Search Results for "SREBF1" - 123 interactions found in 75 entries.

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Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
258
1058 SREBF1 increases_activity of lipid biosynthetic process in liver; when excess energy by carbohydrates is consumed
1059 SREBF1 increases_expression of ACACB in liver; after fasting-refeeding treatment
1061 SREBF1 increases_expression of FASN in liver; after fasting-refeeding treatment
1062 SREBF1 increases_expression of SCD in liver; after fasting-refeeding treatment
1063 SREBF1 increases_expression of GPAT in liver; after fasting-refeeding treatment
1064 SREBF1 increases_quantity of ACLY in liver; after fasting-refeeding treatment
1066 SREBF1 increases_quantity of ME in liver; after fasting-refeeding treatment
1067 SREBF1 increases_quantity of G6PD in liver; after fasting-refeeding treatment
1072 SREBF1 increases_expression of THRSP in liver; after fasting-refeeding treatment
12333 SREBF1 NOT affects_activity of cholesterol biosynthetic process in liver; when excess energy by carbohydrates is consumed
10585467 Diabetes mellitus, type II
Insulin resistance
274
1113 Polyunsaturated fatty acid decreases_quantity of SREBF1
1116 Cycloheximide NOT decreases_quantity of SREBF1 if SREBF1 decay is polyunsaturated fatty acid-dependent
11124951 Diabetes mellitus, type II
Insulin resistance
316
1252 fasting decreases_quantity of SREBF1 in liver nuclei
1255 feeding after fasting increases_quantity of SREBF1 in liver nuclei
1257 SREBF1 increases_activity of fatty acid biosynthetic process
9600904 Diabetes mellitus, type II
Insulin resistance
318
1259 fasting decreases_quantity of SREBF1 in adipose tissue
1260 feeding after fasting increases_quantity of SREBF1 in adipose tissue
1261 SREBF1 increases_expression of LEP
12340 SREBF1 increases_expression of FASN
9421459 Diabetes mellitus, type II
Insulin resistance
341
1343 Metformin decreases_activity of SREBF1 in liver
10973319 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
346
12346 Metformin decreases_expression of SREBF1 in liver
11602624 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
374
1528 SREBF1 affects_expression of Mitochondrial GPAT
9054427 Diabetes mellitus, type II
Insulin resistance
386
1713 Mitochondrial GPAT NOT affects_expression of SREBF1 in liver; if mitochondrial GPAT is overexpressed in liver
16507761 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
401
1750 GPAM NOT affects_quantity of SREBF1
11546763 Diabetes mellitus, type II
Insulin resistance
459
2042 STK11 affects_expression of SREBF1 in liver
16308421 Diabetes mellitus, type II
Peutz-Jeghers syndrome
Insulin resistance
462
12368 PRKAA2 decreases_expression of SREBF1
15855317 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
664
3676 SREBF1 increases_expression of Mitochondrial GPAT
10940327 Diabetes mellitus, type II
Diabetes mellitus, type I
Insulin resistance
Hypothyroidism
787
4463 LPIN1 decreases_expression of SREBF1 if LPIN1 is overexpressed
16950137 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
824
4896 SREBF1 affects_expression of LPIN1 in nucleus
4960 PPARGC1B increases_activity of SREBF1 in liver
19770177 Diabetes mellitus, type II
Obesity
Insulin resistance
889
5247 PPARGC1B affects_expression of SREBF1 in liver; after high-fructose diet, if PPARGC1B expression is knocked down
19254570 Diabetes mellitus, type II
Insulin resistance
1,592
11563 Epigallocatechin 3-gallate decreases_expression of SREBF1
11641 SREBF1 affects_activity of mRNA transcription
20816778 Diabetes mellitus, type II
Insulin resistance
1,668
12352 IKBKG affects_expression of SREBF1 in liver
18216263 Hepatocellular carcinoma
Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
1,736
13042 SREBF1 interacts (colocalizes) with TCF3
13044 SREBF1 increases_expression of INS
13045 SREBF1 increases_expression of INS by interacting with E47 (TCF3) bound to Beta2 (Neurod1)
16055439 Neurological
2,254
19289 INPPL1 NOT affects_expression of SREBF1 in liver
18039790 Diabetes mellitus, type II
Insulin resistance
2,266
19351 SPP1 affects_expression of SREBF1 in liver
21562757 Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
2,773
25688 GIPR NOT affects_expression of SREBF1 in adrenal cortex
22043004 Diabetes mellitus, type II
Insulin resistance
2,823
26070 SREBF1 increases_expression of HSD17B12
19533843 Endocrine
3,558
33077 Homocysteine increases_activity of SREBF1 SREBF1 pathway
33132 SREBF1 affects_activity of atherosclerotic lesions
33133 SREBF1 affects_activity of Alzheimer disease
16973241 Alzheimer disease
Metabolic
Atherosclerosis
3,576
33590 NR1H4 decreases_expression of SREBF1 in liver; via LXR
21991404 Diabetes mellitus, type II
Cholestasis, progressive familial intrahepatic 2
Insulin resistance
3,794
37613 obese Zucker rat increases_expression of SREBF1 in liver
37618 Thiazolidinedione decreases_expression of SREBF1 in liver; in obese Zucker rats
20959535 Diabetes mellitus, type II
Insulin resistance
3,897
39515 FFAR4 affects_expression of SREBF1
22343897 Diabetes mellitus, type II
Insulin resistance
4,285
43976 Olanzapine decreases_expression of SREBF1
23926289 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
4,351
44469 SREBF1 increases_activity of adipose tissue development
44470 SREBF1 increases_expression of PPARG by interacting with E-box elements in the promoter of PPARG
10409739 Metabolic
4,470
45023 cold exposure increases_expression of SREBF1 in epididymal white adipose tissue but not in inguinal white adipose tissue
45025 SREBF1 increases_expression of PPARGC1A in ME8-Tet cells
45031 fatty acid beta-oxidation increases_activity of SREBF1 in brown adipose tissue
45032 SREBF1 increases_expression of PPARGC1A in brown adipose tissue
19962449 Metabolic
4,841
47766 LEP decreases_expression of SREBF1 in liver; in IRS2-/- mice
47864 IRS2 affects_expression of SREBF1 in liver; in IRS2-/- mice
11546755 Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
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