966
|
6099 |
Phosphatidylinositol 3-kinase (PIK3CA, PIK3R1)
|
|
increases_quantity of
|
XIAP
|
|
6103 |
AKT1
|
|
increases_quantity of
|
XIAP
|
|
|
15339911
|
Amyotrophic lateral sclerosis
|
975
|
5994 |
response to endoplasmic reticulum stress
|
|
increases_expression of
|
XIAP
|
|
5996 |
XIAP
|
|
decreases_activity of
|
cell death
|
|
|
15339911
|
Amyotrophic lateral sclerosis
|
2,989
|
27277 |
response to nitric oxide
|
|
decreases_activity of
|
XIAP
|
|
27318 |
XIAP
|
|
decreases_activity of
|
cysteine-type endopeptidase activity involved in apoptotic process
|
|
|
21902456
|
Alzheimer disease
|
2,999
|
27297 |
Protein kinase C
|
|
increases_activity of
|
XIAP
|
|
27312 |
Protein kinase C
|
|
increases_phosphorylation of
|
XIAP
|
at Ser87
|
27317 |
12-O-Tetradecanoylphorbol 13-acetate
|
|
increases_phosphorylation of
|
XIAP
|
at Ser87
|
|
21707856
|
Alzheimer disease
|
6,871
|
67127 |
Tos-Phe-CH2Cl
|
|
increases_processing of
|
XIAP
|
|
|
19679660
|
Neutropenia, severe congenital, 3
|
6,908
|
67577 |
XIAP
|
|
affects_activity of
|
Inflammatory bowel disease 1
|
|
67579 |
XIAP
|
|
affects_activity of
|
Lymphoproliferative syndrome, X-linked 2
|
|
67581 |
XIAP
|
|
affects_activity of
|
NOD signaling
|
|
|
|
Inflammatory bowel disease 1
Inflammatory bowel disease
|
7,042
|
68907 |
TRIM32
|
|
interacts (colocalizes) with
|
XIAP
|
|
68925 |
TRIM32
|
|
decreases_quantity of
|
XIAP
|
via ubiquitination and proteasome-dependent degradation
|
68936 |
TRIM32
|
|
increases_ubiquitination/sumoylation of
|
XIAP
|
|
|
21628460
|
Inflammation
|
7,047
|
69128 |
XIAP
|
|
affects_activity of
|
Inflammatory bowel disease
|
|
|
|
Inflammatory bowel disease
|
7,048
|
69129 |
XIAP
|
|
interacts (colocalizes) with
|
RIPK2
|
in HEK293T cells and THP-1 monocytes
|
|
|
Inflammation
|
7,049
|
69189 |
XIAP
|
|
interacts (colocalizes) with
|
RIPK2
|
|
69191 |
XIAP
|
|
increases_ubiquitination/sumoylation of
|
RIPK2
|
in THP-1 cells
|
69196 |
XIAP
|
|
increases_activity of
|
LUBAC complex
|
in HCT-116 cells
|
69293 |
XIAP
|
|
affects_activity of
|
X-linked lymphoproliferative syndrome-2
|
|
69294 |
XIAP
|
|
affects_activity of
|
Inflammatory bowel disease
|
|
|
|
Inflammatory bowel disease
Inflammation
|
7,055
|
69433 |
SIVA1
|
|
interacts (colocalizes) with
|
XIAP
|
in HeLa cells and in Jurkat T cells
|
69532 |
XIAP
|
|
increases_ubiquitination/sumoylation of
|
SIVA1
|
in Jurkat T cells
|
69533 |
XIAP
|
|
decreases_activity of
|
SIVA1
|
in Jurkat T cells ; via K48-linked ubiquitylation
|
69534 |
XIAP
|
|
decreases_activity of
|
apoptotic process
|
in Jurkat T cells ; induced by SIVA1
|
69550 |
XIAP
|
|
decreases_activity of
|
CASP3
|
|
|
|
Metabolic
|
7,057
|
69424 |
XIAP
|
|
interacts (colocalizes) with
|
TAB1
|
|
69425 |
XIAP
|
|
interacts (colocalizes) with
|
BMPR1A
|
|
|
|
Metabolic
|
7,077
|
69584 |
HAX1
|
|
decreases_ubiquitination/sumoylation of
|
XIAP
|
shown in HEK 293T cells
|
69587 |
XIAP
|
|
is_part_of
|
HAX-1-XIAP complex
|
shown in HEK 293T cells and Bosc 23 cells
|
|
|
Metabolic
|
8,974
|
93764 |
NF-kappaB complex
|
|
affects_expression of
|
XIAP
|
mediating anti-apoptotic effects
|
93766 |
Proline
|
|
increases_expression of
|
XIAP
|
received proline
orally before GalN administration, with a decline after the peak at 24 h
|
93768 |
XIAP
|
|
increases_activity of
|
negative regulation of apoptotic process
|
|
|
22585093
|
Metabolic
Inflammation
|
10,212
|
106212 |
HTRA4
|
|
interacts (colocalizes) with
|
XIAP
|
|
|
31470122
|
Cancer
Preeclampsia
|
10,213
|
106219 |
HTRA4
|
|
interacts (colocalizes) with
|
XIAP
|
|
106221 |
HTRA2
|
|
interacts (colocalizes) with
|
XIAP
|
|
|
31036715
|
Cancer
Preeclampsia
|
13,474
|
127025 |
NF-kappaB complex
|
|
increases_expression of
|
XIAP
|
|
|
25474138
|
Hepatocellular carcinoma
Cancer
|
16,197
|
156604 |
BMP2
|
|
interacts (colocalizes) with
|
XIAP
|
|
|
|
Metabolic
|
16,198
|
156605 |
XIAP
|
|
interacts (colocalizes) with
|
PRDX2
|
|
|
|
Metabolic
|