Search Results for "MLXIPL" - 40 interactions found in 21 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
368
1502 HSPA5 affects_quantity of MLXIPL in liver
19363290 Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
369
1487 Thapsigargin increases_quantity of MLXIPL in nucleus, in liver; in the presence of a high glucose concentration
19363290 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
459
2046 STK11 NOT affects_expression of MLXIPL in liver
16308421 Diabetes mellitus, type II
Peutz-Jeghers syndrome
Insulin resistance
462
12369 PRKAA2 decreases_expression of MLXIPL
15855317 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
732
4092 Glucose increases_activity of MLXIPL
4093 cAMP decreases_activity of MLXIPL
4094 Glucose 6-phosphate increases_activity of MLXIPL
4095 Glucose 6-phosphate increases_transport of MLXIPL into the nucleus
4096 MLXIPL increases_expression of ACAC in response to glucose
4097 MLXIPL increases_expression of FASN in response to glucose
4098 MLXIPL increases_expression of PKLR in response to glucose
4123 Linoleic acid decreases_activity of MLXIPL
38987 Eicosapentaenoic acid decreases_activity of MLXIPL
38988 Docosahexaenoic acid decreases_activity of MLXIPL
16614395 Diabetes mellitus, type II
Insulin resistance
824
4935 MLXIPL increases_activity of lipid biosynthetic process in liver; independent of SREBF1c
19770177 Diabetes mellitus, type II
Obesity
Insulin resistance
3,622
34293 Triiodothyronine increases_expression of MLXIPL in liver, in adipose tissue
21941681 Diabetes mellitus, type II
Insulin resistance
Hypothyroidism
Hyperthyroidism
4,019
41431 MLXIPL rs17145738 affects_expression of MLXIPL in subcutaneous adipose tissue
20686565 Diabetes mellitus, type II
Coronary artery disease
Insulin resistance
4,780
47316 MLXIPL increases_expression of TXNIP in pancreas, in pancreatic beta cells
47319 EP300 interacts (colocalizes) with MLXIPL in pancreas, in pancreatic beta cells
47321 MLXIPL increases_activity of histone H4 acetylation in pancreas, in pancreatic beta cells
19411249 Diabetes mellitus, type II
Insulin resistance
4,842
47862 LEP decreases_expression of MLXIPL in adipose tissue; after intracerebroventricular leptin infusion
17823267 Diabetes mellitus, type II
Insulin resistance
6,456
61259 AMPK decreases_activity of MLXIPL via phosphorylation
22117616 Diabetes mellitus, type II
Cancer
Insulin resistance
6,511
61915 Diabetes mellitus, type II increases_expression of MLXIPL in liver
18842111 Diabetes mellitus, type II
Insulin resistance
7,526
76041 NR1H4 decreases_activity of MLXIPL if FXR is activated;
76090 Glucose increases_transport of MLXIPL the nuclear translocation of ChREBP is initiated;
76091 MLXIPL decreases_quantity of Glucose when the nuclear translocation of ChREBP is initiated by high levels of glucose, via promoting the conversion of glucose into fatty acids;
76092 MLXIPL increases_quantity of Fatty acid when the nuclear translocation of ChREBP is initiated by high levels of glucose, via promoting the conversion of glucose into fatty acids;
76093 NR1H4 interacts (colocalizes) with MLXIPL
76094 MLXIPL increases_activity of hepatic steatosis in mice
76095 NR1H increases_expression of MLXIPL
76105 MLXIPL increases_expression of PKLR PKLR catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis.
25073467 Gastrointestinal
Metabolic
8,202
82669 Betaine decreases_quantity of MLXIPL in liver
82670 high-sucrose diet increases_quantity of MLXIPL in liver
17702954 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
8,394
86085 Fructose increases_activity of MLXIPL
28714900 Fatty liver disease, nonalcoholic
8,567
88246 insulin secretion increases_expression of MLXIPL
29057834 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
8,661
89989 Urate increases_activity of MLXIPL
24065788 Diabetes mellitus, type II
Insulin resistance
8,995
94352 Metformin decreases_activity of MLXIPL via decreasing the high-glucose-stimulated nuclear entry rate, as well as their recruitment on the TXNIP promoter
26147751 Metabolic
13,547
127764 Nephropathy, diabetic decreases_expression of MLXIPL in kidney
24371263 Nephropathy, diabetic
14,030
132547 HNF1A rs886039544 decreases_expression of MLXIPL
30507613 MODY, type III
16,332
157375 MLXIPL increases_expression of SREBF1c in adipose tissue
Diabetes mellitus, type II
Obesity
Insulin resistance
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