|
391
|
| 1695 |
SOD1-p.G93A
|
NOT |
affects_expression of
|
TGFB1
|
in spinal cord; at 110 days of age
|
| 1696 |
Lenalidomide
|
|
increases_expression of
|
TGFB1
|
in spinal cord; in SOD1(G93A) transgenic mice at 110 days of age
|
| 1697 |
Thalidomide
|
|
increases_expression of
|
TGFB1
|
in spinal cord; in SOD1(G93A) transgenic mice at 110 days of age
|
|
16510725
|
Amyotrophic lateral sclerosis
|
|
1,107
|
| 7123 |
TGFB1
|
|
decreases_quantity of
|
amyloid beta deposits
|
in transgenic AD-prone mice; if TGFBR1 is overexpressed
|
| 79061 |
TGFB1
|
|
increases_activity of
|
amyloid-beta clearance
|
in transgenic AD-prone mice; if TGFBR1 is overexpressed
|
|
20462385
|
Alzheimer disease
Dementia
|
|
1,111
|
| 7125 |
inflammatory response
|
|
affects_activity of
|
TGFB1
|
in brain
|
| 7198 |
Alzheimer disease
|
|
increases_quantity of
|
TGFB1
|
Cerebral TGF-beta1 levels are higher in AD cases than in nondemented controls.
|
| 7219 |
TGFB1
|
|
affects_activity of
|
cerebral amyloid angiopathy
|
in AD cases; concerning cortical TGF-beta1 mRNA levels, correlating positively
|
|
11329064
|
Alzheimer disease
|
|
1,112
|
| 7126 |
TGFB1
|
|
decreases_quantity of
|
amyloid beta deposits
|
in aged transgenic hAPP mice brain; if the astroglial TGF-beta1 production is increased
|
| 7194 |
TGFB1
|
|
increases_activity of
|
microglial cell activation
|
in brain; of transgenic hAPP/TGF-beta1 mice
|
| 7220 |
TGFB1
|
|
affects_activity of
|
cerebral amyloid angiopathy
|
CAA severity correlated positively with TGF-beta1 mRNA levels;
|
|
11329064
|
Alzheimer disease
|
|
1,592
|
| 11595 |
Genistein
|
|
decreases_expression of
|
TGFB1
|
in inflamed cells
|
| 11633 |
TGFB1
|
|
affects_activity of
|
inflammatory response
|
|
|
20816778
|
Diabetes mellitus, type II
Insulin resistance
|
|
1,618
|
| 11849 |
TGFB1
|
|
decreases_expression of
|
PAX6
|
|
|
17251190
|
Neurological
|
|
2,042
|
| 118572 |
MMP2
|
|
increases_activity of
|
TGFB1
|
in the brains of APP/PS1 mice; concerning elevated mRNA levels of MMP
|
|
21376707
|
Alzheimer disease
|
|
2,070
|
| 16685 |
Diabetes mellitus, type II
|
|
increases_quantity of
|
TGFB1
|
|
| 16687 |
Ramipril
|
NOT |
increases_quantity of
|
TGFB1
|
in diabetic rats
|
| 16689 |
Insulin
|
NOT |
increases_quantity of
|
TGFB1
|
in diabetic rats
|
| 16693 |
AcSDKP
|
|
decreases_quantity of
|
TGFB1
|
in cardiac muscle; in diabetic rats
|
|
20310083
|
Diabetes mellitus, type II
Insulin resistance
|
|
2,071
|
| 16709 |
db/db mouse
|
|
increases_expression of
|
TGFB1
|
in kidney
|
| 16710 |
AcSDKP
|
NOT |
affects_expression of
|
TGFB1
|
in kidney; in db/db mice
|
|
15734863
|
Diabetes mellitus, type II
Insulin resistance
Nephropathy, diabetic
|
|
2,266
|
| 19363 |
high-fat diet
|
|
increases_expression of
|
TGFB1
|
in liver
|
| 19365 |
SPP1
|
|
affects_expression of
|
TGFB1
|
in liver
|
|
21562757
|
Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
|
|
2,786
|
| 25763 |
Resveratrol
|
|
increases_expression of
|
TGFB1
|
in colon, in liver, in muscle
|
|
21673955
|
Diabetes mellitus, type II
