and adipocyte differentiation by downregulating leukemia inhibitory factor
Stem Cells
2013
31: 2789-2799
|
| 25642776 |
author information missing
Functional variants of POC5 identified in patients with idiopathic scoliosis
J. Clin. Invest.
2015
125: 1124-1128
|
| 30845169 |
Hassan A et al.:
Adolescent idiopathic scoliosis associated POC5 mutation impairs cell cycle, cilia length and centrosome protein interactions
PLoS ONE
2019
14
|
| 23665482 |
Grosch M et al. et al.:
Identification of a Ninein (NIN) mutation in a family with spondyloepimetaphyseal dysplasia with joint laxity (leptodactylic type)-like phenotype
Matrix Biol.
2013
32: 387-392
|
| 30917318 |
Ren X et al. et al.:
Maintenance of Nucleolar Homeostasis by CBX4 Alleviates Senescence and Osteoarthritis
Cell Rep
2019
26: 3643-3656.e7
|
| 26890063 |
Doucet M et al.:
CCL20/CCR6 Signaling Regulates Bone Mass Accrual in Mice
J. Bone Miner. Res.
2016
31: 1381-1390
|
| 30739146 |
Zhou Q et al.:
Differentially expressed proteins identified by TMT proteomics analysis in bone marrow microenvironment of osteoporotic patients
Osteoporos Int
2019
30: 1089-1098
|
| 32017075 |
Zhang Y et al.:
PSMC6 promotes osteoblast apoptosis through inhibiting PI3K/AKT signaling pathway activation in ovariectomy-induced osteoporosis mouse model
J. Cell. Physiol.
2020
235: 5511-5524
|
| 11084030 |
Katagiri M et al.:
Mechanism of stimulation of osteoclastic bone resorption through Gas6/Tyro 3, a receptor tyrosine kinase signaling, in mouse osteoclasts
J. Biol. Chem.
2001
276: 7376-7382
|
| 31541023 |
Xu C et al.:
Identification of a Novel Role for Foxo3 Isoform2 in Osteoclastic Inhibition
J. Immunol.
2019
203: 2141-2149
|
| 18394579 |
Alasti F et al.:
A mutation in HOXA2 is responsible for autosomal-recessive microtia in an Iranian family
Am J Hum Genet
2008
82: 982-991
|
| 31900200 |
Huang Y et al.:
Long non-coding RNA FER1L4 promotes osteogenic differentiation of human periodontal ligament stromal cells via miR-874-3p and vascular endothelial growth factor A
Stem Cell Res Ther
2020
11: 5
|
| 25100727 |
Zhao Y et al.:
C-terminal domain (CTD) small phosphatase-like 2 modulates the canonical bone morphogenetic protein (BMP) signaling and mesenchymal differentiation via Smad dephosphorylation
J. Biol. Chem.
2014
289
|
| 30450135 |
Akiyama M et al.:
Characterization of the F-box Proteins FBXW2 and FBXL14 in the Initiation of Bone Regeneration in Transplants given to Nude Mice
Open Biomed Eng J
2018
12: 75-89
|
| 29674611 |
Tang Q et al.:
Inhibition of Dll4/Notch1 pathway promotes angiogenesis of Masquelets induced membrane in rats
Exp Mol Med
2018
50: 41
|
| 28098876 |
Zhang Z et al.:
BDNF regulates the expression and secretion of VEGF from osteoblasts via the TrkB/ERK1/2 signaling pathway during fracture healing
Mol Med Rep
2017
15: 1362-1367
|
| 20940257 |
Takigawa Y et al.:
The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9
J Cell Sci
2010
123: 3780-3788
|
| 11308397 |
Paassilta P et al. et al.:
Identification of a novel common genetic risk factor for lumbar disk disease
JAMA
2001
285: 1843-1849
|
| 26211931 |
Rashidghamat E et al.:
Mutations in EXPH5 underlie a rare subtype of autosomal recessive epidermolysis bullosa simplex
Br. J. Dermatol.
2016
174: 452-453
|
| 23176819 |
McGrath JA et al. et al.:
Germline Mutation in EXPH5 Implicates the Rab27B Effector Protein Slac2-b in Inherited Skin Fragility
Am. J. Hum. Genet.
2012
91: 1115-1121
|
| 30016581 |
Vahidnezhad H et al. et al.:
Next generation sequencing identifies double homozygous mutations in two distinct genes (EXPH5 and COL17A1) in a patient with concomitant simplex and junctional epidermolysis bullosa
Hum. Mutat.
2018
39: 1349-1354
|
| 12754508 |
Levy-Nissenbaum E et al. et al.:
Hypotrichosis simplex of the scalp is associated with nonsense mutations in CDSN encoding corneodesmosin
Nat. Genet.
2003
34: 151-153
|
| 21191406 |
author information missing
Inflammatory peeling skin syndrome caused by a mutation in CDSN encoding corneodesmosin
J. Invest. Dermatol.
2011
131: 779-781
|
| 20691404 |
Oji V et al. et al.:
Loss of corneodesmosin leads to severe skin barrier defect, pruritus, and atopy: unraveling the peeling skin disease
Am. J. Hum. Genet.
2010
87: 274-281
|
| 27384765 |
Turcan I et al.:
Association of Epidermolysis Bullosa Simplex With Mottled Pigmentation and EXPH5 Mutations
JAMA Dermatol
2016
152: 1137-1141
|
| 8673107 |
Maestrini E et al.:
A molecular defect in loricrin, the major component of the cornified cell envelope, underlies Vohwinkels syndrome
Nat. Genet.
1996
13: 70-77
|
| 26142438 |
Klar J et al.:
Whole exome sequencing identifies LRP1 as a pathogenic gene in autosomal recessive keratosis pilaris atrophicans
J. Med. Genet.
2015
52: 599-606
|
| 23176819 |
McGrath JA et al. et al.:
Germline Mutation in EXPH5 Implicates the Rab27B Effector Protein Slac2-b in Inherited Skin Fragility
Am J Hum Genet
2012
91: 1115-1121
|
| 32890627 |
Bare Y et al.:
Slac2-b Coordinates Extracellular Vesicle Secretion to Regulate Keratinocyte Adhesion and Migration
J Invest Dermatol
2021
141: 523-532.e2
|
| 17145082 |
Hore I et al.:
The management of general and disease specific ENT problems in children with Epidermolysis Bullosa--a retrospective case note review
Int J Pediatr Otorhinolaryngol
2007
71: 385-391
|
| 31082377 |
Monteleon CL et al.:
Exophilin-5 Supports Lysosome-Mediated Trafficking Required for Epidermal Differentiation
J Invest Dermatol
2019
139: 2219-2222.e6
|
| 35280393 |
author information missing
article information missing
|
| 9169052 |
Hedgepeth CM et al.:
Activation of the Wnt signaling pathway: a molecular mechanism for lithium action
Dev. Biol.
1997
1: 82-91
|
| 26672496 |
Caterino M et al.:
The proteome of methylmalonic acidemia (MMA): the elucidation of altered pathways in patient livers
Mol Biosyst
2016
12: 566-574
|
| 28397811 |
Francois CM et al.:
A novel action of follicle-stimulating hormone in the ovary promotes estradiol production without inducing excessive follicular growth before puberty
Sci Rep
2017
7: 46222
|
| 20415579 |
Phang JM et al.:
Proline metabolism and microenvironmental stress
Annu. Rev. Nutr.
2010
30: 441-463
|
| 23238908 |
Anggono V et al.:
Glutamate Receptors in Alzheimers Disease: Mechanisms and Therapies
Neural Plast.
2016
2016
|
| 23048031 |
Chittka A et al.:
Transcription factor positive regulatory domain 4 (PRDM4) recruits protein arginine methyltransferase 5 (PRMT5) to mediate histone arginine methylation and control neural stem cell proliferation and differentiation
J. Biol. Chem.
2012
287
|
| 30048854 |
Zhang BH et al.:
VAX1 gene associated non-syndromic cleft lip with or without palate in Western Han Chinese
Arch. Oral Biol.
2018
95: 40-43
|
| 29445069 |
Guo S et al.:
Expression and distribution of the zinc finger protein, SNAI3, in mouse ovaries and pre-implantation embryos
J. Reprod. Dev.
2018
64: 179-186
|
| 9223334 |
Andres C et al.:
Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration
Proc. Natl. Acad. Sci. U.S.A.
1997
94: 8173-8178
|
| 29082339 |
Gomes C et al.:
DnaJC18, a Novel Type III DnaJ Family Protein, is Expressed Specifically in Rat Male Germ Cells
Dev Reprod
2017
21: 237-247
|
| 18301782 |
Mahajan MA et al.:
Nuclear receptor coactivator/coregulator NCoA6(NRC) is a pleiotropic coregulator involved in transcription, cell survival, growth and development
Nucl Recept Signal
2008
6: e002
|
| 26399832 |
Werner A et al.:
Cell-fate determination by ubiquitin-dependent regulation of translation
Nature
2015
525: 523-527
|
| 19765683 |
Pasutto F et al. et al.:
Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma
Am. J. Hum. Genet.
2009
85: 447-456
|
| 30993352 |
Wu J et al.:
Characterization of PPIB interaction in the P3H1 ternary complex and implications for its pathological mutations
Cell. Mol. Life Sci.
2019
76: 3899-3914
|
| 16810678 |
Marfella CG et al.:
Mutation of the SNF2 family member Chd2 affects mouse development and survival
J. Cell. Physiol.
2006
209: 162-171
|
| 31044088 |
Chan AJS et al. et al.:
Expanding the neurodevelopmental phenotypes of individuals with de novo KMT2A variants
NPJ Genom Med
2019
4: 9
|
| 28594414 |
Altmuller F et al. et al.:
Genotype and phenotype spectrum of NRAS germline variants
Eur J Hum Genet
2017
25: 823-831
|
| 28155855 |
Sagai T et al.:
Evolution of Shh endoderm enhancers during morphological transition from ventral lungs to dorsal gas bladder
Nat Commun
2017
8: 14300
|
| 29625437 |
Cao M et al.:
Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure
Invest. Ophthalmol. Vis. Sci.
2018
59: 1167-1177
|
| 29791854 |
Souquet B et al.:
Nup133 Is Required for Proper Nuclear Pore Basket Assembly and Dynamics in Embryonic Stem Cells
Cell Rep
2018
23: 2443-2454
|
| 24414074 |
Rodriguez-Menocal L et al.:
Macrophage-derived IL-18 and increased fibrinogen deposition are age-related inflammatory signatures of vascular remodeling
Am. J. Physiol. Heart Circ. Physiol.
2014
306: H641-H653
|
| 20569193 |
Pennings JL et al.:
Identification by gene coregulation mapping of novel genes involved in embryonic stem cell differentiation
Stem Cells Dev.
2011
20: 115-126
|
| 26416033 |
Kantaputra PN et al.:
GREMLIN 2 Mutations and Dental Anomalies
J. Dent. Res.
2015
94: 1646-1652
|
| 17222801 |
Im J et al.:
Wnt/beta-catenin signaling regulates expression of PRDC, an antagonist of the BMP-4 signaling pathway
Biochem. Biophys. Res. Commun.
2007
354: 296-301
|
| 30571656 |
Cui W et al.:
MED20 is essential for early embryogenesis and regulates NANOG expression
Reproduction
2019
157: 215-222
|
| 26100099 |
author information missing
ASXL2--director of skeletal and metabolic homeostasis
Nat Rev Endocrinol
2015
11: 445
|
| 30093396 |
Madan V et al. et al.:
ASXL2 regulates hematopoiesis in mice and its deficiency promotes myeloid expansion
Haematologica
2018
103: 1980-1990
|
| 17267443 |
Garcia-Rudaz C et al.:
Fxna, a novel gene differentially expressed in the rat ovary at the time of folliculogenesis, is required for normal ovarian histogenesis
Development
2007
134: 945-957
|
| 28874804 |
Peck SH et al.:
Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus
Sci Rep
2017
7: 10504
|
| 2777808 |
Weil D et al.:
Temperature-dependent expression of a collagen splicing defect in the fibroblasts of a patient with Ehlers-Danlos syndrome type VII
J. Biol. Chem.
1989
264
|
| 17955022 |
Lund AM et al.:
Deletion of a Gly-Pro-Pro repeat in the pro alpha2(I) chain of procollagen I in a family with dominant osteogenesis imperfecta type IV
Hum. Genet.
1996
97: 287-290
|
| 10581026 |
McGuirt WT et al. et al.:
Mutations in COL11A2 cause non-syndromic hearing loss (DFNA13)
Nat. Genet.
1999
23: 413-419
|
| 16033917 |
author information missing
Mutation of COL11A2 causes autosomal recessive non-syndromic hearing loss at the DFNB53 locus
J. Med. Genet.
2005
42: e61
|
| 22246659 |
Tompson SW et al.:
Dominant and recessive forms of fibrochondrogenesis resulting from mutations at a second locus, COL11A2
Am. J. Med. Genet. A
2012
158A: 309-314
|
| 7833911 |
Brunner HG et al.:
A Stickler syndrome gene is linked to chromosome 6 near the COL11A2 gene
Hum. Mol. Genet.
1994
3: 1561-1564
|
| 7859284 |
Vikkula M et al.:
Autosomal dominant and recessive osteochondrodysplasias associated with the COL11A2 locus
Cell
1995
80: 431-437
|
| 21246654 |
Dawe CE et al.:
Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development
Dev. Dyn.
2011
240: 372-383
|
| 9395522 |
Simon M et al.:
Characterization and purification of human corneodesmosin, an epidermal basic glycoprotein associated with corneocyte-specific modified desmosomes
J. Biol. Chem.
1997
272
|
| 22753498 |
Bustos MA et al.:
Rab27 and Rab3 sequentially regulate human sperm dense-core granule exocytosis
Proc. Natl. Acad. Sci. U.S.A.
2012
109
|
| 24482543 |
Santos-Cortez RL et al. et al.:
Adenylate cyclase 1 (ADCY1) mutations cause recessive hearing impairment in humans and defects in hair cell function and hearing in zebrafish
Hum. Mol. Genet.
2014
23: 3289-3298
|
| 26315608 |
Malishkevich A et al.:
ADNP/ADNP2 expression in oligodendrocytes: implication for myelin-related neurodevelopment
J. Mol. Neurosci.
2015
57: 304-313
|
| 23799577 |
Shang X et al.:
Changes in expression and distribution of attractin in the testes of rats at different developmental stages
Int. J. Mol. Med.
2013
32: 599-606
|
| 21490954 |
Farber CR et al. et al.:
Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis
PLoS Genet.
2011
7
|
| 26544806 |
Raza MH et al. et al.:
Association between Rare Variants in AP4E1, a Component of Intracellular Trafficking, and Persistent Stuttering
Am. J. Hum. Genet.
2015
97: 715-725
|
| 25037221 |
Kirschner KM et al.:
Amine oxidase copper-containing 1 (AOC1) is a downstream target gene of the Wilms tumor protein, WT1, during kidney development
J. Biol. Chem.
2014
289
|
| 1728594 |
Colbert MC et al.:
The proximal promoter of the aldolase A gene remains active during myogenesis in vitro and muscle development in vivo
Dev. Biol.
1992
149: 66-79
|
| 11357197 |
Raabe EH et al.:
An SNF2 factor involved in mammalian development and cellular proliferation
Dev. Dyn.
2001
221: 92-105
|
| 25494100 |
Rao Y et al.:
A Mec17-Myosin II Effector Axis Coordinates Microtubule Acetylation and Actin Dynamics to Control Primary Cilium Biogenesis
PLoS ONE
2014
9
|
| 25888806 |
Gladwyn-Ng IE et al.:
Bacurd2 is a novel interacting partner to Rnd2 which controls radial migration within the developing mammalian cerebral cortex
Neural Dev
2015
10: 9
|
| 31549732 |
Li P et al.:
Neuronal NLRC5 regulates MHC class I expression in Neuro-2a cells and also during hippocampal development
J. Neurochem.
2020
152: 182-194
|
| 24647604 |
Vieira NM et al. et al.:
A defect in the RNA-processing protein HNRPDL causes limb-girdle muscular dystrophy 1G (LGMD1G)
Hum. Mol. Genet.
2014
23: 4103-4110
|
| 28827407 |
Oka M et al. et al.:
Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos
J. Cell. Sci.
2017
130: 3568-3577
|
| 22292003 |
Huang YY et al.:
Requirement of mouse BCCIP for neural development and progenitor proliferation
PLoS ONE
2012
7
|
| 19008920 |
McPherson JP et al. et al.:
Essential role for Bclaf1 in lung development and immune system function
Cell Death Differ.
2009
16: 331-339
|
| 27534274 |
Wei Q et al.:
The hydrolethalus syndrome protein HYLS-1 regulates formation of the ciliary gate
Nat Commun
2016
7: 12437
|
| 14684875 |
Ueki T et al.:
A novel secretory factor, Neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus
J. Neurosci.
2003
23
|
| 20439720 |
Uchiyama Y et al. et al.:
Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 9240-9245
|
| 29621187 |
Karuna EP et al.:
Identification of a WNT5A-Responsive Degradation Domain in the Kinesin Superfamily Protein KIF26B
|
| 31197172 |
Shi L et al.:
Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion
Nat Commun
2019
10: 2588
|
| 20880987 |
Sevilla LM et al.:
Glucocorticoid receptor regulates overlapping and differential gene subsets in developing and adult skin
Mol. Endocrinol.
2010
24: 2166-2178
|
| 26094785 |
author information missing
Corrigendum: Genetic Analysis of the Role of the Reprogramming Gene LIN-28 in Human Embryonic Stem Cells
Stem Cells
2015
33: 2360
|
| 23449627 |
Cousminer DL et al. et al.:
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity
Hum. Mol. Genet.
2013
22: 2735-2747
|
| 29500366 |
Langford MB et al.:
Deletion of the Syncytin A receptor Ly6e impairs syncytiotrophoblast fusion and placental morphogenesis causing embryonic lethality in mice
Sci Rep
2018
8: 3961
|
| 30545550 |
Uzun Cilingir I et al.:
Deletion of macro domain containing 2(MACRO D2) associated with transient hydrops fetalis
Taiwan J Obstet Gynecol
2018
57: 897-898
|
| 32189007 |
Tenenbaum M et al. et al.:
The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development
|
| 32679066 |
Yue L et al. et al.:
Mthfd2 Modulates Mitochondrial Function and DNA Repair to Maintain the Pluripotency of Mouse Stem Cells
|
| 23807208 |
Kypri E et al.:
The nucleotide-binding proteins Nubp1 and Nubp2 are negative regulators of ciliogenesis
Cell. Mol. Life Sci.
2014
71: 517-538
|
| 31448844 |
Morin G et al. et al.:
Tubular aggregate myopathy and Stormorken syndrome: Mutation spectrum and genotype/phenotype correlation
Hum. Mutat.
2020
41: 17-37
|
| 18179896 |
Hejtmancik JF et al.:
Mutations in KCNJ13 cause autosomal-dominant snowflake vitreoretinal degeneration
Am. J. Hum. Genet.
2008
82: 174-180
|
| 31390291 |
Postema MM et al.:
PACSIN2-dependent apical endocytosis regulates the morphology of epithelial microvilli
Mol. Biol. Cell
2019
30: 2515-2526
|
| 29255294 |
Banerji CRS et al.:
PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle
Nat Commun
2017
8: 2152
|
| 28779497 |
Proskorovski-Ohayon R et al.:
PAX7 mutation in a syndrome of failure to thrive, hypotonia, and global neurodevelopmental delay
Hum. Mutat.
2017
38: 1671-1683
|
| 28102564 |
Danno S et al.:
PKN2 is essential for mouse embryonic development and proliferation of mouse fibroblasts
Genes Cells
2017
22: 220-236
|
| 23563607 |
Berndt SI et al. et al.:
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Nat. Genet.
2013
45: 501-512
|
| 31488212 |
Deegan DF et al.:
The developmental origins of sex-biased expression in cardiac development
Biol Sex Differ
2019
10: 46
|
| 27508494 |
Hayden LP et al.:
Susceptibility to Childhood Pneumonia: A Genome-Wide Analysis
Am. J. Respir. Cell Mol. Biol.
2017
56: 20-28
|
| 31562340 |
Akiyama M et al. et al.:
Characterizing rare and low-frequency height-associated variants in the Japanese population
Nat Commun
2019
10: 4393
|
| 30055035 |
Guo K et al.:
Ablation of Ggnbp2 impairs meiotic DNA double-strand break repair during spermatogenesis in mice
J. Cell. Mol. Med.
2018
22: 4863-4874
|
| 26764350 |
Li S et al. et al.:
Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation
Biol. Reprod.
2016
94: 41
|
| 25310821 |
Kim JH et al. et al.:
A genome-wide association study identifies potential susceptibility loci for Hirschsprung disease
PLoS ONE
2014
9
|
| 23270508 |
Fernandez RM et al. et al.:
Four new loci associations discovered by pathway-based and network analyses of the genome-wide variability profile of Hirschsprungs disease
Orphanet J Rare Dis
2012
7: 103
|
| 28049421 |
Buckberry S et al.:
Placental transcriptome co-expression analysis reveals conserved regulatory programs across gestation
BMC Genomics
2017
18: 10
|
| 15366017 |
Landgren H et al.:
FoxJ3, a novel mammalian forkhead gene expressed in neuroectoderm, neural crest, and myotome
Dev. Dyn.
2004
231: 396-401
|
| 22802087 |
Stanescu DE et al.:
Novel presentations of congenital hyperinsulinism due to mutations in the MODY genes: HNF1A and HNF4A
J. Clin. Endocrinol. Metab.
2012
97
|
| 22223247 |
Donaldson IJ et al.:
Genome-wide occupancy links Hoxa2 to Wnt-beta-catenin signaling in mouse embryonic development
Nucleic Acids Res.
2012
40: 3990-4001
|
| 15668942 |
Selcen D et al.:
Mutations in ZASP define a novel form of muscular dystrophy in humans
Ann. Neurol.
2005
57: 269-276
|
| 22548356 |
Deshpande AM et al.:
Cdk2ap2 is a novel regulator for self-renewal of murine embryonic stem cells
Stem Cells Dev.
2012
21: 3010-3018
|
| 11856312 |
Whitehouse C et al.:
NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube
Eur. J. Biochem.
2002
269: 538-545
|
| 30683896 |
Insinna C et al.:
Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport
Nat Commun
2019
10: 428
|
| 26058934 |
Rafati R et al.:
Association of rs12255372 (TCF7L2) and D76N (PDX-1) Polymorphisms with Type 2 Diabetes in a Population Living in Northeast Iran
Arch Iran Med
2015
18: 376-378
|
| 24478790 |
Lee JH et al. et al.:
Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study
Front Genet
2014
4: 310
|
| 32103185 |
Coulter ME et al. et al.:
Regulation of human cerebral cortical development by EXOC7 and EXOC8, components of the exocyst complex, and roles in neural progenitor cell proliferation and survival
Genet. Med.
2020
22: 1040-1050
|
| 32425970 |
van der Spek A et al. et al.:
Exome Sequencing Analysis Identifies Rare Variants in ATM and RPL8 That Are Associated With Shorter Telomere Length
Front Genet
2020
11: 337
|
| 25017066 |
Oh H et al.:
Yorkie promotes transcription by recruiting a histone methyltransferase complex
Cell Rep
2014
8: 449-459
|
| 31301300 |
Tessier S et al.:
NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis
Dev. Biol.
2019
455: 369-381
|
| 12588852 |
Chen W et al.:
The zinc-finger protein CNBP is required for forebrain formation in the mouse
Development
2003
130: 1367-1379
|
| 21907140 |
Moroishi T et al.:
The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo
Cell Metab
2011
14: 339-351
|
| 22698282 |
Barak H et al.:
FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man
Dev Cell
2012
22: 1191-1207
|
| 7689951 |
Latimer AM et al.:
The effects of thyroxine on serum and tissue concentrations of insulin-like growth factors (IGF-I and -II) and IGF-binding proteins in the fetal pig
Endocrinology
1993
133: 1312-1319
|
| 19961928 |
Song R et al.:
Angiotensin II-induced activation of c-Ret signaling is critical in ureteric bud branching morphogenesis
Mech Dev
2010
127: 21-27
|
| 10767088 |
Dehghani H et al.:
Effects of disruption of the embryonic alkaline phosphatase gene on preimplantation development of the mouse
Dev Dyn
2000
217: 440-448
|
| 29237753 |
Schutgens F et al.:
Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney
Proc Natl Acad Sci U S A
2017
114
|
| 25672900 |
Murtaza M et al.:
La FAM fatale: USP9X in development and disease
Cell Mol Life Sci
2015
72: 2075-2089
|
| 24120664 |
Adachi K et al.:
Context-dependent wiring of Sox2 regulatory networks for self-renewal of embryonic and trophoblast stem cells
Mol Cell
2013
52: 380-392
|
| 26791201 |
Theendakara V et al.:
Direct Transcriptional Effects of Apolipoprotein E
J Neurosci
2016
36: 685-700
|
| 23892456 |
Gagliardi A et al. et al.:
A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal
EMBO J
2013
32: 2231-2247
|
| 11032833 |
van Adelsberg J et al.:
Activation of hepatocyte growth factor (HGF) by endogenous HGF activator is required for metanephric kidney morphogenesis in vitro
J Biol Chem
2001
276
|
| 26638075 |
Gupta GD et al. et al.:
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface
Cell
2015
163: 1484-1499
|
| 23371553 |
Huang X et al. et al.:
Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling
Science
2013
339: 1441-1445
|
| 16597514 |
Deng M et al.:
Differential expression of LIM domain-only (LMO) genes in the developing mouse inner ear
Gene Expr Patterns
2006
6: 857-863
|
| 31733190 |
DiStasio A et al.:
Nubp2 is required for cranial neural crest survival in the mouse
Dev Biol
2020
458: 189-199
|
| 31985533 |
Kari E et al.:
Genes Implicated in Rare Congenital Inner Ear and Cochleovestibular Nerve Malformations
Ear Hear
2020
41: 983-989
|
| 30455064 |
Ritter KE et al.:
Neural crest contributions to the ear: Implications for congenital hearing disorders
Hear Res
2019
376: 22-32
|
| 25087164 |
Ivanov IS et al. et al.:
Founder p.Arg 446* mutation in the PDHX gene explains over half of cases with congenital lactic acidosis in Roma children
Mol Genet Metab
2014
113: 76-83
|
| 26469318 |
Elkon R et al. et al.:
RFX transcription factors are essential for hearing in mice
Nat Commun
2015
6: 8549
|
| 27503514 |
Piceci F et al.:
Identification of a second HOXA2 nonsense mutation in a family with autosomal dominant non-syndromic microtia and distinctive ear morphology
Clin Genet
2017
91: 774-779
|
| 23775976 |
Brown KK et al.:
HOXA2 haploinsufficiency in dominant bilateral microtia and hearing loss
Hum Mutat
2013
34: 1347-1351
|
| 12761041 |
Hawkins RD et al.:
Gene expression differences in quiescent versus regenerating hair cells of avian sensory epithelia: implications for human hearing and balance disorders
Hum Mol Genet
2003
12: 1261-1272
|
| 14611647 |
Paces-Fessy M et al.:
The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins
Biochem J
2004
378: 353-362
|
| 33140220 |
author information missing
article information missing
|
| 22174793 |
author information missing
article information missing
|
| 12955485 |
author information missing
article information missing
|
| 17452450 |
author information missing
article information missing
|
| 30478191 |
author information missing
article information missing
|
| 34788619 |
author information missing
article information missing
|
| 30456367 |
author information missing
article information missing
|
| 26138117 |
author information missing
article information missing
|
| 9233772 |
author information missing
article information missing
|
| 27799409 |
author information missing
article information missing
|
| 31444330 |
Wu X et al.:
PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing
Nat Commun
2019
10: 3801
|
| 21228182 |
Peppi M et al.:
A corticosteroid-responsive transcription factor, promyelocytic leukemia zinc finger protein, mediates protection of the cochlea from acoustic trauma
J Neurosci
2011
31: 735-741
|
| 33256196 |
Vona B et al.:
The Many Faces of DFNB9: Relating OTOF Variants to Hearing Impairment
|
| 8908241 |
Bernstein JM et al.:
Further observations on the role of the MHC genes and certain hearing disorders
Acta Otolaryngol
1996
116: 666-671
|
| 23408898 |
Di Bonito M et al.:
Assembly of the auditory circuitry by a Hox genetic network in the mouse brainstem
PLoS Genet
2013
9
|
| 33854102 |
Dhukhwa A et al.:
Regulator of G protein signaling 17 represents a novel target for treating cisplatin induced hearing loss
Sci Rep
2021
11: 8116
|
| 30186120 |
Ghosh S et al.:
The Endocannabinoid/Cannabinoid Receptor 2 System Protects Against Cisplatin-Induced Hearing Loss
Front Cell Neurosci
2018
12: 271
|
| 26427583 |
Toal KL et al.:
Audiograms, gap detection thresholds, and frequency difference limens in cannabinoid receptor 1 knockout mice
Hear Res
2016
332: 217-222
|
| 32592712 |
author information missing
Mitochondrial cytopathy with lactic acidosis, carnitine deficiency and DeToni-Fanconi-Debre syndrome
Brain Dev
1986
8: 289-295
|
| 34054423 |
Andresen NS et al.:
Comparison of Age-Related Pigmentary Changes in the Auditory and Vestibular Systems Within Mouse and Human Temporal Bones
Front Neurosci
2021
15
|
| 9584534 |
Hendrick V et al.:
Hormonal changes in the postpartum and implications for postpartum depression.
Psychosomatics
1998
39: 93-101
|
| 20392807 |
Gillies GE et al.:
Estrogen actions in the brain and the basis for differential action in men and women: a case for sex-specific medicines
Pharmacol. Rev.
2010
62: 155-198
|
| 10681512 |
Saville B et al.:
Ligand-, cell-, and estrogen receptor subtype (alpha/beta)-dependent activation at GC-rich (Sp1) promoter elements
J. Biol. Chem.
2000
275: 5379-5387
|
| 16439465 |
Castet A et al.:
Receptor-interacting protein 140 differentially regulates estrogen receptor-related receptor transactivation depending on target genes.
Mol. Endocrinol.
2006
20: 1035-1047
|
| 15670765 |
Sumi D et al.:
Sp1 transcription factor expression is regulated by estrogen-related receptor alpha1.
Biochem. Biophys. Res. Commun.
2005
328: 165-172
|
| 9460651 |
Shigeta H et al.:
The mouse estrogen receptor-related orphan receptor alpha 1: molecular cloning and estrogen responsiveness
J. Mol. Endocrinol.
1997
19: 299-309
|
| 12960079 |
Liu D et al.:
Estrogen stimulates estrogen-related receptor alpha gene expression through conserved hormone response elements.
Endocrinology
2003
144: 4894-4904
|
| 21177257 |
Ren Y et al.:
Parkin degrades estrogen-related receptors to limit the expression of monoamine oxidases
Hum. Mol. Genet.
2011
20: 1074-1083
|
| 16250013 |
Lui WY et al.:
Nectin-2 expression in testicular cells is controlled via the functional cooperation between transcription factors of the Sp1, CREB, and AP-1 families.
J. Cell. Physiol.
2006
207: 144-157
|
| 19465084 |
Stoytcheva ZR et al.:
Transcriptional regulation of mammalian selenoprotein expression.
Biochim. Biophys. Acta
2009
1790: 1429-1440
|
| 8661116 |
Wang Z et al.:
Characterization of the mouse cyclin D3 gene: exon/intron organization and promoter activity.
Genomics
1996
35: 156-163
|
| 17114809 |
Radeff-Huang J et al.:
Tumor necrosis factor-alpha-stimulated cell proliferation is mediated through sphingosine kinase-dependent Akt activation and cyclin D expression.
J. Biol. Chem.
2007
282: 863-870
|
| 18641356 |
Hams E et al.:
Oncostatin M receptor-beta signaling limits monocytic cell recruitment in acute inflammation.
J. Immunol.
2008
181: 2174-2180
|
| 17010207 |
Hong EJ et al.:
Identification of estrogen-regulated genes by microarray analysis of the uterus of immature rats exposed to endocrine disrupting chemicals.
Reprod. Biol. Endocrinol.
2006
4: 49
|
| 17351261 |
Naciff JM et al.:
Uterine temporal response to acute exposure to 17alpha-ethinyl estradiol in the immature rat.
Toxicol. Sci.
2007
97: 467-490
|
| 18174157 |
Hu P et al.:
Estrogen induces estrogen-related receptor alpha gene expression and chromatin structural changes in estrogen receptor (ER)-positive and ER-negative breast cancer cells.
J. Biol. Chem.
2008
283: 6752-6763
|
| 1356762 |
Imataka H et al.:
Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene.
EMBO J.
1992
11: 3663-3671
|
| 3999749 |
Namkung MJ et al.:
Regulation of aromatic oxidation of estradiol-17 beta in maternal hepatic, fetal hepatic and placental tissues: comparative effects of a series of inducing agents.
J. Steroid Biochem.
1985
22: 563-567
|
| 10403529 |
Piscaglia F et al.:
Cellular localization of hepatic cytochrome 1B1 expression and its regulation by aromatic hydrocarbons and inflammatory cytokines.
Biochem. Pharmacol.
1999
58: 157-165
|
| 17942748 |
Boverhof DR et al.:
Inhibition of estrogen-mediated uterine gene expression responses by dioxin.
Mol. Pharmacol.
2008
73: 82-93
|
| 9094091 |
Geum D et al.:
Estrogen-induced cyclin D1 and D3 gene expressions during mouse uterine cell proliferation in vivo: differential induction mechanism of cyclin D1 and D3.
Mol. Reprod. Dev.
1997
46: 450-458
|
| 17555576 |
Fong CJ et al.:
Comparative temporal and dose-dependent morphological and transcriptional uterine effects elicited by tamoxifen and ethynylestradiol in immature, ovariectomized mice.
BMC Genomics
2007
8: 151
|
| 20106945 |
Jennen DG et al.:
Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification.
Toxicol. Sci.
2010
115: 66-79
|
| 20211987 |
Li Y et al.:
Regulation of ERRalpha gene expression by estrogen receptor agonists and antagonists in SKBR3 breast cancer cells: differential molecular mechanisms mediated by g protein-coupled receptor GPR30/GPER-1.
Mol. Endocrinol.
2010
24: 969-980
|
| 19395996 |
Henic E et al.:
Estradiol attenuates EGF-induced rapid uPAR mobilization and cell migration via the G-protein-coupled receptor 30 in ovarian cancer cells.
Int. J. Gynecol. Cancer
2009
19: 214-222
|
| 19553526 |
Abu-Taha M et al.:
Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.
J. Immunol.
2009
183: 1393-1402
|
| 8977427 |
el Meskini R et al.:
Estrogen regulation of peptidylglycine alpha-amidating monooxygenase expression in anterior pituitary gland.
Endocrinology
1997
138: 379-388
|
| 19619570 |
Spink BC et al.:
Long-term estrogen exposure promotes carcinogen bioactivation, induces persistent changes in gene expression, and enhances the tumorigenicity of MCF-7 human breast cancer cells.
Toxicol. Appl. Pharmacol.
2009
240: 355-366
|
| 12522104 |
Schreiber SN et al.:
The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).
J. Biol. Chem.
2003
278: 9013-9018
|
| 16024613 |
Barry JB et al.:
Epidermal growth factor-induced signaling in breast cancer cells results in selective target gene activation by orphan nuclear receptor estrogen-related receptor alpha.
Cancer Res.
2005
65: 6120-6129
|
| 17157980 |
Zhang Z et al.:
Interplay between estrogen-related receptor alpha (ERRalpha) and gamma (ERRgamma) on the regulation of ERRalpha gene expression.
Mol. Cell. Endocrinol.
2007
264: 128-141
|
| 18714402 |
Kroliczak W et al.:
P53-dependent suppression of the human calcyclin gene (S100A6): the role of Sp1 and of NFkappaB.
Acta Biochim. Pol.
2008
55: 559-570
|
| 8668206 |
Naumovski L et al.:
The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M.
Mol. Cell. Biol.
1996
16: 3884-3892
|
| 16166196 |
Luu-The V et al.:
Characterization of type 12 17beta-hydroxysteroid dehydrogenase, an isoform of type 3 17beta-hydroxysteroid dehydrogenase responsible for estradiol formation in women.
Mol. Endocrinol.
2006
20: 437-443
|
| 17668254 |
Li RW et al.:
Canonical pathways and networks regulated by estrogen in the bovine mammary gland.
Funct. Integr. Genomics
2008
8: 55-68
|
| 8262073 |
Weinzierl RO et al.:
Cloning and expression of Drosophila TAFII60 and human TAFII70 reveal conserved interactions with other subunits of TFIID.
EMBO J.
1993
12: 5303-5309
|
| 11595744 |
Warnmark A et al.:
The N-terminal regions of estrogen receptor alpha and beta are unstructured in vitro and show different TBP binding properties.
J. Biol. Chem.
2001
276
|
| 20710045 |
Miki Y et al.:
Intratumoral localization of aromatase and interaction between stromal and parenchymal cells in the non-small cell lung carcinoma microenvironment.
Cancer Res.
2010
70: 6659-6669
|
| 20685874 |
Brown CM et al.:
Production of proinflammatory cytokines and chemokines during neuroinflammation: novel roles for estrogen receptors alpha and beta.
Endocrinology
2010
151: 4916-4925
|
| 9305936 |
Ihn H et al.:
Oncostatin M stimulates transcription of the human alpha2(I) collagen gene via the Sp1/Sp3-binding site.
J. Biol. Chem.
1997
272
|
| 18954559 |
Hao S et al.:
17beta-estradiol suppresses cytotoxicity and proliferative capacity of murine splenic NK1.1+ cells.
Cell. Mol. Immunol.
2008
5: 357-364
|
| 21791181 |
Park HJ et al.:
Characterisation of mouse interferon-induced transmembrane protein-1 gene expression in the mouse uterus during the oestrous cycle and pregnancy.
Reprod. Fertil. Dev.
2011
23: 798-808
|
| 21182205 |
Tarallo R et al.:
Identification of proteins associated with ligand-activated estrogen receptor alpha in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.
Proteomics
2011
11: 172-179
|
| 15001666 |
Bourdeau V et al.:
Genome-wide identification of high-affinity estrogen response elements in human and mouse.
Mol. Endocrinol.
2004
18: 1411-1427
|
| 16636675 |
Stevens TA et al.:
BARX2 and estrogen receptor-alpha (ESR1) coordinately regulate the production of alternatively spliced ESR1 isoforms and control breast cancer cell growth and invasion.
Oncogene
2006
25: 5426-5435
|
| 15514030 |
Naumovski L et al.:
The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M.
Mol. Cell. Biol.
1996
16: 3884-3892
|
| 7809597 |
Thut CJ et al.:
p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60.
Science
1995
267: 100-104
|
| 17395694 |
Levy N et al.:
Multiple transcription factor elements collaborate with estrogen receptor alpha to activate an inducible estrogen response element in the NKG2E gene.
Endocrinology
2007
148: 3449-3458
|
| 16687914 |
Bagchi MK et al.:
Control of uterine cell proliferation and differentiation by C/EBPbeta: functional implications for establishment of early pregnancy.
Cell Cycle
2006
5: 922-925
|
| 18852215 |
Rotinen M et al.:
Estradiol induces type 8 17beta-hydroxysteroid dehydrogenase expression: crosstalk between estrogen receptor alpha and C/EBPbeta.
J. Endocrinol.
2009
200: 85-92
|
| 10438527 |
Wu SY et al.:
Isolation of mouse TFIID and functional characterization of TBP and TFIID in mediating estrogen receptor and chromatin transcription.
J. Biol. Chem.
1999
274
|
| 9886828 |
Xie W et al.:
Estrogen induces adenosine deaminase gene expression in MCF-7 human breast cancer cells: role of estrogen receptor-Sp1 interactions.
Endocrinology
1999
140: 219-227
|
| 12482873 |
Despouy G et al.:
Cyclin D3 is a cofactor of retinoic acid receptors, modulating their activity in the presence of cellular retinoic acid-binding protein II.
J. Biol. Chem.
2003
278: 6355-6362
|
| 15289156 |
Moggs JG et al.:
The need to decide if all estrogens are intrinsically similar.
Environ. Health Perspect.
2004
112: 1137-1142
|
| 20883782 |
Ijichi N et al.:
Estrogen-related receptor gamma modulates cell proliferation and estrogen signaling in breast cancer.
J. Steroid Biochem. Mol. Biol.
2011
123: 1-7
|
| 21182203 |
Nassa G et al.:
A large set of estrogen receptor beta-interacting proteins identified by tandem affinity purification in hormone-responsive human breast cancer cell nuclei.
Proteomics
2011
11: 159-165
|
| 12748190 |
Lohr K et al.:
p21/CDKN1A mediates negative regulation of transcription by p53.
J. Biol. Chem.
2003
278
|
| 16732327 |
Lin YT et al.:
Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control.
Oncogene
2006
25: 6901-6914
|
| 12706304 |
Schultz JR et al.:
Estrogen receptor alpha and Sp1 regulate progesterone receptor gene expression.
Mol. Cell. Endocrinol.
2003
201: 165-175
|
| 2328727 |
Kastner P et al.:
Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.
EMBO J.
1990
9: 1603-1614
|
| 21371262 |
Moriyama T et al.:
Targeted disruption of one of the importin alpha family members leads to female functional incompetence in delivery.
FEBS J.
2011
278: 1561-1572
|
| 14674758 |
Belyaeva OV et al.:
Properties of short-chain dehydrogenase/reductase RalR1: characterization of purified enzyme, its orientation in the microsomal membrane, and distribution in human tissues and cell lines.
Biochemistry
2003
42
|
| 15205379 |
Li XH et al.:
Estrogen directly induces expression of retinoic acid biosynthetic enzymes, compartmentalized between the epithelium and underlying stromal cells in rat uterus.
Endocrinology
2004
145: 4756-4762
|
| 2162635 |
Cavey MT et al.:
In vitro binding of retinoids to the nuclear retinoic acid receptor alpha.
Anal. Biochem.
1990
186: 19-23
|
| 19533843 |
Nagasaki S et al.:
Transcriptional regulation of 17beta-hydroxysteroid dehydrogenase type 12 by SREBP-1.
Mol. Cell. Endocrinol.
2009
307: 163-168
|
| 10873660 |
Ikeda K et al.:
Promoter analysis and chromosomal mapping of human EBAG9 gene.
Biochem. Biophys. Res. Commun.
2000
273: 654-660
|
| 17418098 |
Nakajima A et al.:
Ligand-dependent transcription of estrogen receptor alpha is mediated by the ubiquitin ligase EFP.
Biochem. Biophys. Res. Commun.
2007
357: 245-251
|
| 19995977 |
Zadran S et al.:
17-Beta-estradiol increases neuronal excitability through MAP kinase-induced calpain activation
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 9294175 |
Trowbridge JM et al.:
Regulation of estrogen receptor transcriptional enhancement by the cyclin A/Cdk2 complex
Proc. Natl. Acad. Sci. U.S.A.
1997
94
|
| 9498464 |
Goldberg AD et al.:
Distinct factors control histone variant H3.3 localization at specific genomic regions.
Cell
2010
140: 678-691
|
| 12603854 |
Kanda N et al.:
17beta-estradiol inhibits the production of interferon-induced protein of 10 kDa by human keratinocytes.
J. Invest. Dermatol.
2003
120: 411-419
|
| 18497089 |
Lehmann L et al.:
Gene expression of 17beta-estradiol-metabolizing isozymes: comparison of normal human mammary gland to normal human liver and to cultured human breast adenocarcinoma cells.
Adv. Exp. Med. Biol.
2008
617: 617-624
|
| 16474171 |
Buterin T et al.:
Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoestrogens in breast cancer cells
Carcinogenesis
2006
27: 1567-1578
|
| 19561196 |
Zhou R et al.:
Senescence delay and repression of p16INK4a by Lsh via recruitment of histone deacetylases in human diploid fibroblasts
Nucleic Acids Res.
2009
37: 5183-5196
|
| 11782371 |
Fan S et al.:
p300 Modulates the BRCA1 inhibition of estrogen receptor activity.
Cancer Res.
2002
62: 141-151
|
| 11163245 |
Seo SB et al.:
Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein.
Cell
2001
104: 119-130
|
| 11689448 |
Kim MY et al.:
A role for coactivators and histone acetylation in estrogen receptor alpha-mediated transcription initiation.
EMBO J.
2001
20: 6084-6094
|
| 11973642 |
Sers C et al.:
The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNgamma-induced cell death in human ovarian carcinoma cells.
Oncogene
2002
21: 2829-2839
|
| 11893774 |
Jones DR et al.:
Estrogen receptor-mediated repression of human hepatic lipase gene transcription.
J. Lipid Res.
2002
43: 383-391
|
| 11598016 |
Fojas de Borja P et al.:
Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription
EMBO J.
2001
20: 5737-5747
|
| 11805140 |
Heaney AP et al.:
Functional role of estrogen in pituitary tumor pathogenesis.
J. Clin. Invest.
2002
109: 277-283
|
| 17353909 |
Tong Y et al.:
Pituitary tumor transforming gene interacts with Sp1 to modulate G1/S cell phase transition.
Oncogene
2007
26: 5596-5605
|
| 17825481 |
DeNardo DG et al.:
Estrogen receptor DNA binding is not required for estrogen-induced breast cell growth.
Mol. Cell. Endocrinol.
2007
277: 13-25
|
| 12615712 |
Xue L et al.:
Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits.
Cancer Res.
2003
63: 980-986
|
| 16469747 |
Liu W et al.:
Estrogen receptor-alpha binds p53 tumor suppressor protein directly and represses its function.
J. Biol. Chem.
2006
281: 9837-9840
|
| 19106611 |
Liu P et al.:
Replication licensing promotes cyclin D1 expression and G1 progression in untransformed human cells
Cell Cycle
2009
8: 125-136
|
| 17950954 |
Aenlle KK et al.:
Estrogen effects on cognition and hippocampal transcription in middle-aged mice
Neurobiol. Aging
2009
30: 932-945
|
| 12408966 |
Marzluff WF et al.:
The human and mouse replication-dependent histone genes
Genomics
2002
80: 487-498
|
| 1916825 |
Albig W et al.:
Isolation and characterization of two human H1 histone genes within clusters of core histone genes
Genomics
1991
10: 940-948
|
| 17361106 |
Maine GN et al.:
COMMD proteins and the control of the NF kappa B pathway
Cell Cycle
2007
6: 672-676
|
| 12764024 |
Rodriguez-Pascual F et al.:
Functional cooperation between Smad proteins and activator protein-1 regulates transforming growth factor-beta-mediated induction of endothelin-1 expression
Circ. Res.
2003
92: 1288-1295
|
| 2169352 |
Yang-Yen HF et al.:
Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction
Cell
1990
62: 1205-1215
|
| 17675297 |
Butler MP et al.:
Kinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases
J. Biol. Chem.
2007
282
|
| 9159119 |
Scully R et al.:
BRCA1 is a component of the RNA polymerase II holoenzyme
Proc. Natl. Acad. Sci. U.S.A.
1997
94: 5605-5610
|
| 10725406 |
Schlegel BP et al.:
BRCA1 interaction with RNA polymerase II reveals a role for hRPB2 and hRPB10alpha in activated transcription
Proc. Natl. Acad. Sci. U.S.A.
2000
97: 3148-3153
|
| 11096118 |
Vig E et al.:
SIMPL is a tumor necrosis factor-specific regulator of nuclear factor-kappaB activity
J. Biol. Chem.
2001
276: 7859-7866
|
| 10469655 |
Heissmeyer V et al.:
NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes
EMBO J.
1999
18: 4766-4778
|
| 8290595 |
Ray A et al.:
Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor
Proc. Natl. Acad. Sci. U.S.A.
1994
91: 752-756
|
| 14743216 |
Bouwmeester T et al.:
A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway
Nat. Cell Biol.
2004
6: 97-105
|
| 1827992 |
Walker JE et al.:
Identification of the subunits of F1F0-ATPase from bovine heart mitochondria
Biochemistry
1991
30: 5369-5378
|
| 20961850 |
Bryde S et al.:
CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery
J. Biol. Chem.
2010
285
|
| 19270718 |
Geng H et al.:
Phosphorylation of NF-kappaB p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal elimination
EMBO Rep.
2009
10: 381-386
|
| 11044375 |
Muzio M et al.:
Toll-like receptor family and signalling pathway
Biochem. Soc. Trans.
2000
28: 563-566
|
| 21149447 |
Joshi S et al.:
Essential role for Mnk kinases in type II interferon (IFNgamma) signaling and its suppressive effects on normal hematopoiesis
J. Biol. Chem.
2011
286: 6017-6026
|
| 12485619 |
Wajant H et al.:
Non-apoptotic Fas signaling
Cytokine Growth Factor Rev.
2003
14: 53-66
|
| 22286099 |
Foxler DE et al.:
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
Nat. Cell Biol.
2012
14: 201-208
|
| 20856203 |
Pardali E et al.:
Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma
Oncogene
2011
30: 334-345
|
| 9525694 |
Wrana JL et al.:
TGF-beta receptors and signalling mechanisms
Miner Electrolyte Metab
1998
24: 120-130
|
| 12897141 |
Scheper GC et al.:
The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localization
Mol. Cell. Biol.
2003
23: 5692-5705
|
| 15761153 |
Barrios-Rodiles M et al.:
High-throughput mapping of a dynamic signaling network in mammalian cells
Science
2005
307: 1621-1625
|
| 21670145 |
Kang JH et al.:
Complex formation and interactions between transcription factors essential for human prolactin receptor gene transcription
Mol. Cell. Biol.
2011
31: 3208-3222
|
| 15026085 |
Gutzman JH et al.:
Endogenous human prolactin and not exogenous human prolactin induces estrogen receptor alpha and prolactin receptor expression and increases estrogen responsiveness in breast cancer cells
J. Steroid Biochem. Mol. Biol.
2004
88: 69-77
|
| 16228000 |
author information missing
article information missing
|
| 19422879 |
Liao CS et al.:
Regulation of AKR1B1 by thyroid hormone and its receptors
Mol. Cell. Endocrinol.
2009
307: 109-117
|
| 27121597 |
Cousins FL et al.:
Androgens regulate scarless repair of the endometrial wound in a mouse model of menstruation
FASEB J.
2016
30: 2802-2811
|
| 24495597 |
Velarde MC et al.:
Mitochondrial and sex steroid hormone crosstalk during aging
Longev Healthspan
2014
3: 2
|
| 15283675 |
Rice GI et al.:
Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism
Biochem. J.
2004
383: 45-51
|
| 10969042 |
Donoghue M et al.:
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
Circ. Res.
2000
87: E1-E9
|
| 23392115 |
Grobe N et al.:
Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry
Am. J. Physiol.
2013
304: C945-C953
|
| 20689271 |
Schulman IH et al.:
Altered renal expression of angiotensin II receptors, renin receptor, and ACE-2 precede the development of renal fibrosis in aging rats
Am. J. Nephrol.
2010
32: 249-261
|
| 24332999 |
Patel VB et al.:
Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: a positive feedback mechanism in the RAS
J. Mol. Cell. Cardiol.
2014
66: 167-176
|
| 26697984 |
Wilson BA et al.:
Evidence for a mitochondrial angiotensin-(1-7) system in the kidney
Am. J. Physiol. Renal Physiol.
2016
310: F637-F645
|
| 26709511 |
Murugan D et al.:
Angiotensin 1-7 Protects against Angiotensin II-Induced Endoplasmic Reticulum Stress and Endothelial Dysfunction via Mas Receptor
PLoS ONE
2015
10
|
| 25225202 |
Deshotels MR et al.:
Angiotensin II mediates angiotensin converting enzyme type 2 internalization and degradation through an angiotensin II type I receptor-dependent mechanism
Hypertension
2014
64: 1368-1375
|
| 8351287 |
Hong-Brown LQ et al.:
Regulation of the angiotensinogen gene by estrogens in rat liver and different brain regions
Proc. Soc. Exp. Biol. Med.
1993
203: 467-473
|
| 26562171 |
Mompeon A et al.:
Estradiol, acting through ERalpha, induces endothelial non-classic renin-angiotensin system increasing angiotensin 1-7 production
Mol. Cell. Endocrinol.
2016
422: 1-8
|
| 24055033 |
Matsui K et al.:
Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin beta gene promoter
Biochem Biophys Res Commun
2013
440: 184-189
|
| 25350068 |
Fernandez LP et al.:
Thyroid transcription factors in development, differentiation and disease
Nat Rev Endocrinol
2015
11: 29-42
|
| 28060725 |
Liu S et al.:
Identification and characterization of novel PAX8 mutations in Congenital Hypothyroidism(CH) in a Chinese population
Oncotarget
2017
8: 8707-8716
|
| 11069301 |
Pasca di Magliano M et al.:
Pax8 has a key role in thyroid cell differentiation
Proc Natl Acad Sci U S A
2000
97
|
| 11453662 |
Sellitti DF et al.:
Thyroglobulin increases cell proliferation and suppresses Pax-8 in mesangial cells
Biochem Biophys Res Commun
2001
285: 795-799
|
| 30209975 |
Yau WW et al.:
Thyroid hormone (T3) stimulates brown adipose tissue activation via mitochondrial biogenesis and MTOR-mediated mitophagy
Autophagy
2019
15: 131-150
|
| 15966508 |
Manetti L et al.:
Thyroid function differently affects serum cystatin C and creatinine concentrations
J Endocrinol Invest
2005
28: 346-349
|
| 30886364 |
Citterio CE et al.:
The role of thyroglobulin in thyroid hormonogenesis
Nat Rev Endocrinol
2019
15: 323-338
|
| 28153798 |
Carvalho DP et al.:
Thyroid hormone biosynthesis and release
Mol Cell Endocrinol
2017
458: 6-15
|
| 1568764 |
Chen YF et al.:
Androgen-dependent angiotensinogen and renin messenger RNA expression in hypertensive rats
Hypertension
1992
19: 456-463
|
| 3553481 |
author information missing
Renin relationship to sex, race and age in a normotensive population
J Hypertens Suppl
1986
4: S387-S389
|
| 25659489 |
Sullivan JC et al.:
Differences in angiotensin (1-7) between men and women
Am J Physiol Heart Circ Physiol
2015
308
|
| 32410690 |
Sward P et al.:
Age and sex differences in soluble ACE2 may give insights for COVID-19
Crit Care
2020
24: 221
|
| 21321306 |
Gonzalez AA et al.:
Soluble form of the (pro)renin receptor is augmented in the collecting duct and urine of chronic angiotensin II-dependent hypertensive rats
Hypertension
2011
57: 859-864
|
| 12684512 |
Suzuki F et al.:
Human prorenin has gate and handle regions for its non-proteolytic activation
J Biol Chem
2003
278
|
| 17569611 |
Nurun NA et al.:
Role of handle region of prorenin prosegment in the non-proteolytic activation of prorenin by binding to membrane anchored (pro)renin receptor
Front Biosci
2007
12: 4810-4817
|
| 28013223 |
Nakagawa T et al.:
Site-1 protease is required for the generation of soluble (pro)renin receptor
J Biochem
2017
161: 369-379
|
| 29056916 |
Zhang L et al.:
Inhibition of (pro)renin Receptor Contributes to Renoprotective Effects of Angiotensin II Type 1 Receptor Blockade in Diabetic Nephropathy
Front Physiol
2017
8: 758
|
| 32698840 |
Kornilov SA et al.:
Plasma levels of soluble ACE2are associated with sex, Metabolic Syndrome, and its biomarkers in a large cohort, pointing to a possible mechanism for increased severity in COVID-19
Crit Care
2020
24: 452
|
| 21068237 |
Shulla A et al.:
A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry
J Virol
2011
85: 873-882
|
| 10585461 |
Sinn PL et al.:
Highly regulated cell type-restricted expression of human renin in mice containing 140- or 160-kilobase pair P1 phage artificial chromosome transgenes
J Biol Chem
1999
274
|
| 28175301 |
Guo T et al.:
Mutations in MSH5 in primary ovarian insufficiency
Hum Mol Genet
2017
26: 1452-1457
|
| 27807919 |
author information missing
article information missing
|
| 24346624 |
author information missing
article information missing
|
| 12393952 |
Lavery WL et al.:
Increased expression of the S25 ribosomal protein gene occurs during ageing of the rat liver
Gerontology
2002
48: 369-373
|
| 18371188 |
Rodenburg W et al.:
Impaired barrier function by dietary fructo-oligosaccharides (FOS) in rats is accompanied by increased colonic mitochondrial gene expression
BMC Genomics
2008
9: 144
|
| 23383273 |
Yu CC et al.:
VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells
PLoS ONE
2013
8
|
| 25073467 |
Li T et al.:
Bile acid signaling in metabolic disease and drug therapy
Pharmacol. Rev.
2014
66: 948-983
|
| 28894110 |
Menni C et al.:
Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women
Sci Rep
2017
7: 11079
|
| 21493887 |
Kasaikina MV et al.:
Dietary selenium affects host selenoproteome expression by influencing the gut microbiota
FASEB J.
2011
25: 2492-2499
|
| 29057986 |
Pallister T et al.:
Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome
Sci Rep
2017
7: 13670
|
| 19891605 |
Pero RW et al.:
Health consequences of catabolic synthesis of hippuric acid in humans
Curr Clin Pharmacol
2010
5: 67-73
|
| 28765282 |
Bush KT et al.:
The drug transporter OAT3 (SLC22A8) and endogenous metabolite communication via the gut-liver-kidney axis
J. Biol. Chem.
2017
292
|
| 12771329 |
Gonthier MP et al.:
Chlorogenic acid bioavailability largely depends on its metabolism by the gut microflora in rats
J. Nutr.
2003
133: 1853-1859
|
| 28069752 |
Blacher E et al.:
Microbiome-Modulated Metabolites at the Interface of Host Immunity
J. Immunol.
2017
198: 572-580
|
| 27320064 |
Wahlstrom A et al.:
Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism
Cell Metab.
2016
24: 41-50
|
| 29731746 |
Zhao X et al.:
Response of Gut Microbiota to Metabolite Changes Induced by Endurance Exercise
Front Microbiol
2018
9: 765
|
| 23563705 |
Koeth RA et al. et al.:
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis
Nat. Med.
2013
19: 576-585
|
| 23563705 |
Koeth RA et al.:
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis
Nat. Med.
2013
19: 576-585
|
| 29572891 |
Caussy C et al. et al.:
Link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fibrosis in NAFLD
|
| 3216284 |
Nakamura J et al.:
Hydrolysis of salicyluric acid in intestinal microorganisms and prolonged blood concentration of salicylic acid following rectal administration of salicyluric acid in rats
J. Pharmacobio-dyn.
1988
11: 625-629
|
| 3834062 |
et al.:
Hydrolysis of salicyluric acid in rabbit intestinal microorganisms
J. Pharmacobio-dyn.
1985
8: 989-995
|
| 30183376 |
Houghton MJ et al.:
Gut microbiome catabolites as novel modulators of muscle cell glucose metabolism
|
| 28360096 |
Barton W et al.:
The microbiome of professional athletes differs from that of more sedentary subjects in composition and particularly at the functional metabolic level
Gut
2018
67: 625-633
|
| 27779624 |
Frye RE et al.:
Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
Transl Psychiatry
2016
6: e927
|
| 29213261 |
Rodrigues RR et al.:
Antibiotic-Induced Alterations in Gut Microbiota Are Associated with Changes in Glucose Metabolism in Healthy Mice
Front Microbiol
2017
8: 2306
|
| 30354823 |
Zhang ZY et al.:
Branched-Chain Amino Acids as Critical Switches in Health and Disease
Hypertension
2018
72: 1012-1022
|
| 30030441 |
Zarrinpar A et al.:
Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism
Nat Commun
2018
9: 2872
|
| 24997027 |
Lyte M et al.:
Microbial endocrinology and the microbiota-gut-brain axis
Adv. Exp. Med. Biol.
2014
817: 3-24
|
| 29620942 |
Zheng X et al. et al.:
Food withdrawal alters the gut microbiota and metabolome in mice
FASEB J.
2018
32: 4878-4888
|
| 30233586 |
Lebovitz Y et al.:
Emerging Developments in Microbiome and Microglia Research: Implications for Neurodevelopmental Disorders
Front Immunol
2018
9: 1993
|
| 23029553 |
Donohoe DR et al.:
Microbial regulation of glucose metabolism and cell-cycle progression in mammalian colonocytes
PLoS ONE
2012
7
|
| 29143823 |
Wilck N et al. et al.:
Salt-responsive gut commensal modulates TH17 axis and disease
Nature
2017
551: 585-589
|
| 9245571 |
Lyte M et al.:
Neuroendocrine-bacterial interactions in a neurotoxin-induced model of trauma
J. Surg. Res.
1997
70: 195-201
|
| 30231992 |
Sharma V et al.:
Mannose Alters Gut Microbiome, Prevents Diet-Induced Obesity, and Improves Host Metabolism
Cell Rep
2018
24: 3087-3098
|
| 23279728 |
Aziz Q et al.:
Gut microbiota and gastrointestinal health: current concepts and future directions
Neurogastroenterol. Motil.
2013
25: 4-15
|
| 21508958 |
Arumugam M et al. et al.:
Enterotypes of the human gut microbiome
Nature
2011
473: 174-180
|
| 29454749 |
Gentile CL et al.:
The gut microbiota at the intersection of diet and human health
Science
2018
362: 776-780
|
| 29804833 |
Olson CA et al.:
The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet
Cell
2018
173: 1728-1741.e13
|
| 30619249 |
Martin-Gallausiaux C et al.:
Butyrate Produced by Commensal Bacteria Down-Regulates Indolamine 2,3-Dioxygenase 1 (IDO-1) Expression via a Dual Mechanism in Human Intestinal Epithelial Cells
Front Immunol
2018
9: 2838
|
| 28625867 |
Postler TS et al.:
Understanding the Holobiont: How Microbial Metabolites Affect Human Health and Shape the Immune System
Cell Metab.
2017
26: 110-130
|
| 23408055 |
Zheng X et al. et al.:
Melamine-induced renal toxicity is mediated by the gut microbiota
Sci Transl Med
2013
5: 172ra22
|
| 29451186 |
Cao YN et al.:
Lactobacillus acidophilus and Bifidobacterium longum supernatants upregulate the serotonin transporter expression in intestinal epithelial cells
Saudi J Gastroenterol
2018
24: 59-66
|
| 15371263 |
Sarkar C et al.:
Dopamine in vivo inhibits VEGF-induced phosphorylation of VEGFR-2, MAPK, and focal adhesion kinase in endothelial cells
Am J Physiol Heart Circ Physiol
2004
287
|
| 31794424 |
Xu P et al.:
Stomach gastrin is regulated by sodium via PPAR-alpha and dopamine D1 receptor
J Mol Endocrinol
2020
64: 53-65
|
| 33399851 |
Sharma RK et al.:
Angiotensin-converting enzyme 2 and COVID-19 in cardiorenal diseases
Clin Sci (Lond)
2021
135: 1-17
|
| 12091339 |
Reddy VA et al.:
Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: possible role in lineage commitment decisions.
Blood
2002
100: 483-490
|
| 17671233 |
Yeamans C et al.:
C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment.
Blood
2007
110: 3136-3142
|
| 10397723 |
Wang X et al.:
C/EBPalpha bypasses granulocyte colony-stimulating factor signals to rapidly induce PU.1 gene expression, stimulate granulocytic differentiation, and limit proliferation in 32D cl3 myeloblasts.
Blood
1999
94: 560-571
|
| 12949251 |
Kummalue T et al.:
Cross-talk between regulators of myeloid development: C/EBPalpha binds and activates the promoter of the PU.1 gene.
J. Leukoc. Biol.
2003
74: 464-470
|
| 20924107 |
Lidonnici MR et al.:
Expression of the transcriptional repressor Gfi-1 is regulated by C/EBP{alpha} and is involved in its proliferation and colony formation-inhibitory effects in p210BCR/ABL-expressing cells.
Cancer Res.
2010
70: 7949-7959
|
| 17197705 |
Dahl R et al.:
The transcriptional repressor GFI-1 antagonizes PU.1 activity through protein-protein interaction.
J. Biol. Chem.
2007
282: 6473-6483
|
| 19491391 |
Chou ST et al.:
Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate.
Blood
2009
114: 983-994
|
| 12857954 |
Grass JA et al.:
GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling.
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 8811-8816
|
| 9482838 |
Blobel GA et al.:
CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation.
Proc. Natl. Acad. Sci. U.S.A.
1998
95: 2061-2066
|
| 14559995 |
Rekhtman N et al.:
PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation.
Mol. Cell. Biol.
2003
23: 7460-7474
|
| 10411939 |
Zhang P et al.:
Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1.
Proc. Natl. Acad. Sci. U.S.A.
1999
96: 8705-8710
|
| 11023493 |
Zhang P et al.:
PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding.
Blood
2000
96: 2641-2648
|
| 15920470 |
Hong W et al.:
FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1.
EMBO J.
2005
24: 2367-2378
|
| 12556498 |
Starck J et al.:
Functional cross-antagonism between transcription factors FLI-1 and EKLF.
Mol. Cell. Biol.
2003
23: 1390-1402
|
| 12730669 |
Wang QF et al.:
Cell cycle inhibition mediated by the outer surface of the C/EBPalpha basic region is required but not sufficient for granulopoiesis.
Oncogene
2003
22: 2548-2557
|
| 16923394 |
Laslo P et al.:
Multilineage transcriptional priming and determination of alternate hematopoietic cell fates.
Cell
2006
126: 755-766
|
| 8668170 |
Svaren J et al.:
NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli.
Mol. Cell. Biol.
1996
16: 3545-3553
|
| 21163928 |
Huang X et al.:
Regulated expression of microRNAs-126/126* inhibits erythropoiesis from human embryonic stem cells.
Blood
2011
117: 2157-2165
|
| 12867998 |
Zeuner A et al.:
Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1.
Cell Death Differ.
2003
10: 905-913
|
| 12867998 |
Zeuner A et al.:
Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1
Cell Death Differ.
2003
8: 905-913
|
| 1396592 |
Aplan PD et al.:
The SCL gene product: a positive regulator of erythroid differentiation.
EMBO J.
1992
11: 4073-4081
|
| 10381501 |
Gregory T et al.:
GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression.
Blood
1999
94: 87-96
|
| 12446786 |
Rangatia J et al.:
Downregulation of c-Jun expression by transcription factor C/EBPalpha is critical for granulocytic lineage commitment.
Mol. Cell. Biol.
2002
22: 8681-8694
|
| 20720003 |
Kimura A et al.:
The gene encoding the hematopoietic stem cell regulator CCN3/NOV is under direct cytokine control through the transcription factors STAT5A/B.
J. Biol. Chem.
2010
285
|
| 17463287 |
Gupta R et al.:
NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells.
Science
2007
316: 590-593
|
| 20711984 |
Fleury M et al.:
Mpl receptor defect leads to earlier appearance of hematopoietic cells/hematopoietic stem cells in the Aorta-Gonad-Mesonephros region, with increased apoptosis.
Int. J. Dev. Biol.
2010
54: 1067-1074
|
| 19187226 |
Kaneko K et al.:
Hypoxia induces erythroid-specific 5-aminolevulinate synthase expression in human erythroid cells through transforming growth factor-beta signaling
FEBS J.
2009
276: 1370-1382
|
| 22267605 |
Ku CJ et al.:
GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry
Blood
2012
119: 2242-2251
|
| 22006020 |
Chan WI et al.:
The transcriptional coactivator Cbp regulates self-renewal and differentiation in adult hematopoietic stem cells
Mol. Cell. Biol.
2011
31: 5046-5060
|
| 22983707 |
Glasmacher E et al.:
A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes
Science
2012
338: 975-980
|
| 24014243 |
Wang T et al.:
The control of hematopoietic stem cell maintenance, self-renewal, and differentiation by Mysm1-mediated epigenetic regulation
Blood
2013
122: 2812-2822
|
| 18341635 |
Cerecedo D et al.:
beta-Dystroglycan modulates the interplay between actin and microtubules in human-adhered platelets
Br. J. Haematol.
2008
141: 517-528
|
| 11756159 |
Kirito K et al.:
Identification of the human erythropoietin receptor region required for Stat1 and Stat3 activation
Blood
2002
99: 102-110
|
| 8108116 |
Care A et al.:
c-fes expression in ontogenetic development and hematopoietic differentiation
Oncogene
1994
9: 739-747
|
| 18805794 |
Montoya-Durango DE et al.:
Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor
J. Biol. Chem.
2008
283
|
| 8887656 |
Grimes HL et al.:
The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal
Mol. Cell. Biol.
1996
16: 6263-6272
|
| 12874834 |
McGhee L et al.:
Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism
J. Cell. Biochem.
2003
89: 1005-1018
|
| 16688220 |
Vassen L et al.:
Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin
EMBO J.
2006
25: 2409-2419
|
| 9058808 |
Suzuki Y et al.:
HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases
J. Immunol.
1997
158: 2736-2744
|
| 23021219 |
Yang H et al.:
TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation
Cell
2012
151: 111-122
|
| 24674754 |
Pioli PD et al.:
Snail transcription factors in hematopoietic cell development: a model of functional redundancy
Exp. Hematol.
2014
42: 425-430
|
| 16735694 |
Hale JS et al.:
Transcriptional control of Pactolus: evidence of a negative control region and comparison with its evolutionary paralogue, CD18 (beta2 integrin)
J. Leukoc. Biol.
2006
80: 383-398
|
| 22531927 |
Dahlem T et al.:
Overexpression of Snai3 suppresses lymphoid- and enhances myeloid-cell differentiation
Eur. J. Immunol.
2012
42: 1038-1043
|
| 30573509 |
Noy PJ et al. et al.:
Tspan18 is a novel regulator of the Ca(2+) channel Orai1 and von Willebrand factor release in endothelial cells
Haematologica
2019
104: 1892-1905
|
| 29700810 |
D'Amours G et al. et al.:
Refining the phenotype associated with biallelic DNAJC21 mutations
Clin. Genet.
2018
94: 252-258
|
| 22246507 |
Zelinski T et al.:
ABCG2 null alleles define the Jr(a-) blood group phenotype
Nat. Genet.
2012
44: 131-132
|
| 23937567 |
Terao C et al.:
Quantitative variation in plasma angiotensin-I converting enzyme activity shows allelic heterogeneity in the ABO blood group locus
Ann. Hum. Genet.
2013
77: 465-471
|
| 32609874 |
Leaf RK et al.:
ABO Phenotype and Death in Critically Ill Patients with COVID-19
|
| 32420611 |
O'Sullivan JM et al.:
More on Association between ABO blood groups and risk of SARS-CoV-2 pneumonia
Br. J. Haematol.
2020
190: 27-28
|
| 22773607 |
Pelucchi S et al. et al.:
CYBRD1 as a modifier gene that modulates iron phenotype in HFE p.C282Y homozygous patients
Haematologica
2012
97: 1818-1825
|
| 29096812 |
Weitz JI et al.:
A Test in Context: D-Dimer
J Am Coll Cardiol
2017
70: 2411-2420
|
| 28228446 |
Kattula S et al.:
Fibrinogen and Fibrin in Hemostasis and Thrombosis
Arterioscler Thromb Vasc Biol
2017
37: e13-e21
|
| 2966802 |
Beckmann R et al.:
Plasminogen activation by tissue plasminogen activator in the presence of stimulating CNBr fragment FCB-2 of fibrinogen is a two-phase reaction. Kinetic analysis of the initial phase of slow plasmin formation
J Biol Chem
1988
263: 7176-7180
|
| 6539333 |
author information missing
Isolation and characterization of a urokinase-type plasminogen activator (Mr = 54,000) from cultured human endothelial cells indistinguishable from urinary urokinase
J Biol Chem
1984
259: 7198-7205
|
| 31309890 |
Urano T et al.:
Recognition of Plasminogen Activator Inhibitor Type 1 as the Primary Regulator of Fibrinolysis
Curr Drug Targets
2019
20: 1695-1701
|
| 26411319 |
Zhu Y et al.:
Antithrombin, an Important Inhibitor in Blood Clots
Curr Top Med Chem
2016
16: 666-674
|
| 31424116 |
Freeberg MAT et al.:
Transcriptomic Analysis of Cellular Pathways in Healing Flexor Tendons of Plasminogen Activator Inhibitor 1 (PAI-1/Serpine1) Null Mice
J Orthop Res
2020
38: 43-58
|
| 19464229 |
Manthey HD et al.:
Complement component 5a (C5a)
Int J Biochem Cell Biol
2009
41: 2114-2117
|
| 11460477 |
Ritchie H et al.:
Characterization of crosslinking sites in fibrinogen for plasminogen activator inhibitor 2 (PAI-2)
Ann N Y Acad Sci
2001
936: 215-218
|
| 18063751 |
Law RH et al.:
X-ray crystal structure of the fibrinolysis inhibitor alpha2-antiplasmin
Blood
2008
111: 2049-2052
|
| 10075865 |
Lu PD et al.:
The receptor for the globular heads of C1q, gC1q-R, binds to fibrinogen/fibrin and impairs its polymerization
Clin Immunol
1999
90: 360-367
|
| 24636778 |
author information missing
Thrombin promotes fibronectin secretion by bone marrow mesenchymal stem cells via the protease-activated receptor mediated signalling pathways
Stem Cell Res Ther
2014
5: 36
|
| 22613725 |
Leksa V et al.:
Dissecting mannose 6-phosphate-insulin-like growth factor 2 receptor complexes that control activation and uptake of plasminogen in cells
J Biol Chem
2012
287
|
| 22536427 |
Hess K et al.:
Effects of MASP-1 of the complement system on activation of coagulation factors and plasma clot formation
PLoS One
2012
7
|
| 11907111 |
Matsushita M et al.:
Activation of the lectin complement pathway by H-ficolin (Hakata antigen)
J Immunol
2002
168: 3502-3506
|
| 6197764 |
author information missing
Pregnancy-associated plasma protein-A (PAPP-A) inhibits thrombin-induced coagulation of plasma
Thromb Res
1983
32: 45-55
|
| 21523796 |
Tarrats N et al.:
Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis
Hepatology
2011
54: 319-327
|
| 20218879 |
Gao S et al.:
Dual interference with novel genes mfgl2 and mTNFR1 ameliorates murine hepatitis virus type 3-induced fulminant hepatitis in BALB/cJ mice
Hum Gene Ther
2010
21: 969-977
|
| 25867016 |
Fan NK et al.:
Experimental and imaging techniques for examining fibrin clot structures in normal and diseased states
|
| 18456010 |
Krarup A et al.:
The action of MBL-associated serine protease 1 (MASP1) on factor XIII and fibrinogen
Biochim Biophys Acta
2008
1784: 1294-1300
|
| 11313261 |
Sica GL et al.:
RELT, a new member of the tumor necrosis factor receptor superfamily, is selectively expressed in hematopoietic tissues and activates transcription factor NF-kappaB
Blood
2001
97: 2702-2707
|
| 19940264 |
Moriya J et al.:
Inhibition of semaphorin as a novel strategy for therapeutic angiogenesis
Circ Res
2010
106: 391-398
|
| 20385769 |
Sakurai A et al.:
Semaphorin 3E initiates antiangiogenic signaling through plexin D1 by regulating Arf6 and R-Ras
Mol Cell Biol
2010
30: 3086-3098
|
| 24950743 |
Lee M et al.:
ADAMTS13 and its variants promote angiogenesis via upregulation of VEGF and VEGFR2
Cell Mol Life Sci
2015
72: 349-356
|
| 19916923 |
Aisina RB et al.:
Inhibitory effect of angiostatins on activity of the plasminogen/plasminogen activator system
Biochemistry (Mosc)
2009
74: 1104-1113
|
| 24935208 |
Dobo J et al.:
Multiple roles of complement MASP-1 at the interface of innate immune response and coagulation
Mol Immunol
2014
61: 69-78
|
| 22792348 |
Deleuze V et al.:
Angiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cells
PLoS One
2012
7
|
| 23434824 |
Tsai JJ et al. et al.:
Nrf2 regulates haematopoietic stem cell function
Nat Cell Biol
2013
15: 309-316
|
| 21527521 |
Konopatskaya O et al.:
Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2
Blood
2011
118: 416-424
|
| 31420334 |
Lindstrom S et al. et al.:
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism
Blood
2019
134: 1645-1657
|
| 21441933 |
Schajnovitz A et al. et al.:
CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions
Nat Immunol
2011
12: 391-398
|
| 16293602 |
Kamminga LM et al.:
The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion
Blood
2006
107: 2170-2179
|
| 8343951 |
author information missing
article information missing
|
| 8144663 |
Feldman GM et al.:
Cytokines that associate with the signal transducer gp130 activate the interferon-induced transcription factor p91 by tyrosine phosphorylation.
J. Biol. Chem.
1994
269
|
| 20482616 |
de Groot M et al.:
Reduction of different inflammatory cell types of the innate immune system in psoriatic skin during etanercept treatment
Exp. Dermatol.
2010
19: 754-756
|
| 15860458 |
Liu J et al.:
Interferon regulatory factor 1 is an essential and direct transcriptional activator for interferon {gamma}-induced RANTES/CCl5 expression in macrophages.
J. Biol. Chem.
2005
280
|
| 16125763 |
Seth RB et al.:
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
Cell
2005
122: 669-682
|
| 21896491 |
Antonaki A et al.:
Genomic Analysis Reveals a Novel Nuclear Factor-kappaB (NF-kappaB)-binding Site in Alu-repetitive Elements.
J. Biol. Chem.
2011
286
|
| 7590867 |
Patry C et al.:
Fc alpha receptors mediate release of tumour necrosis factor-alpha and interleukin-6 by human monocytes following receptor aggregation.
Immunology
1995
86: 1-5
|
| 22503541 |
Uderhardt S et al.:
12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance
Immunity
2012
36: 834-846
|
| 12496252 |
Jiang Z et al.:
Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex
J. Biol. Chem.
2003
278
|
| 22726116 |
Gasparini C et al.:
NF-kappaB as a target for modulating inflammatory responses
Curr. Pharm. Des.
2012
18: 5735-5745
|
| 21460227 |
Toubiana J et al.:
IMPDHII protein inhibits Toll-like receptor 2-mediated activation of NF-kappaB
J. Biol. Chem.
2011
286
|
| 18432192 |
Rius J et al.:
NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha
Nature
2008
453: 807-811
|
| 18924132 |
Schmitz F et al.:
Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells
Eur. J. Immunol.
2008
38: 2981-2992
|
| 20458337 |
Buschow SI et al.:
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis
Immunol. Cell Biol.
2010
88: 851-856
|
| 9952022 |
Czerwony G et al.:
Differential surface expression of HLA-DRB1 and HLA-DRB4 among peripheral blood cells of DR4 positive individuals
Hum. Immunol.
1999
60: 1-9
|
| 24075919 |
Yucesoy B et al.:
Genetic variants within the MHC region are associated with immune responsiveness to childhood vaccinations
Vaccine
2013
31: 5381-5391
|
| 23606632 |
Kerscher B et al.:
The Dectin-2 family of C-type lectin-like receptors: an update
Int. Immunol.
2013
25: 271-277
|
| 23678941 |
Fukuda M et al.:
Rab27 effectors, pleiotropic regulators in secretory pathways
Traffic
2013
14: 949-963
|
| 16554019 |
Fukuda M et al.:
Distinct Rab27A binding affinities of Slp2-a and Slac2-a/melanophilin: Hierarchy of Rab27A effectors
Biochem. Biophys. Res. Commun.
2006
343: 666-674
|
| 22308290 |
author information missing
article information missing
|
| 25869671 |
Na BR et al.:
TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse
J. Cell Biol.
2015
209: 143-162
|
| 24204270 |
Ma Z et al.:
DDX24 negatively regulates cytosolic RNA-mediated innate immune signaling
PLoS Pathog.
2013
9
|
| 26427885 |
Gao J et al.:
Miro1-mediated mitochondrial dysfunction under high nutrient stress is linked to NOD-like receptor 3 (NLRP3)-dependent inflammatory responses in rat pancreatic beta cells
Free Radic. Biol. Med.
2015
89: 322-332
|
| 26152662 |
Lee M et al.:
IL-7 receptor deletion ameliorates diet-induced obesity and insulin resistance in mice
Diabetologia
2015
58: 2361-2370
|
| 20064371 |
Brass AL et al.:
The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus
Cell
2009
139: 1243-1254
|
| 18159223 |
Joung I et al.:
Functional Implications in Apoptosis by Interferon Inducible Gene Product 1-8D, the Binding Protein to Adenovirus Preterminal Protein
J. Microbiol.
2003
41: 295-299
|
| 20059963 |
Nara H et al.:
Regulation of interleukin-21 receptor expression and its signal transduction by WSB-2
Biochem. Biophys. Res. Commun.
2010
392: 171-177
|
| 23979957 |
Frederiksen BN et al.:
Association between vitamin D metabolism gene polymorphisms and risk of islet autoimmunity and progression to type 1 diabetes: the diabetes autoimmunity study in the young (DAISY)
J. Clin. Endocrinol. Metab.
2013
98
|
| 27183626 |
Liu TT et al.:
LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner
J. Immunol.
2016
196: 5101-5111
|
| 22966085 |
Degn SE et al.:
Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function
J Immunol
2012
189: 3957-3969
|
| 10781083 |
Geiman TM et al.:
Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes
Proc. Natl. Acad. Sci. U.S.A.
2000
97: 4772-4777
|
| 27506198 |
Halliwill KD et al.:
Panx3 links body mass index and tumorigenesis in a genetically heterogeneous mouse model of carcinogen-induced cancer
Genome Med
2016
8: 83
|
| 22488362 |
Heib V et al.:
Cytip regulates dendritic-cell function in contact hypersensitivity
Eur. J. Immunol.
2012
42: 589-597
|
| 14570581 |
Krause M et al.:
Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration
Annu. Rev. Cell Dev. Biol.
2003
19: 541-564
|
| 11585831 |
Le Roy F et al.:
The 2-5A/RNase L/RNase L inhibitor (RLI) [correction of (RNI)] pathway regulates mitochondrial mRNAs stability in interferon alpha-treated H9 cells
J. Biol. Chem.
2001
276
|
| 21829753 |
Moon JM et al.:
Gene expression profiling of mouse aborted uterus induced by lipopolysac charide
Anat Cell Biol
2011
44: 98-105
|
| 31827077 |
Yang W et al.:
G3BP1 inhibits RNA virus replication by positively regulating RIG-I-mediated cellular antiviral response
Cell Death Dis
2019
10: 946
|
| 31189711 |
Wang J et al.:
Porcine Reproductive and Respiratory Syndrome Virus Activates Lipophagy To Facilitate Viral Replication through Downregulation of NDRG1 Expression
|
| 29730307 |
Chen L et al.:
N-myc downstream-regulated gene 1 facilitates influenza A virus replication by suppressing canonical NF-kappaB signaling
Virus Res.
2018
252: 22-28
|
| 12618906 |
Wiszniewski W et al.:
Novel mutations in the RFXANK gene: RFX complex containing in-vitro-generated RFXANK mutant binds the promoter without transactivating MHC II
Immunogenetics
2003
54: 747-755
|
| 29118118 |
Schweitzer CJ et al.:
N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly
|
| 23661644 |
Kim SV et al.:
GPR15-mediated homing controls immune homeostasis in the large intestine mucosa
Science
2013
340: 1456-1459
|
| 27189710 |
Schumann S et al.:
Interactions between KSHV ORF57 and the novel human TREX proteins, CHTOP and CIP29
J. Gen. Virol.
2016
97: 1904-1910
|
| 11600535 |
Cetani F et al.:
A novel mutation of the autoimmune regulator gene in an Italian kindred with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, acting in a dominant fashion and strongly cosegregating with hypothyroid autoimmune thyroiditis
J. Clin. Endocrinol. Metab.
2001
86: 4747-4752
|
| 15696198 |
Cavadini P et al.:
AIRE deficiency in thymus of 2 patients with Omenn syndrome
J. Clin. Invest.
2005
115: 728-732
|
| 23487421 |
Zeng XL et al.:
Divergent effects of T cell costimulation and inflammatory cytokine production on autoimmune peripheral neuropathy provoked by Aire deficiency
J. Immunol.
2013
190: 3895-3904
|
| 24227843 |
Heurich A et al.:
TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein
J. Virol.
2014
88: 1293-1307
|
| 31147461 |
Sharp TH et al.:
Insights into IgM-mediated complement activation based on in situ structures of IgM-C1-C4b
Proc. Natl. Acad. Sci. U.S.A.
2019
116
|
| 31387635 |
Pereira KMC et al.:
Impact of C4, C4A and C4B gene copy number variation in the susceptibility, phenotype and progression of systemic lupus erythematosus
Adv Rheumatol
2019
59: 36
|
| 31263063 |
Dufek S et al. et al.:
Genetic Identification of Two Novel Loci Associated with Steroid-Sensitive Nephrotic Syndrome
J. Am. Soc. Nephrol.
2019
30: 1375-1384
|
| 32641482 |
Zhao X et al.:
LY6E Restricts the Entry of Human Coronaviruses, Including the Currently Pandemic SARS-CoV-2
|
| 32704094 |
Pfaender S et al. et al.:
LY6E impairs coronavirus fusion and confers immune control of viral disease
|
| 16914735 |
Shi CS et al.:
The mitogen-activated protein kinase kinase kinase kinase GCKR positively regulates canonical and noncanonical Wnt signaling in B lymphocytes
Mol. Cell. Biol.
2006
26: 6511-6521
|
| 26791862 |
Chuang HC et al.:
MAP4K Family Kinases in Immunity and Inflammation
Adv. Immunol.
2016
129: 277-314
|
| 32610122 |
Zheng Z et al. et al.:
Control of Early B Cell Development by the RNA N(6)-Methyladenosine Methylation
Cell Rep
2020
31
|
| 24919548 |
Hermann-Kleiter N et al.:
Orphan nuclear receptor NR2F6 acts as an essential gatekeeper of Th17 CD4+ T cell effector functions
Cell Commun. Signal
2014
12: 38
|
| 19130477 |
Meng X et al.:
PPP1R9B (Neurabin 2): involvement and dynamics in the NK immunological synapse
Eur. J. Immunol.
2009
39: 552-560
|
| 20039296 |
Brckalo T et al.:
Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells
Eur. J. Immunol.
2010
40: 722-732
|
| 7523512 |
Lazarovits AI et al.:
CD7 is associated with CD3 and CD45 on human T cells
J. Immunol.
1994
153: 3956-3966
|
| 8841453 |
Singer MS et al.:
Purification and quantification of L-selectin-reactive GlyCAM-1 from mouse serum
J. Immunol. Methods
1996
196: 153-161
|
| 24097067 |
Lessard CJ et al. et al.:
Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogrens syndrome
Nat. Genet.
