650
|
3444 |
Status epilepticus
|
|
affects_expression of
|
SYP
|
in pilocarpine model
|
3445 |
SYP
|
|
affects_activity of
|
regulation of synapse assembly
|
in pilocarpine model
|
|
17292888
|
Status epilepticus
|
744
|
4212 |
SOD1
|
|
decreases_quantity of
|
SYP
|
in skeletal muscle of transgenic mice
|
4214 |
SOD1-p.G37R
|
|
decreases_quantity of
|
SYP
|
in skeletal muscle of transgenic mice
|
|
20223753
|
Amyotrophic lateral sclerosis
|
1,028
|
6437 |
DCTN1-p.G59S
|
|
increases_quantity of
|
SYP
|
at neuromuscular junctions of gastrocnemius muscle
|
|
18094236
|
Amyotrophic lateral sclerosis
|
1,273
|
8666 |
reelin deficiency
|
|
affects_expression of
|
SYP
|
|
|
20417248
|
Schizophrenia
|
2,117
|
17324 |
high-fat diet
|
NOT |
affects_quantity of
|
SYP
|
|
|
18926603
|
Alzheimer disease
|
3,114
|
28621 |
SOD1
|
|
affects_quantity of
|
SYP
|
|
|
22072713
|
Alzheimer disease
|
3,269
|
30119 |
Atp7B mutant mouse
|
|
increases_quantity of
|
SYP
|
in hippocampus
|
|
21517843
|
Wilson disease
|
3,972
|
40381 |
prenatal growth retardation
|
NOT |
affects_quantity of
|
SYP
|
in brain; at 15-17 months of age
|
40382 |
postnatal nutrient restriction with growth restiction
|
NOT |
affects_quantity of
|
SYP
|
in brain; at 15-17 months of age
|
40383 |
postnatal nutrient restriction with growth restiction after prenatal growth retardation
|
NOT |
affects_quantity of
|
SYP
|
in brain; at 15-17 months of age
|
|
23228723
|
Diabetes mellitus, type II
Insulin resistance
|
6,539
|
62808 |
Alzheimer disease
|
|
decreases_expression of
|
SYP
|
in hippocampus neurons; relative to the levels in non-AD brains, most significantly in the hippocampus
|
|
23595620
|
Alzheimer disease
Metabolic
|
6,898
|
67960 |
Metformin
|
|
decreases_expression of
|
SYP
|
|
|
26858121
|
Diabetes mellitus, type II
Insulin resistance
|
8,644
|
89368 |
Trimethylamine N-oxide
|
|
decreases_quantity of
|
SYP
|
in hippocampus; by downregulation of TOR signaling
|
89376 |
SYP
|
|
affects_activity of
|
regulation of synaptic plasticity
|
in hippocampus
|
|
29749694
|
Metabolic
|
9,098
|
109531 |
Phyto-beta-SERM
|
|
increases_expression of
|
SYP
|
in ApoE2 and ApoE3 female mouse brains, but not in ApoE4 animals
|
109544 |
Phyto-beta-SERM
|
NOT |
affects_expression of
|
SYP
|
in ApoE4 female mouse brain
|
|
28934977
|
Neurological
Alzheimer disease
Metabolic
|
9,274
|
98880 |
gut microbiota
|
|
increases_quantity of
|
SYP
|
|
|
26598580
|
Neurological
Gastrointestinal
Metabolic
Major depressive disorder
|
11,851
|
117026 |
SEPTIN3
|
|
interacts (colocalizes) with
|
SYP
|
|
|
15485489
|
Neurodegenerative disorder
|
12,926
|
123846 |
APOE (isoform E4)
|
|
decreases_expression of
|
SYP
|
in ApoE4 mice
|
|
31808750
|
Alzheimer disease
|
13,852
|
130238 |
SYP
|
|
is_expressed_in
|
renal glomerulus
|
|
|
16585060
|
Chronic kidney disease
|