1,976
|
15485 |
MAS1
|
|
affects_activity of
|
ACE2
|
|
|
20660625
|
Diabetes mellitus, type II
Insulin resistance
|
2,002
|
15889 |
A-779
|
|
decreases_activity of
|
MAS1
|
|
|
20808802
|
Diabetes mellitus, type II
Insulin resistance
|
6,741
|
65314 |
DLG4
|
|
increases_activity of
|
MAS1
|
|
65315 |
DLG4
|
|
interacts (colocalizes) with
|
MAS1
|
|
|
23701246
|
Diabetes mellitus, type II
Coronary artery disease
Insulin resistance
|
11,717
|
116374 |
Angiotensin (1-7)
|
|
affects_activity of
|
MAS1
|
|
|
30404071
|
Diabetes mellitus, type II
Insulin resistance
|
11,748
|
116373 |
Angiotensin (1-7)
|
|
increases_activity of
|
MAS1
|
|
|
32333398
|
COVID-19
|
11,776
|
116592 |
Angiotensin (1-7)
|
|
increases_activity of
|
MAS1
|
|
116595 |
MAS1
|
|
increases_activity of
|
arachidonic acid secretion
|
|
116597 |
MAS1
|
|
increases_phosphorylation of
|
AKT1
|
|
116615 |
MAS1
|
|
affects_activity of
|
cardiac fibrosis
|
|
116616 |
MAS1
|
|
decreases_activity of
|
heart failure
|
|
116617 |
MAS1
|
|
affects_activity of
|
abnormal circulating lipid level
|
|
116619 |
MAS1
|
|
affects_activity of
|
impaired glucose tolerance
|
|
116620 |
MAS1
|
|
affects_activity of
|
Insulin resistance
|
|
116621 |
MAS1
|
|
affects_activity of
|
increased circulating insulin level
|
|
116622 |
MAS1
|
|
affects_activity of
|
glucose import
|
in white adipose tissue
|
|
23463883
|
Diabetes mellitus, type II
Insulin resistance
Cardiovascular disease
|
11,777
|
116631 |
embryo development
|
|
affects_expression of
|
MAS1
|
|
|
26029927
|
Diabetes mellitus, type II
Insulin resistance
|
11,821
|
116759 |
Angiotensin (1-7)
|
|
increases_activity of
|
MAS1
|
|
116760 |
MAS1
|
|
decreases_activity of
|
AGTR1
|
|
|
32341442
|
COVID-19
|
11,918
|
117242 |
Angiotensin (1-5)
|
|
increases_activity of
|
MAS1
|
in atrium
|
|
27660028
|
Cardiovascular disease
|
11,922
|
117257 |
Angiotensin (1-7)
|
|
increases_activity of
|
MAS1
|
in LPS plus IFNG-stimulated macrophages
|
117275 |
MAS1
|
|
decreases_expression of
|
IL1B
|
in LPS plus IFNG-stimulated macrophages
|
117276 |
MAS1
|
|
decreases_expression of
|
CCL2
|
in LPS plus IFNG-stimulated macrophages
|
117277 |
MAS1
|
|
decreases_expression of
|
TNF
|
in LPS plus IFNG-stimulated macrophages
|
117282 |
MAS1
|
|
decreases_activity of
|
inflammatory response
|
in LPS plus IFNG-stimulated macrophages
|
|
30918468
|
Lung disease
|
11,928
|
117302 |
Angiotensin (1-7)
|
|
increases_activity of
|
MAS1
|
in HEK293 cells
|
|
27217404
|
Cardiovascular disease
|
11,934
|
117316 |
MAS1
|
|
interacts (colocalizes) with
|
AGTR1
|
|
117329 |
MAS1
|
|
decreases_activity of
|
AGTR1
|
|
117330 |
Angiotensin II
|
NOT |
increases_activity of
|
MAS1
|
|
117331 |
MAS1
|
|
affects_activity of