2013
45: 1284-1292
|
| 27645564 |
Solano-Collado V et al.:
Rab32 restriction of intracellular bacterial pathogens
Small GTPases
2018
9: 216-223
|
| 21943286 |
Kedmi M et al.:
Decreased expression of B cell related genes in leukocytes of women with Parkinsons disease
Mol Neurodegener
2011
6: 66
|
| 26649771 |
Kim JH et al.:
Expression of Beta-Defensin 131 Promotes an Innate Immune Response in Human Prostate Epithelial Cells
PLoS One
2015
10
|
| 28181499 |
Terkawi MA et al.:
Involvement of beta-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum
Sci Rep
2017
7: 41772
|
| 28616206 |
Tziastoudi M et al.:
A systematic review and meta-analysis of genetic association studies for the role of inflammation and the immune system in diabetic nephropathy
Clin Kidney J
2017
10: 293-300
|
| 26568190 |
Wada J et al.:
Innate immunity in diabetes and diabetic nephropathy
Nat Rev Nephrol
2016
12: 13-26
|
| 16177118 |
Waggoner SN et al.:
gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway
J Immunol
2005
175: 4706-4714
|
| 31369185 |
Yaghubi E et al.:
Effects of l-carnitine supplementation on cardiovascular and bone turnover markers in patients with pemphigus vulgaris under corticosteroids treatment: A randomized, double-blind, controlled trial
Dermatol Ther
2019
32
|
| 18508534 |
Zavasnik-Bergant T et al.:
Cystatin protease inhibitors and immune functions
Front Biosci
2008
13: 4625-4637
|
| 15829557 |
Zavasnik-Bergant T et al.:
Differentiation- and maturation-dependent content, localization, and secretion of cystatin C in human dendritic cells
J Leukoc Biol
2005
78: 122-134
|
| 16978536 |
Zhou T et al.:
DC-SIGN and immunoregulation
Cell Mol Immunol
2006
3: 279-283
|
| 22201836 |
Cai M et al.:
DC-SIGN modulates DC maturation and function in rat renal tubulointerstitial lesions
Front Biosci (Landmark Ed)
2012
17: 1795-1803
|
| 22810896 |
Yamashita M et al.:
Epidermal growth factor receptor is essential for Toll-like receptor 3 signaling
Sci Signal
2012
5: ra50
|
| 26876170 |
Spadaro O et al.:
Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence
Cell Rep
2016
14: 1571-1580
|
| 30657605 |
Ohradanova-Repic A et al.:
The mannose 6-phosphate/insulin-like growth factor 2 receptor mediates plasminogen-induced efferocytosis
J Leukoc Biol
2019
105: 519-530
|
| 29619880 |
Li Y et al.:
Low-dose IL-2 expands CD4(+) regulatory T cells with a suppressive function in vitro via the STAT5-dependent pathway in patients with chronic kidney diseases
Ren Fail
2018
40: 280-288
|
| 22802125 |
HoWangYin KY et al.:
Multimeric structures of HLA-G isoforms function through differential binding to LILRB receptors
Cell Mol Life Sci
2012
69: 4041-4049
|
| 10190900 |
Rajagopalan S et al.:
A human histocompatibility leukocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells
J Exp Med
1999
189: 1093-1100
|
| 32161193 |
Morigi M et al.:
C3a receptor blockade protects podocytes from injury in diabetic nephropathy
|
| 32796023 |
Yang CY et al.:
DUSP11 Attenuates Lipopolysaccharide-Induced Macrophage Activation by Targeting TAK1
J Immunol
2020
205: 1644-1652
|
| 29230705 |
Sheng X et al.:
Crosstalk between TLR4 and Notch1 signaling in the IgA nephropathy during inflammatory response
Int Urol Nephrol
2018
50: 779-785
|
| 25917102 |
Reis BS et al.:
Leptin receptor signaling in T cells is required for Th17 differentiation
J Immunol
2015
194: 5253-5260
|
| 25767073 |
Murshid A et al.:
Emerging roles for scavenger receptor SREC-I in immunity
Cytokine
2015
75: 256-260
|
| 31636192 |
Reverendo M et al.:
Polymerase III transcription is necessary for T cell priming by dendritic cells
Proc Natl Acad Sci U S A
2019
116
|
| 28738171 |
Brady OA et al.:
Emerging roles for TFEB in the immune response and inflammation
Autophagy
2018
14: 181-189
|
| 23664135 |
Ajibade AA et al.:
Cell type-specific function of TAK1 in innate immune signaling
Trends Immunol
2013
34: 307-316
|
| 29735977 |
Du X et al.:
Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice
Cell Mol Immunol
2019
16: 878-886
|
| 25309543 |
Kawasaki T et al.:
Toll-like receptor signaling pathways
Front Immunol
2014
5: 461
|
| 10961870 |
Yokota T et al.:
Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages
Blood
2000
96: 1723-1732
|
| 11489965 |
Rajagopalan S et al.:
Cutting edge: induction of IFN-gamma production but not cytotoxicity by the killer cell Ig-like receptor KIR2DL4 (CD158d) in resting NK cells
J Immunol
2001
167: 1877-1881
|
| 14500636 |
Kikuchi-Maki A et al.:
KIR2DL4 is an IL-2-regulated NK cell receptor that exhibits limited expression in humans but triggers strong IFN-gamma production
J Immunol
2003
171: 3415-3425
|
| 22934097 |
Rajagopalan S et al.:
KIR2DL4 (CD158d): An activation receptor for HLA-G
Front Immunol
2012
3: 258
|
| 3110074 |
author information missing
Cell-mediated immunity and biological response modifiers in insulin-dependent diabetes mellitus complicated by end-stage renal disease
Int Arch Allergy Appl Immunol
1987
83: 278-283
|
| 15827959 |
Jordan WJ et al.:
Human IL-19 regulates immunity through auto-induction of IL-19 and production of IL-10
Eur J Immunol
2005
35: 1576-1582
|
| 28726774 |
Wang S et al. et al.:
Interleukin-22 ameliorated renal injury and fibrosis in diabetic nephropathy through inhibition of NLRP3 inflammasome activation
Cell Death Dis
2017
8: e2937
|
| 19859064 |
Medzhitov R et al.:
Transcriptional control of the inflammatory response
Nat Rev Immunol
2009
9: 692-703
|
| 26095358 |
Heinz LX et al. et al.:
The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity
Cell Rep
2015
11: 1919-1928
|
| 22233340 |
Navarro MN et al.:
Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells
Biochem J
2012
442: 649-659
|
| 20819079 |
Matthews SA et al.:
Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells
Biochem J
2010
432: 153-163
|
| 16455998 |
Pozo D et al.:
CD161 (human NKR-P1A) signaling in NK cells involves the activation of acid sphingomyelinase
J Immunol
2006
176: 2397-2406
|
| 31145102 |
Halkias J et al.:
CD161 contributes to prenatal immune suppression of IFNgamma-producing PLZF+ T cells
J Clin Invest
2019
129: 3562-3577
|
| 29686665 |
Kurioka A et al. et al.:
CD161 Defines a Functionally Distinct Subset of Pro-Inflammatory Natural Killer Cells
Front Immunol
2018
9: 486
|
| 16339513 |
Rosen DB et al.:
Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor
J Immunol
2005
175: 7796-7799
|
| 19041431 |
Linkermann A et al.:
Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes
Biochim Biophys Acta
2009
1794: 168-176
|
| 32578129 |
Abolnezhadian F et al.:
A novel mutation in RFXANK gene and low B cell count in a patient with MHC class II deficiency: a case report
Immunol Res
2020
68: 225-231
|
| 29362422 |
Forsberg J et al.:
A caspase-2-RFXANK interaction and its implication for MHC class II expression
Cell Death Dis
2018
9: 80
|
| 31767682 |
Yasukawa K et al.:
The microRNAs miR-302b and miR-372 regulate mitochondrial metabolism via the SLC25A12 transporter, which controls MAVS-mediated antiviral innate immunity
J Biol Chem
2020
295: 444-457
|
| 15626471 |
Allam A et al.:
Role of the adaptor proteins Bam32, TAPP1 and TAPP2 in lymphocyte activation
Immunol Lett
2005
97: 7-17
|
| 11773082 |
Kuroda TS et al.:
The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain
J Biol Chem
2002
277: 9212-9218
|
| 21915328 |
Eidson M et al.:
Altered development of NKT cells, gammadelta T cells, CD8 T cells and NK cells in a PLZF deficient patient
PLoS One
2011
6
|
| 22342841 |
author information missing
article information missing
|
| 21757742 |
author information missing
article information missing
|
| 30867837 |
author information missing
article information missing
|
| 32298652 |
author information missing
article information missing
|
| 20190752 |
author information missing
article information missing
|
| 22561518 |
author information missing
article information missing
|
| 27052415 |
author information missing
article information missing
|
| 31552021 |
author information missing
article information missing
|
| 24127487 |
author information missing
article information missing
|
| 17228323 |
author information missing
article information missing
|
| 29371118 |
author information missing
article information missing
|
| 39739423 |
author information missing
article information missing
|
| 18250427 |
author information missing
article information missing
|
| 32436623 |
author information missing
article information missing
|
| 18456456 |
author information missing
article information missing
|
| 12827612 |
author information missing
article information missing
|
| 24480247 |
author information missing
article information missing
|
| 16026592 |
author information missing
article information missing
|
| 16845400 |
author information missing
article information missing
|
| 18341631 |
author information missing
article information missing
|
| 37759792 |
author information missing
article information missing
|
| 37954647 |
author information missing
article information missing
|
| 38137358 |
author information missing
article information missing
|
| 2351942 |
author information missing
article information missing
|
| 36642058 |
author information missing
article information missing
|
| 16352719 |
Smith WW et al.:
Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.
Proc. Natl. Acad. Sci. U.S.A.
2005
102
|
| 17922679 |
Kim HY et al.:
Methionine sulfoxide reductases: selenoprotein forms and roles in antioxidant protein repair in mammals
Biochem. J.
2007
407: 321-329
|
| 23800641 |
Zimmerman HA et al.:
Adipose transplant for inborn errors of branched chain amino acid metabolism in mice
Mol. Genet. Metab.
2013
4: 345-353
|
| 23086801 |
Oyarzabal A et al.:
A novel regulatory defect in the branched-chain alpha-keto acid dehydrogenase complex due to a mutation in the PPM1K gene causes a mild variant phenotype of maple syrup urine disease
Hum. Mutat.
2013
34: 355-362
|
| 20300014 |
Sharp CP et al.:
Amino acid supplements and recovery from high-intensity resistance training
J Strength Cond Res
2010
24: 1125-1130
|
| 11168296 |
Hammarqvist F et al.:
Stress hormones initiate prolonged changes in the muscle amino acid pattern
Clin Physiol
2001
21: 44-50
|
| 18513745 |
Zhou A et al.:
The S-to-R transition of corticosteroid-binding globulin and the mechanism of hormone release
J. Mol. Biol.
2008
380: 244-251
|
| 386083 |
et al.:
Glucocorticoid hormone action: an overview
Monogr Endocrinol
1979
12: 1-24
|
| 18536531 |
Oberlander TF et al.:
Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
Epigenetics
2008
3: 97-106
|
| 15220929 |
Weaver IC et al.:
Epigenetic programming by maternal behavior
Nat. Neurosci.
2004
7: 847-854
|
| 15464020 |
Hayashi R et al.:
Effects of glucocorticoids on gene transcription
Eur. J. Pharmacol.
2004
500: 51-62
|
| 21798242 |
Zhou F et al.:
Wnt/beta-catenin signal pathway stabilizes APP intracellular domain (AICD) and promotes its transcriptional activity
Biochem. Biophys. Res. Commun.
2011
412: 68-73
|
| 19416884 |
Zhou J et al.:
mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 7840-7845
|
| 21741044 |
Leiva A et al.:
Mechanisms regulating hepatic SR-BI expression and their impact on HDL metabolism
Atherosclerosis
2011
217: 299-307
|
| 17318191 |
Coluccia AM et al.:
Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation
EMBO J.
2007
26: 1456-1466
|
| 22872237 |
Subauste AR et al.:
Alterations in lipid signaling underlie lipodystrophy secondary to AGPAT2 mutations
Diabetes
2012
61: 2922-2931
|
| 22872237 |
Subauste AR et al.:
Alterations in lipid signaling underlie lipodystrophy secondary to AGPAT2 mutations
Diabetes
2012
11: 2922-2931
|
| 21602191 |
Prochazkova J et al.:
The interplay of the aryl hydrocarbon receptor and beta-catenin alters both AhR-dependent transcription and Wnt/beta-catenin signaling in liver progenitors
Toxicol. Sci.
2011
122: 349-360
|
| 19043829 |
Chandra V et al.:
Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA
Nature
2008
7220: 350-356
|
| 11851396 |
Lee WY et al.:
Interactions of RXR with coactivators are differentially mediated by helix 11 of the receptors ligand binding domain
Biochemistry
2002
41: 2500-2508
|
| 23319938 |
Osz J et al.:
Solution Structures of PPARgamma2/RXRalpha Complexes
PPAR Res
2012
2012
|
| 16423883 |
Jeong JW et al.:
The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism
Mol. Endocrinol.
2006
20: 1138-1152
|
| 10862621 |
Grimaldi PA et al.:
The roles of PPARs in adipocyte differentiation
Prog. Lipid Res.
2001
40: 269-281
|
| 10409739 |
Fajas L et al.:
Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism
Mol. Cell. Biol.
1999
19: 5495-5503
|
| 16495223 |
Gale SE et al.:
A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation
J. Biol. Chem.
2006
281
|
| 10419513 |
Bastie C et al.:
Expression of peroxisome proliferator-activated receptor PPARdelta promotes induction of PPARgamma and adipocyte differentiation in 3T3C2 fibroblasts
J. Biol. Chem.
1999
274
|
| 16895991 |
Parakh TN et al.:
Follicle-stimulating hormone/cAMP regulation of aromatase gene expression requires beta-catenin
Proc. Natl. Acad. Sci. U.S.A.
2006
103
|
| 21967974 |
Avagyan S et al.:
Quantitative trait mapping reveals a regulatory axis involving peroxisome proliferator-activated receptors, PRDM16, transforming growth factor-beta2 and FLT3 in hematopoiesis
Blood
2011
118: 6078-6086
|
| 22179528 |
Grimm MO et al.:
The role of APP proteolytic processing in lipid metabolism
Exp Brain Res
2012
217: 365-375
|
| 15073272 |
Lengqvist J et al.:
Polyunsaturated fatty acids including docosahexaenoic and arachidonic acid bind to the retinoid X receptor alpha ligand-binding domain
Mol. Cell Proteomics
2004
7: 692-703
|
| 16039987 |
Francke F et al.:
MYND domain specific interaction of the melanin-concentrating hormone receptor 1 interacting zinc-finger protein with alpha- and beta-tubulin
Biochem. Biophys. Res. Commun.
2005
334: 1292-1298
|
| 12208518 |
Bachner D et al.:
MIZIP, a highly conserved, vertebrate specific melanin-concentrating hormone receptor 1 interacting zinc-finger protein
FEBS Lett.
2002
526: 124-128
|
| 10471841 |
Bachner D et al.:
Identification of melanin concentrating hormone (MCH) as the natural ligand for the orphan somatostatin-like receptor 1 (SLC-1)
FEBS Lett.
1999
457: 522-524
|
| 11154732 |
Vasiliou V et al.:
Role of aldehyde dehydrogenases in endogenous and xenobiotic metabolism
Chem. Biol. Interact.
2000
129: 1-19
|
| 21988832 |
Wang J et al.:
Toward an understanding of the protein interaction network of the human liver
Mol. Syst. Biol.
2011
7: 536
|
| 23703578 |
Chauvin B et al.:
Drug-Drug Interactions Between HMG-CoA Reductase Inhibitors (Statins) and Antiviral Protease Inhibitors
Clin Pharmacokinet
2013
52: 815-831
|
| 22131415 |
Ma T et al.:
Synaptic stimulation of mTOR is mediated by Wnt signaling and regulation of glycogen synthetase kinase-3
J. Neurosci.
2011
31
|
| 12524443 |
Borge PD Jr et al.:
Insulin receptor substrate 1 regulation of sarco-endoplasmic reticulum calcium ATPase 3 in insulin-secreting beta-cells
J. Biol. Chem.
2003
278
|
| 12736081 |
Srivastava RA et al.:
Scavenger receptor class B type I expression in murine brain and regulation by estrogen and dietary cholesterol
J. Neurol. Sci.
2003
210: 11-18
|
| 24148205 |
Husemann J et al.:
Expression of scavenger receptor class B, type I, by astrocytes and vascular smooth muscle cells in normal adult mouse and human brain and in Alzheimers disease brain
Am. J. Pathol.
2001
158: 825-832
|
| 9600988 |
Simons M et al.:
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons
Proc. Natl. Acad. Sci. U.S.A.
1998
95: 6460-6464
|
| 21257714 |
Marquer C et al.:
Local cholesterol increase triggers amyloid precursor protein-Bace1 clustering in lipid rafts and rapid endocytosis
FASEB J.
2011
4: 1295-1305
|
| 11296263 |
Fassbender K et al.:
Simvastatin strongly reduces levels of Alzheimers disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo
Proc. Natl. Acad. Sci. U.S.A.
2001
98: 5856-5861
|
| 19094065 |
Liu WW et al.:
A novel reciprocal and biphasic relationship between membrane cholesterol and beta-secretase activity in SH-SY5Y cells and in human platelets
J. Neurochem.
2009
108: 341-349
|
| 16227967 |
Grimm MO et al.:
Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin
Nat. Cell Biol.
2005
11: 1118-1123
|
| 21822420 |
Rivera-Zavala JB et al.:
Changes in the 24 h Rhythmicity of Liver PPARs and Peroxisomal Markers When Feeding Is Restricted to Two Daytime Hours
PPAR Res
2011
2011
|
| 22865928 |
Vikstrom Bergander L et al.:
Tryptamine serves as a proligand of the AhR transcriptional pathway whose activation is dependent of monoamine oxidases
Mol. Endocrinol.
2012
26: 1542-1551
|
| 11063613 |
Rooke N et al.:
The mitochondrial monoamine oxidase-aldehyde dehydrogenase pathway: a potential site of action of daidzin
J. Med. Chem.
2000
43: 4169-4179
|
| 18308724 |
Grimm MO et al.:
Independent inhibition of Alzheimer disease beta- and gamma-secretase cleavage by lowered cholesterol levels
J. Biol. Chem.
2008
283
|
| 22177902 |
Beyer T et al.:
Serotonin signaling is required for Wnt-dependent GRP specification and leftward flow in Xenopus
Curr. Biol.
2012
22: 33-39
|
| 16882880 |
Martinez-Jimenez CP et al.:
Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1
Mol. Pharmacol.
2006
70: 1681-1692
|
| 19962449 |
Hao Q et al.:
ADD1/SREBP1c activates the PGC1-alpha promoter in brown adipocytes
Biochim. Biophys. Acta
2010
1801: 421-429
|
| 1536570 |
Spink DC et al.:
17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1A1: a comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA
Arch. Biochem. Biophys.
1992
293: 342-348
|
| 9261096 |
Ji Y et al.:
Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux
J. Biol. Chem.
1997
272
|
| 12168771 |
Napolitano M et al.:
17beta-estradiol enhances the flux of cholesterol through the cholesteryl ester cycle in human macrophages
Biosci. Rep.
2001
21: 637-652
|
| 17359297 |
Mermelstein CS et al.:
Wnt/beta-catenin pathway activation and myogenic differentiation are induced by cholesterol depletion
Differentiation
2007
75: 184-192
|
| 19307298 |
Hamann M et al.:
Human ClCa1 modulates anionic conduction of calcium-dependent chloride currents
J. Physiol. (Lond.)
2009
587: 2255-2274
|
| 10362588 |
Gruber AD et al.:
Molecular cloning and transmembrane structure of hCLCA2 from human lung, trachea, and mammary gland
Am. J. Physiol.
1999
276
|
| 14512419 |
Abdel-Ghany M et al.:
The interacting binding domains of the beta(4) integrin and calcium-activated chloride channels (CLCAs) in metastasis
J. Biol. Chem.
2003
278
|
| 16273093 |
Jones RB et al.:
A quantitative protein interaction network for the ErbB receptors using protein microarrays
Nature
2006
439: 168-174
|
| 23043943 |
Grzesiak M et al.:
Elevated level of 17beta-estradiol is associated with overexpression of FSHR, CYP19A1, and CTNNB1 genes in porcine ovarian follicles after prenatal and neonatal flutamide exposure
Theriogenology
2012
78: 2050-2060
|
| 10893236 |
Das SK et al.:
Estrogen targets genes involved in protein processing, calcium homeostasis, and Wnt signaling in the mouse uterus independent of estrogen receptor-alpha and -beta
J. Biol. Chem.
2000
275
|
| 22862945 |
Westerterp M et al.:
Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways
Cell Stem Cell
2012
11: 195-206
|
| 2347305 |
Grupe A et al.:
Cloning and expression of a human voltage-gated potassium channel. A novel member of the RCK potassium channel family
EMBO J.
1990
9: 1749-1756
|
| 19619488 |
MacDonald BT et al.:
Wnt/beta-catenin signaling: components, mechanisms, and diseases
Dev. Cell
2009
17: 9-26
|
| 9247128 |
Alroy I et al.:
The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions
FEBS Lett.
1997
410: 83-86
|
| 21494248 |
Adrain C et al.:
Mammalian EGF receptor activation by the rhomboid protease RHBDL2
EMBO Rep.
2011
12: 421-427
|
| 18308724 |
Grimm MO et al.:
Independent inhibition of Alzheimer disease beta- and gamma-secretase cleavage by lowered cholesterol levels
J. Biol. Chem.
2008
283
|
| 18702528 |
Beel AJ et al.:
Structural studies of the transmembrane C-terminal domain of the amyloid precursor protein (APP): does APP function as a cholesterol sensor? }, authors { names std { { name ml Beel AJ, affil str Department of Biochemistry and Center for Structural Biology, Vanderbilt University, Nashville, Tennessee 37232-8725, USA
Biochemistry
2008
47: 9428-9446
|
| 20304095 |
Beel AJ et al.:
Direct binding of cholesterol to the amyloid precursor protein: An important interaction in lipid-Alzheimers disease relationships? }, authors { names std { { name ml Beel AJ, affil str Department of Biochemistry and Center for Structural Biology, Vanderbilt University School of Medicine, Nashville, TN 37232-8725, USA
Biochim. Biophys. Acta
2010
1801: 975-982
|
| 24249638 |
Wang W et al.:
Amyloid precursor protein alpha- and beta-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2
FASEB J.
2014
28: 849-860
|
| 24249638 |
Wang W et al.:
Amyloid precursor protein alpha- and beta-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2
FASEB J.
2014
2: 849-860
|
| 11240025 |
Husemann J et al.:
Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid
J. Neuroimmunol.
2001
114: 142-150
|
| 8751442 |
El Khoury J et al.:
Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils
Nature
1996
6593: 716-719
|
| 15486308 |
Treguier M et al.:
Transcription factor sterol regulatory element binding protein 2 regulates scavenger receptor Cla-1 gene expression
Arterioscler. Thromb. Vasc. Biol.
2004
24: 2358-2364
|
| 23554170 |
Pierrot N et al.:
Amyloid precursor protein controls cholesterol turnover needed for neuronal activity
EMBO Mol Med
2013
4: 608-625
|
| 23554170 |
Pierrot N et al.:
Amyloid precursor protein controls cholesterol turnover needed for neuronal activity
EMBO Mol Med
2013
5: 608-625
|
| 12206998 |
Yao ZX et al.:
Function of beta-amyloid in cholesterol transport: a lead to neurotoxicity
FASEB J.
2002
12: 1677-1679
|
| 3283935 |
Mahley RW et al.:
Apolipoprotein E: cholesterol transport protein with expanding role in cell biology
Science
1988
240: 622-630
|
| 8089103 |
LaDu MJ et al.:
Isoform-specific binding of apolipoprotein E to beta-amyloid
J. Biol. Chem.
1994
269
|
| 7619525 |
Naslund J et al.:
Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimers disease brain
Neuron
1995
15: 219-228
|
| 9326304 |
Avdulov NA et al.:
Lipid binding to amyloid beta-peptide aggregates: preferential binding of cholesterol as compared with phosphatidylcholine and fatty acids
J. Neurochem.
1997
69: 1746-1752
|
| 23497222 |
Xu T et al.:
Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study
BMC Med
2013
11: 60
|
| 21076037 |
Thanopoulou K et al.:
Scavenger receptor class B type I (SR-BI) regulates perivascular macrophages and modifies amyloid pathology in an Alzheimer mouse model
Proc. Natl. Acad. Sci. U.S.A.
2010
107
|
| 9165109 |
Lindhorst E et al.:
Acute inflammation, acute phase serum amyloid A and cholesterol metabolism in the mouse
Biochim. Biophys. Acta
1997
1339: 143-154
|
| 7685338 |
Marletta MA et al.:
Nitric oxide synthase structure and mechanism
J. Biol. Chem.
1993
268
|
| 10551825 |
Stangl H et al.:
Transport of lipids from high and low density lipoproteins via scavenger receptor-BI
J. Biol. Chem.
1999
274
|
| 12763030 |
Malerod L et al.:
Hepatic scavenger receptor class B, type I is stimulated by peroxisome proliferator-activated receptor gamma and hepatocyte nuclear factor 4alpha
Biochem. Biophys. Res. Commun.
2003
305: 557-565
|
| 22927251 |
Williams AB et al.:
Fluvastatin inhibits FLT3 glycosylation in human and murine cells and prolongs survival of mice with FLT3/ITD leukemia
Blood
2012
120: 3069-3079
|
| 20732877 |
Gerin I et al.:
Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation
J. Biol. Chem.
2010
285
|
| 24465716 |
Du S et al.:
Fructose-bisphosphate aldolase a is a potential metastasis-associated marker of lung squamous cell carcinoma and promotes lung cell tumorigenesis and migration
PLoS ONE
2014
9
|
| 24993527 |
Caspi M et al.:
Aldolase positively regulates of the canonical Wnt signaling pathway
Mol Cancer
2014
13: 164
|
| 23663784 |
Leppek K et al.:
Roquin promotes constitutive mRNA decay via a conserved class of stem-loop recognition motifs
Cell
2013
153: 869-881
|
| 11790780 |
Lin S et al.:
A novel S-adenosyl-L-methionine:arsenic(III) methyltransferase from rat liver cytosol
J. Biol. Chem.
2002
277
|
| 9133539 |
Bhattacharyya M et al.:
The role of leucocytes in the acetyl salicylic acid (aspirin) induced nitric oxide synthesis in the production of interferon-alpha, a potent inhibitor of platelet aggregation and a thrombolytic agent
J. Thromb. Thrombolysis
2009
28: 173-184
|
| 24340027 |
Gao Y et al.:
Crosstalk between Wnt/beta-catenin and estrogen receptor signaling synergistically promotes osteogenic differentiation of mesenchymal progenitor cells
PLoS ONE
2013
8
|
| 11923480 |
Leitges M et al.:
Knockout of PKC alpha enhances insulin signaling through PI3K
Mol. Endocrinol.
2002
16: 847-858
|
| 19395872 |
Thoreen CC et al.:
Rapamycin inhibits mTORC1, but not completely
Autophagy
2009
5: 725-726
|
| 19150980 |
Thoreen CC et al.:
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
J. Biol. Chem.
2009
284: 8023-8032
|
| 24856209 |
Chaves I et al.:
Insulin-FOXO3 signaling modulates circadian rhythms via regulation of clock transcription
Curr. Biol.
2014
24: 1248-1255
|
| 21621563 |
Dobson M et al.:
Bimodal regulation of FoxO3 by AKT and 14-3-3
Biochim. Biophys. Acta
2011
1813: 1453-1464
|
| 23131847 |
Kikani CK et al.:
Proliferative and antiapoptotic signaling stimulated by nuclear-localized PDK1 results in oncogenesis
Sci Signal
2012
5: RA80
|
| 24627477 |
Dadi PK et al.:
Inhibition of pancreatic beta-cell Ca2+/calmodulin-dependent protein kinase II reduces glucose-stimulated calcium influx and insulin secretion, impairing glucose tolerance
J. Biol. Chem.
2014
289
|
| 17617409 |
Wood CD et al.:
Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D
FEBS Lett.
2007
581: 3494-3498
|
| 7651388 |
Chen D et al.:
Insulin receptor substrate 1 rescues insulin action in CHO cells expressing mutant insulin receptors that lack a juxtamembrane NPXY motif
Mol. Cell. Biol.
1995
15: 4711-4717
|
| 9165038 |
Kao AW et al.:
Insulin stimulates the phosphorylation of the 66- and 52-kilodalton Shc isoforms by distinct pathways
Endocrinology
1997
138: 2474-2480
|
| 9658397 |
Rocchi S et al.:
Determination of Gab1 (Grb2-associated binder-1) interaction with insulin receptor-signaling molecules
Mol. Endocrinol.
1998
12: 914-923
|
| 10842168 |
Janez A et al.:
The osmotic shock-induced glucose transport pathway in 3T3-L1 adipocytes is mediated by gab-1 and requires Gab-1-associated phosphatidylinositol 3-kinase activity for full activation
J. Biol. Chem.
2000
275
|
| 11314042 |
Lewitzky M et al.:
The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif
Oncogene
2001
20: 1052-1062
|
| 17315038 |
LeRoith D et al.:
Mechanisms of disease: metabolic effects of growth hormone and insulin-like growth factor 1
Nat Clin Pract Endocrinol Metab
2007
3: 302-310
|
| 7541045 |
Craparo A et al.:
Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor
J. Biol. Chem.
1995
270
|
| 12754525 |
Puigserver P et al.:
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
Nature
2003
423: 550-555
|
| 24692138 |
Rui L et al.:
Energy metabolism in the liver
Compr Physiol
2014
4: 177-197
|
| 19324885 |
Olmos Y et al.:
Mutual dependence of Foxo3a and PGC-1alpha in the induction of oxidative stress genes
J. Biol. Chem.
2009
284
|
| 25245339 |
De Filippo G et al.:
Interleukin-6, soluble interleukin-6 receptor/interleukin-6 complex and insulin resistance in obese children and adolescents
J. Endocrinol. Invest.
2015
38: 339-343
|
| 18426864 |
Feral CC et al.:
Blockade of alpha4 integrin signaling ameliorates the metabolic consequences of high-fat diet-induced obesity
Diabetes
2008
57: 1842-1851
|
| 23161216 |
Li XN et al. et al.:
The role of voltage-gated potassium channels Kv2.1 and Kv2.2 in the regulation of insulin and somatostatin release from pancreatic islets
J Pharmacol Exp Ther
2013
344: 407-416
|
| 14988243 |
Yan L et al.:
Expression of voltage-gated potassium channels in human and rhesus pancreatic islets
Diabetes
2004
53: 597-607
|
| 25263798 |
Anju TR et al.:
Long term effects of neonatal hypoglycaemia on pancreatic function
Arch. Physiol. Biochem.
2015
121: 1-12
|
| 23211512 |
Schwetz TA et al.:
Neuropeptide Y and somatostatin inhibit insulin secretion through different mechanisms
Am. J. Physiol. Endocrinol. Metab.
2013
304: E211-E221
|
| 21134130 |
Lin Y et al.:
Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway
FEBS J.
2011
278: 354-370
|
| 19690069 |
Mori H et al.:
Critical roles for the TSC-mTOR pathway in beta-cell function
Am J Physiol Endocrinol Metab
2009
297
|
| 24036112 |
Smadja-Lamere N et al.:
Insulin activates RSK (p90 ribosomal S6 kinase) to trigger a new negative feedback loop that regulates insulin signaling for glucose metabolism
J. Biol. Chem.
2013
288
|
| 23738904 |
Yang SC et al.:
Circadian-clock system in mouse liver affected by insulin resistance
Chronobiol. Int.
2013
30: 796-810
|
| 15684402 |
Nowak M et al.:
Insulin-mediated down-regulation of apolipoprotein A5 gene expression through the phosphatidylinositol 3-kinase pathway: role of upstream stimulatory factor
Mol. Cell. Biol.
2005
25: 1537-1548
|
| 18562674 |
Nitert MD et al.:
CaV1.2 rather than CaV1.3 is coupled to glucose-stimulated insulin secretion in INS-1 832/13 cells
J. Mol. Endocrinol.
2008
41: 1-11
|
| 23389954 |
Tsai SH et al.:
Knockdown of RyR3 enhances adiponectin expression through an atf3-dependent pathway
Endocrinology
2013
154: 1117-1129
|
| 21576825 |
Bezy O et al.:
PKCdelta regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans
J. Clin. Invest.
2011
121: 2504-2517
|
| 17452444 |
Jones N et al.:
Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase
Mol. Cell. Biol.
2007
27: 4759-4773
|
| 10744689 |
Rondinone CM et al.:
Phosphorylation of PDE3B by phosphatidylinositol 3-kinase associated with the insulin receptor
J. Biol. Chem.
2000
275
|
| 8070584 |
Rahn T et al.:
Essential role of phosphatidylinositol 3-kinase in insulin-induced activation and phosphorylation of the cGMP-inhibited cAMP phosphodiesterase in rat adipocytes. Studies using the selective inhibitor wortmannin
FEBS Lett.
1994
350: 314-318
|
| 21864752 |
Dimitriadis G et al.:
Insulin effects in muscle and adipose tissue
Diabetes Res. Clin. Pract.
2011
93: S52-S59
|
| 22848656 |
Nagel JM et al.:
Reduced intestinal tumorigenesis in APCmin mice lacking melanin-concentrating hormone
PLoS ONE
2012
7
|
| 22613765 |
Zhou F et al.:
The APP intracellular domain (AICD) inhibits Wnt signalling and promotes neurite outgrowth
Biochim. Biophys. Acta
2012
1823: 1233-1241
|
| 10421367 |
Chambers J et al.:
Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1
Nature
1999
400: 261-265
|
| 22964922 |
Fox MA et al.:
Mutations in monoamine oxidase (MAO) genes in mice lead to hypersensitivity to serotonin-enhancing drugs: implications for drug side effects in humans
Pharmacogenomics J.
2013
13: 551-557
|
| 17052453 |
Zhang HH et al.:
S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt
Mol. Cell
2006
24: 185-197
|
| 17555873 |
Raju J et al.:
Diosgenin, a naturally occurring steroid [corrected] saponin suppresses 3-hydroxy-3-methylglutaryl CoA reductase expression and induces apoptosis in HCT-116 human colon carcinoma cells
Cancer Lett.
2007
255: 194-204
|
| 24616100 |
Geng Y et al.:
Insulin receptor substrate 1/2 (IRS1/2) regulates Wnt/beta-catenin signaling through blocking autophagic degradation of dishevelled2
J. Biol. Chem.
2014
289
|
| 25024088 |
Sheng R et al.:
Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signalling
Nat Commun
2014
5: 4393
|
| 17203201 |
Katoh M et al.:
STAT3-induced WNT5A signaling loop in embryonic stem cells, adult normal tissues, chronic persistent inflammation, rheumatoid arthritis and cancer (Review)
Int. J. Mol. Med.
2007
19: 273-278
|
| 22897592 |
Kashyap MP et al.:
Pkb/Akt1 mediates Wnt/GSK3beta/beta-catenin signaling-induced apoptosis in human cord blood stem cells exposed to organophosphate pesticide monocrotophos
Stem Cells Dev.
2013
22: 224-238
|
| 17121917 |
Roudier E et al.:
Statins induce mammalian target of rapamycin (mTOR)-mediated inhibition of Akt signaling and sensitize p53-deficient cells to cytostatic drugs
Mol. Cancer Ther.
2006
5: 2706-2715
|
| 20639871 |
Gao C et al.:
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation
Nat. Cell Biol.
2010
12: 781-790
|
| 11522780 |
El-Tanani M et al.:
Differential modulation of transcriptional activity of estrogen receptors by direct protein-protein interactions with the T cell factor family of transcription factors
J. Biol. Chem.
2001
276
|
| 19520794 |
Cleveland AG et al.:
Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice
Carcinogenesis
2009
30: 1581-1590
|
| 23017025 |
Kong W et al.:
Characterization of sFRP2-like in amphioxus: insights into the evolutionary conservation of Wnt antagonizing function
Evol. Dev.
2012
14: 168-177
|
| 18983830 |
Uno S et al.:
Suppression of beta-catenin signaling by liver X receptor ligands
Biochem. Pharmacol.
2009
77: 186-195
|
| 22939629 |
Havugimana PC et al.:
A census of human soluble protein complexes
Cell
2012
150: 1068-1081
|
| 23455922 |
Varjosalo M et al.:
Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS
Nat. Methods
2013
10: 307-314
|
| 22729819 |
Opladen T et al.:
An international survey of patients with tetrahydrobiopterin deficiencies presenting with hyperphenylalaninaemia
J. Inherit. Metab. Dis.
2012
35: 963-973
|
| 22522443 |
Friedman J et al.:
Sepiapterin reductase deficiency: a treatable mimic of cerebral palsy
Ann. Neurol.
2012
71: 520-530
|
| 18296609 |
Zhang C et al.:
Inhibition of human dental pulp stem cell differentiation by Notch signaling
J. Dent. Res.
2008
87: 250-255
|
| 18621708 |
Tang W et al.:
A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 9697-9702
|
| 19357274 |
Vue TY et al.:
Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice
J. Neurosci.
2009
29: 4484-4497
|
| 11408933 |
Scandurro AB et al.:
Gene microarray analysis reveals a novel hypoxia signal transduction pathway in human hepatocellular carcinoma cells
Int. J. Oncol.
2001
19: 129-135
|
| 19789182 |
Tifft KE et al.:
Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases
J. Cell. Sci.
2009
122: 3780-3790
|
| 17034757 |
Xiong H et al.:
Molecular interaction between fukutin and POMGnT1 in the glycosylation pathway of alpha-dystroglycan
Biochem. Biophys. Res. Commun.
2006
350: 935-941
|
| 19615732 |
Sowa ME et al.:
Defining the human deubiquitinating enzyme interaction landscape
Cell
2009
138: 389-403
|
| 21423662 |
Hishiya A et al.:
BAG3 directly interacts with mutated alphaB-crystallin to suppress its aggregation and toxicity
PLoS ONE
2011
6
|
| 22105166 |
Weihl CC et al.:
Another VCP interactor: NF is enough
J. Clin. Invest.
2011
121: 4627-4630
|
| 8063857 |
Eilertsen KJ et al.:
Cellular titin localization in stress fibers and interaction with myosin II filaments in vitro
J. Cell Biol.
1994
126: 1201-1210
|
| 22863883 |
Kristensen AR et al.:
A high-throughput approach for measuring temporal changes in the interactome
Nat. Methods
2012
9: 907-909
|
| 22632968 |
Sosa BA et al.:
LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins
Cell
2012
149: 1035-1047
|
| 12163176 |
Mislow JM et al.:
Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitro
FEBS Lett.
2002
525: 135-140
|
| 14749128 |
Tan C et al.:
Regulation of tumor angiogenesis by integrin-linked kinase (ILK)
Cancer Cell
2004
5: 79-90
|
| 12118075 |
Zhen YY et al.:
NUANCE, a giant protein connecting the nucleus and actin cytoskeleton
J. Cell. Sci.
2002
115: 3207-3222
|
| 17620012 |
Holaska JM et al.:
An emerin proteome: purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture
Biochemistry
2007
46: 8897-8908
|
| 17620599 |
Xiao K et al.:
Functional specialization of beta-arrestin interactions revealed by proteomic analysis
Proc. Natl. Acad. Sci. U.S.A.
2007
104
|
| 22899799 |
Hamidi T et al.:
Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death
Clin. Cancer Res.
2012
18: 5234-5246
|
| 18066051 |
McKinnell IW et al.:
Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex
Nat. Cell Biol.
2008
10: 77-84
|
| 20682791 |
Gorbea C et al.:
A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components
J. Biol. Chem.
2010
285
|
| 8341688 |
Nakafuku M et al.:
Suppression of oncogenic Ras by mutant neurofibromatosis type 1 genes with single amino acid substitutions
Proc. Natl. Acad. Sci. U.S.A.
1993
90: 6706-6710
|
| 20080536 |
Lin TW et al.:
Label-free detection of protein-protein interactions using a calmodulin-modified nanowire transistor
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 1047-1052
|
| 15840729 |
Shen X et al.:
Scanning the human proteome for calmodulin-binding proteins
Proc. Natl. Acad. Sci. U.S.A.
2005
102: 5969-5974
|
| 12153558 |
Benaim G et al.:
Phosphorylation of calmodulin. Functional implications
Eur. J. Biochem.
2002
269: 3619-3631
|
| 12672969 |
Alto NM et al.:
Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 4445-4450
|
| 11799244 |
Marx SO et al.:
Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel
Science
2002
295: 496-499
|
| 10945988 |
Takahashi M et al.:
Association of immature hypophosphorylated protein kinase cepsilon with an anchoring protein CG-NAP
J. Biol. Chem.
2000
275
|
| 20936779 |
Bandyopadhyay S et al.:
A human MAP kinase interactome
Nat. Methods
2010
7: 801-805
|
| 19279214 |
Fallon JL et al.:
Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+* calmodulins
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 5135-5140
|
| 21186355 |
Altier C et al.:
The Cavbeta subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels
Nat. Neurosci.
2011
14: 173-180
|
| 1320193 |
Lehmann JM et al.:
RAR gamma 2 expression is regulated through a retinoic acid response element embedded in Sp1 sites
Mol. Cell. Biol.
1992
12: 2976-2985
|
| 16818493 |
Head BP et al.:
Microtubules and actin microfilaments regulate lipid raft/caveolae localization of adenylyl cyclase signaling components
J. Biol. Chem.
2006
281
|
| 10915780 |
D'Amico M et al.:
The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways
J. Biol. Chem.
2000
275
|
| 12824296 |
Ortega-Velazquez R et al.:
Arg-Gly-Asp-Ser (RGDS) peptide stimulates transforming growth factor beta1 transcription and secretion through integrin activation
FASEB J.
2003
17: 1529-1531
|
| 19738201 |
Humphries JD et al.:
Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6
Sci Signal
2009
2: RA51
|
| 23612611 |
Radovanac K et al.:
Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response
EMBO J.
2013
32: 1409-1424
|
| 11694518 |
Nikolopoulos SN et al.:
Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization
J. Biol. Chem.
2002
277: 1568-1575
|
| 10330411 |
Turner CE et al.:
Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling
J. Cell Biol.
1999
145: 851-863
|
| 23589845 |
Shah GN et al.:
Targeted mutagenesis of mitochondrial carbonic anhydrases VA and VB implicates both enzymes in ammonia detoxification and glucose metabolism
Proc. Natl. Acad. Sci. U.S.A.
2013
110: 7423-7428
|
| 25416956 |
Rolland T et al.:
A proteome-scale map of the human interactome network
Cell
2014
159: 1212-1226
|
| 15988023 |
Bois PR et al.:
Structural dynamics of alpha-actinin-vinculin interactions
Mol. Cell. Biol.
2005
25: 6112-6122
|
| 14517306 |
Miravet S et al.:
Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription
Mol. Cell. Biol.
2003
23: 7391-7402
|
| 12850569 |
Hou XY et al.:
Increased tyrosine phosphorylation of alpha(1C) subunits of L-type voltage-gated calcium channels and interactions among Src/Fyn, PSD-95 and alpha(1C) in rat hippocampus after transient brain ischemia
Brain Res.
2003
979: 43-50
|
| 16212417 |
Catimel B et al.:
Biosensor-based micro-affinity purification for the proteomic analysis of protein complexes
J. Proteome Res.
2005
4: 1646-1656
|
| 9405455 |
Hazan RB et al.:
Vinculin is associated with the E-cadherin adhesion complex
J. Biol. Chem.
1997
272
|
| 17620337 |
Kizhatil K et al.:
Ankyrin-G is a molecular partner of E-cadherin in epithelial cells and early embryos
J. Biol. Chem.
2007
282
|
| 11290418 |
Marfatia KA et al.:
Identification and characterization of the human MOG1 gene
Gene
2001
266: 45-56
|
| 15509562 |
Yang L et al.:
Ser1928 is a common site for Cav1.2 phosphorylation by protein kinase C isoforms
J. Biol. Chem.
2005
280: 207-214
|
| 1553557 |
Busch AE et al.:
An amino acid mutation in a potassium channel that prevents inhibition by protein kinase C
Science
1992
255: 1705-1707
|
| 11278781 |
Cui J et al.:
Analysis of the cyclic nucleotide binding domain of the HERG potassium channel and interactions with KCNE2
J. Biol. Chem.
2001
276
|
| 20462248 |
Zuo S et al.:
14-3-3 epsilon dynamically interacts with key components of mitogen-activated protein kinase signal module for selective modulation of the TNF-alpha-induced time course-dependent NF-kappaB activity
J. Proteome Res.
2010
9: 3465-3478
|
| 11953308 |
Kagan A et al.:
14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activity
EMBO J.
2002
21: 1889-1898
|
| 23434281 |
Ulbricht A et al.:
Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy
Curr. Biol.
2013
23: 430-435
|
| 23109059 |
Braissant O et al.:
Ammonia toxicity to the brain
J. Inherit. Metab. Dis.
2013
36: 595-612
|
| 20656926 |
Weber KS et al.:
Trpm4 differentially regulates Th1 and Th2 function by altering calcium signaling and NFAT localization
J. Immunol.
2010
185: 2836-2846
|
| 1633803 |
Indiveri C et al.:
Identification and purification of the ornithine/citrulline carrier from rat liver mitochondria
Eur. J. Biochem.
1992
207: 449-454
|
| 16602095 |
Scott CR et al.:
The genetic tyrosinemias
Am J Med Genet C Semin Med Genet
2006
142C: 121-126
|
| 10984438 |
Dechat T et al.:
Lamina-associated polypeptide 2alpha binds intranuclear A-type lamins
J. Cell. Sci.
2000
113: 3473-3484
|
| 22412018 |
Roux KJ et al.:
A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells
J. Cell Biol.
2012
196: 801-810
|
| 23311542 |
de Laet C et al.:
Recommendations for the management of tyrosinaemia type 1
Orphanet J Rare Dis
2013
8: 8
|
| 11792821 |
Lee KK et al.:
Distinct functional domains in emerin bind lamin A and DNA-bridging protein BAF
J. Cell. Sci.
2001
114: 4567-4573
|
| 21079765 |
de Morree A et al.:
Proteomic analysis of the dysferlin protein complex unveils its importance for sarcolemmal maintenance and integrity
PLoS ONE
2010
5
|
| 18677772 |
Deng XA et al.:
Ectopic expression of LIM-nebulette (LASP2) reveals roles in cell migration and spreading
Cell Motil. Cytoskeleton
2008
65: 827-840
|
| 23036342 |
Heylen E et al.:
Tyrosinemia Type III detected via neonatal screening: management and outcome
Mol. Genet. Metab.
2012
107: 605-607
|
| 23430973 |
Bertacchini J et al.:
The protein kinase Akt/PKB regulates both prelamin A degradation and Lmna gene expression
FASEB J.
2013
27: 2145-2155
|
| 16195397 |
Briere JJ et al.:
Mitochondrial succinate is instrumental for HIF1alpha nuclear translocation in SDHA-mutant fibroblasts under normoxic conditions
Hum. Mol. Genet.
2005
14: 3263-3269
|
| 20677779 |
Brownlee JM et al.:
Product analysis and inhibition studies of a causative Asn to Ser variant of 4-hydroxyphenylpyruvate dioxygenase suggest a simple route to the treatment of Hawkinsinuria
Biochemistry
2010
49: 7218-7226
|
| 17325032 |
Flugel D et al.:
Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner
Mol. Cell. Biol.
2007
27: 3253-3265
|
| 10781886 |
Lock EA et al.:
Tissue distribution of 2-(2-nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione (NTBC) and its effect on enzymes involved in tyrosine catabolism in the mouse
Toxicology
2000
144: 179-187
|
| 25474346 |
Gupta A et al.:
Ultrastructural Investigations in an Autosomal Recessively Inherited Case of Dyschromatosis Universalis Hereditaria
|
| 24530203 |
van Karnebeek CD et al. et al.:
Mitochondrial carbonic anhydrase VA deficiency resulting from CA5A alterations presents with hyperammonemia in early childhood
Am. J. Hum. Genet.
2014
94: 453-461
|
| 15722199 |
Chun J et al.:
The subcellular localization control of integrin linked kinase 1 through its protein-protein interaction with caveolin-1
Cell. Signal.
2005
17: 751-760
|
| 8538749 |
Hannigan GE et al.:
Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase
Nature
1996
379: 91-96
|
| 10022929 |
Tu Y et al.:
The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells
Mol. Cell. Biol.
1999
19: 2425-2434
|
| 24076469 |
Xu W et al.:
DHTKD1 is essential for mitochondrial biogenesis and function maintenance
FEBS Lett.
2013
587: 3587-3592
|
| 23141293 |
Danhauser K et al.:
DHTKD1 mutations cause 2-aminoadipic and 2-oxoadipic aciduria
Am. J. Hum. Genet.
2012
91: 1082-1087
|
| 23890588 |
Tondo M et al.:
Clinical, biochemical, molecular and therapeutic aspects of 2 new cases of 2-aminoadipic semialdehyde synthase deficiency
Mol. Genet. Metab.
2013
110: 231-236
|
| 22903658 |
Nesterova G et al.:
Cystinosis: the evolution of a treatable disease
Pediatr. Nephrol.
2013
28: 51-59
|
| 24401050 |
Klootwijk ED et al.:
Mistargeting of peroxisomal EHHADH and inherited renal Fanconis syndrome
N. Engl. J. Med.
2014
370: 129-138
|
| 20335586 |
Magen D et al.:
A loss-of-function mutation in NaPi-IIa and renal Fanconis syndrome
N. Engl. J. Med.
2010
362: 1102-1109
|
| 21596566 |
Grigoriev I et al.:
Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers
Curr. Biol.
2011
21: 967-974
|
| 20008558 |
Sakane A et al.:
Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L2
Mol. Cell. Biol.
2010
30: 1077-1087
|
| 12145326 |
Zhu X et al.:
Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects
Proc. Natl. Acad. Sci. U.S.A.
2002
99
|
| 12065665 |
Trani E et al.:
Isolation and characterization of VGF peptides in rat brain. Role of PC1/3 and PC2 in the maturation of VGF precursor
J. Neurochem.
2002
81: 565-574
|
| 20548951 |
Mattera L et al.:
The E1A-associated p400 protein modulates cell fate decisions by the regulation of ROS homeostasis
PLoS Genet.
2010
6
|
| 12447384 |
Beck S et al.:
Extraembryonic proteases regulate Nodal signalling during gastrulation
Nat. Cell Biol.
2002
4: 981-985
|
| 24860148 |
Wang Y et al.:
PCSK6 regulated by LH inhibits the apoptosis of human granulosa cells via activin A and TGFbeta2
J. Endocrinol.
2014
222: 151-160
|
| 24891332 |
Singaraja RR et al.:
Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans
J. Lipid Res.
2014
55: 1693-1701
|
| 24912412 |
Tate G et al.:
A novel mutation of the axonemal dynein heavy chain gene 5 (DNAH5) in a Japanese neonate with asplenia syndrome
Med Mol Morphol
2015
48: 116-122
|
| 9353118 |
Supp DM et al.:
Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice
Nature
1997
389: 963-966
|
| 25560148 |
Yuki R et al.:
Overexpression of zinc-finger protein 777 (ZNF777) inhibits proliferation at low cell density through down-regulation of FAM129A
J. Cell. Biochem.
2015
116: 954-968
|
| 22510990 |
Ji H et al.:
AKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosis
EMBO Rep.
2012
13: 554-560
|
| 20515759 |
Tang WB et al.:
Smad anchor for receptor activation (SARA) in TGF-beta signaling
Front Biosci (Elite Ed)
2010
2: 857-860
|
| 19740458 |
Etokebe GE et al.:
Family-with-sequence-similarity-46, member A (Fam46a) gene is expressed in developing tooth buds
Arch. Oral Biol.
2009
54: 1002-1007
|
| 22342342 |
Chen D et al.:
A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugate
Mol. Cell
2012
45: 629-641
|
| 21575909 |
Ogawa M et al.:
A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens
Cell Host Microbe
2011
9: 376-389
|
| 25431021 |
Tak H et al.:
miR-27 regulates mitochondrial networks by directly targeting the mitochondrial fission factor
Exp. Mol. Med.
2014
46: E123
|
| 23841699 |
Zhang H et al.:
Fibulin-2 deficiency attenuates angiotensin II-induced cardiac hypertrophy by reducing transforming growth factor-beta signalling
Clin. Sci.
2014
126: 275-288
|
| 24522256 |
Olijnyk D et al.:
Fibulin-2 is involved in early extracellular matrix development of the outgrowing mouse mammary epithelium
Cell. Mol. Life Sci.
2014
71: 3811-3828
|
| 15207333 |
Brooke RE et al.:
Association of potassium channel Kv3.4 subunits with pre- and post-synaptic structures in brainstem and spinal cord
Neuroscience
2004
4: 1001-1010
|
| 20566686 |
Sun Y et al.:
Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis
J. Cell Biol.
2010
189: 1157-1169
|
| 23802289 |
Vissing K et al.:
Differentiated mTOR but not AMPK signaling after strength vs endurance exercise in training-accustomed individuals
Scand J Med Sci Sports
2013
23: 355-366
|
| 22729928 |
Kofman AE et al.:
Transcriptional analysis of histone deacetylase family members reveal similarities between differentiating and aging spermatogonial stem cells
Stem Cell Rev
2013
9: 59-64
|
| 25751060 |
author information missing
MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation
J. Clin. Invest.
2015
125: 1509-1522
|
| 10523642 |
Ito M et al.:
JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway
Mol. Cell. Biol.
1999
19: 7539-7548
|
| 23408427 |
Bradley EW et al.:
Histone deacetylase 3 suppression increases PH domain and leucine-rich repeat phosphatase (Phlpp)1 expression in chondrocytes to suppress Akt signaling and matrix secretion
J. Biol. Chem.
2013
288: 9572-9582
|
| 25717001 |
Roboti P et al.:
The golgin GMAP-210 is required for efficient membrane trafficking in the early secretory pathway
J. Cell. Sci.
2015
128: 1595-1606
|
| 25473115 |
Sato K et al.:
Coupling of vesicle tethering and Rab binding is required for in vivo functionality of the golgin GMAP-210
Mol. Biol. Cell
2015
26: 537-553
|
| 19948655 |
Rossi AC et al.:
Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles
J. Physiol. (Lond.)
2010
588: 353-364
|
| 24663010 |
Sarkar A et al.:
Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior
Neuropsychopharmacology
2014
39: 2221-2232
|
| 24145169 |
Winbanks CE et al.:
The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass
J. Cell Biol.
2013
203: 345-357
|
| 11804585 |
Fischle W et al.:
Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR
Mol. Cell
2002
9: 45-57
|
| 20458742 |
Mace KE et al.:
TRUSS, TNF-R1, and TRPC ion channels synergistically reverse endoplasmic reticulum Ca2+ storage reduction in response to m1 muscarinic acetylcholine receptor signaling
J. Cell. Physiol.
2010
225: 444-453
|
| 26135885 |
Ma L et al.:
Effect of caloric restriction on the SIRT1/mTOR signaling pathways in senile mice
Brain Res. Bull.
2015
116: 67-72
|
| 21602272 |
Meruvu S et al.:
Regulation of adipocyte differentiation by the zinc finger protein ZNF638
J. Biol. Chem.
2011
286
|
| 25024404 |
Du C et al.:
The adipogenic transcriptional cofactor ZNF638 interacts with splicing regulators and influences alternative splicing
J. Lipid Res.
2014
55: 1886-1896
|
| 16899085 |
Latham CF et al.:
Molecular dissection of the Munc18c/syntaxin4 interaction: implications for regulation of membrane trafficking
Traffic
2006
7: 1408-1419
|
| 25955819 |
Cetrullo S et al.:
mTOR, AMPK, and Sirt1: Key Players in Metabolic Stress Management
Crit. Rev. Eukaryot. Gene Expr.
2015
25: 59-75
|
| 25344694 |
Lin B et al.:
Glycemic control with empagliflozin, a novel selective SGLT2 inhibitor, ameliorates cardiovascular injury and cognitive dysfunction in obese and type 2 diabetic mice
Cardiovasc Diabetol
2014
13: 148
|
| 21512283 |
Cerda A et al.:
Influence of polymorphisms and cholesterol-lowering treatment on SCARB1 mRNA expression
J. Atheroscler. Thromb.
2011
18: 640-651
|
| 15734838 |
Oh E et al.:
Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance
Diabetes
2005
54: 638-647
|
| 19009238 |
Habets DD et al.:
Munc18c is not rate-limiting for glucose and long-chain fatty acid uptake in the heart
Mol. Cell. Biochem.
2009
322: 81-86
|
| 26365275 |
Lopez-Moreno JA et al.:
Histone Deacetylase Gene Expression Following Binge Alcohol Consumption in Rats and Humans
Alcohol. Clin. Exp. Res.
2015
39: 1939-1950
|
| 24942484 |
Finegersh A et al.:
Acute ethanol alters multiple histone modifications at model gene promoters in the cerebral cortex
Alcohol. Clin. Exp. Res.
2014
38: 1865-1873
|
| 26317551 |
Carvalheira G et al.:
microRNA-106b-mediated down-regulation of C1orf24 expression induces apoptosis and suppresses invasion of thyroid cancer
Oncotarget
2015
6
|
| 26474739 |
Zhu M et al.:
ACAT1 regulates the dynamics of free cholesterols in plasma membrane which leads to the APP-alpha-processing alteration
|
| 11289722 |
Kyo K et al.:
Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohns disease
J. Hum. Genet.
2001
46: 5-20
|
| 16713569 |
Lim J et al.:
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration
Cell
2006
125: 801-814
|
| 12232777 |
Bosetti F et al.:
Chronic lithium downregulates cyclooxygenase-2 activity and prostaglandin E(2) concentration in rat brain
Mol. Psychiatry
2002
7: 845-850
|
| 15471909 |
Quiroz JA et al.:
Molecular effects of lithium
Mol. Interv.
2004
5: 259-272
|
| 21826702 |
Guo W et al.:
Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling
J. Neurosci. Res.
2011
89: 1723-1736
|
| 24277843 |
Zhang Q et al.:
Dynamic PIP2 interactions with voltage sensor elements contribute to KCNQ2 channel gating
Proc. Natl. Acad. Sci. U.S.A.
2013
50
|
| 23479625 |
Hudson BH et al.:
Role for cytoplasmic nucleotide hydrolysis in hepatic function and protein synthesis
Proc. Natl. Acad. Sci. U.S.A.
2013
110: 5040-5045
|
| 22252987 |
Ando-Akatsuka Y et al.:
Involvements of the ABC protein ABCF2 and alpha-actinin-4 in regulation of cell volume and anion channels in human epithelial cells
J. Cell. Physiol.
2012
227: 3498-3510
|
| 10037682 |
Chen RW et al.:
Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity
J. Biol. Chem.
1999
274: 6039-6042
|
| 12551726 |
Parthasarathy LK et al.:
Regional changes in rat brain inositol monophosphatase 1 (IMPase 1) activity with chronic lithium treatment
Prog. Neuropsychopharmacol. Biol. Psychiatry
2003
27: 55-60
|
| 7535800 |
Marples D et al.:
Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla
J. Clin. Invest.
1995
95: 1838-1845
|
| 23759441 |
Kim EC et al.:
Lithium treatment increases endothelial cell survival and autophagy in a mouse model of Fuchs endothelial corneal dystrophy
Br J Ophthalmol
2013
97: 1068-1073
|
| 17068342 |
Ohnishi T et al.:
Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1
J. Biol. Chem.
2007
1: 637-646
|
| 16186256 |
Sarkar S et al.:
Lithium induces autophagy by inhibiting inositol monophosphatase
J. Cell Biol.
2005
7: 1101-1111
|
| 10364240 |
Summers SA et al.:
The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism
J. Biol. Chem.
1999
274
|
| 3023372 |
author information missing
Effects of lithium ions on glycogen synthase and phosphorylase in rat hepatocytes
J. Biol. Chem.
1986
261
|
| 10675562 |
Yenush L et al.:
A novel target of lithium therapy
FEBS Lett.
2000
2-3: 321-325
|
| 10347153 |
Lopez-Coronado JM et al.:
A novel mammalian lithium-sensitive enzyme with a dual enzymatic activity, 3-phosphoadenosine 5-phosphate phosphatase and inositol-polyphosphate 1-phosphatase
J. Biol. Chem.
1999
23
|
| 15583009 |
Spiegelberg BD et al.:
Alteration of lithium pharmacology through manipulation of phosphoadenosine phosphate metabolism
J. Biol. Chem.
2005
280: 5400-5405
|
| 11361143 |
Minadeo N et al.:
Effect of Li+ upon the Mg2+-dependent activation of recombinant Gialpha1
Arch. Biochem. Biophys.
2001
388: 7-12
|
| 11500487 |
Masuda CA et al.:
Phosphoglucomutase is an in vivo lithium target in yeast
J. Biol. Chem.
2001
276
|
| 6211175 |
author information missing
Effects of lithium on the activities of phosphofructokinase and phosphoglucomutase and on glucose-1,6-diphosphate levels in rat muscles, brain and liver
Biochem. Pharmacol.
1982
31: 1025-1031
|
| 16259646 |
Csutora P et al.:
Lithium induces phosphoglucomutase activity in various tissues of rats and in bipolar patients
Int. J. Neuropsychopharmacol.
2006
9: 613-619
|
| 20637832 |
Souza Ade A et al.:
Glycogen synthesis in brain and astrocytes is inhibited by chronic lithium treatment
Neurosci. Lett.
2010
482: 128-132
|
| 8608143 |
Zhang R et al.:
Kinetics and mechanisms of activation and inhibition of porcine liver fructose-1,6-bisphosphatase by monovalent cations
Biochemistry
1996
35: 3038-3043
|
| 6282589 |
author information missing
Separation and characterisation of glycogen synthase kinase 3, glycogen synthase kinase 4 and glycogen synthase kinase 5 from rabbit skeletal muscle
Eur. J. Biochem.
1982
124: 21-35
|
| 11162580 |
Tian N et al.:
Lithium potentiates GSK-3beta activity by inhibiting phosphoinositide 3-kinase-mediated Akt phosphorylation
Biochem. Biophys. Res. Commun.
2014
450: 746-749
|
| 12796505 |
Zhang F et al.:
Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3
J. Biol. Chem.
2003
278
|
| 18191226 |
Beaulieu JM et al.:
A beta-arrestin 2 signaling complex mediates lithium action on behavior
Cell
2008
132: 125-136
|
| 22363263 |
Freland L et al.:
Inhibition of GSK3 by lithium, from single molecules to signaling networks
Front Mol Neurosci
2012
5: 14
|
| 19797860 |
Yoshioka W et al.:
Severe toxicity and cyclooxygenase (COX)-2 mRNA increase by lithium in the neonatal mouse kidney
J Toxicol Sci
2009
34: 519-525
|
| 17188038 |
Lochhead PA et al.:
A chaperone-dependent GSK3beta transitional intermediate mediates activation-loop autophosphorylation
Mol. Cell
2006
24: 627-633
|
| 23000340 |
Heinrich A et al.:
Lithium enhances CRTC oligomer formation and the interaction between the CREB coactivators CRTC and CBP--implications for CREB-dependent gene transcription
Cell. Signal.
2013
25: 113-125
|
| 7568043 |
Villeret V et al.:
Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase
Proc. Natl. Acad. Sci. U.S.A.
1995
92: 8916-8920
|
| 2559417 |
Lonati-Galligani M et al.:
Effect of in vivo lithium treatment on (-)isoproterenol-stimulated cAMP accumulation in lymphocytes of healthy subjects and patients with affective psychoses
Pharmacopsychiatry
1989
22: 241-245
|
| 175287 |
author information missing
Lithium inhibition of adrenaline-stimulated adenylate cyclase in humans
Nature
1976
259: 411-413
|
| 15631894 |
Parker MS et al.:
Lithium inhibits internalization and endosomal processing of both neuropeptide Y (NPY) Y1 and transferrin receptors
Neurosci. Lett.
2005
374: 43-46
|
| 16495377 |
Li Y et al.:
Development of lithium-induced nephrogenic diabetes insipidus is dissociated from adenylyl cyclase activity
J. Am. Soc. Nephrol.
2006
17: 1063-1072
|
| 24563318 |
Chung EJ et al.:
Lithium chloride inhibits TGF-beta1-induced myofibroblast transdifferentiation via PI3K/Akt pathway in cultured fibroblasts from Tenons capsule of the human eye
Biotechnol. Lett.
2014
36: 1217-1224
|
| 16682503 |
Chen CL et al.:
Lithium inhibits ceramide- and etoposide-induced protein phosphatase 2A methylation, Bcl-2 dephosphorylation, caspase-2 activation, and apoptosis
Mol. Pharmacol.
2006
70: 510-517
|
| 15992544 |
Shi J et al.:
Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes
Dev. Cell
2005
9: 99-108
|
| 17537472 |
Fuly AL et al.:
Lysophosphatidylcholine produced by the phospholipase A2 isolated from Lachesis muta snake venom modulates natural killer activity as a protein kinase C effector
Toxicon
2007
50: 400-410
|
| 25713101 |
Siddiqi S et al.:
Dietary and biliary phosphatidylcholine activates PKCzeta in rat intestine
J. Lipid Res.
2015
56: 859-870
|
| 19273501 |
Luiken JJ et al.:
Permissive action of protein kinase C-zeta in insulin-induced CD36- and GLUT4 translocation in cardiac myocytes
J. Endocrinol.
2009
201: 199-209
|
| 19761405 |
Bao JX et al.:
Activation of membrane NADPH oxidase associated with lysosome-targeted acid sphingomyelinase in coronary endothelial cells
Antioxid. Redox Signal.
2010
12: 703-712
|
| 16731764 |
Buggy JJ et al.:
CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo
Mol. Cancer Ther.
2006
5: 1309-1317
|
| 16337145 |
Zheng G et al.:
Acetylation and alternative splicing regulate ZNF76-mediated transcription
Biochem. Biophys. Res. Commun.
2006
339: 1069-1075
|
| 11960979 |
Saur D et al.:
Complex regulation of human neuronal nitric-oxide synthase exon 1c gene transcription. Essential role of Sp and ZNF family members of transcription factors
J. Biol. Chem.
2002
277
|
| 21151919 |
Hasan N et al.:
Fusogenic pairings of vesicle-associated membrane proteins (VAMPs) and plasma membrane t-SNAREs--VAMP5 as the exception
PLoS ONE
2010
5
|
| 15361834 |
Unoki M et al.:
ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain
Oncogene
2004
23: 7601-7610
|
| 10336434 |
Fasshauer D et al.:
Mixed and non-cognate SNARE complexes. Characterization of assembly and biophysical properties
J. Biol. Chem.
1999
274
|
| 12130530 |
Polgar J et al.:
Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion
Blood
2002
100: 1081-1083
|
| 12773094 |
Schraw TD et al.:
A role for Sec1/Munc18 proteins in platelet exocytosis
Biochem. J.
2003
374: 207-217
|
| 10646863 |
Hopfner R et al.:
ICBP90, a novel human CCAAT binding protein, involved in the regulation of topoisomerase IIalpha expression
Cancer Res.
2000
60: 121-128
|
| 19557002 |
Gordon DE et al.:
Coiled-coil interactions are required for post-Golgi R-SNARE trafficking
EMBO Rep.
2009
10: 851-856
|
| 11839770 |
Mallard F et al.:
Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform
J. Cell Biol.
2002
156: 653-664
|
| 15133481 |
Pryor PR et al.:
Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events
EMBO Rep.
2004
5: 590-595
|
| 15689499 |
Nakamura N et al.:
MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking
Mol. Biol. Cell
2005
16: 1696-1710
|
| 15312772 |
Muto Y et al.:
The structure and biochemical properties of the human spliceosomal protein U1C
J. Mol. Biol.
2004
341: 185-198
|
| 11350945 |
Makarova OV et al.:
The 65 and 110 kDa SR-related proteins of the U4/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomes
EMBO J.
2001
20: 2553-2563
|
| 15231748 |
Colland F et al.:
Functional proteomics mapping of a human signaling pathway
Genome Res.
2004
14: 1324-1332
|
| 25922075 |
Tremblay MG et al.:
Extended Synaptotagmin Interaction with the Fibroblast Growth Factor Receptor Depends on Receptor Conformation, Not Catalytic Activity
J. Biol. Chem.
2015
290
|
| 25249657 |
Chen PY et al.:
Fibroblast growth factor receptor 1 is a key inhibitor of TGFbeta signaling in the endothelium
Sci Signal
2014
7: RA90
|
| 21345218 |
Hein N et al.:
TGFbeta1 enhances MAD1 expression and stimulates promoter-bound Pol II phosphorylation: basic functions of C/EBP, SP and SMAD3 transcription factors
BMC Mol. Biol.
2011
12: 9
|
| 26383849 |
Garvilles RG et al.:
Dual Functions of the RFTS Domain of Dnmt1 in Replication-Coupled DNA Methylation and in Protection of the Genome from Aberrant Methylation
PLoS ONE
2015
10
|
| 10692465 |
Camerer E et al.:
Binding of factor VIIa to tissue factor on keratinocytes induces gene expression
J. Biol. Chem.
2000
275: 6580-6585
|
| 10708765 |
Lin MJ et al.:
One-codon alternative splicing of the CpG MTase Dnmt1 transcript in mouse somatic cells
FEBS Lett.
2000
469: 101-104
|
| 11063128 |
Aguirre-Arteta AM et al.:
Expression of an alternative Dnmt1 isoform during muscle differentiation
Cell Growth Differ.
2000
11: 551-559
|
| 18483244 |
Kurland JF et al.:
Myc-mediated transcriptional repression by recruitment of histone deacetylase
Cancer Res.
2008
68: 3624-3629
|
| 9724754 |
Liu B et al.:
Inhibition of Stat1-mediated gene activation by PIAS1
Proc. Natl. Acad. Sci. U.S.A.
1998
95
|
| 22623531 |
Toyoshima M et al.:
Functional genomics identifies therapeutic targets for MYC-driven cancer
Proc. Natl. Acad. Sci. U.S.A.
2012
109: 9545-9550
|
| 12652293 |
Bogdanov VY et al.:
Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein
Nat. Med.
2003
9: 458-462
|
| 7538109 |
Matsuda T et al.:
Activation of Fes tyrosine kinase by gp130, an interleukin-6 family cytokine signal transducer, and their association
J. Biol. Chem.
1995
270
|
| 10330178 |
Goyal RK et al.:
Ajuba, a novel LIM protein, interacts with Grb2, augments mitogen-activated protein kinase activity in fibroblasts, and promotes meiotic maturation of Xenopus oocytes in a Grb2- and Ras-dependent manner
Mol. Cell. Biol.
1999
19: 4379-4389
|
| 18950639 |
Sbrissa D et al.:
ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality
J. Mol. Biol.
2008
384: 766-779
|
| 19584092 |
author information missing
article information missing
|
| 26915802 |
author information missing
article information missing
|
| 9878061 |
author information missing
article information missing
|
| 8638164 |
author information missing
article information missing
|
| 20171186 |
author information missing
article information missing
|
| 8692842 |
author information missing
article information missing
|
| 14645450 |
Jurkat-Rott K et al.:
The impact of splice isoforms on voltage-gated calcium channel alpha1 subunits
J. Physiol. (Lond.)
2004
554: 609-619
|
| 11278576 |
author information missing
article information missing
|
| 21768092 |
author information missing
article information missing
|
| 19650649 |
author information missing
article information missing
|
| 10637234 |
author information missing
article information missing
|
| 27802322 |
author information missing
article information missing
|
| 26504085 |
Lee JH et al.:
Selenoprotein S-dependent Selenoprotein K Binding to p97(VCP) Protein Is Essential for Endoplasmic Reticulum-associated Degradation
J. Biol. Chem.
2015
290
|
| 15107821 |
Suzuki H et al.:
c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements
Oncogene
2004
23: 5068-5076
|
| 10549282 |
author information missing
article information missing
|
| 26345369 |
author information missing
article information missing
|
| 20644344 |
author information missing
article information missing
|
| 26270808 |
Abdel-Latif A et al.:
Lysophospholipids in coronary artery and chronic ischemic heart disease
Curr. Opin. Lipidol.
2015
26: 432-437
|
| 22359512 |
Demirkan A et al. et al.:
Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations
PLoS Genet.
2012
8
|
| 15117962 |
Samson T et al.:
The LIM-only proteins FHL2 and FHL3 interact with alpha- and beta-subunits of the muscle alpha7beta1 integrin receptor
J. Biol. Chem.
2004
279
|
| 24641900 |
Reyes-Gordillo K et al.:
Mechanisms of action of acetaldehyde in the up-regulation of the human alpha2(I) collagen gene in hepatic stellate cells: key roles of Ski, SMAD3, SMAD4, and SMAD7
Am. J. Pathol.
2014
184: 1458-1467
|
| 23555769 |
Jiang D et al.:
Elevated PLA2G7 gene promoter methylation as a gender-specific marker of aging increases the risk of coronary heart disease in females
PLoS ONE
2013
8
|
| 26438849 |
Zhao L et al.:
Elevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegeneration
Proc. Natl. Acad. Sci. U.S.A.
2015
112
|
| 19648650 |
Hornemann T et al.:
The SPTLC3 subunit of serine palmitoyltransferase generates short chain sphingoid bases
J. Biol. Chem.
2009
284
|
| 23714778 |
Saxe JP et al.:
Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline
EMBO J.
2013
32: 1869-1885
|
| 15465758 |
Obayashi M et al.:
Estrogen controls branched-chain amino acid catabolism in female rats
J. Nutr.
2004
134: 2628-2633
|
| 12538633 |
Jelinsky SA et al.:
Global transcription profiling of estrogen activity: estrogen receptor alpha regulates gene expression in the kidney
Endocrinology
2003
144: 701-710
|
| 11451741 |
Guo Z et al.:
Changes in expression of antioxidant enzymes affect cell-mediated LDL oxidation and oxidized LDL-induced apoptosis in mouse aortic cells
Arterioscler. Thromb. Vasc. Biol.
2001
21: 1131-1138
|
| 27880078 |
Lockridge AD et al.:
Serine racemase is expressed in islets and contributes to the regulation of glucose homeostasis
Islets
2016
8: 195-206
|
| 7589426 |
Volz A et al.:
Molecular cloning, functional expression, and signal transduction of the GIP-receptor cloned from a human insulinoma
FEBS Lett.
1995
373: 23-29
|
| 23526982 |
Schwartz C et al.:
Seasonal and regional differences in gene expression in the brain of a hibernating mammal
PLoS ONE
2013
8
|
| 25639459 |
Hull J et al.:
New insights into the role of the branched-chain aminotransferase proteins in the human brain
J. Neurosci. Res.
2015
93: 987-998
|
| 26506382 |
Liao CC et al.:
Proteomics Analysis to Identify and Characterize the Molecular Signatures of Hepatic Steatosis in Ovariectomized Rats as a Model of Postmenopausal Status
Nutrients
2015
7: 8752-8766
|
| 15802376 |
Monroe DG et al.:
Estrogen receptor alpha and beta heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2OS osteosarcoma cells
Mol. Endocrinol.
2005
19: 1555-1568
|
| 20647306 |
Ueno T et al.:
Enhancement of procollagen biosynthesis by p180 through augmented ribosome association on the endoplasmic reticulum in response to stimulated secretion
J. Biol. Chem.
2010
285
|
| 16365084 |
Brosnan JT et al.:
Branched-chain amino acids: enzyme and substrate regulation
J. Nutr.
2006
136: 207S-211S
|
| 27049024 |
Hirsova P et al.:
Lipotoxic lethal and sublethal stress signaling in hepatocytes: relevance to NASH pathogenesis
J. Lipid Res.
2016
57: 1758-1770
|
| 7492774 |
Yuan Y et al.:
An essential role for lysophosphatidylcholine in the inhibition of platelet aggregation by secretory phospholipase A2
Blood
1995
86: 4166-4174
|
| 23064749 |
Giannuzzi G et al.:
Evolutionary dynamism of the primate LRRC37 gene family
Genome Res.
2013
23: 46-59
|
| 11112705 |
Nagamatsu S et al.:
Localization of cellubrevin-related peptide, endobrevin, in the early endosome in pancreatic beta cells and its physiological function in exo-endocytosis of secretory granules
J. Cell. Sci.
2001
114: 219-227
|
| 11306568 |
Liberati NT et al.:
An essential role for Mad homology domain 1 in the association of Smad3 with histone deacetylase activity*
J. Biol. Chem.
2001
276
|
| 15792362 |
Venardos K et al.:
Effects of dietary selenium on post-ischemic expression of antioxidant mRNA
Mol. Cell. Biochem.
2005
270: 131-138
|
| 22913986 |
Lee YJ et al.:
Circadian regulation of low density lipoprotein receptor promoter activity by CLOCK/BMAL1, Hes1 and Hes6
Exp. Mol. Med.
2012
44: 642-652
|
| 1695905 |
Kayano T et al.:
Human facilitative glucose transporters. Isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose tissue and an unusual glucose transporter pseudogene-like sequence (GLUT6)
J. Biol. Chem.
1990
265
|
| 1854365 |
Uchida E et al.:
Effect of insulin, glucagon or dexamethasone on the production of apolipoprotein A-IV in cultured rat hepatocytes
Atherosclerosis
1991
87: 195-202
|
| 22952936 |
Xu YQ et al.:
Diurnal variation of hepatic antioxidant gene expression in mice
PLoS ONE
2012
7
|
| 12091390 |
Zhang Y et al.:
Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex
J. Biol. Chem.
2002
277
|
| 19239128 |
Srivastava N et al.:
Dietary cholesterol and estrogen administration elevate brain apolipoprotein E in mice by different mechanisms
Indian J. Biochem. Biophys.
2008
45: 410-415
|
| 15033916 |
Nathan BP et al.:
Estrogen facilitates neurite extension via apolipoprotein E in cultured adult mouse cortical neurons
Endocrinology
2004
145: 3065-3073
|
| 1984576 |
Kushwaha RS et al.:
Metabolic regulation of plasma apolipoprotein E by estrogen and progesterone in the baboon (Papio sp)
Metab. Clin. Exp.
1991
40: 93-100
|
| 23675510 |
Zabouri N et al.:
Calcium channel-dependent molecular maturation of photoreceptor synapses
PLoS ONE
2013
8
|
| 27376484 |
Chen Y et al.:
CLOCK-BMAL1 regulate the cardiac L-type calcium channel subunit CACNA1C through PI3K-Akt signaling pathway
Can. J. Physiol. Pharmacol.
2016
94: 1023-1032
|
| 9126968 |
Tari AM et al.:
GRB2: a pivotal protein in signal transduction
Semin. Oncol.
2001
28: 142-147
|
| 12598680 |
Segal RA et al.:
Selectivity in neurotrophin signaling: theme and variations
Annu. Rev. Neurosci.
2003
26: 299-330
|
| 28213521 |
Wills MK et al.:
Signalling Adaptor ShcD Suppresses Erk Phosphorylation Distal to the Ret and Trk Neurotrophic Receptors
|
| 17178724 |
Laramee M et al.:
The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation
J. Biol. Chem.
2007
282: 7758-7769
|
| 23643389 |
Hao Y et al.:
Gain of interaction with IRS1 by p110alpha-helical domain mutants is crucial for their oncogenic functions
Cancer Cell
2013
23: 583-593
|
| 28303424 |
Clayton PT et al.:
Inherited disorders of transition metal metabolism: an update
|
| 27956349 |
Koike A et al.:
Inhibitory effect of divalent metal cations on zinc uptake via mouse Zrt-/Irt-like protein 8 (ZIP8)
Life Sci.
2017
173: 80-85
|
| 8360145 |
Marshall BA et al.:
Germline manipulation of glucose homeostasis via alteration of glucose transporter levels in skeletal muscle
J. Biol. Chem.
1993
268
|
| 8702680 |
Milstien S et al.:
Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP
J. Biol. Chem.
1996
271
|
| 12946355 |
Wolf M et al.:
Visualization of the domain structure of an L-type Ca2+ channel using electron cryo-microscopy
J. Mol. Biol.
2003
332: 171-182
|
| 26245899 |
Georgiou DK et al.:
Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism
J. Biol. Chem.
2015
290
|
| 25772847 |
Laing EE et al.:
Exploiting human and mouse transcriptomic data: Identification of circadian genes and pathways influencing health
Bioessays
2015
37: 544-556
|
| 11744719 |
Reschly EJ et al.:
Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution
J. Biol. Chem.
2002
277: 9645-9654
|
| 10722751 |
Clay MA et al.:
Formation of spherical, reconstituted high density lipoproteins containing both apolipoproteins A-I and A-II is mediated by lecithin:cholesterol acyltransferase
J Biol Chem
2000
275: 9019-9025
|
| 16204232 |
Maric J et al.:
Intracellular lipidation of newly synthesized apolipoprotein A-I in primary murine hepatocytes
J. Biol. Chem.
2005
280
|
| 11991719 |
Ritter M et al.:
Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I
Genomics
2002
79: 693-702
|
| 15174051 |
Zhou M et al.:
An investigation into the human serum interactome
Electrophoresis
2004
25: 1289-1298
|
| 3104518 |
author information missing
Distribution and localization of lecithin:cholesterol acyltransferase and cholesteryl ester transfer activity in A-I-containing lipoproteins
J. Lipid Res.
1986
27: 1135-1144
|
| 8502995 |
Harada T et al.:
Feedback regulation mechanisms for the control of GTP cyclohydrolase I activity
Science
1993
260: 1507-1510
|
| 10946021 |
Escola-Gil JC et al.:
Expression of human apolipoprotein A-II in apolipoprotein E-deficient mice induces features of familial combined hyperlipidemia
J. Lipid Res.
2000
41: 1328-1338
|
| 25075435 |
Aslibekyan S et al.:
PRKCZ methylation is associated with sunlight exposure in a North American but not a Mediterranean population
Chronobiol. Int.
2014
31: 1034-1040
|
| 26241318 |
Fitzpatrick PF et al.:
Structural insights into the regulation of aromatic amino acid hydroxylation
Curr. Opin. Struct. Biol.
2015
35: 1-6
|
| 23622399 |
Hoffmann GF et al.:
Defects in amino acid catabolism and the urea cycle
Handb Clin Neurol
2013
113: 1755-1773
|
| 27513937 |
Yano S et al.:
Evaluation of Tetrahydrobiopterin Therapy with Large Neutral Amino Acid Supplementation in Phenylketonuria: Effects on Potential Peripheral Biomarkers, Melatonin and Dopamine, for Brain Monoamine Neurotransmitters
PLoS ONE
2016
11
|
| 19191004 |
van Spronsen FJ et al.:
Brain dysfunction in phenylketonuria: is phenylalanine toxicity the only possible cause? }, authors { names std { { name ml van Spronsen FJ, affil str Beatrix Childrens Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. f.j.van.spronsen@bkk.umcg.nl }, { name ml Hoeksma M }, { name ml Reijngoud DJ } } }, from journal { title { iso-jta J. Inherit. Metab. Dis
J. Inherit. Metab. Dis.
2009
32: 46-51
|
| 24857519 |
Yano S et al.:
Melatonin and dopamine as biomarkers to optimize treatment in phenylketonuria: effects of tryptophan and tyrosine supplementation
J. Pediatr.
2014
165: 184-189
|
| 10634821 |
Hegele RA et al.:
The private hepatocyte nuclear factor-1alpha G319S variant is associated with plasma lipoprotein variation in Canadian Oji-Cree
Arterioscler. Thromb. Vasc. Biol.
2000
20: 217-222
|
| 11229886 |
Zannis VI et al.:
Transcriptional regulation of the human apolipoprotein genes
Front. Biosci.
2001
6: D456-D504
|
| 14216443 |
author information missing
TYROSINE HYDROXYLASE. THE INITIAL STEP IN NOREPINEPHRINE BIOSYNTHESIS
J. Biol. Chem.
1964
239: 2910-2917
|
| 8204666 |
Schallreuter KU et al.:
Defective tetrahydrobiopterin and catecholamine biosynthesis in the depigmentation disorder vitiligo
Biochim. Biophys. Acta
1994
1226: 181-192
|
| 26425393 |
Schuck PF et al.:
Phenylketonuria Pathophysiology: on the Role of Metabolic Alterations
Aging Dis
2015
6: 390-399
|
| 9352 |
author information missing
Identity of kynurenine: pyruvate aminotransferase with histidine: pyruvate aminotransferase
Hoppe-Seylers Z. Physiol. Chem.
1976
5: 649-656
|
| 24607329 |
Nagasaka H et al.:
Changes of lipoproteins in phenylalanine hydroxylase-deficient children during the first year of life
Clin. Chim. Acta
2014
433: 1-4
|
| 10956425 |
Shefer S et al.:
Is there a relationship between 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and forebrain pathology in the PKU mouse? }, authors { names std { { name ml Shefer S, affil str Department of Medicine/Liver Center, UMDNJ-New Jersey Medical School, Newark, NJ, USA
J. Neurosci. Res.
2000
61: 549-563
|
| 987681 |
author information missing
Inhibition of pyruvate oxidation by skeletal muscle mitochondria by phenylpyruvate
Acta Biochim. Pol.
1976
23: 85-92
|
| 28419892 |
Muenchhoff J et al. et al.:
Plasma apolipoproteins and physical and cognitive health in very old individuals
Neurobiol Aging
2017
55: 49-60
|
| 10635003 |
Heigenhauser GJ et al.:
Role of pyruvate dehydrogenase in lactate production in exercising human skeletal muscle
Adv. Exp. Med. Biol.
1999
474: 205-218
|
| 17401656 |
Yu YG et al.:
Effects of phenylalanine and its metabolites on cytoplasmic free calcium in cortical neurons
Neurochem. Res.
2007
32: 1292-1301
|
| 15077723 |
Jump DB et al.:
Fatty acid regulation of gene transcription
Crit Rev Clin Lab Sci
2004
41: 41-78
|
| 28373690 |
Ryan DP et al.:
A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice
|
| 16342170 |
Li C et al.:
17beta-estradiol (betaE2) protects human retinal Muller cell against oxidative stress in vitro: evaluation of its effects on gene expression by cDNA microarray
Glia
2006
53: 392-400
|
| 26807510 |
Elshorbagy AK et al.:
Serum S-adenosylmethionine, but not methionine, increases in response to overfeeding in humans
Nutr Diabetes
2016
6: E192
|
| 22724053 |
Inoue-Choi M et al.:
One-carbon metabolism nutrient status and plasma S-adenosylmethionine concentrations in middle-aged and older Chinese in Singapore
Int J Mol Epidemiol Genet
2012
3: 160-173
|
| 17116003 |
Lundasen T et al.:
Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man
J. Intern. Med.
2006
260: 530-536
|
| 15564327 |
Stayrook KR et al.:
Regulation of carbohydrate metabolism by the farnesoid X receptor
Endocrinology
2005
146: 984-991
|
| 25392541 |
Stukas S et al.:
Intravenously injected human apolipoprotein A-I rapidly enters the central nervous system via the choroid plexus
J Am Heart Assoc
2014
3
|
| 7896852 |
Kilbourne EJ et al.:
Involvement of early growth response factor Egr-1 in apolipoprotein AI gene transcription
J. Biol. Chem.
1995
270: 7004-7010
|
| 27404023 |
Shavva VS et al.:
Insulin-Mediated Downregulation of Apolipoprotein A-I Gene in Human Hepatoma Cell Line HepG2: The Role of Interaction Between FOXO1 and LXRbeta Transcription Factors
J Cell Biochem
2017
118: 382-396
|
| 27174096 |
Mahley RW et al.:
Central Nervous System Lipoproteins: ApoE and Regulation of Cholesterol Metabolism
Arterioscler. Thromb. Vasc. Biol.
2016
36: 1305-1315
|
| 3989387 |
et al.:
The in vitro formation of HDL2 during the action of LCAT: the role of triglyceride-rich lipoproteins
J. Lipid Res.
1985
26: 273-282
|
| 26813964 |
Shavva VS et al.:
PPARgamma Represses Apolipoprotein A-I Gene but Impedes TNFalpha-Mediated ApoA-I Downregulation in HepG2 Cells
J. Cell. Biochem.
2016
117: 2010-2022
|
| 11243724 |
Infante JP et al.:
Impaired arachidonic (20:4n-6) and docosahexaenoic (22:6n-3) acid synthesis by phenylalanine metabolites as etiological factors in the neuropathology of phenylketonuria
Mol. Genet. Metab.
2001
72: 185-198
|
| 17154544 |
Huuskonen J et al.:
Liver X receptor inhibits the synthesis and secretion of apolipoprotein A1 by human liver-derived cells
Biochemistry
2006
45
|
| 15824121 |
McCarthy TC et al.:
Vitamin D receptor-dependent regulation of colon multidrug resistance-associated protein 3 gene expression by bile acids
J. Biol. Chem.
2005
280
|
| 12145154 |
Stulnig TM et al.:
Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity
Diabetes
2002
51: 2426-2433
|
| 12876624 |
Xia H et al.:
Oxysterols suppress constitutive fibrinogen expression
Thromb. Haemost.
2003
90: 43-51
|
| 23897684 |
Chiang JY et al.:
Bile acid metabolism and signaling
Compr Physiol
2013
3: 1191-1212
|
| 17452648 |
Ogawa Y et al.:
BetaKlotho is required for metabolic activity of fibroblast growth factor 21
Proc. Natl. Acad. Sci. U.S.A.
2007
104: 7432-7437
|
| 27545319 |
Huang C et al.:
Identification of functional farnesoid X receptors in brain neurons
FEBS Lett.
2016
590: 3233-3242
|
| 27350042 |
Dekkers KF et al.:
Blood lipids influence DNA methylation in circulating cells
Genome Biol.
2016
17: 138
|
| 19996111 |
Ogundare M et al.:
Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain?
J. Biol. Chem.
2010
285: 4666-4679
|
| 22661206 |
Takahashi-Iniguez T et al.:
Role of vitamin B12 on methylmalonyl-CoA mutase activity
J Zhejiang Univ Sci B
2012
13: 423-437
|
| 19130896 |
Paula-Lima AC et al.:
Human apolipoprotein A-I binds amyloid-beta and prevents Abeta-induced neurotoxicity
Int. J. Biochem. Cell Biol.
2009
41: 1361-1370
|
| 24685634 |
Shih YH et al.:
Apolipoprotein C-III is an amyloid-beta-binding protein and an early marker for Alzheimers disease
J. Alzheimers Dis.
2014
41: 855-865
|
| 21356380 |
Cui Y et al.:
Genetic ablation of apolipoprotein A-IV accelerates Alzheimers disease pathogenesis in a mouse model
Am. J. Pathol.
2011
178: 1298-1308
|
| 22398376 |
Martinez E et al.:
Amyloid-beta25-35 induces apolipoprotein D Synthesis and growth arrest in HT22 hippocampal cells
J. Alzheimers Dis.
2012
30: 233-244
|
| 28572511 |
Fettelschoss V et al.:
Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B12-trafficking proteins ABCD4 and LMBD1
|
| 11441143 |
Koch S et al.:
Characterization of four lipoprotein classes in human cerebrospinal fluid
J. Lipid Res.
2001
42: 1143-1151
|
| 24938018 |
author information missing
Apolipoprotein B-48: a unique marker of chylomicron metabolism
Adv Clin Chem
2014
64: 117-177
|
| 23415653 |
Quadros EV et al.:
Cellular uptake of cobalamin: transcobalamin and the TCblR/CD320 receptor
Biochimie
2013
95: 1008-1018
|
| 9572993 |
Kozyraki R et al.:
The human intrinsic factor-vitamin B12 receptor, cubilin: molecular characterization and chromosomal mapping of the gene to 10p within the autosomal recessive megaloblastic anemia (MGA1) region
Blood
1998
91: 3593-3600
|
| 14576052 |
Fyfe JC et al.:
The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless
Blood
2004
103: 1573-1579
|
| 18779389 |
Quadros EV et al.:
The protein and the gene encoding the receptor for the cellular uptake of transcobalamin-bound cobalamin
Blood
2009
113: 186-192
|
| 19897579 |
Beedholm-Ebsen R et al.:
Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin
Blood
2010
115: 1632-1639
|
| 27771510 |
Bassila C et al.:
Methionine synthase and methionine synthase reductase interact with MMACHC and with MMADHC
Biochim. Biophys. Acta
2017
1863: 103-112
|
| 27771510 |
author information missing
article information missing
|
| 27456980 |
Kawaguchi K et al.:
Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1
Sci Rep
2016
6: 30183
|
| 24078630 |
Tseng LT et al.:
LMBD1 protein serves as a specific adaptor for insulin receptor internalization
J. Biol. Chem.
2013
288
|
| 28672200 |
Jain RB et al.:
Impact of smoking on the observed levels of apolipoprotein B: Data from NHANES 2007-2012
Environ. Toxicol. Pharmacol.
2017
53: 227-233
|
| 19049969 |
Liang D et al.:
Protein CutA undergoes an unusual transfer into the secretory pathway and affects the folding, oligomerization, and secretion of acetylcholinesterase
J. Biol. Chem.
2009
284: 5195-5207
|
| 27013657 |
Watkins HA et al.:
Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties
J. Biol. Chem.
2016
291
|
| 17894889 |
Penning TM et al.:
The aldo-keto reductases (AKRs): Overview
Chem. Biol. Interact.
2015
234: 236-246
|
| 20410017 |
Das SK et al.:
Distinct gene expression profiles characterize cellular responses to palmitate and oleate
J. Lipid Res.
2010
51: 2121-2131
|
| 15314288 |
Beeharry N et al.:
Fatty acid protection from palmitic acid-induced apoptosis is lost following PI3-kinase inhibition
Apoptosis
2004
9: 599-607
|
| 26373698 |
Janecke AR et al.:
The phenotype of the musculocontractural type of Ehlers-Danlos syndrome due to CHST14 mutations
Am. J. Med. Genet. A
2016
170A: 103-115
|
| 1904868 |
Chambaz J et al.:
Promoter elements and factors required for hepatic transcription of the human ApoA-II gene
J. Biol. Chem.
1991
266
|
| 15326035 |
Fagan AM et al.:
Comparison of analytical platforms for cerebrospinal fluid measures of beta-amyloid 1-42, total tau, and p-tau181 for identifying Alzheimer disease amyloid plaque pathology
Arch. Neurol.
