|
201
|
| 797 |
TNFRSF1A
|
|
affects_expression of
|
VEGFA
|
|
| 798 |
TNFRSF1A
|
|
affects_expression of
|
EPOR
|
|
| 799 |
TNFRSF1A
|
|
affects_expression of
|
EGF
|
|
| 800 |
TNFRSF1A
|
|
affects_expression of
|
CSF1R
|
|
|
18413601
|
Amyotrophic lateral sclerosis
|
|
202
|
| 804 |
TNFRSF1A
|
|
decreases_activity of
|
neuron death
|
|
| 810 |
TNFRSF1A
|
|
decreases_activity of
|
Kainic acid
|
on apoptosis
|
|
18413601
|
Amyotrophic lateral sclerosis
|
|
1,092
|
| 7084 |
TNF
|
|
increases_activity of
|
TNFRSF1A
|
|
| 7085 |
TNFRSF1A
|
|
increases_activity of
|
IKBKB
|
|
|
18053812
|
Diabetes mellitus, type II
Obesity
Insulin resistance
|
|
1,130
|
| 7339 |
TNF
|
|
interacts (colocalizes) with
|
TNFRSF1A
|
|
|
19285115
|
Epilepsy
|
|
1,148
|
| 7489 |
TNF
|
|
interacts (colocalizes) with
|
TNFRSF1A
|
|
| 7490 |
TNFRSF1A
|
|
decreases_activity of
|
insulin receptor signaling pathway
|
|
| 7491 |
TNFRSF1A
|
|
increases_activity of
|
SMPD
|
|
| 7492 |
TNFRSF1A
|
|
increases_quantity of
|
Ceramide
|
|
|
8662983
|
Diabetes mellitus, type II
Insulin resistance
|
|
1,162
|
| 7654 |
high-fat diet
|
|
increases_expression of
|
TNFRSF1A
|
|
|
15685173
|
Diabetes mellitus, type II
Insulin resistance
|
|
1,592
|
| 11554 |
Epigallocatechin 3-gallate
|
|
decreases_expression of
|
TNFRSF1A
|
|
| 11631 |
TNFRSF1A
|
|
affects_activity of
|
inflammatory response
|
|
|
20816778
|
Diabetes mellitus, type II
Insulin resistance
|
|
2,275
|
| 19422 |
inflammatory response
|
|
increases_quantity of
|
TNFRSF1A
|
|
|
11343523
|
Major depressive disorder
|
|
3,761
|
| 36967 |
TNF, soluble
|
|
increases_activity of
|
TNFRSF1A
|
|
| 36991 |
TNF, transmembrane
|
|
increases_activity of
|
TNFRSF1A
|
|
| 36999 |
TNFRSF1A
|
|
is_expressed_in
|
neuron
|
in AD and non-demented brains
|
| 37003 |
TNFRSF1A
|
|
affects_activity of
|
neuron death
|
via a cytoplasmic death domain in TNFR1, induced by Abeta protein in the AD brain
|
| 37070 |
TNFRSF1A
|
|
increases_quantity of
|
BACE1
|
TNFR1 regulates BACE1 promoter activity via the NF-kappaB pathway.
|
| 37071 |
TNFRSF1A
|
|
increases_activity of
|
BACE1 (promoter)
|
via the NF-kappaB pathway.
|
| 82431 |
TNFRSF1A
|
|
increases_activity of
|
BACE1
|
TNFR1 regulates BACE1 promoter activity via the NF-kappaB pathway.
