Search is restricted to the following diseases:
Search Results for "Valproic acid" - 43 interactions found in 13 entries.
|
|
|
Interactor1 (Subject) |
|
Interaction type |
Interactor2 (Object) |
additional information |
|
|
|
|
548
|
| 5926 |
Valproic acid
|
|
decreases_quantity of
|
Asparagine
|
in pilocarpine model
|
| 5927 |
Valproic acid
|
|
decreases_quantity of
|
Glutamate
|
in pilocarpine model
|
|
18439803
|
Status epilepticus
|
|
717
|
| 4012 |
Valproic acid
|
|
affects_processing of
|
APP
|
|
| 4017 |
Valproic acid
|
|
decreases_quantity of
|
Amyloid beta peptide (40)
|
|
| 10903 |
Valproic acid
|
|
decreases_quantity of
|
Amyloid beta peptide (42)
|
|
|
15170327
|
Alzheimer disease
|
|
718
|
| 4014 |
Valproic acid
|
|
affects_processing of
|
APP
|
|
| 4019 |
Valproic acid
|
|
decreases_quantity of
|
Amyloid beta peptide (40)
|
|
| 5840 |
Valproic acid
|
|
decreases_quantity of
|
Amyloid beta peptide (42)
|
|
|
15170327
|
Alzheimer disease
|
|
3,388
|
| 31809 |
Valproic acid
|
|
increases_activity of
|
secondary carnitine deficiency
|
|
| 31813 |
Valproic acid
|
|
decreases_activity of
|
Status epilepticus
|
|
| 31814 |
Valproic acid
|
|
decreases_quantity of
|
2-Oxoglutarate
|
|
|
22134503
|
Diabetes mellitus, type II
Carnitine deficiency, systemic primary
Insulin resistance
Status epilepticus
Cardiovascular disease
|
|
6,206
|
| 57887 |
Valproic acid
|
|
decreases_activity of
|
HDAC3
|
|
| 58400 |
Valproic acid
|
|
decreases_phosphorylation of
|
AKT1
|
if AKT phosphorylation is induced by temsirolimus.
|
| 58403 |
Valproic acid
|
|
decreases_expression of
|
HDAC1
|
|
| 58406 |
Valproic acid
|
|
decreases_activity of
|
AKT1
|
via HDAC3
|
| 58407 |
Valproic acid
|
|
increases_activity of
|
autophagy
|
through down-regulation of MTOR pathway.
|
| 58408 |
Valproic acid
|
|
decreases_activity of
|
TOR signaling
|
|
| 58411 |
Valproic acid
|
|
decreases_activity of
|
HDAC1
|
|
| 58412 |
Valproic acid
|
|
increases_expression of
|
CDKN1A
|
|
| 58413 |
Valproic acid
|
|
increases_expression of
|
CDKN1B
|
|
| 58415 |
Valproic acid
|
|
increases_activity of
|
Temsirolimus
|
|
| 58416 |
Temsirolimus
|
|
increases_activity of
|
Valproic acid
|
|
|
23866964
|
Burkitt lymphoma
Cancer
|
|
6,260
|
| 58574 |
Valproic acid
|
|
increases_activity of
|
increased cellular sensitivity to X-ray irradiation
|
in SF539 and U251 glioma cells
|
| 58619 |
Valproic acid
|
|
decreases_activity of
|
HDAC
|
in SF539 and U251 glioma cells
|
| 58620 |
Valproic acid
|
|
increases_phosphorylation of
|
H2AX
|
in SF539 and U251 glioma cells
|
| 58621 |
Valproic acid
|
|
decreases_activity of
|
DNA repair
|
in SF539 and U251 glioma cells
|
|
15578701
|
Glioblastoma
|
|
6,261
|
| 58576 |
Valproic acid
|
|
increases_activity of
|
increased cancer survival time
|
|
|
21362133
|
Glioblastoma
|
|
6,270
|
| 58622 |
Valproic acid
|
|
increases_activity of
|
increased cellular sensitivity to X-ray irradiation
|
|
| 58623 |
Valproic acid
|
|
increases_activity of
|
decreased tumor growth/size
|
|
| 58624 |
Valproic acid
|
|
decreases_activity of
|
HDAC
|
|
|
15578701
|
Glioblastoma
|
|
6,295
|
| 60989 |
Valproic acid
|
|
decreases_activity of
|
HDAC1
|
|
| 60990 |
Valproic acid
|
|
decreases_activity of
|
HDAC2
|
|
| 60991 |
Valproic acid
|
|
decreases_activity of
|
CoREST complex
|
|
| 60992 |
Valproic acid
|
|
decreases_activity of
|
NuRD complex
|
|
|
|
Cancer
|
|
6,356
|
| 59558 |
Valproic acid
|
|
increases_activity of
|
AKT/TOR signaling
|
in DU-145 prostata cancer cells
|
| 59565 |
Valproic acid
|
|
increases_activity of
|
histone H3 acetylation
|
in DU-145 prostata cancer cells
|
| 59566 |
Valproic acid
|
|
increases_activity of
|
histone H4 acetylation
|
in DU-145 prostata cancer cells
|
|
24779401
|
Prostate cancer
|
|
8,154
|
| 81919 |
Valproic acid
|
|
increases_expression of
|
SOX5
|
|
| 81920 |
Valproic acid
|
|
increases_activity of
|
insulin secretion involved in cellular response to glucose stimulus
|
|
|
28585545
|
Diabetes mellitus, type II
Insulin resistance
|
|
9,689
|
| 102250 |
Valproic acid
|
|
increases_activity of
|
MAOA
|
|
| 102281 |
Valproic acid
|
|
increases_expression of
|
MAOA
|
|
|
29163009
|
Metabolic
Major depressive disorder
Anxiety disorders
|
|
15,346
|
| 145095 |
Valproic acid
|
|
decreases_activity of
|
inositol biosynthetic process
|
|
| 145098 |
Valproic acid
|
|
decreases_quantity of
|
Inositol
|
via inhibiting inositol synthesis
|
|
|
Alzheimer disease
|
CIDeRplus