2011
68: 1137-1144
|
| 28179877 |
Lekholm E et al.:
Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability
Front Mol Neurosci
2017
10: 11
|
| 26709097 |
Xie X et al.:
Tumor suppressor RIZ1 in obesity and the PI3K/AKT/mTOR pathway
Obesity (Silver Spring)
2016
24: 389-397
|
| 24503482 |
Kakarala KK et al.:
Sequence-structure based phylogeny of GPCR Class A Rhodopsin receptors
Mol. Phylogenet. Evol.
2014
74: 66-96
|
| 12815059 |
He X et al.:
Purification and characterization of recombinant, human acid ceramidase. Catalytic reactions and interactions with acid sphingomyelinase
J. Biol. Chem.
2003
278
|
| 22002062 |
Okumoto K et al.:
Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid beta-oxidation in peroxisomal matrix
J. Biol. Chem.
2011
286
|
| 23459139 |
Mizuno Y et al.:
Tysnd1 deficiency in mice interferes with the peroxisomal localization of PTS2 enzymes, causing lipid metabolic abnormalities and male infertility
PLoS Genet.
2013
9
|
| 25938220 |
author information missing
The molecular medicine of acid ceramidase
Biol. Chem.
2015
396: 759-765
|
| 16179341 |
Garuti R et al.:
The modular adaptor protein autosomal recessive hypercholesterolemia (ARH) promotes low density lipoprotein receptor clustering into clathrin-coated pits
J. Biol. Chem.
2005
280
|
| 21444685 |
Kang RS et al.:
ARH cooperates with AP-1B in the exocytosis of LDLR in polarized epithelial cells
J. Cell Biol.
2011
193: 51-60
|
| 22841715 |
Davies SM et al.:
MRPS27 is a pentatricopeptide repeat domain protein required for the translation of mitochondrially encoded proteins
FEBS Lett.
2012
586: 3555-3561
|
| 22493286 |
Choe J et al.:
Translation initiation on mRNAs bound by nuclear cap-binding protein complex CBP80/20 requires interaction between CBP80/20-dependent translation initiation factor and eukaryotic translation initiation factor 3g
J. Biol. Chem.
2012
287
|
| 24080033 |
Kim JT et al.:
Caspase-mediated cleavage and DNase activity of the translation initiation factor 3, subunit G (eIF3g)
FEBS Lett.
2013
587: 3668-3674
|
| 27462815 |
author information missing
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
Nature
2016
536: 96-99
|
| 26448619 |
Zielinska M et al.:
Induction of inducible nitric oxide synthase expression in ammonia-exposed cultured astrocytes is coupled to increased arginine transport by upregulated y(+)LAT2 transporter
J. Neurochem.
2015
135: 1272-1281
|
| 19643181 |
Nicholson TB et al.:
The physiological and pathophysiological role of PRMT1-mediated protein arginine methylation
Pharmacol. Res.
2009
60: 466-474
|
| 12515826 |
Ehehalt R et al.:
Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts
J. Cell Biol.
2003
160: 113-123
|
| 26476183 |
Sukocheva O et al.:
Sphingosine-1-phosphate receptor 1 transmits estrogens effects in endothelial cells
Steroids
2015
104: 237-245
|
| 16309971 |
Jia SJ et al.:
Lysophosphatidylcholine-induced elevation of asymmetric dimethylarginine level by the NADPH oxidase pathway in endothelial cells
Vascul. Pharmacol.
2006
44: 143-148
|
| 17522181 |
Gomez-Brouchet A et al.:
Critical role for sphingosine kinase-1 in regulating survival of neuroblastoma cells exposed to amyloid-beta peptide
Mol. Pharmacol.
2007
72: 341-349
|
| 22178795 |
Gualtieri M et al.:
Gene expression profiling of A549 cells exposed to Milan PM2.5
Toxicol. Lett.
2012
209: 136-145
|
| 27690135 |
Cattie DJ et al.:
Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans
PLoS Genet.
2016
12
|
| 17004324 |
Turro S et al.:
Identification and characterization of associated with lipid droplet protein 1: A novel membrane-associated protein that resides on hepatic lipid droplets
Traffic
2006
7: 1254-1269
|
| 23313215 |
Thomas A et al.:
Changes in the hepatic mitochondrial and membrane proteome in mice fed a non-alcoholic steatohepatitis inducing diet
J Proteomics
2013
80: 107-122
|
| 28473467 |
Mehta MB et al.:
Hepatic protein phosphatase 1 regulatory subunit 3B (Ppp1r3b) promotes hepatic glycogen synthesis and thereby regulates fasting energy homeostasis
J. Biol. Chem.
2017
292
|
| 15247905 |
Yordy JS et al.:
SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion
Oncogene
2004
23: 6654-6665
|
| 15592518 |
Yordy JS et al.:
SP100 inhibits ETS1 activity in primary endothelial cells
Oncogene
2005
24: 916-931
|
| 20660080 |
Yang CC et al.:
Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation
RNA
2010
16: 1748-1759
|
| 17185417 |
Guo X et al.:
The zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNA
Proc Natl Acad Sci U S A
2007
104: 151-156
|
| 10421373 |
Orphanides G et al.:
The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins
Nature
1999
400: 284-288
|
| 21969370 |
Winkler DD et al.:
Histone chaperone FACT coordinates nucleosome interaction through multiple synergistic binding events
J. Biol. Chem.
2011
286
|
| 14960569 |
Leonoudakis D et al.:
A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels
J. Biol. Chem.
2004
279
|
| 25504030 |
Huang T et al.:
PCSK7 genotype modifies effect of a weight-loss diet on 2-year changes of insulin resistance: the POUNDS LOST trial
Diabetes Care
2015
38: 439-444
|
| 9045697 |
Duguay SJ et al.:
Processing of wild-type and mutant proinsulin-like growth factor-IA by subtilisin-related proprotein convertases
J. Biol. Chem.
1997
272: 6663-6670
|
| 7827621 |
Chao HM et al.:
The effects of aging and hormonal manipulation on amyloid precursor protein APP695 mRNA expression in the rat hippocampus
J. Neuroendocrinol.
1994
6: 517-521
|
| 23530041 |
Russo SB et al.:
Myristate-derived d16:0 sphingolipids constitute a cardiac sphingolipid pool with distinct synthetic routes and functional properties
J. Biol. Chem.
2013
288
|
| 11240164 |
Herrero A et al.:
Effect of the degree of fatty acid unsaturation of rat heart mitochondria on their rates of H2O2 production and lipid and protein oxidative damage
Mech. Ageing Dev.
2001
122: 427-443
|
| 22355651 |
Houtkooper RH et al.:
The metabolic footprint of aging in mice
Sci Rep
2011
1: 134
|
| 26955889 |
Taylor SE et al.:
Identification of Human Juvenile Chondrocyte-Specific Factors that Stimulate Stem Cell Growth
Tissue Eng Part A
2016
22: 645-653
|
| 24816252 |
Shin SY et al.:
An atlas of genetic influences on human blood metabolites
Nat. Genet.
2014
46: 543-550
|
| 24114175 |
Pajor AM et al.:
Sodium-coupled dicarboxylate and citrate transporters from the SLC13 family
Pflugers Arch.
2014
466: 119-130
|
| 3783793 |
author information missing
Peroxidases induced in rat uterus by estrogen administration. II. Cytochemical and biochemical heterogeneity
J. Submicrosc. Cytol.
1986
18: 683-690
|
| 1473209 |
Huang PL et al.:
[Effects of sex hormones on large bowel carcinogenesis induced by 1,2-dimethylhydrazine in Sprague-Dawley rats]
Zhonghua Bing Li Xue Za Zhi
1992
21: 232-234
|
| 19251691 |
Hagen N et al.:
Subcellular origin of sphingosine 1-phosphate is essential for its toxic effect in lyase-deficient neurons
J. Biol. Chem.
2009
284
|
| 7057619 |
author information missing
Effect of carnitine on serum HDL-cholesterol: report of two cases
Johns Hopkins Med J
1982
150: 51-54
|
| 2031874 |
Hulsmann WC et al.:
Biochemical profile of propionyl-L-carnitine
Cardiovasc Drugs Ther
1991
5: Suppl 1 7-9
|
| 11297421 |
Koldamova RP et al.:
Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity
Biochemistry
2001
40: 3553-3560
|
| 23372797 |
Chung KY et al.:
Identification of GPCR-interacting cytosolic proteins using HDL particles and mass spectrometry-based proteomic approach
PLoS ONE
2013
8
|
| 11278817 |
Zheng XL et al.:
Epidermal growth factor induction of apolipoprotein A-I is mediated by the Ras-MAP kinase cascade and Sp1
J. Biol. Chem.
2001
276
|
| 15533931 |
Spagnuolo MS et al.:
Assignment of the binding site for haptoglobin on apolipoprotein A-I
J. Biol. Chem.
2005
280: 1193-1198
|
| 19758344 |
Cigliano L et al.:
Haptoglobin binds the antiatherogenic protein apolipoprotein E - impairment of apolipoprotein E stimulation of both lecithin:cholesterol acyltransferase activity and cholesterol uptake by hepatocytes
FEBS J.
2009
276: 6158-6171
|
| 12614163 |
Lam JK et al.:
Insulin induction of apolipoprotein AI, role of Sp1
Biochemistry
2003
42: 2680-2690
|
| 8202496 |
Thorngate FE et al.:
Insulin promotes the biosynthesis and secretion of apolipoprotein B-48 by altering apolipoprotein B mRNA editing
Proc. Natl. Acad. Sci. U.S.A.
1994
91: 5392-5396
|
| 11551957 |
Liang CP et al.:
Transcriptional profiling reveals global defects in energy metabolism, lipoprotein, and bile acid synthesis and transport with reversal by leptin treatment in ob/ob mouse liver
J. Biol. Chem.
2001
276
|
| 15734841 |
Duivenvoorden I et al.:
Apolipoprotein C3 deficiency results in diet-induced obesity and aggravated insulin resistance in mice
Diabetes
2005
54: 664-671
|
| 11856346 |
Matko J et al.:
GPI-microdomains (membrane rafts) and signaling of the multi-chain interleukin-2 receptor in human lymphoma/leukemia T cell lines
Eur. J. Biochem.
2002
269: 1199-1208
|
| 21508255 |
Arthur JR et al.:
Filipin recognizes both GM1 and cholesterol in GM1 gangliosidosis mouse brain
J. Lipid Res.
2011
52: 1345-1351
|
| 6460340 |
author information missing
Degradation of the apoprotein A-I polypeptide chain of human high density lipoprotein by human plasmin
Thromb. Res.
1981
24: 151-156
|
| 15033978 |
Liz MA et al.:
Transthyretin, a new cryptic protease
J. Biol. Chem.
2004
279
|
| 19819722 |
Wang L et al.:
Apolipoprotein A-I inhibits chemotaxis, adhesion, activation of THP-1 cells and improves the plasma HDL inflammatory index
Cytokine
2010
49: 194-200
|
| 25668017 |
Xu H et al.:
Lysosomal physiology
Annu. Rev. Physiol.
2015
77: 57-80
|
| 26201081 |
Lasrich D et al.:
Apolipoprotein E promotes lipid accumulation and differentiation in human adipocytes
Exp. Cell Res.
2015
337: 94-102
|
| 11456487 |
Yamaguchi I et al.:
Apolipoprotein E inhibits the depolymerization of beta 2-microglobulin-related amyloid fibrils at a neutral pH
Biochemistry
2001
40: 8499-8507
|
| 19661459 |
Yao Y et al.:
Heat shock protein 70 enhances vascular bone morphogenetic protein-4 signaling by binding matrix Gla protein
Circ. Res.
2009
105: 575-584
|
| 22698853 |
Xu H et al.:
The function of BMP4 during neurogenesis in the adult hippocampus in Alzheimers disease
Ageing Res. Rev.
2013
12: 157-164
|
| 19941948 |
Bonomini F et al.:
Apolipoprotein E and its role in aging and survival
Exp. Gerontol.
2010
45: 149-157
|
| 28877212 |
Yao H et al.:
Selenium deficiency-induced alterations in ion profiles in chicken muscle
PLoS ONE
2017
12
|
| 27473727 |
Schweizer U et al.:
Why 21? The significance of selenoproteins for human health revealed by inborn errors of metabolism
FASEB J.
2016
30: 3669-3681
|
| 27355821 |
Pallister T et al.:
Characterizing Blood Metabolomics Profiles Associated with Self-Reported Food Intakes in Female Twins
PLoS ONE
2016
11
|
| 22823870 |
Ang JE et al.:
Identification of human plasma metabolites exhibiting time-of-day variation using an untargeted liquid chromatography-mass spectrometry metabolomic approach
Chronobiol. Int.
2012
29: 868-881
|
| 23946426 |
Chua EC et al.:
Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans
Proc. Natl. Acad. Sci. U.S.A.
2013
110
|
| 28892773 |
Sharma VK et al.:
Assessment of toxicity of selenium and cadmium selenium quantum dots: A review
Chemosphere
2017
188: 403-413
|
| 28042811 |
Schomburg L et al.:
Dietary Selenium and Human Health
|
| 25012761 |
Mickiewicz B et al.:
Metabolic changes associated with selenium deficiency in mice
Biometals
2014
27: 1137-1147
|
| 23500078 |
Tsujimoto S et al.:
Selenium-binding protein 1: its physiological function, dependence on aryl hydrocarbon receptors, and role in wasting syndrome by 2,3,7,8-tetrachlorodibenzo-p-dioxin
Biochim. Biophys. Acta
2013
1830: 3616-3624
|
| 23243309 |
Fujita M et al.:
Insulin-like growth factor (IGF) signaling requires alphavbeta3-IGF1-IGF type 1 receptor (IGF1R) ternary complex formation in anchorage independence, and the complex formation does not require IGF1R and Src activation
J. Biol. Chem.
2013
288: 3059-3069
|
| 17331073 |
Hornemann T et al.:
Is the mammalian serine palmitoyltransferase a high-molecular-mass complex? }, authors { names std { { name ml Hornemann T, affil str Institute for Clinical Chemistry, University Hospital Zurich, Ramistrasse 100, CH-8091 Zurich, Switzerland. thorsten.hornemann@usz.ch }, { name ml Wei Y }, { name ml von Eckardstein A } } }, from journal { title { iso-jta Biochem. J
Biochem. J.
2007
405: 157-164
|
| 19416851 |
Han G et al.:
Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 8186-8191
|
| 25452428 |
Marino M et al.:
SEPN1, an endoplasmic reticulum-localized selenoprotein linked to skeletal muscle pathology, counteracts hyperoxidation by means of redox-regulating SERCA2 pump activity
Hum. Mol. Genet.
2015
24: 1843-1855
|
| 24819087 |
Liu CP et al.:
Effects of dietary selenium deficiency on mRNA levels of twenty-one selenoprotein genes in the liver of layer chicken
Biol Trace Elem Res
2014
159: 192-198
|
| 22536434 |
Li JL et al.:
Priority in selenium homeostasis involves regulation of SepSecS transcription in the chicken brain
PLoS ONE
2012
7
|
| 21613214 |
Ye R et al.:
Biochemical analysis of the canonical model for the mammalian circadian clock
J. Biol. Chem.
2011
286
|
| 22334666 |
Feng C et al.:
Kindlin-3 mediates integrin alphaLbeta2 outside-in signaling, and it interacts with scaffold protein receptor for activated-C kinase 1 (RACK1)
J. Biol. Chem.
2012
287
|
| 9442085 |
Liliental J et al.:
Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit
J. Biol. Chem.
1998
273: 2379-2383
|
| 9267036 |
Chen H et al.:
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300
Cell
1997
90: 569-580
|
| 11741546 |
Chen XB et al.:
Human Mus81-associated endonuclease cleaves Holliday junctions in vitro
Mol. Cell
2001
8: 1117-1127
|
| 12628926 |
Yoon HG et al.:
Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1
EMBO J.
2003
22: 1336-1346
|
| 15454082 |
Fujita N et al.:
MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation
Cell
2004
119: 75-86
|
| 9323142 |
Horiuchi H et al.:
A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function
Cell
1997
90: 1149-1159
|
| 22351760 |
Fujita M et al.:
Cross-talk between integrin alpha6beta4 and insulin-like growth factor-1 receptor (IGF1R) through direct alpha6beta4 binding to IGF1 and subsequent alpha6beta4-IGF1-IGF1R ternary complex formation in anchorage-independent conditions
J. Biol. Chem.
2012
287
|
| 9150135 |
Zhang Y et al.:
Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex
Cell
1997
89: 357-364
|
| 8710870 |
Fondell JD et al.:
Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex
Proc. Natl. Acad. Sci. U.S.A.
1996
93: 8329-8333
|
| 22065579 |
Gibbs PE et al.:
Formation of ternary complex of human biliverdin reductase-protein kinase Cdelta-ERK2 protein is essential for ERK2-mediated activation of Elk1 protein, nuclear factor-kappaB, and inducible nitric-oxidase synthase (iNOS)
J. Biol. Chem.
2012
287: 1066-1079
|
| 22528496 |
Kim JK et al.:
PDZ domain-containing 1 (PDZK1) protein regulates phospholipase C-beta3 (PLC-beta3)-specific activation of somatostatin by forming a ternary complex with PLC-beta3 and somatostatin receptors
J. Biol. Chem.
2012
287
|
| 26714931 |
Wrobel JK et al.:
Biological activity of selenium: Revisited
IUBMB Life
2016
68: 97-105
|
| 12807419 |
Chen J et al.:
Selenium and selenoproteins in the brain and brain diseases
J. Neurochem.
2003
86: 1-12
|
| 24987004 |
Labunskyy VM et al.:
Selenoproteins: molecular pathways and physiological roles
Physiol. Rev.
2014
94: 739-777
|
| 21854986 |
Thomas C et al.:
Structural linkage between ligand discrimination and receptor activation by type I interferons
Cell
2011
146: 621-632
|
| 24185753 |
Roman M et al.:
Selenium biochemistry and its role for human health
Metallomics
2014
6: 25-54
|
| 17889651 |
Jin MS et al.:
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
Cell
2007
130: 1071-1082
|
| 14505576 |
Yuan JP et al.:
Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors
Cell
2003
114: 777-789
|
| 24760755 |
Burk RF et al.:
Selenoprotein P and apolipoprotein E receptor-2 interact at the blood-brain barrier and also within the brain to maintain an essential selenium pool that protects against neurodegeneration
FASEB J.
2014
28: 3579-3588
|
| 24174529 |
Mascle XH et al.:
Identification of a non-covalent ternary complex formed by PIAS1, SUMO1, and UBC9 proteins involved in transcriptional regulation
J. Biol. Chem.
2013
51
|
| 22679021 |
Sato Y et al.:
Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13
J. Biol. Chem.
2012
31
|
| 5656824 |
et al.:
Propionylcarnitine. Physiological variations in vivo
Biochim. Biophys. Acta
1968
152: 559-567
|
| 5441209 |
author information missing
The conversion of valine to propionylcarnitine in isolated rat liver mitochondria
Biochim. Biophys. Acta
1970
208: 167-169
|
| 28440906 |
van den Berg R et al.:
Familial longevity is characterized by high circadian rhythmicity of serum cholesterol in healthy elderly individuals
Aging Cell
2017
16: 237-243
|
| 23543136 |
Menni C et al.:
Targeted metabolomics profiles are strongly correlated with nutritional patterns in women
Metabolomics
2013
9: 506-514
|
| 24760973 |
Scalbert A et al.:
The food metabolome: a window over dietary exposure
Am. J. Clin. Nutr.
2014
99: 1286-1308
|
| 20725044 |
Huang CS et al.:
Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase
Nature
2010
466: 1001-1005
|
| 23814056 |
Gingras AR et al.:
The structure of the ternary complex of Krev interaction trapped 1 (KRIT1) bound to both the Rap1 GTPase and the heart of glass (HEG1) cytoplasmic tail
J. Biol. Chem.
2013
288
|
| 22381456 |
Rayman MP et al.:
Selenium and human health
Lancet
2012
379: 1256-1268
|
| 20007487 |
Glading AJ et al.:
Rap1 and its effector KRIT1/CCM1 regulate beta-catenin signaling
Dis Model Mech
2010
3: 73-83
|
| 14651849 |
Inoki K et al.:
TSC2 mediates cellular energy response to control cell growth and survival
Cell
2003
115: 577-590
|
| 9094723 |
Hay JC et al.:
Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells
Cell
1997
89: 149-158
|
| 29148426 |
Rodriguez Camargo DC et al.:
Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate
|
| 27193190 |
Sullivan PM et al.:
The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway
Acta Neuropathol Commun
2016
4: 51
|
| 11085976 |
Shiraishi A et al.:
A novel glucokinase regulator in pancreatic beta cells: precursor of propionyl-CoA carboxylase beta subunit interacts with glucokinase and augments its activity
J. Biol. Chem.
2001
276: 2325-2328
|
| 22927646 |
Lucki NC et al.:
Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor
Mol. Cell. Biol.
2012
32: 4419-4431
|
| 29290465 |
Ingold I et al.:
Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis
|
| 7668348 |
Tyynela J et al.:
Sphingolipid activator proteins (SAPs) are stored together with glycosphingolipids in the infantile neuronal ceroid-lipofuscinosis (INCL)
Am. J. Med. Genet.
1995
57: 294-297
|
| 25402683 |
Friedmann Angeli JP et al.:
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Nat. Cell Biol.
2014
16: 1180-1191
|
| 29311617 |
Larraufie P et al.:
SCFAs strongly stimulate PYY production in human enteroendocrine cells
Sci Rep
2018
8: 74
|
| 27842070 |
Doll S et al.:
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
Nat. Chem. Biol.
2017
13: 91-98
|
| 24390407 |
Andersen MB et al.:
Discovery and validation of urinary exposure markers for different plant foods by untargeted metabolomics
Anal Bioanal Chem
2014
406: 1829-1844
|
| 21865330 |
Lloyd AJ et al.:
Use of mass spectrometry fingerprinting to identify urinary metabolites after consumption of specific foods
Am. J. Clin. Nutr.
2011
94: 981-991
|
| 24740205 |
Guertin KA et al.:
Metabolomics in nutritional epidemiology: identifying metabolites associated with diet and quantifying their potential to uncover diet-disease relations in populations
Am. J. Clin. Nutr.
2014
100: 208-217
|
| 24882253 |
Garcia-Aloy M et al.:
Novel multimetabolite prediction of walnut consumption by a urinary biomarker model in a free-living population: the PREDIMED study
J. Proteome Res.
2014
13: 3476-3483
|
| 29315709 |
Falhammar H et al.:
Successful fertility outcome in a woman with 17a-hydroxylase deficiency
|
| 23527880 |
Alexandre-Gouabau MC et al.:
Maternal and cord blood LC-HRMS metabolomics reveal alterations in energy and polyamine metabolism, and oxidative stress in very-low birth weight infants
J. Proteome Res.
2013
12: 2764-2778
|
| 11451951 |
Ferlinz K et al.:
Human acid ceramidase: processing, glycosylation, and lysosomal targeting
J. Biol. Chem.
2001
276
|
| 15095475 |
Bohne S et al.:
Cleavage of AL amyloid proteins and AL amyloid deposits by cathepsins B, K, and L
J. Pathol.
2004
203: 528-537
|
| 16186510 |
Ye Y et al.:
Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane
Proc. Natl. Acad. Sci. U.S.A.
2005
102
|
| 10092105 |
Godar S et al.:
M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-beta1
Eur. J. Immunol.
1999
29: 1004-1013
|
| 29352114 |
Rehage N et al.:
Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA
Nat Commun
2018
9: 299
|
| 18443601 |
Urayama A et al.:
Mannose 6-phosphate receptor-mediated transport of sulfamidase across the blood-brain barrier in the newborn mouse
Mol. Ther.
2008
16: 1261-1266
|
| 7961735 |
McMaster CR et al.:
Phosphatidylcholine biosynthesis in Saccharomyces cerevisiae. Regulatory insights from studies employing null and chimeric sn-1,2-diacylglycerol choline- and ethanolaminephosphotransferases
J. Biol. Chem.
1994
269
|
| 26315306 |
Huang JQ et al.:
Characterization of Selenoprotein M and Its Response to Selenium Deficiency in Chicken Brain
Biol Trace Elem Res
2016
170: 449-458
|
| 12697764 |
Nair P et al.:
Characterization of the endosomal sorting signal of the cation-dependent mannose 6-phosphate receptor
J. Biol. Chem.
2003
278
|
| 26398431 |
Solovyev ND et al.:
Importance of selenium and selenoprotein for brain function: From antioxidant protection to neuronal signalling
J. Inorg. Biochem.
2015
153: 1-12
|
| 10446223 |
Han DC et al.:
Association of focal adhesion kinase with Grb7 and its role in cell migration
J. Biol. Chem.
1999
274
|
| 18273060 |
Tsai NP et al.:
Regulation of stress granule dynamics by Grb7 and FAK signalling pathway
EMBO J.
2008
27: 715-726
|
| 9186920 |
Plump AS et al.:
ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotes
J. Lipid Res.
1997
38: 1033-1047
|
| 8647961 |
Plump AS et al.:
Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production
J. Clin. Invest.
1996
97: 2660-2671
|
| 28848044 |
Srivastava S et al.:
Regulation of mitochondrial protein import by the nucleotide exchange factors GrpEL1 and GrpEL2 in human cells
J. Biol. Chem.
2017
292
|
| 27484798 |
Dema A et al.:
The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase 3beta Interaction Protein (GSKIP) Regulates beta-Catenin through Its Interactions with Both Protein Kinase A (PKA) and GSK3beta
J. Biol. Chem.
2016
291
|
| 16788211 |
Iwamoto N et al.:
ABCA7 expression is regulated by cellular cholesterol through the SREBP2 pathway and associated with phagocytosis
J. Lipid Res.
2006
47: 1915-1927
|
| 9422368 |
Suresh S et al.:
Cellular cholesterol storage in the Niemann-Pick disease type C mouse is associated with increased expression and defective processing of apolipoprotein D
J. Neurochem.
1998
70: 242-251
|
| 20007971 |
Hundsrucker C et al.:
Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein
J. Biol. Chem.
2010
285: 5507-5521
|
| 25920809 |
Loh JK et al.:
GSKIP- and GSK3-mediated anchoring strengthens cAMP/PKA/Drp1 axis signaling in the regulation of mitochondrial elongation
Biochim. Biophys. Acta
2015
1853: 1796-1807
|
| 22016385 |
Shchedrina VA et al.:
Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic reticulum homeostasis
J. Biol. Chem.
2011
286
|
| 22155432 |
Fredericks GJ et al.:
Selenoprotein K Increases Efficiency of DHHC6 Catalyzed Protein Palmitoylation by Stabilizing the Acyl-DHHC6 Intermediate
|
| 25368151 |
Fredericks GJ et al.:
Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex
Proc. Natl. Acad. Sci. U.S.A.
2014
111
|
| 20018346 |
Sanchez C et al.:
Plasma levels of copper, manganese and selenium in an adult population in southern Spain: influence of age, obesity and lifestyle factors
Sci. Total Environ.
2010
408: 1014-1020
|
| 9819414 |
Haft CR et al.:
Identification of a family of sorting nexin molecules and characterization of their association with receptors
Mol. Cell. Biol.
1998
18: 7278-7287
|
| 15972957 |
Mak BC et al.:
Aberrant beta-catenin signaling in tuberous sclerosis
Am. J. Pathol.
2005
167: 107-116
|
| 9353307 |
Eggert M et al.:
The glucocorticoid receptor is associated with the RNA-binding nuclear matrix protein hnRNP U
J. Biol. Chem.
1997
272
|
| 10716937 |
Kong M et al.:
Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction
EMBO J.
2000
19: 1378-1388
|
| 11489896 |
Rothbauer U et al.:
Role of the deafness dystonia peptide 1 (DDP1) in import of human Tim23 into the inner membrane of mitochondria
J. Biol. Chem.
2001
276
|
| 14820832 |
author information missing
The aromatization of hydrogenated derivatives of benzoic acid in animal tissues
Biochem. J.
1951
48: 222-237
|
| 18318670 |
Toromanovic J et al.:
Urinary hippuric acid after ingestion of edible fruits
Bosn J Basic Med Sci
2008
8: 38-43
|
| 8482596 |
Inoue O et al.:
Excretion of methylhippuric acids in urine of workers exposed to a xylene mixture: comparison among three xylene isomers and toluene
Int Arch Occup Environ Health
1993
64: 533-539
|
| 28337503 |
Behr C et al.:
Gut microbiome-related metabolic changes in plasma of antibiotic-treated rats
Arch. Toxicol.
2017
91: 3439-3454
|
| 23342949 |
Lees HJ et al.:
Hippurate: the natural history of a mammalian-microbial cometabolite
J. Proteome Res.
2013
12: 1527-1546
|
| 9458768 |
Yoshimura T et al.:
Hepatic uptake of hippurate: a multiple-indicator dilution, perfused rat liver study
Am. J. Physiol.
1998
274: G10-G20
|
| 637841 |
author information missing
The metabolism of shikimate in the rat
Biochem. J.
1978
170: 257-264
|
| 12771321 |
Olthof MR et al.:
Chlorogenic acid, quercetin-3-rutinoside and black tea phenols are extensively metabolized in humans
J. Nutr.
2003
133: 1806-1814
|
| 17428148 |
Knights KM et al.:
Amino acid conjugation: contribution to the metabolism and toxicity of xenobiotic carboxylic acids
Expert Opin Drug Metab Toxicol
2007
3: 159-168
|
| 25497115 |
Lennerz BS et al.:
Effects of sodium benzoate, a widely used food preservative, on glucose homeostasis and metabolic profiles in humans
Mol. Genet. Metab.
2015
114: 73-79
|
| 17467679 |
Buhaescu I et al.:
Mevalonate pathway: a review of clinical and therapeutical implications
Clin. Biochem.
2007
40: 575-584
|
| 26777690 |
Wei W et al.:
Ligand Activation of ERRalpha by Cholesterol Mediates Statin and Bisphosphonate Effects
Cell Metab.
2016
23: 479-491
|
| 7071414 |
author information missing
Phenylalanine ammonia lyase in the management of phenylketonuria: the relationship between ingested cinnamate and urinary hippurate in humans
Res. Commun. Chem. Pathol. Pharmacol.
1982
35: 275-282
|
| 8812443 |
Masuno M et al.:
Assignment of the human cytosolic acetoacetyl-coenzyme A thiolase (ACAT2) gene to chromosome 6q25.3-q26
Genomics
1996
36: 217-218
|
| 9380443 |
Fukao T et al.:
Enzymes of ketone body utilization in human tissues: protein and messenger RNA levels of succinyl-coenzyme A (CoA):3-ketoacid CoA transferase and mitochondrial and cytosolic acetoacetyl-CoA thiolases
Pediatr. Res.
1997
42: 498-502
|
| 17077281 |
Shibata N et al.:
Regulation of hepatic cholesterol synthesis by a novel protein (SPF) that accelerates cholesterol biosynthesis
FASEB J.
2006
20: 2642-2644
|
| 26114596 |
Mitsche MA et al.:
Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways
Elife
2015
4
|
| 25637936 |
Luu W et al.:
The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally
J. Lipid Res.
2015
56: 888-897
|
| 16989930 |
Trosken ER et al.:
Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles
Toxicology
2006
228: 24-32
|
| 29325019 |
Zaghlool SB et al.:
Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation
Hum. Mol. Genet.
2018
27: 1106-1121
|
| 19144698 |
Berrocal M et al.:
Altered Ca2+ dependence of synaptosomal plasma membrane Ca2+-ATPase in human brain affected by Alzheimers disease
FASEB J.
2009
23: 1826-1834
|
| 29653253 |
Wang Y et al.:
Cholesterol and bile acid-mediated regulation of autophagy in fatty liver diseases and atherosclerosis
Biochim. Biophys. Acta
2018
1863: 726-733
|
| 20210363 |
Johnson BJ et al.:
Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8
Biochemistry
2010
49: 3403-3411
|
| 29227833 |
Tian Y et al.:
Vitamin A deficiency in mice alters host and gut microbial metabolism leading to altered energy homeostasis
J. Nutr. Biochem.
2018
54: 28-34
|
| 28753012 |
Munger LH et al.:
Identification of Urinary Food Intake Biomarkers for Milk, Cheese, and Soy-Based Drink by Untargeted GC-MS and NMR in Healthy Humans
J. Proteome Res.
2017
16: 3321-3335
|
| 17627937 |
Lin BC et al.:
Liver-specific activities of FGF19 require Klotho beta
J. Biol. Chem.
2007
282
|
| 29749694 |
Li D et al.:
Trimethylamine-N-oxide promotes brain aging and cognitive impairment in mice
|
| 28070145 |
Kushiyama A et al.:
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis
Mediators Inflamm.
2016
2016
|
| 16324927 |
Kaya M et al.:
Plasma concentrations and urinary excretion of purine bases (uric acid, hypoxanthine, and xanthine) and oxypurinol after rigorous exercise
Metab. Clin. Exp.
2006
55: 103-107
|
| 18074171 |
Mittal A et al.:
The potential role for xanthine oxidase inhibition in major intra-abdominal surgery
World J Surg
2008
32: 288-295
|
| 3294898 |
author information missing
Conversion of xanthine dehydrogenase to oxidase in ischemic rat tissues
J. Clin. Invest.
1987
79: 1564-1570
|
| 8157711 |
Bagatell CJ et al.:
Physiological levels of estradiol stimulate plasma high density lipoprotein2 cholesterol levels in normal men
J. Clin. Endocrinol. Metab.
1994
78: 855-861
|
| 1586105 |
Bagatell CJ et al.:
Physiologic testosterone levels in normal men suppress high-density lipoprotein cholesterol levels
Ann. Intern. Med.
1992
116: 967-973
|
| 28396346 |
Budelier MM et al.:
Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1
J. Biol. Chem.
2017
292: 9294-9304
|
| 18191748 |
Gomez-Cabrera MC et al.:
Moderate exercise is an antioxidant: upregulation of antioxidant genes by training
Free Radic. Biol. Med.
2008
44: 126-131
|
| 29307522 |
Riberio DF et al.:
Acute exercise alters homocysteine plasma concentration in an intensity-dependent manner due increased methyl flux in liver of rats
Life Sci.
2018
196: 63-68
|
| 6822065 |
author information missing
Purine transport and metabolism in man: the effect of exercise on concentrations of purine bases, nucleosides and nucleotides in plasma, urine, leucocytes and erythrocytes
Clin. Sci.
1983
64: 333-340
|
| 7395984 |
author information missing
AMP deamination and IMP reamination in working skeletal muscle
Am. J. Physiol.
1980
239: C32-C38
|
| 17347008 |
Li X et al.:
Comparative molecular characterization of ADSS1 and ADSS2 genes in pig (Sus scrofa)
Comp. Biochem. Physiol. B
2007
147: 271-277
|
| 20716488 |
Fernandez JR et al.:
Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine
Bioorg. Med. Chem.
2010
18: 6748-6755
|
| 8128888 |
Hellsten-Westing Y et al.:
The effect of high-intensity training on purine metabolism in man
Acta Physiol. Scand.
1993
149: 405-412
|
| 29095874 |
Rannou F et al.:
Effects of AMPD1 common mutation on the metabolic-chronotropic relationship: Insights from patients with myoadenylate deaminase deficiency
PLoS ONE
2017
12
|
| 8945937 |
Darvish A et al.:
Contribution of cytosolic and membrane-bound 5-nucleotidases to cardiac adenosine production
Am. J. Physiol.
1996
271
|
| 3966542 |
author information missing
Influence of acidosis on AMP deaminase activity in contracting fast-twitch muscle
Am. J. Physiol.
1985
248: C43-C50
|
| 28432611 |
Dudzinska W et al.:
Comparison of human erythrocyte purine nucleotide metabolism and blood purine and pyrimidine degradation product concentrations before and after acute exercise in trained and sedentary subjects
J Physiol Sci
2018
68: 293-305
|
| 19219384 |
McCrossan ZA et al.:
Regulation of the Kv2.1 potassium channel by MinK and MiRP1
J. Membr. Biol.
2009
228: 1-14
|
| 26311497 |
Xu D et al.:
PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus
Nat Commun
2015
6: 8100
|
| 28740157 |
Shibata N et al.:
Regulation of hepatic cholesterol synthesis by a novel protein (SPF) that accelerates cholesterol biosynthesis
FASEB J.
2006
20: 2642-2644
|
| 11118147 |
de Urquiza AM et al.:
Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain
Science
2000
290: 2140-2144
|
| 10545153 |
Hellsten Y et al.:
AMP deamination and purine exchange in human skeletal muscle during and after intense exercise
J. Physiol. (Lond.)
1999
520: Pt 3 909-920
|
| 2058662 |
Spencer MK et al.:
Role of glycogen in control of glycolysis and IMP formation in human muscle during exercise
Am. J. Physiol.
1991
260: E859-E864
|
| 11344228 |
Fukui H et al.:
Enhanced activity of the purine nucleotide cycle of the exercising muscle in patients with hyperthyroidism
J. Clin. Endocrinol. Metab.
2001
86: 2205-2210
|
| 8928734 |
Tullson PC et al.:
IMP reamination to AMP in rat skeletal muscle fiber types
Am. J. Physiol.
1996
270
|
| 25355190 |
Sahlin K et al.:
Muscle energetics during explosive activities and potential effects of nutrition and training
Sports Med
2014
44: Suppl 2 S167-S173
|
| 2261897 |
Yamamoto T et al.:
The effect of completely purine-free diet of low sodium content on purine intermediates and end-product
Eur J Clin Nutr
1990
44: 659-664
|
| 16556865 |
Shamgar L et al.:
Calmodulin is essential for cardiac IKS channel gating and assembly: impaired function in long-QT mutations
Circ. Res.
2006
98: 1055-1063
|
| 15308499 |
Robergs RA et al.:
Biochemistry of exercise-induced metabolic acidosis
Am. J. Physiol. Regul. Integr. Comp. Physiol.
2004
287: R502-R516
|
| 27840611 |
de Araujo GG et al.:
Short and Long Term Effects of High-Intensity Interval Training on Hormones, Metabolites, Antioxidant System, Glycogen Concentration, and Aerobic Performance Adaptations in Rats
Front Physiol
2016
7: 505
|
| 22694348 |
Breitbach S et al.:
Circulating cell-free DNA: an up-coming molecular marker in exercise physiology
Sports Med
2012
42: 565-586
|
| 28192465 |
Suarez-Garcia S et al.:
Impact of a cafeteria diet and daily physical training on the rat serum metabolome
PLoS ONE
2017
12
|
| 21364483 |
Zielinski J et al.:
Effect of training load structure on purine metabolism in middle-distance runners
Med Sci Sports Exerc
2011
43: 1798-1807
|
| 10502075 |
Sahlin K et al.:
Plasma hypoxanthine and ammonia in humans during prolonged exercise
Eur J Appl Physiol Occup Physiol
1999
80: 417-422
|
| 2361781 |
Sahlin K et al.:
Adenine nucleotide depletion in human muscle during exercise: causality and significance of AMP deamination
Int J Sports Med
1990
11: Suppl 2 S62-S67
|
| 29031089 |
Shults CL et al.:
17beta-estradiol regulates the RNA-binding protein Nova1, which then regulates the alternative splicing of estrogen receptor beta in the aging female rat brain
Neurobiol. Aging
2018
61: 13-22
|
| 27677364 |
Tang FC et al.:
Contribution of branched-chain amino acids to purine nucleotide cycle: a pilot study
Eur J Clin Nutr
2017
71: 587-593
|
| 21638570 |
Arinze IJ et al.:
Facilitating understanding of the purine nucleotide cycle and the one-carbon pool: Part I: The purine nucleotide cycle
Biochem Mol Biol Educ
2005
33: 165-168
|
| 22688987 |
Zhao L et al.:
Proteomic investigation of changes in rat skeletal muscle after exercise-induced fatigue
Biol. Res.
2012
45: 75-80
|
| 20714766 |
Dudzinska W et al.:
Adenine, guanine and pyridine nucleotides in blood during physical exercise and restitution in healthy subjects
Eur. J. Appl. Physiol.
2010
110: 1155-1162
|
| 29363833 |
Alonso-Andres P et al.:
Purine-related metabolites and their converting enzymes are altered in frontal, parietal and temporal cortex at early stages of Alzheimers disease pathology
|
| 26295370 |
Shults CL et al.:
Aging and Loss of Circulating 17beta-Estradiol Alters the Alternative Splicing of ERbeta in the Female Rat Brain
Endocrinology
2015
156: 4187-4199
|
| 8045862 |
Stathis CG et al.:
Influence of sprint training on human skeletal muscle purine nucleotide metabolism
J. Appl. Physiol.
1994
76: 1802-1809
|
| 29126187 |
Wang X et al.:
Med12 regulates ovarian steroidogenesis, uterine development and maternal effects in the mammalian egg
Biol. Reprod.
2017
97: 822-834
|
| 11821531 |
Westerblad H et al.:
Muscle fatigue: lactic acid or inorganic phosphate the major cause?
News Physiol. Sci.
2002
17: 17-21
|
| 20888124 |
Xu J et al.:
Increased sensitivity of group III and group IV afferents from incised muscle in vitro
Pain
2010
151: 744-755
|
| 29867560 |
Vereshchaka IV et al.:
C60 Fullerenes Diminish Muscle Fatigue in Rats Comparable to N-acetylcysteine or beta-Alanine
Front Physiol
2018
9: 517
|
| 29966293 |
Huang WC et al.:
The Effects of Thiamine Tetrahydrofurfuryl Disulfide on Physiological Adaption and Exercise Performance Improvement
|
| 28433923 |
Liu H et al.:
UHPLC-Q-Orbitrap-HRMS-based global metabolomics reveal metabolome modifications in plasma of young women after cranberry juice consumption
J. Nutr. Biochem.
2017
45: 67-76
|
| 29186400 |
Murphy RA et al.:
Metabolites associated with risk of developing mobility disability in the Health, Aging and Body Composition Study
|
| 22526472 |
Deng H et al.:
Aspirin metabolites are GPR35 agonists
Naunyn Schmiedebergs Arch. Pharmacol.
2012
385: 729-737
|
| 29700012 |
Serna VA et al.:
Cellular kinetics of MED12-mutant uterine leiomyoma growth and regression in vivo
Endocr. Relat. Cancer
2018
25: 747-759
|
| 28110955 |
Beringer A et al.:
Determination of inosine 5-monophosphate dehydrogenase activity in red blood cells of thiopurine-treated patients using HPLC
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
2017
1044-1045: 194-199
|
| 11867769 |
Kang YK et al.:
The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro
Proc. Natl. Acad. Sci. U.S.A.
2002
99: 2642-2647
|
| 16267323 |
Haberle J et al.:
Congenital glutamine deficiency with glutamine synthetase mutations
N. Engl. J. Med.
2005
353: 1926-1933
|
| 22132970 |
Filoni DN et al.:
Initial studies to define the physiologic role of cN-II
Nucleosides Nucleotides Nucleic Acids
2011
30: 1155-1160
|
| 18404470 |
Ipata PL et al.:
Recent advances in structure and function of cytosolic IMP-GMP specific 5-nucleotidase II (cN-II)
Purinergic Signal.
2006
2: 669-675
|
| 19047373 |
Knuesel MT et al.:
The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator
Mol. Cell. Biol.
2009
29: 650-661
|
| 11875118 |
Richards JS et al.:
Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins
Mol. Endocrinol.
2002
16: 580-599
|
| 27895094 |
Kumar S et al.:
Crosstalk between microRNA-122 and FOX family genes in HepG2 cells
Exp. Biol. Med. (Maywood)
2017
242: 436-440
|
| 11353774 |
Zhao HH et al. et al.:
Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions
J. Biol. Chem.
2001
276
|
| 29983231 |
Zhu D et al.:
Extragonadal Effects of Follicle-Stimulating Hormone on Osteoporosis and Cardiovascular Disease in Women during Menopausal Transition
Trends Endocrinol. Metab.
2018
29: 571-580
|
| 29907245 |
Cheung CL et al.:
Serum follicle stimulating hormone is associated with reduced risk of diabetes in postmenopausal women: The Hong Kong osteoporosis study
Maturitas
2018
114: 41-45
|
| 18162510 |
Nakae J et al.:
Forkhead transcription factor FoxO1 in adipose tissue regulates energy storage and expenditure
Diabetes
2008
57: 563-576
|
| 19896444 |
Paik JH et al. et al.:
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis
Cell Stem Cell
2009
5: 540-553
|
| 8380692 |
Iwahana H et al.:
Molecular cloning of human amidophosphoribosyltransferase
Biochem. Biophys. Res. Commun.
1993
190: 192-200
|
| 20631005 |
Welin M et al.:
Structural studies of tri-functional human GART
Nucleic Acids Res.
2010
38: 7308-7319
|
| 28029518 |
Pedley AM et al.:
A New View into the Regulation of Purine Metabolism: The Purinosome
Trends Biochem. Sci.
2017
42: 141-154
|
| 22653058 |
Kim KW et al.:
FOXO1 in the ventromedial hypothalamus regulates energy balance
J. Clin. Invest.
2012
122: 2578-2589
|
| 15902552 |
Zikanova M et al.:
Preparation of 5-amino-4-imidazole-N-succinocarboxamide ribotide, 5-amino-4-imidazole-N-succinocarboxamide riboside and succinyladenosine, compounds usable in diagnosis and research of adenylosuccinate lyase deficiency
J. Inherit. Metab. Dis.
2005
28: 493-499
|
| 22186407 |
Kim HJ et al.:
Overexpression of FoxO1 in the hypothalamus and pancreas causes obesity and glucose intolerance
Endocrinology
2012
153: 659-671
|
| 19196834 |
Liu Z et al.:
FSH and FOXO1 regulate genes in the sterol/steroid and lipid biosynthetic pathways in granulosa cells
Mol. Endocrinol.
2009
23: 649-661
|
| 21937711 |
Buchman JJ et al.:
ASPM regulates Wnt signaling pathway activity in the developing brain
Genes Dev.
2011
25: 1909-1914
|
| 27940300 |
Menon B et al.:
Molecular regulation of LHCGR expression by miR-122 during follicle growth in the rat ovary
Mol. Cell. Endocrinol.
2017
442: 81-89
|
| 22913342 |
Prenzel T et al.:
Cohesin is required for expression of the estrogen receptor-alpha (ESR1) gene
Epigenetics Chromatin
2012
5: 13
|
| 26460619 |
Rao YS et al.:
Prolonged ovarian hormone deprivation alters the effects of 17beta-estradiol on microRNA expression in the aged female rat hypothalamus
Oncotarget
2015
6
|
| 28633944 |
de Luis DA et al.:
Gene expression analysis identify a metabolic and cell function alterations as a hallmark of obesity without metabolic syndrome in peripheral blood, a pilot study
Clin Nutr
2018
37: 1348-1353
|
| 29248466 |
Cao Q et al.:
Leptin suppresses microRNA-122 promoter activity by phosphorylation of foxO1 in hepatic stellate cell contributing to leptin promotion of mouse liver fibrosis
Toxicol. Appl. Pharmacol.
2018
339: 143-150
|
| 27939741 |
Holzer K et al. et al.:
Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer
Am. J. Pathol.
2017
187: 228-235
|
| 8636360 |
Reame NE et al.:
Age effects of follicle-stimulating hormone and pulsatile luteinizing hormone secretion across the menstrual cycle of premenopausal women
J. Clin. Endocrinol. Metab.
1996
81: 1512-1518
|
| 16441918 |
Lin WT et al.:
L-Arginine attenuates xanthine oxidase and myeloperoxidase activities in hearts of rats during exhaustive exercise
Br. J. Nutr.
2006
95: 67-75
|
| 18757399 |
Durchdewald M et al.:
Podoplanin is a novel fos target gene in skin carcinogenesis
Cancer Res.
2008
68: 6877-6883
|
| 30096135 |
Dyar KA et al. et al.:
Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock
PLoS Biol.
2018
16
|
| 29296106 |
Seifert JG et al.:
The influence of D-ribose ingestion and fitness level on performance and recovery
J Int Soc Sports Nutr
2017
14: 47
|
| 17709396 |
Scibetta AG et al.:
Functional analysis of the transcription repressor PLU-1/JARID1B
Mol. Cell. Biol.
2007
27: 7220-7235
|
| 29074724 |
Qian X et al.:
Conversion of PRPS Hexamer to Monomer by AMPK-Mediated Phosphorylation Inhibits Nucleotide Synthesis in Response to Energy Stress
Cancer Discov
2018
8: 94-107
|
| 1529104 |
Van den Berghe G et al.:
The purine nucleotide cycle and its molecular defects
Prog. Neurobiol.
1992
39: 547-561
|
| 14517211 |
Bronder JL et al.:
A defect in the p53 response pathway induced by de novo purine synthesis inhibition
J. Biol. Chem.
2003
278
|
| 15611036 |
Nybo L et al.:
Cerebral ammonia uptake and accumulation during prolonged exercise in humans
J. Physiol. (Lond.)
2005
563: 285-290
|
| 23846817 |
Rice S et al.:
Metformin inhibits follicle-stimulating hormone (FSH) action in human granulosa cells: relevance to polycystic ovary syndrome
J. Clin. Endocrinol. Metab.
2013
98
|
| 28844079 |
Thottam GE et al.:
Gout and Metabolic Syndrome: a Tangled Web
Curr Rheumatol Rep
2017
19: 60
|
| 25459662 |
author information missing
Effects of pharmacological AMP deaminase inhibition and Ampd1 deletion on nucleotide levels and AMPK activation in contracting skeletal muscle
Chem. Biol.
2014
21: 1497-1510
|
| 29115382 |
Feng YL et al.:
Resveratrol prevents osteoporosis by upregulating FoxO1 transcriptional activity
Int. J. Mol. Med.
2018
41: 202-212
|
| 27327080 |
Gudiksen A et al.:
Lack of Skeletal Muscle IL-6 Affects Pyruvate Dehydrogenase Activity at Rest and during Prolonged Exercise
PLoS ONE
2016
11
|
| 27128383 |
Schmitt DL et al.:
Sequestration-Mediated Downregulation of de Novo Purine Biosynthesis by AMPK
ACS Chem. Biol.
2016
11: 1917-1924
|
| 30040013 |
Zaleski AL et al.:
The Influence of Compression Socks During a Marathon on Exercise-Associated Muscle Damage
|
| 29101234 |
Kanemitsu T et al.:
Periodic variation in bile acids controls circadian changes in uric acid via regulation of xanthine oxidase by the orphan nuclear receptor PPARalpha
J. Biol. Chem.
2017
292
|
| 17549627 |
Galoyan AA et al.:
Effect of hypothalamic proline-rich peptide (PRP-1) on neuronal and bone marrow cell apoptosis
Neurochem. Res.
2007
32: 1898-1905
|
| 7040358 |
author information missing
Guanine deaminase from rat brain. Purification, characteristics, and contribution to ammoniagenesis in the brain
J. Biochem.
1982
91: 167-176
|
| 24910588 |
Ristow M et al.:
Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS)
Dose Response
2014
12: 288-341
|
| 14767878 |
Nuttall FQ et al.:
The metabolic response to ingestion of proline with and without glucose
Metab. Clin. Exp.
2004
53: 241-246
|
| 29132502 |
Kuhl I et al.:
Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals
|
| 6894321 |
author information missing
The intercellular proline cycle
Life Sci.
1981
28: 53-58
|
| 18242653 |
Marin R et al.:
Modulation of Abeta-induced neurotoxicity by estrogen receptor alpha and other associated proteins in lipid rafts
Steroids
2008
73: 992-996
|
| 15496458 |
Acconcia F et al.:
Palmitoylation-dependent estrogen receptor alpha membrane localization: regulation by 17beta-estradiol
Mol. Biol. Cell
2005
16: 231-237
|
| 20114038 |
Jover-Mengual T et al.:
Acute estradiol protects CA1 neurons from ischemia-induced apoptotic cell death via the PI3K/Akt pathway
Brain Res.
2010
1321: 1-12
|
| 19468079 |
Prentice RL et al. et al.:
Benefits and risks of postmenopausal hormone therapy when it is initiated soon after menopause
Am. J. Epidemiol.
2009
170: 12-23
|
| 17091024 |
Naessen T et al.:
Early postmenopausal hormone therapy improves postural balance
Menopause
2007
14: 14-19
|
| 26147751 |
Li X et al.:
New Insight Into Metformin Action: Regulation of ChREBP and FOXO1 Activities in Endothelial Cells
Mol. Endocrinol.
2015
29: 1184-1194
|
| 26123139 |
Shi L et al.:
Estrogen regulation of microcephaly genes and evolution of brain sexual dimorphism in primates
BMC Evol. Biol.
2015
15: 127
|
| 3409032 |
Nadler JV et al.:
Toxicity of L-proline toward rat hippocampal neurons
Brain Res.
1988
456: 168-172
|
| 6688511 |
author information missing
Transfer of reducing equivalents into mitochondria by the interconversions of proline and delta 1-pyrroline-5-carboxylate
Arch. Biochem. Biophys.
1983
225: 95-101
|
| 25984437 |
Obayashi Y et al.:
The protection mechanism of proline from D-galactosamine hepatitis involves the early activation of ROS-eliminating pathway in the liver
Springerplus
2015
4: 199
|
| 646809 |
author information missing
Prolone metabolism in isolated rat liver cells
Biochem. J.
1978
170: 699-707
|
| 17453421 |
Marin R et al.:
Voltage-dependent anion channel (VDAC) participates in amyloid beta-induced toxicity and interacts with plasma membrane estrogen receptor alpha in septal and hippocampal neurons
Mol. Membr. Biol.
2007
24: 148-160
|
| 23877847 |
Essawy SS et al.:
Role of adenosine receptors in the anti-nociceptive effects of allopurinol in mice
Eur Rev Med Pharmacol Sci
2013
17: 1857-1863
|
| 27624384 |
Martins DF et al.:
High-Intensity Swimming Exercise Decreases Glutamate-Induced Nociception by Activation of G-Protein-Coupled Receptors Inhibiting Phosphorylated Protein Kinase A
Mol. Neurobiol.
2017
54: 5620-5631
|
| 1310675 |
Bode AM et al.:
Glyconeogenesis from L-proline involves metabolite inhibition of the glucose-6-phosphatase system
J. Biol. Chem.
1992
267: 2860-2863
|
| 29484298 |
Bowtell JL et al.:
Improved Exercise Tolerance with Caffeine Is Associated with Modulation of both Peripheral and Central Neural Processes in Human Participants
Front Nutr
2018
5: 6
|
| 18088379 |
Ferre S et al.:
An update on the mechanisms of the psychostimulant effects of caffeine
J. Neurochem.
2008
105: 1067-1079
|
| 22085758 |
Sawynok J et al.:
Caffeine inhibits antinociception by acetaminophen in the formalin test by inhibiting spinal adenosine A(1) receptors
Eur. J. Pharmacol.
2012
674: 248-254
|
| 6584881 |
author information missing
Regulation of proline and glucose transport in mouse intestine by dietary substrate levels
Proc. Natl. Acad. Sci. U.S.A.
1983
80: 7674-7677
|
| 8344917 |
Bode AM et al.:
Reciprocal effects of proline and glutamine on glycogenesis from glucose and ureagenesis in isolated, perfused rat livers
J. Biol. Chem.
1993
268
|
| 6027080 |
author information missing
Acid-base alterations and renal gluconeogenesis: effect of pH, bicarbonate concentration, and PCO2
J. Clin. Invest.
1967
46: 1172-1177
|
| 27590723 |
Ilie A et al.:
A Christianson syndrome-linked deletion mutation ((287)ES(288)) in SLC9A6 disrupts recycling endosomal function and elicits neurodegeneration and cell death
Mol Neurodegener
2016
11: 63
|
| 30296617 |
Ilie A et al.:
A potential gain-of-function variant of SLC9A6 leads to endosomal alkalinization and neuronal atrophy associated with Christianson Syndrome
Neurobiol. Dis.
2018
121: 187-204
|
| 29755574 |
Holecek M et al.:
Branched-chain amino acids in health and disease: metabolism, alterations in blood plasma, and as supplements
Nutr Metab (Lond)
2018
15: 33
|
| 15930469 |
Hutson SM et al.:
Branched-chain [corrected] amino acid metabolism: implications for establishing safe intakes
J. Nutr.
2005
135: 1557
|
| 29803540 |
Shimomura Y et al.:
Physiological and pathological roles of branched-chain amino acids in the regulation of protein and energy metabolism and neurological functions
Pharmacol. Res.
2018
133: 215-217
|
| 27010498 |
Kimball SR et al.:
Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation
Cell. Signal.
2016
28: 896-906
|
| 30379325 |
Oparija L et al.:
Anticipation of food intake induces phosphorylation switch to regulate basolateral amino acid transporter LAT4 (SLC43A2) function
|
| 30224059 |
Noguchi S et al.:
Ca(2+)-dependent inhibition of branched-chain alpha-ketoacid dehydrogenase kinase by thiamine pyrophosphate
Biochem. Biophys. Res. Commun.
2018
504: 916-920
|
| 28719620 |
Xu M et al.:
Endurance performance and energy metabolism during exercise in mice with a muscle-specific defect in the control of branched-chain amino acid catabolism
PLoS ONE
2017
12
|
| 30002133 |
Karaca M et al.:
Liver Glutamate Dehydrogenase Controls Whole-Body Energy Partitioning Through Amino Acid-Derived Gluconeogenesis and Ammonia Homeostasis
Diabetes
2018
67: 1949-1961
|
| 2583157 |
Wagenmakers AJ et al.:
Exercise-induced activation of the branched-chain 2-oxo acid dehydrogenase in human muscle
Eur J Appl Physiol Occup Physiol
1989
59: 159-167
|
| 20133434 |
She P et al.:
Disruption of BCAA metabolism in mice impairs exercise metabolism and endurance
J. Appl. Physiol.
2010
108: 941-949
|
| 649595 |
author information missing
The origin of alanine produced in skeletal muscle
J. Biol. Chem.
1978
253: 3677-3684
|
| 28779141 |
Saiki S et al. et al.:
Decreased long-chain acylcarnitines from insufficient beta-oxidation as potential early diagnostic markers for Parkinsons disease
Sci Rep
2017
7: 7328
|
| 25506168 |
Topcu Y et al.:
Importance of acylcarnitine profile analysis for disorders of lipid metabolism in adolescent patients with recurrent rhabdomyolysis: Report of two cases
Ann Indian Acad Neurol
2014
17: 437-440
|
| 20634953 |
Lehmann R et al. et al.:
Medium chain acylcarnitines dominate the metabolite pattern in humans under moderate intensity exercise and support lipid oxidation
PLoS ONE
2010
5
|
| 19720082 |
Jones LL et al.:
Acylcarnitines: role in brain
Prog. Lipid Res.
2010
49: 61-75
|
| 28526869 |
Morkholt AS et al.:
Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism
Sci Rep
2017
7: 2158
|
| 21518883 |
Kimura I et al.:
Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)
Proc. Natl. Acad. Sci. U.S.A.
2011
108: 8030-8035
|
| 18162502 |
Lai CQ et al.:
PPARGC1A variation associated with DNA damage, diabetes, and cardiovascular diseases: the Boston Puerto Rican Health Study
Diabetes
2008
57: 809-816
|
| 29187824 |
Supruniuk E et al.:
The Implication of PGC-1alpha on Fatty Acid Transport across Plasma and Mitochondrial Membranes in the Insulin Sensitive Tissues
Front Physiol
2017
8: 923
|
| 29747667 |
El Ayed M et al.:
Protective effect of grape seed and skin extract against high-fat diet-induced dyshomeostasis of energetic metabolism in rat lung
Lipids Health Dis
2018
17: 109
|
| 2185659 |
Tsuchiya M et al.:
Increased de novo purine synthesis by insulin through selective enzyme induction in primary cultured rat hepatocytes
Am. J. Physiol.
1990
258: C841-C848
|
| 28600292 |
Reyat JS et al.:
ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration
J. Immunol.
2017
199: 666-676
|
| 8413795 |
Yamamoto T et al.:
Effect of lactate infusion on renal transport of purine bases and oxypurinol
Nephron
1993
65: 73-76
|
| 26338711 |
Fado R et al.:
Novel Regulation of the Synthesis of alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Subunit GluA1 by Carnitine Palmitoyltransferase 1C (CPT1C) in the Hippocampus
J. Biol. Chem.
2015
290
|
| 6219439 |
Vaz FM et al.:
Carnitine biosynthesis in mammals
Biochem. J.
2002
361: 417-429
|
| 20306513 |
Strijbis K et al.:
Enzymology of the carnitine biosynthesis pathway
IUBMB Life
2010
62: 357-362
|
| 24363437 |
Luu W et al.:
Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesis
J. Lipid Res.
2014
55: 410-420
|
| 28688036 |
Ishimoto T et al.:
Carnitine/Organic Cation Transporter OCTN1 Negatively Regulates Activation in Murine Cultured Microglial Cells
Neurochem. Res.
2018
43: 107-119
|
| 21576264 |
Zaugg K et al. et al.:
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
Genes Dev.
2011
25: 1041-1051
|
| 28004106 |
Ma C et al.:
Resveratrol upregulates SOCS1 production by lipopolysaccharide-stimulated RAW264.7 macrophages by inhibiting miR-155
Int. J. Mol. Med.
2017
39: 231-237
|
| 28401267 |
Liu N et al.:
Paeonol protects against TNF-alpha-induced proliferation and cytokine release of rheumatoid arthritis fibroblast-like synoviocytes by upregulating FOXO3 through inhibition of miR-155 expression
Inflamm. Res.
2017
66: 603-610
|
| 29479888 |
author information missing
Decreased Serum Level of miR-155 is Associated with Obesity and its Related Metabolic Traits
Clin. Lab.
2018
64: 77-84
|
| 30399324 |
Li H et al.:
TNF-alpha is upregulated in subacute thyroiditis and stimulates expression of miR-155-5p in thyroid follicle cells
Discov Med
2018
26: 67-77
|
| 20844277 |
Lappas M et al.:
SIRT1 is a novel regulator of key pathways of human labor
Biol. Reprod.
2011
84: 167-178
|
| 23394815 |
Krugel U et al.:
Antidepressant effects of TNF-alpha blockade in an animal model of depression
J Psychiatr Res
2013
47: 611-616
|
| 30569819 |
Parkin GM et al.:
Plasma TNF alpha is a predictor of persisting symptoms post-concussion in children
|
| 21622568 |
Lee K et al.:
Mitochondrial carnitine palmitoyltransferase 1a (CPT1a) is part of an outer membrane fatty acid transfer complex
J. Biol. Chem.
2011
286
|
| 22908270 |
Dwyer JR et al. et al.:
Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum
Proc. Natl. Acad. Sci. U.S.A.
2012
109
|
| 23209300 |
Thakran S et al.:
Role of sirtuin 1 in the regulation of hepatic gene expression by thyroid hormone
J. Biol. Chem.
2013
288: 807-818
|
| 23295259 |
Peter Slotte J et al.:
Molecular properties of various structurally defined sphingomyelins -- correlation of structure with function
Prog. Lipid Res.
2013
52: 206-219
|
| 30619097 |
Liu Y et al.:
17beta-Estradiol Promotes Apoptosis in Airway Smooth Muscle Cells Through CD38/SIRT1/p53 Pathway
Front Endocrinol (Lausanne)
2018
9: 770
|
| 29635338 |
van Weeghel M et al. et al.:
Increased cardiac fatty acid oxidation in a mouse model with decreased malonyl-CoA sensitivity of CPT1B
Cardiovasc. Res.
2018
114: 1324-1334
|
| 16950137 |
Finck BN et al.:
Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway
Cell Metab.
2006
4: 199-210
|
| 16651524 |
Wolfgang MJ et al.:
The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis
Proc. Natl. Acad. Sci. U.S.A.
2006
103: 7282-7287
|
| 22539351 |
Carrasco P et al. et al.:
Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition
J. Biol. Chem.
2012
287
|
| 25213552 |
Yuan H et al.:
Exercise increases the binding of MEF2A to the Cpt1b promoter in mouse skeletal muscle
Acta Physiol (Oxf)
2014
212: 283-292
|
| 15448143 |
Engel K et al.:
Identification and characterization of a novel monoamine transporter in the human brain
J. Biol. Chem.
2004
279
|
| 25002497 |
Davies SK et al. et al.:
Effect of sleep deprivation on the human metabolome
Proc. Natl. Acad. Sci. U.S.A.
2014
111
|
| 23303207 |
Valladares R et al.:
Lactobacillus johnsonii inhibits indoleamine 2,3-dioxygenase and alters tryptophan metabolite levels in BioBreeding rats
FASEB J.
2013
27: 1711-1720
|
| 27107761 |
Kalani M et al.:
Lactobacillus acidophilus Increases the Anti-apoptotic Micro RNA-21 and Decreases the Pro-inflammatory Micro RNA-155 in the LPS-Treated Human Endothelial Cells
Probiotics Antimicrob Proteins
2016
8: 61-72
|
| 28214900 |
author information missing
MiR-21 Regulates TNF-alpha-Induced CD40 Expression via the SIRT1-NF-kappaB Pathway in Renal Inner Medullary Collecting Duct Cells
Cell. Physiol. Biochem.
2017
41: 124-136
|
| 26579440 |
Yang Z et al.:
Emerging role of microRNAs in lipid metabolism
Acta Pharm Sin B
2015
5: 145-150
|
| 24301787 |
Kang M et al.:
Inhibitory effect of microRNA-24 on fatty acid-binding protein expression on 3T3-L1 adipocyte differentiation
Genet. Mol. Res.
2013
12: 5267-5277
|
| 28806138 |
Nguyen TB et al.:
Lipid droplets and lipotoxicity during autophagy
Autophagy
2017
13: 2002-2003
|
| 25349648 |
He S et al. et al.:
Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety
ACS Med Chem Lett
2014
5: 1082-1087
|
| 10552934 |
Yang XH et al.:
PFM1 (PRDM4), a new member of the PR-domain family, maps to a tumor suppressor locus on human chromosome 12q23-q24.1
Genomics
1999
61: 319-325
|
| 9473344 |
Hoff HB 3rd et al.:
DBI-1, a novel gene related to the notch family, modulates mitogenic response to insulin-like growth factor 1
Exp. Cell Res.
1998
238: 359-370
|
| 29843043 |
Wang J et al.:
Resveratrol inhibits pulmonary fibrosis by regulating miR-21 through MAPK/AP-1 pathways
Biomed. Pharmacother.
2018
105: 37-44
|
| 30737432 |
Rubtsova MP et al.:
Integrator is a key component of human telomerase RNA biogenesis
Sci Rep
2019
9: 1701
|
| 17310990 |
Buchsbaum S et al.:
Human INT6 interacts with MCM7 and regulates its stability during S phase of the cell cycle
Oncogene
2007
26: 5132-5144
|
| 17001306 |
Erkeland SJ et al.:
Novel role of WD40 and SOCS box protein-2 in steady-state distribution of granulocyte colony-stimulating factor receptor and G-CSF-controlled proliferation and differentiation signaling
Oncogene
2007
26: 1985-1994
|
| 28544111 |
Guo Y et al.:
Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-SIRT1 pathway
Aging Cell
2017
16: 837-846
|
| 25356641 |
Park MS et al.:
Crystal structure of human protein N-terminal glutamine amidohydrolase, an initial component of the N-end rule pathway
PLoS ONE
2014
9
|
| 30626964 |
Wilkinson AW et al. et al.:
SETD3 is an actin histidine methyltransferase that prevents primary dystocia
Nature
2019
565: 372-376
|
| 26030842 |
Cooper SE et al.:
A fluorescent bimolecular complementation screen reveals MAF1, RNF7 and SETD3 as PCNA-associated proteins in human cells
Cell Cycle
2015
14: 2509-2519
|
| 29283043 |
Ranchoux B et al.:
Endothelial dysfunction in pulmonary arterial hypertension: an evolving landscape (2017 Grover Conference Series)
Pulm Circ
2018
8
|
| 22086720 |
Stunkel W et al.:
Sirtuin 1 (SIRT1): the misunderstood HDAC
J Biomol Screen
2011
16: 1153-1169
|
| 15107829 |
Frontelo P et al.:
Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression
Oncogene
2004
23: 5242-5251
|
| 20660480 |
Han L et al.:
SIRT1 is regulated by a PPAR{gamma}-SIRT1 negative feedback loop associated with senescence
Nucleic Acids Res.
2010
38: 7458-7471
|
| 26208095 |
Green DE et al.:
PPARgamma Ligands Attenuate Hypoxia-Induced Proliferation in Human Pulmonary Artery Smooth Muscle Cells through Modulation of MicroRNA-21
PLoS ONE
2015
10
|
| 27447824 |
Jablonski KA et al.:
Control of the Inflammatory Macrophage Transcriptional Signature by miR-155
PLoS ONE
2016
11
|
| 14702045 |
Garcia-Cao M et al.:
Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases
Nat Genet
2004
36: 94-99
|
| 26725323 |
Han XR et al.:
KDM2B/FBXL10 targets c-Fos for ubiquitylation and degradation in response to mitogenic stimulation
Oncogene
2016
35: 4179-4190
|
| 29763382 |
Kang JY et al.:
KDM2B is a histone H3K79 demethylase and induces transcriptional repression via sirtuin-1-mediated chromatin silencing
FASEB J.
2018
32: 5737-5750
|
| 25533466 |
Inagaki T et al. et al.:
The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis
J. Biol. Chem.
2015
290: 4163-4177
|
| 22863012 |
Qiang L et al.:
Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Ppargamma
Cell
2012
150: 620-632
|
| 27598236 |
Li DD et al.:
High-affinity small molecular blockers of mixed lineage leukemia 1 (MLL1)-WDR5 interaction inhibit MLL1 complex H3K4 methyltransferase activity
Eur J Med Chem
2016
124: 480-489
|
| 25751424 |
Aguilar-Arnal L et al.:
NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1
Nat. Struct. Mol. Biol.
2015
22: 312-318
|
| 21047783 |
Park UH et al.:
Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}
J. Biol. Chem.
2011
286: 1354-1363
|
| 28884217 |
Searle NE et al.:
Critical genomic regulation mediated by Enhancer of Polycomb
Curr. Genet.
2018
64: 147-154
|
| 25625517 |
Czarny P et al.:
Autophagy in DNA damage response
Int J Mol Sci
2015
16: 2641-2662
|
| 26470790 |
Zekas E et al.:
Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER
BMC Cancer
2015
15: 702
|
| 30542149 |
Greenhill C et al.:
Circadian protein affects mTORC1 activity
Nat Rev Endocrinol
2019
15: 65
|
| 18288196 |
Arany Z et al. et al.:
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha
Nature
2008
451: 1008-1012
|
| 18765803 |
Willcox BJ et al.:
FOXO3A genotype is strongly associated with human longevity
Proc. Natl. Acad. Sci. U.S.A.
2008
105
|
| 24162845 |
Gerhart-Hines Z et al. et al.:
The nuclear receptor Rev-erbalpha controls circadian thermogenic plasticity
Nature
2013
503: 410-413
|
| 25969949 |
Vaissiere A et al.:
Molecular mechanisms of transcriptional control by Rev-erbalpha: An energetic foundation for reconciling structure and binding with biological function
Protein Sci.
2015
24: 1129-1146
|
| 27317762 |
Liu Z et al.:
Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice
J. Lipid Res.
2016
57: 1373-1381
|
| 26200012 |
Yuk JM et al. et al.:
Orphan Nuclear Receptor ERRalpha Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation
Immunity
2015
43: 80-91
|
| 28531963 |
He L et al.:
MiR-19b and miR-16 cooperatively signaling target the regulator ADRA1A in Hypertensive heart disease
Biomed. Pharmacother.
2017
91: 1178-1183
|
| 19881910 |
Klinge CM et al.:
Estrogen Regulation of MicroRNA Expression
Curr. Genomics
2009
10: 169-183
|
| 18701644 |
Liu Q et al.:
miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes
Nucleic Acids Res.
2008
36: 5391-5404
|
| 1932220 |
Wallerstein R Jr et al.:
Use of blood and blood products for supportive care in cancer treatment
Curr Opin Oncol
1991
3: 628-633
|
| 23026212 |
Al Rayyan N et al.:
Two single nucleotide polymorphisms in the human nescient helix-loop-helix 2 (NHLH2) gene reduce mRNA stability and DNA binding
Gene
2013
512: 134-142
|
| 24971323 |
Lei H et al.:
A functional polymorphism of the MAOA gene modulates spontaneous brain activity in pons
Biomed Res Int
2014
2014
|
| 18815487 |
Good DJ et al.:
Nhlh2: a basic helix-loop-helix transcription factor controlling physical activity
Exerc Sport Sci Rev
2008
36: 187-192
|
| 19168625 |
McDermott R et al.:
Monoamine oxidase A gene (MAOA) predicts behavioral aggression following provocation
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 2118-2123
|
| 23684566 |
Good DJ et al.:
NHLH2: at the intersection of obesity and fertility
Trends Endocrinol. Metab.
2013
24: 385-390
|
| 24486192 |
Al Rayyan N et al.:
Leptin signaling regulates hypothalamic expression of nescient helix-loop-helix 2 (Nhlh2) through signal transducer and activator 3 (Stat3)
Mol. Cell. Endocrinol.
2014
384: 134-142
|
| 28090353 |
Perng W et al.:
Leptin, acylcarnitine metabolites and development of adiposity in the Rhea mother-child cohort in Crete, Greece
Obes Sci Pract
2016
2: 471-476
|
| 30246441 |
Cote I et al.:
Oestradiol and leptin have separate but additive anorexigenic effects and differentially target fat mass in rats
J. Neuroendocrinol.
2018
30
|
| 24893614 |
Kranenburg LC et al.:
The effect of long-term oral L-carnitine administration on insulin sensitivity, glucose disposal, plasma concentrations of leptin and acylcarnitines, and urinary acylcarnitine excretion in warmblood horses
Vet Q
2014
34: 85-91
|
| 29109080 |
Mora C et al.:
Central leptin regulates heart lipid content by selectively increasing PPAR beta/delta expression
J. Endocrinol.
2018
236: 43-56
|
| 26236282 |
Sasaki T et al.:
Age-Associated Weight Gain, Leptin, and SIRT1: A Possible Role for Hypothalamic SIRT1 in the Prevention of Weight Gain and Aging through Modulation of Leptin Sensitivity
Front Endocrinol (Lausanne)
2015
6: 109
|
| 30605688 |
Agajanian MJ et al. et al.:
WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop
Cell Rep
2019
26: 79-93.e8
|
| 21926997 |
Long JZ et al.:
Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids
Nat. Chem. Biol.
2011
7: 763-765
|
| 28442777 |
Zha W et al.:
Serotonin transporter deficiency drives estrogen-dependent obesity and glucose intolerance
Sci Rep
2017
7: 1137
|
| 24058635 |
de Oliveira M et al.:
Triiodothyronine increases mRNA and protein leptin levels in short time in 3T3-L1 adipocytes by PI3K pathway activation
PLoS ONE
2013
8
|
| 25993072 |
Oliveira Md et al.:
Triiodothyronine modulates the expression of leptin and adiponectin in 3T3-L1 adipocytes
Einstein (Sao Paulo)
2015
13: 72-78
|
| 25762784 |
Liu Y et al.:
NF-kappaB downregulates Cbl-b through binding and suppressing Cbl-b promoter in T cell activation
J. Immunol.
2015
194: 3778-3783
|
| 14758344 |
Wolkowicz P et al.:
Activation of leptin expression by an inhibitor of carnitine palmitoyltransferase-1
Int. J. Obes. Relat. Metab. Disord.
2004
28: 649-651
|
| 15459119 |
Gremlich S et al.:
Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation
Endocrinology
2005
146: 375-382
|
| 22978602 |
Carland JE et al.:
Oleoyl-L-carnitine inhibits glycine transport by GlyT2
Br. J. Pharmacol.
2013
168: 891-902
|
| 10876004 |
Roschinger W et al.:
Carnitine-acylcarnitine translocase deficiency: metabolic consequences of an impaired mitochondrial carnitine cycle
Clin. Chim. Acta
2000
298: 55-68
|
| 29792983 |
Szili B et al.:
Impact of genetic influence on serum total- and free 25-hydroxyvitamin-D in humans
J. Steroid Biochem. Mol. Biol.
2018
183: 62-67
|
| 12547821 |
Hara N et al.:
Molecular identification of human glutamine- and ammonia-dependent NAD synthetases. Carbon-nitrogen hydrolase domain confers glutamine dependency
J. Biol. Chem.
2003
278
|
| 18281923 |
Rinaldo P et al.:
Acylcarnitine profile analysis
Genet. Med.
2008
10: 151-156
|
| 26149120 |
Xu X et al.:
Vitamin D Deficiency in Uygurs and Kazaks Is Associated with Polymorphisms in CYP2R1 and DHCR7/NADSYN1 Genes
Med. Sci. Monit.
2015
21: 1960-1968
|
| 25217626 |
Wang Z et al.:
A newly identified myomegalin isoform functions in Golgi microtubule organization and ER-Golgi transport
J Cell Sci
2014
127: 4904-4917
|
| 11134006 |
Verde I et al.:
Myomegalin is a novel protein of the golgi/centrosome that interacts with a cyclic nucleotide phosphodiesterase
J. Biol. Chem.
2001
276
|
| 17403373 |
Sano H et al.:
Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane
Cell Metab.
2007
5: 293-303
|
| 17208202 |
Ishikura S et al.:
Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells
Biochem. Biophys. Res. Commun.
2007
353: 1074-1079
|
| 20418485 |
Ahn J et al. et al.:
Genome-wide association study of circulating vitamin D levels
Hum. Mol. Genet.
2010
19: 2739-2745
|
| 29237719 |
Schmid FM et al.:
IFT20 modulates ciliary PDGFRalpha signaling by regulating the stability of Cbl E3 ubiquitin ligases
J. Cell Biol.
2018
217: 151-161
|
| 18317232 |
Primassin S et al.:
Carnitine supplementation induces acylcarnitine production in tissues of very long-chain acyl-CoA dehydrogenase-deficient mice, without replenishing low free carnitine
Pediatr. Res.
2008
63: 632-637
|
| 28257739 |
Weaver CA et al.:
Candidate gene analyses of 3-dimensional dentoalveolar phenotypes in subjects with malocclusion
Am J Orthod Dentofacial Orthop
2017
151: 539-558
|
| 25732600 |
Pioli PD et al.:
Fatal autoimmunity results from the conditional deletion of Snai2 and Snai3
Cell. Immunol.
2015
295: 1-18
|
| 20622002 |
Tili E et al.:
Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD
Carcinogenesis
2010
31: 1561-1566
|
| 28765959 |
Xu L et al.:
MicroRNA-21 regulates the proliferation and apoptosis of cervical cancer cells via tumor necrosis factor-alpha
Mol Med Rep
2017
16: 4659-4663
|
| 14719046 |
Wichers MC et al.:
The role of indoleamine 2,3-dioxygenase (IDO) in the pathophysiology of interferon-alpha-induced depression
J Psychiatry Neurosci
2004
29: 11-17
|
| 20970343 |
Funato Y et al.:
Nucleoredoxin sustains Wnt/beta-catenin signaling by retaining a pool of inactive dishevelled protein
Curr Biol
2010
20: 1945-1952
|
| 15494706 |
Wichers MC et al.:
IDO and interferon-alpha-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity
Mol. Psychiatry
2005
10: 538-544
|
| 30936978 |
Gu Z et al.:
Therapeutic effect of resveratrol on mice with depression
Exp Ther Med
2019
17: 3061-3064
|
| 16764867 |
Lechward K et al.:
Interaction of nucleoredoxin with protein phosphatase 2A
FEBS Lett.
2006
580: 3631-3637
|
| 24120946 |
Funato Y et al.:
Nucleoredoxin regulates glucose metabolism via phosphofructokinase 1
Biochem. Biophys. Res. Commun.
2013
440: 737-742
|
| 10903915 |
Hirota K et al.:
Nucleoredoxin, glutaredoxin, and thioredoxin differentially regulate NF-kappaB, AP-1, and CREB activation in HEK293 cells
Biochem Biophys Res Commun
2000
274: 177-182
|
| 25548260 |
Bahn YJ et al.:
Nucleoredoxin promotes adipogenic differentiation through regulation of Wnt/beta-catenin signaling
J. Lipid Res.
2015
56: 294-303
|
| 29482657 |
Lin Z et al.:
Fatty acid oxidation promotes reprogramming by enhancing oxidative phosphorylation and inhibiting protein kinase C
Stem Cell Res Ther
2018
9: 47
|
| 23390957 |
Kim SJ et al.:
Incretin-stimulated interaction between beta-cell Kv1.5 and Kvbeta2 channel proteins involves acetylation/deacetylation by CBP/SirT1
Biochem J
2013
451: 227-234
|
| 28514442 |
Huttlin EL et al. et al.:
Architecture of the human interactome defines protein communities and disease networks
Nature
2017
545: 505-509
|
| 24457600 |
Cao Q et al. et al.:
The central role of EED in the orchestration of polycomb group complexes
Nat Commun
2014
5: 3127
|
| 22094255 |
O'Hagan HM et al. et al.:
Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands
Cancer Cell
2011
20: 606-619
|
| 28179152 |
Hansen CH et al.:
The six most widely used selective serotonin reuptake inhibitors decrease androgens and increase estrogens in the H295R cell line
Toxicol In Vitro
2017
41: 1-11
|
| 28298427 |
Sokolina K et al. et al.:
Systematic protein-protein interaction mapping for clinically relevant human GPCRs
Mol. Syst. Biol.
2017
13: 918
|
| 23106887 |
Luo QF et al.:
Identification of Nedd4 as a novel regulator in Hedgehog signaling
Chin Med J (Engl)
2012
125: 3851-3855
|
| 22773947 |
Al-Salihi MA et al.:
USP11 augments TGFbeta signalling by deubiquitylating ALK5
Open Biol
2012
2
|
| 15160261 |
Sanchez C et al.:
Escitalopram versus citalopram: the surprising role of the R-enantiomer
Psychopharmacology (Berl.)
2004
174: 163-176
|
| 17885600 |
Mnie-Filali O et al.:
R-citalopram prevents the neuronal adaptive changes induced by escitalopram
Neuroreport
2007
18: 1553-1556
|
| 22683847 |
Iossifov I et al. et al.:
The contribution of de novo coding mutations to autism spectrum disorder
Nature
2014
515: 216-221
|
| 21730131 |
Kim NG et al.:
E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components
Proc. Natl. Acad. Sci. U.S.A.
2011
108
|
| 25070368 |
Ribeiro-Rodrigues TM et al.:
AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions
FASEB J
2014
28: 4629-4641
|
| 28875039 |
Yuan F et al.:
Nucleolar and coiled-body phosphoprotein 1 (NOLC1) regulates the nucleolar retention of TRF2
Cell Death Discov
2017
3: 17043
|
| 8972203 |
Miau LH et al.:
Identification and characterization of a nucleolar phosphoprotein, Nopp140, as a transcription factor
Mol. Cell. Biol.
1997
17: 230-239
|
| 10877005 |
von Bahr C et al.:
Fluvoxamine but not citalopram increases serum melatonin in healthy subjects-- an indication that cytochrome P450 CYP1A2 and CYP2C19 hydroxylate melatonin
Eur. J. Clin. Pharmacol.
2000
56: 123-127
|
| 21464124 |
Gupta-Rossi N et al.:
The adaptor-associated kinase 1, AAK1, is a positive regulator of the Notch pathway
J. Biol. Chem.
2011
286
|
| 9566597 |
Anton-Tay F et al.:
In vitro stimulation of protein kinase C by melatonin
Neurochem. Res.
1998
23: 601-606
|
| 24914052 |
deHaro D et al.:
Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at night
Nucleic Acids Res.
2014
42: 7694-7707
|
| 24956284 |
Tocharus C et al.:
Melatonin enhances adult rat hippocampal progenitor cell proliferation via ERK signaling pathway through melatonin receptor
Neuroscience
2014
275: 314-321
|
| 17494869 |
Henderson DM et al.:
A novel AAK1 splice variant functions at multiple steps of the endocytic pathway
Mol. Biol. Cell
2007
18: 2698-2706
|
| 24901414 |
Park SW et al.:
Differential effects of antidepressant drugs on mTOR signalling in rat hippocampal neurons
Int. J. Neuropsychopharmacol.
2014
17: 1831-1846
|
| 25950587 |
Bai L et al.:
MicroRNA-21 Regulates PI3K/Akt/mTOR Signaling by Targeting TGFbetaI during Skeletal Muscle Development in Pigs
PLoS ONE
2015
10
|
| 30413707 |
Zhang L et al.:
Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling
Nat Commun
2018
9: 4722
|
| 19208814 |
Page DT et al.:
Haploinsufficiency for Pten and Serotonin transporter cooperatively influences brain size and social behavior
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 1989-1994
|
| 28755312 |
Abdelraheim SR et al.:
Mouse Nudt13 is a Mitochondrial Nudix Hydrolase with NAD(P)H Pyrophosphohydrolase Activity
Protein J.
2017
36: 425-432
|
| 21566257 |
Valerio A et al.:
Branched-chain amino acids, mitochondrial biogenesis, and healthspan: an evolutionary perspective
Aging (Albany NY)
2011
3: 464-478
|
| 10471790 |
Eden A et al.:
Involvement of branched-chain amino acid aminotransferase (Bcat1/Eca39) in apoptosis
FEBS Lett.
1999
457: 255-261
|
| 7714781 |
Eison AS et al.:
Melatonin agonists modulate 5-HT2A receptor-mediated neurotransmission: behavioral and biochemical studies in the rat
J. Pharmacol. Exp. Ther.
1995
273: 304-308
|
| 638156 |
author information missing
The effect of acylcarnitines on the oxidation of branched chain alpha-keto acids in mitochondria
Biochim. Biophys. Acta
1978
528: 269-275
|
| 10655160 |
Roe DS et al.:
Evidence for a short-chain carnitine-acylcarnitine translocase in mitochondria specifically related to the metabolism of branched-chain amino acids
Mol. Genet. Metab.
2000
69: 69-75
|
| 17500595 |
Kaltenbach LS et al. et al.:
Huntingtin interacting proteins are genetic modifiers of neurodegeneration
PLoS Genet.
2007
3: e82
|
| 20153737 |
Amaral AU et al.:
Alpha-ketoisocaproic acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain
Brain Res.
2010
1324: 75-84
|
| 17683626 |
van den Bosch HM et al.:
Gene expression of transporters and phase I/II metabolic enzymes in murine small intestine during fasting
BMC Genomics
2007
8: 267
|
| 24650119 |
Ramirez-Rodriguez G et al.:
Melatonin synergizes with citalopram to induce antidepressant-like behavior and to promote hippocampal neurogenesis in adult mice
J. Pineal Res.
2014
56: 450-461
|
| 21689104 |
Jiang X et al.:
Acetyl-L-carnitine ameliorates spatial memory deficits induced by inhibition of phosphoinositol-3 kinase and protein kinase C
J. Neurochem.
2011
118: 864-878
|
| 19343720 |
Law IK et al.:
Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins
Proteomics
2009
9: 2444-2456
|
| 16120479 |
Schilling B et al.:
Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mitochondria
Biochim. Biophys. Acta
2006
1762: 213-222
|
| 29568061 |
Liu X et al.:
An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations
Nat Commun
2018
9: 1188
|
| 30462309 |
Ivanochko D et al. et al.:
Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex
Nucleic Acids Res.
2019
47: 1225-1238
|
| 30833792 |
Hubel P et al. et al.:
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape
Nat. Immunol.
2019
20: 493-502
|
| 27499296 |
Floyd BJ et al. et al.:
Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function
Mol. Cell
2016
63: 621-632
|
| 29656893 |
Gupta R et al.:
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Cell
2018
173: 972-988.e23
|
| 26752685 |
Scholz CC et al. et al.:
FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1
PLoS Biol.
2016
14
|
| 24344204 |
Guarani V et al.:
TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex
Mol. Cell. Biol.
2014
34: 847-861
|
| 16615898 |
Kislinger T et al. et al.:
Global survey of organ and organelle protein expression in mouse: combined proteomic and transcriptomic profiling
Cell
2006
125: 173-186
|
| 26465331 |
Grose JH et al. et al.:
Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome
PLoS ONE
2015
10
|
| 28739822 |
VandeKopple MJ et al.:
Stress-responsive HILPDA is necessary for thermoregulation during fasting
J. Endocrinol.
2017
235: 27-38
|
| 27266874 |
Kobayashi M et al.:
Detection of differentially expressed candidate genes for a fatty liver QTL on mouse chromosome 12
BMC Genet.
2016
17: 73
|
| 21816276 |
Peterson TR et al.:
mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway
Cell
2011
146: 408-420
|
| 22096579 |
Milkereit R et al.:
A role for the ubiquitin ligase Nedd4 in membrane sorting of LAPTM4 proteins
PLoS ONE
2011
6
|
| 28405875 |
Bradley RM et al.:
Acute Fasting Induces Expression of Acylglycerophosphate Acyltransferase (AGPAT) Enzymes in Murine Liver, Heart, and Brain
Lipids
2017
52: 457-461
|
| 19965873 |
Hirst J et al.:
Contributions of epsinR and gadkin to clathrin-mediated intracellular trafficking
Mol. Biol. Cell
2015
26: 3085-3103
|
| 22689987 |
Maritzen T et al.:
Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex
Proc. Natl. Acad. Sci. U.S.A.
2012
109
|
| 28658630 |
Mertins P et al. et al.:
An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling
Cell Rep
2017
19: 2853-2866
|
| 20303945 |
Szkudelska K et al.:
Resveratrol, obesity and diabetes
Eur. J. Pharmacol.
2010
635: 1-8
|
| 20235789 |
Morag A et al.:
Human lymphoblastoid cell line panels: novel tools for assessing shared drug pathways
Pharmacogenomics
2010
11: 327-340
|
| 30660999 |
Yamaji T et al.:
A CRISPR Screen Identifies LAPTM4A and TM9SF Proteins as Glycolipid-Regulating Factors
iScience
2019
11: 409-424
|
| 26624014 |
Schachtner H et al.:
Loss of Gadkin Affects Dendritic Cell Migration In Vitro
PLoS ONE
2015
10
|
| 23171547 |
Loke YJ et al.:
The Peri/postnatal Epigenetic Twins Study (PETS)
Twin Res Hum Genet
2013
16: 13-20
|
| 11342119 |
Huang Y et al.:
Cloning and characterization of a novel human leptin receptor overlapping transcript-like 1 gene (LEPROTL1)
Biochim. Biophys. Acta
2001
1517: 327-331
|
| 19907080 |
Touvier T et al.:
LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice
J. Clin. Invest.
2009
119: 3830-3838
|
| 12515382 |
Ingelfinger D et al.:
The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci
RNA
2002
8: 1489-1501
|
| 24352420 |
Jonas S et al.:
The role of disordered protein regions in the assembly of decapping complexes and RNP granules
Genes Dev.
