|
58
|
| 179 |
IL1B
|
|
increases_transport of
|
NFKB1
|
into nucleus
|
| 181 |
Sulforaphane
|
|
decreases transport of
|
NFKB1
|
into nucleus; in cytokine treated cells
|
|
19071154
|
Diabetes mellitus, type I
|
|
670
|
| 3581 |
Status epilepticus
|
|
increases_expression of
|
NFKB1
|
in lithium-pilocarpine model
|
| 3586 |
Edaravone
|
|
decreases_expression of
|
NFKB1
|
in lithium-pilocarpine model
|
|
19951488
|
Status epilepticus
|
|
1,110
|
| 7116 |
convulsive seizures
|
|
affects_expression of
|
NFKB1
|
|
| 7120 |
NFKB1
|
|
is localized in
|
neuron
|
|
| 7121 |
NFKB1
|
|
is localized in
|
glia
|
|
|
15571975
|
Status epilepticus
Epilepsy, temporal lobe
|
|
1,384
|
| 9548 |
NFKB1
|
|
affects_expression of
|
GRIN1
|
|
|
12679240
|
Schizophrenia
|
|
1,592
|
| 11535 |
inflammatory response
|
|
increases_expression of
|
NFKB1
|
|
| 11636 |
NFKB1
|
|
affects_activity of
|
mRNA transcription
|
|
|
20816778
|
Diabetes mellitus, type II
Insulin resistance
|
|
1,820
|
| 13662 |
NFKB1
|
|
increases_expression of
|
IRAK2
|
|
| 13680 |
NFKB1
|
|
affects_activity of
|
mir-146a
|
|
| 13681 |
mir-146a
|
|
affects_activity of
|
NFKB1
|
|
|
20937840
|
Alzheimer disease
|
|
1,933
|
| 14867 |
convulsive seizures
|
|
increases_transport of
|
NFKB1
|
|
|
20155797
|
Status epilepticus
Epilepsy, temporal lobe
|
|
2,110
|
| 17240 |
Autism
|
|
increases_expression of
|
NFKB1
|
|
| 17246 |
Autism
|
|
affects_activity of
|
NFKB1
|
|
|
21573053
|
Autism
|
|
2,724
|
| 25351 |
MAVS
|
|
increases_expression of
|
NFKB1
|
|
|
16125763
|
Immunological
Postpartum depression
|
|
2,727
|
| 25356 |
NFKB1
|
|
increases_expression of
|
UBE2M
|
after Sendai virus infection
|
| 25357 |
NFKB1
|
|
increases_expression of
|
CCL5
|
after Sendai virus infection
|
|
21896491
|
Immunological
|
|
2,736
|
| 25379 |
ESR1
|
|
affects_expression of
|
NFKB1
|
|
|
15514030
|
Endocrine
|
|
3,409
|
| 31671 |
IKBKB
|
|
increases_phosphorylation of
|
NFKB1
|
|
|
10469655
|
Endocrine
|
|
3,410
|
| 31672 |
NR3C1
|
|
interacts (colocalizes) with
|
NFKB1
|
|
|
8290595
|
Endocrine
|
|
3,411
|
| 31673 |
RELA
|
|
interacts (colocalizes) with
|
NFKB1
|
|
| 31674 |
NFKB1
|
|
is_part_of
|
NF-kappaB complex
|
|
|
14743216
|
Endocrine
|
|
3,555
|
| 33022 |
Anatabine
|
|
decreases_activity of
|
NFKB1
|
|
| 33025 |
NFKB1
|
|
affects_expression of
|
BACE1
|
|
|
21958873
|
Alzheimer disease
|
|
3,591
|
| 33622 |
UBE2M
|
|
decreases_quantity of
|
NFKB1
|
|
|
11953428
|
Postpartum depression
|
|
3,749
|
| 36465 |
Pioglitazone
|
|
decreases_expression of
|
NFKB1
|
in kidney
|
|
18388116
|
Diabetes mellitus, type II
Insulin resistance
Nephropathy, diabetic
|
|
3,929
|
| 39885 |
Naringenin
|
|
decreases_activity of
|
NFKB1
|
in kidney; in diabetic mice
|
|
22117528
|
Diabetes mellitus, type II
Insulin resistance
Nephropathy, diabetic
|
|
4,179
|
| 43008 |
Schizophrenia
|
|
decreases_expression of
|
NFKB1
|