Insulin resistance
|
|
2,842
|
| 26199 |
Metformin
|
|
increases_expression of
|
TGFB1
|
|
|
21655990
|
Breast cancer
Diabetes mellitus, type II
Insulin resistance
|
|
2,981
|
| 27167 |
TGFB1
|
|
increases_expression of
|
KLF11
|
in pancreas, in pancreatic beta cells
|
|
15774581
|
Diabetes mellitus, type II
Insulin resistance
MODY, type VII
|
|
3,464
|
| 32285 |
TGFB1
|
|
increases_expression of
|
SMAD3
|
|
|
17164348
|
Graft-versus-host disease
|
|
3,467
|
| 32284 |
Bipolar disorder
|
|
decreases_expression of
|
TGFB1
|
|
|
11723175
|
Bipolar disorder
|
|
3,470
|
| 32290 |
response to hypoxia
|
|
increases_expression of
|
TGFB1
|
|
|
19187226
|
Hematological
|
|
3,507
|
| 32550 |
TGFB1
|
|
interacts (colocalizes) with
|
TGFBR1
|
|
|
20856203
|
Endocrine
|
|
3,508
|
| 32556 |
TGFB1
|
|
increases_activity of
|
transforming growth factor beta receptor signaling pathway
|
|
|
9525694
|
Endocrine
|
|
3,614
|
| 34181 |
Laquinimod
|
|
increases_expression of
|
TGFB1
|
in CD4+ T-and B-cells co-cultured
|
| 34184 |
Laquinimod
|
NOT |
affects_expression of
|
TGFB1
|
in T cell co-culture with pan-B cells or CD25+ B cells
|
|
22846497
|
Multiple sclerosis
|
|
3,632
|
| 34546 |
NR1H4
|
|
decreases_expression of
|
TGFB1
|
|
|
21431855
|
Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
|
|
3,646
|
| 34662 |
NR1H4
|
|
decreases_expression of
|
TGFB1
|
in liver
|
|
22187656
|
Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
|
|
3,746
|
| 36421 |
Troglitazone
|
|
decreases_expression of
|
TGFB1
|
in kidney
|
|
19002105
|
Diabetes mellitus, type II
Insulin resistance
|
|
3,749
|
| 36468 |
Pioglitazone
|
|
decreases_expression of
|
TGFB1
|
in kidney
|
|
18388116
|
Diabetes mellitus, type II
Insulin resistance
Nephropathy, diabetic
|
|
3,761
|
| 37216 |
TGFB1
|
|
decreases_activity of
|
Alzheimer disease
|
|
| 37230 |
Alzheimer disease
|
|
increases_expression of
|
TGFB1
|
in cortical brain regions; of the TgCRND8 mice, a mouse model of familial AD
|
| 37235 |
TGFB1
|
|
increases_activity of
|
abnormal vascular development
|
in brain; if TGFB1 is increased
|
|
22970774
|
Alzheimer disease
|
|
3,847
|
| 38605 |
Alzheimer disease
|
|
increases_quantity of
|
TGFB1
|
in AD patients
|
|
16688597
|
Alzheimer disease
|
|
3,929
|
| 39882 |
Naringenin
|
|
decreases_expression of
|
TGFB1
|
in kidney; in diabetic mice
|
|
22117528
|
Diabetes mellitus, type II
Insulin resistance
Nephropathy, diabetic
|
|
4,201
|
| 43114 |
hypertension
|
|
increases_expression of
|
TGFB1
|
in blood
|
|
23337395
|
Diabetes mellitus, type II
Insulin resistance
|
|
5,626
|
| 53805 |
ILK
|
|
increases_expression of
|
TGFB1
|
in the presence of RGDS
|
|
12824296
|
Metabolic
|
|
5,627
|
| 53806 |
TGFB1
|
|
increases_expression of
|
MYH7
|
|
|
23224875
|
Cardiomyopathy, hypertrophic
|
|
5,787
|
| 54624 |
TGFB1
|
|
increases_activity of
|
pulmonary fibrosis
|
|
| 54625 |
LRP5
|
|
increases_quantity of
|
TGFB1
|
in alveolar type 2 cells and leukocytes
|
|
24921217
|
Pulmonary fibrosis, idiopathic
Lung disease
|
CIDeRplus