2013
27: 2628-2641
|
| 11514237 |
De Nys K et al.:
Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase
Biochim. Biophys. Acta
2001
1533: 66-72
|
| 15465819 |
de Melker AA et al.:
Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment
J. Biol. Chem.
2004
279
|
| 29330351 |
Latorre E et al.:
The VEGFA156b isoform is dysregulated in senescent endothelial cells and may be associated with prevalent and incident coronary heart disease
Clin. Sci.
2018
132: 313-325
|
| 30121577 |
Wang Q et al.:
Inhibition of PPARgamma, adipogenesis and insulin sensitivity by MAGED1
J. Endocrinol.
2018
239: 167-180
|
| 20228063 |
Wu J et al.:
A novel C53/LZAP-interacting protein regulates stability of C53/LZAP and DDRGK domain-containing Protein 1 (DDRGK1) and modulates NF-kappaB signaling
J. Biol. Chem.
2010
285
|
| 31393949 |
Yamase K et al.:
Mouse TMCO5 is localized to the manchette microtubules involved in vesicle transfer in the elongating spermatids
PLoS One
2019
14
|
| 9860297 |
Triepels R et al.:
The nuclear-encoded human NADH:ubiquinone oxidoreductase NDUFA8 subunit: cDNA cloning, chromosomal localization, tissue distribution, and mutation detection in complex-I-deficient patients
Hum. Genet.
1998
103: 557-563
|
| 21310150 |
Szklarczyk R et al.:
NDUFB7 and NDUFA8 are located at the intermembrane surface of complex I
FEBS Lett.
2011
585: 737-743
|
| 10330338 |
Smeitink J et al.:
Human mitochondrial complex I in health and disease
Am. J. Hum. Genet.
1999
64: 1505-1510
|
| 22824754 |
Mazzoccoli G et al.:
REV-ERBalpha and the clock gene machinery in mouse peripheral tissues: a possible role as a synchronizing hinge
J. Biol. Regul. Homeost. Agents
2012
26: 265-276
|
| 16754977 |
Herde P et al.:
The purification, crystallization and preliminary structural characterization of human MAWDBP, a member of the phenazine biosynthesis-like protein family
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.
2006
62: 546-549
|
| 11355021 |
Iriyama C et al.:
Cloning and sequencing of a novel human gene which encodes a putative hydroxylase
J. Hum. Genet.
2001
46: 289-292
|
| 15902099 |
Solomon SS et al.:
Proteome of H-411E (liver) cells exposed to insulin and tumor necrosis factor-alpha: analysis of proteins involved in insulin resistance
J. Lab. Clin. Med.
2005
145: 275-283
|
| 15883201 |
Miyamoto T et al.:
Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice
J. Cell Biol.
2005
169: 527-538
|
| 20874812 |
Sohda M et al.:
Interaction of Golgin-84 with the COG complex mediates the intra-Golgi retrograde transport
Traffic
2010
11: 1552-1566
|
| 31515672 |
Dianatpour S et al.:
Novel Point Mutations of CITED2 Gene Are Associated with Non-familial Congenital Heart Disease (CHD) in Sporadic Pediatric Patients
|
| 25865758 |
Lehalle D et al.:
A review of craniofacial disorders caused by spliceosomal defects
Clin Genet
2015
88: 405-415
|
| 16916645 |
Machida YJ et al.:
UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation
Mol Cell
2006
23: 589-596
|
| 24788516 |
Dias J et al.:
Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex
Genes Dev
2014
28: 929-942
|
| 24301056 |
Docker D et al.:
Further delineation of the SATB2 phenotype
Eur J Hum Genet
2014
22: 1034-1039
|
| 30659610 |
Huang YT et al.:
ROS- and HIF1alpha-dependent IGFBP3 upregulation blocks IGF1 survival signaling and thereby mediates high-glucose-induced cardiomyocyte apoptosis
J. Cell. Physiol.
2019
234
|
| 23263282 |
Fernandez-Saiz V et al. et al.:
SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma
Nat Cell Biol
2013
15: 72-81
|
| 31009856 |
Li R et al.:
E3 ligase ASB8 promotes porcine reproductive and respiratory syndrome virus proliferation by stabilizing the viral Nsp1alpha protein and degrading host IKKbeta kinase
Virology
2019
532: 55-68
|
| 26748711 |
Greifenberg AK et al.:
Structural and Functional Analysis of the Cdk13/Cyclin K Complex
Cell Rep
2016
14: 320-331
|
| 25996873 |
Shambharkar PB et al.:
TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis
PLoS ONE
2015
10
|
| 15647320 |
Fan T et al.:
Lsh controls silencing of the imprinted Cdkn1c gene
Development
2005
132: 635-644
|
| 11325543 |
Geiman TM et al.:
Lsh, a SNF2 family member, is required for normal murine development
Biochim. Biophys. Acta
2001
1526: 211-220
|
| 30741923 |
Cho JJ et al. et al.:
Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation
Nat Commun
2019
10: 701
|
| 24444792 |
Osorio C et al.:
Selective regulation of axonal growth from developing hippocampal neurons by tumor necrosis factor superfamily member APRIL
Mol. Cell. Neurosci.
2014
59: 24-36
|
| 30097772 |
Tebar F et al.:
GTPases Rac1 and Ras Signaling from Endosomes
Prog. Mol. Subcell. Biol.
2018
57: 65-105
|
| 9738472 |
Partiseti M et al.:
Cloning and characterization of a novel human inwardly rectifying potassium channel predominantly expressed in small intestine
FEBS Lett.
1998
434: 171-176
|
| 17452337 |
Yu XH et al.:
NPC1, intracellular cholesterol trafficking and atherosclerosis
Clin. Chim. Acta
2014
429: 69-75
|
| 17033625 |
Lorenz-Depiereux B et al. et al.:
DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis
Nat. Genet.
2006
38: 1248-1250
|
| 18923427 |
Petta TB et al.:
Human DNA polymerase iota protects cells against oxidative stress
EMBO J.
2008
27: 2883-2895
|
| 22879941 |
Rangiani A et al.:
Protective roles of DMP1 in high phosphate homeostasis
PLoS ONE
2012
7
|
| 23891004 |
Stehling O et al.:
Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins
Cell Metab.
2013
18: 187-198
|
| 24412312 |
Leeb M et al.:
Genetic exploration of the exit from self-renewal using haploid embryonic stem cells
Cell Stem Cell
2014
14: 385-393
|
| 12815630 |
Smoak IW et al.:
Hyperglycemia-induced TGFbeta and fibronectin expression in embryonic mouse heart
Dev. Dyn.
2004
231: 179-189
|
| 23685977 |
Han GD et al.:
Metabolic energy sensors (AMPK and SIRT1), protein carbonylation and cardiac failure as biomarkers of thermal stress in an intertidal limpet: linking energetic allocation with environmental temperature during aerial emersion
J Exp Biol
2013
216: 3273-3282
|
| 25450523 |
Damiano F et al.:
Expression of citrate carrier gene is activated by ER stress effectors XBP1 and ATF6alpha, binding to an UPRE in its promoter
Biochim. Biophys. Acta
2015
1849: 23-31
|
| 25450523 |
Damiano F et al.:
Expression of citrate carrier gene is activated by ER stress effectors XBP1 and ATF6alpha, binding to an UPRE in its promoter
Biochim Biophys Acta
2015
1849: 23-31
|
| 18586032 |
Ring G et al.:
Transmembrane protein 85 from both human (TMEM85) and yeast (YGL231c) inhibit hydrogen peroxide mediated cell death in yeast
FEBS Lett
2008
582: 2637-2642
|
| 15479637 |
Sampath P et al.:
Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation
Cell
2004
119: 195-208
|
| 20043084 |
Sato K et al.:
FBXL16 is a novel E2F1-regulated gene commonly upregulated in p16INK4A- and p14ARF-silenced HeLa cells
Int. J. Oncol.
2010
36: 479-490
|
| 26860958 |
Zheng N et al.:
Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteins
Int. J. Biochem. Cell Biol.
2016
73: 99-110
|
| 19494553 |
Dockrell ME et al.:
Tgf-beta auto-induction and connective tissue growth factor expression in human renal tubule epithelial cells requires N-ras
Nephron Exp. Nephrol.
2009
112: e71-e79
|
| 26868148 |
Johmura Y et al. et al.:
SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence
Nat Commun
2016
7: 10574
|
| 9325156 |
Jenne DE et al.:
The human guanidinoacetate methyltransferase (GAMT) gene maps to a syntenic region on 19p13.3, homologous to band C of mouse chromosome 10, but GAMT is not mutated in jittery mice
Biochem. Biophys. Res. Commun.
1997
238: 723-727
|
| 31092502 |
Kong JH et al.:
Biochemical mechanisms of vertebrate hedgehog signaling
|
| 17855383 |
Feigin ME et al.:
RGS19 regulates Wnt-beta-catenin signaling through inactivation of Galpha(o)
J Cell Sci
2007
120: 3404-3414
|
| 16303557 |
Liu X et al.:
Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins
Curr Biol
2005
15: 1989-1997
|
| 17350174 |
Jhaveri KA et al.:
Reduced basal and lipopolysaccharide-stimulated adenosine A1 receptor expression in the brain of nuclear factor-kappaB p50-/- mice
Neuroscience
2007
146: 415-426
|
| 22403608 |
Meurs I et al. et al.:
Effects of deletion of macrophage ABCA7 on lipid metabolism and the development of atherosclerosis in the presence and absence of ABCA1
PLoS ONE
2012
7
|
| 27345520 |
Jang CH et al.:
The Role of Lipin-1 in the Regulation of Fibrogenesis and TGF-beta Signaling in Hepatic Stellate Cells
Toxicol. Sci.
2016
153: 28-38
|
| 28505227 |
Alway SE et al.:
Resveratrol Enhances Exercise-Induced Cellular and Functional Adaptations of Skeletal Muscle in Older Men and Women
J. Gerontol. A Biol. Sci. Med. Sci.
2017
72: 1595-1606
|
| 16901463 |
Sevov M et al.:
Resveratrol regulates the expression of LXR-alpha in human macrophages
Biochem. Biophys. Res. Commun.
2006
348: 1047-1054
|
| 29175670 |
von Hardenberg S et al.:
ApoE is a major determinant of hepatic bile acid homeostasis in mice
J. Nutr. Biochem.
2018
52: 82-91
|
| 29669734 |
Schnellmann R et al.:
A Selective Extracellular Matrix Proteomics Approach Identifies Fibronectin Proteolysis by A Disintegrin-like and Metalloprotease Domain with Thrombospondin Type 1 Motifs (ADAMTS16) and Its Impact on Spheroid Morphogenesis
Mol. Cell Proteomics
2018
17: 1410-1425
|
| 23823482 |
author information missing
article information missing
|
| 29939616 |
author information missing
Insulin Resistance }, authors { names ml { Freeman AM, Soman-Faulkner K, Pennings N } }, from book { title { name StatPearls }, authors { names ml { } }, imp { date std { year 2019, month 1 }, language eng, pubstatus ppublish, history { { pubstatus pubmed, date std { year 2018, month 6, day 26, hour 6, minute 1 } }, { pubstatus medline, date std { year 2018, month 6, day 26, hour 6, minute 1 } }, { pubstatus other, date std { year 2018, month 6, day 26, hour 6, minute 1 } } } } }, ids { pubmed 29939616 } }, abstract Insulin resistance is identified as an impaired biologic response to insulin stimulation of target tissues, primarily liver, muscle, and adipose tissue. Insulin resistance impairs glucose disposal, resulting in a compensatory increase in beta-cell insulin production and hyperinsulinemia. [1][2][3]The metabolic consequences of insulin resistance can result in hyperglycemia, hypertension, dyslipidemia, visceral adiposity, hyperuricemia, elevated inflammatory markers, endothelial dysfunction, and a prothrombic state. Progression of insulin resistance can lead to metabolic syndrome, nonalcoholic fatty liver disease (NAFLD), and type 2 diabetes mellitus. Insulin resistance is primarily an acquired condition related to excess body fat, though genetic causes are identified as well. The clinical definition of insulin resistance remains elusive as there is not a generally accepted test for insulin resistance. [4][5]Clinically, insulin resistance is recognized via the metabolic consequences associated with insulin resistance as described in metabolic syndrome and insulin resistance syndrome. The gold standard for measurement of insulin resistance is the hyperinsulinemic-euglycemic glucose clamp technique. This is a research technique with limited clinical applicability; however, there are a number of clinically useful surrogate measures of insulin resistance, including HOMA-IR, HOMA2, QUICKI, serum triglyceride and triglyceride/HDL ratio. In addition, several measures assess insulin resistance based on a serum glucose and/or insulin response to a glucose challenge. The predominate consequence of insulin resistance is type 2 diabetes (T2DM). Insulin resistance is thought to precede the development of T2DM by 10 to 15 years. The development of insulin resistance typically results in a compensatory increase in endogenous insulin production. Elevated levels of endogenous insulin, an anabolic hormone, is associated with insulin resistance and results in weight gain which, in turn, exacerbates insulin resistance.[6][7] This vicious cycle continues until pancreatic beta cell activity can no longer adequately meet the insulin demand created by insulin resistance, resulting in hyperglycemia. With continued mismatch between insulin demand and insulin production, glycemic levels rise to levels consistent with T2DM. Resistance to exogenous insulin has also been described. An arbitrary but clinically useful benchmark considers patients requiring greater than 1 unit/kilogram/day of exogenous insulin to maintain glycemic control insulin resistant. Patients requiring greater than 200 units of exogenous insulin per day are considered severely insulin resistant. In addition to T2DM, the spectrum of disease associated with insulin resistance includes obesity, cardiovascular disease, nonalcoholic fatty liver disease, metabolic syndrome, and polycystic ovary syndrome(PCOS). These are all of great consequence in the United States with a tremendous burden being placed on the healthcare system to treat the direct and indirect conditions associated with insulin resistance. The microvascular complications of diabetes (neuropathy, retinopathy, and nephropathy), as well as the associated macrovascular complications (coronary artery disease [CAD], cerebral-vascular disease, and peripheral artery disease [PAD]), consume the lions share of the healthcare dollar. Lifestyle modification should be the primary focus for the treatment of insulin resistance. Nutritional intervention with calorie reduction and avoidance of carbohydrates that stimulate excessive insulin demand are a cornerstone to treatment. Physical activity helps to increase energy expenditure and improve muscle insulin sensitivity. Medications also can improve insulin response and reduce insulin demand
|
| 10320052 |
Hotamisligil GS et al.:
Mechanisms of TNF-alpha-induced insulin resistance
Exp. Clin. Endocrinol. Diabetes
1999
107: 119-125
|
| 18351672 |
McGlinn E et al.:
Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb
Dev Dyn
2008
237: 1172-1182
|
| 14739301 |
Zilberberg A et al.:
The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway
J. Biol. Chem.
2004
279
|
| 26050734 |
Kowal JM et al.:
Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells
Cell Commun. Signal
2015
13: 28
|
| 29901078 |
Liu Y et al.:
Farnesoid X receptor agonist decreases lipid accumulation by promoting hepatic fatty acid oxidation in db/db mice
Int. J. Mol. Med.
2018
42: 1723-1731
|
| 26042593 |
Csak T et al.:
MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis
PLoS ONE
2015
10
|
| 30998645 |
Sun S et al. et al.:
Tudca Ameliorates Liver Injury Via Activation of SIRT1-FXR Signaling in a Rat Hemorrhagic Shock Model
|
| 3977877 |
author information missing
Carnitine acyltransferase activities in rat brain mitochondria. Bimodal distribution, kinetic constants, regulation by malonyl-CoA and developmental pattern
Biochem. J.
1985
226: 323-330
|
| 15135048 |
Szymkiewicz I et al.:
SH3P2 in complex with Cbl and Src
FEBS Lett.
2004
565: 33-38
|
| 21666256 |
Rorbach J et al.:
PDE12 removes mitochondrial RNA poly(A) tails and controls translation in human mitochondria
Nucleic Acids Res.
2011
39: 7750-7763
|
| 10772957 |
IJlst L et al.:
Molecular cloning and expression of human L-pipecolate oxidase
Biochem. Biophys. Res. Commun.
2000
270: 1101-1105
|
| 21900944 |
Shen H et al.:
Genome-wide association study identifies genetic variants in GOT1 determining serum aspartate aminotransferase levels
J. Hum. Genet.
2011
56: 801-805
|
| 12576545 |
Zheng B et al.:
GDE1/MIR16 is a glycerophosphoinositol phosphodiesterase regulated by stimulation of G protein-coupled receptors
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 1745-1750
|
| 28843504 |
Hussain Z et al.:
Mammalian enzymes responsible for the biosynthesis of N-acylethanolamines
Biochim Biophys Acta Mol Cell Biol Lipids
2017
1862: 1546-1561
|
| 16006554 |
Thoden JB et al.:
The molecular architecture of human N-acetylgalactosamine kinase
J. Biol. Chem.
2005
280
|
| 28654657 |
Termini JM et al.:
HEK293T cell lines defective for O-linked glycosylation
PLoS ONE
2017
12
|
| 31264387 |
Ferreira-Junior NC et al.:
Exercise training increases GAD65 expression, restores the depressed GABAA receptor function within the PVN and reduces sympathetic modulation in hypertension
Physiol Rep
2019
7
|
| 23028330 |
Swaminathan G et al.:
A role for microRNA-155 modulation in the anti-HIV-1 effects of Toll-like receptor 3 stimulation in macrophages
PLoS Pathog.
2012
8
|
| 29932989 |
Singh K et al.:
NLRX1 resides in mitochondrial RNA granules and regulates mitochondrial RNA processing and bioenergetic adaptation
Biochim Biophys Acta Mol Cell Res
2018
1865: 1260-1276
|
| 21775430 |
author information missing
article information missing
|
| 29036396 |
Jourdain AA et al.:
The FASTK family of proteins: emerging regulators of mitochondrial RNA biology
Nucleic Acids Res.
2017
45
|
| 23844030 |
Xie L et al.:
Exocyst sec5 regulates exocytosis of newcomer insulin granules underlying biphasic insulin secretion
PLoS ONE
2013
8
|
| 18799622 |
Xu L et al.:
An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex
Mol. Biol. Cell
2008
19: 5059-5071
|
| 18353293 |
Smith RD et al.:
Role of the conserved oligomeric Golgi (COG) complex in protein glycosylation
Carbohydr. Res.
2008
343: 2024-2031
|
| 21868385 |
Seok HY et al.:
miR-155 inhibits expression of the MEF2A protein to repress skeletal muscle differentiation
J. Biol. Chem.
2011
286
|
| 9405631 |
Kee Y et al.:
Subunit structure of the mammalian exocyst complex
Proc. Natl. Acad. Sci. U.S.A.
1997
94
|
| 25396269 |
Saternus R et al.:
A closer look at evolution: Variants (SNPs) of genes involved in skin pigmentation, including EXOC2, TYR, TYRP1, and DCT, are associated with 25(OH)D serum concentration
Endocrinology
2015
156: 39-47
|
| 27354378 |
Bruno J et al.:
SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes
J. Cell Biol.
2016
214: 61-76
|
| 24321552 |
Park UH et al.:
Reciprocal regulation of LXRalpha activity by ASXL1 and ASXL2 in lipogenesis
Biochem. Biophys. Res. Commun.
2014
443: 489-494
|
| 20576682 |
Babbey CM et al.:
Rab10 associates with primary cilia and the exocyst complex in renal epithelial cells
Am. J. Physiol. Renal Physiol.
2010
299: F495-F506
|
| 28428248 |
Saint-Pol J et al.:
New insights into the tetraspanin Tspan5 using novel monoclonal antibodies
J. Biol. Chem.
2017
292: 9551-9566
|
| 27004216 |
Suresh PS et al.:
In silico analysis of polymorphisms in microRNAs that target genes affecting aerobic glycolysis
Ann Transl Med
2016
4: 69
|
| 31193288 |
Khanna M et al.:
Data highlighting miR-155 and GAPDH correlation
Data Brief
2019
24
|
| 25380825 |
Bojjireddy N et al.:
EFR3s are palmitoylated plasma membrane proteins that control responsiveness to G-protein-coupled receptors
J. Cell. Sci.
2015
128: 118-128
|
| 20603073 |
Smogorzewska A et al.:
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair
Mol. Cell
2010
39: 36-47
|
| 28074080 |
Thoudam T et al.:
Role of Mitochondria-Associated Endoplasmic Reticulum Membrane in Inflammation-Mediated Metabolic Diseases
Mediators Inflamm.
2016
2016
|
| 30038017 |
Kincaid RP et al.:
RNA triphosphatase DUSP11 enables exonuclease XRN-mediated restriction of hepatitis C virus
Proc. Natl. Acad. Sci. U.S.A.
2018
115: 8197-8202
|
| 19120688 |
Caprara G et al.:
Isolation and characterization of DUSP11, a novel p53 target gene
J Cell Mol Med
2009
13: 2158-2170
|
| 10428034 |
Yang Y et al.:
Integrators of the cytoskeleton that stabilize microtubules
Cell
1999
98: 229-238
|
| 11375975 |
Favre B et al.:
The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of multiple alternative splice variants of ERBIN and analysis of their tissue expression
J. Biol. Chem.
2001
276
|
| 14581450 |
Liu JJ et al.:
BPAG1n4 is essential for retrograde axonal transport in sensory neurons
J. Cell Biol.
2003
163: 223-229
|
| 20164846 |
Groves RW et al. et al.:
A homozygous nonsense mutation within the dystonin gene coding for the coiled-coil domain of the epithelial isoform of BPAG1 underlies a new subtype of autosomal recessive epidermolysis bullosa simplex
J. Invest. Dermatol.
2010
130: 1551-1557
|
| 27848932 |
Damiani D et al.:
Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors
Nat Commun
2016
7: 13509
|
| 12522690 |
Xu J et al.:
Identification of a novel human DDX40gene, a new member of the DEAH-box protein family
J. Hum. Genet.
2002
47: 681-683
|
| 25712129 |
Ng CK et al.:
Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects
Hum. Mol. Genet.
2015
24: 3163-3171
|
| 26001796 |
Zhou M et al.:
DcpS is a transcript-specific modulator of RNA in mammalian cells
RNA
2015
21: 1306-1312
|
| 14660610 |
Chuang SS et al.:
CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids
J. Biol. Chem.
2004
279: 6305-6314
|
| 16549446 |
Kemmis CM et al.:
Human mammary epithelial cells express CYP27B1 and are growth inhibited by 25-hydroxyvitamin D-3, the major circulating form of vitamin D-3
J. Nutr.
2006
136: 887-892
|
| 27272971 |
Sala-Vila A et al. et al.:
Interplay between hepatic mitochondria-associated membranes, lipid metabolism and caveolin-1 in mice
Sci Rep
2016
6: 27351
|
| 9326943 |
Geller DH et al.:
The genetic and functional basis of isolated 17,20-lyase deficiency
Nat. Genet.
1997
17: 201-205
|
| 14671162 |
Martin RM et al.:
P450c17 deficiency in Brazilian patients: biochemical diagnosis through progesterone levels confirmed by CYP17 genotyping
J. Clin. Endocrinol. Metab.
2003
88: 5739-5746
|
| 9452426 |
Auchus RJ et al.:
Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer
J. Biol. Chem.
1998
273: 3158-3165
|
| 15107842 |
Wu X et al.:
Mutation of the COG complex subunit gene COG7 causes a lethal congenital disorder
Nat. Med.
2004
10: 518-523
|
| 18408006 |
Huysamen C et al.:
CLEC9A is a novel activation C-type lectin-like receptor expressed on BDCA3+ dendritic cells and a subset of monocytes
J. Biol. Chem.
2008
283
|
| 28630144 |
Yu-Kemp HC et al.:
CRMP-1 enhances EVL-mediated actin elongation to build lamellipodia and the actin cortex
J. Cell Biol.
2017
216: 2463-2479
|
| 24322428 |
Tang VW et al.:
FSGS3/CD2AP is a barbed-end capping protein that stabilizes actin and strengthens adherens junctions
J. Cell Biol.
2013
203: 815-833
|
| 20639531 |
Takaku M et al.:
Single-stranded DNA catenation mediated by human EVL and a type I topoisomerase
Nucleic Acids Res.
2010
38: 7579-7586
|
| 23112755 |
Cordova-Fletes C et al.:
A de novo sSMC(22) Characterized by High-Resolution Arrays in a Girl with Cat-Eye Syndrome without Coloboma
Mol Syndromol
2012
3: 131-135
|
| 15640247 |
Banting GS et al.:
CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L
Hum. Mol. Genet.
2005
14: 513-524
|
| 22946059 |
Tian Y et al.:
Anoctamins are a family of Ca2+-activated Cl- channels
J. Cell. Sci.
2012
125: 4991-4998
|
| 11431032 |
Marinissen MJ et al.:
G-protein-coupled receptors and signaling networks: emerging paradigms
Trends Pharmacol. Sci.
2001
22: 368-376
|
| 10373416 |
Yamazaki T et al.:
CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cells
J. Biol. Chem.
1999
274
|
| 9426281 |
Whitehead CM et al.:
ASE-1: a novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes
Chromosoma
1997
106: 493-502
|
| 19144519 |
Hayashi T et al.:
MAM: more than just a housekeeper
Trends Cell Biol.
2009
19: 81-88
|
| 17024184 |
Shibue T et al.:
Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathways
EMBO J.
2006
25: 4952-4962
|
| 11463392 |
Nakano K et al.:
PUMA, a novel proapoptotic gene, is induced by p53
Mol. Cell
2001
7: 683-694
|
| 23840669 |
Cross BM et al.:
SPCA2 regulates Orai1 trafficking and store independent Ca2+ entry in a model of lactation
PLoS ONE
2013
8
|
| 31076498 |
Dang DK et al.:
A Ca(2+)-ATPase Regulates E-cadherin Biogenesis and Epithelial-Mesenchymal Transition in Breast Cancer Cells
Mol. Cancer Res.
2019
17: 1735-1747
|
| 29144457 |
Brickner JR et al. et al.:
A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair
Nature
2017
551: 389-393
|
| 20663892 |
Tong F et al.:
Decreased expression of ARV1 results in cholesterol retention in the endoplasmic reticulum and abnormal bile acid metabolism
J. Biol. Chem.
2010
285
|
| 25589784 |
Ousingsawat J et al.:
Anoctamin-6 controls bone mineralization by activating the calcium transporter NCX1
J. Biol. Chem.
2015
290: 6270-6280
|
| 8598869 |
Hurst JA et al.:
A syndrome of mental retardation, short stature, hemolytic anemia, delayed puberty, and abnormal facial appearance: similarities to a report of aldolase A deficiency
Am. J. Med. Genet.
1987
28: 965-970
|
| 7503984 |
Hoops TC et al.:
Incorporation of the pancreatic membrane protein GP-2 into secretory granules in exocrine but not endocrine cells
J. Biol. Chem.
1993
268
|
| 17967891 |
Myant K et al.:
LSH cooperates with DNA methyltransferases to repress transcription
Mol. Cell. Biol.
2008
28: 215-226
|
| 23137319 |
Susanto O et al.:
Controversies in granzyme biology
Tissue Antigens
2012
80: 477-487
|
| 10966646 |
Waugh SM et al.:
The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity
Nat. Struct. Biol.
2000
7: 762-765
|
| 11790262 |
Trapani JA et al.:
Granzymes: a family of lymphocyte granule serine proteases
Genome Biol.
2001
2: REVIEWS3014
|
| 7686381 |
Bezprozvanny I et al.:
ATP modulates the function of inositol 1,4,5-trisphosphate-gated channels at two sites
Neuron
1993
10: 1175-1184
|
| 32024968 |
NavaneethaKrishnan S et al.:
mPTP opening caused by Cdk5 loss is due to increased mitochondrial Ca(2+) uptake
Oncogene
2020
39: 2797-2806
|
| 23798435 |
Buchmayer F et al. et al.:
Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate
Proc. Natl. Acad. Sci. U.S.A.
2013
110
|
| 28325789 |
Khalifa AR et al.:
Sex-specific differences in mitochondria biogenesis, morphology, respiratory function, and ROS homeostasis in young mouse heart and brain
|
| 20651247 |
Siskova Z et al.:
Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease
Am. J. Pathol.
2010
177: 1411-1421
|
| 20368174 |
Matsuo H et al. et al.:
Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population
Sci Transl Med
2009
1: 5ra11
|
| 17145775 |
van Herwaarden AE et al.:
Multidrug transporter ABCG2/breast cancer resistance protein secretes riboflavin (vitamin B2) into milk
Mol. Cell. Biol.
2007
27: 1247-1253
|
| 23954234 |
Lin YH et al.:
Protoporphyrin IX accumulation disrupts mitochondrial dynamics and function in ABCG2-deficient hepatocytes
FEBS Lett.
2013
587: 3202-3209
|
| 20085746 |
Schonfeld P et al.:
Mitochondrial fatty acid oxidation and oxidative stress: lack of reverse electron transfer-associated production of reactive oxygen species
Biochim. Biophys. Acta
2010
1797: 929-938
|
| 12429862 |
Jonker JW et al.:
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
Proc. Natl. Acad. Sci. U.S.A.
2002
99
|
| 26701913 |
Lin DT et al.:
ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization
Elife
2015
4
|
| 27307232 |
Yokoi N et al.:
Identification of PSD-95 Depalmitoylating Enzymes
J. Neurosci.
2016
36: 6431-6444
|
| 19797056 |
Eggers CT et al.:
D-AKAP2 interacts with Rab4 and Rab11 through its RGS domains and regulates transferrin receptor recycling
J. Biol. Chem.
2009
284
|
| 12802337 |
Yamauchi T et al. et al.:
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
Nature
2003
423: 762-769
|
| 18352857 |
Canales J et al.:
Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells
Biochem. J.
2008
413: 103-113
|
| 17412687 |
Xu J et al.:
XB130, a novel adaptor protein for signal transduction
J. Biol. Chem.
2007
282
|
| 29343764 |
Jiang X et al. et al.:
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
Nat Commun
2018
9: 260
|
| 29995852 |
Kanarek N et al.:
Histidine catabolism is a major determinant of methotrexate sensitivity
Nature
2018
559: 632-636
|
| 22056818 |
Peltola MA et al.:
AMIGO is an auxiliary subunit of the Kv2.1 potassium channel
EMBO Rep.
2011
12: 1293-1299
|
| 22284051 |
Zhang J et al.:
Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function
Traffic
2012
13: 745-757
|
| 23098614 |
Lee J et al.:
Metabolomic profiling reveals a role for CPT1c in neuronal oxidative metabolism
BMC Biochem.
2012
13: 23
|
| 9373137 |
Begley DA et al.:
Identification and sequence of human PKY, a putative kinase with increased expression in multidrug-resistant cells, with homology to yeast protein kinase Yak1
Gene
1997
200: 35-43
|
| 25845660 |
Ludzki A et al.:
Rapid Repression of ADP Transport by Palmitoyl-CoA Is Attenuated by Exercise Training in Humans: A Potential Mechanism to Decrease Oxidative Stress and Improve Skeletal Muscle Insulin Signaling
Diabetes
2015
64: 2769-2779
|
| 24285859 |
Hamilton AJ et al. et al.:
The HNF4A R76W mutation causes atypical dominant Fanconi syndrome in addition to a beta cell phenotype
J Med Genet
2014
51: 165-169
|
| 29558740 |
Guardia CM et al.:
Neuronal functions of adaptor complexes involved in protein sorting
Curr. Opin. Neurobiol.
2018
51: 103-110
|
| 12297508 |
Lee SF et al.:
Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch
J. Biol. Chem.
2002
277
|
| 12724404 |
Fleischer TC et al.:
Identification and characterization of three new components of the mSin3A corepressor complex
Mol. Cell. Biol.
2003
23: 3456-3467
|
| 23487765 |
Wu RC et al.:
ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways
Proc. Natl. Acad. Sci. U.S.A.
2013
110: 4616-4621
|
| 17043311 |
Wu MY et al.:
Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain
Genes Dev.
2006
20: 2859-2870
|
| 31775868 |
Cao X et al.:
Angiotensin-converting enzyme 2 regulates endoplasmic reticulum stress and mitochondrial function to preserve skeletal muscle lipid metabolism
Lipids Health Dis
2019
18: 207
|
| 29128354 |
Shi TT et al.:
Angiotensin-converting enzyme 2 regulates mitochondrial function in pancreatic beta-cells
Biochem. Biophys. Res. Commun.
2018
495: 860-866
|
| 16537643 |
Hofmann I et al.:
An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility
J. Cell. Sci.
2006
119: 1494-1503
|
| 12087134 |
Kellenberger S et al.:
Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure
Physiol. Rev.
2002
82: 735-767
|
| 24632142 |
Wang Q et al.:
Reexamination of aspartoacylase: is this human enzyme really a glycoprotein?
Arch. Biochem. Biophys.
2014
548: 66-73
|
| 12473658 |
Scherz-Shouval R et al.:
The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A
J. Biol. Chem.
2003
278
|
| 22441018 |
Betin VM et al.:
A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress
Autophagy
2012
8: 664-676
|
| 18752060 |
Smith AN et al.:
The d subunit plays a central role in human vacuolar H(+)-ATPases
J. Bioenerg. Biomembr.
2008
40: 371-380
|
| 21844891 |
Chen Y et al.:
A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo
Cell Res.
2012
22: 333-345
|
| 30947313 |
Naik J et al. et al.:
The P4-ATPase ATP9A is a novel determinant of exosome release
PLoS ONE
2019
14
|
| 30213940 |
McGough IJ et al.:
SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion
Nat Commun
2018
9: 3737
|
| 26240149 |
Ansari IU et al.:
Characterization of P4 ATPase Phospholipid Translocases (Flippases) in Human and Rat Pancreatic Beta Cells: THEIR GENE SILENCING INHIBITS INSULIN SECRETION
J. Biol. Chem.
2015
290
|
| 27733620 |
Tanaka Y et al.:
The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane
Mol. Biol. Cell
2016
27: 3883-3893
|
| 26094765 |
Teranishi Y et al.:
Proton myo-inositol cotransporter is a novel gamma-secretase associated protein that regulates Abeta production without affecting Notch cleavage
FEBS J.
2015
282: 3438-3451
|
| 12204112 |
Hoshino H et al.:
Expression of the oxidative stress-regulated transcription factor bach2 in differentiating neuronal cells
J. Biochem.
2002
132: 427-431
|
| 17991429 |
Hong SW et al.:
The role of Bach2 in nucleic acid-triggered antiviral innate immune responses
Biochem. Biophys. Res. Commun.
2008
365: 426-432
|
| 21743456 |
Pykalainen A et al. et al.:
Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures
Nat. Struct. Mol. Biol.
2011
18: 902-907
|
| 28394342 |
Huhn SC et al.:
Regulation of spindle integrity and mitotic fidelity by BCCIP
Oncogene
2017
36: 4750-4766
|
| 18440304 |
Ash SC et al.:
LYRIC/AEG-1 overexpression modulates BCCIPalpha protein levels in prostate tumor cells
Biochem. Biophys. Res. Commun.
2008
371: 333-338
|
| 10878006 |
Ono T et al.:
TOK-1, a novel p21Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase
J. Biol. Chem.
2000
275
|
| 17947333 |
Lu H et al.:
BCCIP regulates homologous recombination by distinct domains and suppresses spontaneous DNA damage
Nucleic Acids Res.
2007
35: 7160-7170
|
| 10620517 |
Cunningham O et al.:
Initial-rate kinetics of the flavin reductase reaction catalysed by human biliverdin-IXbeta reductase (BVR-B)
Biochem. J.
2000
345: Pt 2 393-399
|
| 8280170 |
Yamaguchi T et al.:
Complete amino acid sequence of biliverdin-IX beta reductase from human liver
Biochem. Biophys. Res. Commun.
1993
197: 1518-1523
|
| 24360279 |
Liu W et al.:
Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release
Cell
2013
155: 1581-1595
|
| 27784631 |
Malik U et al.:
Structural and functional annotation of human FAM26F: A multifaceted protein having a critical role in the immune system
Gene
2017
597: 66-75
|
| 19422456 |
Varga-Szabo D et al.:
Calcium signaling in platelets
J. Thromb. Haemost.
2009
7: 1057-1066
|
| 19889881 |
Kaneiwa T et al.:
Identification of human hyaluronidase-4 as a novel chondroitin sulfate hydrolase that preferentially cleaves the galactosaminidic linkage in the trisulfated tetrasaccharide sequence
Glycobiology
2010
20: 300-309
|
| 10571240 |
D'Arcangelo G et al.:
Reelin is a ligand for lipoprotein receptors
Neuron
1999
24: 471-479
|
| 10373494 |
Yamin R et al.:
Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimers amyloid-beta peptide degradation
J. Biol. Chem.
1999
274
|
| 22514144 |
Kaden D et al. et al.:
Novel APP/Abeta mutation K16N produces highly toxic heteromeric Abeta oligomers
EMBO Mol Med
2012
4: 647-659
|
| 15655771 |
Esper F et al.:
Association between a novel human coronavirus and Kawasaki disease
J. Infect. Dis.
2005
191: 499-502
|
| 18682402 |
Choi WI et al.:
Proto-oncogene FBI-1 (Pokemon) and SREBP-1 synergistically activate transcription of fatty-acid synthase gene (FASN)
J. Biol. Chem.
2008
283
|
| 32256356 |
Dorotea D et al.:
Recent Insights Into SREBP as a Direct Mediator of Kidney Fibrosis via Lipid-Independent Pathways
Front Pharmacol
2020
11: 265
|
| 12372844 |
Shrimpton CN et al.:
Soluble metalloendopeptidases and neuroendocrine signaling
Endocr. Rev.
2002
23: 647-664
|
| 12456642 |
Castellani V et al.:
Cis and trans interactions of L1 with neuropilin-1 control axonal responses to semaphorin 3A
EMBO J.
2002
21: 6348-6357
|
| 15037590 |
Chaerkady R et al.:
Characterization of a bradykinin-hydrolyzing protease from the bovine lens
Invest. Ophthalmol. Vis. Sci.
2004
45: 1214-1223
|
| 23104057 |
Janssen BJ et al.:
Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex
Nat. Struct. Mol. Biol.
2012
19: 1293-1299
|
| 25320080 |
Keire PA et al.:
A role for versican in the development of leiomyosarcoma
J. Biol. Chem.
2014
289
|
| 25921289 |
Emdal KB et al.:
Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation
Sci Signal
2015
8: ra40
|
| 11815627 |
Vickers C et al. et al.:
Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
J Biol Chem
2002
277
|
| 26586662 |
Kiene LS et al. et al.:
Deletion of Hyaluronan Synthase 3 Inhibits Neointimal Hyperplasia in Mice
Arterioscler. Thromb. Vasc. Biol.
2016
36: e9-16
|
| 32001344 |
Harten IA et al. et al.:
The synthesis and secretion of versican isoform V3 by mammalian cells: A role for N-linked glycosylation
|
| 26448752 |
Sherman LS et al.:
Hyaluronan Synthesis, Catabolism, and Signaling in Neurodegenerative Diseases
Int J Cell Biol
2015
2015
|
| 14559994 |
Lee AH et al.:
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
Mol. Cell. Biol.
2003
23: 7448-7459
|
| 26200341 |
Zhao L et al. et al.:
Lanosterol reverses protein aggregation in cataracts
Nature
2015
523: 607-611
|
| 24691700 |
Tian T et al.:
A low prevalence of sarcomeric gene variants in a Chinese cohort with left ventricular non-compaction
Heart Vessels
2015
30: 258-264
|
| 25559421 |
Sanford M et al.:
Simeprevir: a review of its use in patients with chronic hepatitis C virus infection
Drugs
2015
75: 183-196
|
| 32320852 |
Ekins S et al.:
Deja vu: Stimulating open drug discovery for SARS-CoV-2
|
| 32280433 |
Beck BR et al.:
Predicting commercially available antiviral drugs that may act on the novel coronavirus (SARS-CoV-2) through a drug-target interaction deep learning model
Comput Struct Biotechnol J
2020
18: 784-790
|
| 24644279 |
Rappe U et al.:
Nuclear ARVCF protein binds splicing factors and contributes to the regulation of alternative splicing
J. Biol. Chem.
2014
289
|
| 15456900 |
Kausalya PJ et al.:
Association of ARVCF with zonula occludens (ZO)-1 and ZO-2: binding to PDZ-domain proteins and cell-cell adhesion regulate plasma membrane and nuclear localization of ARVCF
Mol. Biol. Cell
2004
15: 5503-5515
|
| 10725230 |
Mariner DJ et al.:
ARVCF localizes to the nucleus and adherens junction and is mutually exclusive with p120(ctn) in E-cadherin complexes
J. Cell. Sci.
2000
113: ( Pt 8
|
| 29509190 |
Giurato G et al.:
Quantitative mapping of RNA-mediated nuclear estrogen receptor beta interactome in human breast cancer cells
Sci Data
2018
5
|
| 29980799 |
Ungewiss H et al.:
Dsg2 via Src-mediated transactivation shapes EGFR signaling towards cell adhesion
Cell. Mol. Life Sci.
2018
75: 4251-4268
|
| 27417273 |
Dorland YL et al. et al.:
The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions
Nat Commun
2016
7: 12210
|
| 11058098 |
Kaufmann U et al.:
The armadillo repeat region targets ARVCF to cadherin-based cellular junctions
J. Cell. Sci.
2000
113: ( Pt 22
|
| 11736639 |
Ivanov DB et al.:
Structure and functions of classical cadherins
Biochemistry Mosc.
2001
66: 1174-1186
|
| 9788273 |
Spiryda LB et al.:
Myelin protein zero and membrane adhesion
J. Neurosci. Res.
1998
54: 137-146
|
| 20608934 |
Ye L et al.:
Bone morphogenetic protein-10 (BMP-10) inhibits aggressiveness of breast cancer cells and correlates with poor prognosis in breast cancer
Cancer Sci.
2010
101: 2137-2144
|
| 22765916 |
Redies C et al.:
Cadherins and neuropsychiatric disorders
Brain Res.
2012
1470: 130-144
|
| 16427635 |
Lee NP et al.:
Kidney claudin-19: localization in distal tubules and collecting ducts and dysregulation in polycystic renal disease
FEBS Lett.
2006
580: 923-931
|
| 8108413 |
Connelly MA et al.:
PANG, a gene encoding a neuronal glycoprotein, is ectopically activated by intracisternal A-type particle long terminal repeats in murine plasmacytomas
Proc. Natl. Acad. Sci. U.S.A.
1994
91: 1337-1341
|
| 8630060 |
Kajiwara K et al.:
Cloning of SEZ-12 encoding seizure-related and membrane-bound adhesion protein
Biochem. Biophys. Res. Commun.
1996
222: 144-148
|
| 30604460 |
Cao X et al.:
Angiotensin-converting enzyme 2 inhibits endoplasmic reticulum stress-associated pathway to preserve nonalcoholic fatty liver disease
Diabetes Metab. Res. Rev.
2019
35: e3123
|
| 32402856 |
Grimm C et al.:
Could an endo-lysosomal ion channel be the Achilles heel of SARS-CoV2?
Cell Calcium
2020
88
|
| 25126162 |
Fang M et al.:
Camk2b protects neurons from homocysteine-induced apoptosis with the involvement of HIF-1alpha signal pathway
Int J Clin Exp Med
2014
7: 1659-1668
|
| 19206230 |
Maresca A et al.:
Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors
J. Am. Chem. Soc.
2009
131: 3057-3062
|
| 29622847 |
Oo PS et al.:
Estrogen Regulates Mitochondrial Morphology through Phosphorylation of Dynamin-related Protein 1 in MCF7 Human Breast Cancer Cells
Acta Histochem Cytochem
2018
51: 21-31
|
| 31915205 |
Carayol J et al.:
Genetic Susceptibility Determines beta-Cell Function and Fasting Glycemia Trajectories Throughout Childhood: A 12-Year Cohort Study (EarlyBird 76)
Diabetes Care
2020
43: 653-660
|
| 26239056 |
Vierra NC et al.:
Type 2 Diabetes-Associated K+ Channel TALK-1 Modulates beta-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis
Diabetes
2015
64: 3818-3828
|
| 31932720 |
Dubey R et al.:
Lipid droplets can promote drug accumulation and activation
Nat. Chem. Biol.
2020
16: 206-213
|
| 1310484 |
Santos RA et al.:
Production of angiotensin-(1-7) by human vascular endothelium
Hypertension
1992
19: II56-II61
|
| 29491369 |
Bernard-Marissal N et al.:
Endoplasmic reticulum and mitochondria in diseases of motor and sensory neurons: a broken relationship?
Cell Death Dis
2018
9: 333
|
| 21685886 |
Baughman JM et al.:
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
Nature
2011
476: 341-345
|
| 24560927 |
Patron M et al.:
MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity
Mol. Cell
2014
53: 726-737
|
| 26968367 |
Mammucari C et al.:
Molecular structure and pathophysiological roles of the Mitochondrial Calcium Uniporter
Biochim. Biophys. Acta
2016
1863: 2457-2464
|
| 24231807 |
Sancak Y et al. et al.:
EMRE is an essential component of the mitochondrial calcium uniporter complex
Science
2013
342: 1379-1382
|
| 25704011 |
Hayashi T et al.:
Sigma-1 receptor: the novel intracellular target of neuropsychotherapeutic drugs
J. Pharmacol. Sci.
2015
127: 2-5
|
| 19052620 |
de Brito OM et al.:
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
Nature
2008
456: 605-610
|
| 22511781 |
Ngoh GA et al.:
Loss of mitofusin 2 promotes endoplasmic reticulum stress
J. Biol. Chem.
2012
287
|
| 9388233 |
Lievremont JP et al.:
BiP, a major chaperone protein of the endoplasmic reticulum lumen, plays a direct and important role in the storage of the rapidly exchanging pool of Ca2+
J. Biol. Chem.
1997
272
|
| 28132811 |
Gomez-Suaga P et al.:
The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy
Curr. Biol.
2017
27: 371-385
|
| 15692567 |
Simmen T et al.:
PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis
EMBO J.
2005
24: 717-729
|
| 21962509 |
Zhu H et al. et al.:
The Lin28/let-7 axis regulates glucose metabolism
Cell
2011
147: 81-94
|
| 21183955 |
Iwasawa R et al.:
Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction
EMBO J.
2011
30: 556-568
|
| 32533648 |
Jameson SA et al.:
Elastin homeostasis is altered with pelvic organ prolapse in cultures of vaginal cells from a lysyl oxidase-like 1 knockout mouse model
Physiol Rep
2020
8
|
| 26997634 |
Sharma S et al.:
Biological effect of LOXL1 coding variants associated with pseudoexfoliation syndrome
Exp. Eye Res.
2016
146: 212-223
|
| 21720385 |
De Stefani D et al.:
VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria
Cell Death Differ.
2012
19: 267-273
|
| 30590033 |
D'Eletto M et al. et al.:
Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75
Cell Rep
2018
25: 3573-3581.e4
|
| 26108729 |
Dombernowsky SL et al. et al.:
The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17
Nat Commun
2015
6: 7518
|
| 28476937 |
Thomas G et al.:
Caught in the act - protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease
J. Cell. Sci.
2017
130: 1865-1876
|
| 28275724 |
Prasad M et al.:
Mitochondrial metabolic regulation by GRP78
Sci Adv
2017
3
|
| 30978349 |
Ibrahim IM et al.:
GRP78: A cells response to stress
Life Sci.
2019
226: 156-163
|
| 24516643 |
Misra UK et al.:
Activated alpha2-macroglobulin binding to cell surface GRP78 induces T-loop phosphorylation of Akt1 by PDK1 in association with Raptor
PLoS ONE
2014
9
|
| 17981125 |
Hayashi T et al.:
Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival
Cell
2007
131: 596-610
|
| 23077600 |
Du Y et al.:
The essential role of Mbd5 in the regulation of somatic growth and glucose homeostasis in mice
PLoS ONE
2012
7
|
| 31218958 |
Zhu J et al.:
Magnesium-dependent Phosphatase (MDP) 1 is a Potential Suppressor of Gastric Cancer
Curr Cancer Drug Targets
2019
19: 817-827
|
| 29866655 |
Kobayashi M et al. et al.:
The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis
|
| 29895827 |
Hitzel J et al. et al.:
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells
Nat Commun
2018
9: 2292
|
| 30309776 |
Gerlini R et al. et al.:
Glucose tolerance and insulin sensitivity define adipocyte transcriptional programs in human obesity
Mol Metab
2018
18: 42-50
|
| 22880006 |
Chafe SC et al.:
Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation
PLoS ONE
2012
7
|
| 18280677 |
Becher JC et al.:
Apolipoprotein E e4 and its prevalence in early childhood death due to sudden infant death syndrome or to recognised causes
Early Hum. Dev.
2008
84: 549-554
|
| 28918391 |
Terrell TR et al.:
Genetic polymorphisms associated with the risk of concussion in 1056 college athletes: a multicentre prospective cohort study
Br J Sports Med
2018
52: 192-198
|
| 31319081 |
Burgos J et al.:
Kir7.1 inwardly rectifying K(+) channel is expressed in ciliary body non pigment epithelial cells and might contribute to intraocular pressure regulation
Exp. Eye Res.
2019
186
|
| 24453077 |
Pottala JV et al.:
Higher RBC EPA + DHA corresponds with larger total brain and hippocampal volumes: WHIMS-MRI study
Neurology
2014
82: 435-442
|
| 27408157 |
Nandy PR et al.:
Male Andropause : A Myth or Reality
Med J Armed Forces India
2008
64: 244-249
|
| 10924412 |
Gould DC et al.:
The male menopause: does it exist?: for: some men need investigation and testosterone treatment }, authors { names std { { name ml Gould DC, affil str Goldcross Medical Services, 20 Harmount House, 20 Harley St, London W1M 1AL UK
West. J. Med.
2000
173: 76-78
|
| 27452984 |
Smid A et al.:
PACSIN2 polymorphism is associated with thiopurine-induced hematological toxicity in children with acute lymphoblastic leukaemia undergoing maintenance therapy
Sci Rep
2016
6: 30244
|
| 21807942 |
Hansen CG et al.:
Pacsin 2 is recruited to caveolae and functions in caveolar biogenesis
J. Cell. Sci.
2011
124: 2777-2785
|
| 17030622 |
Bao D et al.:
Cbln1 is essential for interaction-dependent secretion of Cbln3
Mol. Cell. Biol.
2006
26: 9327-9337
|
| 29438981 |
Bernkopf DB et al.:
Pgam5 released from damaged mitochondria induces mitochondrial biogenesis via Wnt signaling
J. Cell Biol.
2018
217: 1383-1394
|
| 20587420 |
Zhou QL et al.:
A novel pleckstrin homology domain-containing protein enhances insulin-stimulated Akt phosphorylation and GLUT4 translocation in adipocytes
J. Biol. Chem.
2010
285
|
| 9218452 |
Collins SP et al.:
Characterization of PKIgamma, a novel isoform of the protein kinase inhibitor of cAMP-dependent protein kinase
J. Biol. Chem.
1997
272
|
| 24910243 |
Sato H et al. et al.:
The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E play distinct roles in obesity
Cell Metab.
2014
20: 119-132
|
| 25139857 |
Choksi SP et al.:
Systematic discovery of novel ciliary genes through functional genomics in the zebrafish
Development
2014
141: 3410-3419
|
| 30881373 |
Mukherjee I et al.:
Identification of Important Effector Proteins in the FOXJ1 Transcriptional Network Associated With Ciliogenesis and Ciliary Function
Front Genet
2019
10: 23
|
| 19931639 |
Bennett NC et al.:
Molecular cell biology of androgen receptor signalling
Int. J. Biochem. Cell Biol.
2010
42: 813-827
|
| 20090367 |
Alam A et al.:
Phenylethanolamine N-methyltransferase gene polymorphisms and adverse outcomes in acute kidney injury
Nephron Clin Pract
2010
114: c253-c259
|
| 24096675 |
Ohmoto M et al.:
Pou2f3/Skn-1a is necessary for the generation or differentiation of solitary chemosensory cells in the anterior nasal cavity
Biosci. Biotechnol. Biochem.
2013
77: 2154-2156
|
| 14612417 |
Hsu LC et al.:
The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription
Mol. Cell. Biol.
2003
23: 8773-8785
|
| 12761501 |
Matsuda A et al.:
Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways
Oncogene
2003
22: 3307-3318
|
| 10406798 |
Conchon S et al.:
Got1p and Sft2p: membrane proteins involved in traffic to the Golgi complex
EMBO J.
1999
18: 3934-3946
|
| 19561403 |
Jung H et al.:
Negative feedback regulation of Wnt signaling by Gbetagamma-mediated reduction of Dishevelled
Exp. Mol. Med.
2009
41: 695-706
|
| 29290589 |
Smith MD et al.:
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis
Dev. Cell
2018
44: 217-232.e11
|
| 17000758 |
Kostenko EV et al.:
Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs
Mol. Cell. Biol.
2006
26: 8964-8975
|
| 7525296 |
Chan AS et al.:
Tyrosine kinase activity associated with the CD7 antigen: correlation with regulation of T cell integrin function
Eur. J. Immunol.
1994
24: 2602-2608
|
| 8601400 |
Okuda A et al.:
An amino acid change in novel protein D123 is responsible for temperature-sensitive G1-phase arrest in a mutant of rat fibroblast line 3Y1
Exp. Cell Res.
1996
223: 242-249
|
| 20074037 |
Manchado E et al.:
The anaphase-promoting complex/cyclosome (APC/C): cell-cycle-dependent and -independent functions
Biochem. Soc. Trans.
2010
38: 65-71
|
| 25723520 |
Masuda K et al.:
LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C
PLoS ONE
2015
10
|
| 22890115 |
Nubling G et al.:
Limited cleavage of tau with matrix-metalloproteinase MMP-9, but not MMP-3, enhances tau oligomer formation
Exp. Neurol.
2012
237: 470-476
|
| 23892277 |
Ivanova MM et al.:
Estradiol and tamoxifen regulate NRF-1 and mitochondrial function in mouse mammary gland and uterus
J. Mol. Endocrinol.
2013
51: 233-246
|
| 19556239 |
Zhang W et al.:
PR55 alpha, a regulatory subunit of PP2A, specifically regulates PP2A-mediated beta-catenin dephosphorylation
J. Biol. Chem.
2009
284
|
| 27521566 |
Hyodo T et al.:
A regulatory subunit of protein phosphatase 2A, PPP2R5E, regulates the abundance of microtubule crosslinking factor 1
FEBS J.
2016
283: 3662-3671
|
| 25972378 |
Loveday C et al. et al.:
Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth
Hum. Mol. Genet.
2015
24: 4775-4779
|
| 19609721 |
Zhang Q et al.:
Polymorphisms in the promoter region of bovine PRKAB1 gene
Mol. Biol. Rep.
2010
37: 435-440
|
| 31581839 |
Shamshoum H et al.:
AMPK beta1 activation suppresses antipsychotic-induced hyperglycemia in mice
FASEB J.
2019
33
|
| 30886105 |
Feng J et al.:
PTEN arginine methylation by PRMT6 suppresses PI3K-AKT signaling and modulates pre-mRNA splicing
Proc. Natl. Acad. Sci. U.S.A.
2019
116: 6868-6877
|
| 30559147 |
Hua X et al.:
Identification of candidate biomarkers associated with apoptosis in melanosis coli: GNG5, LPAR3, MAPK8, and PSMC6
|
| 30615487 |
Cohen-Sharir Y et al.:
Protein tyrosine phosphatase alpha inhibits hypothalamic leptin receptor signaling and regulates body weight in vivo
FASEB J.
2019
33: 5101-5111
|
| 9705027 |
Perez JX et al.:
Effect of starvation on gene expression of regulatory enzymes of glycolysis/gluconeogenesis in genetically obese (fa/fa) Zucker rats
Int. J. Obes. Relat. Metab. Disord.
1998
22: 667-672
|
| 26067360 |
Hansen JS et al. et al.:
Type 2 diabetes alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and recovery
Diabetologia
2015
58: 1845-1854
|
| 3348809 |
Hiraga K et al.:
Cloning of cDNA encoding human H-protein, a constituent of the glycine cleavage system
Biochem. Biophys. Res. Commun.
1988
151: 758-762
|
| 16614080 |
Meton I et al.:
Sterol regulatory element binding protein-1a transactivates 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene promoter
Endocrinology
2006
147: 3446-3456
|
| 14623077 |
Minchenko O et al.:
Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene family (PFKFB-1-4) expression in vivo
FEBS Lett.
2003
554: 264-270
|
| 25662186 |
Muller YL et al. et al.:
A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians
Hum. Mol. Genet.
2015
24: 2985-2996
|
| 17263664 |
Neupert W et al.:
Translocation of proteins into mitochondria
Annu. Rev. Biochem.
2007
76: 723-749
|
| 30964749 |
Barcena de Arellano ML et al.:
Sex differences in the aging human heart: decreased sirtuins, pro-inflammatory shift and reduced anti-oxidative defense
Aging (Albany NY)
2019
11: 1918-1933
|
| 16014032 |
Nagai K et al. et al.:
Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy
Kidney Int.
2005
68: 552-561
|
| 18292389 |
Cavet ME et al.:
Gas6-axl receptor signaling is regulated by glucose in vascular smooth muscle cells
Arterioscler. Thromb. Vasc. Biol.
2008
28: 886-891
|
| 19657094 |
Scutera S et al.:
Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway
J. Immunol.
2009
183: 3004-3013
|
| 19914232 |
Alexander MS et al.:
Foxj3 transcriptionally activates Mef2c and regulates adult skeletal muscle fiber type identity
Dev. Biol.
2010
337: 396-404
|
| 25272951 |
Malfatti E et al. et al.:
A new muscle glycogen storage disease associated with glycogenin-1 deficiency
Ann. Neurol.
2014
76: 891-898
|
| 23781148 |
Liu Q et al.:
Overexpression of DOC-1R inhibits cell cycle G1/S transition by repressing CDK2 expression and activation
Int. J. Biol. Sci.
2013
9: 541-549
|
| 20975297 |
Marrades MP et al.:
A dysregulation in CES1, APOE and other lipid metabolism-related genes is associated to cardiovascular risk factors linked to obesity
Obes Facts
2010
3: 312-318
|
| 18485328 |
Zhu HJ et al.:
Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis
Am. J. Hum. Genet.
2008
82: 1241-1248
|
| 32785227 |
Oura S et al.:
Cfap97d1 is important for flagellar axoneme maintenance and male mouse fertility
PLoS Genet.
2020
16
|
| 10781601 |
Hiraoka N et al.:
Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family
J. Biol. Chem.
2000
275
|
| 26908066 |
Schulster M et al.:
The role of estradiol in male reproductive function
Asian J. Androl.
2016
18: 435-440
|
| 17892469 |
Fabian CJ et al.:
The what, why and how of aromatase inhibitors: hormonal agents for treatment and prevention of breast cancer
Int. J. Clin. Pract.
2007
61: 2051-2063
|
| 19605792 |
Yilmaz MB et al.:
Aromatase promoter I.f is regulated by estrogen receptor alpha (ESR1) in mouse hypothalamic neuronal cell lines
Biol. Reprod.
2009
81: 956-965
|
| 21628418 |
Yilmaz MB et al.:
Aromatase promoter I.f is regulated by progesterone receptor in mouse hypothalamic neuronal cell lines
J. Mol. Endocrinol.
2011
47: 69-80
|
| 31661060 |
author information missing
Bartter syndrome type III with only a synonymous mutation of the CLCNKB gene
Clin. Nephrol.
2019
92: 325-328
|
| 16487665 |
Thilers PP et al.:
The association between endogenous free testosterone and cognitive performance: a population-based study in 35 to 90 year-old men and women
Psychoneuroendocrinology
2006
31: 565-576
|
| 26327881 |
Jakiel G et al.:
Andropause - state of the art 2015 and review of selected aspects
Prz Menopauzalny
2015
14: 1-6
|
| 28655716 |
Ohlsson C et al. et al.:
Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male mice
Am. J. Physiol. Endocrinol. Metab.
2017
313: E450-E462
|
| 20515451 |
Hu J et al.:
Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones
Nutr Metab (Lond)
2010
7: 47
|
| 32561905 |
Park S et al. et al.:
CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity
Biol. Reprod.
2020
103: 195-204
|
| 24885863 |
Goumidi L et al.:
Effects of established BMI-associated loci on obesity-related traits in a French representative population sample
BMC Genet.
2014
15: 62
|
| 22653977 |
Dao KH et al.:
FANCL ubiquitinates beta-catenin and enhances its nuclear function
Blood
2012
120: 323-334
|
| 30804394 |
Georges A et al.:
USP7 Regulates Cytokinesis through FBXO38 and KIF20B
Sci Rep
2019
9: 2724
|
| 26239165 |
Wu Q et al.:
Gremlin 2 inhibits adipocyte differentiation through activation of Wnt/beta-catenin signaling
Mol Med Rep
2015
12: 5891-5896
|
| 21651516 |
Almaghlouth IA et al.:
5-Oxoprolinase deficiency: report of the first human OPLAH mutation
Clin. Genet.
2012
82: 193-196
|
| 29632241 |
Kraus K et al.:
A fragment of adhesion molecule L1 is imported into mitochondria, and regulates mitochondrial metabolism and trafficking
|
| 29127326 |
Lutz D et al.:
Proteolytic cleavage of transmembrane cell adhesion molecule L1 by extracellular matrix molecule Reelin is important for mouse brain development
Sci Rep
2017
7: 15268
|
| 16199880 |
Maretzky T et al.:
L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth
Mol. Cell. Biol.
2005
25: 9040-9053
|
| 25912136 |
Higashi S et al. et al.:
p13 overexpression in pancreatic beta-cells ameliorates type 2 diabetes in high-fat-fed mice
Biochem. Biophys. Res. Commun.
2015
461: 612-617
|
| 28001042 |
Cai K et al.:
Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron-Sulfur Cluster Biosynthesis
Biochemistry
2017
56: 487-499
|
| 21636783 |
Strushkevich N et al.:
Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system
Proc. Natl. Acad. Sci. U.S.A.
2011
108
|
| 10491328 |
Lee JK et al.:
Cloning and characterization of a mammalian N-acetylglucosamine-6-sulfotransferase that is highly restricted to intestinal tissue
Biochem. Biophys. Res. Commun.
1999
263: 543-549
|
| 12218059 |
Akama TO et al.:
Enzymatic synthesis in vitro of the disulfated disaccharide unit of corneal keratan sulfate
J. Biol. Chem.
2002
277
|
| 29743260 |
Zheng B et al.:
Cellular nucleic acid-binding protein is vital to testis development and spermatogenesis in mice
Reproduction
2018
156: 59-69
|
| 17143291 |
Niehrs C et al.:
Function and biological roles of the Dickkopf family of Wnt modulators
Oncogene
2006
25: 7469-7481
|
| 25361606 |
Genereux JC et al.:
Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis
EMBO J.
2015
34: 4-19
|
| 15203207 |
Shiokawa D et al.:
Characterization of the human DNAS1L2 gene and the molecular mechanism for its transcriptional activation induced by inflammatory cytokines
Genomics
2004
84: 95-105
|
| 29618518 |
Zhao Y et al.:
C-terminal domain small phosphatase-like 2 promotes epithelial-to-mesenchymal transition via Snail dephosphorylation and stabilization
|
| 28851713 |
Cao J et al.:
SCP4 Promotes Gluconeogenesis Through FoxO1/3a Dephosphorylation
Diabetes
2018
67: 46-57
|
| 7559396 |
Srivastava M et al.:
Genomic structure and expression of the human gene encoding cytochrome b561, an integral protein of the chromaffin granule membrane
J Biol Chem
1995
270
|
| 25835049 |
Lane DJ et al.:
Duodenal cytochrome b (DCYTB) in iron metabolism: an update on function and regulation
Nutrients
2015
7: 2274-2296
|
| 16618118 |
Yin H et al.:
Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1
Biochemistry
2006
45: 5297-5308
|
| 31377845 |
Martinez-Arribas B et al.:
DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools
Cell Mol Life Sci
2020
77: 1645-1660
|
| 31173446 |
Friese A et al.:
Chemical Genetics Reveals a Role of dCTP Pyrophosphatase 1 in Wnt Signaling
Angew Chem Int Ed Engl
2019
58
|
| 16449189 |
Oda Y et al.:
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation
J Cell Biol
2006
172: 383-393
|
| 29083321 |
Tang X et al. et al.:
EMC3 coordinates surfactant protein and lipid homeostasis required for respiration
J Clin Invest
2017
127: 4314-4325
|
| 19041763 |
Kumar KG et al. et al.:
Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism
Cell Metab
2008
8: 468-481
|
| 27446928 |
Shahjouei S et al.:
Potential Roles of Adropin in Central Nervous System: Review of Current Literature
Front Mol Biosci
2016
3: 25
|
| 24508277 |
Ruiz JC et al.:
F-box and leucine-rich repeat protein 5 (FBXL5): sensing intracellular iron and oxygen
J Inorg Biochem
2014
133: 73-77
|
| 32828318 |
Chen W et al.:
SCF-FBXO24 regulates cell proliferation by mediating ubiquitination and degradation of PRMT6
Biochem Biophys Res Commun
2020
530: 75-81
|
| 30188634 |
author information missing
EEA1 CARRYING VESICLES ARE NOT AUTOPHAGOSOMES IN SERUM-DEPRIVED HeLa CELLS
Tsitologiia
2016
58: 370-377
|
| 29301063 |
Watanabe Y et al.:
Aberrant Epigenetic Gene Regulation in GABAergic Interneuron Subpopulations in the Hippocampal Dentate Gyrus of Mouse Offspring Following Developmental Exposure to Hexachlorophene
Toxicol Sci
2018
163: 13-25
|
| 28579962 |
Clark A et al.:
The Crosstalk between the Gut Microbiota and Mitochondria during Exercise
Front Physiol
2017
8: 319
|
| 2000398 |
Olson JA Jr et al.:
Angiotensin II induces secretion of plasminogen activator inhibitor 1 and a tissue metalloprotease inhibitor-related protein from rat brain astrocytes
Proc Natl Acad Sci U S A
1991
88: 1928-1932
|
| 15958296 |
Wang LJ et al.:
[Angiotensin-(1-7) modulates fibrinolytic imbalance induced by oxidized low-density lipoprotein in cultured human umbilical vein endothelial cells]
Di Yi Jun Yi Da Xue Xue Bao
2005
25: 633-637
|
| 25705216 |
Euro L et al. et al.:
Structural modeling of tissue-specific mitochondrial alanyl-tRNA synthetase (AARS2) defects predicts differential effects on aminoacylation
Front Genet
2015
6: 21
|
| 16908670 |
Jehle AW et al. et al.:
ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages
J Cell Biol
2006
174: 547-556
|
| 7470350 |
author information missing
The glucose-fatty acid-ketone body cycle. Role of ketone bodies as respiratory substrates and metabolic signals
Br J Anaesth
1981
53: 131-136
|
| 32842402 |
Tian XX et al.:
[Effects of early supplement of exogenous L-carnitine on renal function in severely scalded rats]
Zhonghua Shao Shang Za Zhi
2020
36: 553-559
|
| 25776077 |
Koulis C et al.:
AT2R agonist, compound 21, is reno-protective against type 1 diabetic nephropathy
Hypertension
2015
65: 1073-1081
|
| 24326387 |
Chen CT et al.:
Inhibiting mitochondrial beta-oxidation selectively reduces levels of nonenzymatic oxidative polyunsaturated fatty acid metabolites in the brain
J Cereb Blood Flow Metab
2014
34: 376-379
|
| 28755194 |
author information missing
Nitisinone }, from book { title { name LiverTox: Clinical and Research Information on Drug-Induced Liver Injury }, authors { names ml { } }, imp { date std { year 2012 }, language eng, pubstatus ppublish, history { { pubstatus pubmed, date std { year 2019, month 10, day 24, hour 6, minute 1 } }, { pubstatus medline, date std { year 2019, month 10, day 24, hour 6, minute 1 } }, { pubstatus other, date std { year 2019, month 10, day 24, hour 6, minute 1 } } } } }, ids { pubmed 31643958 } }, abstract Nitisinone is an inhibitor of the tyrosine catabolism that is used to treat hereditary tyrosinemia, type 1, in which accumulation of intermediates of tyrosine metabolism causes severe and progressive hepatic and renal injury. Nitisinone has been associated with mild, transient serum aminotransferase elevations, but has not been linked to instances of clinically apparent acute liver injury or jaundice
|
| 26610751 |
Montesinos Mdel M et al.:
Nitric oxide-repressed Forkhead factor FoxE1 expression is involved in the inhibition of TSH-induced thyroid peroxidase levels
Mol Cell Endocrinol
2016
420: 105-115
|
| 27658324 |
Skalska J et al.:
Oxidative stress in rat brain but not in liver following oral administration of a low dose of nanoparticulate silver
Food Chem Toxicol
2016
97: 307-315
|
| 3202963 |
Popovic T et al.:
A new purification procedure of human kidney cathepsin H, its properties and kinetic data
Biol Chem Hoppe Seyler
1988
369: Suppl 175-183
|
| 12065237 |
Ramsden JD et al.:
Thyroid follicular cells secrete plasminogen activators and can form angiostatin from plasminogen
J Endocrinol
2002
173: 475-481
|
| 28103777 |
Zbigniew S et al.:
Role of Iodine in Metabolism
Recent Pat Endocr Metab Immune Drug Discov
2017
10: 123-126
|
| 21453200 |
Galino J et al. et al.:
Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy
Antioxid Redox Signal
2011
15: 2095-2107
|
| 32161193 |
Morigi M et al.:
C3a receptor blockade protects podocytes from injury in diabetic nephropathy
|
| 24448649 |
Martina JA et al.:
The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris
Sci Signal
2014
7: ra9
|
| 23596049 |
Hoffmeister A et al. et al.:
Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression
Obesity (Silver Spring)
2013
21: E626-E633
|
| 14927637 |
author information missing
Specificity of amino acid acylases
J Biol Chem
1952
194: 455-470
|
| 17723438 |
Gerlo E et al.:
Gas chromatographic-mass spectrometric analysis of N-acetylated amino acids: the first case of aminoacylase I deficiency
Anal Chim Acta
2006
571: 191-199
|
| 18362890 |
author information missing
article information missing
|
| 20083229 |
Amara S et al.:
Lipolysis of natural long chain and synthetic medium chain galactolipids by pancreatic lipase-related protein 2
Biochim Biophys Acta
2010
1801: 508-516
|
| 27684187 |
Rosenbluh J et al. et al.:
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in beta-Catenin-Active Cancers
Cell Syst
2016
3: 302-316.e4
|
| 22306379 |
Praekelt U et al. et al.:
New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2
Eur J Cell Biol
2012
91: 180-191
|
| 11294894 |
Bono P et al.:
Layilin, a novel integral membrane protein, is a hyaluronan receptor
Mol Biol Cell
2001
12: 891-900
|
| 31221957 |
Yeo EJ et al.:
Hypoxia and aging
Exp Mol Med
2019
51: 1-15
|
| 12774311 |
Gu F et al.:
Testosterone up-regulates aquaporin-4 expression in cultured astrocytes
J Neurosci Res
2003
72: 709-715
|
| 18778410 |
Chen L et al.:
Reduction of mitochondrial H2O2 by overexpressing peroxiredoxin 3 improves glucose tolerance in mice
Aging Cell
2008
7: 866-878
|
| 25462069 |
Cunniff B et al.:
Peroxiredoxin 3 levels regulate a mitochondrial redox setpoint in malignant mesothelioma cells
Redox Biol
2014
3: 79-87
|
| 24564666 |
Hejzlarova K et al.:
Nuclear genetic defects of mitochondrial ATP synthase
Physiol Res
2014
63: S57-S71
|
| 32368089 |
Guo F et al.:
Tumor Necrosis Factor Alpha-Induced Proteins in Malignant Tumors: Progress and Prospects
Onco Targets Ther
2020
13: 3303-3318
|
| 9651365 |
Huang B et al.:
Isoenzymes of pyruvate dehydrogenase phosphatase. DNA-derived amino acid sequences, expression, and regulation
J Biol Chem
1998
273
|
| 7324866 |
author information missing
Cerebral blood flow and metabolic rate of oxygen, glucose, lactate, pyruvate, ketone bodies and amino acids
Acta Neurol Scand
1981
63: 337-350
|
| 17433303 |
Kikuchi R et al. et al.:
Mechanism of vitamin D3-induced transcription of phospholipase D1 in HaCat human keratinocytes
FEBS Lett
2007
581: 1800-1804
|
| 20466847 |
Leng S et al.:
Glycogen synthase kinase 3 beta mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1
J Endocrinol
2010
206: 171-181
|
| 21738790 |
Wu D et al.:
Overexpression of SIRT1 in mouse forebrain impairs lipid/glucose metabolism and motor function
PLoS One
2011
6
|
| 19451232 |
Lee MN et al.:
Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb
Mol Cell Biol
2009
29: 3991-4001
|
| 16923831 |
Wang J et al.:
Restricted epithelial proliferation by lacritin via PKCalpha-dependent NFAT and mTOR pathways
J Cell Biol
2006
174: 689-700
|
| 14653992 |
Fang Y et al.:
PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1
Curr Biol
2003
13: 2037-2044
|
| 16249387 |
Ahn E et al.:
LIME acts as a transmembrane adapter mediating BCR-dependent B-cell activation
Blood
2006
107: 1521-1527
|
| 26269414 |
Fekrmandi F et al.:
The hormone-bound vitamin D receptor enhances the FBW7-dependent turnover of NF-kappaB subunits
Sci Rep
2015
5: 13002
|
| 20231899 |
Kim JH et al.:
Phospholipase D1 mediates AMP-activated protein kinase signaling for glucose uptake
PLoS One
2010
5: e9600
|
| 20427710 |
Winter JN et al.:
Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway
Am J Physiol Cell Physiol
2010
299: C335-C344
|
| 19382910 |
Obradovic D et al.:
Vitamin D3 signalling in the brain enhances the function of phosphoprotein enriched in astrocytes--15 kD (PEA-15)
J Cell Mol Med
2009
13: 3315-3328
|
| 11702783 |
Formstecher E et al.:
PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase
Dev Cell
2001
1: 239-250
|
| 24657708 |
Greig FH et al.:
Phosphoprotein enriched in astrocytes (PEA)-15: a potential therapeutic target in multiple disease states
Pharmacol Ther
2014
143: 265-274
|
| 11733517 |
Stegh AH et al.:
Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein
J Biol Chem
2002
277: 4351-4360
|
| 10662719 |
Zhou YP et al. et al.:
Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion
Am J Physiol Endocrinol Metab
2000
278: E340-E351
|
| 23253615 |
Heslegrave AJ et al.:
Novel insights into fatty acid oxidation, amino acid metabolism, and insulin secretion from studying patients with loss of function mutations in 3-hydroxyacyl-CoA dehydrogenase
J Clin Endocrinol Metab
2013
98: 496-501
|
| 21677994 |
Zhang H et al.:
Complement component C4A and apolipoprotein A-I in plasmas as biomarkers of the severe, early-onset preeclampsia
Mol Biosyst
2011
7: 2470-2479
|
| 14592415 |
Ikeda Y et al.:
Posttranscriptional regulation of human ABCA7 and its function for the apoA-I-dependent lipid release
Biochem Biophys Res Commun
2003
311: 313-318
|
| 21567405 |
Kim N et al. et al.:
Human nuclear clusterin mediates apoptosis by interacting with Bcl-XL through C-terminal coiled coil domain
J Cell Physiol
2012
227: 1157-1167
|
| 15314688 |
Lantz KA et al.:
Foxa2 regulates multiple pathways of insulin secretion
J Clin Invest
2004
114: 512-520
|
| 14676218 |
Johansson C et al.:
Human mitochondrial glutaredoxin reduces S-glutathionylated proteins with high affinity accepting electrons from either glutathione or thioredoxin reductase
J Biol Chem
2004
279: 7537-7543
|
| 20194533 |
Lee AC et al.:
Up-regulation of human CYP2J2 in HepG2 cells by butylated hydroxyanisole is mediated by c-Jun and Nrf2
Mol Pharmacol
2010
77: 987-994
|
| 7836456 |
Dirkx R Jr et al.:
Targeting of the 67-kDa isoform of glutamic acid decarboxylase to intracellular organelles is mediated by its interaction with the NH2-terminal region of the 65-kDa isoform of glutamic acid decarboxylase
J Biol Chem
1995
270: 2241-2246
|
| 15546613 |
Hayakawa J et al.:
Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress
Mol Cell
2004
16: 521-535
|
| 8608946 |
Ohno M et al.:
A human RNA helicase-like protein, HRH1, facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome
Genes Dev
1996
10: 997-1007
|
| 22863883 |
Kristensen AR et al.:
A high-throughput approach for measuring temporal changes in the interactome
Nat Methods
2012
9: 907-909
|
| 10217402 |
Zhang H et al.:
Novel BNIP1 variants and their interaction with BCL2 family members
FEBS Lett
1999
448: 23-27
|
| 22020994 |
Ryu SW et al.:
Endoplasmic reticulum-specific BH3-only protein BNIP1 induces mitochondrial fragmentation in a Bcl-2- and Drp1-dependent manner
J Cell Physiol
2012
227: 3027-3035
|
| 33434211 |
Vangrieken P et al.:
Hypoxia-induced mitochondrial abnormalities in cells of the placenta
PLoS One
2021
16
|
| 11449084 |
Deguchi K et al.:
Postmenopausal changes in production of type 1 and type 2 cytokines and the effects of hormone replacement therapy
Menopause
2001
8: 266-273
|
| 12477727 |
Smith IF et al.:
Hypoxic remodeling of Ca2+ stores in type I cortical astrocytes
J Biol Chem
2003
278: 4875-4881
|
| 16276418 |
Ward ME et al.:
Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant
J Clin Invest
2005
115: 3128-3139
|
| 16212810 |
Bergers G et al.:
The role of pericytes in blood-vessel formation and maintenance
Neuro Oncol
2005
7: 452-464
|
| 28973891 |
Wang H et al.:
Complement-activation fragment C4a mediates effector functions by binding as untethered agonist to protease-activated receptors 1 and 4
Proc Natl Acad Sci U S A
2017
114
|
| 15755733 |
Lee CC et al.:
Insulin stimulates postsynaptic density-95 protein translation via the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway
J Biol Chem
2005
280
|
| 22588366 |
Sahin E et al.:
Axis of ageing: telomeres, p53 and mitochondria
Nat Rev Mol Cell Biol
2012
13: 397-404
|
| 28298427 |
Sokolina K et al. et al.:
Systematic protein-protein interaction mapping for clinically relevant human GPCRs
Mol Syst Biol
2017
13: 918
|
| 15643130 |
Imanishi T et al.:
Angiotensin II accelerates endothelial progenitor cell senescence through induction of oxidative stress
J Hypertens
2005
23: 97-104
|
| 29351466 |
Ait-Aissa K et al.:
Telomerase reverse transcriptase protects against angiotensin II-induced microvascular endothelial dysfunction
Am J Physiol Heart Circ Physiol
2018
314
|
| 20876939 |
Kuhlow D et al.:
Telomerase deficiency impairs glucose metabolism and insulin secretion
Aging (Albany NY)
2010
2: 650-658
|
| 9748214 |
Liu M et al.:
A human RNA polymerase II transcription termination factor is a SWI2/SNF2 family member
J Biol Chem
1998
273
|
| 11062248 |
Sturany S et al.:
Molecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase D family of serine threonine kinases
J Biol Chem
2001
276: 3310-3318
|
| 30759120 |
Zhang M et al. et al.:
SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress
PLoS One
2019
14
|
| 31702900 |
Luo M et al.:
Deletion of the Mitochondrial Protein VWA8 Induces Oxidative Stress and an HNF4alpha Compensatory Response in Hepatocytes
Biochemistry
2019
58: 4983-4996
|
| 26972000 |
Rodriguez J et al.:
Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways
Cell Rep
2016
14: 2745-2760
|
| 20186120 |
Richter R et al.:
A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome
EMBO J
2010
29: 1116-1125
|
| 33092611 |
Pavlu-Pereira H et al. et al.:
Pyruvate dehydrogenase complex deficiency: updating the clinical, metabolic and mutational landscapes in a cohort of Portuguese patients
Orphanet J Rare Dis
2020
15: 298
|
| 15850985 |
Snyder JR et al.:
Dissection of melanogenesis with small molecules identifies prohibitin as a regulator
Chem Biol
2005
12: 477-484
|
| 15705887 |
Ma DW et al. et al.:
Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis
Cancer Res
2005
65: 887-897
|
| 21752681 |
Dill P et al.:
Pyridoxal phosphate-responsive seizures in a patient with cerebral folate deficiency (CFD) and congenital deafness with labyrinthine aplasia, microtia and microdontia (LAMM)
Mol Genet Metab
2011
104: 362-368
|
| 10843999 |
Luong A et al.:
Molecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteins
J Biol Chem
2000
275
|
| 21598311 |
Moffett JR et al.:
Extensive aspartoacylase expression in the rat central nervous system
Glia
2011
59: 1414-1434
|
| 30375385 |
Huang N et al.:
M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole
Nat Commun
2018
9: 4511
|
| 22637578 |
Sardar HS et al.:
Microtubule capture by mitotic kinesin centromere protein E (CENP-E)
J Biol Chem
2012
287
|
| 23891108 |
Shrestha RL et al.:
Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK
Curr Biol
2013
23: 1514-1526
|
| 12361599 |
Putkey FR et al.:
Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E
Dev Cell
2002
3: 351-365
|
| 12147251 |
Wang T et al.:
Both tissue inhibitors of metalloproteinases-1 (TIMP-1) and TIMP-2 activate Ras but through different pathways
Biochem Biophys Res Commun
2002
296: 201-205
|
| 18721821 |
Seo DW et al.:
TIMP-2 disrupts FGF-2-induced downstream signaling pathways
Microvasc Res
2008
76: 145-151
|
| 26331622 |
Valacca C et al.:
TIMP-2 Interaction with MT1-MMP Activates the AKT Pathway and Protects Tumor Cells from Apoptosis
PLoS One
2015
10
|
| 22327515 |
Wang C et al. et al.:
Mutations in SLC20A2 link familial idiopathic basal ganglia calcification with phosphate homeostasis
Nat Genet
2012
44: 254-256
|
| 26891959 |
Wang W et al.:
Alu RNA accumulation in hyperglycemia augments oxidative stress and impairs eNOS and SOD2 expression in endothelial cells
Mol Cell Endocrinol
2016
426: 91-100
|
| 30944090 |
Milano CR et al.:
Mutation of the ATPase Domain of MutS Homolog-5 (MSH5) Reveals a Requirement for a Functional MutSgamma Complex for All Crossovers in Mammalian Meiosis
G3 (Bethesda)
3 (B
9: 1839-1850
|
| 22917773 |
Bannwarth S et al. et al.:
The human MSH5 (MutSHomolog 5) protein localizes to mitochondria and protects the mitochondrial genome from oxidative damage
Mitochondrion
2012
12: 654-665
|
| 25658088 |
Wen JL et al.:
UBE3C promotes growth and metastasis of renal cell carcinoma via activating Wnt/beta-catenin pathway
PLoS One
2015
10
|
| 16954335 |
Rodriguez-Cuenca S et al.:
Expression of mitochondrial biogenesis-signaling factors in brown adipocytes is influenced specifically by 17beta-estradiol, testosterone, and progesterone
Am J Physiol Endocrinol Metab
2007
292: E340-E346
|
| 14760703 |
Navarro-Lerida I et al.:
Proteomic identification of brain proteins that interact with dynein light chain LC8
Proteomics
2004
4: 339-346
|
| 29768513 |
Zhang D et al.:
Increased mitochondrial fission is critical for hypoxia-induced pancreatic beta cell death
PLoS One
2018
13
|
| 23834359 |
Brentnall M et al.:
Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis
BMC Cell Biol
2013
14: 32
|
| 9922454 |
Slee EA et al.:
Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
J Cell Biol
1999
144: 281-292
|
| 33257366 |
Joseph VM et al.:
Sequential spontaneous compartment syndrome in multiple limbs in a young adult with GYG1 gene mutation
|
| 32905144 |
Nicolau S et al.:
GYG1: A distal myopathy with polyglucosan bodies
JIMD Rep
2020
55: 88-90
|
| 1459471 |
Oka Y et al.:
Expression of glucose transporter isoforms with aging
Gerontology
1992
38: Suppl 1 3-9
|
| 16862226 |
Moeller LC et al.:
Thyroid hormone mediated changes in gene expression can be initiated by cytosolic action of the thyroid hormone receptor beta through the phosphatidylinositol 3-kinase pathway
Nucl Recept Signal
2006
4: e020
|
| 19876643 |
Perez de Heredia F et al.:
Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes
Pflugers Arch
2010
459: 509-518
|
| 24619881 |
Sakagami H et al.:
Loss of HIF-1alpha impairs GLUT4 translocation and glucose uptake by the skeletal muscle cells
Am J Physiol Endocrinol Metab
2014
306
|
| 11292650 |
Cheng CM et al.:
Estrogen augments glucose transporter and IGF1 expression in primate cerebral cortex
FASEB J
2001
15: 907-915
|
| 28508346 |
Antinozzi C et al.:
Testosterone insulin-like effects: an in vitro study on the short-term metabolic effects of testosterone in human skeletal muscle cells
J Endocrinol Invest
2017
40: 1133-1143
|
| 27765882 |
Mishra JS et al.:
Testosterone downregulates angiotensin II type-2 receptor via androgen receptor-mediated ERK1/2 MAP kinase pathway in rat aorta
|
| 18568013 |
Knott AB et al.:
Mitochondrial fragmentation in neurodegeneration
Nat Rev Neurosci
2008
9: 505-518
|
| 12861026 |
Yoon Y et al.:
The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1
Mol Cell Biol
2003
23: 5409-5420
|
| 3067252 |
Sherwin BB et al.:
Estrogen and/or androgen replacement therapy and cognitive functioning in surgically menopausal women
Psychoneuroendocrinology
1988
13: 345-357
|
| 11686488 |
Hamlin GP et al.:
Increased expression of neuronal glucose transporter 3 but not glial glucose transporter 1 following severe diffuse traumatic brain injury in rats
J Neurotrauma
2001
18: 1011-1018
|
| 21468560 |
Feng X et al.:
Change of telomere length in angiotensin II-induced human glomerular mesangial cell senescence and the protective role of losartan
Mol Med Rep
2011
4: 255-260
|
| 24970747 |
Shaheen F et al.:
Extra-nuclear telomerase reverse transcriptase (TERT) regulates glucose transport in skeletal muscle cells
Biochim Biophys Acta
2014
1842: 1762-1769
|
| 16785237 |
Li H et al.:
Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene
J Biol Chem
2006
281
|
| 16374430 |
Huang Y et al.:
Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
Kidney Int
2006
69: 105-113
|
| 30309204 |
author information missing
article information missing
|
| 31527264 |
author information missing
article information missing
|
| 26831301 |
author information missing
article information missing
|
| 26608077 |
author information missing
article information missing
|
| 25535282 |
author information missing
article information missing
|
| 31316342 |
author information missing
article information missing
|
| 12969152 |
author information missing
article information missing
|
| 23455425 |
author information missing
article information missing
|
| 15924567 |
author information missing
article information missing
|
| 23018488 |
author information missing
article information missing
|
| 15196915 |
author information missing
article information missing
|
| 7531712 |
author information missing
article information missing
|
| 7692021 |
author information missing
article information missing
|
| 10825452 |
author information missing
article information missing
|
| 15553237 |
author information missing
article information missing
|
| 27488221 |
author information missing
article information missing
|
| 9426230 |
author information missing
article information missing
|
| 21981923 |
author information missing
article information missing
|
| 23232451 |
author information missing
article information missing
|
| 22683290 |
author information missing
article information missing
|
| 30400066 |
author information missing
article information missing
|
| 15956714 |
author information missing
article information missing
|
| 12923195 |
author information missing
article information missing
|
| 32074073 |
author information missing
article information missing
|
| 33125709 |
author information missing
article information missing
|
| 34986332 |
author information missing
article information missing
|
| 20053669 |
author information missing
article information missing
|
| 17510655 |
author information missing
article information missing
|
| 15644312 |
author information missing
article information missing
|
| 25781180 |
author information missing
article information missing
|
| 17624330 |
author information missing
article information missing
|
| 26004228 |
author information missing
article information missing
|
| 32105825 |
author information missing
article information missing
|
| 19182799 |
author information missing
article information missing
|
| 16185709 |
author information missing
article information missing
|
| 23186364 |
author information missing
article information missing
|
| 22214851 |
author information missing
article information missing
|
| 33921425 |
author information missing
article information missing
|
| 26387864 |
author information missing
article information missing
|
| 30093355 |
author information missing
article information missing
|
| 24145748 |
author information missing
article information missing
|
| 16227571 |
author information missing
article information missing
|
| 33087848 |
author information missing
article information missing
|
| 23414517 |
author information missing
article information missing
|
| 27329800 |
author information missing
article information missing
|
| 27073999 |
author information missing
article information missing
|
| 16752004 |
author information missing
article information missing
|
| 29301957 |
author information missing
article information missing
|
| 18056631 |
author information missing
article information missing
|
| 29423269 |
author information missing
article information missing
|
| 32843574 |
author information missing
article information missing
|
| 26477565 |
author information missing
article information missing
|
| 23676277 |
author information missing
article information missing
|
| 30598479 |
author information missing
article information missing
|
| 35399520 |
author information missing
article information missing
|
| 15007061 |
author information missing
article information missing
|
| 29094215 |
author information missing
article information missing
|
| 2174075 |
author information missing
article information missing
|
| 2362224 |
author information missing
article information missing
|
| 28759161 |
author information missing
article information missing
|
| 28894120 |
author information missing
article information missing
|
| 29158183 |
author information missing
article information missing
|
| 26110892 |
author information missing
article information missing
|
| 31208147 |
author information missing
article information missing
|
| 12450897 |
author information missing
article information missing
|
| 20448042 |
author information missing
article information missing
|
| 27880078 |
author information missing
article information missing
|
| 18651315 |
author information missing
article information missing
|
| 10767287 |
author information missing
article information missing
|
| 15328363 |
author information missing
article information missing
|
| 8330686 |
author information missing
article information missing
|
| 10562279 |
author information missing
article information missing
|
| 10889202 |
author information missing
article information missing
|
| 3405380 |
author information missing
article information missing
|
| 22443876 |
author information missing
article information missing
|
| 1516599 |
author information missing
article information missing
|
| 11397814 |
author information missing
article information missing
|
| 33505966 |
author information missing
article information missing
|
| 33602293 |
author information missing
article information missing
|
| 31678070 |
author information missing
article information missing
|
| 11751922 |
author information missing
article information missing
|
| 30721374 |
author information missing
article information missing
|
| 36047226 |
author information missing
article information missing
|
| 20610884 |
author information missing
article information missing
|
| 8100221 |
author information missing
article information missing
|
| 20153313 |
author information missing
article information missing
|
| 30126342 |
author information missing
article information missing
|
| 14660679 |
author information missing
article information missing
|
| 18484747 |
author information missing
article information missing
|
| 19782107 |
author information missing
article information missing
|
| 30778852 |
author information missing
article information missing
|
| 32269044 |
author information missing
article information missing
|
| 12650930 |
author information missing
article information missing
|
| 3549723 |
author information missing
article information missing
|
| 37414147 |
author information missing
article information missing
|
| 33244184 |
author information missing
article information missing
|
| 35803572 |
author information missing
article information missing
|
| 10427098 |
Faulkner G et al.:
ZASP: a new Z-band alternatively spliced PDZ-motif protein
J. Cell Biol.
1999
146: 465-475
|
| 11842093 |
Frey N et al.:
Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins
J. Biol. Chem.
2002
277
|
| 9501083 |
Young P et al.:
Molecular structure of the sarcomeric Z-disk: two types of titin interactions lead to an asymmetrical sorting of alpha-actinin
EMBO J.