in superior temporal gyrus
|
| 43009 |
Schizophrenia
|
|
decreases_quantity of
|
NFKB1
|
in superior temporal gyrus
|
| 43010 |
Schizophrenia
|
|
decreases_activity of
|
NFKB1
|
in superior temporal gyrus
|
|
23132271
|
Schizophrenia
|
|
4,201
|
| 43122 |
Diabetes mellitus, type II
|
|
increases_expression of
|
NFKB1
|
in blood
|
|
23337395
|
Diabetes mellitus, type II
Insulin resistance
|
|
4,593
|
| 45703 |
15-Deoxy-delta-12,14-PGJ2
|
|
decreases_activity of
|
NFKB1
|
by directly inhibiting NF-kappaB (p50) activation at the IP-10 promoter
|
| 45705 |
PPARG
|
|
decreases_activity of
|
NFKB1
|
|
|
10843708
|
Cardiovascular disease
Atherosclerosis
|
|
5,252
|
| 51210 |
Breast cancer
|
|
increases_expression of
|
NFKB1
|
|
|
19995559
|
Breast cancer
Diabetes mellitus, type II
Insulin resistance
|
|
6,196
|
| 57946 |
NFKB1
|
|
is_part_of
|
NFKB1-NCOR1-TAB2 complex
|
|
| 57951 |
MAP3K1
|
|
increases_activity of
|
NFKB1
|
via translocation of NCOR1-TAB2-HDAC3 complex
|
| 57952 |
NCOR1-TAB2-HDAC3 complex
|
|
decreases_activity of
|
NFKB1
|
|
| 57953 |
NFKB1
|
|
increases_expression of
|
CD82
|
|
| 57956 |
AICD-APBB1-KAT5 complex
|
|
increases_activity of
|
NFKB1
|
via displacement of NCOR1-TAB2-HDAC3 complex
|
| 57957 |
AICD-APBB1-KAT5 complex
|
|
increases_expression of
|
CD82
|
via displacement of NCOR1-TAB2-HDAC3 complex
|
|
12150997
|
Diabetes mellitus, type II
Insulin resistance
|
|
6,205
|
| 58204 |
mTORC1 complex
|
|
increases_transport of
|
NFKB1
|
to the nucleus; where NFKB1 binds to the intragenic sequences of the HDAC2 gene.
|
| 58223 |
MTOR
|
|
affects_activity of
|
NFKB1
|
if MTOR is activated, by modulating NF-kappaBp50 transcriptional activity.
|
| 58374 |
NFKB1
|
|
interacts (colocalizes) with
|
HDAC2
|
with intragenic sequences of the HDAC2 gene.
|
| 58375 |
NFKB1
|
|
increases_expression of
|
HDAC2
|
via binding to the intragenic sequences of the HDAC2 gene.
|
|
24448241
|
Hepatocellular carcinoma
Cancer
|
|
6,264
|
| 58964 |
Gamma-secretase inhibitor GSI-XXI
|
|
increases_expression of
|
NFKB1
|
in Jurkat cells
|
|
20332460
|
Cancer
Leukemia
|
|
6,387
|
| 61647 |
SIRT1
|
|
affects_activity of
|
NFKB1
|
|
|
25955819
|
Metabolic
|
|
6,481
|
| 62591 |
Saturated fatty acid
|
|
increases_expression of
|
NFKB1
|
via stimulated microglia
|
|
25998028
|
Alzheimer disease
|
|
6,819
|
| 66321 |
NOD2
|
|
increases_expression of
|
NFKB1
|
in B lymphocytes
|
| 66324 |
NFKB1
|
|
is_part_of
|
NF-kappaB complex
|
|
|
23709157
|
Inflammatory bowel disease 1
Inflammatory bowel disease
|
|
6,890
|
| 67284 |
Nephropathy, diabetic
|
|
increases_expression of
|
NFKB1
|
in kidney
|
| 67288 |
LiCl
|
|
decreases_expression of
|
NFKB1
|
in kidney
|
|
27284338
|
Diabetes mellitus, type II
Insulin resistance
Nephropathy, diabetic
|
|
6,893
|
| 67321 |
LiCl
|
|
decreases_activity of
|
NFKB1
|
in liver
|
|
23051669
|
Diabetes mellitus, type II
Insulin resistance
|
CIDeRplus