|
|
22970774
|
Alzheimer disease
|
|
6,285
|
| 58819 |
TNFRSF1A
|
|
interacts (colocalizes) with
|
TRPC4
|
|
| 58821 |
TNFRSF1A
|
|
interacts (colocalizes) with
|
TRPC1
|
|
| 58822 |
TNFRSF1A
|
|
interacts (colocalizes) with
|
TRPC5
|
|
| 58823 |
TRPC4AP
|
|
interacts (colocalizes) with
|
TNFRSF1A
|
|
| 58825 |
TNFRSF1A
|
|
increases_activity of
|
cell surface receptor signaling pathway
|
|
|
20458742
|
Metabolic
|
|
6,975
|
| 68411 |
TNFRSF1A
|
|
affects_activity of
|
Inflammatory bowel disease
|
|
|
24971461
|
Inflammatory bowel disease
|
|
6,983
|
| 68510 |
TNFRSF1A
|
|
increases_activity of
|
colitis
|
|
| 68512 |
TNFRSF1A
|
|
increases_activity of
|
apoptotic process
|
|
|
17361131
|
Inflammatory bowel disease
Inflammation
|
|
7,036
|
| 68858 |
CASP10
|
|
interacts (colocalizes) with
|
TNFRSF1A
|
|
|
9045686
|
Inflammation
|
|
7,053
|
| 69406 |
TNF
|
|
interacts (colocalizes) with
|
TNFRSF1A
|
|
| 69409 |
TNFRSF1A
|
|
increases_activity of
|
NF-kappaB complex
|
after binding with TNF-alpha
|
| 69410 |
TNFRSF1B
|
|
affects_activity of
|
TNFRSF1A
|
by mediating the binding of TNF to TNFRSF1A
|
| 69416 |
TNFRSF1A
|
|
affects_activity of
|
Inflammatory bowel disease
|
|
|
|
Inflammatory bowel disease
|
|
7,189
|
| 70829 |
TNFRSF1A
|
|
is localized in
|
ciliary basal body
|
|
|
20503175
|
Ciliopathy
Nephronophthisis-like nephropathy 1
|
|
9,435
|
| 100429 |
TNF
|
|
increases_activity of
|
TNFRSF1A
|
|
| 100430 |
TNFRSF1A
|
|
interacts (colocalizes) with
|
TRADD
|
|
|
30102008
|
Cardiomyopathy, hypertrophic
|
|
12,550
|
| 122064 |
MADD
|
|
increases_activity of
|
TNFRSF1A
|
|
| 122106 |
Alzheimer disease
|
|
increases_expression of
|
TNFRSF1A
|
in AD brain homogenates; compared with normal controls
|
|
26791201
|
Alzheimer disease
|
|
13,291
|
| 125647 |
End-stage renal disease
|
|
increases_quantity of
|
TNFRSF1A
|
in serum
|
|
31011203
|
Nephropathy, diabetic
|
|
13,331
|
| 125796 |
TNFRSF1A
|
|
increases_activity of
|
decreased renal glomerular filtration rate
|
in serum
|
|
30989829
|
Nephropathy, diabetic
|
|
13,332
|
| 125891 |
Nephropathy, diabetic
|
|
increases_quantity of
|
TNFRSF1A
|
|
|
|
Nephropathy, diabetic
|
|
13,338
|
| 125895 |
Nephropathy, diabetic
|
|
increases_quantity of
|
TNFRSF1A
|
in serum
|
|
|
Nephropathy, diabetic
|
|
13,418
|
| 126450 |
TNFRSF1A
|
|
increases_expression of
|
COL1A1
|
in liver cells
|
| 126455 |
TNFRSF1A
|
|
affects_activity of
|
protein kinase B signaling
|
in liver cells
|
| 126456 |
TNFRSF1A
|
|
affects_expression of
|
MMP9
|
in liver cells
|
|
21523796
|
Hematological
|
|
13,420
|
| 126460 |
TNFRSF1A
|
|
affects_quantity of
|
Fibrin
|
in hepatocytes
|
|
20218879
|
Hematological
|
|
13,460
|
| 126865 |
decreased renal glomerular filtration rate
|
|
increases_quantity of
|
TNFRSF1A
|
in blood serum
|
|
30288572
|
Diabetes mellitus, type II
Insulin resistance
Neuropathy, diabetic
|
|
13,808
|
| 129779 |
TNF
|
|
interacts (colocalizes) with
|
TNFRSF1A
|
|
| 129781 |
TNFRSF1A
|
|
affects_activity of
|
abnormal kidney physiology
|
in type I diabetes
|
|
25003613
|
Nephropathy, diabetic
|
|
15,381
|
| 145508 |
decreased renal glomerular filtration rate
|
|
decreases_quantity of
|
TNFRSF1A
|
in blood serum
|
|
|
Nephropathy, diabetic
|
CIDeRplus