Search is restricted to the following diseases:
Search Results for "TRAF6" - 37 interactions found in 16 entries.
|
|
Interactor1 (Subject) |
|
Interaction type |
Interactor2 (Object) |
additional information |
|
|
|
564
|
69004 |
TRAF6
|
|
increases_activity of
|
Ubiquitin-conjugating enzyme E2 (UBC13-UEV1A)
|
|
|
11057907
|
Neurological
|
925
|
5618 |
PRKN
|
NOT |
increases_ubiquitination/sumoylation of
|
TRAF6
|
|
|
17314283
|
Parkinson disease
|
1,150
|
7524 |
TRAF6
|
|
affects_activity of
|
toll-like receptor signaling pathway
|
|
7526 |
TRAF6
|
|
interacts (colocalizes) with
|
MAP3K5
|
after stimulation with ligand or LPS
|
7527 |
TRAF6
|
|
increases_activity of
|
MAP3K5
|
|
|
15864310
|
Parkinson disease
|
6,972
|
68384 |
NOD2-RIPK2
|
|
increases_activity of
|
TRAF6
|
|
68385 |
TRAF6
|
|
increases_activity of
|
IKBKG
|
via ubiquitination
|
68386 |
TRAF6
|
|
increases_ubiquitination/sumoylation of
|
IKBKG
|
|
|
21252204
|
Inflammatory bowel disease
|
7,013
|
68674 |
interleukin-1-mediated signaling pathway
|
|
increases_activity of
|
TRAF6
|
|
68676 |
TRAF6
|
|
interacts (colocalizes) with
|
IRAK1
|
|
|
|
Inflammation
|
7,019
|
68781 |
TRAF4
|
|
interacts (colocalizes) with
|
TRAF6
|
thus preventing TRAF3IP2 to bind with TRAF6
|
68782 |
TRAF4
|
|
decreases_activity of
|
TRAF6
|
|
|
26376209
|
Inflammation
|
7,023
|
68769 |
TRAF3IP2
|
|
interacts (colocalizes) with
|
TRAF6
|
|
68770 |
TRAF3IP2
|
|
increases_ubiquitination/sumoylation of
|
TRAF6
|
|
68771 |
TRAF6
|
|
interacts (colocalizes) with
|
TAK1 complex
|
if TRAF6 has been ubiquitinylated
|
|
23557798
|
Inflammation
|
7,043
|
68967 |
TRAF6
|
|
increases_activity of
|
TAK1 complex
|
|
|
|
Inflammation
|
7,044
|
69076 |
TRAF6
|
|
increases_activity of
|
I-kappa-B kinase complex
|
in Jurkat and HEK293 cells
|
69077 |
MALT1
|
|
increases_activity of
|
TRAF6
|
in Jurkat cells
|
69080 |
MALT1
|
|
interacts (colocalizes) with
|
TRAF6
|
in Jurkat cells
|
69089 |
TRAF6
|
|
increases_ubiquitination/sumoylation of
|
IKBKG
|
in Jurkat cells; in the presence of the ubiquitin-conjugating enzyme (E2) complex UBC13-UEV1A
|
69106 |
TRAF6
|
|
increases_activity of
|
Ubiquitin-conjugating enzyme E2 (UBC13-UEV1A)
|
in Jurkat cells
|
69110 |
Ubiquitin-conjugating enzyme E2 (UBC13-UEV1A)
|
|
increases_ubiquitination/sumoylation of
|
TRAF6
|
in Jurkat cells
|
69111 |
TRAF6
|
|
increases_activity of
|
TAK1 complex
|
in Jurkat cells; if TRAF6 has been ubiquitinylated
|
|
|
Inflammation
|
9,435
|
100378 |
TRAF6
|
|
increases_activity of
|
protein K63-linked ubiquitination
|
|
100403 |
TRAF6
|
|
increases_activity of
|
cardiac hypertrophy
|
|
100404 |
TRAF6
|
|
increases_activity of
|
I-kappaB kinase/NF-kappaB signaling
|
|
100453 |
Angiotensin II
|
|
increases_expression of
|
TRAF6
|
in cardiomyocytes
|
100454 |
response to oxidative stress
|
|
increases_expression of
|
TRAF6
|
in cardiomyocytes
|
100455 |
TRAF6
|
|
increases_activity of
|
cardiac hypertrophy
|
|
100462 |
TRAF6
|
|
increases_activity of
|
AKT1
|
|
|
30102008
|
Cardiomyopathy, hypertrophic
|
10,678
|
109251 |
USP31
|
|
decreases_activity of
|
TRAF6
|
|
|
16214042
|
Cancer
|
11,188
|
112993 |
OTUD7A
|
|
decreases_ubiquitination/sumoylation of
|
TRAF6
|
|
|
23792447
|
Cancer
Chromosome 15q13.3 deletion syndrome
|
13,675
|
128449 |
mir-146b-5p
|
|
decreases_expression of
|
TRAF6
|
in hepatocytes
|
|
30145833
|
Cancer
|
13,892
|
131262 |
APPL1
|
|
interacts (colocalizes) with
|
TRAF6
|
|
|
28620038
|
MODY, type XIV
|
13,903
|
131359 |
TRAF6
|
|
increases_ubiquitination/sumoylation of
|
APPL1
|
|
131360 |
TRAF6
|
|
increases_activity of
|
APPL1
|
via ubiquitination at Lys63
|
|
23909487
|
Diabetes mellitus, type II
Insulin resistance
|
15,839
|
150485 |
TOMM70
|
|
interacts (colocalizes) with
|
TRAF6
|
|
|
|
Viral infection
|