|
1,269
|
| 8617 |
Thrombin
|
|
increases_activity of
|
neuron death
|
|
| 8620 |
Thrombin
|
|
decreases_activity of
|
establishment of blood-brain barrier
|
|
|
17437543
|
Parkinson disease
|
|
2,137
|
| 17607 |
Thrombin
|
|
increases_expression of
|
CCL2
|
|
|
18483405
|
Diabetes mellitus, type II
Insulin resistance
|
|
6,115
|
| 57223 |
SERPINE2
|
|
decreases_activity of
|
Thrombin
|
in pulmonary fibroblasts
|
|
25199049
|
Pulmonary fibrosis, idiopathic
Lung disease
|
|
6,700
|
| 64723 |
Coagulation factor X
|
|
increases_quantity of
|
Thrombin
|
|
|
19598069
|
Factor X deficiency
|
|
6,712
|
| 64838 |
blood coagulation
|
|
increases_quantity of
|
Thrombin
|
|
| 64844 |
Coagulation factor X
|
|
increases_quantity of
|
Thrombin
|
|
| 64845 |
Thrombin
|
|
increases_activity of
|
blood coagulation, intrinsic pathway
|
|
| 64846 |
Thrombin
|
|
increases_activity of
|
Fibrinogen
|
|
|
|
Factor X deficiency
|
|
6,790
|
| 65942 |
F3
|
|
increases_quantity of
|
Thrombin
|
|
|
12652293
|
Metabolic
|
|
7,492
|
| 73910 |
Thrombin
|
|
increases_quantity of
|
endothelial microparticle
|
|
|
27173919
|
Diabetes mellitus, type II
Insulin resistance
Atherosclerosis
|
|
7,931
|
| 78866 |
OxLDL
|
|
increases_quantity of
|
Thrombin
|
in macrophages, in smooth muscle cells
|
|
12036878
|
Atherosclerosis
|
|
9,836
|
| 103639 |
Thrombin
|
|
increases_quantity of
|
CBL
|
in cardiomyocytes; of neonatal rats
|
|
24583314
|
Cardiomyopathy, dilated
|
|
12,080
|
| 118639 |
FVa
|
|
increases_quantity of
|
Thrombin
|
together with FXa
|
| 118640 |
F2
|
|
increases_quantity of
|
Thrombin
|
via proteolytic activity of FVa and FXa
|
| 118642 |
FXa
|
|
increases_quantity of
|
Thrombin
|
together with FVa
|
| 118644 |
Thrombin
|
|
decreases_quantity of
|
Fibrinogen
|
|
| 118645 |
Thrombin
|
|
increases_quantity of
|
Fibrin
|
|
|
32348783
|
Cardiovascular disease
COVID-19
|
|
12,083
|
| 118732 |
Thrombin
|
|
increases_activity of
|
complement activation
|
|
|
32348783
|
Cardiovascular disease
COVID-19
|
|
13,345
|
| 125922 |
Thrombin
|
|
increases_expression of
|
KDR
|
in aortic endothelial cells
|
|
11807828
|
Cardiovascular
|
|
13,346
|
| 125923 |
Thrombin
|
|
increases_expression of
|
KDR
|
in umbilical vein endothelial cells
|
| 125924 |
Thrombin
|
|
increases_activity of
|
angiogenesis
|
|
|
10446165
|
Cardiovascular
|
|
13,349
|
| 125969 |
Thrombin
|
|
affects_activity of
|
fibrinolysis
|
|
| 125972 |
Thrombin
|
|
increases_quantity of
|
PLAT
|
in glomerular cells
|
| 125973 |
Thrombin
|
|
increases_quantity of
|
PLAU
|
|
| 125974 |
Thrombin
|
|
increases_quantity of
|
SERPINE1
|
|
| 125975 |
Thrombin
|
|
affects_activity of
|
glomerulosclerosis
|
|
|
7924884
|
Nephropathy, diabetic
|
|
13,352
|
| 125986 |
Thrombin
|
|
increases_quantity of
|
PLAT
|
mesangial cells
|
| 126034 |
Thrombin
|
|
increases_quantity of
|
PLAU
|
mesangial cells
|
| 126035 |
Thrombin
|
|
increases_quantity of
|
SERPINE1
|
mesangial cells
|
|
7924884
|
Nephropathy, diabetic
|
|
13,356
|
| 126016 |
Thrombin
|
|
increases_quantity of
|
Fibrin
|
|
| 126017 |
Thrombin
|
|
decreases_quantity of
|
Fibrinogen
|
|
|
28228446
|
Hematological
|
|
13,358
|
| 126013 |
Thrombin
|
|
is_part_of
|
Thrombin-SERPINC1 complex
|
|
|
33119703
|
COVID-19
|
|
13,368
|
| 126031 |
Thrombin
|
|
affects_activity of
|
fibrinolysis
|
|
|
31309890
|
Hematological
|
|
13,377
|
| 126057 |
Thrombin
|
|
increases_expression of
|
FN1
|
in mesenchymal stem cells
|
| 126058 |
Thrombin
|
|
increases_quantity of
|
FN1
|
in mesenchymal stem cells
|
| 126059 |
Thrombin
|
|
increases_activity of
|
ERK1 and ERK2 cascade
|
in mesenchymal stem cells
|
| 126060 |
Thrombin
|
|
increases_activity of
|
NF-kappaB complex
|
in mesenchymal stem cells
|
|
|
Hematological
|
|
13,389
|
| 126341 |
MASP1
|
|
increases_quantity of
|
Thrombin
|
in normal citrated plasma
|
|
22536427
|
Hematological
Immunological
|
|
13,404
|
| 126392 |
Retinopathy, diabetic
|
|
increases_quantity of
|
Thrombin
|
in vitreous samples from patients with PDR
|
|
27261371
|
Retinopathy, diabetic
|
|
13,830
|
| 130014 |
Thrombin
|
|
increases_activity of
|
HGFAC
|
in injured tissue
|
|
10219059
|
Cancer
|
|
14,093
|
| 133240 |
COVID-19
|
|
increases_quantity of
|
Thrombin
|
|
|
32651579
|
COVID-19
|
|
14,211
|
| 134109 |
PEBP
|
|
decreases_activity of
|
Thrombin
|
|
|
17965832
|
Alzheimer disease
Metabolic
|
|
14,403
|
| 135924 |
Thrombin
|
|
increases_activity of
|
ANPEP
|
in glomerular epithelial cells
|
|
1354270
|
Renal
|
CIDeRplus