|
2,081
|
| 16772 |
increased circulating insulin level
|
|
increases_quantity of
|
PLAT
|
in blood; in males and in females with normal glucose tolerance
|
| 16778 |
impaired glucose tolerance
|
|
increases_quantity of
|
PLAT
|
in blood; in males, in females
|
| 16783 |
increased circulating insulin level
|
|
increases_quantity of
|
PLAT
|
in blood; in males and in females with glucose intolerance
|
|
10634338
|
Diabetes mellitus, type II
Insulin resistance
|
|
2,143
|
| 17845 |
SERPINE1
|
|
affects_activity of
|
PLAT
|
|
|
19604604
|
Alzheimer disease
|
|
7,433
|
| 73460 |
endothelial cell
|
|
increases_quantity of
|
PLAT
|
|
|
20536686
|
Cardiovascular disease
|
|
8,011
|
| 79230 |
PLAT
|
|
increases_quantity of
|
Tissue plasminogen activator chain A
|
via proteolytic cleavage of the precursor by plasmin
|
| 79232 |
PLAT
|
|
increases_quantity of
|
Tissue plasminogen activator chain B
|
via proteolytic cleavage of the precursor by plasmin
|
|
2496749
|
Cardiovascular disease
|
|
11,065
|
| 112285 |
neural tube formation
|
|
increases_expression of
|
PLAT
|
in neural tube
|
|
19592578
|
Diarrhea 3, secretory sodium, congenital, syndromic
|
|
12,080
|
| 118651 |
PLAT
|
|
increases_quantity of
|
Plasmin
|
together with PLAU
|
| 118652 |
PLAT
|
|
decreases_quantity of
|
PLG
|
together with PLAU
|
| 118657 |
SERPINE1
|
|
decreases_activity of
|
PLAT
|
|
|
32348783
|
Cardiovascular disease
COVID-19
|
|
12,082
|
| 118695 |
Bradykinin
|
|
increases_activity of
|
PLAT
|
|
| 118706 |
Angiotensin II type 1 receptor blocker
|
NOT |
affects_expression of
|
PLAT
|
|
|
32348783
|
Cardiovascular disease
COVID-19
|
|
12,092
|
| 118759 |
Angiotensin (1-9)
|
|
decreases_quantity of
|
PLAT
|
in blood plasma; via AGTR1
|
|
23884911
|
Cardiovascular disease
|
|
12,112
|
| 118912 |
Angiotensin II
|
|
increases_quantity of
|
PLAT
|
in extracellular space
|
| 118914 |
Angiotensin (1-7)
|
|
decreases_quantity of
|
PLAT
|
in extracellular space
|
|
12091055
|
Cardiovascular disease
|
|
12,339
|
| 120789 |
Spironolactone
|
|
increases_quantity of
|
PLAT
|
|
|
11836266
|
Cardiovascular disease
|
|
13,337
|
| 125876 |
SARS-CoV-2 infection
|
|
affects_expression of
|
PLAT
|
|
| 125886 |
SARS-CoV-2 infection
|
|
increases_expression of
|
PLAT
|
|
|
|
COVID-19
|
|
13,349
|
| 125967 |
PLAT
|
|
increases_quantity of
|
Plasmin
|
|
| 125972 |
Thrombin
|
|
increases_quantity of
|
PLAT
|
in glomerular cells
|
|
7924884
|
Nephropathy, diabetic
|
|
13,352
|
| 125977 |
hyperglycemia
|
|
increases_quantity of
|
PLAT
|
mesangial cells
|
| 125986 |
Thrombin
|
|
increases_quantity of
|
PLAT
|
mesangial cells
|
|
7924884
|
Nephropathy, diabetic
|
|
13,359
|
| 126007 |
PLAT
|
|
decreases_quantity of
|
PLG
|
|
| 126008 |
PLAT
|
|
increases_quantity of
|
Plasmin
|
|
|
2966802
|
Hematological
|
|
13,365
|
| 126024 |
Angiotensin II
|
|
increases_quantity of
|
PLAT
|
|
|
12021572
|
COVID-19
|
|
13,368
|
| 126027 |
PLAT
|
|
affects_activity of
|
fibrinolysis
|
|
|
31309890
|
Hematological
|
|
13,539
|
| 127698 |
PLAT
|
|
decreases_quantity of
|
PLG
|
|
| 127702 |
PLAT
|
|
increases_quantity of
|
Plasmin
|
|
| 129032 |
PLAT
|
|
increases_activity of
|
Plasminogen
|
via conversion of inactive plasminogen to active plasmin
|
|
28837538
|
Cancer
|
|
13,540
|
| 127701 |
Angiostatin
|
|
decreases_activity of
|
PLAT
|
in bovine aortic endothelial cells (BAEC), murine melanoma cells (B16F10) or human ovariancarcinoma cells (OVCA 429); by binding to tPA (PLAT)
|
|
10229661
|
Cancer
|
|
13,542
|
| 127708 |
Angiostatin
|
|
decreases_activity of
|
PLAT
|
|
|
|
Hematological
|
|
13,545
|
| 127726 |
Angiostatin
|
|
interacts (colocalizes) with
|
PLAT
|
|
|
12453439
|
Cancer
|
|
13,576
|
| 127970 |
Thyroid-stimulating hormone
|
|
increases_quantity of
|
PLAT
|
in thyroid follicular cells
|
|
12065237
|
Metabolic
|
|
13,736
|
| 128979 |
PLAT
|
|
increases_activity of
|
angiogenesis
|
in thoracic aortas
|
|
11557572
|
Cardiovascular
|
|
13,837
|
| 130052 |
PLAT
|
|
increases_activity of
|
HGF
|
in hepatocytes
|
|
8362987
|
Liver disease, chronic
|
|
13,839
|
| 130088 |
response to fluid shear stress
|
|
affects_activity of
|
PLAT
|
|
|
24352503
|
Chronic kidney disease
|
|
15,273
|
| 144342 |
PLAT
|
|
interacts (colocalizes) with
|
LRP1
|
concerning LRP1 of endothelial cells and astrocytes
|
| 144344 |
PLAT
|
|
increases_processing of
|
PLG
|
into plasmin
|
| 144410 |
PLAT
|
|
increases_quantity of
|
Plasmin
|
via activating plasminogen
|
| 144414 |
PLAT
|
|
is_part_of
|
LRP1-PLAT interaction
|
concerning LRP1 of endothelial cells and astrocytes
|
|
|
Alzheimer disease
|
CIDeRplus