|
419
|
| 1831 |
GPAM
|
|
affects_quantity of
|
Reactive oxygen species
|
in liver mitochondria
|
|
17258706
|
Diabetes mellitus, type II
Insulin resistance
|
|
496
|
| 2466 |
Isoproterenol
|
|
increases_quantity of
|
Reactive oxygen species
|
in adipose tissue
|
| 2467 |
Compound C
|
|
increases_quantity of
|
Reactive oxygen species
|
in adipose tissue
|
| 2468 |
Isoproterenol
|
|
affects_quantity of
|
Reactive oxygen species
|
|
| 12771 |
Compound C
|
|
affects_quantity of
|
Reactive oxygen species
|
|
| 12772 |
Compound C
|
|
increases_quantity of
|
Reactive oxygen species
|
|
|
18390901
|
Diabetes mellitus, type II
Insulin resistance
|
|
685
|
| 3723 |
LRRK2
|
|
increases_quantity of
|
Reactive oxygen species
|
if overexpressed
|
| 3725 |
LRRK2-p.G2019S
|
|
increases_quantity of
|
Reactive oxygen species
|
amount of ROS was increased even with a higher rate than wild type
|
|
19769964
|
Parkinson disease
|
|
737
|
| 4127 |
6-OHDA
|
|
increases_quantity of
|
Reactive oxygen species
|
|
|
18665912
|
Parkinson disease
|
|
772
|
| 4356 |
aging
|
|
increases_quantity of
|
Reactive oxygen species
|
in skeletal muscle mitochondria
|
| 4357 |
Reactive oxygen species
|
|
increases_activity of
|
muscle atrophy
|
|
|
17584954
|
Amyotrophic lateral sclerosis
|
|
774
|
| 4363 |
SOD1
|
|
decreases_quantity of
|
Reactive oxygen species
|
in skeletal muscle mitochondria
|
|
17584954
|
Amyotrophic lateral sclerosis
|
|
777
|
| 4367 |
SOD1-p.G93A
|
|
increases_quantity of
|
Reactive oxygen species
|
in skeletal muscle mitochondria
|
|
17584954
|
Amyotrophic lateral sclerosis
|
|
908
|
| 5418 |
Reactive oxygen species
|
|
increases_activity of
|
Alzheimer disease
|
|
| 5419 |
Amyloid beta peptide
|
|
increases_quantity of
|
Reactive oxygen species
|
in neuron; through an NMDA receptor-dependent process
|
| 5421 |
Reactive oxygen species
|
|
increases_activity of
|
abnormal mitochondrial physiology
|
in astrocytes
|
| 5423 |
Reactive oxygen species
|
|
increases_activity of
|
inflammatory response
|
in astrocytes; if ROS production is Abeta-induced
|
| 5430 |
Reactive oxygen species
|
|
increases_activity of
|
cytokine production
|
in astrocytes; if ROS production is Abeta-induced
|
| 5432 |
Reactive oxygen species
|
|
increases_activity of
|
nitric oxide production involved in inflammatory response
|
in astrocytes; if ROS production is Abeta-induced
|
| 5435 |
Reactive oxygen species
|
|
increases_activity of
|
icosanoid metabolic process
|
in astrocytes; if ROS production is Abeta-induced
|
| 5441 |
Reactive oxygen species
|
|
increases_activity of
|
neuron death
|
in astrocytes; if ROS production is Abeta-induced
|
| 10999 |
Reactive oxygen species
|
|
increases_activity of
|
Parkinson disease
|
|
|
19191039
|
Alzheimer disease
|
|
989
|
| 6145 |
Paraquat
|
|
increases_quantity of
|
Reactive oxygen species
|
|
|
20202476
|
Parkinson disease
|
|
999
|
| 6204 |
amyloid beta deposits
|
|
increases_quantity of
|
Reactive oxygen species
|
|
|
17086105
|
Alzheimer disease
|
|
1,005
|
| 6282 |
PARK7
|
|
decreases_quantity of
|
Reactive oxygen species
|
after oxidative stress
|
| 6283 |
PARK7-p.L166P
|
NOT |
decreases_quantity of
|
Reactive oxygen species
|
after oxidative stress
|
|
16227205
|
Parkinson disease
|
|
1,012
|
| 6313 |
SOD2
|
|
decreases_quantity of
|
Reactive oxygen species
|
|
| 6314 |
GPX1
|
|
decreases_quantity of
|
Reactive oxygen species
|
|
| 6315 |
GCLC
|
|
decreases_quantity of
|
Reactive oxygen species
|
|
| 6316 |
CAT
|
|
decreases_quantity of
|
Reactive oxygen species
|
|
|
18689799
|
Parkinson disease
|
|
1,068
|
| 6840 |
CDK5
|
|
affects_quantity of
|
Reactive oxygen species
|
depending of glutamate stimulation
|
| 6841 |
Glutamate
|
|
increases_quantity of
|
Reactive oxygen species
|
|
| 6843 |
Amyloid beta peptide (25-35)
|
|
increases_quantity of
|
Reactive oxygen species
|
2.5-fold increase in ROS levels, Cdk5-dependent
|
|