1998
17: 1614-1624
|
| 23414517 |
Blandin G et al.:
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome
Skelet Muscle
2013
3: 3
|
| 23824909 |
Chen Y et al.:
Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity
Mol. Cell Proteomics
2013
12: 2804-2819
|
| 19293945 |
Bell R et al.:
A human protein interaction network shows conservation of aging processes between human and invertebrate species
PLoS Genet.
2009
5
|
| 14583192 |
Miller MK et al.:
The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules
J. Mol. Biol.
2003
333: 951-964
|
| 9348293 |
Kowalczyk AP et al.:
The amino-terminal domain of desmoplakin binds to plakoglobin and clusters desmosomal cadherin-plakoglobin complexes
J. Cell Biol.
1997
139: 773-784
|
| 9261168 |
Meng JJ et al.:
Two-hybrid analysis reveals fundamental differences in direct interactions between desmoplakin and cell type-specific intermediate filaments
J. Biol. Chem.
1997
272
|
| 9443898 |
Marcozzi C et al.:
Coexpression of both types of desmosomal cadherin and plakoglobin confers strong intercellular adhesion
J. Cell. Sci.
1998
111: 495-509
|
| 21220045 |
Gehmlich K et al.:
A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions
Heart Rhythm
2011
8: 711-718
|
| 17897939 |
Zhang W et al.:
Integrin-linked kinase regulates N-WASp-mediated actin polymerization and tension development in tracheal smooth muscle
J. Biol. Chem.
2007
282
|
| 25037680 |
Biagini E et al.:
Significance of sarcomere gene mutations analysis in the end-stage phase of hypertrophic cardiomyopathy
Am. J. Cardiol.
2014
114: 769-776
|
| 11171996 |
Takada F et al.:
Myozenin: an alpha-actinin- and gamma-filamin-binding protein of skeletal muscle Z lines
Proc. Natl. Acad. Sci. U.S.A.
2001
98: 1595-1600
|
| 22028589 |
Knoll R et al.:
The sarcomeric Z-disc and Z-discopathies
J. Biomed. Biotechnol.
2011
2011
|
| 20801532 |
author information missing
Analysis of the Z-disc genes PDLIM3 and MYPN in patients with hypertrophic cardiomyopathy
Int. J. Cardiol.
2010
145: 601-602
|
| 24625729 |
Linke WA et al.:
Gigantic business: titin properties and function through thick and thin
Circ. Res.
2014
114: 1052-1068
|
| 18521710 |
Reddy KB et al.:
Nuclear localization of Myomesin-1: possible functions
J. Muscle Res. Cell. Motil.
2008
29: 1-8
|
| 24462755 |
Xue K et al.:
Molecular characterization and expression patterns of the actinin-associated LIM protein (ALP) subfamily genes in porcine skeletal muscle
Gene
2014
539: 111-116
|
| 15802564 |
Lange S et al.:
The kinase domain of titin controls muscle gene expression and protein turnover
Science
2005
308: 1599-1603
|
| 25381372 |
Endo T et al.:
Glycobiology of alpha-dystroglycan and muscular dystrophy
|
| 16000376 |
Stone MR et al.:
Specific interaction of the actin-binding domain of dystrophin with intermediate filaments containing keratin 19
Mol. Biol. Cell
2005
16: 4280-4293
|
| 18468620 |
Hirner S et al.:
MuRF1-dependent regulation of systemic carbohydrate metabolism as revealed from transgenic mouse studies
J. Mol. Biol.
2008
379: 666-677
|
| 10672519 |
Miyamoto CA et al.:
The interface between MyBP-C and myosin: site-directed mutagenesis of the CX myosin-binding domain of MyBP-C
J. Muscle Res. Cell. Motil.
1999
20: 703-715
|
| 7588733 |
Obermann WM et al.:
Purification and biochemical characterization of myomesin, a myosin-binding and titin-binding protein, from bovine skeletal muscle
Eur. J. Biochem.
1995
233: 110-115
|
| 11305911 |
Joseph C et al.:
A structural characterization of the interactions between titin Z-repeats and the alpha-actinin C-terminal domain
Biochemistry
2001
40: 4957-4965
|
| 15582318 |
Hayashi T et al.:
Tcap gene mutations in hypertrophic cardiomyopathy and dilated cardiomyopathy
J. Am. Coll. Cardiol.
2004
44: 2192-2201
|
| 19622741 |
Bertz M et al.:
The titin-telethonin complex is a directed, superstable molecular bond in the muscle Z-disk
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 17875930 |
Potthoff MJ et al.:
Regulation of skeletal muscle sarcomere integrity and postnatal muscle function by Mef2c
Mol. Cell. Biol.
2007
27: 8143-8151
|
| 12061776 |
Maeda T et al.:
TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters
Biochem. Biophys. Res. Commun.
2002
294: 791-797
|
| 12861002 |
Karasseva N et al.:
Transcription enhancer factor 1 binds multiple muscle MEF2 and A/T-rich elements during fast-to-slow skeletal muscle fiber type transitions
Mol. Cell. Biol.
2003
23: 5143-5164
|
| 20133654 |
Pernigo S et al.:
Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 2908-2913
|
| 19933576 |
Haque F et al.:
Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes
J. Biol. Chem.
2010
285: 3487-3498
|
| 17962350 |
De Alvaro C et al.:
Nuclear exclusion of forkhead box O and Elk1 and activation of nuclear factor-kappaB are required for C2C12-RasV12C40 myoblast differentiation
Endocrinology
2008
149: 793-801
|
| 20515474 |
Ghahramani Seno MM et al.:
Transcriptomic analysis of dystrophin RNAi knockdown reveals a central role for dystrophin in muscle differentiation and contractile apparatus organization
BMC Genomics
2010
11: 345
|
| 16352659 |
Huang G et al.:
ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice
J. Cell. Sci.
2006
119: 153-161
|
| 12509414 |
Zhang H et al.:
A noncontiguous, intersubunit binding site for calmodulin on the skeletal muscle Ca2+ release channel
J. Biol. Chem.
2003
278: 8348-8355
|
| 11532985 |
Matsuda C et al.:
The sarcolemmal proteins dysferlin and caveolin-3 interact in skeletal muscle
Hum. Mol. Genet.
2001
10: 1761-1766
|
| 9334352 |
Xia H et al.:
Actinin-associated LIM protein: identification of a domain interaction between PDZ and spectrin-like repeat motifs
J. Cell Biol.
1997
139: 507-515
|
| 15062084 |
Au Y et al.:
Solution structure of ZASP PDZ domain; implications for sarcomere ultrastructure and enigma family redundancy
Structure
2004
12: 611-622
|
| 17111365 |
Meissner JD et al.:
Activation of the beta myosin heavy chain promoter by MEF-2D, MyoD, p300, and the calcineurin/NFATc1 pathway
J. Cell. Physiol.
2007
211: 138-148
|
| 6746613 |
author information missing
Interactions among chymotryptic troponin T subfragments, tropomyosin, troponin I and troponin C
J. Biochem.
1984
95: 1417-1421
|
| 24043862 |
Mamidi R et al.:
Divergent effects of alpha- and beta-myosin heavy chain isoforms on the N terminus of rat cardiac troponin T
J. Gen. Physiol.
2013
142: 413-423
|
| 10328815 |
Hance JE et al.:
alpha-actinin-2 is a new component of the dystrophin-glycoprotein complex
Arch. Biochem. Biophys.
1999
365: 216-222
|
| 21536590 |
Seto JT et al.:
Deficiency of alpha-actinin-3 is associated with increased susceptibility to contraction-induced damage and skeletal muscle remodeling
Hum. Mol. Genet.
2011
20: 2914-2927
|
| 19109891 |
Ayalon G et al.:
An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan
Cell
2008
135: 1189-1200
|
| 21186323 |
Ayalon G et al.:
Ankyrin-B interactions with spectrin and dynactin-4 are required for dystrophin-based protection of skeletal muscle from exercise injury
J. Biol. Chem.
2011
286: 7370-7378
|
| 21832073 |
Eom GH et al. et al.:
Histone methyltransferase SETD3 regulates muscle differentiation
J. Biol. Chem.
2011
286
|
| 16858404 |
Mal AK et al.:
Histone methyltransferase Suv39h1 represses MyoD-stimulated myogenic differentiation
EMBO J.
2006
25: 3323-3334
|
| 10607832 |
Davis DB et al.:
Myoferlin, a candidate gene and potential modifier of muscular dystrophy
Hum. Mol. Genet.
2000
9: 217-226
|
| 10606664 |
Kataoka H et al.:
A novel snail-related transcription factor Smuc regulates basic helix-loop-helix transcription factor activities via specific E-box motifs
Nucleic Acids Res.
2000
28: 626-633
|
| 23365102 |
Weterman MA et al. et al.:
Recessive MYL2 mutations cause infantile type I muscle fibre disease and cardiomyopathy
Brain
2013
136: 282-293
|
| 25569348 |
Scaramuzzino C et al. et al.:
Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy
Neuron
2015
85: 88-100
|
| 22428544 |
Wang SC et al.:
CARM1/PRMT4 is necessary for the glycogen gene expression programme in skeletal muscle cells
Biochem. J.
2012
444: 323-331
|
| 31623157 |
Han S et al.:
Myoferlin Regulates Wnt/beta-Catenin Signaling-Mediated Skeletal Muscle Development by Stabilizing Dishevelled-2 Against Autophagy
|
| 24737641 |
Yang LX et al.:
MicroRNA-155 inhibits angiotensin II-induced vascular smooth muscle cell proliferation
J Renin Angiotensin Aldosterone Syst
2014
15: 109-116
|
| 27525440 |
author information missing
article information missing
|
| 20207454 |
author information missing
article information missing
|
| 23991007 |
author information missing
article information missing
|
| 16924593 |
Stump RJ et al.:
Lithium stabilizes the polarized lens epithelial phenotype and inhibits proliferation, migration, and epithelial mesenchymal transition
J. Pathol.
2006
210: 249-257
|
| 23669349 |
Lee J et al.:
Bcl6a function is required during optic cup formation to prevent p53-dependent apoptosis and colobomata
Hum. Mol. Genet.
2013
22: 3568-3582
|
| 10601035 |
Bertuzzi S et al.:
The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain
Genes Dev.
1999
13: 3092-3105
|
| 21767579 |
Overlack N et al.:
Direct interaction of the Usher syndrome 1G protein SANS and myomegalin in the retina
Biochim. Biophys. Acta
2011
1813: 1883-1892
|
| 8394174 |
McLaughlin ME et al.:
Recessive mutations in the gene encoding the beta-subunit of rod phosphodiesterase in patients with retinitis pigmentosa
Nat. Genet.
1993
4: 130-134
|
| 8075643 |
Gal A et al.:
Heterozygous missense mutation in the rod cGMP phosphodiesterase beta-subunit gene in autosomal dominant stationary night blindness
Nat. Genet.
1994
7: 64-68
|
| 29555955 |
Birtel J et al. et al.:
Clinical and genetic characteristics of 251 consecutive patients with macular and cone/cone-rod dystrophy
Sci Rep
2018
8: 4824
|
| 25018096 |
Roosing S et al. et al.:
Disruption of the basal body protein POC1B results in autosomal-recessive cone-rod dystrophy
Am. J. Hum. Genet.
2014
95: 131-142
|
| 26350515 |
Bosch DG et al.:
Novel genetic causes for cerebral visual impairment
Eur. J. Hum. Genet.
2016
24: 660-665
|
| 28813576 |
Persad PJ et al.:
Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1
Invest. Ophthalmol. Vis. Sci.
2017
58: 4027-4038
|
| 19896113 |
Audo I et al. et al.:
TRPM1 is mutated in patients with autosomal-recessive complete congenital stationary night blindness
Am. J. Hum. Genet.
2009
85: 720-729
|
| 25749990 |
Di Gioia SA et al.:
Interactome analysis reveals that FAM161A, deficient in recessive retinitis pigmentosa, is a component of the Golgi-centrosomal network
Hum. Mol. Genet.
2015
24: 3359-3371
|
| 21738402 |
Mayinu et al.:
Evaluation of LOXL1 polymorphisms in exfoliation syndrome in the Uygur population
Mol. Vis.
2011
17: 1734-1744
|
| 28460050 |
Dharmat R et al.:
IFT81 as a Candidate Gene for Nonsyndromic Retinal Degeneration
Invest. Ophthalmol. Vis. Sci.
2017
58: 2483-2490
|
| 29978320 |
Chekuri A et al. et al.:
IFT88 mutations identified in individuals with non-syndromic recessive retinal degeneration result in abnormal ciliogenesis
Hum. Genet.
2018
137: 447-458
|
| 9356462 |
Tullio AN et al.:
Nonmuscle myosin II-B is required for normal development of the mouse heart
Proc. Natl. Acad. Sci. U.S.A.
1997
94
|
| 23028652 |
Schnatwinkel C et al.:
Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice
PLoS ONE
2012
7
|
| 31301482 |
Zhang J et al.:
Compound heterozygous mutations in SMO associated with anterior segment dysgenesis and morning glory syndrome
Gene
2019
713
|
| 21451052 |
Cwinn MA et al.:
Suppressor of fused is required to maintain the multipotency of neural progenitor cells in the retina
J. Neurosci.
2011
31: 5169-5180
|
| 28011711 |
Yu Y et al.:
Protective coding variants in CFH and PELI3 and a variant near CTRB1 are associated with age-related macular degenerationdagger
Hum. Mol. Genet.
2016
25: 5276-5285
|
| 31492759 |
Khouj EM et al.:
Differential requirements for the EF-hand domains of human centrin 2 in primary ciliogenesis and nucleotide excision repair
|
| 21850159 |
Orr A et al. et al.:
Mutations in a novel serine protease PRSS56 in families with nanophthalmos
Mol. Vis.
2011
17: 1850-1861
|
| 24227917 |
Jiang D et al.:
Evaluation of PRSS56 in Chinese subjects with high hyperopia or primary angle-closure glaucoma
Mol. Vis.
2013
19: 2217-2226
|
| 21282569 |
Li G et al.:
Role of miR-204 in the regulation of apoptosis, endoplasmic reticulum stress response, and inflammation in human trabecular meshwork cells
Invest. Ophthalmol. Vis. Sci.
2011
52: 2999-3007
|
| 31451908 |
Crespo-Garcia S et al.:
Lack of netrin-4 alters vascular remodeling in the retina
Graefes Arch. Clin. Exp. Ophthalmol.
2019
257: 2179-2184
|
| 18037624 |
Hewitt AW et al.:
Ancestral LOXL1 variants are associated with pseudoexfoliation in Caucasian Australians but with markedly lower penetrance than in Nordic people
Hum. Mol. Genet.
2008
17: 710-716
|
| 16938851 |
Hayashida Y et al. et al.:
Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O-sulfotransferase
Proc. Natl. Acad. Sci. U.S.A.
2006
103
|
| 21724832 |
Kim J et al.:
Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism
Genes Dev
2011
25: 1399-1411
|
| 17259973 |
Hellstrom M et al. et al.:
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
Nature
2007
445: 776-780
|
| 17296940 |
Lobov IB et al.:
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting
Proc Natl Acad Sci U S A
2007
104: 3219-3224
|
| 20036349 |
author information missing
article information missing
|
| 20046407 |
Kawashige S et al.:
An association study of the signal transducer and activator of transcription 6 gene with periodic psychosis
Psychiatry Investig
2008
5: 41-44
|
| 31616000 |
Guo H et al. et al.:
Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders
Nat Commun
2019
10: 4679
|
| 20237237 |
Ke Y et al.:
COMMD1 downregulates the epithelial sodium channel through Nedd4-2
Am. J. Physiol. Renal Physiol.
2010
298
|
| 16189295 |
Thomas CP et al.:
Medroxyprogesterone acetate binds the glucocorticoid receptor to stimulate alpha-ENaC and sgk1 expression in renal collecting duct epithelia
Am. J. Physiol. Renal Physiol.
2006
290: F306-F312
|
| 15640376 |
Ishiguro N et al.:
Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney
Drug Metab. Dispos.
2005
33: 495-499
|
| 12042308 |
Patrie KM et al.:
Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1
J. Biol. Chem.
2002
277
|
| 16885150 |
Zager RA et al.:
Toll-like receptor (TLR4) shedding and depletion: acute proximal tubular cell responses to hypoxic and toxic injury
Am. J. Physiol. Renal Physiol.
2007
292: F304-F312
|
| 30599068 |
Moujaber O et al.:
Cellular senescence is associated with reorganization of the microtubule cytoskeleton
Cell. Mol. Life Sci.
2019
76: 1169-1183
|
| 23547034 |
Bhatia K et al.:
Sex differences in angiotensin-converting enzyme modulation of Ang (1-7) levels in normotensive WKY rats
Am. J. Hypertens.
2013
26: 591-598
|
| 28478097 |
Haque F et al.:
Non-muscle myosin II deletion in the developing kidney causes ureter-bladder misconnection and apical extrusion of the nephric duct lineage epithelia
Dev. Biol.
2017
427: 121-130
|
| 19177153 |
Freedman BI et al.:
Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans
Kidney Int.
2009
75: 736-745
|
| 27122542 |
Koehler S et al.:
Par3A is dispensable for the function of the glomerular filtration barrier of the kidney
Am J Physiol Renal Physiol
2016
311: F112-F119
|
| 19506087 |
Cornish TC et al.:
Glomerular protein levels of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 are lower in diabetic subjects
J Histochem Cytochem
2009
57: 995-1001
|
| 26052839 |
Guo F et al.:
Lentiviral Vector-Mediated FoxO1 Overexpression Inhibits Extracellular Matrix Protein Secretion Under High Glucose Conditions in Mesangial Cells
J Cell Biochem
2016
117: 74-83
|
| 11801598 |
Kawata Y et al.:
bcn-1 Element-dependent activation of the laminin gamma 1 chain gene by the cooperative action of transcription factor E3 (TFE3) and Smad proteins
J Biol Chem
2002
277
|
| 16164642 |
Feliers D et al.:
VEGF regulation of endothelial nitric oxide synthase in glomerular endothelial cells
Kidney Int
2005
68: 1648-1659
|
| 29482391 |
Grgurevic L et al. et al.:
Systemic inhibition of BMP1-3 decreases progression of CCl4-induced liver fibrosis in rats
Growth Factors
2017
35: 201-215
|
| 17517249 |
Tanner LM et al.:
Nephropathy advancing to end-stage renal disease: a novel complication of lysinuric protein intolerance
J Pediatr
2007
150: 631-634
|
| 19211685 |
Wang W et al.:
Netrin-1 increases proliferation and migration of renal proximal tubular epithelial cells via the UNC5B receptor
Am J Physiol Renal Physiol
2009
296: F723-F729
|
| 23468852 |
Hsu YH et al.:
Interleukin-19 mediates tissue damage in murine ischemic acute kidney injury
PLoS One
2013
8
|
| 23295649 |
Satoh M et al.:
Angiostatin production increases in response to decreased nitric oxide in aging rat kidney
Lab Invest
2013
93: 334-343
|
| 22688335 |
Zhang MZ et al.:
Intrarenal dopamine inhibits progression of diabetic nephropathy
Diabetes
2012
61: 2575-2584
|
| 8675685 |
Cheng HF et al.:
Dopamine decreases expression of type-1 angiotensin II receptors in renal proximal tubule
J Clin Invest
1996
97: 2745-2752
|
| 29984779 |
Matsuyama T et al.:
The Relationship between the Intrarenal Dopamine System and Intrarenal Renin-angiotensin System Depending on the Renal Function
Intern Med
2018
57: 3241-3247
|
| 16394111 |
Zhang SX et al.:
Therapeutic potential of angiostatin in diabetic nephropathy
J Am Soc Nephrol
2006
17: 475-486
|
| 32381599 |
Laszczyk AM et al.:
Pax2 and Pax8 Proteins Regulate Urea Transporters and Aquaporins to Control Urine Concentration in the Adult Kidney
J Am Soc Nephrol
2020
31: 1212-1225
|
| 18222180 |
Lindner HA et al.:
N-acetylamino acid utilization by kidney aminoacylase-1
Biochimie
2008
90: 773-780
|
| 33176333 |
Kuppe C et al. et al.:
Decoding myofibroblast origins in human kidney fibrosis
|
| 28249836 |
Heuer JG et al.:
Role of TGF-alpha in the progression of diabetic kidney disease
Am J Physiol Renal Physiol
2017
312: F951-F962
|
| 15882257 |
Esposito C et al.:
Hepatocyte growth factor (HGF) modulates matrix turnover in human glomeruli
Kidney Int
2005
67: 2143-2150
|
| 25813703 |
Garcia-Martinez V et al.:
Sphingomyelin derivatives increase the frequency of microvesicle and granule fusion in chromaffin cells
Neuroscience
2015
295: 117-125
|
| 24073281 |
Garcia-Martinez V et al.:
Lipid metabolites enhance secretion acting on SNARE microdomains and altering the extent and kinetics of single release events in bovine adrenal chromaffin cells
PLoS One
2013
8
|
| 25949933 |
Choi MR et al.:
Renal dopaminergic system: Pathophysiological implications and clinical perspectives
World J Nephrol
2015
4: 196-212
|
| 18547994 |
Zeng C et al. et al.:
Renal D3 dopamine receptor stimulation induces natriuresis by endothelin B receptor interactions
Kidney Int
2008
74: 750-759
|
| 1979719 |
Bertorello A et al.:
Inhibition of proximal tubule Na(+)-K(+)-ATPase activity requires simultaneous activation of DA1 and DA2 receptors
Am J Physiol
1990
259: F924-F928
|
| 32259353 |
Tiu AC et al.:
Lipid rafts are required for effective renal D1 dopamine receptor function
FASEB J
2020
34: 6999-7017
|
| 22169008 |
Yang S et al.:
Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury
Am J Physiol Renal Physiol
2012
302: F742-F749
|
| 21701066 |
Zhang MZ et al.:
Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice
J Clin Invest
2011
121: 2845-2854
|
| 19139376 |
Zhang MZ et al.:
Intrarenal dopaminergic system regulates renin expression
Hypertension
2009
53: 564-570
|
| 19330604 |
Zeng C et al.:
Reactive oxygen species and dopamine receptor function in essential hypertension
Clin Exp Hypertens
2009
31: 156-178
|
| 15598876 |
Yang Z et al.:
D5 dopamine receptor regulation of phospholipase D
Am J Physiol Heart Circ Physiol
2005
288: H55-H61
|
| 18172057 |
Gildea JJ et al.:
Differential D1 and D5 receptor regulation and degradation of the angiotensin type 1 receptor
Hypertension
2008
51: 360-366
|
| 31411069 |
Banday AA et al.:
Kidney dopamine D1-like receptors and angiotensin 1-7 interaction inhibits renal Na(+) transporters
Am J Physiol Renal Physiol
2019
317: F949-F956
|
| 28560461 |
Wu Y et al.:
Increased SLC7A8 expression mediates L-DOPA uptake by renal tubular epithelial cells
Mol Med Rep
2017
16: 887-893
|
| 25368031 |
Chen K et al.:
Activation of D4 dopamine receptor decreases angiotensin II type 1 receptor expression in rat renal proximal tubule cells
Hypertension
2015
65: 153-160
|
| 31030607 |
Gildea JJ et al.:
The Dopamine D1 Receptor and Angiotensin II Type-2 Receptor are Required for Inhibition of Sodium Transport Through a Protein Phosphatase 2A Pathway
Hypertension
2019
73: 1258-1265
|
| 28768665 |
Hu MC et al.:
Dopamine reduces cell surface Na(+)/H(+) exchanger-3 protein by decreasing NHE3 exocytosis and cell membrane recycling
Am J Physiol Renal Physiol
2017
313
|
| 30808844 |
Taveira-da-Silva R et al.:
L-Tyr-Induced Phosphorylation of Tyrosine Hydroxylase at Ser40: An Alternative Route for Dopamine Synthesis and Modulation of Na+/K+-ATPase in Kidney Cells
Kidney Blood Press Res
2019
44: 1-11
|
| 9647500 |
Reddy S et al.:
Acute volume expansion and salt-loading studies in rats. The role of atrial natriuretic peptide and catecholamines
Nephron
1998
79: 192-200
|
| 16168010 |
De Luca Sarobe V et al.:
Low sodium intake induces an increase in renal monoamine oxidase activity in the rat. Involvement of an angiotensin II dependent mechanism
Acta Physiol Scand
2005
185: 161-167
|
| 24500688 |
Wang S et al. et al.:
Regulation of renalase expression by D5 dopamine receptors in rat renal proximal tubule cells
Am J Physiol Renal Physiol
2014
306: F588-F596
|
| 25411385 |
Quelhas-Santos J et al.:
Renalase regulates peripheral and central dopaminergic activities
Am J Physiol Renal Physiol
2015
308: F84-F91
|
| 23733636 |
Armando I et al.:
Dopamine and renal function and blood pressure regulation
Compr Physiol
2011
1: 1075-1117
|
| 10894789 |
Carranza A et al.:
L-Dopa uptake and dopamine production in proximal tubular cells are regulated by beta(2)-adrenergic receptors
Am J Physiol Renal Physiol
2000
279: F77-F83
|
| 11134247 |
Takezako T et al.:
Adenosine activates aromatic L-amino acid decarboxylase activity in the kidney and increases dopamine
J Am Soc Nephrol
2001
12: 29-36
|
| 17244889 |
Maurel A et al.:
Vesicular monoamine transporter 1 mediates dopamine secretion in rat proximal tubular cells
Am J Physiol Renal Physiol
2007
292
|
| 3161340 |
author information missing
Blockade of renal effects of dopamine in the dog by the DA1 antagonist SCH 23390
Am J Physiol
1985
249: F236-F240
|
| 11137859 |
Asghar M et al.:
Activation of dopamine D(1)-like receptor causes phosphorylation of alpha(1)-subunit of Na(+),K(+)-ATPase in rat renal proximal tubules
Eur J Pharmacol
2001
411: 61-66
|
| 8097567 |
Chen C et al.:
Inhibition of Na+,K(+)-ATPase in rat renal proximal tubules by dopamine involved DA-1 receptor activation
Naunyn Schmiedebergs Arch Pharmacol
1993
347: 289-295
|
| 32446726 |
Cao JY et al.:
Dopamine D1 receptor agonist A68930 attenuates acute kidney injury by inhibiting NLRP3 inflammasome activation
J Pharmacol Sci
2020
143: 226-233
|
| 25825816 |
Li F et al.:
Sorting nexin 5 and dopamine d1 receptor regulate the expression of the insulin receptor in human renal proximal tubule cells
Endocrinology
2015
156: 2211-2221
|
| 9691085 |
Asico LD et al.:
Disruption of the dopamine D3 receptor gene produces renin-dependent hypertension
J Clin Invest
1998
102: 493-498
|
| 18464932 |
Li H et al. et al.:
Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells
J Clin Invest
2008
118: 2180-2189
|
| 15699451 |
Zeng C et al.:
Interaction of angiotensin II type 1 and D5 dopamine receptors in renal proximal tubule cells
Hypertension
2005
45: 804-810
|
| 19293600 |
Choi MR et al.:
Angiotensin II regulation of renal dopamine uptake and Na(+),K(+)-ATPase activity
Nephron Physiol
2009
111: p53-p58
|
| 25770092 |
Yang S et al.:
Enhanced Natriuresis and Diuresis in Wistar Rats Caused by the Costimulation of Renal Dopamine D3 and Angiotensin II Type 2 Receptors
Am J Hypertens
2015
28: 1267-1276
|
| 24903104 |
Kemp BA et al.:
AT(2) receptor activation induces natriuresis and lowers blood pressure
Circ Res
2014
115: 388-399
|
| 16902178 |
Zeng C et al. et al.:
Activation of D3 dopamine receptor decreases angiotensin II type 1 receptor expression in rat renal proximal tubule cells
Circ Res
2006
99: 494-500
|
| 27780818 |
Jiang X et al.:
Gastrin stimulates renal dopamine production by increasing the renal tubular uptake of l-DOPA
Am J Physiol Endocrinol Metab
2017
312: E1-E10
|
| 26751218 |
Jiang X et al.:
The Synergistic Roles of Cholecystokinin B and Dopamine D5 Receptors on the Regulation of Renal Sodium Excretion
PLoS One
2016
11
|
| 24019399 |
Chen Y et al.:
Gastrin and D1 dopamine receptor interact to induce natriuresis and diuresis
Hypertension
2013
62: 927-933
|
| 12707290 |
Banday AA et al.:
Dopamine-mediated inhibition of renal Na,K-ATPase is reduced by insulin
Hypertension
2003
41: 1353-1358
|
| 16337875 |
Asghar M et al.:
Hydrogen peroxide causes uncoupling of dopamine D1-like receptors from G proteins via a mechanism involving protein kinase C and G-protein-coupled receptor kinase 2
Free Radic Biol Med
2006
40: 13-20
|
| 25870190 |
Yang J et al.:
G protein-coupled receptor kinase 4: role in hypertension
Hypertension
2015
65: 1148-1155
|
| 22123211 |
Harris RC et al.:
Abnormalities in renal dopamine signaling and hypertension: the role of GRK4
Curr Opin Nephrol Hypertens
2012
21: 61-65
|
| 19520868 |
Villar VA et al.:
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor
J Biol Chem
2009
284
|
| 24552847 |
Gildea JJ et al.:
The cooperative roles of the dopamine receptors, D1R and D5R, on the regulation of renal sodium transport
Kidney Int
2014
86: 118-126
|
| 32349533 |
Yang J et al.:
Renal Dopamine Receptors and Oxidative Stress: Role in Hypertension
|
| 25339698 |
Ennis RC et al.:
Dopamine D(1)-like receptors regulate the alpha(1)A-adrenergic receptor in human renal proximal tubule cells and D(1)-like dopamine receptor knockout mice
Am J Physiol Renal Physiol
2014
307
|
| 25562528 |
Pokkunuri I et al.:
Age-related hypertension and salt sensitivity are associated with unique cortico-medullary distribution of D1R, AT1R, and NADPH-oxidase in FBN rats
Clin Exp Hypertens
2015
37: 1-7
|
| 29654295 |
Armando I et al.:
Antihypertensive effect of etamicastat in dopamine D2 receptor-deficient mice
Hypertens Res
2018
41: 489-498
|
| 20810614 |
Wang X et al.:
Reduction of renal dopamine receptor expression in obese Zucker rats: role of sex and angiotensin II
Am J Physiol Renal Physiol
2010
299
|
| 24308971 |
Armando I et al.:
Dopamine D3 receptor inhibits the ubiquitin-specific peptidase 48 to promote NHE3 degradation
FASEB J
2014
28: 1422-1434
|
| 15265811 |
Pedrosa R et al.:
Dopamine D3 receptor-mediated inhibition of Na+/H+ exchanger activity in normotensive and spontaneously hypertensive rat proximal tubular epithelial cells
Br J Pharmacol
2004
142: 1343-1353
|
| 28230199 |
Tang L et al.:
Activation of angiotensin II type 1 receptors increases D4 dopamine receptor expression in rat renal proximal tubule cells
Hypertens Res
2017
40: 652-657
|
| 27107134 |
Zhang Y et al.:
Inhibition of D4 Dopamine Receptors on Insulin Receptor Expression and Effect in Renal Proximal Tubule Cells
|
| 23985827 |
Cuevas S et al.:
Renal dopamine receptors, oxidative stress, and hypertension
Int J Mol Sci
2013
14
|
| 25740199 |
Yang S et al.:
Dopamine D1 and D5 receptors differentially regulate oxidative stress through paraoxonase 2 in kidney cells
Free Radic Res
2015
49: 397-410
|
| 8569088 |
Rovin BH et al.:
Activation of nuclear factor-kappa B correlates with MCP-1 expression by human mesangial cells
Kidney Int
1995
48: 1263-1271
|
| 33464168 |
Yanes Cardozo LL et al.:
Androgens, the kidney, and COVID-19: an opportunity for translational research
Am J Physiol Renal Physiol
2021
320: F243-F248
|
| 32564694 |
Ji H et al.:
Sex-Specific Modulation of Blood Pressure and the Renin-Angiotensin System by ACE (Angiotensin-Converting Enzyme) 2
Hypertension
2020
76: 478-487
|
| 21208466 |
Liu J et al.:
Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17beta-oestradiol-dependent and sex chromosome-independent
Biol Sex Differ
2010
1: 6
|
| 23535224 |
Roberts MA et al.:
Angiotensin-converting enzyme 2 activity in patients with chronic kidney disease
Nephrol Dial Transplant
2013
28: 2287-2294
|
| 15538735 |
Lely AT et al.:
Renal ACE2 expression in human kidney disease
J Pathol
2004
204: 587-593
|
| 32662161 |
Hardenberg JB et al.:
Covid-19, ACE2 and the kidney
Acta Physiol (Oxf)
2020
230
|
| 32236644 |
Pan XW et al.:
Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis
Intensive Care Med
2020
46: 1114-1116
|
| 15841186 |
Crowley SD et al.:
Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system
J Clin Invest
2005
115: 1092-1099
|
| 22288735 |
Bernardi S et al. et al.:
Angiotensin-converting enzyme 2 regulates renal atrial natriuretic peptide through angiotensin-(1-7)
Clin Sci (Lond)
2012
123: 29-37
|
| 21593187 |
Banday AA et al.:
Angiotensin II-mediated biphasic regulation of proximal tubular Na+/H+ exchanger 3 is impaired during oxidative stress
Am J Physiol Renal Physiol
2011
301: F364-F370
|
| 3281475 |
Gomez RA et al.:
Renin and angiotensinogen gene expression in maturing rat kidney
Am J Physiol
1988
254: F582-F587
|
| 15888567 |
Kobori H et al.:
Enhanced intrarenal angiotensinogen contributes to early renal injury in spontaneously hypertensive rats
J Am Soc Nephrol
2005
16: 2073-2080
|
| 7584919 |
Shinagawa T et al.:
Role of cathepsin B as prorenin processing enzyme in human kidney
Hypertens Res
1995
18: 131-136
|
| 15534073 |
Siragy HM et al.:
Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation
Hypertension
2005
45: 133-137
|
| 33234728 |
Song J et al.:
Expression profiles revealed potential kidney injury caused by SARS-CoV-2: a systematic analysis of ACE2 and clinical lessons learned from this discovery
|
| 32660970 |
Sharma P et al.:
COVID-19-Associated Kidney Injury: A Case Series of Kidney Biopsy Findings
J Am Soc Nephrol
2020
31: 1948-1958
|
| 8023970 |
Tufro-McReddie A et al.:
Angiotensin II type 1 receptor: role in renal growth and gene expression during normal development
Am J Physiol
1994
266: F911-F918
|
| 14583438 |
Klar J et al.:
Aldosterone enhances renin gene expression in juxtaglomerular cells
Am J Physiol Renal Physiol
2004
286: F349-F355
|
| 12045255 |
Nguyen G et al.:
Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
J Clin Invest
2002
109: 1417-1427
|
| 22535800 |
Zhang J et al.:
Receptor-mediated nonproteolytic activation of prorenin and induction of TGF-beta1 and PAI-1 expression in renal mesangial cells
Am J Physiol Renal Physiol
2012
303: F11-F20
|
| 23698123 |
Lu X et al.:
(Pro)renin receptor is required for prorenin-dependent and -independent regulation of vacuolar H(+)-ATPase activity in MDCK.C11 collecting duct cells
Am J Physiol Renal Physiol
2013
305: F417-F425
|
| 27000064 |
Wang F et al.:
Antidiuretic Action of Collecting Duct (Pro)Renin Receptor Downstream of Vasopressin and PGE2 Receptor EP4
J Am Soc Nephrol
2016
27: 3022-3034
|
| 18413493 |
Kang JJ et al.:
The collecting duct is the major source of prorenin in diabetes
Hypertension
2008
51: 1597-1604
|
| 24866147 |
Wang F et al.:
Prostaglandin E-prostanoid4 receptor mediates angiotensin II-induced (pro)renin receptor expression in the rat renal medulla
Hypertension
2014
64: 369-377
|
| 21325494 |
Li C et al.:
Molecular mechanisms of angiotensin II stimulation on aquaporin-2 expression and trafficking
Am J Physiol Renal Physiol
2011
300
|
| 27228084 |
Ohashi N et al. et al.:
Plasma Soluble (Pro)renin Receptor Reflects Renal Damage
PLoS One
2016
11
|
| 22301996 |
Ichihara A et al.:
(Pro)renin receptor and autophagy in podocytes
Autophagy
2012
8: 271-272
|
| 26984496 |
Lu X et al.:
Soluble (pro)renin receptor via beta-catenin enhances urine concentration capability as a target of liver X receptor
Proc Natl Acad Sci U S A
2016
113
|
| 19380613 |
Cousin C et al.:
Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma
Hypertension
2009
53: 1077-1082
|
| 28903918 |
Fang H et al.:
(Pro)renin receptor mediates albumin-induced cellular responses: role of site-1 protease-derived soluble (pro)renin receptor in renal epithelial cells
Am J Physiol Cell Physiol
2017
313: C632-C643
|
| 19174157 |
He M et al.:
Inhibition of renin/prorenin receptor attenuated mesangial cell proliferation and reduced associated fibrotic factor release
Eur J Pharmacol
2009
606: 155-161
|
| 24601883 |
Saito S et al.:
Indoxyl sulfate-induced activation of (pro)renin receptor is involved in expression of TGF-beta1 and alpha-smooth muscle actin in proximal tubular cells
Endocrinology
2014
155: 1899-1907
|
| 19451703 |
Melnyk RA et al.:
Renin and prorenin activate pathways implicated in organ damage in human mesangial cells independent of angiotensin II production
Am J Nephrol
2009
30: 232-243
|
| 9556572 |
Ludwig J et al.:
Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules
J Biol Chem
1998
273
|
| 28814438 |
Prieto MC et al. et al.:
Collecting duct prorenin receptor knockout reduces renal function, increases sodium excretion, and mitigates renal responses in ANG II-induced hypertensive mice
Am J Physiol Renal Physiol
2017
313
|
| 11960999 |
Peti-Peterdi J et al.:
Angiotensin II directly stimulates ENaC activity in the cortical collecting duct via AT(1) receptors
J Am Soc Nephrol
2002
13: 1131-1135
|
| 33713620 |
Yeung ML et al. et al.:
Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system
|
| 23407646 |
Carey RM et al.:
The intrarenal renin-angiotensin and dopaminergic systems: control of renal sodium excretion and blood pressure
Hypertension
2013
61: 673-680
|
| 16380540 |
Padia SH et al.:
Renal angiotensin type 2 receptors mediate natriuresis via angiotensin III in the angiotensin II type 1 receptor-blocked rat
Hypertension
2006
47: 537-544
|
| 22710646 |
Gildea JJ et al.:
Dopamine and angiotensin type 2 receptors cooperatively inhibit sodium transport in human renal proximal tubule cells
Hypertension
2012
60: 396-403
|
| 18158338 |
Padia SH et al.:
Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats
Hypertension
2008
51: 460-465
|
| 22689743 |
Kemp BA et al.:
Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors
Hypertension
2012
60: 387-395
|
| 16754789 |
Abadir PM et al.:
Angiotensin II type 2 receptor-bradykinin B2 receptor functional heterodimerization
Hypertension
2006
48: 316-322
|
| 12953015 |
Abadir PM et al.:
Angiotensin AT2 receptors directly stimulate renal nitric oxide in bradykinin B2-receptor-null mice
Hypertension
2003
42: 600-604
|
| 10334818 |
Siragy HM et al.:
Protective role of the angiotensin AT2 receptor in a renal wrap hypertension model
Hypertension
1999
33: 1237-1242
|
| 19262461 |
Pinheiro SVB et al. et al.:
Genetic deletion of the angiotensin-(1-7) receptor Mas leads to glomerular hyperfiltration and microalbuminuria
Kidney Int
2009
75: 1184-1193
|
| 32247631 |
Cheng Y et al.:
Kidney disease is associated with in-hospital death of patients with COVID-19
Kidney Int
2020
97: 829-838
|
| 33125431 |
Maksimowski N et al.:
Kidney ACE2 expression: Implications for chronic kidney disease
PLoS One
2020
15
|
| 32418507 |
Kaltenecker CC et al. et al.:
Critical Role of Neprilysin in Kidney Angiotensin Metabolism
Circ Res
2020
127: 593-606
|
| 15034162 |
Sanders JS et al.:
Renal expression of matrix metalloproteinases in human ANCA-associated glomerulonephritis
Nephrol Dial Transplant
2004
19: 1412-1419
|
| 8613196 |
Troyanovskaya M et al.:
Expression of aminopeptidase A, an angiotensinase, in glomerular mesangial cells
Hypertension
1996
27: 518-522
|
| 1354270 |
Stefanovic V et al.:
Cell surface aminopeptidase A and N activities in human glomerular epithelial cells
Kidney Int
1992
41: 1571-1580
|
| 15177935 |
De Souza AM et al.:
Angiotensin II and angiotensin-(1-7) inhibit the inner cortex Na+ -ATPase activity through AT2 receptor
Regul Pept
2004
120: 167-175
|
| 20689424 |
Bolignano D et al.:
Vasopressin beyond water: implications for renal diseases
Curr Opin Nephrol Hypertens
2010
19: 499-504
|
| 29556787 |
Szczepanska-Sadowska E et al.:
Dysregulation of the Renin-Angiotensin System and the Vasopressinergic System Interactions in Cardiovascular Disorders
Curr Hypertens Rep
2018
20: 19
|
| 20032116 |
Zhang J et al.:
Infusion of angiotensin-(1-7) reduces glomerulosclerosis through counteracting angiotensin II in experimental glomerulonephritis
Am J Physiol Renal Physiol
2010
298: F579-F588
|
| 20478903 |
Bahiense-Oliveira M et al.:
Interstitial expression of angiotensin II and AT1 receptor are increased in patients with progressive glomerulopathies
J Renin Angiotensin Aldosterone Syst
2010
11: 158-164
|
| 33824491 |
Prieto MC et al.:
The evolving complexity of the collecting duct renin-angiotensin system in hypertension
|
| 14534790 |
Magaldi AJ et al.:
Angiotensin-(1-7) stimulates water transport in rat inner medullary collecting duct: evidence for involvement of vasopressin V2 receptors
Pflugers Arch
2003
447: 223-230
|
| 17634404 |
Kotlo K et al.:
Aminopeptidase N reduces basolateral Na+ -K+ -ATPase in proximal tubule cells
Am J Physiol Renal Physiol
2007
293
|
| 32865015 |
Xie S et al.:
Soluble (pro)renin receptor promotes the fibrotic response in renal proximal tubule epithelial cells in vitro via the Akt/beta-catenin/Snail signaling pathway
Am J Physiol Renal Physiol
2020
319: F941-F953
|
| 26995300 |
Simoes E Silva AC et al.:
ACE inhibition, ACE2 and angiotensin-(1-7) axis in kidney and cardiac inflammation and fibrosis
Pharmacol Res
2016
107: 154-162
|
| 24429398 |
Hwang DY et al.:
Mutations in 12 known dominant disease-causing genes clarify many congenital anomalies of the kidney and urinary tract
Kidney Int
2014
85: 1429-1433
|
| 9598309 |
Groenen PM et al.:
Rearrangement of the human CDC5L gene by a t(6;19)(p21;q13.1) in a patient with multicystic renal dysplasia
Genomics
1998
49: 218-229
|
| 32179955 |
Liu C et al.:
Aquaporin 1 alleviates acute kidney injury via PI3K-mediated macrophage M2 polarization
Inflamm Res
2020
69: 509-521
|
| 11848284 |
author information missing
article information missing
|
| 29653693 |
author information missing
article information missing
|
| 23739232 |
author information missing
article information missing
|
| 33838163 |
author information missing
article information missing
|
| 10662705 |
author information missing
article information missing
|
| 27770286 |
author information missing
article information missing
|
| 20567872 |
author information missing
article information missing
|
| 26986757 |
author information missing
article information missing
|
| 33575899 |
author information missing
article information missing
|
| 7947028 |
author information missing
article information missing
|
| 21613803 |
author information missing
article information missing
|
| 34548389 |
author information missing
article information missing
|
| 19634143 |
author information missing
article information missing
|
| 32062662 |
author information missing
article information missing
|
| 16889043 |
author information missing
article information missing
|
| 17449492 |
author information missing
article information missing
|
| 31988269 |
author information missing
article information missing
|
| 29031353 |
author information missing
article information missing
|
| 20370926 |
Tatebe K et al.:
Response network analysis of differential gene expression in human epithelial lung cells during avian influenza infections.
BMC Bioinformatics
2010
11: 170
|
| 25355440 |
Kimura S et al.:
A novel type of cells expressing GP2 in the respiratory epithelium of the paranasal sinuses in mice
Biomed. Res.
2014
35: 329-337
|
| 31089908 |
Schouten LR et al. et al.:
Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study
Ann Intensive Care
2019
9: 55
|
| 24929828 |
Loth DW et al. et al.:
Genome-wide association analysis identifies six new loci associated with forced vital capacity
Nat. Genet.
2014
46: 669-677
|
| 32537478 |
Saheb Sharif-Askari N et al.:
Airways Expression of SARS-CoV-2 Receptor, ACE2, and TMPRSS2 Is Lower in Children Than Adults and Increases with Smoking and COPD
Mol Ther Methods Clin Dev
2020
18: 1-6
|
| 32633718 |
Garvin MR et al.:
A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm
|
| 230781 |
author information missing
Familial subacute necrotizing encephalomyelopathy of the adult form (adult Leigh syndrome)
Ann. Neurol.
1979
6: 200-206
|
| 28983317 |
author information missing
article information missing
|
| 21883220 |
Cao XH et al.:
Diabetic neuropathy enhances voltage-activated Ca2+ channel activity and its control by M4 muscarinic receptors in primary sensory neurons
J. Neurochem.
2011
119: 594-603
|
| 20085713 |
Okamoto K et al.:
Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus
Am. J. Hum. Genet.
2010
86: 54-64
|
| 22235116 |
Mosedale M et al.:
Neurexin-1alpha contributes to insulin-containing secretory granule docking
J. Biol. Chem.
2012
287: 6350-6361
|
| 23036710 |
Manoel-Caetano FS et al.:
Gene expression profiles displayed by peripheral blood mononuclear cells from patients with type 2 diabetes mellitus focusing on biological processes implicated on the pathogenesis of the disease
Gene
2012
511: 151-160
|
| 19538749 |
Pavlinkova G et al.:
Maternal diabetes alters transcriptional programs in the developing embryo
BMC Genomics
2009
10: 274
|
| 26778897 |
Sas KM et al.:
Targeted Lipidomic and Transcriptomic Analysis Identifies Dysregulated Renal Ceramide Metabolism in a Mouse Model of Diabetic Kidney Disease
|
| 33505018 |
Ansarullah et al. et al.:
Inceptor counteracts insulin signalling in beta-cells to control glycaemia
|
| 28323968 |
author information missing
article information missing
|
| 22337556 |
author information missing
article information missing
|
| 2328638 |
et al.:
Post-MI patients perceptions of their learning needs
Dimens Crit Care Nurs
1990
9: 112-118
|
| 30561643 |
Lahola-Chomiak AA et al. et al.:
Non-Synonymous variants in premelanosome protein (PMEL) cause ocular pigment dispersion and pigmentary glaucoma
Hum. Mol. Genet.
2019
28: 1298-1311
|
| 11406612 |
Sittler A et al.:
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntingtons disease.
Hum. Mol. Genet.
2001
10: 1307-1315
|
| 11739625 |
Jeitner TM et al.:
N(epsilon)-(gamma-L-glutamyl)-L-lysine (GGEL) is increased in cerebrospinal fluid of patients with Huntingtons disease
J. Neurochem.
2001
79: 1109-1112
|
| 19076431 |
Johnson JA et al.:
The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration
Ann. N. Y. Acad. Sci.
2008
1147: 61-69
|
| 20451497 |
Sinha M et al.:
Altered microRNAs in STHdh(Q111)/Hdh(Q111) cells: miR-146a targets TBP
Biochem. Biophys. Res. Commun.
2010
396: 742-747
|
| 18167354 |
Doi H et al.:
RNA-binding protein TLS is a major nuclear aggregate-interacting protein in huntingtin exon 1 with expanded polyglutamine-expressing cells
J. Biol. Chem.
2008
283: 6489-6500
|
| 19218238 |
Iwata A et al.:
Intranuclear degradation of polyglutamine aggregates by the ubiquitin-proteasome system
J. Biol. Chem.
2009
284: 9796-9803
|
| 29351877 |
Hwang JY et al.:
REST, a master transcriptional regulator in neurodegenerative disease
Curr. Opin. Neurobiol.
2018
48: 193-200
|
| 26968346 |
Martini-Stoica H et al.:
The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective
Trends Neurosci.
2016
39: 221-234
|
| 24705354 |
Butland SL et al.:
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntingtons disease
Hum. Mol. Genet.
2014
23: 4142-4160
|
| 17055784 |
Weydt P et al. et al.:
Thermoregulatory and metabolic defects in Huntingtons disease transgenic mice implicate PGC-1alpha in Huntingtons disease neurodegeneration
Cell Metab.
2006
4: 349-362
|
| 27107943 |
Lin L et al.:
Atypical ubiquitination by E3 ligase WWP1 inhibits the proteasome-mediated degradation of mutant huntingtin
Brain Res.
2016
1643: 103-112
|
| 30122542 |
Long JD et al.:
Genetic Modification of Huntington Disease Acts Early in the Prediagnosis Phase
Am. J. Hum. Genet.
2018
103: 349-357
|
| 30358836 |
Goold R et al.:
FAN1 modifies Huntingtons disease progression by stabilizing the expanded HTT CAG repeat
Hum. Mol. Genet.
2019
28: 650-661
|
| 26232222 |
Zhao XN et al.:
FAN1 protects against repeat expansions in a Fragile X mouse model
DNA Repair (Amst.)
2018
69: 1-5
|
| 25941073 |
Narayanan KL et al.:
Rho Kinase Pathway Alterations in the Brain and Leukocytes in Huntingtons Disease
Mol. Neurobiol.
2016
53: 2132-2140
|
| 18573880 |
Shao J et al.:
Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation
Mol. Cell. Biol.
2008
28: 5196-5208
|
| 9139462 |
author information missing
[Endorphins and neurotensin in Huntington chorea]
Vopr. Med. Khim.
1996
42: 263-267
|
| 29453932 |
Gomez-Pineda VG et al.:
Neurotrophin-3 restores synaptic plasticity in the striatum of a mouse model of Huntingtons disease
CNS Neurosci Ther
2018
24: 353-363
|
| 29480208 |
Tsuang DW et al.:
A Genetic Study of Psychosis in Huntingtons Disease: Evidence for the Involvement of Glutamate Signaling Pathways
J Huntingtons Dis
2018
7: 51-59
|
| 9700202 |
Faber PW et al.:
Huntingtin interacts with a family of WW domain proteins
Hum. Mol. Genet.
1998
7: 1463-1474
|
| 29121340 |
Ehrnhoefer DE et al. et al.:
HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo
Hum. Mol. Genet.
2018
27: 239-253
|
| 34721539 |
author information missing
article information missing
|
| 37005488 |
author information missing
article information missing
|
| 24121255 |
author information missing
article information missing
|
| 8702625 |
author information missing
article information missing
|
| 18079691 |
Leveziel N et al.:
PLEKHA1-LOC387715-HTRA1 polymorphisms and exudative age-related macular degeneration in the French population
Mol Vis
2007
13: 2153-2159
|
| 22922256 |
Beedle AM et al.:
Mouse fukutin deletion impairs dystroglycan processing and recapitulates muscular dystrophy
J. Clin. Invest.
2012
122: 3330-3342
|
| 10189375 |
Crosbie RH et al.:
Membrane targeting and stabilization of sarcospan is mediated by the sarcoglycan subcomplex
J. Cell Biol.
1999
145: 153-165
|
| 14623885 |
Albrecht DE et al.:
DAMAGE, a novel alpha-dystrobrevin-associated MAGE protein in dystrophin complexes
J Biol Chem
2004
279: 7014-7023
|
| 34648194 |
author information missing
article information missing
|
| 23830518 |
author information missing
article information missing
|
| 24816431 |
Park MH et al.:
Recessive C10orf2 mutations in a family with infantile-onset spinocerebellar ataxia, sensorimotor polyneuropathy, and myopathy
Neurogenetics
2014
15: 171-182
|
| 27239408 |
Polge C et al.:
UBE2B is implicated in myofibrillar protein loss in catabolic C2C12 myotubes
J Cachexia Sarcopenia Muscle
2016
7: 377-387
|
| 31455395 |
Lornage X et al. et al.:
Clinical, histological, and genetic characterization of PYROXD1-related myopathy
Acta Neuropathol Commun
2019
7: 138
|
| 30515627 |
Sainio MT et al. et al.:
Recessive PYROXD1 mutations cause adult-onset limb-girdle-type muscular dystrophy
J. Neurol.
2019
266: 353-360
|
| 22522446 |
Edvardson S et al.:
Hereditary sensory autonomic neuropathy caused by a mutation in dystonin
Ann. Neurol.
2012
71: 569-572
|
| 26722758 |
Oikari LE et al.:
Cell surface heparan sulfate proteoglycans as novel markers of human neural stem cell fate determination
Stem Cell Res
2016
16: 92-104
|
| 15485858 |
Hogan A et al.:
The phosphoinositol 3,4-bisphosphate-binding protein TAPP1 interacts with syntrophins and regulates actin cytoskeletal organization
J Biol Chem
2004
279
|
| 26257172 |
author information missing
article information missing
|
| 18775955 |
Hakonen AH et al.:
Infantile-onset spinocerebellar ataxia and mitochondrial recessive ataxia syndrome are associated with neuronal complex I defect and mtDNA depletion
Hum. Mol. Genet.
2008
17: 3822-3835
|
| 12070658 |
Duda JE et al.:
Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred
Acta Neuropathol.
2002
104: 7-11
|
| 12714745 |
Giasson BI et al.:
Initiation and synergistic fibrillization of tau and alpha-synuclein
Science
2003
300: 636-640
|
| 12446971 |
Sanchez MP et al.:
Progressive supranuclear palsy and tau hyperphosphorylation in a patient with a C212Y parkin mutation
J. Alzheimers Dis.
2002
4: 399-404
|
| 19915575 |
Simon-Sanchez J et al. et al.:
Genome-wide association study reveals genetic risk underlying Parkinsons disease
Nat. Genet.
2009
41: 1308-1312
|
| 14705119 |
Rizzu P et al.:
DJ-1 colocalizes with tau inclusions: a link between parkinsonism and dementia.
Ann. Neurol.
2004
55: 113-118
|
| 16115732 |
Nishinaga H et al.:
Expression profiles of genes in DJ-1-knockdown and L 166 P DJ-1 mutant cells.
Neurosci. Lett.
2005
390: 54-59
|
| 24395787 |
Arif M et al.:
Tau pathology involves protein phosphatase 2A in parkinsonism-dementia of Guam
Proc. Natl. Acad. Sci. U.S.A.
2014
111: 1144-1149
|
| 15741239 |
Cammisotto PG et al.:
Regulation of leptin secretion from white adipocytes by insulin, glycolytic substrates, and amino acids
Am. J. Physiol. Endocrinol. Metab.
2005
289: E166-E171
|
| 14688247 |
Balbis A et al.:
Effect of inhibiting vacuolar acidification on insulin signaling in hepatocytes
J. Biol. Chem.
2004
279
|
| 15351740 |
Kang D et al.:
Functional expression of TREK-2 in insulin-secreting MIN6 cells
Biochem. Biophys. Res. Commun.
2004
323: 323-331
|
| 23349502 |
Abe T et al.:
Cbl-b is a critical regulator of macrophage activation associated with obesity-induced insulin resistance in mice
Diabetes
2013
62: 1957-1969
|
| 25064125 |
Xiao F et al.:
Central prolactin receptors (PRLRs) regulate hepatic insulin sensitivity in mice via signal transducer and activator of transcription 5 (STAT5) and the vagus nerve
Diabetologia
2014
57: 2136-2144
|
| 24068386 |
Nomura M et al.:
SMAD2 disruption in mouse pancreatic beta cells leads to islet hyperplasia and impaired insulin secretion due to the attenuation of ATP-sensitive K+ channel activity
Diabetologia
2014
57: 157-166
|
| 25008241 |
Mendez-Gimenez L et al.:
Role of aquaglyceroporins and caveolins in energy and metabolic homeostasis
|
| 27322467 |
Ding Y et al.:
Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis
EBioMedicine
2016
7: 135-145
|
| 29959129 |
Li Z et al.:
Inhibition of Epidermal Growth Factor Receptor Activation Is Associated With Improved Diabetic Nephropathy and Insulin Resistance in Type 2 Diabetes
Diabetes
2018
67: 1847-1857
|
| 31137828 |
author information missing
article information missing
|
| 20960553 |
author information missing
article information missing
|
| 29369529 |
author information missing
article information missing
|
| 22563043 |
author information missing
article information missing
|
| 2567958 |
author information missing
article information missing
|
| 29239245 |
author information missing
article information missing
|
| 28714900 |
Dongiovanni P et al.:
A Nutrigenomic Approach to Non-Alcoholic Fatty Liver Disease
|
| 908147 |
et al.:
The conversion of D-xylose into D-threitol in patients without liver disease and in patients with portal liver cirrhosis
Clin. Chim. Acta
1977
80: 49-54
|
| 23102618 |
Bayeva M et al.:
mTOR regulates cellular iron homeostasis through tristetraprolin
Cell Metab.
2012
16: 645-657
|
| 21781943 |
Song M et al.:
High fructose feeding induces copper deficiency in Sprague-Dawley rats: a novel mechanism for obesity related fatty liver
J. Hepatol.
2012
56: 433-440
|
| 19291785 |
Miele L et al.:
Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease
Hepatology
2009
49: 1877-1887
|
| 24456734 |
Wang LJ et al.:
Betaine attenuates hepatic steatosis by reducing methylation of the MTTP promoter and elevating genomic methylation in mice fed a high-fat diet
J. Nutr. Biochem.
2014
25: 329-336
|
| 26807955 |
Lu S et al.:
Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway
PLoS ONE
2016
11
|
| 29134411 |
Feldbrugge L et al.:
Distinct roles of ecto-nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) in liver regeneration and fibrosis
Purinergic Signal.
2018
14: 37-46
|
| 30221089 |
Hajighasem A et al.:
Effects of resveratrol, exercises and their combination on Farnesoid X receptor, Liver X receptor and Sirtuin 1 gene expression and apoptosis in the liver of elderly rats with nonalcoholic fatty liver
PeerJ
2018
6: e5522
|
| 28133767 |
von Loeffelholz C et al. et al.:
The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism
Hepatology
2017
66: 616-630
|
| 31926204 |
Cai Q et al.:
Epigenetic silencing of microRNA-125b-5p promotes liver fibrosis in nonalcoholic fatty liver disease via integrin alpha8-mediated activation of RhoA signaling pathway
Metab. Clin. Exp.
2020
104
|
| 32520409 |
author information missing
article information missing
|
| 21979151 |
author information missing
article information missing
|
| 24211299 |
author information missing
article information missing
|
| 22179204 |
author information missing
article information missing
|
| 36243100 |
author information missing
article information missing
|
| 27732084 |
author information missing
article information missing
|
| 30744560 |
author information missing
article information missing
|
| 26473743 |
author information missing
article information missing
|
| 27995398 |
Riley LG et al.:
A SLC39A8 variant causes manganese deficiency, and glycosylation and mitochondrial disorders
J. Inherit. Metab. Dis.
2017
40: 261-269
|
| 18424601 |
Konstantinova SV et al.:
Divergent associations of plasma choline and betaine with components of metabolic syndrome in middle age and elderly men and women
J. Nutr.
2008
138: 914-920
|
| 16365106 |
author information missing
article information missing
|
| 30697368 |
author information missing
article information missing
|
| 34801968 |
author information missing
article information missing
|
| 30830468 |
author information missing
article information missing
|
| 33360505 |
author information missing
article information missing
|
| 24832990 |
author information missing
article information missing
|
| 35013990 |
author information missing
article information missing
|
| 23275373 |
author information missing
article information missing
|
| 29895440 |
author information missing
article information missing
|
| 30611573 |
author information missing
article information missing
|
| 26996629 |
author information missing
article information missing
|
| 24144057 |
author information missing
article information missing
|
| 31479998 |
author information missing
article information missing
|
| 32197513 |
author information missing
article information missing
|
| 26709969 |
author information missing
article information missing
|
| 17053429 |
author information missing
article information missing
|
| 22399527 |
author information missing
article information missing
|
| 34630148 |
author information missing
article information missing
|
| 32733621 |
author information missing
article information missing
|
| 30186675 |
author information missing
article information missing
|
| 24695116 |
author information missing
article information missing
|
| 34149613 |
author information missing
article information missing
|
| 31133529 |
author information missing
article information missing
|
| 24710945 |
author information missing
article information missing
|
| 36145054 |
author information missing
article information missing
|
| 24650495 |
author information missing
article information missing
|
| 31601483 |
author information missing
article information missing
|
| 27070805 |
author information missing
article information missing
|
| 26408941 |
author information missing
article information missing
|
| 29075976 |
author information missing
article information missing
|
| 28094011 |
author information missing
article information missing
|
| 35058883 |
author information missing
article information missing
|
| 22553379 |
author information missing
article information missing
|
| 29165132 |
author information missing
article information missing
|
| 28958693 |
author information missing
article information missing
|
| 21378565 |
author information missing
article information missing
|
| 11111093 |
author information missing
article information missing
|
| 35743227 |
author information missing
article information missing
|
| 8597585 |
author information missing
article information missing
|
| 7744831 |
author information missing
article information missing
|
| 8016111 |
author information missing
article information missing
|
| 9195924 |
author information missing
article information missing
|
| 10593936 |
author information missing
article information missing
|
| 9687543 |
author information missing
article information missing
|
| 5009446 |
author information missing
article information missing
|
| 15834125 |
author information missing
article information missing
|
| 28446761 |
author information missing
article information missing
|
| 24458708 |
author information missing
article information missing
|
| 16354105 |
author information missing
article information missing
|
| 17495604 |
author information missing
article information missing
|
| 29277345 |
author information missing
article information missing
|
| 16309370 |
author information missing
article information missing
|
| 26460076 |
author information missing
article information missing
|
| 27110687 |
author information missing
article information missing
|
| 24315825 |
author information missing
article information missing
|
| 24889630 |
author information missing
article information missing
|
| 28411170 |
author information missing
article information missing
|
| 19439193 |
author information missing
article information missing
|
| 28324037 |
author information missing
article information missing
|
| 15476449 |
author information missing
article information missing
|
| 22115172 |
author information missing
article information missing
|
| 27422507 |
author information missing
article information missing
|
| 32079087 |
author information missing
article information missing
|
| 21593202 |
author information missing
article information missing
|
| 35956105 |
author information missing
article information missing
|
| 29212154 |
author information missing
article information missing
|
| 20164329 |
Gerard M et al.:
Inhibition of FK506 binding proteins reduces alpha-synuclein aggregation and Parkinsons disease-like pathology.
J. Neurosci.
2010
30: 2454-2463
|
| 20185556 |
Smith WW et al.:
Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model
Hum. Mol. Genet.
2010
19: 2087-2098
|
| 20523059 |
Kitamura F et al.:
Selective down-regulation of Th2 cytokines by C-terminal binding protein 2 in human T cells
Int. Arch. Allergy Immunol.
2010
152: 18-21
|
| 10438528 |
Holmes M et al.:
hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation
J. Biol. Chem.
1999
274
|
| 9724649 |
Turner J et al.:
Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators
EMBO J.
1998
17: 5129-5140
|
| 12101226 |
Hildebrand JD et al.:
Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development
Mol. Cell. Biol.
2002
22: 5296-5307
|
| 19798104 |
Kovi RC et al.:
An ARF/CtBP2 complex regulates BH3-only gene expression and p53-independent apoptosis
Cell Death Differ.
2010
17: 513-521
|
| 16508011 |
Paliwal S et al.:
Targeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis
Mol. Cell. Biol.
2006
26: 2360-2372
|
| 14567915 |
Zhang Q et al.:
Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP
Cell
2003
115: 177-186
|
| 19181930 |
Wang J et al.:
The transcription repressor, ZEB1, cooperates with CtBP2 and HDAC1 to suppress IL-2 gene activation in T cells
Int. Immunol.
2009
21: 227-235
|
| 10567582 |
Furusawa T et al.:
Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1
Mol. Cell. Biol.
1999
19: 8581-8590
|
| 19825414 |
Tarleton HP et al.:
Delayed differentiation in embryonic stem cells and mesodermal progenitors in the absence of CtBP2
Mech. Dev.
2010
127: 107-119
|
| 16356938 |
Zhao LJ et al.:
Acetylation by p300 regulates nuclear localization and function of the transcriptional corepressor CtBP2
J. Biol. Chem.
2006
281: 4183-4189
|
| 11504872 |
Murakami A et al.:
SOX6 binds CtBP2 to repress transcription from the Fgf-3 promoter
Nucleic Acids Res.
2001
29: 3347-3355
|
| 10359772 |
Postigo AA et al.:
ZEB represses transcription through interaction with the corepressor CtBP
Proc. Natl. Acad. Sci. U.S.A.
1999
12: 6683-6688
|
| 16740659 |
Zhang Q et al.:
Redox sensor CtBP mediates hypoxia-induced tumor cell migration
Proc. Natl. Acad. Sci. U.S.A.
2006
103: 9029-9033
|
| 19700740 |
Schmitz F et al.:
The making of synaptic ribbons: how they are built and what they do
Neuroscientist
2009
15: 611-624
|
| 18850205 |
Vasku JA et al.:
Association of leptin genetic polymorphism -2548 G/A with gestational diabetes mellitus
Genes Nutr
2006
1: 117-123
|
| 27125397 |
Gong LL et al.:
Relationship between hypothyroidism and the incidence of gestational diabetes: A meta-analysis
Taiwan J Obstet Gynecol
2016
55: 171-175
|
| 26550492 |
Santa LM et al.:
AngiomiRs: Potential Biomarkers of Pregnancys Vascular Pathologies
J Pregnancy
2015
2015
|
| 27246871 |
Gao J et al.:
Association between serum bile acid profiles and gestational diabetes mellitus: A targeted metabolomics study
Clin. Chim. Acta
2016
459: 63-72
|
| 28360945 |
Haertle L et al.:
Epigenetic signatures of gestational diabetes mellitus on cord blood methylation
Clin Epigenetics
2017
9: 28
|
| 28537583 |
Brei C et al.:
Impact of the n-6:n-3 long-chain PUFA ratio during pregnancy and lactation on offspring neurodevelopment: 5-year follow-up of a randomized controlled trial
|
| 24068295 |
Beltcheva O et al.:
The rs266729 single-nucleotide polymorphism in the adiponectin gene shows association with gestational diabetes
Arch. Gynecol. Obstet.
2014
289: 743-748
|
| 26975349 |
Hu S et al.:
Serum level and polymorphisms of retinol-binding protein-4 and risk for gestational diabetes mellitus: a meta-analysis
BMC Pregnancy Childbirth
2016
16: 52
|
| 24082721 |
Amiri FN et al.:
Comparison of the serum iron, ferritin levels and total iron-binding capacity between pregnant women with and without gestational diabetes
J Nat Sci Biol Med
2013
4: 302-305
|
| 27511926 |
Bowers KA et al.:
Plasma Concentrations of Ferritin in Early Pregnancy Are Associated with Risk of Gestational Diabetes Mellitus in Women in the Danish National Birth Cohort
J. Nutr.
2016
146: 1756-1761
|
| 27867874 |
Bhograj A et al.:
Serum adiponectin levels in gestational diabetes mellitus
Indian J Endocrinol Metab
2016
20: 752-755
|
| 26677023 |
Liu T et al.:
Comprehensive analysis of serum metabolites in gestational diabetes mellitus by UPLC/Q-TOF-MS
Anal Bioanal Chem
2016
408: 1125-1135
|
| 24947484 |
Hinkle SN et al.:
First trimester coffee and tea intake and risk of gestational diabetes mellitus: a study within a national birth cohort
BJOG
2015
122: 420-428
|
| 25193282 |
Huynh J et al.:
A systematic review of metabolite profiling in gestational diabetes mellitus
Diabetologia
2014
57: 2453-2464
|
| 24526261 |
Lacroix M et al.:
Lower vitamin D levels at first trimester are associated with higher risk of developing gestational diabetes mellitus
Acta Diabetol
2014
51: 609-616
|
| 28238935 |
Law KP et al.:
Tryptophan and purine metabolites are consistently upregulated in the urinary metabolome of patients diagnosed with gestational diabetes mellitus throughout pregnancy: A longitudinal metabolomics study of Chinese pregnant women part 2
Clin. Chim. Acta
2017
468: 126-139
|
| 23921142 |
Pagan A et al.:
Materno-fetal transfer of docosahexaenoic acid is impaired by gestational diabetes mellitus
Am. J. Physiol. Endocrinol. Metab.
2013
305: E826-E833
|
| 26101084 |
Shapiro GD et al.:
Exposure to phthalates, bisphenol A and metals in pregnancy and the association with impaired glucose tolerance and gestational diabetes mellitus: The MIREC study
Environ Int
2015
83: 63-71
|
| 27825389 |
Farzan SF et al.:
Maternal arsenic exposure and gestational diabetes and glucose intolerance in the New Hampshire birth cohort study
Environ Health
2016
15: 106
|
| 26825733 |
Lu M et al.:
Association between vitamin D status and the risk of gestational diabetes mellitus: a meta-analysis
Arch. Gynecol. Obstet.
2016
293: 959-966
|
| 21887347 |
Zhao C et al.:
Early second-trimester serum miRNA profiling predicts gestational diabetes mellitus
PLoS ONE
2011
6
|
| 20960114 |
Akturk M et al.:
Asymmetric dimethylarginine concentrations are elevated in women with gestational diabetes
Endocrine
2010
38: 134-141
|
| 25748329 |
Bentley-Lewis R et al.:
Metabolomic profiling in the prediction of gestational diabetes mellitus
Diabetologia
2015
58: 1329-1332
|
| 16770586 |
Guven MA et al.:
Elevated second trimester serum homocysteine levels in women with gestational diabetes mellitus
Arch. Gynecol. Obstet.
2006
274: 333-337
|
| 27703025 |
Lu L et al.:
An Unbiased Lipidomics Approach Identifies Early Second Trimester Lipids Predictive of Maternal Glycemic Traits and Gestational Diabetes Mellitus
Diabetes Care
2016
39: 2232-2239
|
| 12800097 |
Seghieri G et al.:
Serum homocysteine levels are increased in women with gestational diabetes mellitus
Metab. Clin. Exp.
2003
52: 720-723
|
| 15144335 |
Tarim E et al.:
Elevated plasma homocysteine levels in gestational diabetes mellitus
Acta Obstet Gynecol Scand
2004
83: 543-547
|
| 27468700 |
Wu L et al.:
Genetic variants associated with gestational diabetes mellitus: a meta-analysis and subgroup analysis
Sci Rep
2016
6: 30539
|
| 22096510 |
Wang Y et al.:
Association of six single nucleotide polymorphisms with gestational diabetes mellitus in a Chinese population
PLoS ONE
2011
6
|
| 23456907 |
Stuebe AM et al.:
Maternal genotype and gestational diabetes
Am J Perinatol
2014
31: 69-76
|
| 27636996 |
Shi A et al.:
Genetic variants in vitamin D signaling pathways and risk of gestational diabetes mellitus
Oncotarget
2016
7
|
| 23029294 |
Mao H et al.:
Meta-analysis of the relationship between common type 2 diabetes risk gene variants with gestational diabetes mellitus
PLoS ONE
2012
7
|
| 23862583 |
Kim JY et al.:
Putative association between UBE2E2 polymorphisms and the risk of gestational diabetes mellitus
Gynecol. Endocrinol.
2013
29: 904-908
|
| 23790250 |
Araujo JR et al.:
Gestational diabetes mellitus decreases placental uptake of long-chain polyunsaturated fatty acids: involvement of long-chain acyl-CoA synthetase
J. Nutr. Biochem.
2013
24: 1741-1750
|
| 27988319 |
Law KP et al.:
Unsaturated plasma phospholipids are consistently lower in the patients diagnosed with gestational diabetes mellitus throughout pregnancy: A longitudinal metabolomics study of Chinese pregnant women part 1
Clin. Chim. Acta
2017
465: 53-71
|
| 27667090 |
Hou W et al.:
Elevated First-Trimester Total Bile Acid is Associated with the Risk of Subsequent Gestational Diabetes
Sci Rep
2016
6: 34070
|
| 18573524 |
Heazell AE et al.:
Analysis of the metabolic footprint and tissue metabolome of placental villous explants cultured at different oxygen tensions reveals novel redox biomarkers
Placenta
2008
29: 691-698
|
| 25202675 |
Gloria-Bottini F et al.:
A study of adenylate kinase locus 1 (ak 1 ) genetic polymorphism in diabetic pregnancy
J Reprod Infertil
2014
15: 161-164
|
| 22808198 |
Salomon C et al.:
Gestational diabetes reduces adenosine transport in human placental microvascular endothelium, an effect reversed by insulin
PLoS ONE
2012
7
|
| 24448600 |
Monroy VS et al.:
Thr130Ile polymorphism of HNF4A gene is associated with gestational diabetes mellitus in Mexican population
J Investig Med
2014
62: 632-634
|
| 34358830 |
author information missing
article information missing
|
| 11326298 |
Meyer J et al.:
A missense mutation in a novel gene encoding a putative cation channel is associated with catatonic schizophrenia in a large pedigree
Mol. Psychiatry
2001
6: 302-306
|
| 16731849 |
Huang C et al.:
Diabetic nephropathy is associated with gene expression levels of oxidative phosphorylation and related pathways
Diabetes
2006
55: 1826-1831
|
| 30317577 |
Yu FN et al.:
Effects of microRNA-370 on mesangial cell proliferation and extracellular matrix accumulation by binding to canopy 1 in a rat model of diabetic nephropathy
J. Cell. Physiol.
2019
234: 6898-6907
|
| 31942046 |
Tang SCW et al.:
Innate immunity in diabetic kidney disease
Nat Rev Nephrol
2020
16: 206-222
|
| 31011203 |
Niewczas MA et al. et al.:
A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes
Nat Med
2019
25: 805-813
|
| 28431867 |
Ung C et al. et al.:
Whole exome sequencing identification of novel candidate genes in patients with proliferative diabetic retinopathy
Vision Res
2017
139: 168-176
|
| 30989829 |
MacIsaac RJ et al.:
Changes in soluble tumor necrosis factor receptor type 1 levels and early renal function decline in patients with diabetes
J Diabetes Investig
2019
10: 1537-1542
|
| 27482889 |
author information missing
Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury
J Clin Invest
2016
126: 3336-3350
|
| 26063200 |
Liu X et al.:
Blockade of vascular endothelial growth factor-A/receptor 2 exhibits a protective effect on angiotensin-II stimulated podocytes
Mol Med Rep
2015
12: 4340-4345
|
| 7924884 |
Tada H et al.:
A high concentration of glucose alters the production of tPA, uPA and PAI-1 antigens from human mesangial cells
Diabetes Res Clin Pract
1994
24: 33-39
|
| 28495930 |
Dhanesha N et al.:
ADAMTS13 Retards Progression of Diabetic Nephropathy by Inhibiting Intrarenal Thrombosis in Mice
Arterioscler Thromb Vasc Biol
2017
37: 1332-1338
|
| 26119175 |
Hu C et al.:
Insights into the Mechanisms Involved in the Expression and Regulation of Extracellular Matrix Proteins in Diabetic Nephropathy
Curr Med Chem
2015
22: 2858-2870
|
| 26629006 |
Wang X et al.:
Follistatin-like 3 suppresses cell proliferation and fibronectin expression via p38MAPK pathway in rat mesangial cells cultured under high glucose
Int J Clin Exp Med
2015
8
|
| 10703682 |
Lenz O et al.:
Matrix metalloproteinases in renal development and disease
J Am Soc Nephrol
2000
11: 574-581
|
| 11976203 |
Hipkiss AR et al.:
Reaction of carnosine with aged proteins: another protective process?
Ann N Y Acad Sci
2002
959: 285-294
|
| 15569303 |
Fukami K et al. et al.:
AGEs activate mesangial TGF-beta-Smad signaling via an angiotensin II type I receptor interaction
Kidney Int
2004
66: 2137-2147
|
| 30862474 |
Yang H et al. et al.:
Tim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-kappaB/TNF-alpha pathway
Mol Metab
2019
23: 24-36
|
| 32953797 |
Zhang Y et al.:
Identification of hub genes in diabetic kidney disease via multiple-microarray analysis
Ann Transl Med
2020
8: 997
|
| 25957229 |
Fang F et al.:
Deletion of the gene for adiponectin accelerates diabetic nephropathy in the Ins2 (+/C96Y) mouse
Diabetologia
2015
58: 1668-1678
|
| 30515388 |
Haku S et al. et al.:
Early Enhanced Leucine-Rich alpha-2-Glycoprotein-1 Expression in Glomerular Endothelial Cells of Type 2 Diabetic Nephropathy Model Mice
Biomed Res Int
2018
2018
|
| 25280384 |
Nazir N et al.:
Meta-analysis of diabetic nephropathy associated genetic variants in inflammation and angiogenesis involved in different biochemical pathways
BMC Med Genet
2014
15: 103
|
| 20307901 |
Taniguchi S et al.:
Association between reduced ADAMTS13 and diabetic nephropathy
Thromb Res
2010
125: e310-e316
|
| 8603776 |
Sharma K et al.:
Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice
Diabetes
1996
45: 522-530
|
| 26719364 |
Chang AS et al.:
Transforming growth factor-beta1 and diabetic nephropathy
Am J Physiol Renal Physiol
2016
310: F689-F696
|
| 15496151 |
Wassef L et al.:
Epidermal growth factor receptor inhibition attenuates early kidney enlargement in experimental diabetes
Kidney Int
2004
66: 1805-1814
|
| 16105029 |
Saad S et al.:
High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule
Kidney Int
2005
68: 985-997
|
| 26116588 |
Perlman AS et al.:
Serum Inflammatory and Immune Mediators Are Elevated in Early Stage Diabetic Nephropathy
Ann Clin Lab Sci
2015
45: 256-263
|
| 20946020 |
Fan JP et al.:
Ameliorating effects of L-carnitine on diabetic podocyte injury
J Med Food
2010
13: 1324-1330
|
| 24371263 |
Herman-Edelstein M et al.:
Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy
J Lipid Res
2014
55: 561-572
|
| 18392786 |
Davis LK et al.:
Angiotensin II- and glucose-stimulated extracellular matrix production: mediation by the insulin-like growth factor (IGF) axis in a murine mesangial cell line
Endocrine
2008
33: 32-39
|
| 29660205 |
Han Q et al.:
Thyroid hormones and diabetic nephropathy: An essential relationship to recognize
Nephrology (Carlton)
2019
24: 160-169
|
| 30631416 |
Zhao W et al.:
Thyroid Function in Patients with Type 2 Diabetes Mellitus and Diabetic Nephropathy: A Single Center Study
J Thyroid Res
2018
2018
|
| 28363692 |
Feigerlova E et al.:
IL-6 signaling in diabetic nephropathy: From pathophysiology to therapeutic perspectives
Cytokine Growth Factor Rev
2017
37: 57-65
|
| 19323980 |
Hara T et al.:
Endothelial cell-selective adhesion molecule regulates albuminuria in diabetic nephropathy
Microvasc Res
2009
77: 348-355
|
| 32065170 |
Muthusamy A et al.:
Demonstrating a Linear Relationship Between Vascular Endothelial Growth Factor and Luteinizing Hormone in Kidney Cortex Extracts
|
| 21067510 |
Kumar PA et al.:
The glomerular podocyte as a target of growth hormone action: implications for the pathogenesis of diabetic nephropathy
Curr Diabetes Rev
2011
7: 50-55
|
| 28760771 |
Tesch GH et al.:
Diabetic nephropathy - is this an immune disorder?
Clin Sci (Lond)
2017
131: 2183-2199
|
| 27519211 |
Donegan D et al.:
PAPP-A in normal human mesangial cells: effect of inflammation and factors related to diabetic nephropathy
J Endocrinol
2016
231: 71-80
|
| 23881937 |
Mader JR et al.:
Mice deficient in PAPP-A show resistance to the development of diabetic nephropathy
J Endocrinol
2013
219: 51-58
|
| 28933050 |
Garibotto G et al.:
Toll-like receptor-4 signaling mediates inflammation and tissue injury in diabetic nephropathy
J Nephrol
2017
30: 719-727
|
| 33013450 |
Lin PH et al.:
Dyslipidemia in Kidney Disorders: Perspectives on Mitochondria Homeostasis and Therapeutic Opportunities
Front Physiol
2020
11: 1050
|
| 30362661 |
Xie P et al.:
Renal dysfunction aggravated impaired cutaneous wound healing in diabetic mice
Wound Repair Regen
2019
27: 49-58
|
| 20687922 |
Maeshima Y et al.:
Angiogenesis and chronic kidney disease
Fibrogenesis Tissue Repair
2010
3: 13
|
| 31754839 |
Ducasa GM et al.:
Crosstalk Between Lipids and Mitochondria in Diabetic Kidney Disease
Curr Diab Rep
2019
19: 144
|
| 32226789 |
Jang HS et al.:
Defective Mitochondrial Fatty Acid Oxidation and Lipotoxicity in Kidney Diseases
Front Med (Lausanne)
2020
7: 65
|
| 23207723 |
Brosius FC 3rd et al.:
New targets for treatment of diabetic nephropathy: what we have learned from animal models
Curr Opin Nephrol Hypertens
2013
22: 17-25
|
| 10792615 |
Thuraisingham RC et al.:
Increased nitrotyrosine staining in kidneys from patients with diabetic nephropathy
Kidney Int
2000
57: 1968-1972
|
| 29196928 |
Chen Y et al.:
The effect of L-thyroxine substitution on oxidative stress in early-stage diabetic nephropathy patients with subclinical hypothyroidism: a randomized double-blind and placebo-controlled study
Int Urol Nephrol
2018
50: 97-103
|
| 31352157 |
Brittain AL et al.:
A review of renal GH/IGF1 family gene expression in chronic kidney diseases
Growth Horm IGF Res
2019
48-49: 1-4
|
| 31116066 |
Murphy-Ullrich JE et al.:
Thrombospondin 1 and Its Diverse Roles as a Regulator of Extracellular Matrix in Fibrotic Disease
J Histochem Cytochem
2019
67: 683-699
|
| 21307121 |
Lin Y et al.:
Thyroid hormone ameliorates diabetic nephropathy in a mouse model of type II diabetes
J Endocrinol
2011
209: 185-191
|
| 25003613 |
Kato M et al.:
Diabetic nephropathy--emerging epigenetic mechanisms
Nat Rev Nephrol
2014
10: 517-530
|
| 28178341 |
Kim SS et al.:
Enhanced expression of two discrete isoforms of matrix metalloproteinase-2 in experimental and human diabetic nephropathy
PLoS One
2017
12
|
| 25349246 |
Ding Y et al.:
Autophagy in diabetic nephropathy
J Endocrinol
2015
224: R15-R30
|
| 30831151 |
Wen H et al. et al.:
Grem2 mediates podocyte apoptosis in high glucose milieu
Biochimie
2019
160: 113-121
|
| 28893420 |
Galvan DL et al.:
The hallmarks of mitochondrial dysfunction in chronic kidney disease
Kidney Int
2017
92: 1051-1057
|
| 32982792 |
Zhang A et al.:
Role of VEGF-A and LRG1 in Abnormal Angiogenesis Associated With Diabetic Nephropathy
Front Physiol
2020
11: 1064
|
| 24861084 |
Fornoni A et al.:
Lipid biology of the podocyte--new perspectives offer new opportunities
Nat Rev Nephrol
2014
10: 379-388
|
| 26261560 |
Ji Z et al.:
APPL1 acts as a protective factor against podocytes injury in high glucose environment
Int J Clin Exp Pathol
2015
8: 6764-6771
|
| 26767865 |
Kim HW et al.:
Angiotensin III increases monocyte chemoattractant protein-1 expression in cultured human proximal tubular epithelial cells
Korean J Intern Med
2016
31: 116-124
|
| 19065132 |
Velez JC et al.:
The importance of the intrarenal renin-angiotensin system
Nat Clin Pract Nephrol
2009
5: 89-100
|
| 11961003 |
Lorenzo O et al.:
Angiotensin III activates nuclear transcription factor-kappaB in cultured mesangial cells mainly via AT(2) receptors: studies with AT(1) receptor-knockout mice
J Am Soc Nephrol
2002
13: 1162-1171
|
| 12819233 |
Huang XR et al.:
Chymase is upregulated in diabetic nephropathy: implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease
J Am Soc Nephrol
2003
14: 1738-1747
|
| 19934006 |
Oudit GY et al. et al.:
Human recombinant ACE2 reduces the progression of diabetic nephropathy
Diabetes
2010
59: 529-538
|
| 33658594 |
Valdes A et al.:
Comprehensive metabolomic study of the response of HK-2 cells to hyperglycemic hypoxic diabetic-like milieu
Sci Rep
2021
11: 5058
|
| 20826743 |
Pacal L et al.:
Role of thiamine status and genetic variability in transketolase and other pentose phosphate cycle enzymes in the progression of diabetic nephropathy
Nephrol Dial Transplant
2011
26: 1229-1236
|
| 15956780 |
Xu Y et al.:
Diabetes causes inhibition of glucose-6-phosphate dehydrogenase via activation of PKA, which contributes to oxidative stress in rat kidney cortex
Am J Physiol Renal Physiol
2005
289
|
| 22431005 |
Stanton RC et al.:
Glucose-6-phosphate dehydrogenase, NADPH, and cell survival
IUBMB Life
2012
64: 362-369
|
| 31285429 |
Lee SE et al. et al.:
Mesenchymal stem cells prevent the progression of diabetic nephropathy by improving mitochondrial function in tubular epithelial cells
Exp Mol Med
2019
51: 1-14
|
| 25761429 |
Sun H et al.:
Pentraxin-3 Attenuates Renal Damage in Diabetic Nephropathy by Promoting M2 Macrophage Differentiation
Inflammation
2015
38: 1739-1747
|
| 29061302 |
Zhao Y et al.:
Mitophagy regulates macrophage phenotype in diabetic nephropathy rats
Biochem Biophys Res Commun
2017
494: 42-50
|
| 24720258 |
Higgins GC et al.:
Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?
Br J Pharmacol
2014
171: 1917-1942
|
| 21785041 |
author information missing
article information missing
|
| 25957525 |
author information missing
article information missing
|
| 34616096 |
author information missing
article information missing
|
| 29520581 |
author information missing
article information missing
|
| 33375198 |
author information missing
article information missing
|
| 21300820 |
author information missing
article information missing
|
| 32733282 |
author information missing
article information missing
|
| 27173460 |
author information missing
article information missing
|
| 26200946 |
author information missing
article information missing
|
| 26301223 |
author information missing
article information missing
|
| 29142974 |
author information missing
article information missing
|
| 30173364 |
author information missing
article information missing
|
| 33907247 |
author information missing
article information missing
|
| 34346315 |
author information missing
article information missing
|
| 17603080 |
author information missing
article information missing
|
| 28201997 |
author information missing
article information missing
|
| 26772879 |
author information missing
article information missing
|
| 34663875 |
author information missing
article information missing
|
| 25034792 |
author information missing
article information missing
|
| 18587495 |
Kane R et al.:
Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis
Mol. Vis.
2008
14: 1138-1148
|
| 24894401 |
Kowluru RA et al.:
Sirt1, a negative regulator of matrix metalloproteinase-9 in diabetic retinopathy
Invest. Ophthalmol. Vis. Sci.
2014
55: 5653-5660
|
| 27261371 |
Abu El-Asrar AM et al.:
Upregulation of Thrombin/Matrix Metalloproteinase-1/Protease-Activated Receptor-1 Chain in Proliferative Diabetic Retinopathy
Curr Eye Res
2016
41: 1590-1600
|
| 22363694 |
Zhang Y et al.:
High glucose decreases expression and activity of p-glycoprotein in cultured human retinal pigment epithelium possibly through iNOS induction
PLoS One
2012
7
|
| 2642484 |
Danser AH et al.:
Renin, prorenin, and immunoreactive renin in vitreous fluid from eyes with and without diabetic retinopathy
J Clin Endocrinol Metab
1989
68: 160-167
|
| 3887168 |
author information missing
Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications
N Engl J Med
1985
312: 1412-1417
|
| 29761600 |
Duan Y et al. et al.:
Loss of Angiotensin-Converting Enzyme 2 Exacerbates Diabetic Retinopathy by Promoting Bone Marrow Dysfunction
Stem Cells
2018
36: 1430-1440
|
| 27184051 |
author information missing
article information missing
|
| 30096827 |
author information missing
article information missing
|
| 20881945 |
Carpenter LL et al.:
Association between plasma IL-6 response to acute stress and early-life adversity in healthy adults.
Neuropsychopharmacology
2010
35: 2617-2623
|
| 22137507 |
van Zuiden M et al.:
Glucocorticoid receptor pathway components predict posttraumatic stress disorder symptom development: a prospective study.
Biol. Psychiatry
2012
71: 309-316
|
| 21925847 |
Koresh O et al.:
The long-term abnormalities in circadian expression of Period 1 and Period 2 genes in response to stress is normalized by agomelatine administered immediately after exposure.
