Search Results for "STAT3" - 199 interactions found in 104 entries.

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Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
906
5472 SIRT1 affects_acetylation of STAT3 if SIRT1 is knocked down in liver and adipose tissue of diabetic rats
5475 SIRT1 affects_phosphorylation of STAT3 if SIRT1 is knocked down in liver and adipose tissue of diabetic rats
19549853 Diabetes mellitus, type II
Insulin resistance
1,042
6527 PTPN1 increases_phosphorylation of STAT3 in hypothalamus; if PTPN1 is knocked out in neuronsvia leptin signaling,
6528 LEP increases_phosphorylation of STAT3 in hypothalamus; if PTPN1 is knocked out in neurons
16845389 Diabetes mellitus, type II
Insulin resistance
1,162
7701 IKBKB increases_expression of STAT3 in liver; in LIKK mice
7702 IKBKB increases_phosphorylation of STAT3 in liver; in LIKK mice
7707 IKBKB increases_expression of STAT3 in muscle; in LIKK mice
13331 IL6 affects_expression of STAT3 in muscle; in LIKK mice
15685173 Diabetes mellitus, type II
Insulin resistance
1,189
7928 IL6 increases_phosphorylation of STAT3 in skeletal muscle; at Tyr residues of STAT3
15047622 Diabetes mellitus, type II
Insulin resistance
1,439
10133 IL18 increases_phosphorylation of STAT3
10134 IL18 increases_activity of STAT3
16732281 Diabetes mellitus, type II
Obesity
Insulin resistance
1,453
10255 SPP1 affects_phosphorylation of STAT3 in liver; in obese mice
20107108 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
1,467
10443 MTOR increases_activity of STAT3 in liver
10444 MTOR increases_phosphorylation of STAT3 in liver; at Ser727 of STAT3
10445 STAT3 decreases_activity of insulin receptor signaling pathway in liver
17993646 Diabetes mellitus, type II
Insulin resistance
1,592
11537 inflammatory response increases_expression of STAT3
11562 Epigallocatechin 3-gallate decreases_expression of STAT3
11575 Curcumin decreases_expression of STAT3
11581 Ellagic acid decreases_expression of STAT3 in inflamed cells
11597 Genistein decreases_expression of STAT3 in inflamed cells
11638 STAT3 affects_activity of mRNA transcription
20816778 Diabetes mellitus, type II
Insulin resistance
1,625
11900 STAT3 affects_activity of Obesity
11901 STAT3 affects_activity of Diabetes mellitus, type II
11902 STAT3 affects_activity of infertility
11903 STAT3 affects_quantity of liver
11907 STAT3 affects_activity of decreased energy expenditure
11909 STAT3 affects_quantity of LEP
11910 STAT3 affects_activity of leptin-mediated signaling pathway
11912 STAT3 affects_activity of decreased energy expenditure
11913 STAT3 affects_activity of energy homeostasis
11916 STAT3 affects_activity of reproduction
15070774 Diabetes mellitus, type II
Insulin resistance
1,634
11968 STAT3 affects_activity of Obesity on normal chow diet
12020 STAT3 affects_expression of POMC on normal chow diet
12021 STAT3 affects_activity of Insulin resistance on normal chow diet
12022 STAT3 affects_activity of leptin resistance on normal chow diet
12023 STAT3 affects_activity of polyphagia on normal chow diet
12024 STAT3 affects_expression of SOCS3
12030 STAT3 increases_expression of POMC in POMC neurons
12032 high-fat diet increases_activity of STAT3 in POMC neurons
12033 STAT3 increases_activity of leptin resistance in POMC neurons
12034 STAT3 increases_activity of Insulin resistance in POMC neurons
19759305 Diabetes mellitus, type II
Obesity
Insulin resistance
1,656
12143 Insulin receptor affects_phosphorylation of STAT3 in liver; if IR is incativated in peripheral tissues only
18451994 Diabetes mellitus, type II
Insulin resistance
1,668
12360 IKBKG affects_phosphorylation of STAT3 after high-fat diet, at Tyr residues of STAT3
18216263 Hepatocellular carcinoma
Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
1,899
14597 high-fat diet decreases_phosphorylation of STAT3 in hypothalamus; at Tyr residues, if induced by leptin
16002529 Diabetes mellitus, type II
Insulin resistance
1,912
14651 Palmitic acid decreases_phosphorylation of STAT3 after leptin induction
19808018 Diabetes mellitus, type II
Obesity
Insulin resistance
1,925
14899 exercise NOT affects_phosphorylation of STAT3 in hypothalamus; in lean animals
14901 overnutrition decreases_phosphorylation of STAT3 in hypothalamus
14903 exercise increases_phosphorylation of STAT3 in hypothalamus; in obese animals
20808781 Diabetes mellitus, type II
Obesity
Insulin resistance
1,948
15042 IL6 increases_phosphorylation of STAT3 in skeletal muscle
19502419 Diabetes mellitus, type II
Insulin resistance
1,953
15131 Humanin derivative increases_activity of STAT3
18813209 Alzheimer disease
2,231
19092 LEP increases_phosphorylation of STAT3
19093 calorie restriction increases_phosphorylation of STAT3
21267512 Diabetes mellitus, type II
Obesity
Insulin resistance
2,240
19155 leptin-mediated signaling pathway increases_phosphorylation of STAT3
21037323 Diabetes mellitus, type II
Obesity
Insulin resistance
3,107
28543 LEP increases_activity of STAT3 in brown adipose tissue, in white adipose tissue
9389752 Diabetes mellitus, type II
Insulin resistance
3,129
28801 LEPR increases_activity of STAT3 in hypothalamus; via phosphorylation and dimerization of STAT3
8782827 Diabetes mellitus, type II
Insulin resistance
3,761
37311 IL10 increases_phosphorylation of STAT3 in human T lymphocyte; IL-10 failed to induce STAT3 in glial cells.
22970774 Alzheimer disease
3,795
37657 STAT3 interacts (colocalizes) with mTORC1 complex
18765678 Diabetes mellitus, type II
Insulin resistance
4,233
43259 Irf4 interacts (colocalizes) with Stat3
43412 Stat3 increases_activity of T-helper 17 cell differentiation expression is reduced in Irf4-/- mice
22983707 Hematological
4,260
43916 LEPRb-phosTyr1138 increases_activity of STAT3
43918 JAK2 increases_activity of STAT3 via Tyr phosphorylation
43922 STAT3 increases_expression of SOCS3
20846876 Diabetes mellitus, type II
Obesity
Insulin resistance
4,729
46844 TXNIP decreases_activity of STAT3 in pancreas, in pancreatic beta cells
23975026 Diabetes mellitus, type II
Insulin resistance
4,833
47715 Insulin increases_phosphorylation of STAT3
47720 LEP increases_phosphorylation of STAT3
15715521 Diabetes mellitus, type II
Insulin resistance
5,082
49926 Metformin increases_activity of STAT3 in hypothalamus; after intracerebroventricular injection, via increased phosphorylated STAT3
22950061 Diabetes mellitus, type II
Insulin resistance
5,430
52986 STAT3 increases_activity of WNT5A
17203201 Metabolic
5,910
55872 STAT3 increases_expression of HAMP
Diabetes mellitus, type II
Insulin resistance
Hemochromatosis, type 1
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