18691386
|
Alzheimer disease
|
|
1,070
|
| 6742 |
Dopamine
|
|
increases_quantity of
|
Reactive oxygen species
|
|
| 6743 |
PARK7
|
|
decreases_quantity of
|
Reactive oxygen species
|
|
| 6744 |
Reactive oxygen species
|
|
increases_quantity of
|
PARK7
|
|
|
18974921
|
Parkinson disease
|
|
1,074
|
| 6790 |
PROC-mut
|
|
decreases_quantity of
|
Reactive oxygen species
|
|
| 6794 |
PROC-p.S360A
|
NOT |
decreases_quantity of
|
Reactive oxygen species
|
|
|
19841542
|
Amyotrophic lateral sclerosis
|
|
1,082
|
| 6856 |
GLRX
|
|
affects_quantity of
|
Reactive oxygen species
|
|
|
20014998
|
Parkinson disease
|
|
1,107
|
| 7574 |
Curcumin
|
|
decreases_activity of
|
Reactive oxygen species
|
|
|
20462385
|
Alzheimer disease
Dementia
|
|
1,137
|
| 7395 |
SNCA
|
|
increases_quantity of
|
Reactive oxygen species
|
in microglia
|
| 7406 |
MMP3
|
|
affects_quantity of
|
Reactive oxygen species
|
after stimulation with alpha-synuclein
|
| 7410 |
MMP8
|
|
affects_quantity of
|
Reactive oxygen species
|
after stimulation with alpha-synuclein
|
| 7414 |
MMP9
|
|
affects_quantity of
|
Reactive oxygen species
|
after stimulation with alpha-synuclein
|
| 7420 |
1rmz
|
|
decreases_activity of
|
Reactive oxygen species
|
in microglia; after stimulation with alpha-synuclein
|
| 7422 |
M9I
|
|
decreases_activity of
|
Reactive oxygen species
|
in microglia; after stimulation with alpha-synuclein
|
|
20511551
|
Parkinson disease
|
|
1,184
|
| 7859 |
Amyloid beta peptide (fibrillar)
|
|
increases_quantity of
|
Reactive oxygen species
|
|
| 7860 |
NADPH oxidase complex
|
|
increases_quantity of
|
Reactive oxygen species
|
in microglia; via amyloid beta peptide
|
| 8347 |
NADPH oxidase complex
|
|
affects_quantity of
|
Reactive oxygen species
|
if ROS production is Abeta-induced
|
|
17094809
|
Alzheimer disease
Chronic granulomatous disease
|
|
1,199
|
| 8018 |
NADPH oxidase complex
|
|
increases_quantity of
|
Reactive oxygen species
|
in activated microglia cells
|
|
15791003
|
Parkinson disease
|
|
1,215
|
| 8162 |
microglial cell activation
|
|
increases_quantity of
|
Reactive oxygen species
|
in brain
|
|
17537546
|
Parkinson disease
|
|
1,218
|
| 8197 |
SNCA
|
|
increases_quantity of
|
Reactive oxygen species
|
via microglial cell activation
|
|
17537546
|
Parkinson disease
|
|
1,229
|
| 8256 |
HMOX1
|
|
decreases_quantity of
|
Reactive oxygen species
|
|
|
16467537
|
Parkinson disease
|
|
1,230
|
| 8260 |
astrocyte
|
|
decreases_quantity of
|
Reactive oxygen species
|
in microglia
|
|
16467537
|
Parkinson disease
|
|
1,276
|
| 8703 |
NADPH oxidase complex
|
|
increases_quantity of
|
Reactive oxygen species
|
in spinal cord
|
|
16877542
|
Amyotrophic lateral sclerosis
|
|
1,287
|
| 8752 |
NADPH oxidase complex
|
|
increases_quantity of
|
Reactive oxygen species
|
|
|
20423606
|
Parkinson disease
|
|
1,309
|
| 8998 |
Ibuprofen
|
|
decreases_quantity of
|
Reactive oxygen species
|
in primary microglia; if ROS-production is stimulated by fibrillar amyloid beta peptides
|
|
20696495
|
Alzheimer disease
|
|
1,356
|
| 9280 |
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
|
|
increases_quantity of
|
Reactive oxygen species
|
in mitochondria
|
|
16365298
|
Parkinson disease
|
|
1,360
|
| 9309 |
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
|
|
increases_quantity of
|
Reactive oxygen species
|
|
| 9310 |
UCHL1
|
NOT |
decreases_quantity of
|
Reactive oxygen species
|
after treatment with MPTP
|
| 9311 |
UCHL1-p.S18Y
|
|
decreases_quantity of
|
Reactive oxygen species
|
after treatment with MPTP
|
|
18411255
|
Parkinson disease
|
|
1,377
|
| 9527 |
Reactive oxygen species
|
|
increases_quantity of
|
Amyloid beta peptide (phenoxy radical Tyr-10)
|
|
| 9773 |
response to hypoxia
|
|
increases_quantity of
|
Reactive oxygen species
|
via the mitochondrial transport chain, specifically by the function of complex III
|
|
20552043
|
Alzheimer disease
|
CIDeRplus