Eur Neuropsychopharmacol
2012
22: 205-221
|
| 20439746 |
Uddin M et al.:
Epigenetic and immune function profiles associated with posttraumatic stress disorder
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 9470-9475
|
| 22332656 |
Rusiecki JA et al.:
DNA methylation in repetitive elements and post-traumatic stress disorder: a case-control study of US military service members
Epigenomics
2012
4: 29-40
|
| 21714072 |
Smith AK et al.:
Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2011
156B: 700-708
|
| 21508515 |
Uddin M et al.:
Gene expression and methylation signatures of MAN2C1 are associated with PTSD
Dis. Markers
2011
30: 111-121
|
| 21350482 |
Ressler KJ et al.:
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor
Nature
2011
470: 492-497
|
| 20439746 |
Uddin M et al.:
Epigenetic and immune function profiles associated with posttraumatic stress disorder
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 9470-9475
|
| 19702553 |
Merenlender-Wagner A et al.:
The beta-endorphin role in stress-related psychiatric disorders
Curr Drug Targets
2009
10: 1096-1108
|
| 22586106 |
de Quervain DJ et al.:
PKCalpha is genetically linked to memory capacity in healthy subjects and to risk for posttraumatic stress disorder in genocide survivors
Proc. Natl. Acad. Sci. U.S.A.
2012
109: 8746-8751
|
| 23630272 |
Mehta D et al.:
Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder
Proc. Natl. Acad. Sci. U.S.A.
2013
110: 8302-8307
|
| 20439828 |
Sacher J et al.:
Elevated brain monoamine oxidase A binding in the early postpartum period.
Arch. Gen. Psychiatry
2010
67: 468-474
|
| 19850056 |
Navarre BM et al.:
Anhedonia in postpartum rats.
Physiol. Behav.
2010
99: 59-66
|
| 19185297 |
Zou Y et al.:
Hormonal changes and somatopsychologic manifestations in the first trimester of pregnancy and post partum.
Int J Gynaecol Obstet
2009
105: 46-49
|
| 21168281 |
Labad J et al.:
Increased morning adrenocorticotrophin hormone (ACTH) levels in women with postpartum thoughts of harming the infant.
Psychoneuroendocrinology
2011
36: 924-928
|
| 20708275 |
Okun ML et al.:
Changes in sleep quality, but not hormones predict time to postpartum depression recurrence.
J Affect Disord
2011
130: 378-384
|
| 18471802 |
Suda S et al.:
A postpartum model in rat: behavioral and gene expression changes induced by ovarian steroid deprivation.
Biol. Psychiatry
2008
64: 311-319
|
| 19581911 |
Segman RH et al.:
Blood mononuclear cell gene expression signature of postpartum depression
Mol Psychiatry
2010
15: 93-100
|
| 10559188 |
Wang S et al.:
A Sp1 binding site of the tumor necrosis factor alpha promoter functions as a nitric oxide response element.
J. Biol. Chem.
1999
274
|
| 18708264 |
Boufidou F et al.:
CSF and plasma cytokines at delivery and postpartum mood disturbances.
J Affect Disord
2009
115: 287-292
|
| 9712915 |
Redell JB et al.:
Multiple promoter elements interact to control the transcription of the potassium channel gene, KCNJ2.
J. Biol. Chem.
1998
273
|
| 11294852 |
Nicolas M et al.:
Cloning and characterization of the 5-flanking region of the human transcription factor Sp1 gene.
J. Biol. Chem.
2001
276
|
| 11390427 |
Denson LA et al.:
TNF-alpha downregulates murine hepatic growth hormone receptor expression by inhibiting Sp1 and Sp3 binding.
J. Clin. Invest.
2001
107: 1451-1458
|
| 10684975 |
Park IK et al.:
Sp1 mediates constitutive and transforming growth factor beta-inducible expression of urokinase type plasminogen activator receptor gene in human monocyte-like U937 cells.
Biochim. Biophys. Acta
2000
1490: 302-310
|
| 15056867 |
Yamakami M et al.:
Tom1 (target of Myb 1) is a novel negative regulator of interleukin-1- and tumor necrosis factor-induced signaling pathways.
Biol. Pharm. Bull.
2004
27: 564-566
|
| 20468050 |
Baker BJ et al.:
IL-27 inhibits OSM-mediated TNF-alpha and iNOS gene expression in microglia
Glia
2010
58: 1082-1093
|
| 18802049 |
Vila-del Sol V et al.:
IFN-gamma-induced TNF-alpha expression is regulated by interferon regulatory factors 1 and 8 in mouse macrophages.
J. Immunol.
2008
181: 4461-4470
|
| 18345002 |
Yarilina A et al.:
TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes.
Nat. Immunol.
2008
9: 378-387
|
| 11698396 |
Zhou G et al.:
Protein phosphatase 4 is involved in tumor necrosis factor-alpha-induced activation of c-Jun N-terminal kinase.
J. Biol. Chem.
2002
277: 6391-6398
|
| 2501120 |
Georg B et al.:
Tumor necrosis factor-alpha regulates mRNA for urokinase-type plasminogen activator and type-1 plasminogen activator inhibitor in human neoplastic cell lines.
Mol. Cell. Endocrinol.
1989
61: 87-96
|
| 9822259 |
Guo H et al.:
Regulation of beta-chemokine mRNA expression in adult rat astrocytes by lipopolysaccharide, proinflammatory and immunoregulatory cytokines
Scand. J. Immunol.
1998
48: 502-508
|
| 20004646 |
Lee HL et al.:
Tumor necrosis factor-alpha increases alkaline phosphatase expression in vascular smooth muscle cells via MSX2 induction.
Biochem. Biophys. Res. Commun.
2010
391: 1087-1092
|
| 11694349 |
Book McAlexander M et al.:
Sp1 is required for prolactin activation of the interferon regulatory factor-1 gene.
Mol. Cell. Endocrinol.
2001
184: 135-141
|
| 12390531 |
Kasza A et al.:
Mechanism of plasminogen activator inhibitor-1 regulation by oncostatin M and interleukin-1 in human astrocytes.
J. Neurochem.
2002
83: 696-703
|
| 17543959 |
Moses-Kolko EL et al.:
Serotonin 1A receptor reductions in postpartum depression: a positron emission tomography study.
Fertil. Steril.
2008
89: 685-692
|
| 21248071 |
Crone J et al.:
Zyxin is a critical regulator of the apoptotic HIPK2-p53 signaling axis.
Cancer Res.
2011
71: 2350-2359
|
| 8016121 |
Iwabuchi K et al.:
Two cellular proteins that bind to wild-type but not mutant p53.
Proc. Natl. Acad. Sci. U.S.A.
1994
91: 6098-6102
|
| 12603855 |
Kanda N et al.:
17beta-estradiol inhibits the production of RANTES in human keratinocytes
J. Invest. Dermatol.
2003
120: 420-427
|
| 11953428 |
Amir RE et al.:
The NEDD8 pathway is essential for SCF(beta -TrCP)-mediated ubiquitination and processing of the NF-kappa B precursor p105
J. Biol. Chem.
2002
277
|
| 28546751 |
Lin L et al.:
Novel urinary metabolite signature for diagnosing postpartum depression
Neuropsychiatr Dis Treat
2017
13: 1263-1270
|
| 19625011 |
Doornbos B et al.:
The development of peripartum depressive symptoms is associated with gene polymorphisms of MAOA, 5-HTT and COMT
Prog. Neuropsychopharmacol. Biol. Psychiatry
2009
33: 1250-1254
|
| 20421498 |
Farci P et al.:
B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus-associated acute liver failure.
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 8766-8771
|
| 28436541 |
Caetano LA et al.:
PDX1 -MODY and dorsal pancreatic agenesis: New phenotype of a rare disease
Clin Genet
2018
93: 382-386
|
| 31578821 |
Abreu GM et al.:
The first case of NEUROD1-MODY reported in Latin America
Mol Genet Genomic Med
2019
7: e989
|
| 28664602 |
Horikawa Y et al.:
NEUROD1-deficient diabetes (MODY6): Identification of the first cases in Japanese and the clinical features
Pediatr Diabetes
2018
19: 236-242
|
| 26773576 |
Szopa M et al.:
A family with the Arg103Pro mutation in the NEUROD1 gene detected by next-generation sequencing - Clinical characteristics of mutation carriers
Eur J Med Genet
2016
59: 75-79
|
| 31124255 |
Ushijima K et al.:
KLF11 variant in a family clinically diagnosed with early childhood-onset type 1B diabetes
Pediatr Diabetes
2019
20: 712-719
|
| 33072637 |
Sarmadi A et al.:
Molecular Genetic Study in a Cohort of Iranian Families Suspected to Maturity-Onset Diabetes of the Young, Reveals a Recurrent Mutation and a High-Risk Variant in the CEL Gene
Adv Biomed Res
2020
9: 25
|
| 29552330 |
Lombardo D et al.:
Pancreatic adenocarcinoma, chronic pancreatitis, and MODY-8 diabetes: is bile salt-dependent lipase (or carboxyl ester lipase) at the crossroads of pancreatic pathologies?
Oncotarget
2017
9
|
| 32801813 |
Abreu GM et al.:
Identification of the First PAX4-MODY Family Reported in Brazil
Diabetes Metab Syndr Obes
2020
13: 2623-2631
|
| 25951767 |
Sujjitjoon J et al.:
Aberrant mRNA splicing of paired box 4 (PAX4) IVS7-1G>A mutation causing maturity-onset diabetes of the young, type 9
Acta Diabetol
2016
53: 205-216
|
| 25721872 |
Dusatkova L et al.:
Frameshift mutations in the insulin gene leading to prolonged molecule of insulin in two families with Maturity-Onset Diabetes of the Young
Eur J Med Genet
2015
58: 230-234
|
| 33194056 |
Lei SQ et al.:
MODY10 caused by c.309-314del CCAGCT insGCGC mutation of the insulin gene: a case report
Am J Transl Res
2020
12: 6599-6607
|
| 32405973 |
Zhang J et al. et al.:
Identification of Ala2Thr mutation in insulin gene from a Chinese MODY10 family
Mol Cell Biochem
2020
470: 77-86
|
| 28992123 |
Yan J et al.:
Whole-exome sequencing identifies a novel INS mutation causative of maturity-onset diabetes of the young 10
J Mol Cell Biol
2017
9: 376-383
|
| 20007936 |
Meur G et al. et al.:
Insulin gene mutations resulting in early-onset diabetes: marked differences in clinical presentation, metabolic status, and pathogenic effect through endoplasmic reticulum retention
Diabetes
2010
59: 653-661
|
| 19647945 |
Kluge M et al.:
Ghrelin increases slow wave sleep and stage 2 sleep and decreases stage 1 sleep and REM sleep in elderly men but does not affect sleep in elderly women
Psychoneuroendocrinology
2010
35: 297-304
|
| 22259063 |
Kluge M et al.:
Ghrelin suppresses secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in women
J. Clin. Endocrinol. Metab.
2012
97: E448-E451
|
| 19622385 |
Klein DC et al.:
Pineal function: impact of microarray analysis
Mol. Cell. Endocrinol.
2010
314: 170-183
|
| 21653847 |
Burkeen JF et al.:
Mitochondrial calcium signaling mediates rhythmic extracellular ATP accumulation in suprachiasmatic nucleus astrocytes
J. Neurosci.
2011
31: 8432-8440
|
| 23440187 |
Moller-Levet CS et al.:
Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome
Proc Natl Acad Sci U S A
2013
110
|
| 22396548 |
Hamdan AM et al.:
Intestinal expression of mouse Abcg2/breast cancer resistance protein (BCRP) gene is under control of circadian clock-activating transcription factor-4 pathway
J. Biol. Chem.
2012
287
|
| 20203314 |
Durgan DJ et al.:
The cardiomyocyte circadian clock: emerging roles in health and disease
Circ. Res.
2010
106: 647-658
|
| 19776257 |
Gamble KL et al.:
Ryanodine receptors are regulated by the circadian clock and implicated in gating photic entrainment
J. Neurosci.
2009
29
|
| 23364267 |
Schroder EA et al.:
The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility
Am. J. Physiol.
2013
304: C954-C965
|
| 23288979 |
Deboer T et al.:
Reduced sleep and low adenosinergic sensitivity in cacna1a R192Q mutant mice
Sleep
2013
36: 127-136
|
| 12213830 |
Xiao B et al.:
Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors)
J. Biol. Chem.
2002
277
|
| 15305881 |
Kuhlman SJ et al.:
Rhythmic regulation of membrane potential and potassium current persists in SCN neurons in the absence of environmental input
Eur. J. Neurosci.
2004
20: 1113-1117
|
| 22738311 |
Hida A et al.:
Pathophysiology and pathogenesis of circadian rhythm sleep disorders
J Physiol Anthropol
2012
31: 7
|
| 22629359 |
Barclay JL et al.:
Circadian desynchrony promotes metabolic disruption in a mouse model of shiftwork
PLoS ONE
2012
7
|
| 23637193 |
Bhattacharya A et al.:
Potentiation of inhibitory synaptic transmission by extracellular ATP in rat suprachiasmatic nuclei
J. Neurosci.
2013
33: 8035-8044
|
| 8795640 |
van den Pol AN et al.:
Neuropeptide Y-mediated long-term depression of excitatory activity in suprachiasmatic nucleus neurons
J. Neurosci.
1996
16: 5883-5895
|
| 23420534 |
Tong M et al.:
Circadian expressions of cardiac ion channel genes in mouse might be associated with the central clock in the SCN but not the peripheral clock in the heart
Biol Rhythm Res
2013
44: 519-530
|
| 23712055 |
Lee W et al.:
Clinical, laboratory and electrophysiological features of Morvans Fibrillary Chorea
J Clin Neurosci
2013
20: 1246-1249
|
| 16278841 |
Savader SJ et al.:
Hemobilia after percutaneous transhepatic biliary drainage: treatment with transcatheter embolotherapy
J Vasc Interv Radiol
1992
3: 345-352
|
| 18976777 |
Qiu X et al.:
Patient with obstructive sleep apnea-hypopnea syndrome and SCN5A mutation (R1193Q polymorphism) associated with Brugada type 2 electrocardiographic pattern
J Electrocardiol
2009
42: 250-253
|
| 20144074 |
Li NF et al.:
Higher levels of plasma TNF-alpha and neuropeptide Y in hypertensive patients with obstructive sleep apnea syndrome
Clin. Exp. Hypertens.
2010
32: 54-60
|
| 18221481 |
Chang HM et al.:
Sleep deprivation predisposes liver to oxidative stress and phospholipid damage: a quantitative molecular imaging study
J. Anat.
2008
212: 295-305
|
| 22079349 |
Weiss JB et al.:
Anaplastic lymphoma kinase and leukocyte tyrosine kinase: functions and genetic interactions in learning, memory and adult neurogenesis
Pharmacol. Biochem. Behav.
2012
100: 566-574
|
| 19343201 |
Hughes ME et al.:
Harmonics of circadian gene transcription in mammals
PLoS Genet.
2009
5
|
| 20501693 |
Wang H et al.:
Computational analysis of gene regulation in animal sleep deprivation
Physiol. Genomics
2010
42: 427-436
|
| 19103603 |
Bailey MJ et al.:
Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling
J. Biol. Chem.
2009
284: 7606-7622
|
| 18945877 |
Bebas P et al.:
Circadian clock and output genes are rhythmically expressed in extratesticular ducts and accessory organs of mice
FASEB J.
2009
23: 523-533
|
| 16784547 |
Kramer A et al.:
Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signalling
Novartis Found. Symp.
2003
253: 250-262
|
| 16943549 |
Bandyopadhya RS et al.:
Activation of pedunculopontine tegmental protein kinase A: a mechanism for rapid eye movement sleep generation in the freely moving rat
J. Neurosci.
2006
26: 8931-8942
|
| 20093473 |
Robles MS et al.:
Identification of RACK1 and protein kinase Calpha as integral components of the mammalian circadian clock
Science
2010
327: 463-466
|
| 22105623 |
Allebrandt KV et al.:
A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila
Mol. Psychiatry
2013
18: 122-132
|
| 20300063 |
Wang X et al.:
Interaction of MAGED1 with nuclear receptors affects circadian clock function
EMBO J.
2010
29: 1389-1400
|
| 22112815 |
Dekker MJ et al.:
The effect of common genetic variation in 11beta-hydroxysteroid dehydrogenase type 1 on hypothalamic-pituitary-adrenal axis activity and incident depression
J. Clin. Endocrinol. Metab.
2012
97: E233-E237
|
| 16430724 |
Pecori Giraldi F et al.:
Effect of protracted treatment with rosiglitazone, a PPARgamma agonist, in patients with Cushings disease
Clin. Endocrinol. (Oxf)
2006
64: 219-224
|
| 2841611 |
Izumo S et al.:
Thyroid hormone receptor alpha isoforms generated by alternative splicing differentially activate myosin HC gene transcription
Nature
1988
334: 539-542
|
| 11884402 |
Sargsyan E et al.:
Identification of ERp29, an endoplasmic reticulum lumenal protein, as a new member of the thyroglobulin folding complex
J Biol Chem
2002
277
|
| 34470464 |
author information missing
article information missing
|
| 17164348 |
Tzachanis D et al.:
Twisted gastrulation (Tsg) is regulated by Tob and enhances TGF-beta signaling in activated T lymphocytes
Blood
2007
109: 2944-2952
|
| 24407161 |
Nakasone H et al. et al.:
Impact of high-/middle-molecular-weight adiponectin on the synthesis and regulation of extracellular matrix in dermal fibroblasts
Exp Hematol
2014
42: 261-273
|
| 26891860 |
Tsai SJ et al.:
Effects of interleukin-1beta polymorphisms on brain function and behavior in healthy and psychiatric disease conditions
Cytokine Growth Factor Rev.
2017
37: 89-97
|
| 30891856 |
Rytova V et al.:
Chronic activation of the relaxin-3 receptor on GABA neurons in rat ventral hippocampus promotes anxiety and social avoidance
Hippocampus
2019
29: 905-920
|
| 15730870 |
Jin M et al.:
The negative cell cycle regulator, Tob (transducer of ErbB-2), is a multifunctional protein involved in hippocampus-dependent learning and memory
Neuroscience
2005
131: 647-659
|
| 21466804 |
Trollope AF et al.:
Stress, epigenetic control of gene expression and memory formation
Exp. Neurol.
2012
233: 3-11
|
| 18923419 |
Ikushima H et al.:
An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-beta signalling
EMBO J.
2008
27: 2955-2965
|
| 10801854 |
Xia C et al.:
GCIP, a novel human grap2 and cyclin D interacting protein, regulates E2F-mediated transcriptional activity
J. Biol. Chem.
2000
275
|
| 21179169 |
Richly H et al.:
Transcriptional activation of polycomb-repressed genes by ZRF1
Nature
2010
468: 1124-1128
|
| 22990118 |
Woods NT et al.:
Charting the landscape of tandem BRCT domain-mediated protein interactions
Sci Signal
2012
5: RS6
|
| 17242925 |
Stark AD et al.:
Interaction of the novel antipsychotic aripiprazole with 5-HT1A and 5-HT 2A receptors: functional receptor-binding and in vivo electrophysiological studies
Psychopharmacology (Berl.)
2007
190: 373-382
|
| 6757812 |
Nelson DL et al.:
Central serotonergic receptors: evidence for heterogeneity and characterization by ligand-binding
Neurosci Biobehav Rev
1982
6: 499-502
|
| 16366516 |
Hirose T et al.:
Aripiprazole, a novel antipsychotic agent: dopamine D2 receptor partial agonist
J. Med. Invest.
2005
52: 284-290
|
| 17187964 |
Gietl A et al.:
ABCG1 gene variants in suicidal behavior and aggression-related traits
Eur Neuropsychopharmacol
2007
17: 410-416
|
| 19151710 |
Wallace DL et al.:
CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits
Nat. Neurosci.
2009
12: 200-209
|
| 19503748 |
Matsuo N et al.:
Comprehensive behavioral phenotyping of ryanodine receptor type 3 (RyR3) knockout mice: decreased social contact duration in two social interaction tests
Front Behav Neurosci
2009
3: 3
|
| 14730890 |
Pan YP et al.:
[mRNA expression alteration of two-pore potassium channels in the brain of beta-amyloid peptide25-35-induced memory impaired rats]
Yao Xue Xue Bao
2003
38: 721-724
|
| 23424202 |
Ufartes R et al.:
Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice
Hum. Mol. Genet.
2013
22: 2247-2262
|
| 23860750 |
author information missing
article information missing
|
| 24996399 |
Berger SM et al.:
The role of L-type voltage-gated calcium channels Ca1.2 and Ca 1.3 in normal and pathological brain function
|
| 21691274 |
Smith AK et al. et al.:
Association of a polymorphism in the indoleamine- 2,3-dioxygenase gene and interferon-alpha-induced depression in patients with chronic hepatitis C
Mol. Psychiatry
2012
17: 781-789
|
| 29118582 |
Shin KH et al.:
Association of TNF-alpha G-308A gene polymorphism with depression: a meta-analysis
Neuropsychiatr Dis Treat
2017
13: 2661-2668
|
| 20976279 |
Wieczorek L et al.:
Temporal and regional regulation of gene expression by calcium-stimulated adenylyl cyclase activity during fear memory
PLoS ONE
2010
5
|
| 29100089 |
Kury S et al. et al.:
De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability
Am. J. Hum. Genet.
2017
101: 768-788
|
| 24723470 |
Gautherot J et al.:
Phosphorylation of ABCB4 impacts its function: insights from disease-causing mutations
Hepatology
2014
60: 610-621
|
| 29958542 |
Furat Rencber S et al.:
Effect of resveratrol and metformin on ovarian reserve and ultrastructure in PCOS: an experimental study
J Ovarian Res
2018
11: 55
|
| 26488073 |
Temur M et al.:
Increased circulating urocortin-3 levels is associated with polycystic ovary syndrome
Gynecol. Endocrinol.
2016
32: 218-222
|
| 28914097 |
Kandaraki EA et al.:
Advanced glycation end products interfere in luteinizing hormone and follicle stimulating hormone signaling in human granulosa KGN cells
Exp Biol Med (Maywood)
2018
243: 29-33
|
| 32339379 |
Artimani T et al.:
APPL1 as an important regulator of insulin and adiponectin-signaling pathways in the PCOS: A narrative review
Cell Biol Int
2020
44: 1577-1587
|
| 22409835 |
Masud R et al.:
Gene expression profiling of peripheral blood mononuclear cells in the setting of peripheral arterial disease
J Clin Bioinforma
2012
2: 6
|
| 22911880 |
Boraska V et al.:
Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2012
159B: 803-811
|
| 27980695 |
Zhou F et al.:
Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis
Clin Epigenetics
2016
8: 131
|
| 28743926 |
Fischer H et al.:
Inactivation of DNase1L2 and DNase2 in keratinocytes suppresses DNA degradation during epidermal cornification and results in constitutive parakeratosis
Sci Rep
2017
7: 6433
|
| 28394916 |
Ueki M et al.:
Survey of single-nucleotide polymorphisms in the gene encoding human deoxyribonuclease I-like 2 producing loss of function potentially implicated in the pathogenesis of parakeratosis
PLoS ONE
2017
12
|
| 30997977 |
author information missing
Assessment of cardiac and vessel functions in childhood psoriasis }, authors { names ml { Saylan Cevik B, Akalin F, Erolu E, Gencosmanoglu S, Ergun T } }, from journal { title { iso-jta Turk J Med Sci, ml-jta Turk J Med Sci, issn 1303-6165, name Turkish journal of medical sciences }, imp { date std { year 2019, month 4, day 18 }, volume 49, issue 2, pages 617-623, language eng, pubstatus epublish, history { { pubstatus other, date std { year 2019, month 4, day 19, hour 6, minute 0 } }, { pubstatus pubmed, date std { year 2019, month 4, day 19, hour 6, minute 0 } }, { pubstatus medline, date std { year 2019, month 6, day 19, hour 6, minute 0 } } } } }, ids { pubmed 30997977, doi 10.3906/sag-1812-139, other { db ELocationID doi, tag str 10.3906/sag-1812-139 } } }, abstract Background/aim: Psoriasis is a chronic inflammatory disease. The effect of psoriasis on the cardiovascular system has not been studied in children before. We studied ventricular strain and vascular functions to assess early cardiovascular effects of psoriasis during childhood. Materials and methods: The study population consisted of 20 psoriatic and 20 age- and sex-matched control subjects. Two-dimensional echocardiography images, longitudinal and global strain, and carotid and brachial ultrasound studies were performed. Results: The mean age of psoriatic children was 14 +/- 0.89 years and that of the controls was 14.05 +/- 0.88. There were significant increases in terms of interventricular septum diastolic and left ventricular posterior wall diastolic diameter and decreases in mitral E, mitral A, and E/A values between groups. Tissue Doppler imaging revealed significant differences between groups in terms of lateral annulus E, A, E/A, isovolumetric contraction time, and ejection time. Aortic stiffness was significantly higher and global circumferential strain and longitudinal strain were significantly lower in the psoriasis group. Carotid intima media thickness and flow-mediated dilatation did not differ significantly between the groups. Conclusion: Cardiac left ventricular and arterial functions are affected in psoriatic children and may be an alarming sign of atherosclerotic heart disease in the long term. Early detection of these changes may be helpful for eliminating other risk factors
Turk J Med Sci
2019
49: 617-623
|
| 24005976 |
Debniak T et al.:
Common variants of ZNF750, RPTOR and TRAF3IP2 genes and psoriasis risk
Arch. Dermatol. Res.
2014
306: 231-238
|
| 29728633 |
Enerback C et al.:
The psoriasis-protective TYK2 I684S variant impairs IL-12 stimulated pSTAT4 response in skin-homing CD4+ and CD8+ memory T-cells
Sci Rep
2018
8: 7043
|
| 26513078 |
Mildner M et al.:
Matriptase-1 expression is lost in psoriatic skin lesions and is downregulated by TNFalpha in vitro
J Dtsch Dermatol Ges
2015
13: 1165-1174
|
| 31074061 |
Yu X et al.:
FGF19 sustains the high proliferative ability of keratinocytes in psoriasis through the regulation of Wnt/GSK-3beta/beta-catenin signalling via FGFR4
Clin Exp Pharmacol Physiol
2019
46: 761-769
|
| 7636313 |
author information missing
article information missing
|
| 23905195 |
Carlyle M et al.:
Treatment for Restless Legs Syndrome: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 86
|
| 22678064 |
DeAndrade MP et al.:
Motor restlessness, sleep disturbances, thermal sensory alterations and elevated serum iron levels in Btbd9 mutant mice
Hum. Mol. Genet.
2012
21: 3984-3992
|
| 26083613 |
Van Den Eeden SK et al.:
Risk of Cardiovascular Disease Associated with a Restless Legs Syndrome Diagnosis in a Retrospective Cohort Study from Kaiser Permanente Northern California
Sleep
2015
38: 1009-1015
|
| 19279021 |
Kemlink D et al. et al.:
Replication of restless legs syndrome loci in three European populations
J. Med. Genet.
2009
46: 315-318
|
| 31444227 |
Lyu S et al.:
The Role of BTBD9 in Striatum and Restless Legs Syndrome
|
| 21951159 |
Makino S et al.:
Plasma dehydroepiandrosterone sulphate and insulin-like growth factor I levels in obstructive sleep apnoea syndrome
Clin. Endocrinol. (Oxf)
2012
76: 593-601
|
| 21102985 |
Gharib SA et al.:
Intermittent hypoxia mobilizes bone marrow-derived very small embryonic-like stem cells and activates developmental transcriptional programs in mice
Sleep
2010
33: 1439-1446
|
| 23872455 |
Grace KP et al.:
K+ channel modulation causes genioglossus inhibition in REM sleep and is a strategy for reactivation
Respir Physiol Neurobiol
2013
188: 277-288
|
| 25811203 |
Hira HS et al.:
Plasma level of hypoxanthine/xanthine as markers of oxidative stress with different stages of obstructive sleep apnea syndrome
Ann Saudi Med
2014
34: 308-313
|
| 10563629 |
Simon DK et al.:
Familial multisystem degeneration with parkinsonism associated with the 11778 mitochondrial DNA mutation
Neurology
1999
8: 1787-1793
|
| 20301353 |
Pagon RA et al.:
Leber Hereditary Optic Neuropathy }, authors { names ml { Yu-Wai-Man P, Chinnery PF } }, from book { title { name GeneReviews(R) }, authors { names std { { name ml Pagon RA, role editor }, { name ml Adam MP, role editor }, { name ml Ardinger HH, role editor }, { name ml Wallace SE, role editor }, { name ml Amemiya A, role editor }, { name ml Bean LJH, role editor }, { name ml Bird TD, role editor }, { name ml Fong CT, role editor }, { name ml Mefford HC, role editor }, { name ml Smith RJH, role editor }, { name ml Stephens K, role editor } } }, imp { date std { year 1993 }, language eng, pubstatus ppublish, history { { pubstatus pubmed, date std { year 2010, month 3, day 20 } }, { pubstatus medline, date std { year 2010, month 3, day 20 } }, { pubstatus other, date std { year 2010, month 3, day 20 } } } } }, ids { pubmed 20301353, other { db bookaccession, tag str NBK1174 } } }, abstract Leber hereditary optic neuropathy (LHON) is characterized by bilateral, painless, subacute visual failure that develops during young adult life. Males are four to five times more likely than females to be affected. Affected individuals are usually entirely asymptomatic until they develop visual blurring affecting the central visual field in one eye; similar symptoms appear in the other eye an average of two to three months later. In about 25% of cases, visual loss is bilateral at onset. Visual acuity is severely reduced to counting fingers or worse in the majority of cases, and visual field testing shows an enlarging dense central or centrocecal scotoma. After the acute phase, the optic discs become atrophic. Significant improvements in visual acuity are rare and most persons qualify for registration as legally blind (visual acuity A, m.11778G>A, or m.14484T>C. Treatment of manifestations: Management of affected individuals is largely supportive, with the provision of visual aids, help with occupational rehabilitation, and registration with the relevant social services. ECG may reveal a pre-excitation syndrome in individuals harboring mtDNA LHON-causing mutations, but no further intervention is required in the absence of cardiac symptoms. A multidisciplinary approach to those affected individuals with extra-ocular neurologic features (ataxia, peripheral neuropathy and dystonia) should be considered to minimize the functional consequences of these complications. Agents/circumstances to avoid: Individuals harboring mtDNA LHON-causing mutations should be strongly advised to moderate their alcohol intake and not to smoke. Avoiding exposure to other putative environmental triggers for visual loss, in particular industrial toxins and drugs with mitochondrial-toxic effects, also seems reasonable. Therapies under investigation: A recent randomized controlled trial suggests that oral administration of idebenone could benefit individuals with LHON who are at an early stage of the disease process and still at high risk for further visual loss. Similarly, EPI-743 has been used in a small open-labelled study of five individuals with acute LHON with some early encouraging visual results. Leber hereditary optic neuropathy is caused by mutations in mtDNA and it is transmitted by maternal inheritance. Genetic counseling for LHON is complicated by the gender- and age-dependent penetrance of the primary mtDNA LHON-causing mutations. The mother of a proband usually has the mtDNA mutation and may or may not have symptoms. In most cases a history of visual loss affecting maternal relatives at a young age is present, but up to 40% of cases are simplex (i.e., occur in a single individual in a family). A male (affected or unaffected) with a primary LHON-causing mtDNA mutation cannot transmit the mutation to any of his offspring. A female (affected or unaffected) with a primary LHON-causing mtDNA mutation transmits the mutation to all of her offspring. Prenatal diagnosis for mitochondrial mutations is possible if the disease-causing mutation in a family is known; however, accurate interpretation of a positive prenatal test result is difficult because the mtDNA mutational load in amniocytes and chorionic villi may not correspond to that of other fetal or adult tissues, and the presence of the mtDNA mutation does not predict the occurrence of disease, age of onset, severity, or rate of disease progression. Prenatal testing may be available through laboratories offering testing for the gene of interest or custom testing
|
| 24568867 |
Behbehani R et al.:
ND4L gene concurrent 10609T>C and 10663T>C mutations are associated with Lebers hereditary optic neuropathy in a large pedigree from Kuwait
Br J Ophthalmol
2014
98: 826-831
|
| 20454697 |
Kumar M et al.:
Identification of novel mitochondrial mutations in Lebers hereditary optic neuropathy
Mol. Vis.
2010
16: 782-792
|
| 20149345 |
Allebrandt KV et al.:
CLOCK gene variants associate with sleep duration in two independent populations
Biol. Psychiatry
2010
67: 1040-1047
|
| 15858564 |
Cirelli C et al.:
Reduced sleep in Drosophila Shaker mutants
Nature
2005
434: 1087-1092
|
| 17694052 |
Foltenyi K et al.:
Activation of EGFR and ERK by rhomboid signaling regulates the consolidation and maintenance of sleep in Drosophila
Nat. Neurosci.
2007
10: 1160-1167
|
| 9644838 |
author information missing
article information missing
|
| 22778134 |
Yu Y et al.:
Neuronal Cbl controls biosynthesis of insulin-like peptides in Drosophila melanogaster
Mol. Cell. Biol.
2012
32: 3610-3623
|
| 16123311 |
author information missing
article information missing
|
| 24392270 |
Gast MT et al.:
The role of rs2237781 within GRM8 in eating behavior
Brain Behav
2013
3: 495-502
|
| 22931759 |
Tachikawa M et al.:
A clearance system for prostaglandin D2, a sleep-promoting factor, in cerebrospinal fluid: role of the blood-cerebrospinal barrier transporters
J. Pharmacol. Exp. Ther.
2012
343: 608-616
|
| 23440187 |
Moller-Levet CS et al.:
Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome
Proc. Natl. Acad. Sci. U.S.A.
2013
110
|
| 21325336 |
Liu C et al.:
PGC-1 coactivators in the control of energy metabolism
Acta Biochim. Biophys. Sin. (Shanghai)
2011
43: 248-257
|
| 26095975 |
Gillentine MA et al.:
The human clinical phenotypes of altered CHRNA7 copy number
Biochem. Pharmacol.
2015
97: 352-362
|
| 25077648 |
Lowther C et al.:
Delineating the 15q13.3 microdeletion phenotype: a case series and comprehensive review of the literature
Genet. Med.
2015
17: 149-157
|
| 32111193 |
Law S et al.:
Karyomegalic interstitial nephritis with a novel FAN1 gene mutation and concurrent ALECT2 amyloidosis
BMC Nephrol
2020
21: 74
|
| 29395075 |
Yin J et al. et al.:
Otud7a Knockout Mice Recapitulate Many Neurological Features of 15q13.3 Microdeletion Syndrome
Am. J. Hum. Genet.
2018
102: 296-308
|
| 31997314 |
Garret P et al. et al.:
Report of the first patient with a homozygous OTUD7A variant responsible for epileptic encephalopathy and related proteasome dysfunction
|
| 29395074 |
Uddin M et al. et al.:
OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome
Am. J. Hum. Genet.
2018
102: 278-295
|
| 31883789 |
Namba T et al. et al.:
Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis
|
| 30484771 |
Kalebic N et al.:
Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex
|
| 28045139 |
Yin J et al.:
Chrna7 deficient mice manifest no consistent neuropsychiatric and behavioral phenotypes
Sci Rep
2017
7: 39941
|
| 27853923 |
Gillentine MA et al. et al.:
The Cognitive and Behavioral Phenotypes of Individuals with CHRNA7 Duplications
J Autism Dev Disord
2017
47: 549-562
|
| 24849809 |
Lu B et al.:
alpha7 nicotinic acetylcholine receptor signaling inhibits inflammasome activation by preventing mitochondrial DNA release
Mol. Med.
2014
20: 350-358
|
| 25701707 |
Sinkus ML et al.:
The human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and function
Neuropharmacology
2015
96: 274-288
|
| 32050841 |
Liu W et al.:
MiR-211 protects cerebral ischemia/reperfusion injury by inhibiting cell apoptosis
Bioengineered
2020
11: 189-200
|
| 31589383 |
He Y et al. et al.:
Long non-coding RNA GAPLINC promotes angiogenesis by regulating miR-211 under hypoxia in human umbilical vein endothelial cells
J. Cell. Mol. Med.
2019
23: 8090-8100
|
| 31542097 |
Chen CP et al.:
Detection of de novo del(18)(q22.2) and a familial of 15q13.2-q13.3 microduplication in a fetus with congenital heart defects
Taiwan J Obstet Gynecol
2019
58: 704-708
|
| 27459725 |
Forsingdal A et al.:
15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes
Transl Psychiatry
2016
6: e860
|
| 27451392 |
Cruz-Topete D et al.:
Kruppel-like Factor 13 Is a Major Mediator of Glucocorticoid Receptor Signaling in Cardiomyocytes and Protects These Cells from DNA Damage and Death
J. Biol. Chem.
2016
291
|
| 19372089 |
van Bon BW et al. et al.:
Further delineation of the 15q13 microdeletion and duplication syndromes: a clinical spectrum varying from non-pathogenic to a severe outcome
J. Med. Genet.
2009
46: 511-523
|
| 21596161 |
Spielmann M et al.:
Homozygous deletion of chromosome 15q13.3 including CHRNA7 causes severe mental retardation, seizures, muscular hypotonia, and the loss of KLF13 and TRPM1 potentially cause macrocytosis and congenital retinal dysfunction in siblings
Eur J Med Genet
2011
54: e441-e445
|
| 26658876 |
Kogan JH et al. et al.:
Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder
J. Neurosci.
2015
35
|
| 20378606 |
Chen J et al.:
A functional variant in the 3-UTR of angiopoietin-1 might reduce stroke risk by interfering with the binding efficiency of microRNA 211
Hum. Mol. Genet.
2010
19: 2524-2533
|
| 28790168 |
Zhang K et al.:
MicroRNA-211/BDNF axis regulates LPS-induced proliferation of normal human astrocyte through PI3K/AKT pathway
|
| 18285334 |
Gordon AR et al.:
Splenomegaly and modified erythropoiesis in KLF13-/- mice
J. Biol. Chem.
2008
283
|
| 19436059 |
Oancea E et al.:
TRPM1 forms ion channels associated with melanin content in melanocytes
Sci Signal
2009
2: ra21
|
| 21245375 |
Li J et al.:
Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling
Mol. Cell. Biol.
2011
31: 1134-1144
|
| 23266623 |
Duno M et al.:
A novel mitochondrial mutation m.8989G>C associated with neuropathy, ataxia, retinitis pigmentosa - the NARP syndrome
Gene
2013
515: 372-375
|
| 20953793 |
Gelfand JM et al.:
Heterogeneous patterns of tissue injury in NARP syndrome
J. Neurol.
2011
258: 440-448
|
| 25746071 |
Miyawaki T et al.:
[A case of neurologic muscle weakness, ataxia, and retinitis pigmentosa (NARP) syndrome with a novel mitochondrial mutation m.8729 G>A]
Rinsho Shinkeigaku
2015
55: 91-95
|
| 18261463 |
Dassa EP et al.:
The mtDNA NARP mutation activates the actin-Nrf2 signaling of antioxidant defenses
Biochem. Biophys. Res. Commun.
2008
368: 620-624
|
| 18461509 |
Childs AM et al.:
Variable phenotype including Leigh syndrome with a 9185T>C mutation in the MTATP6 gene
Neuropediatrics
2007
38: 313-316
|
| 24118886 |
Blanco-Grau A et al.:
Identification and biochemical characterization of the novel mutation m.8839G>C in the mitochondrial ATP6 gene associated with NARP syndrome
Genes Brain Behav.
2013
12: 812-820
|
| 25051967 |
Dweikat IM et al.:
MEGDEL Syndrome in a Child From Palestine: Report of a Novel Mutation in SERAC1 Gene
|
| 12469120 |
Roetto A et al.:
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
Nat. Genet.
2003
33: 21-22
|
| 15198949 |
Matthes T et al.:
Severe hemochromatosis in a Portuguese family associated with a new mutation in the 5-UTR of the HAMP gene
Blood
2004
104: 2181-2183
|
| 11389486 |
Kato J et al.:
A mutation, in the iron-responsive element of H ferritin mRNA, causing autosomal dominant iron overload
Am. J. Hum. Genet.
2001
69: 191-197
|
| 25444000 |
Heissat S et al.:
Neonatal hemochromatosis: diagnostic work-up based on a series of 56 cases of fetal death and neonatal liver failure
J. Pediatr.
2015
166: 66-73
|
| 22729392 |
Belostotsky R et al.:
Primary hyperoxaluria type III--a model for studying perturbations in glyoxylate metabolism
J. Mol. Med.
2012
90: 1497-1504
|
| 24563386 |
Pitt JJ et al.:
4-hydroxyglutamate is a biomarker for primary hyperoxaluria type 3
JIMD Rep
2015
15: 1-6
|
| 20206689 |
Sanaker PS et al.:
Differences in RNA processing underlie the tissue specific phenotype of ISCU myopathy
Biochim. Biophys. Acta
2010
1802: 539-544
|
| 23943793 |
Crooks DR et al.:
Elevated FGF21 secretion, PGC-1alpha and ketogenic enzyme expression are hallmarks of iron-sulfur cluster depletion in human skeletal muscle
Hum. Mol. Genet.
2014
23: 24-39
|
| 21079607 |
Wang K et al.:
A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa
Mol. Psychiatry
2011
16: 949-959
|
| 16118784 |
Michaelovsky E et al. et al.:
Haplotype analysis of the COMT-ARVCF gene region in Israeli anorexia nervosa family trios
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2005
139B: 45-50
|
| 21470430 |
Pimentel-Santos FM et al. et al.:
Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive disease aspects
Arthritis Res. Ther.
2011
13: R57
|
| 19798636 |
Suls A et al.:
Early-onset absence epilepsy caused by mutations in the glucose transporter GLUT1.
Ann. Neurol.
2009
66: 415-419
|
| 19798636 |
Suls A et al.:
Early-onset absence epilepsy caused by mutations in the glucose transporter GLUT1
Ann. Neurol.
2009
66: 415-419
|
| 25754594 |
Vetro A et al. et al.:
Loss-of-Function FANCL Mutations Associate with Severe Fanconi Anemia Overlapping the VACTERL Association
Hum Mutat
2015
36: 562-568
|
| 23958962 |
Gelernter J et al.:
Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene
Mol Psychiatry
2014
19: 717-723
|
| 25356899 |
Hamdan FF et al. et al.:
De novo mutations in moderate or severe intellectual disability
PLoS Genet.
2014
10
|
| 25626716 |
Bulayeva K et al.:
Genomic structural variants are linked with intellectual disability
J Neural Transm (Vienna)
2015
122: 1289-1301
|
| 26350204 |
Grozeva D et al. et al.:
Targeted Next-Generation Sequencing Analysis of 1,000 Individuals with Intellectual Disability
Hum. Mutat.
2015
36: 1197-1204
|
| 31721002 |
Ben-Mahmoud A et al.:
Evaluating the Role of MAST1 as an Intellectual Disability Disease Gene: Identification of a Novel De Novo Variant in a Patient with Developmental Disabilities
J. Mol. Neurosci.
2020
70: 320-327
|
| 31495922 |
Qu R et al.:
A homozygous mutation in CMAS causes autosomal recessive intellectual disability in a Kazakh family
Ann Hum Genet
2020
84: 46-53
|
| 34244665 |
author information missing
article information missing
|
| 26280581 |
author information missing
Analysis of conditional heterozygous STXBP1 mutations in human neurons
J. Clin. Invest.
2015
125: 3560-3571
|
| 18469812 |
Saitsu H et al. et al.:
De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy
Nat. Genet.
2008
40: 782-788
|
| 29191246 |
Hamada N et al.:
MUNC18-1 gene abnormalities are involved in neurodevelopmental disorders through defective cortical architecture during brain development
Acta Neuropathol Commun
2017
5: 92
|
| 10208283 |
Nagashima T et al.:
Adult Leigh syndrome with mitochondrial DNA mutation at 8993
Acta Neuropathol.
1999
97: 416-422
|
| 21819970 |
Ronchi D et al.:
Unusual adult-onset Leigh syndrome presentation due to the mitochondrial m.9176T>C mutation
Biochem. Biophys. Res. Commun.
2011
412: 245-248
|
| 23615070 |
Lopez-Rodriguez R et al.:
Polymorphisms in histone deacetylases improve the predictive value of IL-28B for chronic hepatitis C therapy
Genes Immun.
2013
14: 317-324
|
| 9389040 |
Li P et al.:
[The value of determining guanine deaminase in diagnosis of hepatic diseases]
Hua Xi Yi Ke Da Xue Xue Bao
1996
27: 189-191
|
| 32379894 |
Li J et al.:
Association between ABO blood groups and risk of SARS-CoV-2 pneumonia
Br. J. Haematol.
2020
190: 24-27
|
| 21261723 |
Fabris C et al.:
Apolipoprotein E genotypes modulate fibrosis progression in patients with chronic hepatitis C and persistently normal transaminases
J. Gastroenterol. Hepatol.
2011
26: 328-333
|
| 26880346 |
Mueller T et al. et al.:
Apolipoprotein E allele frequencies in chronic and self-limited hepatitis C suggest a protective effect of APOE4 in the course of hepatitis C virus infection
Liver Int
2016
36: 1267-1274
|
| 12143056 |
Wozniak MA et al.:
Apolipoprotein E-epsilon 4 protects against severe liver disease caused by hepatitis C virus
Hepatology
2002
36: 456-463
|
| 26136767 |
Venco P et al.:
Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca(2)(+)
Front Genet
2015
6: 185
|
| 21981780 |
Hartig MB et al.:
Absence of an orphan mitochondrial protein, c19orf12, causes a distinct clinical subtype of neurodegeneration with brain iron accumulation
Am. J. Hum. Genet.
2011
89: 543-550
|
| 32935446 |
He B et al.:
Continuous spectrum of glucose dysmetabolism due to the KCNJ11 gene mutation-Case reports and review of the literature
J Diabetes
2021
13: 19-32
|
| 25208612 |
Haghighi A et al.:
Sengers syndrome: six novel AGK mutations in seven new families and review of the phenotypic and mutational spectrum of 29 patients
Orphanet J Rare Dis
2014
9: 119
|
| 28867158 |
Martensson CU et al.:
Acylglycerol Kinase: Mitochondrial Protein Transport Meets Lipid Biosynthesis
Trends Cell Biol
2017
27: 700-702
|
| 28620038 |
Diggins NL et al.:
APPL1 is a multifunctional endosomal signaling adaptor protein
Biochem Soc Trans
2017
45: 771-779
|
| 29483192 |
Galan-Davila AK et al. et al.:
Alternative splicing variant of the scaffold protein APPL1 suppresses hepatic adiponectin signaling and function
J Biol Chem
2018
293: 6064-6074
|
| 32854233 |
Ivanoshchuk DE et al.:
Analysis of APPL1 Gene Polymorphisms in Patients with a Phenotype of Maturity Onset Diabetes of the Young
|
| 31206806 |
Gaspar RC et al. et al.:
Acute physical exercise increases APPL1/PI3K signaling in the hypothalamus of lean mice
Eur J Neurosci
2019
50: 3181-3190
|
| 22685329 |
Hupalowska A et al.:
APPL1 regulates basal NF-kappaB activity by stabilizing NIK
J Cell Sci
2012
125: 4090-4102
|
| 19598069 |
Menegatti M et al.:
Factor X deficiency
Semin. Thromb. Hemost.
2009
4: 407-415
|
| 3896125 |
et al.:
Vitamin K-dependent carboxylase
Annu. Rev. Biochem.
1985
54: 459-477
|
| 10688334 |
Himmelspach M et al.:
Recombinant human factor X: high yield expression and the role of furin in proteolytic maturation in vivo and in vitro
Thromb. Res.
2000
2: 51-67
|
| 22818555 |
et al.:
Brief overview of the coagulation cascade
Dis Mon
2012
8: 421-423
|
| 14622600 |
Feldmann J et al.:
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)
Cell
2003
115: 461-473
|
| 11641223 |
de Iongh RU et al.:
Requirement for TGFbeta receptor signaling during terminal lens fiber differentiation
Development
2001
20: 3995-4010
|
| 19587458 |
Song S et al.:
Functions of the intermediate filament cytoskeleton in the eye lens
J. Clin. Invest.
2009
119: 1837-1848
|
| 16565358 |
Bidinost C et al.:
Heterozygous and homozygous mutations in PITX3 in a large Lebanese family with posterior polar cataracts and neurodevelopmental abnormalities
Invest. Ophthalmol. Vis. Sci.
2006
47: 1274-1280
|
| 25576668 |
Zhao G et al.:
Negative regulation of TGFbeta-induced lens epithelial to mesenchymal transition (EMT) by RTK antagonists
Exp. Eye Res.
2015
132: 9-16
|
| 19649315 |
Jun G et al. et al.:
EPHA2 is associated with age-related cortical cataract in mice and humans
PLoS Genet
2009
5
|
| 18948590 |
Cooper MA et al.:
Loss of ephrin-A5 function disrupts lens fiber cell packing and leads to cataract
Proc Natl Acad Sci U S A
2008
105
|
| 12750 |
et al.:
Effect of phenylalanine metabolites on the activities of enzymes of ketone-body utilization in brain of suckling rats
Biochem. J.
1976
2: 217-222
|
| 5260939 |
author information missing
Inhibition of human brain pyruvate kinase and hexokinase by phenylalanine and phenylpyruvate: possible relevance to phenylketonuric brain damage
Proc. Natl. Acad. Sci. U.S.A.
1969
63: 1365-1369
|
| 11522273 |
author information missing
article information missing
|
| 27895387 |
Miyamoto Y et al.:
Retention of acetylcarnitine in chronic kidney disease causes insulin resistance in skeletal muscle
J Clin Biochem Nutr
2016
59: 199-206
|
| 24797667 |
Andrukhova O et al.:
FGF23 regulates renal sodium handling and blood pressure
EMBO Mol Med
2014
6: 744-759
|
| 22647968 |
Andrukhova O et al.:
FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway
Bone
2012
51: 621-628
|
| 19966287 |
Goetz R et al.:
Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 407-412
|
| 24434184 |
Andrukhova O et al.:
FGF23 promotes renal calcium reabsorption through the TRPV5 channel
EMBO J.
2014
33: 229-246
|
| 28302371 |
McMahon GM et al.:
Urinary metabolites along with common and rare genetic variations are associated with incident chronic kidney disease
Kidney Int.
2017
91: 1426-1435
|
| 21115613 |
Hu MC et al.:
Klotho deficiency causes vascular calcification in chronic kidney disease
J. Am. Soc. Nephrol.
2011
22: 124-136
|
| 24911970 |
Hsu SC et al.:
Resveratrol increases anti-aging Klotho gene expression via the activating transcription factor 3/c-Jun complex-mediated signaling pathway
Int. J. Biochem. Cell Biol.
2014
53: 361-371
|
| 28397744 |
Cheng Z et al.:
MMP-2 and 9 in Chronic Kidney Disease
|
| 19357253 |
Larman BW et al.:
Chordin-like 1 and twisted gastrulation 1 regulate BMP signaling following kidney injury
J. Am. Soc. Nephrol.
2009
20: 1020-1031
|
| 29554320 |
Gil RB et al.:
Increased urinary osmolyte excretion indicates chronic kidney disease severity and progression rate
|
| 29573704 |
Huang M et al.:
The uremic toxin hippurate promotes endothelial dysfunction via the activation of Drp1-mediated mitochondrial fission
Redox Biol
2018
16: 303-313
|
| 26342724 |
Arafa E et al.:
TMIGD1 is a novel adhesion molecule that protects epithelial cells from oxidative cell injury
Am. J. Pathol.
2015
185: 2757-2767
|
| 32303178 |
Hartmann C et al.:
The mitochondrial outer membrane protein SYNJ2BP interacts with the cell adhesion molecule TMIGD1 and can recruit it to mitochondria
BMC Mol Cell Biol
2020
21: 30
|
| 31165585 |
Stoll D et al.:
Both aldosterone and spironolactone can modulate the intracellular ACE/ANG II/AT1 and ACE2/ANG (1-7)/MAS receptor axes in human mesangial cells
Physiol Rep
2019
7
|
| 10972684 |
Brown NJ et al.:
Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo
Kidney Int.
2000
58: 1219-1227
|
| 1338730 |
Aguilera G et al.:
Role of angiotensin II receptor subtypes on the regulation of aldosterone secretion in the adrenal glomerulosa zone in the rat
Mol. Cell. Endocrinol.
1992
90: 53-60
|
| 30181742 |
Vahdat S et al.:
The complex effects of adipokines in the patients with kidney disease
J Res Med Sci
2018
23: 60
|
| 21613803 |
Petrova DT et al.:
Differential kidney proteome profiling in a murine model of renal fibrosis under treatment with mycophenolate mofetil
Pathobiology
2011
78: 162-170
|
| 31015462 |
Graham SE et al. et al.:
Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis
Nat Commun
2019
10: 1847
|
| 32505465 |
Schonauer R et al. et al.:
Novel nephronophthisis-associated variants reveal functional importance of MAPKBP1 dimerization for centriolar recruitment
Kidney Int
2020
98: 958-969
|
| 8113390 |
Miyata T et al.:
Involvement of beta 2-microglobulin modified with advanced glycation end products in the pathogenesis of hemodialysis-associated amyloidosis. Induction of human monocyte chemotaxis and macrophage secretion of tumor necrosis factor-alpha and interleukin-1
J Clin Invest
1994
93: 521-528
|
| 10652049 |
Matsuo K et al.:
Transforming growth factor-beta is involved in the pathogenesis of dialysis-related amyloidosis
Kidney Int
2000
57: 697-708
|
| 30740857 |
Swystun LL et al.:
The endothelial lectin clearance receptor CLEC4M binds and internalizes factor VIII in a VWF-dependent and independent manner
J Thromb Haemost
2019
17: 681-694
|
| 29653105 |
Kim YI et al.:
CST3 and GDF15 ameliorate renal fibrosis by inhibiting fibroblast growth and activation
Biochem Biophys Res Commun
2018
500: 288-295
|
| 11737589 |
Uchiyama-Tanaka Y et al. et al.:
Angiotensin II signaling and HB-EGF shedding via metalloproteinase in glomerular mesangial cells
Kidney Int
2001
60: 2153-2163
|
| 25049200 |
Martinez Cantarin MP et al.:
Adiponectin receptor and adiponectin signaling in human tissue among patients with end-stage renal disease
Nephrol Dial Transplant
2014
29: 2268-2277
|
| 17513431 |
Kopple JD et al.:
Phenylalanine and tyrosine metabolism in chronic kidney failure
J Nutr
2007
137: 1586
|
| 21997736 |
Qiu J et al.:
Insulin-like growth factor binding protein-6 interacts with the thyroid hormone receptor alpha1 and modulates the thyroid hormone-response in osteoblastic differentiation
Mol Cell Biochem
2012
361: 197-208
|
| 29987860 |
Tanaka K et al. et al.:
Renal expression of trefoil factor 3 mRNA in association with tubulointerstitial fibrosis in IgA nephropathy
Nephrology (Carlton)
2018
23: 855-862
|
| 15561974 |
Xu H et al.:
EphA2: expression in the renal medulla and regulation by hypertonicity and urea stress in vitro and in vivo
Am J Physiol Renal Physiol
2005
288: F855-F866
|
| 27228995 |
Rodriguez S et al.:
Bidirectional signalling between EphA2 and ephrinA1 increases tubular cell attachment, laminin secretion and modulates erythropoietin expression after renal hypoxic injury
Pflugers Arch
2016
468: 1433-1448
|
| 31545926 |
Bai M et al. et al.:
BMP1 inhibitor UK383,367 attenuates renal fibrosis and inflammation in CKD
Am J Physiol Renal Physiol
2019
317
|
| 30541139 |
Valino-Rivas L et al.:
MAGE genes in the kidney: identification of MAGED2 as upregulated during kidney injury and in stressed tubular cells
Nephrol Dial Transplant
2019
34: 1498-1507
|
| 25885044 |
Thameem F et al.:
Evaluation of neurotrophic tyrosine receptor kinase 2 (NTRK2) as a positional candidate gene for variation in estimated glomerular filtration rate (eGFR) in Mexican American participants of San Antonio Family Heart study
J Biomed Sci
2015
22: 23
|
| 32958645 |
Ngo D et al. et al.:
Circulating testican-2 is a podocyte-derived marker of kidney health
Proc Natl Acad Sci U S A
2020
117
|
| 18971211 |
Mu W et al.:
Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism
Am J Physiol Renal Physiol
2009
296: F145-F152
|
| 28339962 |
Kralisch S et al. et al.:
FSTL3 is increased in renal dysfunction
Nephrol Dial Transplant
2017
32: 1637-1644
|
| 26410531 |
Adachi T et al.:
Roles of layilin in TNF-alpha-induced epithelial-mesenchymal transformation of renal tubular epithelial cells
Biochem Biophys Res Commun
2015
467: 63-69
|
| 28751525 |
Han SH et al.:
PGC-1alpha Protects from Notch-Induced Kidney Fibrosis Development
J Am Soc Nephrol
2017
28: 3312-3322
|
| 2517676 |
Druml W et al.:
Phenylalanine and tyrosine metabolism in renal failure: dipeptides as tyrosine source
Kidney Int Suppl
1989
27: S282-S286
|
| 24352503 |
Grabias BM et al.:
The physical basis of renal fibrosis: effects of altered hydrodynamic forces on kidney homeostasis
Am J Physiol Renal Physiol
2014
306: F473-F485
|
| 16585060 |
Rastaldi MP et al. et al.:
Glomerular podocytes contain neuron-like functional synaptic vesicles
FASEB J
2006
20: 976-978
|
| 31688840 |
Wisniewska M et al.:
Chronic kidney disease is associated with increased levels of renalase in serum and decreased in erythrocytes
Pol Arch Intern Med
2019
129: 790-797
|
| 33416889 |
Martinez-Arias L et al. et al.:
Effects of calcitriol and paricalcitol on renal fibrosis in CKD
|
| 31048445 |
Smyth LJ et al.:
Genetic associations between genes in the renin-angiotensin-aldosterone system and renal disease: a systematic review and meta-analysis
BMJ Open
2019
9
|
| 9839282 |
Ruiz-Ortega M et al.:
Angiotensin III up-regulates genes involved in kidney damage in mesangial cells and renal interstitial fibroblasts
Kidney Int Suppl
1998
68: S41-S45
|
| 10844599 |
Ruiz-Ortega M et al.:
Angiotensin III increases MCP-1 and activates NF-kappaB and AP-1 in cultured mesangial and mononuclear cells
Kidney Int
2000
57: 2285-2298
|
| 23564382 |
Hamada K et al. et al.:
Serum level of soluble (pro)renin receptor is modulated in chronic kidney disease
Clin Exp Nephrol
2013
17: 848-856
|
| 21249398 |
Al-Ismaili Z et al.:
Rhabdomyolysis: pathogenesis of renal injury and management
Pediatr Nephrol
2011
26: 1781-1788
|
| 26011469 |
author information missing
article information missing
|
| 29519950 |
author information missing
article information missing
|
| 33428023 |
author information missing
article information missing
|
| 25419705 |
author information missing
article information missing
|
| 16168195 |
author information missing
article information missing
|
| 23739151 |
author information missing
article information missing
|
| 16567268 |
author information missing
article information missing
|
| 7545697 |
author information missing
article information missing
|
| 28754554 |
author information missing
article information missing
|
| 24714768 |
author information missing
article information missing
|
| 33558182 |
author information missing
article information missing
|
| 34603081 |
author information missing
article information missing
|
| 19136951 |
Rutsch F et al.:
Identification of a putative lysosomal cobalamin exporter altered in the cblF defect of vitamin B12 metabolism
Nat. Genet.
2009
41: 234-239
|
| 19447654 |
Hannibal L et al.:
Processing of alkylcobalamins in mammalian cells: A role for the MMACHC (cblC) gene product
Mol. Genet. Metab.
2009
97: 260-266
|
| 18779575 |
Kim J et al.:
Decyanation of vitamin B12 by a trafficking chaperone
Proc. Natl. Acad. Sci. U.S.A.
2008
105
|
| 23270877 |
Mah W et al.:
Subcellular location of MMACHC and MMADHC, two human proteins central to intracellular vitamin B(12) metabolism
Mol. Genet. Metab.
2013
108: 112-118
|
| 28497574 |
Plessl T et al.:
Protein destabilization and loss of protein-protein interaction are fundamental mechanisms in cblA-type methylmalonic aciduria
|
| 26483544 |
Froese DS et al.:
Structural Insights into the MMACHC-MMADHC Protein Complex Involved in Vitamin B12 Trafficking
J. Biol. Chem.
2015
290
|
| 23539619 |
Gherasim C et al.:
Navigating the B(12) road: assimilation, delivery, and disorders of cobalamin
J. Biol. Chem.
2013
288
|
| 2566828 |
Walter JH et al.:
Contribution of aminoacid catabolism to propionate production in methylmalonic acidaemia
Lancet
1989
1: 1298-1299
|
| 27519416 |
Forny P et al.:
Novel Mouse Models of Methylmalonic Aciduria Recapitulate Phenotypic Traits with a Genetic Dosage Effect
J. Biol. Chem.
2016
291
|
| 28395089 |
Gabbi P et al.:
Methylmalonate Induces Inflammatory and Apoptotic Potential: A Link to Glial Activation and Neurological Dysfunction
J. Neuropathol. Exp. Neurol.
2017
76: 160-178
|
| 26420839 |
Ruppert T et al.:
Molecular and biochemical alterations in tubular epithelial cells of patients with isolated methylmalonic aciduria
Hum. Mol. Genet.
2015
24: 7049-7059
|
| 19342984 |
de Keyzer Y et al.:
Multiple OXPHOS deficiency in the liver, kidney, heart, and skeletal muscle of patients with methylmalonic aciduria and propionic aciduria
Pediatr. Res.
2009
66: 91-95
|
| 17846917 |
Morath MA et al.:
Neurodegeneration and chronic renal failure in methylmalonic aciduria--a pathophysiological approach
J. Inherit. Metab. Dis.
2008
31: 35-43
|
| 16324816 |
Pettenuzzo LF et al.:
Differential inhibitory effects of methylmalonic acid on respiratory chain complex activities in rat tissues
Int. J. Dev. Neurosci.
2006
24: 45-52
|
| 26800654 |
Amaral AU et al.:
2-Methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria
J. Neurochem.
2016
137: 62-75
|
| 24095221 |
Haarmann A et al.:
Renal involvement in a patient with cobalamin A type (cblA) methylmalonic aciduria: a 42-year follow-up
Mol. Genet. Metab.
2013
110: 472-476
|
| 22583396 |
Goyenechea E et al.:
Expression of proinflammatory factors in renal cortex induced by methylmalonic acid
Ren Fail
2012
34: 885-891
|
| 27599447 |
Cudre-Cung HP et al.:
Ammonium accumulation is a primary effect of 2-methylcitrate exposure in an in vitro model for brain damage in methylmalonic aciduria
Mol. Genet. Metab.
2016
119: 57-67
|
| 24798023 |
Li Y et al.:
MicroRNA-9 regulates neural apoptosis in methylmalonic acidemia via targeting BCL2L11
Int. J. Dev. Neurosci.
2014
36: 19-24
|
| 24580146 |
Viegas CM et al.:
Disruption of redox homeostasis and brain damage caused in vivo by methylmalonic acid and ammonia in cerebral cortex and striatum of developing rats
Free Radic. Res.
2014
48: 659-669
|
| 6723070 |
author information missing
Propionylcarnitine excretion in propionic and methylmalonic acidurias: a cause of carnitine deficiency
Clin. Chim. Acta
1984
139: 13-21
|
| 2919129 |
Wendel U et al.:
Abnormality of odd-numbered long-chain fatty acids in erythrocyte membrane lipids from patients with disorders of propionate metabolism
Pediatr. Res.
1989
25: 147-150
|
| 25585586 |
Caterino M et al.:
The proteome of cblC defect: in vivo elucidation of altered cellular pathways in humans
J. Inherit. Metab. Dis.
2015
38: 969-979
|
| 25526710 |
Huemer M et al.:
Clinical onset and course, response to treatment and outcome in 24 patients with the cblE or cblG remethylation defect complemented by genetic and in vitro enzyme study data
J. Inherit. Metab. Dis.
2015
38: 957-967
|
| 38924428 |
author information missing
article information missing
|
| 16686602 |
Schwab MA et al.:
Secondary mitochondrial dysfunction in propionic aciduria: a pathogenic role for endogenous mitochondrial toxins
Biochem. J.
2006
398: 107-112
|
| 17951291 |
Wikoff WR et al.:
Metabolomics identifies perturbations in human disorders of propionate metabolism
Clin. Chem.
2007
53: 2169-2176
|
| 29033250 |
Wongkittichote P et al.:
Propionyl-CoA carboxylase - A review
Mol. Genet. Metab.
2017
122: 145-152
|
| 28720782 |
Rivera-Barahona A et al.:
Dysregulated miRNAs and their pathogenic implications for the neurometabolic disease propionic acidemia
Sci Rep
2017
7: 5727
|
| 21951809 |
Del Valle-Pinero AY et al.:
Pro-inflammatory chemokine C-C motif ligand 16 (CCL-16) dysregulation in irritable bowel syndrome (IBS): a pilot study
Neurogastroenterol. Motil.
2011
23: 1092-1097
|
| 14988808 |
Huck JH et al.:
Ribose-5-phosphate isomerase deficiency: new inborn error in the pentose phosphate pathway associated with a slowly progressive leukoencephalopathy
Am. J. Hum. Genet.
2004
74: 745-751
|
| 16435188 |
Wamelink MM et al.:
Analysis of polyols in urine by liquid chromatography-tandem mass spectrometry: a useful tool for recognition of inborn errors affecting polyol metabolism
J. Inherit. Metab. Dis.
2005
28: 951-963
|
| 24497183 |
Tylki-Szymanska A et al.:
Clinical and molecular characteristics of two transaldolase-deficient patients
Eur. J. Pediatr.
2014
173: 1679-1682
|
| 26182429 |
Imbard A et al.:
High homocysteine induces betaine depletion
|
| 17436311 |
Fredriksen A et al.:
Large-scale population-based metabolic phenotyping of thirteen genetic polymorphisms related to one-carbon metabolism
Hum. Mutat.
2007
28: 856-865
|
| 28193546 |
Conley SM et al.:
Contribution of guanine nucleotide exchange factor Vav2 to NLRP3 inflammasome activation in mouse podocytes during hyperhomocysteinemia
Free Radic. Biol. Med.
2017
106: 236-244
|
| 24475090 |
Kim K et al.:
Mealtime, temporal, and daily variability of the human urinary and plasma metabolomes in a tightly controlled environment
PLoS ONE
2014
9
|
| 25805165 |
Vanzin CS et al.:
Lipid, Oxidative and Inflammatory Profile and Alterations in the Enzymes Paraoxonase and Butyrylcholinesterase in Plasma of Patients with Homocystinuria Due CBS Deficiency: The Vitamin B12 and Folic Acid Importance
Cell. Mol. Neurobiol.
2015
35: 899-911
|
| 16425363 |
Bene J et al.:
Plasma carnitine ester profile in adult celiac disease patients maintained on long-term gluten free diet
World J. Gastroenterol.
2005
11: 6671-6675
|
| 24453145 |
Prasad M et al.:
Glutaric aciduria type II presenting as myopathy and rhabdomyolysis in a teenager
J. Child Neurol.
2015
30: 96-99
|
| 28516284 |
Nochi Z et al.:
Short-chain acyl-CoA dehydrogenase deficiency: from gene to cell pathology and possible disease mechanisms
J. Inherit. Metab. Dis.
2017
40: 641-655
|
| 23800285 |
Hildebrandt TM et al.:
Proteome adaptations in Ethe1-deficient mice indicate a role in lipid catabolism and cytoskeleton organization via post-translational protein modifications
|
| 20528888 |
Drousiotou A et al.:
Ethylmalonic encephalopathy: application of improved biochemical and molecular diagnostic approaches
Clin. Genet.
2011
79: 385-390
|
| 27074420 |
Sahebekhtiari N et al.:
Untargeted Metabolomics Analysis Reveals a Link between ETHE1-Mediated Disruptive Redox State and Altered Metabolic Regulation
J. Proteome Res.
2016
15: 1630-1638
|
| 27259054 |
Boyle L et al.:
Mutations in TKT Are the Cause of a Syndrome Including Short Stature, Developmental Delay, and Congenital Heart Defects
Am. J. Hum. Genet.
2016
98: 1235-1242
|
| 25647543 |
Wamelink MM et al.:
First two unrelated cases of isolated sedoheptulokinase deficiency: A benign disorder? }, authors { names std { { name ml Wamelink MM, affil str Department of Clinical Chemistry, Neuroscience Campus Amsterdam, VU University Medical Center, De Boelelaan 1117, 1081HV, Amsterdam, The Netherlands, m.wamelink@vumc.nl
J. Inherit. Metab. Dis.
2015
38: 889-894
|
| 18775706 |
Kardon T et al.:
Characterization of mammalian sedoheptulokinase and mechanism of formation of erythritol in sedoheptulokinase deficiency
FEBS Lett.
2008
582: 3330-3334
|
| 22682222 |
Haschemi A et al.:
The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism
Cell Metab.
2012
15: 813-826
|
| 23514175 |
Nagy C et al.:
Sedoheptulose kinase regulates cellular carbohydrate metabolism by sedoheptulose 7-phosphate supply
Biochem. Soc. Trans.
2013
41: 674-680
|
| 16901854 |
Sreenath K et al.:
Generation of an antibody specific to erythritol, a non-immunogenic food additive
Food Addit Contam
2006
23: 861-869
|
| 10774141 |
Hino H et al.:
A case of allergic urticaria caused by erythritol
J. Dermatol.
2000
27: 163-165
|
| 11590396 |
et al.:
Allergic reactions after ingestion of erythritol-containing foods and beverages
J. Allergy Clin. Immunol.
2001
108: 650
|
| 27255477 |
Meza-Velazquez R et al.:
Association between two polymorphisms of histamine-metabolising enzymes and the severity of allergic rhinitis in a group of Mexican children
Allergol Immunopathol (Madr)
2016
44: 433-438
|
| 18628520 |
Lavery GG et al.:
Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency
J. Clin. Endocrinol. Metab.
2008
93: 3827-3832
|
| 27504266 |
Donti TR et al.:
Diagnosis of adenylosuccinate lyase deficiency by metabolomic profiling in plasma reveals a phenotypic spectrum
Mol Genet Metab Rep
2016
8: 61-66
|
| 25112391 |
Jurecka A et al.:
Adenylosuccinate lyase deficiency
J. Inherit. Metab. Dis.
2015
38: 231-242
|
| 24957512 |
Daignan-Fornier B et al.:
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5-Monophosphate (AICAR), a Highly Conserved Purine Intermediate with Multiple Effects
Metabolites
2012
2: 292-302
|
| 23622405 |
Jinnah HA et al.:
Metabolic disorders of purine metabolism affecting the nervous system
Handb Clin Neurol
2013
113: 1827-1836
|
| 24397858 |
Jeannin G et al.:
Recurrent exercise-induced acute renal failure in a young Pakistani man with severe renal hypouricemia and SLC2A9 compound heterozygosity
BMC Med. Genet.
2014
15: 3
|
| 20516647 |
So A et al.:
Uric acid transport and disease
J. Clin. Invest.
2010
120: 1791-1799
|
| 21256783 |
Stiburkova B et al.:
Novel homozygous insertion in SLC2A9 gene caused renal hypouricemia
Mol. Genet. Metab.
2011
102: 430-435
|
| 22527535 |
Stiburkova B et al.:
Acute kidney injury in two children caused by renal hypouricaemia type 2
Pediatr. Nephrol.
2012
27: 1411-1415
|
| 18327257 |
Vitart V et al.:
SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout
Nat. Genet.
2008
40: 437-442
|
| 18327256 |
Doring A et al.:
SLC2A9 influences uric acid concentrations with pronounced sex-specific effects
Nat. Genet.
2008
40: 430-436
|
| 14739288 |
Augustin R et al.:
Identification and characterization of human glucose transporter-like protein-9 (GLUT9): alternative splicing alters trafficking
J. Biol. Chem.
2004
279
|
| 19926891 |
Dinour D et al.:
Homozygous SLC2A9 mutations cause severe renal hypouricemia
J. Am. Soc. Nephrol.
2010
21: 64-72
|
| 19026395 |
Matsuo H et al.:
Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia
Am. J. Hum. Genet.
2008
83: 744-751
|
| 18701466 |
Anzai N et al.:
Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans
J. Biol. Chem.
2008
283
|
| 21536615 |
Shima Y et al.:
Recurrent EIARF and PRES with severe renal hypouricemia by compound heterozygous SLC2A9 mutation
Pediatrics
2011
127
|
| 19189137 |
Bahat H et al.:
Non-urate transporter 1-related renal hypouricemia and acute renal failure in an Israeli-Arab family
Pediatr. Nephrol.
2009
24: 999-1003
|
| 23043931 |
Li Z et al.:
Novel URAT1 mutations caused acute renal failure after exercise in two Chinese families with renal hypouricemia
Gene
2013
512: 97-101
|
| 26821810 |
Sakiyama M et al.:
The effects of URAT1/SLC22A12 nonfunctional variants, R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression
Sci Rep
2016
6: 20148
|
| 22045201 |
Ochi A et al.:
A case of acute renal failure after exercise with renal hypouricemia demonstrated compound heterozygous mutations of uric acid transporter 1
Clin. Exp. Nephrol.
2012
16: 316-319
|
| 25739858 |
Sugihara S et al.:
Depletion of Uric Acid Due to SLC22A12 (URAT1) Loss-of-Function Mutation Causes Endothelial Dysfunction in Hypouricemia
Circ. J.
2015
79: 1125-1132
|
| 22700886 |
Bollee G et al.:
Adenine phosphoribosyltransferase deficiency
Clin J Am Soc Nephrol
2012
7: 1521-1527
|
| 28466077 |
Jaffer A et al.:
Adenine Phosphoribosyltransferase Deficiency: A Rare Cause of Recurrent Urolithiasis
J Endourol Case Rep
2017
3: 49-51
|
| 28031352 |
Hove-Jensen B et al.:
Phosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology, Utilization, and Metabolic Significance
|
| 22246954 |
Moran R et al.:
Phosphoribosylpyrophosphate synthetase superactivity and recurrent infections is caused by a p.Val142Leu mutation in PRS-I
Am. J. Med. Genet. A
2012
158A: 455-460
|
| 26089585 |
Mittal R et al.:
Association of PRPS1 Mutations with Disease Phenotypes
Dis Markers
2015
2015
|
| 24961627 |
Al-Maawali A et al.:
Prenatal growth restriction, retinal dystrophy, diabetes insipidus and white matter disease: expanding the spectrum of PRPS1-related disorders
Eur. J. Hum. Genet.
2015
23: 310-316
|
| 22035603 |
Brantley MA Jr et al.:
Plasma biomarkers of oxidative stress and genetic variants in age-related macular degeneration
Am. J. Ophthalmol.
2012
153: 460-467.e1
|
| 21882290 |
McKay GJ et al. et al.:
Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies
Hum. Mutat.
2011
32: 1407-1416
|
| 2615605 |
author information missing
[Behavior of plasma and urine purines, after a purine-free diet, in normal subjects and patients with gout]
Medicina (Firenze)
1989
9: 295-297
|
| 28340987 |
Ao GZ et al.:
Discovery of novel curcumin derivatives targeting xanthine oxidase and urate transporter 1 as anti-hyperuricemic agents
Bioorg. Med. Chem.
2017
25: 166-174
|
| 20589576 |
Hosoyamada M et al.:
The effect of testosterone upon the urate reabsorptive transport system in mouse kidney
Nucleosides Nucleotides Nucleic Acids
2010
29: 574-579
|
| 26073243 |
Kurajoh M et al.:
Partial HPRT Deficiency with a Novel Mutation of the HPRT Gene in Combination with Four Previously Reported Variants Associated with Hyperuricemia
Intern. Med.
2015
54: 1523-1526
|
| 25476133 |
Kostalova E et al.:
Hyperuricemia and gout due to deficiency of hypoxanthine-guanine phosphoribosyltransferase in female carriers: New insight to differential diagnosis
Clin. Chim. Acta
2015
440: 214-217
|
| 28566086 |
Dalbeth N et al.:
The genetics of gout: towards personalised medicine?
BMC Med
2017
15: 108
|
| 26909964 |
Ren YC et al.:
PDK2 and ABCG2 genes polymorphisms are correlated with blood glucose levels and uric acid in Tibetan gout patients
|
| 21282933 |
Jutabha P et al.:
Functional analysis of human sodium-phosphate transporter 4 (NPT4/SLC17A3) polymorphisms
J. Pharmacol. Sci.
2011
115: 249-253
|
| 20613716 |
Wright AF et al.:
A complexity of urate transporters
Kidney Int.
2010
78: 446-452
|
| 24318514 |
Sakiyama M et al. et al.:
Common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility
Hum. Cell
2014
27: 1-4
|
| 30115944 |
Mannino GC et al.:
The polymorphism rs35767 at IGF1 locus is associated with serum urate levels
Sci Rep
2018
8: 12255
|
| 15114530 |
Marie S et al.:
AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC
Am. J. Hum. Genet.
2004
74: 1276-1281
|
| 26374178 |
Baggott JE et al.:
Folate-Dependent Purine Nucleotide Biosynthesis in Humans
Adv Nutr
2015
6: 564-571
|
| 29690908 |
Flinn AM et al.:
Adenosine deaminase deficiency: a review
Orphanet J Rare Dis
2018
13: 65
|
| 27579027 |
Whitmore KV et al.:
Adenosine Deaminase Deficiency - More Than Just an Immunodeficiency
Front Immunol
2016
7: 314
|
| 29522447 |
Camici M et al.:
The Inside Story of Adenosine
|
| 28074903 |
Sauer AV et al. et al.:
Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients
Sci Rep
2017
7: 40136
|
| 27086606 |
Gupta M et al.:
Adenosine Deaminase Deficiency with a Novel Gene Mutation
Indian J Pediatr
2016
83: 875-876
|
| 1284479 |
Hirschhorn R et al.:
Identification of two new missense mutations (R156C and S291L) in two ADA- SCID patients unusual for response to therapy with partial exchange transfusions
Hum. Mutat.
1992
1: 166-168
|
| 8227344 |
Santisteban I et al.:
Novel splicing, missense, and deletion mutations in seven adenosine deaminase-deficient patients with late/delayed onset of combined immunodeficiency disease. Contribution of genotype to phenotype
J. Clin. Invest.
1993
92: 2291-2302
|
| 2651461 |
Akeson AL et al.:
Normal and mutant human adenosine deaminase genes
J. Cell. Biochem.
1989
39: 217-228
|
| 27663683 |
Kaljas Y et al.:
Human adenosine deaminases ADA1 and ADA2 bind to different subsets of immune cells
Cell. Mol. Life Sci.
2017
74: 555-570
|
| 1974554 |
Arredondo-Vega FX et al.:
Paradoxical expression of adenosine deaminase in T cells cultured from a patient with adenosine deaminase deficiency and combine immunodeficiency
J. Clin. Invest.
1990
86: 444-452
|
| 3839802 |
et al.:
Identification of a point mutation in the adenosine deaminase gene responsible for immunodeficiency
J. Clin. Invest.
1985
76: 894-897
|
| 2166947 |
Hirschhorn R et al.:
Hot spot mutations in adenosine deaminase deficiency
Proc. Natl. Acad. Sci. U.S.A.
1990
87: 6171-6175
|
| 8614422 |
Bollinger ME et al.:
Brief report: hepatic dysfunction as a complication of adenosine deaminase deficiency
N. Engl. J. Med.
1996
334: 1367-1371
|
| 9225964 |
Hirschhorn R et al.:
Two newly identified mutations (Thr233Ile and Leu152Met) in partially adenosine deaminase-deficient (ADA-) individuals that result in differing biochemical and metabolic phenotypes
Hum. Genet.
1997
100: 22-29
|
| 20453107 |
Zavialov AV et al.:
Human adenosine deaminase 2 induces differentiation of monocytes into macrophages and stimulates proliferation of T helper cells and macrophages
J. Leukoc. Biol.
2010
88: 279-290
|
| 29375373 |
Fumagalli M et al.:
Pathophysiological Role of Purines and Pyrimidines in Neurodevelopment: Unveiling New Pharmacological Approaches to Congenital Brain Diseases
Front Pharmacol
2017
8: 941
|
| 28842866 |
Bradford KL et al.:
Adenosine Deaminase (ADA)-Deficient Severe Combined Immune Deficiency (SCID): Molecular Pathogenesis and Clinical Manifestations
J. Clin. Immunol.
2017
37: 626-637
|
| 24113229 |
Grunebaum E et al.:
Recent advances in understanding and managing adenosine deaminase and purine nucleoside phosphorylase deficiencies
Curr Opin Allergy Clin Immunol
2013
13: 630-638
|
| 20959412 |
Martinez-Navio JM et al.:
Adenosine deaminase potentiates the generation of effector, memory, and regulatory CD4+ T cells
J. Leukoc. Biol.
2011
89: 127-136
|
| 29497379 |
Moreno E et al.:
Molecular Evidence of Adenosine Deaminase Linking Adenosine A2A Receptor and CD26 Proteins
Front Pharmacol
2018
9: 106
|
| 21306300 |
Gracia E et al.:
A2A adenosine receptor ligand binding and signalling is allosterically modulated by adenosine deaminase
Biochem. J.
2011
435: 701-709
|
| 8099155 |
author information missing
Adult presentation of adenosine deaminase deficiency
Lancet
1993
341: 1471
|
| 11435465 |
Apasov SG et al.:
Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling
J. Clin. Invest.
2001
108: 131-141
|
| 29744787 |
Cagdas D et al. et al.:
ADA Deficiency: Evaluation of the Clinical and Laboratory Features and the Outcome
|
| 16176880 |
Nyhan WL et al.:
Disorders of purine and pyrimidine metabolism
Mol. Genet. Metab.
2005
86: 25-33
|
| 22969765 |
Sauer AV et al.:
Autoimmune dysregulation and purine metabolism in adenosine deaminase deficiency
Front Immunol
2012
3: 265
|
| 10996775 |
Abe M et al.:
Myoadenylate deaminase deficiency with progressive muscle weakness and atrophy caused by new missense mutations in AMPD1 gene: case report in a Japanese patient
Neuromuscul. Disord.
2000
10: 472-477
|
| 1631143 |
Morisaki T et al.:
Molecular basis of AMP deaminase deficiency in skeletal muscle
Proc. Natl. Acad. Sci. U.S.A.
1992
89: 6457-6461
|
| 27896074 |
Cheng J et al. et al.:
Effect of isolated AMP deaminase deficiency on skeletal muscle function
Mol Genet Metab Rep
2014
1: 51-59
|
| 21686757 |
Lucia A et al.:
C34T mutation of the AMPD1 gene in an elite white runner
|
| 27323204 |
Nemati R et al.:
Association between the C34T polymorphism of the AMPD1 gene and essential hypertension in Malaysian patients
|
| 26439223 |
author information missing
Possible influence of AMPD1 on cholinergic neurotransmission and sleep
J Sleep Res
2016
25: 124-126
|
| 24885427 |
Gineviciene V et al.:
AMPD1 rs17602729 is associated with physical performance of sprint and power in elite Lithuanian athletes
BMC Genet.
2014
15: 58
|
| 15677729 |
Rubio JC et al.:
Frequency of the C34T mutation of the AMPD1 gene in world-class endurance athletes: does this mutation impair performance?
J. Appl. Physiol.
2005
98: 2108-2112
|
| 23911318 |
Akizu N et al. et al.:
AMPD2 regulates GTP synthesis and is mutated in a potentially treatable neurodegenerative brainstem disorder
Cell
2013
154: 505-517
|
| 27066553 |
Marsh AP et al. et al.:
Complete callosal agenesis, pontocerebellar hypoplasia, and axonal neuropathy due to AMPD2 loss
Neurol Genet
2015
1: e16
|
| 29463858 |
Kortum F et al. et al.:
Clinical and genetic spectrum of AMPD2-related pontocerebellar hypoplasia type 9
Eur. J. Hum. Genet.
2018
26: 695-708
|
| 28815207 |
Accogli A et al. et al.:
Novel AMPD2 mutation in pontocerebellar hypoplasia, dysmorphisms, and teeth abnormalities
Neurol Genet
2017
3: e179
|
| 8526848 |
Van den Bergh F et al.:
Characterization of human AMP deaminase 2 (AMPD2) gene expression reveals alternative transcripts encoding variable N-terminal extensions of isoform L
Biochem. J.
1995
312: ( Pt 2) 401-410
|
| 29903031 |
van Dijk T et al.:
Whats new in pontocerebellar hypoplasia? An update on genes and subtypes
Orphanet J Rare Dis
2018
13: 92
|
| 24482476 |
Novarino G et al. et al.:
Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders
Science
2014
343: 506-511
|
| 1384322 |
Aust MR et al.:
Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency
Am. J. Hum. Genet.
1992
51: 763-772
|
| 23371835 |
Somech R et al.:
Purine nucleoside phosphorylase deficiency presenting as severe combined immune deficiency
Immunol. Res.
2013
56: 150-154
|
| 3029074 |
et al.:
A human purine nucleoside phosphorylase deficiency caused by a single base change
J. Biol. Chem.
1987
262: 2332-2338
|
| 8931706 |
Pannicke U et al.:
Two novel missense and frameshift mutations in exons 5 and 6 of the purine nucleoside phosphorylase (PNP) gene in a severe combined immunodeficiency (SCID) patient
Hum. Genet.
1996
98: 706-709
|
| 11453975 |
Dalal I et al.:
Two novel mutations in a purine nucleoside phosphorylase (PNP)-deficient patient
Clin. Genet.
2001
59: 430-437
|
| 24767876 |
la Marca G et al. et al.:
Diagnosis of immunodeficiency caused by a purine nucleoside phosphorylase defect by using tandem mass spectrometry on dried blood spots
J. Allergy Clin. Immunol.
2014
134: 155-159
|
| 22602837 |
Nobre S et al.:
Neonatal liver failure due to deoxyguanosine kinase deficiency
|
| 22137549 |
Mudd SH et al.:
Two patients with hepatic mtDNA depletion syndromes and marked elevations of S-adenosylmethionine and methionine
Mol. Genet. Metab.
2012
105: 228-236
|
| 21107780 |
Pronicka E et al. et al.:
Post mortem identification of deoxyguanosine kinase (DGUOK) gene mutations combined with impaired glucose homeostasis and iron overload features in four infants with severe progressive liver failure
J. Appl. Genet.
2011
52: 61-66
|
| 8706825 |
Wang L et al.:
Cloning and expression of human mitochondrial deoxyguanosine kinase cDNA
FEBS Lett.
1996
390: 39-43
|
| 15887277 |
Tadiboyina VT et al.:
Novel mutation in DGUOK in hepatocerebral mitochondrial DNA depletion syndrome associated with cystathioninuria
Am. J. Med. Genet. A
2005
135: 289-291
|
| 7494863 |
Arner ES et al.:
Mammalian deoxyribonucleoside kinases
Pharmacol. Ther.
1995
67: 155-186
|
| 18205204 |
Dimmock DP et al. et al.:
Clinical and molecular features of mitochondrial DNA depletion due to mutations in deoxyguanosine kinase
Hum. Mutat.
2008
29: 330-331
|
| 21478040 |
Hanchard NA et al.:
Deoxyguanosine kinase deficiency presenting as neonatal hemochromatosis
Mol. Genet. Metab.
2011
103: 262-267
|
| 19394258 |
Brahimi N et al.:
The first founder DGUOK mutation associated with hepatocerebral mitochondrial DNA depletion syndrome
Mol. Genet. Metab.
2009
97: 221-226
|
| 15639197 |
Wang L et al.:
Molecular insight into mitochondrial DNA depletion syndrome in two patients with novel mutations in the deoxyguanosine kinase and thymidine kinase 2 genes
Mol. Genet. Metab.
2005
84: 75-82
|
| 27965370 |
Perez-Rivas LG et al.:
Genetic characterization of a mouse line with primary aldosteronism
J. Mol. Endocrinol.
2017
58: 67-78
|
| 26874653 |
Vilarinho S et al.:
Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension
Hepatology
2016
63: 1977-1986
|
| 23043144 |
Ronchi D et al. et al.:
Next-generation sequencing reveals DGUOK mutations in adult patients with mitochondrial DNA multiple deletions
Brain
2012
135: 3404-3415
|
| 24552284 |
Zhou Q et al. et al.:
Early-onset stroke and vasculopathy associated with mutations in ADA2
N. Engl. J. Med.
2014
370: 911-920
|
| 24552285 |
Navon Elkan P et al. et al.:
Mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy
N. Engl. J. Med.
2014
370: 921-931
|
| 29951947 |
Meyts I et al.:
Deficiency of Adenosine Deaminase 2 (DADA2): Updates on the Phenotype, Genetics, Pathogenesis, and Treatment
J. Clin. Immunol.
2018
38: 569-578
|
| 26867732 |
Van Montfrans JM et al. et al.:
Phenotypic variability in patients with ADA2 deficiency due to identical homozygous R169Q mutations
Rheumatology (Oxford)
2016
55: 902-910
|
| 25278816 |
Belot A et al. et al.:
Mutations in CECR1 associated with a neutrophil signature in peripheral blood
Pediatr Rheumatol Online J
2014
12: 44
|
| 26131734 |
Gonzalez Santiago TM et al.:
Dermatologic Features of ADA2 Deficiency in Cutaneous Polyarteritis Nodosa
JAMA Dermatol
2015
151: 1230-1234
|
| 29600946 |
Lamprecht P et al.:
Diagnosis of deficiency of adenosine deaminase 2 with early onset polyarteritis nodosa in an adult patient with a novel compound heterozygous CECR1 mutation
Clin. Exp. Rheumatol.
2018
36: Suppl 111 177
|
| 28024309 |
Elbracht M et al.:
Stroke as Initial Manifestation of Adenosine Deaminase 2 Deficiency
Neuropediatrics
2017
48: 111-114
|
| 27069017 |
Keer N et al.:
Novel compound heterozygous variants in CECR1 gene associated with childhood onset polyarteritis nodosa and deficiency of ADA2
Rheumatology (Oxford)
2016
55: 1145-1147
|
| 28830446 |
Skrabl-Baumgartner A et al.:
Autoimmune phenotype with type I interferon signature in two brothers with ADA2 deficiency carrying a novel CECR1 mutation
Pediatr Rheumatol Online J
2017
15: 67
|
| 28522451 |
Caorsi R et al. et al.:
ADA2 deficiency (DADA2) as an unrecognised cause of early onset polyarteritis nodosa and stroke: a multicentre national study
Ann. Rheum. Dis.
2017
76: 1648-1656
|
| 27059682 |
Nanthapisal S et al. et al.:
Deficiency of Adenosine Deaminase Type 2: A Description of Phenotype and Genotype in Fifteen Cases
|
| 25551694 |
Wu S et al.:
Sneddons syndrome: a comprehensive review of the literature
Orphanet J Rare Dis
2014
9: 215
|
| 29988314 |
Fabiani G et al.:
Cognitive and psychiatric changes as first clinical presentation in Sneddon syndrome
Dement Neuropsychol
2018
12: 216-219
|
| 15255506 |
Bolayir E et al.:
Sneddons syndrome: clinical and laboratory analysis of 10 cases
Acta Med. Okayama
2004
58: 59-65
|
| 8466214 |
Zelger B et al.:
Sneddons syndrome. A long-term follow-up of 21 patients
Arch Dermatol
1993
129: 437-447
|
| 15024124 |
Baric I et al. et al.:
S-adenosylhomocysteine hydrolase deficiency in a human: a genetic disorder of methionine metabolism
Proc. Natl. Acad. Sci. U.S.A.
2004
101: 4234-4239
|
| 26527160 |
Stender S et al.:
Adult-onset liver disease and hepatocellular carcinoma in S-adenosylhomocysteine hydrolase deficiency
Mol. Genet. Metab.
2015
116: 269-274
|
| 20852937 |
Grubbs R et al.:
S-adenosylhomocysteine hydrolase deficiency: two siblings with fetal hydrops and fatal outcomes
J. Inherit. Metab. Dis.
2010
33: 705-713
|
| 16736098 |
Buist NR et al.:
S-adenosylhomocysteine hydrolase deficiency in a 26-year-old man
J. Inherit. Metab. Dis.
2006
29: 538-545
|
| 16435181 |
Baric I et al. et al.:
S-Adenosylhomocysteine hydrolase deficiency: a second patient, the younger brother of the index patient, and outcomes during therapy
J. Inherit. Metab. Dis.
2005
28: 885-902
|
| 10233365 |
Bianchi P et al.:
A case of complete adenylate kinase deficiency due to a nonsense mutation in AK-1 gene (Arg 107 --> Stop, CGA --> TGA) associated with chronic haemolytic anaemia
Br. J. Haematol.
1999
105: 75-79
|
| 19468337 |
Dzeja P et al.:
Adenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensing
Int J Mol Sci
2009
10: 1729-1772
|
| 21963049 |
Bjursell MK et al. et al.:
Adenosine kinase deficiency disrupts the methionine cycle and causes hypermethioninemia, encephalopathy, and abnormal liver function
Am. J. Hum. Genet.
2011
89: 507-515
|
| 26642971 |
Staufner C et al. et al.:
Adenosine kinase deficiency: expanding the clinical spectrum and evaluating therapeutic options
J. Inherit. Metab. Dis.
2016
39: 273-283
|
| 27903722 |
Sandau US et al. et al.:
Adenosine Kinase Deficiency in the Brain Results in Maladaptive Synaptic Plasticity
J. Neurosci.
2016
36
|
| 27500280 |
Shakiba M et al.:
Adenosine kinase deficiency with neurodevelopemental delay and recurrent hepatic dysfunction: A case report
|
| 10657589 |
Zoref-Shani E et al.:
Kelley-Seegmiller syndrome due to a unique variant of hypoxanthine-guanine phosphoribosyltransferase: reduced affinity for 5-phosphoribosyl-1-pyrophosphate manifested only at low, physiological substrate concentrations
Biochim. Biophys. Acta
2000
1500: 197-203
|
| 18067674 |
Torres RJ et al.:
Hypoxanthine-guanine phosophoribosyltransferase (HPRT) deficiency: Lesch-Nyhan syndrome
Orphanet J Rare Dis
2007
2: 48
|
| 23203137 |
Ichida K et al.:
Mutations associated with functional disorder of xanthine oxidoreductase and hereditary xanthinuria in humans
Int J Mol Sci
2012
13
|
| 16280366 |
McColl SR et al.:
Immunomodulatory impact of the A2A adenosine receptor on the profile of chemokines produced by neutrophils
FASEB J.
2006
20: 187-189
|
| 25075845 |
et al.:
Mutant ADA2 in vasculopathies
N. Engl. J. Med.
2014
371: 478
|
| 28516235 |
Sahin S et al.:
Clinical, imaging and genotypical features of three deceased and five surviving cases with ADA2 deficiency
Rheumatol. Int.
2018
38: 129-136
|
| 26922074 |
Schepp J et al.:
Deficiency of Adenosine Deaminase 2 Causes Antibody Deficiency
J. Clin. Immunol.
2016
36: 179-186
|
| 29681619 |
Rama M et al. et al.:
A decision tree for the genetic diagnosis of deficiency of adenosine deaminase 2 (DADA2): a French reference centres experience
Eur. J. Hum. Genet.
2018
26: 960-971
|
| 29564582 |
Cipe FE et al.:
Novel Mutation in CECR1 Leads to Deficiency of ADA2 with Associated Neutropenia
J. Clin. Immunol.
2018
38: 273-277
|
| 28230570 |
Hashem H et al.:
Refractory Pure Red Cell Aplasia Manifesting as Deficiency of Adenosine Deaminase 2
J. Pediatr. Hematol. Oncol.
2017
39: e293-e296
|
| 26914925 |
Poswar Fde O et al.:
Adenosine deaminase 2 deficiency presenting as spastic paraplegia and systemic vasculitis
J. Neurol.
2016
263: 818-820
|
| 27252897 |
Uettwiller F et al.:
ADA2 deficiency: case report of a new phenotype and novel mutation in two sisters
RMD Open
2016
2
|
| 28493328 |
Schepp J et al. et al.:
Screening of 181 Patients With Antibody Deficiency for Deficiency of Adenosine Deaminase 2 Sheds New Light on the Disease in Adulthood
|
| 26233953 |
Batu ED et al.:
A Case Series of Adenosine Deaminase 2-deficient Patients Emphasizing Treatment and Genotype-phenotype Correlations
J. Rheumatol.
2015
42: 1532-1534
|
| 25888558 |
Westendorp WF et al.:
Unexplained early-onset lacunar stroke and inflammatory skin lesions: Consider ADA2 deficiency
Neurology
2015
84: 2092-2093
|
| 15926889 |
Zavialov AV et al.:
Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity
Biochem. J.
2005
391: 51-57
|
| 21288095 |
St Hilaire C et al. et al.:
NT5E mutations and arterial calcifications
N. Engl. J. Med.
2011
364: 432-442
|
| 23040839 |
Hofmann Bowman MA et al.:
Genetic pathways of vascular calcification
Trends Cardiovasc. Med.
2012
22: 93-98
|
| 23296303 |
Colgan SP et al.:
Adenosine and gastrointestinal inflammation
J. Mol. Med.
2013
91: 157-164
|
| 25960051 |
Bjelobaba I et al.:
Purinergic signaling pathways in endocrine system
Auton Neurosci
2015
191: 102-116
|
| 12881724 |
Rutsch F et al. et al.:
Mutations in ENPP1 are associated with idiopathic infantile arterial calcification
Nat. Genet.
2003
34: 379-381
|
| 29976176 |
Brunod I et al.:
Generalized arterial calcification of infancy with a novel ENPP1 mutation: a case report
BMC Pediatr
2018
18: 217
|
| 23430823 |
Galletti S et al.:
Generalized Arterial Calcification of Infancy: Fatal Clinical Course Associated with a Novel Mutation in ENPP1
JIMD Rep
2011
1: 23-27
|
| 21151691 |
Guimaraes S et al.:
Idiopathic infantile arterial calcification: a rare cause of sudden unexpected death in childhood
Patholog Res Int
2010
2010
|
| 22629037 |
Kalal IG et al.:
Molecular diagnosis of generalized arterial calcification of infancy (GACI)
J Cardiovasc Dis Res
2012
3: 150-154
|
| 24717293 |
Lomashvili KA et al.:
Vascular calcification is dependent on plasma levels of pyrophosphate
Kidney Int.
2014
85: 1351-1356
|
| 20137773 |
Lorenz-Depiereux B et al.:
Loss-of-function ENPP1 mutations cause both generalized arterial calcification of infancy and autosomal-recessive hypophosphatemic rickets
Am. J. Hum. Genet.
2010
86: 267-272
|
| 20015201 |
Nitschke Y et al.:
Expression of NPP1 is regulated during atheromatous plaque calcification
J. Cell. Mol. Med.
2011
15: 220-231
|
| 20016754 |
Rutsch F et al. et al.:
Hypophosphatemia, hyperphosphaturia, and bisphosphonate treatment are associated with survival beyond infancy in generalized arterial calcification of infancy
Circ Cardiovasc Genet
2008
1: 133-140
|
| 19452427 |
Sawyer T et al.:
Generalized arterial calcification of infancy associated with meconium peritonitis: a case report and review of the literature
Am J Perinatol
2009
26: 711-716
|
| 24530784 |
Serrano RL et al.:
Mono-allelic and bi-allelic ENPP1 deficiency promote post-injury neointimal hyperplasia associated with increased C/EBP homologous protein expression
Atherosclerosis
2014
233: 493-502
|
| 29244957 |
Thumbigere-Math V et al. et al.:
Hypercementosis Associated with ENPP1 Mutations and GACI
J. Dent. Res.
2018
97: 432-441
|
| 15940697 |
Cheng KS et al.:
Generalized arterial calcification of infancy: different clinical courses in two affected siblings
Am. J. Med. Genet. A
2005
136: 210-213
|
| 21490328 |
Villa-Bellosta R et al.:
Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle
Am. J. Physiol. Heart Circ. Physiol.
2011
301: H61-H68
|
| 15605415 |
Ruf N et al.:
The mutational spectrum of ENPP1 as arising after the analysis of 23 unrelated patients with generalized arterial calcification of infancy (GACI)
Hum. Mutat.
2005
25: 98
|
| 16369898 |
Numakura C et al.:
Genetic and enzymatic analysis for two Japanese patients with idiopathic infantile arterial calcification
J. Bone Miner. Metab.
2006
24: 48-52
|
| 12757929 |
Goding JW et al.:
Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family
Biochim. Biophys. Acta
2003
1638: 1-19
|
| 30111653 |
Jin Y et al.:
Enpp1 inhibits ectopic joint calcification and maintains articular chondrocytes by repressing hedgehog signaling
|
| 16315058 |
Ciana G et al.:
Generalized arterial calcification of infancy: two siblings with prolonged survival
Eur. J. Pediatr.
2006
165: 258-263
|
| 27406238 |
Palazzo L et al.:
ENPP1 processes protein ADP-ribosylation in vitro
FEBS J.
2016
283: 3371-3388
|
| 18655772 |
Huang MS et al.:
Phosphate and pyrophosphate mediate PKA-induced vascular cell calcification
Biochem. Biophys. Res. Commun.
2008
374: 553-558
|
| 24604335 |
Mackenzie NC et al.:
miRNA-221 and miRNA-222 synergistically function to promote vascular calcification
Cell Biochem. Funct.
2014
32: 209-216
|
| 28052917 |
Ahmed MY et al.:
A mutation of EPT1 (SELENOI) underlies a new disorder of Kennedy pathway phospholipid biosynthesis
Brain
2017
140: 547-554
|
| 29123918 |
Darvish H et al.:
Whole genome sequencing identifies a novel homozygous exon deletion in the NT5C2 gene in a family with intellectual disability and spastic paraplegia
|
| 28327087 |
Elsaid MF et al.:
NT5C2 novel splicing variant expands the phenotypic spectrum of Spastic Paraplegia (SPG45): case report of a new member of thin corpus callosum SPG-Subgroup
BMC Med. Genet.
2017
18: 33
|
| 24216977 |
Brachet C et al.:
Hearing loss is part of the clinical picture of ENPP1 loss of function mutation
Horm Res Paediatr
2014
81: 63-66
|
| 20137772 |
Levy-Litan V et al.:
Autosomal-recessive hypophosphatemic rickets is associated with an inactivation mutation in the ENPP1 gene
Am. J. Hum. Genet.
2010
86: 273-278
|
| 30911583 |
Lamquet S et al.:
A likely pathogenic variant in the SLC20A2 gene presenting with progressive myoclonus
Ann Clin Transl Neurol
2019
6: 605-609
|
| 17710231 |
author information missing
article information missing
|
| 25860694 |
author information missing
article information missing
|
| 24075184 |
Eytan O et al. et al.:
Cole Disease Results from Mutations in ENPP1
Am. J. Hum. Genet.
2013
93: 752-757
|
| 26617416 |
Schlipf NA et al.:
Association of Cole disease with novel heterozygous mutations in the somatomedin-B domains of the ENPP1 gene: necessary, but not always sufficient
Br. J. Dermatol.
2016
174: 1152-1156
|
| 28964717 |
Chourabi M et al. et al.:
ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis
J. Invest. Dermatol.
2018
138: 291-300
|
| 30652007 |
Mamelona J et al.:
A new case of spastic paraplegia type 64 due to a missense mutation in the ENTPD1 gene
Hum Genome Var
2019
6: 5
|
| 24211385 |
Faletra F et al.:
A novel P2RX2 mutation in an Italian family affected by autosomal dominant nonsyndromic hearing loss
Gene
2014
534: 236-239
|
| 23345450 |
Yan D et al. et al.:
Mutation of the ATP-gated P2X(2) receptor leads to progressive hearing loss and increased susceptibility to noise
Proc. Natl. Acad. Sci. U.S.A.
2013
110: 2228-2233
|
| 27252659 |
Mittal R et al.:
Characterization of ATPase Activity of P2RX2 Cation Channel
Front Physiol
2016
7: 186
|
| 1333302 |
Cattaneo M et al.:
Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate
Blood
1992
80: 2787-2796
|
| 12578987 |
Cattaneo M et al.:
Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding
Proc. Natl. Acad. Sci. U.S.A.
2003
100: 1978-1983
|
| 20966167 |
Cattaneo M et al.:
The platelet P2Y(1)(2) receptor for adenosine diphosphate: congenital and drug-induced defects
Blood
2011
117: 2102-2112
|
| 11196645 |
Hollopeter G et al.:
Identification of the platelet ADP receptor targeted by antithrombotic drugs
Nature
2001
409: 202-207
|
| 27487748 |
Lecchi A et al.:
Inherited dysfunctional platelet P2Y12 receptor mutations associated with bleeding disorders
Hamostaseologie
2016
36: 279-283
|
| 25428217 |
Lecchi A et al.:
Identification of a new dysfunctional platelet P2Y12 receptor variant associated with bleeding diathesis
Blood
2015
125: 1006-1013
|
| 22628078 |
Hogberg C et al.:
Farnesyl pyrophosphate is an endogenous antagonist to ADP-stimulated P2Y(1)(2) receptor-mediated platelet aggregation
Thromb. Haemost.
2012
108: 119-132
|
| 28824625 |
Rader BA et al.:
Alkaline Phosphatase, an Unconventional Immune Protein
Front Immunol
2017
8: 897
|
| 27084188 |
Linglart A et al.:
Hypophosphatasia
Curr Osteoporos Rep
2016
14: 95-105
|
| 27274262 |
Orimo H et al.:
Pathophysiology of hypophosphatasia and the potential role of asfotase alfa
Ther Clin Risk Manag
2016
12: 777-786
|
| 4031070 |
et al.:
Markedly increased circulating pyridoxal-5-phosphate levels in hypophosphatasia. Alkaline phosphatase acts in vitamin B6 metabolism
J. Clin. Invest.
1985
76: 752-756
|
| 11438998 |
Taillandier A et al. et al.:
Twelve novel mutations in the tissue-nonspecific alkaline phosphatase gene (ALPL) in patients with various forms of hypophosphatasia
Hum. Mutat.
2001
18: 83-84
|
| 24123110 |
Guanabens N et al.:
Calcific periarthritis as the only clinical manifestation of hypophosphatasia in middle-aged sisters
J. Bone Miner. Res.
2014
29: 929-934
|
| 26432670 |
Taillandier A et al. et al.:
Molecular diagnosis of hypophosphatasia and differential diagnosis by targeted Next Generation Sequencing
Mol. Genet. Metab.
2015
116: 215-220
|
| 18769927 |
Collmann H et al.:
Neurosurgical aspects of childhood hypophosphatasia
Childs Nerv Syst
2009
25: 217-223
|
| 19232125 |
Reibel A et al.:
Orodental phenotype and genotype findings in all subtypes of hypophosphatasia
Orphanet J Rare Dis
2009
4: 6
|
| 24569605 |
Hofmann C et al.:
Unexpected high intrafamilial phenotypic variability observed in hypophosphatasia
Eur. J. Hum. Genet.
2014
22: 1160-1164
|
| 24276437 |
Taketani T et al.:
Clinical and genetic aspects of hypophosphatasia in Japanese patients
Arch. Dis. Child.
2014
99: 211-215
|
| 25731960 |
Whyte MP et al.:
Hypophosphatasia: validation and expansion of the clinical nosology for children from 25 years experience with 173 pediatric patients
Bone
2015
75: 229-239
|
| 30508915 |
Castells L et al.:
Neonatal lethal hypophosphatasia: A case report and review of literature
Medicine (Baltimore)
2018
97
|
| 1409720 |
Henthorn PS et al.:
Different missense mutations at the tissue-nonspecific alkaline phosphatase gene locus in autosomal recessively inherited forms of mild and severe hypophosphatasia
Proc. Natl. Acad. Sci. U.S.A.
1992
89: 9924-9928
|
| 3350970 |
Whyte MP et al.:
Perinatal hypophosphatasia: tissue levels of vitamin B6 are unremarkable despite markedly increased circulating concentrations of pyridoxal-5-phosphate. Evidence for an ectoenzyme role for tissue-nonspecific alkaline phosphatase
J. Clin. Invest.
1988
81: 1234-1239
|
| 3174660 |
Weiss MJ et al.:
A missense mutation in the human liver/bone/kidney alkaline phosphatase gene causing a lethal form of hypophosphatasia
Proc. Natl. Acad. Sci. U.S.A.
1988
85: 7666-7669
|
| 21713987 |
Wenkert D et al.:
Hypophosphatasia: nonlethal disease despite skeletal presentation in utero (17 new cases and literature review)
J. Bone Miner. Res.
2011
26: 2389-2398
|
| 21596366 |
Miskinyte S et al. et al.:
Loss of BRCC3 deubiquitinating enzyme leads to abnormal angiogenesis and is associated with syndromic moyamoya
Am. J. Hum. Genet.
2011
88: 718-728
|
| 29907875 |
Hori I et al. et al.:
A novel homozygous missense mutation in the SH3-binding motif of STAMBP causing microcephaly-capillary malformation syndrome
J. Hum. Genet.
2018
63: 957-963
|
| 28492230 |
Bednash JS et al.:
Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity
Nat Commun
2017
8: 15203
|
| 25692795 |
Faqeih EA et al.:
Novel STAMBP mutation and additional findings in an Arabic family
Am. J. Med. Genet. A
2015
167A: 805-809
|
| 24151880 |
Davies CW et al.:
Mechanism of recruitment and activation of the endosome-associated deubiquitinase AMSH
Biochemistry
2013
52: 7818-7829
|
| 16854379 |
Herrera-Vigenor F et al.:
AMSH regulates calcium-sensing receptor signaling through direct interactions
Biochem. Biophys. Res. Commun.
2006
347: 924-930
|
| 15314065 |
McCullough J et al.:
AMSH is an endosome-associated ubiquitin isopeptidase
J. Cell Biol.
2004
166: 487-492
|
| 23542699 |
McDonell LM et al. et al.:
Mutations in STAMBP, encoding a deubiquitinating enzyme, cause microcephaly-capillary malformation syndrome
Nat. Genet.
2013
45: 556-562
|
| 21271646 |
Carter MT et al.:
A new syndrome with multiple capillary malformations, intractable seizures, and brain and limb anomalies
Am. J. Med. Genet. A
2011
155A: 301-306
|
| 17426287 |
Reyes-Ibarra AP et al.:
Calcium-sensing receptor endocytosis links extracellular calcium signaling to parathyroid hormone-related peptide secretion via a Rab11a-dependent and AMSH-sensitive mechanism
Mol. Endocrinol.
2007
21: 1394-1407
|
| 11483516 |
Itoh F et al.:
Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads
EMBO J.
2001
20: 4132-4142
|
| 25266620 |
Pavlovic M et al.:
The microcephaly-capillary malformation syndrome in two brothers with novel clinical features
Pediatr. Neurol.
2014
51: 560-565
|
| 30873819 |
Heinzmann D et al.:
Mitochondrial Dynamics in Tachycardiomyopathy
Cell. Physiol. Biochem.
2019
52: 435-438
|
| 21511967 |
author information missing
Compound heterozygosity for 2 novel TMEM16F mutations in a patient with Scott syndrome
Blood
2011
117: 4399-4400
|
| 30586926 |
Brigant B et al.:
TRIMming down to TRIM37: Relevance to Inflammation, Cardiovascular Disorders, and Cancer in MULIBREY Nanism
|
| 15885686 |
Kallijarvi J et al.:
TRIM37 defective in mulibrey nanism is a novel RING finger ubiquitin E3 ligase
Exp. Cell Res.
2005
308: 146-155
|
| 17100991 |
Hamalainen RH et al.:
Wilms tumor and novel TRIM37 mutations in an Australian patient with mulibrey nanism
Clin. Genet.
2006
70: 473-479
|
| 14757854 |
Karlberg N et al.:
Mulibrey nanism: clinical features and diagnostic criteria
J. Med. Genet.
2004
41: 92-98
|
| 28724525 |
Wang W et al.:
TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import
J. Cell Biol.
2017
216: 2843-2858
|
| 29477054 |
Dai Y et al.:
TRIM37 inhibits PDGF-BB-induced proliferation and migration of airway smooth muscle cells
Biomed. Pharmacother.
2018
101: 24-29
|
| 29324313 |
Tang SL et al.:
Knockdown of TRIM37 suppresses the proliferation, migration and invasion of glioma cells through the inactivation of PI3K/Akt signaling pathway
Biomed. Pharmacother.
2018
99: 59-64
|
| 28815877 |
Jobic F et al.:
New intragenic rearrangements in non-Finnish mulibrey nanism
Am. J. Med. Genet. A
2017
173: 2782-2788
|
| 25470042 |
Bhatnagar S et al.:
TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein
Nature
2014
516: 116-120
|
| 23769972 |
Balestra FR et al.:
Discovering regulators of centriole biogenesis through siRNA-based functional genomics in human cells
Dev. Cell
2013
25: 555-571
|
| 15108285 |
Hamalainen RH et al.:
Novel mutations in the TRIM37 gene in Mulibrey Nanism
Hum. Mutat.
2004
23: 522
|
| 28496510 |
Davarpasand T et al.:
Constrictive Pericarditis and Primary Amenorrhea with Syndactyly in an Iranian Female: Mulibrey Nanism Syndrome
J Tehran Heart Cent
2016
11: 187-191
|
| 12754710 |
Jagiello P et al.:
A novel splice site mutation in the TRIM37 gene causes mulibrey nanism in a Turkish family with phenotypic heterogeneity
Hum. Mutat.
2003
21: 630-635
|
| 23385855 |
Kumpf M et al.:
Refractory congestive heart failure following delayed pericardectomy in a 12-year-old child with Mulibrey nanism due to a novel mutation in TRIM37
Eur. J. Pediatr.
2013
172: 1415-1418
|
| 11938494 |
Kallijarvi J et al.:
The TRIM37 gene encodes a peroxisomal RING-B-box-coiled-coil protein: classification of mulibrey nanism as a new peroxisomal disorder
Am. J. Hum. Genet.
2002
70: 1215-1228
|
| 25003005 |
Tuzovic L et al.:
A human de novo mutation in MYH10 phenocopies the loss of function mutation in mice
Rare Dis
2013
1
|
| 12471201 |
Vervoort VS et al.:
Sorting nexin 3 (SNX3) is disrupted in a patient with a translocation t(6;13)(q21;q12) and microcephaly, microphthalmia, ectrodactyly, prognathism (MMEP) phenotype
J. Med. Genet.
2002
39: 893-899
|
| 24748105 |
Mirzaa GM et al.:
Mutations in CENPE define a novel kinetochore-centromeric mechanism for microcephalic primordial dwarfism
Hum Genet
2014
133: 1023-1039
|
| 24449199 |
Arzoo PS et al.:
WNT10A mutations account for (1/4) of population-based isolated oligodontia and show phenotypic correlations
Am. J. Med. Genet. A
2014
164A: 353-359
|
| 19559398 |
Bohring A et al.:
WNT10A mutations are a frequent cause of a broad spectrum of ectodermal dysplasias with sex-biased manifestation pattern in heterozygotes
Am. J. Hum. Genet.
2009
85: 97-105
|
| 26942284 |
Lesage S et al. et al.:
Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy
Am. J. Hum. Genet.
2016
98: 500-513
|
| 34295884 |
author information missing
article information missing
|
| 22095910 |
Slavotinek AM et al.:
VAX1 mutation associated with microphthalmia, corpus callosum agenesis, and orofacial clefting: the first description of a VAX1 phenotype in humans
Hum. Mutat.
2012
33: 364-368
|
| 19854269 |
Zhao L et al.:
Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain
Mech. Dev.
2010
127: 62-72
|
| 26428751 |
Watson CM et al.:
Identification of a mutation in the ubiquitin-fold modifier 1-specific peptidase 2 gene, UFSP2, in an extended South African family with Beukes hip dysplasia
S. Afr. Med. J.
2015
105: 558-563
|
| 28892125 |
Di Rocco M et al.:
Novel spondyloepimetaphyseal dysplasia due to UFSP2 gene mutation
Clin. Genet.
2018
93: 671-674
|
| 6432893 |
author information missing
Hypothalamic hypothyroidism due to isolated thyrotropin-releasing hormone (TRH) deficiency
J. Endocrinol. Invest.
1984
7: 231-233
|
| 30267750 |
Peres Diaz LS et al.:
Angiotensin II requires an intact cardiac thyrotropin-releasing hormone (TRH) system to induce cardiac hypertrophy in mouse
J. Mol. Cell. Cardiol.
2018
124: 1-11
|
| 27773428 |
Jerber J et al. et al.:
Biallelic Mutations in TMTC3, Encoding a Transmembrane and TPR-Containing Protein, Lead to Cobblestone Lissencephaly
Am. J. Hum. Genet.
2016
99: 1181-1189
|
| 21603654 |
Racape M et al. et al.:
The involvement of SMILE/TMTC3 in endoplasmic reticulum stress response
PLoS ONE
2011
6
|
| 28973932 |
Larsen ISB et al. et al.:
Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins
Proc. Natl. Acad. Sci. U.S.A.
2017
114
|
| 21956870 |
Yun EJ et al.:
mSmile is necessary for bronchial smooth muscle and alveolar myofibroblast development
Anat Rec (Hoboken)
2012
295: 167-176
|
| 28973161 |
Farhan SMK et al. et al.:
Identification of a novel synaptic protein, TMTC3, involved in periventricular nodular heterotopia with intellectual disability and epilepsy
Hum. Mol. Genet.
2017
26: 4278-4289
|
| 17273967 |
Basel-Vanagaite L et al. et al.:
Autosomal recessive ichthyosis with hypotrichosis caused by a mutation in ST14, encoding type II transmembrane serine protease matriptase
Am. J. Hum. Genet.
2007
80: 467-477
|
| 27316827 |
Yan X et al.:
Activation of proHGF by St14 induces mouse embryonic stem cell differentiation
Protein Cell
2016
7: 601-605
|
| 19717635 |
List K et al.:
Epithelial integrity is maintained by a matriptase-dependent proteolytic pathway
Am. J. Pathol.
2009
175: 1453-1463
|
| 23472874 |
Reinhardt P et al. et al.:
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression
Cell Stem Cell
2013
12: 354-367
|
| 9763659 |
Nakayama T et al.:
Hemizygous deletion of the HPC-1/syntaxin 1A gene (STX1A) in patients with Williams syndrome
Cytogenet. Cell Genet.
1998
82: 49-51
|
| 20422020 |
Gao MC et al.:
Intelligence in Williams Syndrome is related to STX1A, which encodes a component of the presynaptic SNARE complex
PLoS ONE
2010
5
|
| 19527686 |
Makeyev AV et al.:
New TFII-I family target genes involved in embryonic development
Biochem. Biophys. Res. Commun.
2009
386: 554-558
|
| 20468056 |
Ching MS et al. et al.:
Deletions of NRXN1 (neurexin-1) predispose to a wide spectrum of developmental disorders
Am. J. Med. Genet. B Neuropsychiatr. Genet.
2010
153B: 937-947
|
| 22617343 |
Schaaf CP et al. et al.:
Phenotypic spectrum and genotype-phenotype correlations of NRXN1 exon deletions
Eur. J. Hum. Genet.
2012
20: 1240-1247
|
| 23918801 |
Bogani D et al.:
The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo
Mol. Cell. Biol.
2013
33: 3936-3950
|
| 30566373 |
Ma S et al.:
The Hippo Pathway: Biology and Pathophysiology
Annu. Rev. Biochem.
2019
88: 577-604
|
| 21984414 |
Pedrotti S et al.:
The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator
Nucleic Acids Res.
2012
40: 1021-1032
|
| 30198493 |
Shen C et al. et al.:
Strawberry Notch 1 (SBNO1) promotes proliferation of spermatogonial stem cells via the noncanonical Wnt pathway in mice
Asian J. Androl.
2019
21: 345-350
|
| 28401892 |
Watanabe Y et al.:
Notch and Hippo signaling converge on Strawberry Notch 1 (Sbno1) to synergistically activate Cdx2 during specification of the trophectoderm
Sci Rep
2017
7: 46135
|
| 31242033 |
Jensen LD et al. et al.:
Disruption of the Extracellular Matrix Progressively Impairs Central Nervous System Vascular Maturation Downstream of beta-Catenin Signaling
Arterioscler. Thromb. Vasc. Biol.
2019
39: 1432-1447
|
| 29140246 |
Zhang H et al.:
An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis
|
| 23211737 |
Maserati M et al.:
Identification of four genes required for mammalian blastocyst formation
Zygote
2014
22: 331-339
|
| 29429573 |
Esteve C et al. et al.:
Loss-of-Function Mutations in UNC45A Cause a Syndrome Associating Cholestasis, Diarrhea, Impaired Hearing, and Bone Fragility
Am. J. Hum. Genet.
2018
102: 364-374
|
| 27798045 |
Amiri-Yekta A et al. et al.:
Whole-exome sequencing of familial cases of multiple morphological abnormalities of the sperm flagella (MMAF) reveals new DNAH1 mutations
Hum. Reprod.
2016
31: 2872-2880
|
| 28188861 |
Strzelecka-Kiliszek A et al.:
Functions of Rho family of small GTPases and Rho-associated coiled-coil kinases in bone cells during differentiation and mineralization
Biochim Biophys Acta Gen Subj
2017
1861: 1009-1023
|
| 31040401 |
Xu Q et al. et al.:
SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development
Nat. Genet.
2019
51: 844-856
|
| 9126485 |
Sirotkin H et al.:
Identification of a new human catenin gene family member (ARVCF) from the region deleted in velo-cardio-facial syndrome
Genomics
1997
41: 75-83
|
| 27450648 |
Dias AT et al. et al.:
Post-mortem cytogenomic investigations in patients with congenital malformations
Exp. Mol. Pathol.
2016
101: 116-123
|
| 29258758 |
Wang X et al.:
Inhibition of thymidylate synthase affects neural tube development in mice
Reprod. Toxicol.
2018
76: 17-25
|
| 27182062 |
et al.:
Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin
J. Cell. Sci.
2016
129: 2120-2123
|
| 31028279 |
Noe N et al.:
Mesenchyme-specific deletion of Tgf-beta1 in the embryonic lung disrupts branching morphogenesis and induces lung hypoplasia
Lab. Invest.
2019
99: 1363-1375
|
| 32359161 |
Karvas RM et al.:
Use of a human embryonic stem cell model to discover GABRP, WFDC2, VTCN1 and ACTC1 as markers of early first trimester human trophoblast
Mol. Hum. Reprod.
2020
26: 425-440
|
| 17504919 |
Sarraj MA et al.:
Expression of Wsb2 in the developing and adult mouse testis
Reproduction
2007
133: 753-761
|
| 21862448 |
Oeschger FM et al.:
Gene expression analysis of the embryonic subplate
Cereb. Cortex
2012
22: 1343-1359
|
| 27031267 |
et al.:
De Novo 1.77-Mb Microdeletion of 10q22.2q22.3 in a Girl With Developmental Delay, Speech Delay, Congenital Cleft Palate, and Bilateral Hearing Impairment
Cleft Palate Craniofac. J.
2017
54: 343-350
|
| 22894909 |
Barbaux S et al. et al.:
A genome-wide approach reveals novel imprinted genes expressed in the human placenta
Epigenetics
2012
7: 1079-1090
|
| 28864461 |
Griffin NG et al.:
Somatic uniparental disomy of Chromosome 16p in hemimegalencephaly
|
| 30242100 |
Inoue T et al. et al.:
Molecular and clinical analyses of two patients with UPD(16)mat detected by screening 94 patients with Silver-Russell syndrome phenotype of unknown aetiology
J. Med. Genet.
2019
56: 413-418
|
| 32576657 |
Yamazawa K et al. et al.:
Loss of imprinting of the human-specific imprinted gene ZNF597 causes prenatal growth retardation and dysmorphic features: implications for phenotypic overlap with Silver-Russell syndrome
|
| 30136190 |
Chaudhary P et al.:
HGF promotes HTR-8/SVneo cell migration through activation of MAPK/PKA signaling leading to up-regulation of WNT ligands and integrins that target beta-catenin
Mol. Cell. Biochem.
2019
453: 11-32
|
| 10742111 |
Littlewood Evans A et al.:
Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1
Nat. Genet.
2000
24: 424-428
|
| 29615062 |
Ardissone A et al. et al.:
KARS-related diseases: progressive leukoencephalopathy with brainstem and spinal cord calcifications as new phenotype and a review of literature
Orphanet J Rare Dis
2018
13: 45
|
| 9585423 |
Guttinger M et al.:
Epithelial V-like antigen (EVA), a novel member of the immunoglobulin superfamily, expressed in embryonic epithelia with a potential role as homotypic adhesion molecule in thymus histogenesis
J. Cell Biol.
1998
141: 1061-1071
|
| 21858136 |
Ruiz-Ferrer M et al.:
Expression of PROKR1 and PROKR2 in human enteric neural precursor cells and identification of sequence variants suggest a role in HSCR
PLoS ONE
2011
6
|
| 27736039 |
Wang CY et al.:
Primary Cilium-Regulated EG-VEGF Signaling Facilitates Trophoblast Invasion
J. Cell. Physiol.
2017
232: 1467-1477
|
| 32374670 |
Hadchouel A et al.:
Overexpression of Spock2 in mice leads to altered lung alveolar development and worsens lesions induced by hyperoxia
Am. J. Physiol. Lung Cell Mol. Physiol.
2020
319: L71-L81
|
| 11760020 |
Lang-Muritano M et al.:
A novel mutation in the anti-mullerian hormone gene as cause of persistent mullerian duct syndrome
Eur J Pediatr
2001
160: 652-654
|
| 29293958 |
Imtiaz A et al. et al.:
CDC14A phosphatase is essential for hearing and male fertility in mouse and human
Hum Mol Genet
2018
27: 780-798
|
| 30982678 |
Samarajeewa A et al.:
Therapeutic Potential of Wnt and Notch Signaling and Epigenetic Regulation in Mammalian Sensory Hair Cell Regeneration
Mol Ther
2019
27: 904-911
|
| 14643677 |
Baxter LL et al.:
Pmel17 expression is Mitf-dependent and reveals cranial melanoblast migration during murine development
Gene Expr Patterns
2003
3: 703-707
|
| 30321403 |
Veland N et al. et al.:
DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells
Nucleic Acids Res
2019
47: 152-167
|
| 11719692 |
Bourc'his D et al.:
Dnmt3L and the establishment of maternal genomic imprints
Science
2001
294: 2536-2539
|
| 32878077 |
Cui D et al.:
Dnmt3a2/Dnmt3L Overexpression in the Dopaminergic System of Mice Increases Exercise Behavior through Signaling Changes in the Hypothalamus
|
| 33268382 |
Passaro F et al. et al.:
YAP contributes to DNA methylation remodeling upon mouse embryonic stem cell differentiation
|
| 28228259 |
Heo J et al. et al.:
Sirt1 Regulates DNA Methylation and Differentiation Potential of Embryonic Stem Cells by Antagonizing Dnmt3l
Cell Rep
2017
18: 1930-1945
|
| 24952347 |
Pacaud R et al.:
DNMT3L interacts with transcription factors to target DNMT3L/DNMT3B to specific DNA sequences: role of the DNMT3L/DNMT3B/p65-NFkappaB complex in the (de-)methylation of TRAF1
Biochimie
2014
104: 36-49
|
| 26608607 |
Polesskaya A et al.:
Post-transcriptional modulation of interleukin 8 by CNOT6L regulates skeletal muscle differentiation
Biochim Biophys Acta
2016
1863: 263-270
|
| 30628007 |
Groves JA et al.:
Identification of Novel Binding Partners for Transcription Factor Emx2
Protein J
2019
38: 2-11
|
| 20152827 |
Holley M et al.:
Emx2 and early hair cell development in the mouse inner ear
Dev Biol
2010
340: 547-556
|
| 33138308 |
Chalabi Hagkarim N et al.:
The Regulatory Properties of the Ccr4-Not Complex
|
| 16955138 |
Engelking LJ et al.:
Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin
J Clin Invest
2006
116: 2356-2365
|
| 30460077 |
Jo Y et al.:
Regulation of INSIG2 by microRNA-96
Anim Cells Syst (Seoul)
2017
21: 263-268
|
| 30122083 |
Memon N et al.:
Developmental regulation of the gut-liver (FGF19-CYP7A1) axis in neonates
J Matern Fetal Neonatal Med
2020
33: 987-992
|
| 23934687 |
Krejci P et al.:
Expression of FGF19 in human embryonic stem cells
Stem Cells
2013
31: 2582-2584
|
| 31192996 |
Kiratli Nalbant E et al.:
A rare case of prolidase deficiency with situs inversus totalis, identified by a novel mutation in the PEPD gene
JAAD Case Rep
2019
5: 436-438
|
| 33477899 |
Baszanowska W et al.:
Extracellular Prolidase (PEPD) Induces Anabolic Processes through EGFR, beta1-integrin, and IGF-1R Signaling Pathways in an Experimental Model of Wounded Fibroblasts
|
| 19308961 |
Falik-Zaccai TC et al.:
A broad spectrum of developmental delay in a large cohort of prolidase deficiency patients demonstrates marked interfamilial and intrafamilial phenotypic variability
Am J Med Genet B Neuropsychiatr Genet
2010
153B: 46-56
|
| 25308848 |
Insolia V et al.:
Brain morphological defects in prolidase deficient mice: first report
Eur J Histochem
2014
58: 2417
|
| 18340504 |
Lupi A et al.:
Human prolidase and prolidase deficiency: an overview on the characterization of the enzyme involved in proline recycling and on the effects of its mutations
Amino Acids
2008
35: 739-752
|
| 33531666 |
Shao DD et al. et al.:
A recurrent, homozygous EMC10 frameshift variant is associated with a syndrome of developmental delay with variable seizures and dysmorphic features
Genet Med
2021
23: 1158-1162
|
| 32869858 |
Umair M et al. et al.:
EMC10 homozygous variant identified in a family with global developmental delay, mild intellectual disability, and speech delay
Clin Genet
2020
98: 555-561
|
| 26942288 |
Harel T et al. et al.:
Monoallelic and Biallelic Variants in EMC1 Identified in Individuals with Global Developmental Delay, Hypotonia, Scoliosis, and Cerebellar Atrophy
Am J Hum Genet
2016
98: 562-570
|
| 31904590 |
Marquez J et al.:
Disrupted ER membrane protein complex-mediated topogenesis drives congenital neural crest defects
J Clin Invest
2020
130: 813-826
|
| 33605987 |
Cao X et al.:
EMC3 Is Essential for Retinal Organization and Neurogenesis During Mouse Retinal Development
Invest Ophthalmol Vis Sci
2021
62: 31
|
| 29698489 |
De Pace R et al. et al.:
Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome
PLoS Genet
2018
14
|
| 10436028 |
Hirst J et al.:
Characterization of a fourth adaptor-related protein complex
Mol Biol Cell
1999
10: 2787-2802
|
| 32123383 |
author information missing
article information missing
|
| 23994616 |
author information missing
article information missing
|
| 16165280 |
author information missing
article information missing
|
| 20133598 |
author information missing
article information missing
|
| 21078877 |
author information missing
article information missing
|
| 35042660 |
author information missing
article information missing
|
| 33277614 |
author information missing
article information missing
|
| 21858081 |
author information missing
article information missing
|
| 23922682 |
author information missing
article information missing
|
| 33530472 |
author information missing
article information missing
|
| 27037025 |
author information missing
article information missing
|
| 22177091 |
author information missing
article information missing
|
| 29460436 |
author information missing
article information missing
|
| 28301459 |
author information missing
article information missing
|
| 11528384 |
author information missing
article information missing
|
| 26822784 |
author information missing
article information missing
|
| 29446546 |
author information missing
article information missing
|
| 15706485 |
author information missing
article information missing
|
| 29460469 |
author information missing
article information missing
|
| 26235985 |
author information missing
article information missing
|
| 28280134 |
author information missing
article information missing
|
| 9988267 |
author information missing
article information missing
|
| 16252232 |
author information missing
article information missing
|
| 33199684 |
author information missing
article information missing
|
| 18178619 |
author information missing
article information missing
|
| 18690212 |
author information missing
article information missing
|
| 17507929 |
author information missing
article information missing
|
| 15973356 |
author information missing
article information missing
|
| 19129173 |
author information missing
article information missing
|
| 18425797 |
author information missing
article information missing
|
| 19864492 |
author information missing
article information missing
|
| 26643732 |
author information missing
article information missing
|
| 29130651 |
author information missing
article information missing
|
| 35406739 |
author information missing
article information missing
|
| 29460012 |
author information missing
article information missing
|
| 34573339 |
author information missing
article information missing
|
| 32992671 |
author information missing
article information missing
|
| 32737436 |
author information missing
article information missing
|
| 30733656 |
author information missing
article information missing
|
| 17549790 |
author information missing
article information missing
|
| 39010945 |
author information missing
article information missing
|
| 28686854 |
Bayram Y et al. et al.:
REST Final-Exon-Truncating Mutations Cause Hereditary Gingival Fibromatosis
Am. J. Hum. Genet.
2017
101: 149-156
|
| 27774744 |
Zarate YA et al.:
SATB2-associated syndrome: Mechanisms, phenotype, and practical recommendations
Am. J. Med. Genet. A
2017
173: 327-337
|
| 24411565 |
Zhao X et al.:
The role of SATB2 in skeletogenesis and human disease
Cytokine Growth Factor Rev.
2014
25: 35-44
|
| 26084711 |
Lumish HS et al.:
Brief Report: SETD2 Mutation in a Child with Autism, Intellectual Disabilities and Epilepsy
J Autism Dev Disord
2015
45: 3764-3770
|
| 31643139 |
Marzin P et al.:
SETD2 related overgrowth syndrome: Presentation of four new patients and review of the literature
Am J Med Genet C Semin Med Genet
2019
181: 509-518
|
| 29716999 |
Zuo X et al.:
The histone methyltransferase SETD2 is required for expression of acrosin-binding protein 1 and protamines and essential for spermiogenesis in mice
J. Biol. Chem.
2018
293: 9188-9197
|
| 20133625 |
Hu M et al. et al.:
Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 2956-2961
|
| 19332550 |
Yuan W et al.:
Heterogeneous nuclear ribonucleoprotein L Is a subunit of human KMT3a/Set2 complex required for H3 Lys-36 trimethylation activity in vivo
J. Biol. Chem.
2009
284
|
| 32849799 |
Li J et al.:
SET Domain Containing 2 Deficiency in Myelodysplastic Syndrome
Front Genet
2020
11: 794
|
| 28165011 |
Palmieri M et al. et al.:
mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases
Nat Commun
2017
8: 14338
|
| 28553959 |
Yost S et al. et al.:
Biallelic TRIP13 mutations predispose to Wilms tumor and chromosome missegregation
Nat. Genet.
2017
49: 1148-1151
|
| 30610172 |
Sergeeva OA et al.:
Anthrax toxin requires ZDHHC5-mediated palmitoylation of its surface-processing host enzymes
Proc. Natl. Acad. Sci. U.S.A.
2019
116: 1279-1288
|
| 18953340 |
Cizkova A et al. et al.:
TMEM70 mutations cause isolated ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy
Nat. Genet.
2008
40: 1288-1290
|
| 24454898 |
Zaveri HP et al. et al.:
Identification of critical regions and candidate genes for cardiovascular malformations and cardiomyopathy associated with deletions of chromosome 1p36
PLoS ONE
2014
9
|
| 8326488 |
Evans DG et al.:
Complications of the naevoid basal cell carcinoma syndrome: results of a population based study
J. Med. Genet.
1993
30: 460-464
|
| 23479190 |
Fujii K et al.:
Frameshift mutation in the PTCH2 gene can cause nevoid basal cell carcinoma syndrome
Fam. Cancer
2013
12: 611-614
|
| 18285427 |
Fan Z et al.:
A missense mutation in PTCH2 underlies dominantly inherited NBCCS in a Chinese family
J. Med. Genet.
2008
45: 303-308
|
| 19533801 |
Pastorino L et al.:
Identification of a SUFU germline mutation in a family with Gorlin syndrome
Am. J. Med. Genet. A
2009
149
|
| 27236920 |
Twigg SRF et al. et al.:
A Recurrent Mosaic Mutation in SMO, Encoding the Hedgehog Signal Transducer Smoothened, Is the Major Cause of Curry-Jones Syndrome
Am. J. Hum. Genet.
2016
98: 1256-1265
|
| 26424145 |
Hollstein R et al. et al.:
HACE1 deficiency causes an autosomal recessive neurodevelopmental syndrome
J. Med. Genet.
2015
52: 797-803
|
| 27697305 |
Lee HF et al.:
Early cardiac involvement in an infantile Sandhoff disease case with novel mutations
Brain Dev.
2017
39: 171-176
|
| 18758829 |
Zampieri S et al.:
Molecular and functional analysis of the HEXB gene in Italian patients affected with Sandhoff disease: identification of six novel alleles
Neurogenetics
2009
10: 49-58
|
| 30075786 |
Tavasoli AR et al.:
Clinical presentation and outcome in infantile Sandhoff disease: a case series of 25 patients from Iranian neurometabolic bioregistry with five novel mutations
Orphanet J Rare Dis
2018
13: 130
|
| 22332140 |
Sinnamon JR et al.:
Hnrpab regulates neural development and neuron cell survival after glutamate stimulation
RNA
2012
18: 704-719
|
| 20890276 |
Endele S et al. et al.:
Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes
Nat. Genet.
2010
42: 1021-1026
|
| 22964307 |
Inagaki A et al.:
Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsia
Placenta
2012
33: 919-926
|
| 22778138 |
Wang LJ et al.:
High-temperature requirement protein A4 (HtrA4) suppresses the fusogenic activity of syncytin-1 and promotes trophoblast invasion
Mol. Cell. Biol.
2012
32: 3707-3717
|
| 32853347 |
Wiegel RE et al.:
Determinants of Maternal Renin-Angiotensin-Aldosterone-System Activation in Early Pregnancy: Insights From 2 Cohorts
|
| 23643382 |
Miraoui H et al. et al.:
Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism
Am. J. Hum. Genet.
2013
92: 725-743
|
| 15239952 |
Torii S et al.:
Sef is a spatial regulator for Ras/MAP kinase signaling
Dev. Cell
2004
7: 33-44
|
| 28488682 |
Umair M et al.:
Exome sequencing revealed a splice site variant in the IQCE gene underlying post-axial polydactyly type A restricted to lower limb
Eur. J. Hum. Genet.
2017
25: 960-965
|
| 24582806 |
Pusapati GV et al.:
EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia
Dev. Cell
2014
28: 483-496
|
| 2933589 |
author information missing
Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia
Nature
1985
318: 470-472
|
| 24439109 |
Humbert C et al. et al.:
Integrin alpha 8 recessive mutations are responsible for bilateral renal agenesis in humans
Am. J. Hum. Genet.
2014
94: 288-294
|
| 20920668 |
McLaughlin HM et al. et al.:
Compound heterozygosity for loss-of-function lysyl-tRNA synthetase mutations in a patient with peripheral neuropathy
Am. J. Hum. Genet.
2010
87: 560-566
|
| 23768514 |
Santos-Cortez RL et al. et al.:
Mutations in KARS, encoding lysyl-tRNA synthetase, cause autosomal-recessive nonsyndromic hearing impairment DFNB89
Am. J. Hum. Genet.
2013
93: 132-140
|
| 26508575 |
Liu X et al.:
Identification of candidate genes for familial early-onset essential tremor
Eur. J. Hum. Genet.
2016
24: 1009-1015
|
| 9305895 |
Salinas M et al.:
New modulatory alpha subunits for mammalian Shab K+ channels
J. Biol. Chem.
1997
272
|
| 21220025 |
Fukuda T et al.:
Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly
Mol. Cell. Neurosci.
2011
46: 614-624
|
| 25299227 |
Liu J et al.:
Reconstruction of the gene regulatory network involved in the sonic hedgehog pathway with a potential role in early development of the mouse brain
PLoS Comput. Biol.
2014
10
|
| 28462915 |
Gorelik A et al.:
Developmental activities of the complement pathway in migrating neurons
Nat Commun
2017
8: 15096
|
| 30427554 |
Fujita A et al. et al.:
Homozygous splicing mutation in NUP133 causes Galloway-Mowat syndrome
Ann. Neurol.
2018
84: 814-828
|
| 23395638 |
Ohtaka-Maruyama C et al.:
RP58 regulates the multipolar-bipolar transition of newborn neurons in the developing cerebral cortex
Cell Rep
2013
3: 458-471
|
| 16481321 |
Tanaka H et al.:
Pragmin, a novel effector of Rnd2 GTPase, stimulates RhoA activity
J. Biol. Chem.
2006
281
|
| 31069631 |
Carrano N et al.:
The Synaptonuclear Messenger RNF10 Acts as an Architect of Neuronal Morphology
Mol. Neurobiol.
2019
56: 7583-7593
|
| 26977767 |
Dinamarca MC et al. et al.:
Ring finger protein 10 is a novel synaptonuclear messenger encoding activation of NMDA receptors in hippocampus
Elife
2016
5
|
| 18941509 |
Hoshikawa S et al.:
A novel function of RING finger protein 10 in transcriptional regulation of the myelin-associated glycoprotein gene and myelin formation in Schwann cells
PLoS ONE
2008
3: e3464
|
| 31794429 |
van Gastel J et al.:
The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage
Aging (Albany NY)
2019
11
|
| 28377535 |
Aouizerat BE et al.:
GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease
BMC Cardiovasc Disord
2011
11: 29
|
| 21123581 |
Apostolova G et al.:
The sympathetic neurotransmitter switch depends on the nuclear matrix protein Satb2
J. Neurosci.
2010
30
|
| 18385322 |
Amin ND et al.:
Cyclin-dependent kinase 5 phosphorylation of human septin SEPT5 (hCDCrel-1) modulates exocytosis
J. Neurosci.
2008
28: 3631-3643
|
| 15355307 |
Beites CL et al.:
The septin Sept5/CDCrel-1 competes with alpha-SNAP for binding to the SNARE complex
Biochem. J.
2005
385: 347-353
|
| 26830932 |
Oka M et al.:
A novel HYLS1 homozygous mutation in living siblings with Joubert syndrome
Clin. Genet.
2016
89: 739-743
|
| 21767234 |
Tsang CW et al.:
Characterization of presynaptic septin complexes in mammalian hippocampal neurons
Biol. Chem.
2011
392: 739-749
|
| 20680483 |
Park HJ et al.:
Ankyrin repeat-rich membrane spanning/Kidins220 protein interacts with mammalian Septin 5
Mol. Cells
2010
30: 143-148
|
| 15200239 |
Takehashi M et al.:
Expression of septin 3 isoforms in human brain
Gene Expr.
2004
11: 271-278
|
| 11322766 |
Methner A et al.:
Human septin 3 on chromosome 22q13.2 is upregulated by neuronal differentiation
Biochem. Biophys. Res. Commun.
2001
283: 48-56
|
| 29294103 |
Shen T et al.:
Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder
Nucleic Acids Res.
2018
46: 2290-2307
|
| 23393310 |
Edvardson S et al. et al.:
Agenesis of corpus callosum and optic nerve hypoplasia due to mutations in SLC25A1 encoding the mitochondrial citrate transporter
J. Med. Genet.
2013
50: 240-245
|
| 32326436 |
Chleilat E et al.:
TGF-beta Signaling Regulates SLC8A3 Expression and Prevents Oxidative Stress in Developing Midbrain Dopaminergic and Dorsal Raphe Serotonergic Neurons
|
| 31745231 |
Han KA et al.:
Slitrk2 controls excitatory synapse development via PDZ-mediated protein interactions
Sci Rep
2019
9: 17094
|
| 25449700 |
Chauvin S et al.:
Neuronal stathmins: a family of phosphoproteins cooperating for neuronal development, plasticity and regeneration
Prog. Neurobiol.
2015
126: 1-18
|
| 26091538 |
Schrauwen I et al. et al.:
A De Novo Mutation in TEAD1 Causes Non-X-Linked Aicardi Syndrome
Invest. Ophthalmol. Vis. Sci.
2015
56: 3896-3904
|
| 25527292 |
Artegiani B et al.:
Tox: a multifunctional transcription factor and novel regulator of mammalian corticogenesis
EMBO J.
2015
34: 896-910
|
| 18480156 |
Ishii M et al.:
Spatiotemporal expression of chondroitin sulfate sulfotransferases in the postnatal developing mouse cerebellum
Glycobiology
2008
18: 602-614
|
| 25330800 |
McMillan HJ et al.:
Congenital Visual Impairment and Progressive Microcephaly Due to Lysyl-Transfer Ribonucleic Acid (RNA) Synthetase (KARS) Mutations: The Expanding Phenotype of Aminoacyl-Transfer RNA Synthetase Mutations in Human Disease
J. Child Neurol.
2015
30: 1037-1043
|
| 28887846 |
Zhou XL et al.:
Mutations in KARS cause early-onset hearing loss and leukoencephalopathy: Potential pathogenic mechanism
Hum. Mutat.
2017
38: 1740-1750
|
| 16169847 |
Wolfe CL et al.:
A three-dimensional working model of the multienzyme complex of aminoacyl-tRNA synthetases based on electron microscopic placements of tRNA and proteins
J. Biol. Chem.
2005
280
|
| 30715177 |
Itoh M et al. et al.:
Biallelic KARS pathogenic variants cause an early-onset progressive leukodystrophy
Brain
2019
142: 560-573
|
| 31116475 |
Scheidecker S et al. et al.:
Mutations in KARS cause a severe neurological and neurosensory disease with optic neuropathy
Hum. Mutat.
2019
40: 1826-1840
|
| 10973986 |
Wood JD et al.:
Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription
J Cell Biol
2000
150: 939-948
|
| 32439656 |
Pleiner T et al.:
Structural basis for membrane insertion by the human ER membrane protein complex
Science
2020
369: 433-436
|
| 29391579 |
author information missing
article information missing
|
| 28626029 |
author information missing
article information missing
|
| 16828797 |
author information missing
article information missing
|
| 18930054 |
author information missing
article information missing
|
| 32843486 |
author information missing
article information missing
|
| 16025134 |
author information missing
article information missing
|
| 34983975 |
author information missing
article information missing
|
| 33719327 |
author information missing
article information missing
|
| 33208359 |
author information missing
article information missing
|
| 32877400 |
author information missing
article information missing
|
| 30853973 |
author information missing
article information missing
|
| 28003315 |
author information missing
article information missing
|
| 22279557 |
author information missing
article information missing
|
| 32901138 |
author information missing
article information missing
|
| 31794024 |
author information missing
article information missing
|
| 30843302 |
author information missing
article information missing
|
| 27707803 |
author information missing
article information missing
|
| 32347653 |
author information missing
article information missing
|
| 30167849 |
author information missing
article information missing
|
| 30715179 |
author information missing
article information missing
|
| 31429971 |
author information missing
article information missing
|
| 28132692 |
author information missing
article information missing
|
| 17254023 |
author information missing
article information missing
|
| 17699672 |
author information missing
article information missing
|
| 12725910 |
author information missing
article information missing
|
| 34869110 |
author information missing
article information missing
|
| 28781078 |
author information missing
article information missing
|
| 9278521 |
author information missing
article information missing
|
| 34724258 |
author information missing
article information missing
|
| 22325201 |
author information missing
article information missing
|
| 21841779 |
author information missing
article information missing
|
| 21785126 |
author information missing
article information missing
|
| 21846720 |
author information missing
article information missing
|
| 28479296 |
author information missing
article information missing
|
| 31230721 |
author information missing
article information missing
|
| 38387458 |
author information missing
article information missing
|
| 39655047 |
author information missing
article information missing
|
| 35626875 |
author information missing
article information missing
|
| 25043029 |
author information missing
article information missing
|
| 34942119 |
author information missing
article information missing
|
| 20921411 |
author information missing
article information missing
|
| 19448625 |
author information missing
article information missing
|
| 20006513 |
author information missing
article information missing
|
| 17485678 |
Tingley WG et al.:
Gene-trapped mouse embryonic stem cell-derived cardiac myocytes and human genetics implicate AKAP10 in heart rhythm regulation
Proc. Natl. Acad. Sci. U.S.A.
2007
104: 8461-8466
|
| 26419238 |
Atik T et al. et al.:
Novel MASP1 mutations are associated with an expanded phenotype in 3MC1 syndrome
Orphanet J Rare Dis
2015
10: 128
|
| 26789649 |
Urquhart J et al. et al.:
Exploring the genetic basis of 3MC syndrome: Findings in 12 further families
Am J Med Genet A
2016
170
|
| 30449657 |
Tripathy R et al. et al.:
Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations
Neuron
2018
100: 1354-1368.e5
|
| 27583304 |
Depondt C et al.:
MME mutation in dominant spinocerebellar ataxia with neuropathy (SCA43)
Neurol Genet
2016
2: e94
|
| 26991897 |
Higuchi Y et al. et al.:
Mutations in MME cause an autosomal-recessive Charcot-Marie-Tooth disease type 2
Ann. Neurol.
2016
79: 659-672
|
| 9468285 |
Nauseef WM et al.:
Pattern of inheritance in hereditary myeloperoxidase deficiency associated with the R569W missense mutation
J. Leukoc. Biol.
1998
63: 264-269
|
| 25077174 |
Handley MT et al.:
Loss of ALDH18A1 function is associated with a cellular lipid droplet phenotype suggesting a link between autosomal recessive cutis laxa type 3A and Warburg Micro syndrome
Mol Genet Genomic Med
2014
2: 319-325
|
| 29982980 |
Bademci G et al. et al.:
MPZL2 is a novel gene associated with autosomal recessive nonsyndromic moderate hearing loss
Hum. Genet.
2018
137: 479-486
|
| 25080166 |
Vincent JB et al. et al.:
Phosphoserine phosphatase (PSPH) gene mutation in an intellectual disability family from Pakistan
Clin. Genet.
2015
87: 296-298
|
| 32594192 |
Murtas G et al.:
L-serine synthesis via the phosphorylated pathway in humans
|
| 20967465 |
Borck G et al.:
A homozygous RAB3GAP2 mutation causes Warburg Micro syndrome
Hum. Genet.
2011
129: 45-50
|
| 25495476 |
Spang N et al. et al.:
RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy
Autophagy
2014
10: 2297-2309
|
| 2738902 |
Harbord MG et al.:
Microcephaly, mental retardation, cataracts, and hypogonadism in sibs: Martsolfs syndrome
J. Med. Genet.
1989
26: 397-400
|
| 16532399 |
Aligianis IA et al. et al.:
Mutation in Rab3 GTPase-activating protein (RAB3GAP) noncatalytic subunit in a kindred with Martsolf syndrome
Am. J. Hum. Genet.
2006
78: 702-707
|
| 24548729 |
Durdiakova J et al.:
STX1A and Asperger syndrome: a replication study
Mol Autism
2014
5: 14
|
| 31341471 |
Yan N et al.:
Aberrant Histone Methylation in Patients with Graves Disease
Int J Endocrinol
2019
2019
|
| 30414981 |
author information missing
article information missing
|
| 10368122 |
Satoda M et al.:
Char syndrome, an inherited disorder with patent ductus arteriosus, maps to chromosome 6p12-p21
Circulation
1999
99: 3036-3042
|
| 11505339 |
Zhao F et al.:
Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation
Am. J. Hum. Genet.
2001
69: 695-703
|
| 21829553 |
Zhao F et al.:
A heart-hand syndrome gene: Tfap2b plays a critical role in the development and remodeling of mouse ductus arteriosus and limb patterning
PLoS ONE
2011
6
|
| 31012281 |
Edward HL et al.:
A novel missense mutation in TFAP2B associated with Char syndrome and central diabetes insipidus
Am. J. Med. Genet. A
2019
179: 1299-1303
|
| 10943845 |
Bochar DA et al.:
BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer
Cell
2000
102: 257-265
|
| 31273213 |
Filatova A et al.:
Mutations in SMARCB1 and in other Coffin-Siris syndrome genes lead to various brain midline defects
Nat Commun
2019
10: 2966
|
| 29907796 |
Diets IJ et al.:
A recurrent de novo missense pathogenic variant in SMARCB1 causes severe intellectual disability and choroid plexus hyperplasia with resultant hydrocephalus
Genet. Med.
2019
21: 572-579
|
| 29868776 |
Nahorski MS et al. et al.:
Biallelic UFM1 and UFC1 mutations expand the essential role of ufmylation in brain development
Brain
2018
141: 1934-1945
|
| 29226520 |
Cohen I et al.:
A novel homozygous SLC25A1 mutation with impaired mitochondrial complex V: Possible phenotypic expansion
Am. J. Med. Genet. A
2018
176: 330-336
|
| 18703424 |
Hu Y et al.:
RGS22, a novel testis-specific regulator of G-protein signaling involved in human and mouse spermiogenesis along with GNA12/13 subunits
Biol. Reprod.
2008
79: 1021-1029
|
| 26646932 |
Snyder E et al.:
Compound Heterozygosity for Y Box Proteins Causes Sterility Due to Loss of Translational Repression
PLoS Genet.
2015
11
|
| 25107366 |
Ruan YC et al.:
CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation through the ZONAB pathway
J. Cell. Sci.
2014
127: 4396-4408
|
| 29087293 |
Bailey AS et al.:
The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline
|
| 29619874 |
Worku T et al.:
Regulatory roles of ephrinA5 and its novel signaling pathway in mouse primary granulosa cell apoptosis and proliferation
Cell Cycle
2018
17: 892-902
|
| 21698294 |
Zhuang XJ et al.:
SLXL1, a novel acrosomal protein, interacts with DKKL1 and is involved in fertilization in mice
PLoS One
2011
6
|
| 19176879 |
Reynard LN et al.:
The multi-copy mouse gene Sycp3-like Y-linked (Sly) encodes an abundant spermatid protein that interacts with a histone acetyltransferase and an acrosomal protein
Biol Reprod
2009
81: 250-257
|
| 25973848 |
author information missing
article information missing
|
| 27506944 |
Wu Y et al.:
RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors
Oncotarget
2016
7
|
| 28852709 |
Gorcenco S et al. et al.:
Ataxia-pancytopenia syndrome with SAMD9L mutations
Neurol Genet
2017
3: e183
|
| 21412262 |
Jiang Q et al.:
The Samd9L gene: transcriptional regulation and tissue-specific expression in mouse development
J. Invest. Dermatol.
2011
131: 1428-1434
|
| 32808377 |
Vaughan D et al.:
Ataxia pancytopenia syndrome due to SAMD9L mutation presenting as demyelinating neuropathy
|
| 18308289 |
Berkovic SF et al. et al.:
Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosis
Am. J. Hum. Genet.
2008
82: 673-684
|
| 24389070 |
Gonzalez A et al.:
Lysosomal integral membrane protein-2: a new player in lysosome-related pathology
Mol. Genet. Metab.
2014
111: 84-91
|
| 27068304 |
Vijay S et al.:
Exclusive expression of the Rab11 effector SH3TC2 in Schwann cells links integrin-alpha6 and myelin maintenance to Charcot-Marie-Tooth disease type 4C
Biochim. Biophys. Acta
2016
1862: 1279-1290
|
| 9109432 |
Oelkers P et al.:
Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2)
J. Clin. Invest.
1997
99: 1880-1887
|
| 30599477 |
Kwak MJ et al.:
Clinical genetics of defects in thyroid hormone synthesis
Ann Pediatr Endocrinol Metab
2018
23: 169-175
|
| 9662405 |
Schultheis PJ et al. et al.:
Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger
Nat. Genet.
1998
19: 282-285
|
| 21282559 |
Banday AA et al.:
Oxidative stress causes renal angiotensin II type 1 receptor upregulation, Na+/H+ exchanger 3 overstimulation, and hypertension
Hypertension
2011
57: 452-459
|
| 26358773 |
Janecke AR et al. et al.:
Reduced sodium/proton exchanger NHE3 activity causes congenital sodium diarrhea
Hum. Mol. Genet.
2015
24: 6614-6623
|
| 31671693 |
Malcher A et al. et al.:
Novel Mutations Segregating with Complete Androgen Insensitivity Syndrome and their Molecular Characteristics
|
| 26003402 |
Tawamie H et al.:
Recurrent null mutation in SPG20 leads to Troyer syndrome
Mol. Cell. Probes
2015
29: 315-318
|
| 28875386 |
Bizzari S et al.:
Novel SPG20 mutation in an extended family with Troyer syndrome
Metab Brain Dis
2017
32: 2155-2159
|
| 22619377 |
Renvoise B et al.:
Spg20-/- mice reveal multimodal functions for Troyer syndrome protein spartin in lipid droplet maintenance, cytokinesis and BMP signaling
Hum. Mol. Genet.
2012
21: 3604-3618
|
| 21559443 |
Joshi DC et al.:
SPG20 protein spartin associates with cardiolipin via its plant-related senescence domain and regulates mitochondrial Ca2+ homeostasis
PLoS ONE
2011
6
|
| 20504295 |
Hooper C et al.:
Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets
BMC Biol.
2010
8: 72
|
| 19765186 |
Milewska M et al.:
Identification of novel spartin-interactors shows spartin is a multifunctional protein
J. Neurochem.
2009
111: 1022-1030
|
| 17332501 |
Bakowska JC et al.:
Troyer syndrome protein spartin is mono-ubiquitinated and functions in EGF receptor trafficking
Mol. Biol. Cell
2007
18: 1683-1692
|
| 19592578 |
Szabo R et al.:
Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice
Development
2009
136: 2653-2663
|
| 30055085 |
Abdelrahman HA et al.:
A recessive truncating variant in thrombospondin-1 domain containing protein 1 gene THSD1 is the underlying cause of nonimmune hydrops fetalis, congenital cardiac defects, and haemangiomas in four patients from a consanguineous family
Am. J. Med. Genet. A
2018
176: 1996-2003
|
| 27895300 |
Santiago-Sim T et al. et al.:
THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage
Stroke
2016
47: 3005-3013
|
| 26036949 |
Shamseldin HE et al. et al.:
Identification of embryonic lethal genes in humans by autozygosity mapping and exome sequencing in consanguineous families
Genome Biol.
2015
16: 116
|
| 26822228 |
Haasdijk RA et al. et al.:
THSD1 preserves vascular integrity and protects against intraplaque haemorrhaging in ApoE-/- mice
Cardiovasc. Res.
2016
110: 129-139
|
| 27307223 |
Edvardson S et al.:
A mutation in the THG1L gene in a family with cerebellar ataxia and developmental delay
Neurogenetics
2016
17: 219-225
|
| 30214071 |
Shaheen R et al. et al.:
Genomic and phenotypic delineation of congenital microcephaly
Genet. Med.
2019
21: 545-552
|
| 15459185 |
Guo D et al.:
Identification and characterization of a novel cytoplasm protein ICF45 that is involved in cell cycle regulation
J. Biol. Chem.
2004
279
|
| 21784897 |
Hickey FB et al.:
IHG-1 promotes mitochondrial biogenesis by stabilizing PGC-1alpha
J. Am. Soc. Nephrol.
2011
22: 1475-1485
|
| 22108047 |
Shan L et al.:
Proteomic analysis of amniotic fluid of pregnant rats with spina bifida aperta
J Proteomics
2012
75: 1181-1189
|
| 19940183 |
Rudrabhatla P et al.:
Peptidyl-prolyl isomerase 1 regulates protein phosphatase 2A-mediated topographic phosphorylation of neurofilament proteins
J Neurosci
2009
29
|
| 30906254 |
Haidar M et al.:
Septal GABA and Glutamate Neurons Express RXFP3 mRNA and Depletion of Septal RXFP3 Impaired Spatial Search Strategy and Long-Term Reference Memory in Adult Mice
Front Neuroanat
2019
13: 30
|
| 2512436 |
Matalon R et al.:
SSIEM Award. Aspartoacylase deficiency: the enzyme defect in Canavan disease
J. Inherit. Metab. Dis.
1989
12: Suppl 2 329-331
|
| 25875846 |
Kyostila K et al. et al.:
A missense change in the ATG4D gene links aberrant autophagy to a neurodegenerative vacuolar storage disease
PLoS Genet.
2015
11
|
| 16767699 |
Blaser S et al.:
Human endothelial cell septins: SEPT11 is an interaction partner of SEPT5
J. Pathol.
2006
210: 103-110
|
| 24606058 |
Musunuri S et al.:
Quantification of the brain proteome in Alzheimers disease using multiplexed mass spectrometry
J. Proteome Res.
2014
13: 2056-2068
|
| 15816977 |
Guerrini R et al.:
Genetic malformations of the cerebral cortex and epilepsy
Epilepsia
2005
46: Suppl 1 32-37
|
| 19846429 |
Vos YJ et al. et al.:
Genotype-phenotype correlations in L1 syndrome: a guide for genetic counselling and mutation analysis
J. Med. Genet.
2010
47: 169-175
|
| 15485489 |
Xue J et al.:
Septin 3 (G-septin) is a developmentally regulated phosphoprotein enriched in presynaptic nerve terminals
J. Neurochem.
2004
91: 579-590
|
| 25721793 |
Chen L et al.:
Endophilin-1 regulates blood-brain barrier permeability via EGFR-JNK signaling pathway
Brain Res.
2015
1606: 44-53
|
| 24979773 |
Boulakirba S et al.:
Arf6 exchange factor EFA6 and endophilin directly interact at the plasma membrane to control clathrin-mediated endocytosis
Proc. Natl. Acad. Sci. U.S.A.
2014
111: 9473-9478
|
| 29274751 |
Moriguchi S et al. et al.:
Reduced expression of Na(+)/Ca(2+) exchangers is associated with cognitive deficits seen in Alzheimers disease model mice
Neuropharmacology
2018
131: 291-303
|
| 29941946 |
Sirabella R et al.:
NCX1 and NCX3 as potential factors contributing to neurodegeneration and neuroinflammation in the A53T transgenic mouse model of Parkinsons Disease
Cell Death Dis
2018
9: 725
|
| 24101730 |
Scorziello A et al. et al.:
NCX3 regulates mitochondrial Ca(2+) handling through the AKAP121-anchored signaling complex and prevents hypoxia-induced neuronal death
J. Cell. Sci.
2013
126: 5566-5577
|
| 24616101 |
Michel LY et al.:
Function and regulation of the Na+-Ca2+ exchanger NCX3 splice variants in brain and skeletal muscle
J. Biol. Chem.
2014
289
|
| 31467276 |
Jadiya P et al.:
Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimers disease
Nat Commun
2019
10: 3885
|
| 23616530 |
Parnis J et al.:
Mitochondrial exchanger NCLX plays a major role in the intracellular Ca2+ signaling, gliotransmission, and proliferation of astrocytes
J. Neurosci.
2013
33: 7206-7219
|
| 31269452 |
Raihan O et al.:
SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE
Cell Rep
2019
28: 78-90.e6
|
| 32127770 |
Abiodun OA et al.:
Role of brain renin angiotensin system in neurodegeneration: An update
Saudi J Biol Sci
2020
27: 905-912
|
| 27252382 |
Napolitano G et al.:
TFEB at a glance
J. Cell. Sci.
2016
129: 2475-2481
|
| 20484629 |
Wan J et al.:
Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimers disease
J. Neurosci.
2010
30: 6873-6881
|
| 23481255 |
Sharifi R et al. et al.:
Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease
EMBO J.
2013
32: 1225-1237
|
| 15057524 |
Kennedy BP et al.:
Elevated S-adenosylhomocysteine in Alzheimer brain: influence on methyltransferases and cognitive function
J Neural Transm (Vienna)
2004
111: 547-567
|
| 28259365 |
Mi Z et al.:
Loss of precuneus dendritic spines immunopositive for spinophilin is related to cognitive impairment in early Alzheimers disease
Neurobiol. Aging
2017
55: 159-166
|
| 21039478 |
Cocco C et al.:
Distribution of VGF peptides in the human cortex and their selective changes in Parkinsons and Alzheimers diseases
J. Anat.
2010
217: 683-693
|
| 28943283 |
Chatterjee M et al.:
STEP inhibition reverses behavioral, electrophysiologic, and synaptic abnormalities in Fmr1 KO mice
Neuropharmacology
2018
128: 43-53
|
| 27265785 |
Neuner SM et al.:
Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimers disease mouse models
Behav. Brain Res.
2017
322: 288-298
|
| 18983893 |
Jiang H et al.:
Association between NR2B subunit gene (GRIN2B) promoter polymorphisms and sporadic Alzheimers disease in the North Chinese population
Neurosci. Lett.
2009
450: 356-360
|
| 32694537 |
Squillario M et al.:
A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimers disease
Sci Rep
2020
10: 12063
|
| 19562769 |
Lee JY et al.:
Association of DRD3 and GRIN2B with impulse control and related behaviors in Parkinsons disease
Mov. Disord.
2009
24: 1803-1810
|
| 25731621 |
Jiang S et al.:
Identification of novel quantitative traits-associated susceptibility loci for APOE epsilon 4 non-carriers of Alzheimers disease
Curr Alzheimer Res
2015
12: 218-227
|
| 29439356 |
Mahady L et al.:
Frontal Cortex Epigenetic Dysregulation During the Progression of Alzheimers Disease
J. Alzheimers Dis.
2018
62: 115-131
|
| 28630030 |
Barbash S et al. et al.:
Alzheimers brains show inter-related changes in RNA and lipid metabolism
Neurobiol. Dis.
2017
106: 1-13
|
| 28100725 |
Chen J et al. et al.:
Genome-wide association study identifies MAPT locus influencing human plasma tau levels
Neurology
2017
88: 669-676
|
| 31951107 |
Sierksma A et al.:
Novel Alzheimer risk genes determine the microglia response to amyloid-beta but not to TAU pathology
EMBO Mol Med
2020
12
|
| 21640374 |
Zwilling D et al. et al.:
Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration
Cell
2011
145: 863-874
|
| 30349106 |
Marzi SJ et al. et al.:
A histone acetylome-wide association study of Alzheimers disease identifies disease-associated H3K27ac differences in the entorhinal cortex
Nat. Neurosci.
2018
21: 1618-1627
|
| 23201485 |
Salani F et al.:
Increased expression of interleukin-18 receptor in blood cells of subjects with mild cognitive impairment and Alzheimers disease
Cytokine
2013
61: 360-363
|
| 31066045 |
Wu K et al.:
Lin28B regulates the fate of grafted mesenchymal stem cells and enhances their protective effects against Alzheimers disease by upregulating IGF-2
J. Cell. Physiol.
2019
234
|
| 28381441 |
Shinohara M et al.:
Role of LRP1 in the pathogenesis of Alzheimers disease: evidence from clinical and preclinical studies
J. Lipid Res.
2017
58: 1267-1281
|
| 16774924 |
Culbert AA et al.:
MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease
J. Biol. Chem.
2006
281
|
| 29391029 |
Jiang S et al. et al.:
Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex
Mol Neurodegener
2018
13: 5
|
| 23295856 |
Rue L et al.:
Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntingtons disease
Neurobiol. Dis.
2013
52: 219-228
|
| 31266021 |
Grimmer T et al.:
Associations of Neprilysin Activity in CSF with Biomarkers for Alzheimers Disease
Neurodegener Dis
2019
19: 43-50
|
| 26394601 |
Saad M et al.:
Family-based genome scan for age at onset of late-onset Alzheimers disease in whole exome sequencing data
Genes Brain Behav.
2015
14: 607-617
|
| 16410748 |
Sheffield LG et al.:
Nuclear pore complex proteins in Alzheimer disease
J. Neuropathol. Exp. Neurol.
2006
65: 45-54
|
| 28466093 |
Gellhaar S et al.:
Myeloperoxidase-immunoreactive cells are significantly increased in brain areas affected by neurodegeneration in Parkinsons and Alzheimers disease
Cell Tissue Res.
2017
369: 445-454
|
| 27589732 |
Bissig C et al.:
PMEL Amyloid Fibril Formation: The Bright Steps of Pigmentation
|
| 23234877 |
Chong MS et al.:
Gene expression profiling of peripheral blood leukocytes shows consistent longitudinal downregulation of TOMM40 and upregulation of KIR2DL5A, PLOD1, and SLC2A8 among fast progressors in early Alzheimers disease
J. Alzheimers Dis.
2013
34: 399-405
|
| 28778446 |
Wang KS et al.:
Family-based association analysis of NAV2 gene with the risk and age at onset of Alzheimers disease
J. Neuroimmunol.
2017
310: 60-65
|
| 18834923 |
Erickson RP et al.:
Variation in NPC1, the gene encoding Niemann-Pick C1, a protein involved in intracellular cholesterol transport, is associated with Alzheimer disease and/or aging in the Polish population
Neurosci. Lett.
2008
447: 153-157
|
| 21444756 |
Trovo L et al.:
Sphingomyelin upregulation in mature neurons contributes to TrkB activity by Rac1 endocytosis
J Cell Sci
2011
124: 1308-1315
|
| 9712180 |
Kramar EA et al.:
Role of nitric oxide in angiotensin IV-induced increases in cerebral blood flow
Regul Pept
1998
74: 185-192
|
| 17900533 |
Grammatopoulos TN et al.:
Angiotensin II protects against alpha-synuclein toxicity and reduces protein aggregation in vitro
Biochem Biophys Res Commun
2007
363: 846-851
|
| 11249971 |
Lee J et al.:
Potentiation of cholinergic transmission in the rat hippocampus by angiotensin IV and LVV-hemorphin-7
Neuropharmacology
2001
40: 618-623
|
| 16101747 |
Stragier B et al.:
In vivo characterization of the angiotensin-(1-7)-induced dopamine and gamma-aminobutyric acid release in the striatum of the rat
Eur J Neurosci
2005
22: 658-664
|
| 9647693 |
Wood JD et al.:
Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins
Mol Cell Neurosci
1998
11: 149-160
|
| 8612237 |
Burke JR et al.:
Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH
Nat Med
1996
2: 347-350
|
| 10332026 |
Okamura-Oho Y et al.:
Dentatorubral-pallidoluysian atrophy protein interacts through a proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate
Hum Mol Genet
1999
8: 947-957
|
| 32375403 |
author information missing
article information missing
|
| 33739454 |
author information missing
article information missing
|
| 31376476 |
author information missing
article information missing
|
| 27158906 |
author information missing
article information missing
|
| 29245901 |
Hu T et al.:
Navbeta2 knockdown improves cognition in APP/PS1 mice by partially inhibiting seizures and APP amyloid processing
Oncotarget
2017
8
|
| 27932425 |
Bao Y et al. et al.:
Scn2b Deletion in Mice Results in Ventricular and Atrial Arrhythmias
|
| 25575679 |
XiYang YB et al. et al.:
Sodium Channel Voltage-Gated Beta 2 Plays a Vital Role in Brain Aging Associated with Synaptic Plasticity and Expression of COX5A and FGF-2
Mol. Neurobiol.
2016
53: 955-967
|
| 15833746 |
Kim DY et al.:
Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration
J. Biol. Chem.
2005
280
|
| 32301221 |
Goren A et al. et al.:
A preliminary observation: male pattern hair loss among hospitalized COVID-19 patients in Spain - A potential clue to the role of androgens in COVID-19 severity
|
| 32318865 |
Zhu H et al.:
Cardiovascular Complications in Patients with COVID-19: Consequences of Viral Toxicities and Host Immune Response
Curr Cardiol Rep
2020
22: 32
|
| 32333398 |
Sriram K et al.:
A hypothesis for pathobiology and treatment of COVID-19: The centrality of ACE1/ACE2 imbalance
Br J Pharmacol
2020
177: 4825-4844
|
| 32333398 |
Sriram K et al.:
A hypothesis for pathobiology and treatment of COVID-19: the centrality of ACE1/ACE2 imbalance
|
| 11880296 |
Papp M et al.:
Angiotensin receptor subtype AT(1) mediates alveolar epithelial cell apoptosis in response to ANG II
Am. J. Physiol. Lung Cell Mol. Physiol.
2002
282: L713-L718
|
| 32341442 |
Kai H et al.:
Interactions of coronaviruses with ACE2, angiotensin II, and RAS inhibitors-lessons from available evidence and insights into COVID-19
|
| 32336612 |
Verdecchia P et al.:
The pivotal link between ACE2 deficiency and SARS-CoV-2 infection
|
| 32015507 |
Zhou P et al. et al.:
A pneumonia outbreak associated with a new coronavirus of probable bat origin
Nature
2020
579: 270-273
|
| 32142651 |
Hoffmann M et al. et al.:
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Cell
2020
181: 271-280.e8
|
| 32155444 |
Walls AC et al.:
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
Cell
2020
181: 281-292.e6
|
| 32171076 |
Zhou F et al. et al.:
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
Lancet
2020
395: 1054-1062
|
| 32048163 |
Liu Y et al. et al.:
Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury
Sci China Life Sci
2020
63: 364-374
|
| 32217834 |
author information missing
SARS-CoV-2: a storm is raging
J. Clin. Invest.
2020
130: 2202-2205
|
| 32265235 |
author information missing
COVID-19 and Kawasaki Disease: Novel Virus and Novel Case
|
| 32264791 |
Gheblawi M et al.:
Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System
|
| 32333836 |
Monteil V et al. et al.:
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
|
| 32249956 |
Hussain M et al.:
Structural variations in human ACE2 may influence its binding with SARS-CoV-2 spike protein
|
| 32133153 |
Cao Y et al.:
Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations
Cell Discov
2020
6: 11
|
| 32286245 |
Henry BM et al.:
Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis
|
| 32504360 |
Sun D et al.:
SARS-CoV-2 infection in infants under 1 year of age in Wuhan City, China
|
| 31986264 |
Huang C et al. et al.:
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Lancet
2020
395: 497-506
|
| 32161940 |
Qin C et al.:
Dysregulation of immune response in patients with COVID-19 in Wuhan, China
|
| 32299776 |
Magro C et al.:
Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases
|
| 32367170 |
Helms J et al. et al.:
High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study
|
| 32302438 |
Panigada M et al.:
Hypercoagulability of COVID-19 patients in Intensive Care Unit. A Report of Thromboelastography Findings and other Parameters of Hemostasis
|
| 32413319 |
Ziegler CGK et al. et al.:
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
Cell
2020
181: 1016-1035.e19
|
| 32432918 |
Stelzig KE et al.:
Estrogen regulates the expression of SARS-CoV-2 receptor ACE2 in differentiated airway epithelial cells
Am. J. Physiol. Lung Cell Mol. Physiol.
2020
318
|
| 32544563 |
Mahmudpour M et al.:
COVID-19 cytokine storm: The anger of inflammation
Cytokine
2020
133
|
| 32325025 |
Hirano T et al.:
COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome
Immunity
2020
52: 731-733
|
| 32408336 |
Bojkova D et al.:
Proteomics of SARS-CoV-2-infected host cells reveals therapy targets
|
| 32613681 |
Rhodes JM et al.:
Perspective: Vitamin D deficiency and COVID-19 severity - plausibly linked by latitude, ethnicity, impacts on cytokines, ACE2, and thrombosis (R1)
|
| 32340551 |
Elfiky AA et al.:
Natural products may interfere with SARS-CoV-2 attachment to the host cell
|
| 32558485 |
Ellinghaus D et al. et al.:
Genomewide Association Study of Severe Covid-19 with Respiratory Failure
|
| 32169481 |
Ibrahim IM et al.:
COVID-19 spike-host cell receptor GRP78 binding site prediction
J. Infect.
2020
80: 554-562
|
| 32432657 |
Bunyavanich S et al.:
Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults
|
| 32356627 |
Mancia G et al.:
Renin-Angiotensin-Aldosterone System Blockers and the Risk of Covid-19
N. Engl. J. Med.
2020
382: 2431-2440
|
| 32356628 |
Reynolds HR et al. et al.:
Renin-Angiotensin-Aldosterone System Inhibitors and Risk of Covid-19
N. Engl. J. Med.
2020
382: 2441-2448
|
| 32271368 |
Lighter J et al.:
Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission
|
| 32271993 |
Simonnet A et al.:
High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Requiring Invasive Mechanical Ventilation
Obesity (Silver Spring)
2020
28: 1195-1199
|
| 32444366 |
Petrilli CM et al.:
Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study
BMJ
2020
369: m1966
|
| 32228222 |
Meng J et al. et al.:
Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension
Emerg Microbes Infect
2020
9: 757-760
|
| 32266828 |
Lippi G et al.:
Electrolyte imbalances in patients with severe coronavirus disease 2019 (COVID-19)
Ann. Clin. Biochem.
2020
57: 262-265
|
| 32525548 |
Chen D et al.:
Assessment of Hypokalemia and Clinical Characteristics in Patients With Coronavirus Disease 2019 in Wenzhou, China
JAMA Netw Open
2020
3
|
| 32075877 |
Wrapp D et al.:
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Science
2020
367: 1260-1263
|
| 32225175 |
Shang J et al.:
Structural basis of receptor recognition by SARS-CoV-2
Nature
2020
581: 221-224
|
| 32676594 |
author information missing
Unique transcriptional changes in coagulation cascade genes in SARS-CoV-2-infected lung epithelial cells: A potential factor in COVID-19 coagulopathies
|
| 32306492 |
Zhang L et al.:
D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19
J Thromb Haemost
2020
18: 1324-1329
|
| 2117226 |
Sokol PA et al.:
Cloning and expression of the Pseudomonas aeruginosa exoenzyme S toxin gene
Microb Pathog
1990
8: 243-257
|
| 33119703 |
Jin X et al.:
The values of coagulation function in COVID-19 patients
PLoS One
2020
15
|
| 32525813 |
Hrenak J et al.:
Renin-angiotensin system and SARS-CoV-2 interaction: underlying mechanisms and potential clinical implications
Gen Physiol Biophys
2020
39: 203-204
|
| 32642005 |
Datta PK et al.:
SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy
Theranostics
2020
10: 7448-7464
|
| 12021572 |
Mehta JL et al.:
Angiotensin II and IV stimulate expression and release of plasminogen activator inhibitor-1 in cultured human coronary artery endothelial cells
J Cardiovasc Pharmacol
2002
39: 789-794
|
| 33486116 |
Vitiello A et al.:
Drugs acting on the renin-angiotensin system and SARS-CoV-2
|
| 33530357 |
Yu Y et al.:
Alzheimers and Parkinsons Diseases Predict Different COVID-19 Outcomes: A UK Biobank Study
|
| 32437244 |
Gargaglioni LH et al.:
Lets talk about sex in the context of COVID-19
J Appl Physiol (
1985
: 2020 128 1533-1538
|
| 32497323 |
Zhuang MW et al.:
Increasing host cellular receptor-angiotensin-converting enzyme 2 expression by coronavirus may facilitate 2019-nCoV (or SARS-CoV-2) infection
J Med Virol
2020
92: 2693-2701
|
| 32669955 |
Wang Y et al.:
A comprehensive investigation of the mRNA and protein level of ACE2, the putative receptor of SARS-CoV-2, in human tissues and blood cells
Int J Med Sci
2020
17: 1522-1531
|
| 33455043 |
Wark PAB et al. et al.:
ACE2 expression is elevated in airway epithelial cells from older and male healthy individuals but reduced in asthma
|
| 33169633 |
Cure E et al.:
Angiotensin II, III, and IV may be important in the progression of COVID-19
J Renin Angiotensin Aldosterone Syst
2020
21
|
| 32503680 |
Wu Z et al.:
Elevation of plasma angiotensin II level is a potential pathogenesis for the critically ill COVID-19 patients
Crit Care
2020
24: 290
|
| 32446312 |
Luo P et al.:
Metformin Treatment Was Associated with Decreased Mortality in COVID-19 Patients with Diabetes in a Retrospective Analysis
Am J Trop Med Hyg
2020
103: 69-72
|
| 33471718 |
Li J et al. et al.:
Metformin Use in Diabetes Prior to Hospitalization: Effects on Mortality in Covid-19
Endocr Pract
2020
26: 1166-1172
|
| 32264791 |
Gheblawi M et al.:
Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System: Celebrating the 20th Anniversary of the Discovery of ACE2
Circ Res
2020
126: 1456-1474
|
| 32474043 |
Pirola CJ et al.:
Estimation of Renin-Angiotensin-Aldosterone-System (RAAS)-Inhibitor effect on COVID-19 outcome: A Meta-analysis
J Infect
2020
81: 276-281
|
| 33583366 |
Lanza K et al.:
Renin Angiotensin System in Central Nervous System diseases and its interaction with COVID-19
|
| 33117379 |
Zipeto D et al.:
ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19
Front Immunol
2020
11
|
| 32651579 |
Gupta A et al. et al.:
Extrapulmonary manifestations of COVID-19
Nat Med
2020
26: 1017-1032
|
| 33426683 |
Rahman MM et al.:
Potential detrimental role of soluble ACE2 in severe COVID-19 comorbid patients
|
| 33042994 |
Costa LB et al.:
Insights on SARS-CoV-2 Molecular Interactions With the Renin-Angiotensin System
Front Cell Dev Biol
2020
8
|
| 32558877 |
Fosbol EL et al.:
Association of Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker Use With COVID-19 Diagnosis and Mortality
JAMA
2020
324: 168-177
|
| 32485082 |
Bean DM et al. et al.:
Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers are not associated with severe COVID-19 infection in a multi-site UK acute hospital trust
Eur J Heart Fail
2020
22: 967-974
|
| 32139904 |
Zheng YY et al.:
COVID-19 and the cardiovascular system
Nat Rev Cardiol
2020
17: 259-260
|
| 32302265 |
Zhang P et al. et al.:
Association of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With Hypertension Hospitalized With COVID-19
Circ Res
2020
126: 1671-1681
|
| 32442562 |
Zuo T et al. et al.:
Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization
Gastroenterology
2020
159: 944-955.e8
|
| 32942285 |
Benton DJ et al.:
Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion
Nature
2020
588: 327-330
|
| 32142773 |
Xiao F et al.:
Evidence for Gastrointestinal Infection of SARS-CoV-2
Gastroenterology
2020
158: 1831-1833.e3
|
| 32312790 |
Effenberger M et al. et al.:
Faecal calprotectin indicates intestinal inflammation in COVID-19
Gut
2020
69: 1543-1544
|
| 32437749 |
Wang C et al.:
Human Intestinal Defensin 5 Inhibits SARS-CoV-2 Invasion by Cloaking ACE2
Gastroenterology
2020
159: 1145-1147.e4
|
| 32208987 |
Danser AHJ et al.:
Renin-Angiotensin System Blockers and the COVID-19 Pandemic: At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers
Hypertension
2020
75: 1382-1385
|
| 33539316 |
Kutz A et al.:
Renin-angiotensin-aldosterone system peptide profiles in patients with COVID-19
Eur J Endocrinol
2021
184: 543-552
|
| 32219357 |
Inciardi RM et al. et al.:
Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19)
JAMA Cardiol
2020
5: 819-824
|
| 32211816 |
Shi S et al. et al.:
Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China
JAMA Cardiol
2020
5: 802-810
|
| 32358202 |
Lamers MM et al. et al.:
SARS-CoV-2 productively infects human gut enterocytes
Science
2020
369: 50-54
|
| 33544293 |
Laurentius A et al.:
Clinical outcome of renin-angiotensin-aldosterone system blockers in treatment of hypertensive patients with COVID-19: a systematic review and meta-analysis
Egypt Heart J
2021
73: 13
|
| 33614688 |
Maric I et al.:
Decreased Mortality Rate Among COVID-19 Patients Prescribed Statins: Data From Electronic Health Records in the US
Front Med (Lausanne)
2021
8
|
| 32592657 |
Zhang XJ et al. et al.:
In-Hospital Use of Statins Is Associated with a Reduced Risk of Mortality among Individuals with COVID-19
Cell Metab
2020
32: 176-187.e4
|
| 32674818 |
De Spiegeleer A et al. et al.:
The Effects of ARBs, ACEis, and Statins on Clinical Outcomes of COVID-19 Infection Among Nursing Home Residents
J Am Med Dir Assoc
2020
21: 909-914.e2
|
| 32882643 |
Hariyanto TI et al.:
Statin therapy did not improve the in-hospital outcome of coronavirus disease 2019 (COVID-19) infection
Diabetes Metab Syndr
2020
14: 1613-1615
|
| 33091555 |
Cariou B et al. et al.:
Routine use of statins and increased COVID-19 related mortality in inpatients with type 2 diabetes: Results from the CORONADO study
Diabetes Metab
2021
47
|
| 32708430 |
Fakhouri EW et al.:
Genetic Polymorphisms Complicate COVID-19 Therapy: Pivotal Role of HO-1 in Cytokine Storm
|
| 33667433 |
Chacko SR et al. et al.:
Association of pre-admission statin use with reduced in-hospital mortality in COVID-19
|
| 33506050 |
Khalili S et al.:
Prevalence, Risk Factors and Outcomes Associated with Acute Kidney Injury in Patients Hospitalized for COVID-19: A Comparative Study between Diabetic and Nondiabetic Patients
J Diabetes Res
2021
2021
|
| 33330541 |
Fan Y et al. et al.:
Association of Statin Use With the In-Hospital Outcomes of 2019-Coronavirus Disease Patients: A Retrospective Study
Front Med (Lausanne)
2020
7
|
| 33092446 |
Saeed O et al. et al.:
Statin Use and In-Hospital Mortality in Patients With Diabetes Mellitus and COVID-19
J Am Heart Assoc
2020
9
|
| 33718779 |
Gupta A et al.:
Diabetes Mellitus and Hypertension Increase Risk of Death in Novel Corona Virus Patients Irrespective of Age: a Prospective Observational Study of Co-morbidities and COVID-19 from India
|
| 33418230 |
Katz J et al.:
Increased risk for COVID-19 in patients with vitamin D deficiency
Nutrition
2021
84
|
| 32745239 |
San Juan I et al. et al.:
Abnormal concentration of porphyrins in serum from COVID-19 patients
Br J Haematol
2020
190: e265-e267
|
| 33176981 |
Su WL et al.:
Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1
J Microbiol Immunol Infect
2021
54: 113-116
|
| 33747093 |
Heidarpour M et al.:
Rhabdomyolysis plus Hypocalcemia and Diabetic Ketoacidosis as Concurrent Rare COVID-19 Manifestations
Case Rep Med
2021
2021
|
| 32622796 |
Liu J et al.:
Prevalence and predictive value of hypocalcemia in severe COVID-19 patients
J Infect Public Health
2020
13: 1224-1228
|
| 32615280 |
Goldman N et al.:
High prevalence of COVID-19-associated diabetic ketoacidosis in UK secondary care
Diabetes Res Clin Pract
2020
166
|
| 33575135 |
Haroun MW et al.:
Rhabdomyolysis in COVID-19 Patients: A Retrospective Observational Study
Cureus
2021
13
|
| 32712122 |
Liu SP et al.:
Hyperglycemia is a strong predictor of poor prognosis in COVID-19
Diabetes Res Clin Pract
2020
167
|
| 32697943 |
Codo AC et al. et al.:
Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1alpha/Glycolysis-Dependent Axis
Cell Metab
2020
32: 437-446.e5
|
| 32726128 |
Chanana N et al.:
Sex-derived attributes contributing to SARS-CoV-2 mortality
Am J Physiol Endocrinol Metab
2020
319: E562-E567
|
| 32928868 |
Dambha-Miller H et al.:
Currently prescribed drugs in the UK that could upregulate or downregulate ACE2 in COVID-19 disease: a systematic review
BMJ Open
2020
10
|
| 33833480 |
Alberca GGF et al.:
Coronavirus disease-2019 and the intestinal tract: An overview
World J Gastroenterol
2021
27: 1255-1266
|
| 33084795 |
Amaral LTW et al.:
Abdominal symptoms as initial manifestation of COVID-19: a case series
Einstein (Sao Paulo)
2020
18: eRC5831
|
| 32222992 |
Zhang T et al.:
Detectable SARS-CoV-2 viral RNA in feces of three children during recovery period of COVID-19 pneumonia
J Med Virol
2020
92: 909-914
|
| 33591607 |
Marasco G et al.:
Implications of SARS-CoV-2 infection for neurogastroenterology
Neurogastroenterol Motil
2021
33
|
| 32646736 |
Uzzan M et al.:
Patients with COVID-19 present with low plasma citrulline concentrations that associate with systemic inflammation and gastrointestinal symptoms
Dig Liver Dis
2020
52: 1104-1105
|
| 33122999 |
Deffner F et al.:
Histological Evidence for the Enteric Nervous System and the Choroid Plexus as Alternative Routes of Neuroinvasion by SARS-CoV2
Front Neuroanat
2020
14
|
| 32895611 |
Mattone E et al.:
Acute acalculous cholecystitis on a COVID-19 patient: a case report
Ann Med Surg (Lond)
2020
58: 73-75
|
| 32571224 |
Ying M et al.:
COVID-19 with acute cholecystitis: a case report
BMC Infect Dis
2020
20: 437
|
| 32890595 |
Balaphas A et al.:
COVID-19 can mimic acute cholecystitis and is associated with the presence of viral RNA in the gallbladder wall
J Hepatol
2020
73: 1566-1568
|
| 32900752 |
Kumaran NK et al.:
Coronavirus disease-19 (COVID-19) associated with acute necrotising pancreatitis (ANP)
|
| 32764201 |
Barlass U et al.:
Marked Elevation of Lipase in COVID-19 Disease: A Cohort Study
Clin Transl Gastroenterol
2020
11
|
| 32247022 |
Wang F et al.:
Pancreatic Injury Patterns in Patients With Coronavirus Disease 19 Pneumonia
Gastroenterology
2020
159: 367-370
|
| 32339257 |
Anand ER et al.:
Acute pancreatitis in a COVID-19 patient
Br J Surg
2020
107: e182
|
| 32311512 |
Wei XS et al.:
Diarrhea Is Associated With Prolonged Symptoms and Viral Carriage in Corona Virus Disease 2019
Clin Gastroenterol Hepatol
2020
18: 1753-1759.e2
|
| 32690600 |
Zuo T et al.:
Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19
Gut
2021
70: 276-284
|
| 34272374 |
author information missing
article information missing
|
| 33422806 |
author information missing
article information missing
|
| 32277967 |
author information missing
article information missing
|
| 34528721 |
author information missing
article information missing
|
| 33060197 |
author information missing
article information missing
|
| 32728199 |
author information missing
article information missing
|
| 37528621 |
author information missing
article information missing
|
| 29998156 |
Honorat JA et al.:
Autoimmune septin-5 cerebellar ataxia
Neurol Neuroimmunol Neuroinflamm
2018
5: e474
|
| 26035387 |
Wang JY et al.:
Sun1 deficiency leads to cerebellar ataxia in mice
Dis Model Mech
2015
8: 957-967
|
| 19240081 |
Suzuki G et al.:
Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice
Hum. Mol. Genet.
2009
18: 1652-1660
|
| 14647384 |
Li W et al.:
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
Nature
2003
426: 450-454
|
| 16007097 |
Kuba K et al. et al.:
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury
Nat. Med.
2005
11: 875-879
|
| 15496474 |
Jeffers SA et al. et al.:
CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus
Proc. Natl. Acad. Sci. U.S.A.
2004
101
|
| 15381116 |
Itoyama S et al. et al.:
ACE1 polymorphism and progression of SARS
Biochem. Biophys. Res. Commun.
2004
323: 1124-1129
|
| 15819995 |
Chan KC et al. et al.:
Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control study
BMC Infect. Dis.
2005
5: 26
|
| 19411314 |
Jia HP et al.:
Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia
Am. J. Physiol. Lung Cell Mol. Physiol.
2009
297: L84-L96
|
| 18490652 |
Haga S et al.:
Modulation of TNF-alpha-converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-alpha production and facilitates viral entry
Proc Natl Acad Sci U S A
2008
105: 7809-7814
|
| 19864379 |
Glowacka I et al. et al.:
Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63
J. Virol.
2010
84: 1198-1205
|
| 18070603 |
Lambert DW et al.:
Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain
FEBS Lett.
2008
582: 385-390
|
| 16339146 |
Huang IC et al. et al.:
SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells
J. Biol. Chem.
2006
281: 3198-3203
|
| 19333547 |
Yang JK et al.:
Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes
Acta Diabetol
2010
47: 193-199
|
| 18818423 |
Guillon P et al.:
Inhibition of the interaction between the SARS-CoV spike protein and its cellular receptor by anti-histo-blood group antibodies
Glycobiology
2008
18: 1085-1093
|
| 16940539 |
Chan CP et al.:
Modulation of the unfolded protein response by the severe acute respiratory syndrome coronavirus spike protein
J. Virol.
2006
80: 9279-9287
|
| 17037581 |
Jia HP et al.:
Infection of human airway epithelia by SARS coronavirus is associated with ACE2 expression and localization
Adv. Exp. Med. Biol.
2006
581: 479-484
|
| 15983030 |
Lambert DW et al.:
Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2)
J. Biol. Chem.
2005
280
|
| 19453650 |
Oudit GY et al.:
SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS
Eur J Clin Invest
2009
39: 618-625
|
| 23962453 |
Perlot T et al.:
ACE2 - from the renin-angiotensin system to gut microbiota and malnutrition
Microbes Infect
2013
15: 866-873
|
| 20212457 |
Turato C et al.:
SERPINB3 modulates TGF-beta expression in chronic liver disease
Lab. Invest.
2010
90: 1016-1023
|
| 8362987 |
Mars WM et al.:
Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA
Am J Pathol
1993
143: 949-958
|
| 23354406 |
Villano G et al.:
Increased Th1 immune response in SERPINB3 transgenic mice during acute liver failure
Exp. Biol. Med. (Maywood)
2012
237: 1474-1482
|
| 22333924 |
Marseglia G et al.:
372 kb microdeletion in 18q12.3 causing SETBP1 haploinsufficiency associated with mild mental retardation and expressive speech impairment
Eur J Med Genet
2012
55: 216-221
|
| 21037274 |
Filges I et al.:
Reduced expression by SETBP1 haploinsufficiency causes developmental and expressive language delay indicating a phenotype distinct from Schinzel-Giedion syndrome
J. Med. Genet.
2011
48: 117-122
|
| 20436468 |
Hoischen A et al. et al.:
De novo mutations of SETBP1 cause Schinzel-Giedion syndrome
Nat. Genet.
2010
42: 483-485
|
| 29666323 |
Liu WL et al.:
Schinzel-Giedion syndrome: a novel case, review and revised diagnostic criteria
J. Genet.
2018
97: 35-46
|
| 9141561 |
Warren-Perry MG et al.:
A novel point mutation in the insulin gene giving rise to hyperproinsulinemia
J. Clin. Endocrinol. Metab.
1997
82: 1629-1631
|
| 28753426 |
Chen K et al.:
Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity
Cell
2017
170: 492-506.e14
|
| 31527793 |
Diep J et al. et al.:
Enterovirus pathogenesis requires the host methyltransferase SETD3
Nat Microbiol
2019
4: 2523-2537
|
| 21931631 |
Goncalves A et al. et al.:
Functional dissection of the TBK1 molecular network
PLoS ONE
2011
6
|
| 26775243 |
Olmos Y et al.:
The ESCRT machinery: new roles at new holes
Curr. Opin. Cell Biol.
2016
38: 1-11
|
| 20653365 |
Hurley JH et al.:
The ESCRT complexes
Crit. Rev. Biochem. Mol. Biol.
2010
45: 463-487
|
| 31391232 |
Ran Y et al.:
YIPF5 Is Essential for Innate Immunity to DNA Virus and Facilitates COPII-Dependent STING Trafficking
J. Immunol.
2019
203: 1560-1570
|
| 31341044 |
Ahn N et al.:
The Interferon-Inducible Proteoglycan Testican-2/SPOCK2 Functions as a Protective Barrier against Virus Infection of Lung Epithelial Cells
|
| 24156700 |
Zhang F et al.:
DC-SIGN, DC-SIGNR and LSECtin: C-type lectins for infection
Int Rev Immunol
2014
33: 54-66
|
| 31386698 |
Madigan VJ et al.:
Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription
PLoS Pathog
2019
15
|
| 24675744 |
author information missing
article information missing
|
| 21673190 |
author information missing
article information missing
|
| 28537258 |
author information missing
article information missing
|
| 26244546 |
author information missing
article information missing
|
| 19524513 |
author information missing
article information missing
|
| 24244674 |
author information missing
article information missing
|
| 20680033 |
author information missing
article information missing
|
| 25609812 |
author information missing
article information missing
|
| 20628368 |
author information missing
article information missing
|
| 23486063 |
author information missing
article information missing
|
| 11274051 |
Fleming MD et al.:
A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice
Genes Dev.
2001
15: 652-657
|
| 26384929 |
Hardies K et al. et al.:
Recessive mutations in SLC13A5 result in a loss of citrate transport and cause neonatal epilepsy, developmental delay and teeth hypoplasia
Brain
2015
138: 3238-3250
|
| 27600704 |
Schossig A et al. et al.:
SLC13A5 is the second gene associated with Kohlschutter-Tonz syndrome
J. Med. Genet.
2017
54: 54-62
|
| 24995870 |
Thevenon J et al. et al.:
Mutations in SLC13A5 cause autosomal-recessive epileptic encephalopathy with seizure onset in the first days of life
Am. J. Hum. Genet.
2014
95: 113-120
|
| 28406943 |
Irizarry AR et al.:
Defective enamel and bone development in sodium-dependent citrate transporter (NaCT) Slc13a5 deficient mice
PLoS ONE
2017
12
|
| 28264506 |
Bhutia YD et al.:
Plasma Membrane Na(+)-Coupled Citrate Transporter (SLC13A5) and Neonatal Epileptic Encephalopathy
|
| 26870663 |
Chaouch A et al. et al.:
Mutations in the Mitochondrial Citrate Carrier SLC25A1 are Associated with Impaired Neuromuscular Transmission
J Neuromuscul Dis
2014
1: 75-90
|
| 31527857 |
Balaraju S et al. et al.:
Congenital myasthenic syndrome with mild intellectual disability caused by a recurrent SLC25A1 variant
Eur. J. Hum. Genet.
2020
28: 373-377
|
| 31855247 |
Fagerberg CR et al. et al.:
Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration
Brain
2020
143: 94-111
|
| 29659949 |
Zhou Y et al. et al.:
EMC10 governs male fertility via maintaining sperm ion balance
J Mol Cell Biol
2018
10: 503-514
|
| 21490620 |
Marenholz I et al.:
Association screening in the Epidermal Differentiation Complex (EDC) identifies an SPRR3 repeat number variant as a risk factor for eczema
J. Invest. Dermatol.
2011
131: 1644-1649
|
| 29770357 |
Meng X et al.:
MAPK Pathway Involved in Epidermal Terminal Differentiation of Normal Human Epidermal Keratinocytes
Open Med (Wars)
2018
13: 189-195
|
| 22734004 |
Marshall JL et al.:
Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration
J. Cell Biol.
2012
197: 1009-1027
|
| 29887526 |
Chu H et al. et al.:
Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells
J. Biol. Chem.
2018
293
|
| 19526370 |
Ostergaard E et al.:
A novel missense mutation in SUCLG1 associated with mitochondrial DNA depletion, encephalomyopathic form, with methylmalonic aciduria
Eur. J. Pediatr.
2010
169: 201-205
|
| 26475597 |
Carrozzo R et al. et al.:
Succinate-CoA ligase deficiency due to mutations in SUCLA2 and SUCLG1: phenotype and genotype correlations in 71 patients
J. Inherit. Metab. Dis.
2016
39: 243-252
|
| 15016762 |
Fossdal R et al.:
A novel TEAD1 mutation is the causative allele in Sveinssons chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration)
Hum. Mol. Genet.
2004
13: 975-981
|
| 28275260 |
Croft M et al.:
Beyond TNF: TNF superfamily cytokines as targets for the treatment of rheumatic diseases
Nat Rev Rheumatol
2017
13: 217-233
|
| 30289604 |
Blaesius K et al.:
Mutations in the tRNA methyltransferase 1 gene TRMT1 cause congenital microcephaly, isolated inferior vermian hypoplasia and cystic leukomalacia in addition to intellectual disability
Am. J. Med. Genet. A
2018
176: 2517-2521
|
| 28784718 |
Dewe JM et al.:
TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival
|
| 17088085 |
Minegishi Y et al. et al.:
Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity
Immunity
2006
25: 745-755
|
| 20953171 |
Nakagawa K et al.:
Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme
Nature
2010
468: 117-121
|
| 17962451 |
Weiss JS et al. et al.:
Mutations in the UBIAD1 gene on chromosome short arm 1, region 36, cause Schnyder crystalline corneal dystrophy
Invest. Ophthalmol. Vis. Sci.
2007
48: 5007-5012
|
| 30785396 |
Jo Y et al.:
Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice
|
| 25127365 |
Nakagawa K et al.:
Vitamin K2 biosynthetic enzyme, UBIAD1 is essential for embryonic development of mice
PLoS ONE
2014
9
|
| 25805752 |
Manjurano A et al.:
USP38, FREM3, SDC1, DDC, and LOC727982 Gene Polymorphisms and Differential Susceptibility to Severe Malaria in Tanzania
J. Infect. Dis.
2015
212: 1129-1139
|
| 28369220 |
Tsai PC et al. et al.:
A recurrent WARS mutation is a novel cause of autosomal dominant distal hereditary motor neuropathy
Brain
2017
140: 1252-1266
|
| 31036918 |
Khan K et al. et al.:
Recessive variants in ZNF142 cause a complex neurodevelopmental disorder with intellectual disability, speech impairment, seizures, and dystonia
Genet. Med.
2019
21: 2532-2542
|
| 30961659 |
Schulze KV et al. et al.:
Novel parent-of-origin-specific differentially methylated loci on chromosome 16
Clin Epigenetics
2019
11: 60
|
| 31509299 |
Zhang Z et al.:
RNF144B inhibits LPS-induced inflammatory responses via binding TBK1
J. Leukoc. Biol.
2019
106: 1303-1311
|
| 27171064 |
Pastore N et al.:
TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages
Autophagy
2016
12: 1240-1258
|
| 32655027 |
Hassanvand Amouzadeh M et al.:
Proteinuria in Two Sisters with Beaulieu-Boycott-Innes Syndrome, A Case Report
Iran J Kidney Dis
2020
14: 312-314
|
| 31421288 |
Gupta N et al.:
First report of THOC6 related intellectual disability (Beaulieu Boycott Innes syndrome) in two siblings from India
Eur J Med Genet
2020
63
|
| 30476144 |
Mattioli F et al.:
Clinical and functional characterization of recurrent missense variants implicated in THOC6-related intellectual disability
Hum Mol Genet
2019
28: 952-960
|
| 16465618 |
Sass JO et al. et al.:
Mutations in ACY1, the gene encoding aminoacylase 1, cause a novel inborn error of metabolism
Am J Hum Genet
2006
78: 401-409
|
| 28942965 |
Feichtinger RG et al. et al.:
Biallelic C1QBP Mutations Cause Severe Neonatal-, Childhood-, or Later-Onset Cardiomyopathy Associated with Combined Respiratory-Chain Deficiencies
Am J Hum Genet
2017
101: 525-538
|
| 33292863 |
Nkonge KM et al.:
The epidemiology, molecular pathogenesis, diagnosis, and treatment of maturity-onset diabetes of the young (MODY)
Clin Diabetes Endocrinol
2020
6: 20
|
| 31595705 |
de Santana LS et al. et al.:
Targeted sequencing identifies novel variants in common and rare MODY genes
Mol Genet Genomic Med
2019
7: e962
|
| 33477506 |
Ivanoshchuk DE et al.:
The Mutation Spectrum of Maturity Onset Diabetes of the Young (MODY)-Associated Genes among Western Siberia Patients
|
| 25041077 |
Chapla A et al.:
Maturity onset diabetes of the young in India - a distinctive mutation pattern identified through targeted next-generation sequencing
Clin Endocrinol (Oxf)
2015
82: 533-542
|
| 33324081 |
Bouldjennet F et al. et al.:
Maturity-Onset Diabetes of the Young Identified Among Algerian Probands with Early-Onset Diabetes
Diabetes Metab Syndr Obes
2020
13: 4829-4837
|
| 30481753 |
Ozsu E et al.:
Maturity Onset Diabetes of the Young due to Glucokinase, HNF1-A, HNF1-B, and HNF4-A Mutations in a Cohort of Turkish Children Diagnosed as Type 1 Diabetes Mellitus
Horm Res Paediatr
2018
90: 257-265
|
| 33363396 |
Matsha TE et al.:
Incidence of HNF1A and GCK MODY Variants in a South African Population
Appl Clin Genet
2020
13: 209-219
|
| 24100303 |
Pedersen KB et al.:
The transcription factor HNF1alpha induces expression of angiotensin-converting enzyme 2 (ACE2) in pancreatic islets from evolutionarily conserved promoter motifs
Biochim Biophys Acta
2013
1829: 1225-1235
|
| 27223594 |
Carmody D et al.:
Patients with KCNJ11-related diabetes frequently have neuropsychological impairments compared with sibling controls
Diabet Med
2016
33: 1380-1386
|
| 21989597 |
Bowman P et al.:
Heterozygous ABCC8 mutations are a cause of MODY
Diabetologia
2012
55: 123-127
|
| 33013711 |
Lin L et al.:
ABCC8-Related Maturity-Onset Diabetes of the Young (MODY12): A Report of a Chinese Family
Front Endocrinol (Lausanne)
2020
11: 645
|
| 15356046 |
Magge SN et al.:
Familial leucine-sensitive hypoglycemia of infancy due to a dominant mutation of the beta-cell sulfonylurea receptor
J Clin Endocrinol Metab
2004
89: 4450-4456
|
| 16885549 |
Babenko AP et al.:
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus
N Engl J Med
2006
355: 456-466
|
| 22235272 |
Garin I et al.:
Permanent neonatal diabetes caused by creation of an ectopic splice site within the INS gene
PLoS One
2012
7
|
| 9313763 |
Yamada S et al.:
Identification of mutations in the hepatocyte nuclear factor (HNF)-1 alpha gene in Japanese subjects with IDDM
Diabetes
1997
46: 1643-1647
|
| 21730260 |
author information missing
article information missing
|
| 9435328 |
Glaser B et al.:
Familial hyperinsulinism caused by an activating glucokinase mutation
N Engl J Med
1998
338: 226-230
|
| 15277402 |
Cuesta-Munoz AL et al.:
Severe persistent hyperinsulinemic hypoglycemia due to a de novo glucokinase mutation
Diabetes
2004
53: 2164-2168
|
| 15286787 |
Kleta R et al. et al.:
Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorder
Nat Genet
2004
36: 999-1002
|
| 19185582 |
Camargo SM et al.:
Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations
Gastroenterology
2009
136: 872-882
|
| 24452037 |
Bjorkman E et al.:
Angiotensin IV and the human esophageal mucosa: An exploratory study in healthy subjects and gastroesophageal reflux disease patients
J Renin Angiotensin Aldosterone Syst
2015
16: 570-577
|
| 11343641 |
Price ER et al.:
Sensorineural deafness and pigmentation genes: melanocytes and the Mitf transcriptional network
Neuron
2001
30: 15-18
|
| 19363479 |
Mencia A et al.:
Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss
Nat Genet
2009
41: 609-613
|
| 19363478 |
Lewis MA et al. et al.:
An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice
Nat Genet
2009
41: 614-618
|
| 33643381 |
Chiereghin C et al.:
SLC22A4 Gene in Hereditary Non-syndromic Hearing Loss: Recurrence and Incomplete Penetrance of the p.C113Y Mutation in Northwest Africa
Front Genet
2021
12
|
| 11583388 |
Itou M et al.:
Effects of neuropeptide Y on cochlear blood flow in guinea pigs
Acta Otolaryngol
2001
121: 573-578
|
| 22241630 |
Gonzalez-Puebla E et al.:
Altered expressions of MMP-2, MMP-9, and TIMP-2 in placentas from women exposed to lead
Hum Exp Toxicol
2012
31: 662-670
|
| 24832530 |
Fitzpatrick EM et al.:
Examination of characteristics and management of children with hearing loss and autism spectrum disorders
Int J Audiol
2014
53: 577-586
|
| 27023905 |
Ben Said M et al. et al.:
A mutation in SLC22A4 encoding an organic cation transporter expressed in the cochlea strial endothelium causes human recessive non-syndromic hearing loss DFNB60
Hum Genet
2016
135: 513-524
|
| 19229719 |
Gomide VC et al.:
Neuropeptide Y in rat spiral ganglion neurons and inner hair cells of organ of corti and effects of a nontraumatic acoustic stimulation
Int J Neurosci
2009
119: 508-530
|
| 24462371 |
Williamson KA et al. et al.:
Heterozygous loss-of-function mutations in YAP1 cause both isolated and syndromic optic fissure closure defects
Am J Hum Genet
2014
94: 295-302
|
| 11251216 |
Takahashi K et al.:
Caspase-3-deficiency induces hyperplasia of supporting cells and degeneration of sensory cells resulting in the hearing loss
Brain Res
2001
894: 359-367
|
| 32419976 |
Wu X et al.:
Role of microRNA in inner ear stem cells and related research progress
Am J Stem Cells
2020
9: 16-24
|
| 28224282 |
Mahmoudian-Sani MR et al.:
MicroRNAs: effective elements in ear-related diseases and hearing loss
Eur Arch Otorhinolaryngol
2017
274: 2373-2380
|
| 24942165 |
Rudnicki A et al.:
Next-generation sequencing of small RNAs from inner ear sensory epithelium identifies microRNAs and defines regulatory pathways
BMC Genomics
2014
15: 484
|
| 32482884 |
Gnedeva K et al. et al.:
Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal
Proc Natl Acad Sci U S A
2020
117
|
| 23835945 |
Gittelman JX et al.:
Dopamine modulates auditory responses in the inferior colliculus in a heterogeneous manner
J Assoc Res Otolaryngol
2013
14: 719-729
|
| 23548730 |
Munnamalai V et al.:
Wnt signaling during cochlear development
Semin Cell Dev Biol
2013
24: 480-489
|
| 11764294 |
Tachibana M et al.:
Cochlear melanocytes and MITF signaling
J Investig Dermatol Symp Proc
2001
6: 95-98
|
| 32937936 |
Bozanic Urbancic N et al.:
The Importance of Early Genetic Diagnostics of Hearing Loss in Children
|
| 29381991 |
Li Q et al.:
RNA sequencing uncovers the key microRNAs potentially contributing to sudden sensorineural hearing loss
Medicine (Baltimore)
2017
96: e8837
|
| 2371541 |
Barrenas ML et al.:
The influence of inner ear melanin on susceptibility to TTS in humans
Scand Audiol
1990
19: 97-102
|
| 20461409 |
Ishiyama G et al.:
Immunohistochemical localization and mRNA expression of aquaporins in the macula utriculi of patients with Menieres disease and acoustic neuroma
Cell Tissue Res
2010
340: 407-419
|
| 23423560 |
Tong M et al.:
Regenerated synapses between postnatal hair cells and auditory neurons
J Assoc Res Otolaryngol
2013
14: 321-329
|
| 24682784 |
Carpinelli MR et al.:
A new mouse model of Canavan leukodystrophy displays hearing impairment due to central nervous system dysmyelination
Dis Model Mech
2014
7: 649-657
|
| 23100416 |
Hu BH et al.:
Metalloproteinases and their associated genes contribute to the functional integrity and noise-induced damage in the cochlear sensory epithelium
J Neurosci
2012
32
|
| 19590937 |
Kundu S et al.:
Matrix imbalance by inducing expression of metalloproteinase and oxidative stress in cochlea of hyperhomocysteinemic mice
Mol Cell Biochem
2009
332: 215-224
|
| 17851959 |
Moon SK et al.:
Activities of matrix metalloproteinases and tissue inhibitor of metalloproteinase-2 in idiopathic hemotympanum and otitis media with effusion
Acta Otolaryngol
2008
128: 144-150
|
| 31539539 |
Tambalo M et al.:
Enhancer activation by FGF signalling during otic induction
Dev Biol
2020
457: 69-82
|
| 20955936 |
Dror AA et al.:
Hearing impairment: a panoply of genes and functions
Neuron
2010
68: 293-308
|
| 24826990 |
von Jonquieres G et al.:
Loss of central auditory processing in a mouse model of Canavan disease
PLoS One
2014
9
|
| 24789876 |
Yamaguchi Y et al.:
Melanocytes and their diseases
|
| 32343945 |
Cunningham CL et al.:
TMIE Defines Pore and Gating Properties of the Mechanotransduction Channel of Mammalian Cochlear Hair Cells
Neuron
2020
107: 126-143.e8
|
| 23871232 |
Pan B et al.:
TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear
Neuron
2013
79: 504-515
|
| 23217710 |
Xiong W et al.:
TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells
Cell
2012
151: 1283-1295
|
| 25467981 |
Zhao B et al.:
TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells
Neuron
2014
84: 954-967
|
| 16734381 |
Goto T et al.:
Sp1 family of transcription factors regulates the human alpha2 (XI) collagen gene (COL11A2) in Saos-2 osteoblastic cells
J Bone Miner Res
2006
21: 661-673
|
| 22558334 |
Johnson KR et al.:
Mutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia
PLoS One
2012
7
|
| 32048449 |
Wu D et al.:
Clinical and genetic study of 12 Chinese Han families with nonsyndromic deafness
Mol Genet Genomic Med
2020
8: e1177
|
| 15841483 |
author information missing
article information missing
|
| 11266470 |
Hume AN et al.:
Rab27a regulates the peripheral distribution of melanosomes in melanocytes
J Cell Biol
2001
152: 795-808
|
| 11266474 |
Bahadoran P et al.:
Rab27a: A key to melanosome transport in human melanocytes
J Cell Biol
2001
152: 843-850
|
| 23656395 |
author information missing
article information missing
|
| 23019651 |
author information missing
article information missing
|
| 19416478 |
author information missing
article information missing
|
| 27862579 |
author information missing
article information missing
|
| 23337955 |
author information missing
article information missing
|
| 34900860 |
author information missing
article information missing
|
| 35104841 |
author information missing
article information missing
|
| 29265453 |
author information missing
article information missing
|
| 26852512 |
author information missing
article information missing
|
| 35913199 |
author information missing
article information missing
|
| 37138571 |
author information missing
article information missing
|
| 39071140 |
author information missing
article information missing
|
| 15338397 |
author information missing
article information missing
|
| 25339702 |
author information missing
article information missing
|
| 26792067 |
author information missing
article information missing
|
| 25339907 |
author information missing
article information missing
|
| 18309337 |
author information missing
article information missing
|
| 15576511 |
Lo Bianco C et al.:
Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinsons disease
Proc. Natl. Acad. Sci. U.S.A.
2004
101
|
| 10888878 |
Shimura H et al.:
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase.
Nat. Genet.
2000
25: 302-305
|
| 12628165 |
Staropoli JF et al.:
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity.
Neuron
2003
37: 735-749
|
| 18248624 |
Moore DJ et al.:
Parkin mediates the degradation-independent ubiquitination of Hsp70.
J. Neurochem.
2008
105: 1806-1819
|
| 16096643 |
Sato S et al.:
14-3-3eta is a novel regulator of parkin ubiquitin ligase
EMBO J.
2006
25: 211-221
|
| 11439185 |
Imai Y et al.:
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
Cell
2001
105: 891-902
|
| 12925569 |
Huynh DP et al.:
The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI
Hum. Mol. Genet.
2003
12: 2587-2597
|
| 16332688 |
Um JW et al.:
Parkin ubiquitinates and promotes the degradation of RanBP2
J. Biol. Chem.
2006
281: 3595-3603
|
| 12783850 |
Corti O et al.:
The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration
Hum. Mol. Genet.
2003
12: 1427-1437
|
| 20969476 |
Choi DH et al.:
DJ-1 cleavage by matrix metalloproteinase 3 mediates oxidative stress-induced dopaminergic cell death
Antioxid. Redox Signal.
2011
14: 2137-2150
|
| 18822273 |
Ramsey CP et al.:
The E163K DJ-1 mutant shows specific antioxidant deficiency
Brain Res.
2008
1239: 1-11
|
| 16352719 |
Smith WW et al.:
Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration
Proc. Natl. Acad. Sci. U.S.A.
2005
102
|
| 10464279 |
Jensen PH et al.:
alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356.
J. Biol. Chem.
1999
274
|
| 19628698 |
Junn E et al.:
Repression of alpha-synuclein expression and toxicity by microRNA-7.
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 19628698 |
Junn E et al.:
Repression of alpha-synuclein expression and toxicity by microRNA-7
Proc. Natl. Acad. Sci. U.S.A.
2009
106
|
| 18322646 |
Parihar MS et al.:
Mitochondrial association of alpha-synuclein causes oxidative stress.
Cell. Mol. Life Sci.
2008
65: 1272-1284
|
| 19242547 |
Liu W et al.:
PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinsons disease.
PLoS ONE
2009
4: E4597
|
| 16805805 |
Muqit MM et al.:
Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress.
J. Neurochem.
2006
98: 156-169
|
| 19152501 |
Weihofen A et al.:
Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking.
Biochemistry
2009
48: 2045-2052
|
| 19358826 |
Shiba K et al.:
Parkin stabilizes PINK1 through direct interaction
Biochem. Biophys. Res. Commun.
2009
383: 331-335
|
| 19229105 |
Xiong H et al.:
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation.
J. Clin. Invest.
2009
119: 650-660
|
| 18957282 |
Kim Y et al.:
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation.
Biochem. Biophys. Res. Commun.
2008
377: 975-980
|
| 16449237 |
Kuroda Y et al.:
Parkin enhances mitochondrial biogenesis in proliferating cells.
Hum. Mol. Genet.
2006
15: 883-895
|
| 19279012 |
Dagda RK et al.:
Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission.
J. Biol. Chem.
2009
284
|
| 19076428 |
Plun-Favreau H et al.:
What have PINK1 and HtrA2 genes told us about the role of mitochondria in Parkinsons disease?
Ann. N. Y. Acad. Sci.
2008
1147: 30-36
|
| 17906618 |
Plun-Favreau H et al.:
The mitochondrial protease HtrA2 is regulated by Parkinsons disease-associated kinase PINK1
Nat. Cell Biol.
2007
9: 1243-1252
|
| 17906618 |
Plun-Favreau H et al.:
The mitochondrial protease HtrA2 is regulated by Parkinsons disease-associated kinase PINK1.
Nat. Cell Biol.
2007
9: 1243-1252
|
| 16269541 |
West AB et al.:
Parkinsons disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
Proc. Natl. Acad. Sci. U.S.A.
2005
46
|
| 16321986 |
Gloeckner CJ et al.:
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity.
Hum. Mol. Genet.
2006
15: 223-232
|
| 17409193 |
Iaccarino C et al.:
Apoptotic mechanisms in mutant LRRK2-mediated cell death.
Hum. Mol. Genet.
2007
16: 1319-1326
|
| 19119233 |
Yang Q et al.:
Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy.
Science
2009
323: 124-127
|
| 19119233 |
Yang Q et al.:
Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy
Science
2009
323: 124-127
|
| 18566453 |
Vogiatzi T et al.:
Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells.
J. Biol. Chem.
2008
283
|
| 18566453 |
Vogiatzi T et al.:
Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
J. Biol. Chem.
2008
283
|
| 19057915 |
Guerrero R et al.:
Hyperphosphorylated tau aggregates in the cortex and hippocampus of transgenic mice with mutant human FTDP-17 Tau and lacking the PARK2 gene.
Acta Neuropathol.
2009
117: 159-168
|
| 19890007 |
Parisiadou L et al.:
Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis
J. Neurosci.
2009
29
|
| 19196961 |
Ko HS et al.:
CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity.
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 2897-2902
|
| 19196961 |
Ko HS et al.:
CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 2897-2902
|
| 19302196 |
Gloeckner CJ et al.:
The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro.
J. Neurochem.
2009
109: 959-968
|
| 17447891 |
Jaleel M et al.:
LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinsons disease mutants affect kinase activity.
Biochem. J.
2007
405: 307-317
|
| 17447891 |
Jaleel M et al.:
LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinsons disease mutants affect kinase activity
Biochem. J.
2007
405: 307-317
|
| 17114044 |
MacLeod D et al.:
The familial Parkinsonism gene LRRK2 regulates neurite process morphology.
Neuron
2006
52: 587-593
|
| 19536328 |
Ding X et al.:
Regulation of LRRK2 stability by the E3 ubiquitin ligase CHIP.
PLoS ONE
2009
4: E5949
|
| 18367605 |
Wang L et al.:
The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2
J. Neurosci.
2008
13: 3384-3391
|
| 18367605 |
Wang L et al.:
The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.
J. Neurosci.
2008
28: 3384-3391
|
| 19176810 |
Ho CC et al.:
The Parkinson disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegeneration.
J. Neurosci.
2009
29: 1011-1016
|
| 19176810 |
Ho CC et al.:
The Parkinson disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegeneration
J. Neurosci.
2009
29: 1011-1016
|
| 11264300 |
Hartmann A et al.:
Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinsons disease, but pathway inhibition results in neuronal necrosis.
J. Neurosci.
2001
21: 2247-2255
|
| 16971520 |
McCoy MK et al.:
Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinsons disease.
J. Neurosci.
2006
26: 9365-9375
|
| 19027715 |
Covy JP et al.:
Identification of compounds that inhibit the kinase activity of leucine-rich repeat kinase 2.
Biochem. Biophys. Res. Commun.
2009
378: 473-477
|
| 19733152 |
Greggio E et al.:
The Parkinsons disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites.
Biochem. Biophys. Res. Commun.
2009
389: 449-454
|
| 19576176 |
Qing H et al.:
Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implications.
Biochem. Biophys. Res. Commun.
2009
387: 149-152
|
| 19545277 |
Gillardon F et al.:
Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability--a point of convergence in parkinsonian neurodegeneration? }, authors { names std { { name ml Gillardon F, affil str Boehringer Ingelheim Pharma GmbH & Co KG, Birkendorfer Str. 65, 88397 Biberach an der Riss, Germany. Frank.Gillardon@bc.boehringer-ingelheim.com } } }, from journal { title { iso-jta J. Neurochem
J. Neurochem.
2009
5: 1514-1522
|
| 19545277 |
Gillardon F et al.:
Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability--a point of convergence in parkinsonian neurodegeneration
J. Neurochem.
2009
110: 1514-1522
|
| 18214993 |
Gandhi PN et al.:
The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules
J. Neurosci. Res.
2008
8: 1711-1720
|
| 17213182 |
Kim JM et al.:
Identification of genes related to Parkinsons disease using expressed sequence tags.
DNA Res.
2006
13: 275-286
|
| 15966006 |
Noureddine MA et al.:
Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra.
Mov. Disord.
2005
20: 1299-1309
|
| 6823561 |
Langston JW et al.:
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis.
Science
1983
219: 979-980
|
| 16098973 |
Cappelletti G et al.:
The parkinsonism producing neurotoxin MPP+ affects microtubule dynamics by acting as a destabilising factor.
FEBS Lett.
2005
579: 4781-4786
|
| 2861548 |
Nicklas WJ et al.:
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
Life Sci.
1985
36: 2503-2508
|
| 11406316 |
Conn KJ et al.:
Decreased expression of the NADH:ubiquinone oxidoreductase (complex I) subunit 4 in 1-methyl-4-phenylpyridinium -treated human neuroblastoma SH-SY5Y cells
Neurosci. Lett.
2001
3: 145-148
|
| 12716939 |
Ren Y et al.:
Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation
J. Neurosci.
2003
8: 3316-3324
|
| 11698390 |
Alim MA et al.:
Tubulin seeds alpha-synuclein fibril formation
J. Biol. Chem.
2002
277: 2112-2117
|
| 16750377 |
Greggio E et al.:
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin.
Neurobiol. Dis.
2006
23: 329-341
|
| 19251702 |
Samann J et al.:
Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth.
J. Biol. Chem.
2009
284
|
| 19001729 |
Zheng XY et al.:
Screening of LRRK2 interactants by yeast 2-hybrid analysis.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
2008
33: 883-891
|
| 19740074 |
Nichols RJ et al.:
Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinsons disease.
Biochem. J.
2009
424: 47-60
|
| 18701920 |
Imai Y et al.:
Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila
EMBO J.
2008
27: 2432-2443
|
| 18701920 |
Imai Y et al.:
Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila.
EMBO J.
2008
27: 2432-2443
|
| 19684592 |
Tain LS et al.:
Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss
Nat. Neurosci.
2009
12: 1129-1135
|
| 18675914 |
Liou AK et al.:
Wild-type LRRK2 but not its mutant attenuates stress-induced cell death via ERK pathway.
Neurobiol. Dis.
2008
32: 116-124
|
| 17385669 |
White LR et al.:
MAPK-pathway activity, Lrrk2 G2019S, and Parkinsons disease
J. Neurosci. Res.
2007
85: 1288-1294
|
| 19640926 |
Alegre-Abarrategui J et al.:
LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
Hum. Mol. Genet.
2009
21: 4022-4034
|
| 18182054 |
Plowey ED et al.:
Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells.
J. Neurochem.
2008
105: 1048-1056
|
| 17200184 |
Zhu JH et al.:
Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death
Am. J. Pathol.
2007
170: 75-86
|
| 15333840 |
Cuervo AM et al.:
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy.
Science
2004
305: 1292-1295
|
| 12868068 |
Gomez-Santos C et al.:
Dopamine induces autophagic cell death and alpha-synuclein increase in human neuroblastoma SH-SY5Y cells.
J. Neurosci. Res.
2003
73: 341-350
|
| 20057503 |
Michiorri S et al.:
The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy
Cell Death Differ.
2010
17: 962-974
|
| 17579517 |
Pridgeon JW et al.:
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1.
PLoS Biol.
2007
5: E172
|
| 19029340 |
Narendra D et al.:
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
J Cell Biol
2008
183: 795-803
|
| 17989306 |
Exner N et al.:
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.
J. Neurosci.
2007
27
|
| 19966284 |
Vives-Bauza C et al.:
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 378-383
|
| 19492085 |
Sandebring A et al.:
Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.
PLoS ONE
2009
4: E5701
|
| 19270741 |
Gegg ME et al.:
Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells
PLoS ONE
2009
4: E4756
|
| 20098416 |
Geisler S et al.:
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
Nat Cell Biol
2010
12: 119-131
|
| 17846173 |
Olzmann JA et al.:
Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6.
J. Cell Biol.
2007
178: 1025-1038
|
| 20035503 |
Elstner M et al.:
Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinsons disease gene
Ann. Neurol.
2009
66: 792-798
|
| 17260967 |
Ito G et al.:
GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinsons disease
Biochemistry
2007
46: 1380-1388
|
| 17200152 |
West AB et al.:
Parkinsons disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity.
Hum. Mol. Genet.
2007
16: 223-232
|
| 19769964 |
Heo HY et al.:
LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity
Exp. Cell Res.
2010
316: 649-656
|
| 20064389 |
Lin X et al.:
Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinsons-disease-related mutant alpha-synuclein
Neuron
2009
64: 807-827
|
| 19625296 |
Sancho RM et al.:
Mutations in the LRRK2 Roc-COR tandem domain link Parkinsons disease to Wnt signalling pathways.
Hum. Mol. Genet.
2009
18: 3955-3968
|
| 19591802 |
Rawal N et al.:
Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling
Biochem. Biophys. Res. Commun.
2009
388: 473-478
|
| 19591802 |
Rawal N et al.:
Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling.
Biochem. Biophys. Res. Commun.
2009
388: 473-478
|
| 19692353 |
Venderova K et al.:
Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinsons disease.
Hum. Mol. Genet.
2009
18: 4390-4404
|
| 19741132 |
Ng CH et al.:
Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila.
J. Neurosci.
2009
29
|
| 20090955 |
Kumar A et al.:
The Parkinsons disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation
PLoS ONE
2010
5: E8730
|
| 20090955 |
Kumar A et al.:
The Parkinsons disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation.
PLoS ONE
2010
5: E8730
|
| 20144646 |
Dachsel JC et al.:
Heterodimerization of Lrrk1-Lrrk2: Implications for LRRK2-associated Parkinson disease
Mech. Ageing Dev.
2010
131: 210-214
|
| 18665912 |
Rodriguez-Blanco J et al.:
Intracellular signaling pathways involved in post-mitotic dopaminergic PC12 cell death induced by 6-hydroxydopamine.
J. Neurochem.
2008
107: 127-140
|
| 19712061 |
Klein CL et al.:
Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment.
J. Neurochem.
2009
111: 703-715
|
| 17368428 |
Marchionini DM et al.:
Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinsons disease.
Brain Res.
2007
1147: 77-88
|
| 18436529 |
Tetzlaff JE et al.:
CHIP targets toxic alpha-Synuclein oligomers for degradation.
J. Biol. Chem.
2008
283
|
| 17512523 |
Lim MK et al.:
Parkin interacts with LIM Kinase 1 and reduces its cofilin-phosphorylation activity via ubiquitination
Exp. Cell Res.
2007
313: 2858-2874
|
| 15358157 |
McLean PJ et al.:
Geldanamycin induces Hsp70 and prevents alpha-synuclein aggregation and toxicity in vitro.
Biochem. Biophys. Res. Commun.
2004
321: 665-669
|
| 20133810 |
Jang SW et al.:
A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 2687-2692
|
| 20133810 |
Jang SW et al.:
A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone.
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 2687-2692
|
| 18230735 |
Deng J et al.:
Structure of the ROC domain from the Parkinsons disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase.
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 1499-1504
|
| 17341485 |
Hatano T et al.:
Leucine-rich repeat kinase 2 associates with lipid rafts.
Hum. Mol. Genet.
2007
16: 678-690
|
| 17442267 |
Lewis PA et al.:
The R1441C mutation of LRRK2 disrupts GTP hydrolysis.
Biochem. Biophys. Res. Commun.
2007
357: 668-671
|
| 17346966 |
Sakaguchi-Nakashima A et al.:
LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins
Curr. Biol.
2007
17: 592-598
|
| 18445495 |
Shin N et al.:
LRRK2 regulates synaptic vesicle endocytosis.
Exp. Cell Res.
2008
314: 2055-2065
|
| 19748892 |
Fishman-Jacob T et al.:
A sporadic Parkinson disease model via silencing of the ubiquitin-proteasome/E3 ligase component SKP1A.
J. Biol. Chem.
2009
284
|
| 17400507 |
Dachsel JC et al.:
Identification of potential protein interactors of Lrrk2.
Parkinsonism Relat. Disord.
2007
13: 382-385
|
| 11821392 |
Ahn BH et al.:
alpha-Synuclein interacts with phospholipase D isozymes and inhibits pervanadate-induced phospholipase D activation in human embryonic kidney-293 cells.
J. Biol. Chem.
2002
277
|
| 11137760 |
McNaught KS et al.:
Proteasomal function is impaired in substantia nigra in Parkinsons disease.
Neurosci. Lett.
2001
297: 191-194
|
| 11431533 |
Shimura H et al.:
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinsons disease.
Science
2001
293: 263-269
|
| 11739566 |
Stefanis L et al.:
Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.
J. Neurosci.
2001
21: 9549-9560
|
| 15934949 |
Rideout HJ et al.:
Dopaminergic neurons in rat ventral midbrain cultures undergo selective apoptosis and form inclusions, but do not up-regulate iHSP70, following proteasomal inhibition.
J. Neurochem.
2005
93: 1304-1313
|
| 19182805 |
Gitler AD et al.:
Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity.
Nat. Genet.
2009
41: 308-315
|
| 16964263 |
Ramirez A et al.:
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase.
Nat. Genet.
2006
38: 1184-1191
|
| 7998774 |
Mann VM et al.:
Complex I, iron, and ferritin in Parkinsons disease substantia nigra.
Ann. Neurol.
1994
36: 876-881
|
| 18258746 |
Liu Z et al.:
A Drosophila model for LRRK2-linked parkinsonism
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 2693-2698
|
| 18258746 |
Liu Z et al.:
A Drosophila model for LRRK2-linked parkinsonism.
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 2693-2698
|
| 20133695 |
Aleyasin H et al.:
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway
Proc. Natl. Acad. Sci. U.S.A.
2010
7: 3186-3191
|
| 20133695 |
Aleyasin H et al.:
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway.
Proc. Natl. Acad. Sci. U.S.A.
2010
107: 3186-3191
|
| 19800394 |
Timmons S et al.:
Akt signal transduction dysfunction in Parkinsons disease.
Neurosci. Lett.
2009
467: 30-35
|
| 17116866 |
Ries V et al.:
Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinsons disease.
Proc. Natl. Acad. Sci. U.S.A.
2006
103
|
| 16862145 |
Fallon L et al.:
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling.
Nat. Cell Biol.
2006
8: 834-842
|
| 16862145 |
Fallon L et al.:
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling
Nat. Cell Biol.
2006
8: 834-842
|
| 19801972 |
da Costa CA et al.:
Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinsons disease.
Nat. Cell Biol.
2009
11: 1370-1375
|
| 18845538 |
Liu M et al.:
Parkin regulates Eg5 expression by Hsp70 ubiquitination-dependent inactivation of c-Jun NH2-terminal kinase.
J. Biol. Chem.
2008
283
|
| 17314283 |
Henn IH et al.:
Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling.
J. Neurosci.
2007
27: 1868-1878
|
| 18398426 |
Jung AE et al.:
HSP70 and constitutively active HSF1 mediate protection against CDCrel-1-mediated toxicity.
Mol. Ther.
2008
16: 1048-1055
|
| 20016108 |
Kadkhodaei B et al.:
Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons.
J. Neurosci.
2009
29
|
| 20230807 |
Singh K et al.:
Nicotine- and caffeine-mediated changes in gene expression patterns of MPTP-lesioned mouse striatum: Implications in neuroprotection mechanism.
Chem. Biol. Interact.
2010
185: 81-93
|
| 20404107 |
Matsuda N et al.:
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.
J. Cell Biol.
2010
189: 211-221
|
| 9070310 |
Nagakubo D et al.:
DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras.
Biochem. Biophys. Res. Commun.
1997
231: 509-513
|
| 17015834 |
Clements CM et al.:
DJ-1, a cancer- and Parkinsons disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2.
Proc. Natl. Acad. Sci. U.S.A.
2006
103
|
| 15312971 |
van Muiswinkel FL et al.:
Expression of NAD(P)H:quinone oxidoreductase in the normal and Parkinsonian substantia nigra.
Neurobiol. Aging
2004
25: 1253-1262
|
| 17015834 |
Clements CM et al.:
DJ-1, a cancer- and Parkinsons disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
Proc Natl Acad Sci U S A
2006
103
|
| 20377612 |
Gan L et al.:
Keap1-Nrf2 activation in the presence and absence of DJ-1
Eur J Neurosci
2010
31: 967-977
|
| 20377612 |
Gan L et al.:
Keap1-Nrf2 activation in the presence and absence of DJ-1
Eur. J. Neurosci.
2010
31: 967-977
|
| 15181200 |
Canet-Aviles RM et al.:
The Parkinsons disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization.
Proc. Natl. Acad. Sci. U.S.A.
2004
101: 9103-9108
|
| 17766438 |
Andres-Mateos E et al.:
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase.
Proc. Natl. Acad. Sci. U.S.A.
2007
104
|
| 20202476 |
Niso-Santano M et al.:
Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis
Free Radic. Biol. Med.
2010
48: 1370-1381
|
| 20196834 |
von Otter M et al.:
Association of Nrf2-encoding NFE2L2 haplotypes with Parkinsons disease.
BMC Med. Genet.
2010
11: 36
|
| 17982879 |
Wruck CJ et al.:
Luteolin protects rat PC12 and C6 cells against MPP+ induced toxicity via an ERK dependent Keap1-Nrf2-ARE pathway
|
| 16227205 |
Zhou W et al.:
DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity
J. Biol. Chem.
2005
280
|
| 16227205 |
Zhou W et al.:
DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity
J. Biol. Chem.
2005
280
|
| 11477070 |
Takahashi K et al.:
DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor.
J. Biol. Chem.
2001
276
|
| 18689799 |
Zhong N et al.:
Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1alpha: regulation by SUMOylation and oxidation
Hum. Mol. Genet.
2008
17: 3357-3367
|
| 18689799 |
Zhong N et al.:
Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1alpha: regulation by SUMOylation and oxidation.
Hum. Mol. Genet.
2008
17: 3357-3367
|
| 16731528 |
Zhong N et al.:
DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor.
J. Biol. Chem.
2006
281
|
| 12612053 |
Niki T et al.:
DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex.
Mol. Cancer Res.
2003
1: 247-261
|
| 15790595 |
Xu J et al.:
The Parkinsons disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis.
Hum. Mol. Genet.
2005
14: 1231-1241
|
| 19703902 |
Ishikawa S et al.:
Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1.
J. Biol. Chem.
2009
284
|
| 19694908 |
Kitada T et al.:
Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice.
J. Neurochem.
2009
111: 696-702
|
| 20127688 |
Opsahl JA et al.:
Increased interaction between DJ-1 and the Mi-2/ nucleosome remodelling and deacetylase complex during cellular stress.
Proteomics
2010
10: 1494-1504
|
| 18042550 |
Fan J et al.:
DJ-1 decreases Bax expression through repressing p53 transcriptional activity.
J. Biol. Chem.
2008
283: 4022-4030
|
| 18042550 |
Fan J et al.:
DJ-1 decreases Bax expression through repressing p53 transcriptional activity
J. Biol. Chem.
2008
283: 4022-4030
|
| 20213747 |
Mo JS et al.:
DJ-1 modulates the p38 mitogen-activated protein kinase pathway through physical interaction with apoptosis signal-regulating kinase 1.
J. Cell. Biochem.
2010
110: 229-237
|
| 19822128 |
Hayashi T et al.:
DJ-1 binds to mitochondrial complex I and maintains its activity
Biochem. Biophys. Res. Commun.
2009
3: 667-672
|
| 19822128 |
Hayashi T et al.:
DJ-1 binds to mitochondrial complex I and maintains its activity.
Biochem. Biophys. Res. Commun.
2009
390: 667-672
|
| 2154550 |
Schapira AH et al.:
Mitochondrial complex I deficiency in Parkinsons disease.
J. Neurochem.
1990
54: 823-827
|
| 18309325 |
Mo JS et al.:
DJ-1 modulates UV-induced oxidative stress signaling through the suppression of MEKK1 and cell death.
Cell Death Differ.
2008
15: 1030-1041
|
| 15983381 |
Junn E et al.:
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death.
Proc. Natl. Acad. Sci. U.S.A.
2005
102: 9691-9696
|
| 19146923 |
Blackinton J et al.:
Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease
Neurosci. Lett.
2009
452: 8-11
|
| 18974921 |
Lev N et al.:
DJ-1 protects against dopamine toxicity.
J Neural Transm
2009
116: 151-160
|
| 20074637 |
Carballo-Carbajal I et al.:
Leucine-rich repeat kinase 2 induces alpha-synuclein expression via the extracellular signal-regulated kinase pathway.
Cell. Signal.
2010
22: 821-827
|
| 19023331 |
Zucchelli S et al.:
Aggresome-forming TTRAP mediates pro-apoptotic properties of Parkinsons disease-associated DJ-1 missense mutations.
Cell Death Differ.
2009
16: 428-438
|
| 20014998 |
Saeed U et al.:
DJ-1 loss by glutaredoxin but not glutathione depletion triggers Daxx translocation and cell death
Antioxid. Redox Signal.
2010
13: 127-144
|
| 19293155 |
Waak J et al.:
Oxidizable residues mediating protein stability and cytoprotective interaction of DJ-1 with apoptosis signal-regulating kinase 1.
J. Biol. Chem.
2009
284
|
| 19276172 |
Waak J et al.:
Regulation of astrocyte inflammatory responses by the Parkinsons disease-associated gene DJ-1
FASEB J.
2009
23: 2478-2489
|
| 19261853 |
Liu Z et al.:
Membrane-associated farnesylated UCH-L1 promotes alpha-synuclein neurotoxicity and is a therapeutic target for Parkinsons disease.
Proc. Natl. Acad. Sci. U.S.A.
2009
106: 4635-4640
|
| 20423606 |
Chung YC et al.:
The role of neuroinflammation on the pathogenesis of Parkinsons disease.
BMB Rep
2010
43: 225-232
|
| 20025058 |
Kim SR et al.:
Prothrombin kringle-2 induces death of mesencephalic dopaminergic neurons in vivo and in vitro via microglial activation.
J. Neurosci. Res.
2010
88: 1537-1548
|
| 20025058 |
Kim SR et al.:
Prothrombin kringle-2 induces death of mesencephalic dopaminergic neurons in vivo and in vitro via microglial activation
J. Neurosci. Res.
2010
88: 1537-1548
|
| 20041858 |
Hu LF et al.:
Neuroprotective effects of hydrogen sulfide on Parkinsons disease rat models.
Aging Cell
2010
9: 135-146
|
| 20098715 |
Sanchez-Guajardo V et al.:
Microglia acquire distinct activation profiles depending on the degree of alpha-synuclein neuropathology in a rAAV based model of Parkinsons disease.
PLoS ONE
2010
5: E8784
|
| 18582534 |
Brodacki B et al.:
Serum interleukin (IL-2, IL-10, IL-6, IL-4), TNFalpha, and INFgamma concentrations are elevated in patients with atypical and idiopathic parkinsonism.
Neurosci. Lett.
2008
441: 158-162
|
| 7700568 |
Mogi M et al.:
Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients.
Neurosci. Lett.
1994
180: 147-150
|
| 19345186 |
Saijo K et al.:
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death
Cell
2009
137: 47-59
|
| 19295143 |
Chung CY et al.:
Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy
J Neurosci
2009
29: 3365-3373
|
| 18686098 |
Panaro MA et al.:
Expression of TLR4 and CD14 in the central nervous system (CNS) in a MPTP mouse model of Parkinsons-like disease.
Immunopharmacol Immunotoxicol
2008
30: 729-740
|
| 12496759 |
Le WD et al.:
Mutations in NR4A2 associated with familial Parkinson disease.
Nat. Genet.
2003
33: 85-89
|
| 12496759 |
Le WD et al.:
Mutations in NR4A2 associated with familial Parkinson disease
Nat. Genet.
2003
33: 85-89
|
| 20511551 |
Lee EJ et al.:
Alpha-synuclein activates microglia by inducing the expressions of matrix metalloproteinases and the subsequent activation of protease-activated receptor-1
J. Immunol.
2010
185: 615-623
|
| 20511551 |
Lee EJ et al.:
Alpha-synuclein activates microglia by inducing the expressions of matrix metalloproteinases and the subsequent activation of protease-activated receptor-1
J. Immunol.
2010
185: 615-623
|
| 12460604 |
Lorenzl S et al.:
Expression of MMP-2, MMP-9, and MMP-1 and their endogenous counterregulators TIMP-1 and TIMP-2 in postmortem brain tissue of Parkinsons disease.
Exp. Neurol.
2002
178: 13-20
|
| 15075439 |
Lorenzl S et al.:
Matrix metalloproteinase-9 is elevated in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice.
Neuromolecular Med.
2004
5: 119-132
|
| 17166628 |
Klegeris A et al.:
Alpha-synuclein activates stress signaling protein kinases in THP-1 cells and microglia
Neurobiol. Aging
2008
29: 739-752
|
| 15864310 |
Matsuzawa A et al.:
ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.
Nat. Immunol.
2005
6: 587-592
|
| 20106983 |
Doxakis E et al.:
Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153.
J. Biol. Chem.
2010
285
|
| 20409326 |
Gu XL et al.:
Astrocytic expression of Parkinsons disease-related A53T alpha-synuclein causes neurodegeneration in mice
Mol Brain
2010
3: 12
|
| 17012252 |
Klegeris A et al.:
Alpha-synuclein and its disease-causing mutants induce ICAM-1 and IL-6 in human astrocytes and astrocytoma cells
FASEB J.
2006
20: 2000-2008
|
| 17012252 |
Klegeris A et al.:
Alpha-synuclein and its disease-causing mutants induce ICAM-1 and IL-6 in human astrocytes and astrocytoma cells
FASEB J.
2006
20: 2000-2008
|
| 17537546 |
Su X et al.:
Synuclein activates microglia in a model of Parkinsons disease
Neurobiol. Aging
2008
29: 1690-1701
|
| 15163680 |
Thomas DM et al.:
Methamphetamine neurotoxicity in dopamine nerve endings of the striatum is associated with microglial activation
J. Pharmacol. Exp. Ther.
2004
311: 1-7
|
| 16467537 |
Min KJ et al.:
Astrocytes induce hemeoxygenase-1 expression in microglia: a feasible mechanism for preventing excessive brain inflammation
J. Neurosci.
2006
26: 1880-1887
|
| 16467537 |
Min KJ et al.:
Astrocytes induce hemeoxygenase-1 expression in microglia: a feasible mechanism for preventing excessive brain inflammation
J Neurosci
2006
26: 1880-1887
|
| 20074453 |
Wilms H et al.:
Suppression of MAP kinases inhibits microglial activation and attenuates neuronal cell death induced by alpha-synuclein protofibrils
Int J Immunopathol Pharmacol
2009
22: 897-909
|
| 19104149 |
Brochard V et al.:
Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease
J. Clin. Invest.
2009
119: 182-192
|
| 18449945 |
Park JY et al.:
Microglial phagocytosis is enhanced by monomeric alpha-synuclein, not aggregated alpha-synuclein: implications for Parkinsons disease
Glia
2008
56: 1215-1223
|
| 11517237 |
Bal-Price A et al.:
Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity
J. Neurosci.
2001
21: 6480-6491
|
| 19616617 |
Hoang T et al.:
Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease
Free Radic. Biol. Med.
2009
47: 1049-1056
|
| 17116747 |
Kim YS et al.:
A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation
FASEB J.
2007
1: 179-187
|
| 18981141 |
Hu X et al.:
Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinsons disease
J. Immunol.
2008
181: 7194-7204
|
| 17600340 |
Zhang W et al.:
Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein
Glia
2007
55: 1178-1188
|
| 11880505 |
Wu DC et al.:
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
J. Neurosci.
2002
22: 1763-1771
|
| 18808450 |
Chen X et al.:
Caffeine protects against MPTP-induced blood-brain barrier dysfunction in mouse striatum
J. Neurochem.
2008
4: 1147-1157
|
| 18808450 |
Chen X et al.:
Caffeine protects against MPTP-induced blood-brain barrier dysfunction in mouse striatum
J. Neurochem.
2008
107: 1147-1157
|
| 17234424 |
Zhao C et al.:
TNF-alpha knockout and minocycline treatment attenuates blood-brain barrier leakage in MPTP-treated mice
Neurobiol. Dis.
2007
1: 36-46
|
| 17437543 |
Rite I et al.:
Blood-brain barrier disruption induces in vivo degeneration of nigral dopaminergic neurons
J. Neurochem.
2007
6: 1567-1582
|
| 15668963 |
Kortekaas R et al.:
Blood-brain barrier dysfunction in parkinsonian midbrain in vivo
Ann. Neurol.
2005
57: 176-179
|
| 12649371 |
Liu Y et al.:
Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation
J. Pharmacol. Exp. Ther.
2003
305: 212-218
|
| 20423606 |
Chung YC et al.:
The role of neuroinflammation on the pathogenesis of Parkinsons disease
BMB Rep
2010
43: 225-232
|
| 19864567 |
Ghosh A et al.:
Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinsons disease
J. Neurosci.
2009
29
|
| 20671708 |
Gehrke S et al.:
Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
Nature
2010
466: 637-641
|
| 19059336 |
Banerjee R et al.:
Mitochondrial dysfunction in the limelight of Parkinsons disease pathogenesis
Biochim. Biophys. Acta
2009
1792: 651-663
|
| 16365298 |
Perier C et al.:
Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage
Proc. Natl. Acad. Sci. U.S.A.
2005
52
|
| 18411255 |
Kyratzi E et al.:
The S18Y polymorphic variant of UCH-L1 confers an antioxidant function to neuronal cells
Hum. Mol. Genet.
2008
17: 2160-2171
|
| 18550537 |
Kabuta T et al.:
Aberrant interaction between Parkinson disease-associated mutant UCH-L1 and the lysosomal receptor for chaperone-mediated autophagy
J. Biol. Chem.
2008
283
|
| 12408865 |
Liu Y et al.:
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinsons disease susceptibility
Cell
2002
111: 209-218
|
| 20798247 |
Sriram K et al.:
Mitochondrial dysfunction and loss of Parkinsons disease-linked proteins contribute to neurotoxicity of manganese-containing welding fumes
FASEB J.
2010
24: 4989-5002
|
| 19141079 |
Yasuda T et al.:
Effects of UCH-L1 on alpha-synuclein over-expression mouse model of Parkinsons disease
J. Neurochem.
2009
108: 932-944
|
| 20720502 |
Vitte J et al.:
Leucine-rich repeat kinase 2 is associated with the endoplasmic reticulum in dopaminergic neurons and accumulates in the core of Lewy bodies in Parkinson disease
J. Neuropathol. Exp. Neurol.
2010
69: 959-972
|
| 20729864 |
Lee BD et al.:
Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinsons disease
Nat. Med.
2010
16: 998-1000
|
| 20642453 |
Nichols RJ et al.:
14-3-3 binding to LRRK2 is disrupted by multiple Parkinsons disease-associated mutations and regulates cytoplasmic localization
Biochem. J.
2010
430: 393-404
|
| 10407019 |
Ostrerova N et al.:
alpha-Synuclein shares physical and functional homology with 14-3-3 proteins
J. Neurosci.
1999
19: 5782-5791
|
| 16957925 |
Shirakashi Y et al.:
alpha-Synuclein is colocalized with 14-3-3 and synphilin-1 in A53T transgenic mice
Acta Neuropathol.
2006
112: 681-689
|
| 19289463 |
Wang J et al.:
14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: localization of dopamine regulatory proteins to mitochondria
J. Biol. Chem.
2009
284
|
| 19289463 |
Wang J et al.:
14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: localization of dopamine regulatory proteins to mitochondria
J. Biol. Chem.
2009
284
|
| 11943812 |
Perez RG et al.:
A role for alpha-synuclein in the regulation of dopamine biosynthesis
J. Neurosci.
2002
22: 3090-3099
|
| 20659021 |
Dzamko N et al.:
Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser(910)/Ser(935), disruption of 14-3-3 binding and altered cytoplasmic localization
Biochem. J.
2010
430: 405-413
|
| 20152114 |
Nemani VM et al.:
Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis
Neuron
2010
65: 66-79
|
| 17108165 |
Larsen KE et al.:
Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis
J. Neurosci.
2006
26
|
| 19553450 |
Taylor TN et al.:
Nonmotor symptoms of Parkinsons disease revealed in an animal model with reduced monoamine storage capacity
J. Neurosci.
2009
29: 8103-8113
|
| 20080893 |
Okamura N et al.:
In vivo measurement of vesicular monoamine transporter type 2 density in Parkinson disease with (18)F-AV-133
J. Nucl. Med.
2010
51: 223-228
|
| 20508036 |
Rakovic A et al.:
Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients
Hum. Mol. Genet.
2010
19: 3124-3137
|
| 20126261 |
Narendra DP et al.:
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
PLoS Biol.
2010
8
|
| 18560593 |
Wood-Kaczmar A et al.:
PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons
PLoS ONE
2008
3: E2455
|
| 20045449 |
Klinkenberg M et al.:
Enhanced vulnerability of PARK6 patient skin fibroblasts to apoptosis induced by proteasomal stress
Neuroscience
2010
166: 422-434
|
| 19285945 |
Gandhi S et al.:
PINK1-associated Parkinsons disease is caused by neuronal vulnerability to calcium-induced cell death
Mol. Cell
2009
33: 627-638
|
| 18443288 |
Yang Y et al.:
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
Proc. Natl. Acad. Sci. U.S.A.
2008
105: 7070-7075
|
| 20855506 |
Winslow AR et al.:
alpha-Synuclein impairs macroautophagy: implications for Parkinsons disease.
J. Cell Biol.
2010
190: 1023-1037
|
| 21152247 |
Yacoubian TA et al.:
Differential neuroprotective effects of 14-3-3 proteins in models of Parkinsons disease.
Cell Death Dis
2010
1: E2
|
| 19617636 |
Rothfuss O et al.:
Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair
Hum. Mol. Genet.
2009
18: 3832-3850
|
| 20800516 |
Xu X et al.:
The familial Parkinsons disease gene DJ-1 (PARK7) is expressed in red cells and plays a role in protection against oxidative damage
Blood Cells Mol. Dis.
2010
45: 227-232
|
| 20457763 |
Lee JY et al.:
Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
J. Cell Biol.
2010
189: 671-679
|
| 20724841 |
Matsuda N et al.:
Uncovering the roles of PINK1 and parkin in mitophagy
Autophagy
2010
6: 952-954
|
| 19786829 |
Cherra SJ 3rd et al.:
Mitochondrial autophagy as a compensatory response to PINK1 deficiency
Autophagy
2009
5: 1213-1214
|
| 20871098 |
Gegg ME et al.:
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
Hum. Mol. Genet.
2010
19: 4861-4870
|
| 20064504 |
Kieper N et al.:
Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1
Exp. Cell Res.
2010
316: 1213-1224
|
| 20064504 |
Kieper N et al.:
Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1
Exp. Cell Res.
2010
316: 1213-1224
|
| 20890124 |
Narendra D et al.:
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
Autophagy
2010
6: 1090-1106
|
| 20889486 |
Rose JM et al.:
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
Hum. Mol. Genet.
2011
1: 16-27
|
| 20889974 |
Chen D et al.:
Parkin mono-ubiquitinates Bcl-2 and regulates autophagy
J. Biol. Chem.
2010
285
|
| 20173338 |
Fishman-Jacob T et al.:
Silencing/overexpressing selected genes as a model of sporadic Parkinsons disease
Neurodegener Dis
2010
7: 108-111
|
| 14593166 |
Dawson TM et al.:
Molecular pathways of neurodegeneration in Parkinsons disease
Science
2003
302: 819-822
|
| 20890446 |
Navarro A et al.:
Brain mitochondrial dysfunction in aging, neurodegeneration, and Parkinsons disease
|
| 20946892 |
Kim IS et al.:
A novel synthetic compound PHID (8-Phenyl-6a, 7, 8, 9, 9a, 10-hexahydro-6H-isoindolo [5, 6-g] quinoxaline-7, 9-dione) protects SH-SY5Y cells against MPP(+)-induced cytotoxicity through inhibition of reactive oxygen species generation and JNK signaling
Eur. J. Pharmacol.
2011
650: 48-57
|
| 20885945 |
Grunewald A et al.:
Mutant Parkin impairs mitochondrial function and morphology in human fibroblasts
PLoS ONE
2010
5
|
| 20890618 |
Gomez FJ et al.:
Iron mediates neuritic tree collapse in mesencephalic neurons treated with 1-methyl-4-phenylpyridinium (MPP+)
J Neural Transm
2011
118: 421-431
|
| 20445061 |
Jowaed A et al.:
Methylation regulates alpha-synuclein expression and is decreased in Parkinsons disease patients brains
J. Neurosci.
2010
30: 6355-6359
|
| 18332041 |
Grundemann J et al.:
Elevated alpha-synuclein mRNA levels in individual UV-laser-microdissected dopaminergic substantia nigra neurons in idiopathic Parkinsons disease
Nucleic Acids Res.
2008
36: E38
|
| 20185556 |
Smith WW et al.:
Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model
Hum. Mol. Genet.
2010
19: 2087-2098
|
| 20649842 |
Johansen JL et al.:
HIF prolyl hydroxylase inhibition increases cell viability and potentiates dopamine release in dopaminergic cells
J. Neurochem.
2010
115: 209-219
|
| 19748892 |
Fishman-Jacob T et al.:
A sporadic Parkinson disease model via silencing of the ubiquitin-proteasome/E3 ligase component SKP1A
J. Biol. Chem.
2009
284
|
| 20872781 |
Xu H et al.:
Rg1 protects iron-induced neurotoxicity through antioxidant and iron regulatory proteins in 6-OHDA-treated MES23.5 cells
J. Cell. Biochem.
2010
111: 1537-1545
|
| 19022250 |
Levin J et al.:
Increased alpha-synuclein aggregation following limited cleavage by certain matrix metalloproteinases
Exp. Neurol.
2009
215: 201-208
|
| 20926834 |
Zheng B et al.:
PGC-1alpha, a potential therapeutic target for early intervention in Parkinsons disease
Sci Transl Med
2010
2: 52RA73
|
| 21040713 |
Lee M et al.:
Mg2+ ions reduce microglial and THP-1 cell neurotoxicity by inhibiting Ca2+ entry through purinergic channels
Brain Res.
2011
1369: 21-35
|
| 20940149 |
Thomas KJ et al.:
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
Hum. Mol. Genet.
2011
20: 40-50
|
| 18626009 |
van der Brug MP et al.:
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways
Proc. Natl. Acad. Sci. U.S.A.
2008
105
|
| 20842103 |
Kamp F et al. et al.:
Inhibition of mitochondrial fusion by alpha-synuclein is rescued by PINK1, Parkin and DJ-1
EMBO J
2010
29: 3571-3589
|
| 16794039 |
Cooper AA et al.:
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinsons models
Science
2006
313: 324-328
|
| 16794039 |
Cooper AA et al.:
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinsons models
Science
2006
313: 324-328
|
| 20227462 |
Mei J et al.:
Alterations of Hrd1 expression in various encephalic regional neurons in 6-OHDA model of Parkinsons disease
Neurosci. Lett.
2010
474: 63-68
|
| 20186954 |
Tan EK et al.:
PLA2G6 mutations and Parkinsons disease
Ann. Neurol.
2010
67: 148
|
| 20700524 |
Kang KS et al.:
Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: in vitro and in vivo studies
PLoS ONE
2010
5
|
| 20340137 |
Voutsinas GE et al.:
Allelic imbalance of expression and epigenetic regulation within the alpha-synuclein wild-type and p.Ala53Thr alleles in Parkinson disease
Hum. Mutat.
2010
31: 685-691
|
| 16269331 |
Chandra S et al.:
Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration
Cell
2005
123: 383-396
|
| 15590933 |
Yavich L et al.:
Role of alpha-synuclein in presynaptic dopamine recruitment
J. Neurosci.
2004
24
|
| 18980610 |
Ben Gedalya T et al.:
Alpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recycling
Traffic
2009
10: 218-234
|
| 20971673 |
Nishioka K et al.:
Genetic variation of the mitochondrial complex I subunit NDUFV2 and Parkinsons disease
Parkinsonism Relat. Disord.
2010
16: 686-687
|
| 3399080 |
McGeer PL et al.:
Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinsons and Alzheimers disease brains
Neurology
1988
38: 1285-1291
|
| 20071342 |
Lee HJ et al.:
Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies
J. Biol. Chem.
2010
285: 9262-9272
|
| 18716210 |
Lee JK et al.:
Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response
J. Neurosci.
2008
28: 8517-8528
|
| 18945890 |
Frank-Cannon TC et al.:
Parkin deficiency increases vulnerability to inflammation-related nigral degeneration
J. Neurosci.
2008
28
|
| 19879328 |
Deng S et al.:
Genetic analysis of the NEUROG2 gene in patients with Parkinsons disease.
Neurosci. Lett.
2010
468: 195-197
|
| 22507762 |
Lauterbach EC et al.:
Psychotropic drug effects on gene transcriptomics relevant to Parkinsons disease
Prog. Neuropsychopharmacol. Biol. Psychiatry
2012
38: 107-115
|
| 16972276 |
Kumru H et al.:
Increase in body weight after pramipexole treatment in Parkinsons disease
Mov. Disord.
2006
21: 1972-1974
|
| 16261618 |
Nirenberg MJ et al.:
Compulsive eating and weight gain related to dopamine agonist use
Mov. Disord.
2006
21: 524-529
|
| 21988495 |
van Dijk KD et al.:
The proteome of the locus ceruleus in Parkinsons disease: relevance to pathogenesis
Brain Pathol.
2012
22: 485-498
|
| 26008206 |
Gao J et al.:
Parkin-induced ubiquitination of Mff promotes its association with p62/SQSTM1 during mitochondrial depolarization
Acta Biochim. Biophys. Sin. (Shanghai)
2015
47: 522-529
|
| 27997702 |
Liu JP et al.:
Impulse control disorder, lysosomal malfunction and ATP13A2 insufficiency in Parkinsonism
Clin. Exp. Pharmacol. Physiol.
2017
44: 172-179
|
| 28166239 |
Ciesielska A et al.:
Depletion of AADC activity in caudate nucleus and putamen of Parkinsons disease patients; implications for ongoing AAV2-AADC gene therapy trial
PLoS ONE
2017
12
|
| 26317511 |
Su X et al.:
PGC-1alpha Promoter Methylation in Parkinsons Disease
PLoS ONE
2015
10
|
| 25597950 |
Garcia-Esparcia P et al.:
Purine metabolism gene deregulation in Parkinsons disease
Neuropathol. Appl. Neurobiol.
2015
41: 926-940
|
| 23648388 |
Liu H et al.:
Association of P2X7 receptor gene polymorphisms with sporadic Parkinsons disease in a Han Chinese population
Neurosci. Lett.
2013
546: 42-45
|
| 30597610 |
Atashrazm F et al.:
LRRK2-mediated Rab10 phosphorylation in immune cells from Parkinsons disease patients
Mov. Disord.
2019
34: 406-415
|
| 29330884 |
Longhena F et al. et al.:
Synapsin III is a key component of alpha-synuclein fibrils in Lewy bodies of PD brains
Brain Pathol.
2018
28: 875-888
|
| 25967550 |
Zaltieri M et al. et al.:
alpha-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons
J. Cell. Sci.
2015
128: 2231-2243
|
| 27611585 |
Mariani E et al.:
Meta-Analysis of Parkinsons Disease Transcriptome Data Using TRAM Software: Whole Substantia Nigra Tissue and Single Dopamine Neuron Differential Gene Expression
PLoS ONE
2016
11
|
| 18462474 |
Bossers K et al.:
Analysis of gene expression in Parkinsons disease: possible involvement of neurotrophic support and axon guidance in dopaminergic cell death
Brain Pathol.
2009
19: 91-107
|
| 19859963 |
Tamariz E et al.:
Axon responses of embryonic stem cell-derived dopaminergic neurons to semaphorins 3A and 3C
J. Neurosci. Res.
2010
88: 971-980
|
| 30995519 |
Miller S et al.:
Therapeutic approaches to enhance PINK1/Parkin mediated mitophagy for the treatment of Parkinsons disease
Neurosci. Lett.
2019
705: 7-13
|
| 22003392 |
Martins M et al. et al.:
Convergence of miRNA expression profiling, alpha-synuclein interacton and GWAS in Parkinsons disease
PLoS ONE
2011
6
|
| 30093493 |
Kumar N et al.:
VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites
J. Cell Biol.
2018
217: 3625-3639
|
| 31234232 |
Fernandez-Santiago R et al. et al.:
SNCA and mTOR Pathway Single Nucleotide Polymorphisms Interact to Modulate the Age at Onset of Parkinsons Disease
Mov. Disord.
2019
34: 1333-1344
|
| 32124967 |
Tan YX et al.:
MicroRNA449a regulates the progression of brain aging by targeting SCN2B in SAMP8 mice
Int. J. Mol. Med.
2020
45: 1091-1102
|
| 16092945 |
Son JH et al. et al.:
Neurotoxicity and behavioral deficits associated with Septin 5 accumulation in dopaminergic neurons
J. Neurochem.
2005
94: 1040-1053
|
| 31814881 |
Rahimmi A et al.:
miR-185 and SEPT5 Genes May Contribute to Parkinsons Disease Pathophysiology
Oxid Med Cell Longev
2019
2019
|
| 16037097 |
von Bohlen und Halbach O et al.:
Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra
FASEB J.
2005
19: 1740-1742
|
| 19162339 |
Lin L et al.:
Axon guidance and synaptic maintenance: preclinical markers for neurodegenerative disease and therapeutics
Trends Neurosci.
2009
32: 142-149
|
| 21818119 |
Lim L et al.:
Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinsons disease
Cell Death Differ.
2012
19: 416-427
|
| 25556233 |
Shi M et al. et al.:
Cerebrospinal fluid peptides as potential Parkinson disease biomarkers: a staged pipeline for discovery and validation
Mol. Cell Proteomics
2015
14: 544-555
|
| 28335819 |
Oerton E et al.:
Concordance analysis of microarray studies identifies representative gene expression changes in Parkinsons disease: a comparison of 33 human and animal studies
BMC Neurol
2017
17: 58
|
| 28892059 |
Chang D et al. et al.:
A meta-analysis of genome-wide association studies identifies 17 new Parkinsons disease risk loci
Nat. Genet.
2017
49: 1511-1516
|
| 30256453 |
Gaare JJ et al.:
Rare genetic variation in mitochondrial pathways influences the risk for Parkinsons disease
Mov. Disord.
2018
33: 1591-1600
|
| 28899360 |
Chatterjee P et al.:
Biological networks in Parkinsons disease: an insight into the epigenetic mechanisms associated with this disease
BMC Genomics
2017
18: 721
|
| 32139796 |
Keo A et al. et al.:
Transcriptomic signatures of brain regional vulnerability to Parkinsons disease
Commun Biol
2020
3: 101
|
| 31920912 |
Germer EL et al.:
The Role of Rare Coding Variants in Parkinsons Disease GWAS Loci
Front Neurol
2019
10: 1284
|
| 25501810 |
et al.:
LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism
J. Cell. Sci.
2015
128: 541###52
|
| 31750563 |
Chang MY et al. et al.:
LIN28A loss of function is associated with Parkinsons disease pathogenesis
EMBO J.
2019
38
|
| 31310388 |
Eskandarian Boroujeni M et al.:
Complementation of dopaminergic signaling by Pitx3-GDNF synergy induces dopamine secretion by multipotent Ntera2 cells
J. Cell. Biochem.
2020
121: 200-212
|
| 28991698 |
Backstrom D et al.:
PITX3 genotype and risk of dementia in Parkinsons disease: A population-based study
J. Neurol. Sci.
2017
381: 278-284
|
| 21524731 |
Liu J et al.:
PITX3 gene polymorphism is associated with Parkinsons disease in Chinese population
Brain Res.
2011
1392: 116-120
|
| 32741046 |
Dyavar SR et al.:
Transcriptomic approach predicts a major role for transforming growth factor beta type 1 pathway in L-Dopa-induced dyskinesia in parkinsonian rats
|
| 11900856 |
Gearhart DA et al.:
Phenylethanolamine N-methyltransferase has beta-carboline 2N-methyltransferase activity: hypothetical relevance to Parkinsons disease
Neurochem. Int.
2002
40: 611-620
|
| 26499758 |
Chung SJ et al.:
Association of type 2 diabetes GWAS loci and the risk of Parkinsons and Alzheimers diseases
Parkinsonism Relat. Disord.
2015
21: 1435-1440
|
| 25583483 |
Kurup PK et al.:
STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinsons disease
Proc. Natl. Acad. Sci. U.S.A.
2015
112: 1202-1207
|
| 29315801 |
Gao Y et al.:
The emerging role of Rab GTPases in the pathogenesis of Parkinsons disease
Mov. Disord.
2018
33: 196-207
|
| 29681884 |
Jewett M et al.:
Glutathione S-Transferase Alpha 4 Prevents Dopamine Neurodegeneration in a Rat Alpha-Synuclein Model of Parkinsons Disease
Front Neurol
2018
9: 222
|
| 26545632 |
Choong CJ et al.:
A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinsons disease
Neurobiol. Aging
2016
37: 103-116
|
| 29936662 |
Fan Y et al.:
Progression Rate Associated Peripheral Blood Biomarkers of Parkinsons Disease
J. Mol. Neurosci.
2018
65: 312-318
|
| 32082315 |
Sarkar S et al. et al.:
Molecular Signatures of Neuroinflammation Induced by alphaSynuclein Aggregates in Microglial Cells
Front Immunol
2020
11: 33
|
| 22859504 |
Pham AH et al.:
Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit
Hum. Mol. Genet.
2012
21: 4817-4826
|
| 30277602 |
Neal M et al.:
Prokineticin-2 promotes chemotaxis and alternative A2 reactivity of astrocytes
Glia
2018
66: 2137-2157
|
| 25296989 |
Holmqvist S et al.:
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
Acta Neuropathol
2014
128: 805-820
|
| 11192626 |
Glavan G et al.:
Dopaminergic regulation of synaptotagmin I and IV mRNAs in hemiparkinsonian rats
Neuroreport
2000
11: 4043-4047
|
| 23213621 |
Wright JW et al.:
Importance of the brain Angiotensin system in Parkinsons disease
Parkinsons Dis
2012
2012
|
| 20888078 |
Villar-Cheda B et al.:
Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration
Neurobiol Aging
2012
33: 204.e1-204.11
|
| 20580712 |
Rodriguez-Perez AI et al.:
Estrogen and angiotensin interaction in the substantia nigra. Relevance to postmenopausal Parkinsons disease
Exp Neurol
2010
224: 517-526
|
| 20964730 |
Villar-Cheda B et al.:
Nigral and striatal regulation of angiotensin receptor expression by dopamine and angiotensin in rodents: implications for progression of Parkinsons disease
Eur J Neurosci
2010
32: 1695-1706
|
| 21846363 |
Rodriguez-Perez AI et al.:
Renin angiotensin system and gender differences in dopaminergic degeneration
Mol Neurodegener
2011
6: 58
|
| 22407459 |
Garrido-Gil P et al.:
Expression of angiotensinogen and receptors for angiotensin and prorenin in the monkey and human substantia nigra: an intracellular renin-angiotensin system in the nigra
Brain Struct Funct
2013
218: 373-388
|
| 2377609 |
Milsted A et al.:
Astrocyte cultures derived from human brain tissue express angiotensinogen mRNA
Proc Natl Acad Sci U S A
1990
87: 5720-5723
|
| 27733642 |
Ou Z et al.:
Mitochondrial-dependent mechanisms are involved in angiotensin II-induced apoptosis in dopaminergic neurons
|
| 24231739 |
author information missing
article information missing
|
| 36423813 |
author information missing
article information missing
|
| 38358016 |
author information missing
article information missing
|
| 39075566 |
author information missing
article information missing
|
| 39364348 |
author information missing
article information missing
|
| 37838622 |
author information missing
article information missing
|
| 24983211 |
author information missing
article information missing
|
| 39060467 |
author information missing
article information missing
|
| 25689258 |
author information missing
article information missing
|
| 38178977 |
author information missing
article information missing
|
| 35715418 |
author information missing
article information missing
|
| 23409742 |
Ferri L et al.:
New clinical and molecular insights on Barth syndrome
Orphanet J Rare Dis
2013
8: 27
|
| 24044064 |
Sharef SW et al.:
Successful Treatment of Cardiomyopathy due to Very Long-Chain Acyl-CoA Dehydrogenase Deficiency: First Case Report from Oman with Literature Review
Oman Med J
2013
28: 354-356
|
| 21931170 |
Fassone E et al.:
Mutations in the mitochondrial complex I assembly factor NDUFAF1 cause fatal infantile hypertrophic cardiomyopathy
J. Med. Genet.
2011
48: 691-697
|
| 17564966 |
He M et al.:
A new genetic disorder in mitochondrial fatty acid beta-oxidation: ACAD9 deficiency
Am. J. Hum. Genet.
2007
81: 87-103
|
| 26669660 |
Collet M et al.:
High incidence and variable clinical outcome of cardiac hypertrophy due to ACAD9 mutations in childhood
Eur. J. Hum. Genet.
2016
24: 1112-1116
|
| 17187068 |
Klein C et al.:
HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease)
Nat. Genet.
2007
39: 86-92
|
| 19524642 |
Fadeel B et al.:
HAX-1: a multifunctional protein with emerging roles in human disease
Biochim. Biophys. Acta
2009
1790: 1139-1148
|
| 19679660 |
Jitkaew S et al.:
N(alpha)-tosyl-L-phenylalanine chloromethyl ketone induces caspase-dependent apoptosis in transformed human B cell lines with transcriptional down-regulation of anti-apoptotic HS1-associated protein X-1
J. Biol. Chem.
2009
284
|
| 18288109 |
Chao JR et al.:
Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons
Nature
2008
452: 98-102
|
CIDeRplus