|
inositol phosphate biosynthetic process
|
|
117332 |
MAS1
|
|
affects_activity of
|
calcium ion homeostasis
|
|
117333 |
MAS1
|
|
is_part_of
|
AGTR1-MAS1 complex
|
in HEK293 cells
|
|
15809376
|
Cardiovascular disease
|
11,935
|
117317 |
Angiotensin (1-7)
|
NOT |
interacts (colocalizes) with
|
MAS1
|
|
|
29928987
|
Cardiovascular disease
|
11,936
|
117318 |
Angiotensin (1-7)
|
|
increases_activity of
|
MAS1
|
in kidney
|
117361 |
MAS1
|
|
increases_activity of
|
vasodilation
|
in aorta
|
|
12829792
|
Cardiovascular disease
|
11,937
|
117319 |
MAS1
|
|
interacts (colocalizes) with
|
AGTR2
|
|
117362 |
MAS1
|
|
is_part_of
|
AGTR2-MAS1 complex
|
in astrocytes
|
|
28461604
|
Cardiovascular disease
|
12,017
|
117744 |
Angiotensin (1-9)
|
NOT |
increases_activity of
|
MAS1
|
|
|
29962859
|
Cardiovascular disease
|
12,029
|
118020 |
Angiotensin (1-7)
|
|
increases_activity of
|
MAS1
|
|
118023 |
Angiotensin (1-7)
|
NOT |
increases_activity of
|
MAS1
|
in mammary arteries, in splanchnic vessel, in aorta
|
118024 |
Neuropeptide FF
|
|
increases_activity of
|
MAS1
|
|
118025 |
Alamandine
|
|
increases_activity of
|
MAS1
|
|
118026 |
Angiotensin III
|
|
increases_activity of
|
MAS1
|
|
118027 |
Angiotensin IV
|
|
increases_activity of
|
MAS1
|
|
118028 |
Angioprotectin
|
|
increases_activity of
|
MAS1
|
|
118049 |
MAS1
|
|
increases_activity of
|
insulin receptor signaling pathway
|
|
|
30934934
|
Diabetes mellitus, type II
Insulin resistance
Cardiovascular disease
|
12,034
|
118072 |
MAS1
|
|
interacts (colocalizes) with
|
AGTR1
|
in alveolar epithelial
cells, in alveolar macrophages
|
|
22009550
|
Lung disease
|
12,056
|
118271 |
Angiotensin (1-7)
|
|
interacts (colocalizes) with
|
MAS1
|
|
118314 |
Angiotensin (1-7)
|
|
increases_activity of
|
MAS1
|
|
118318 |
MAS1
|
|
decreases_activity of
|
AGTR1
|
|
|
19065996
|
Diabetes mellitus, type II
Insulin resistance
|
12,064
|
118372 |
MAS1
|
|
is_expressed_in
|
endothelium
|
|
118419 |
MAS1
|
|
affects_activity of
|
abnormal circulating lipid level
|
|
118420 |
MAS1
|
|
affects_activity of
|
increased circulating insulin level
|
|
118421 |
MAS1
|
|
affects_activity of
|
abnormal circulating leptin level
|
|
118422 |
MAS1
|
|
affects_activity of
|
increased abdominal adipose tissue amount
|
|
118423 |
MAS1
|
|
affects_activity of
|
impaired glucose tolerance
|
|
118424 |
MAS1
|
|
affects_activity of
|
decreased insulin sensitivity
|
|
118425 |
MAS1
|
|
affects_activity of
|
glucose import
|
into adipocytes; if stimulated by insulin
|
118426 |
MAS1
|
|
affects_quantity of
|
SLC2A4
|
in adipocytes
|
|
19065996
|
Diabetes mellitus, type II
Insulin resistance
|
12,082
|
118672 |
Angiotensin (1-7)
|
|
increases_activity of
|
MAS1
|
|
118673 |
MAS1
|
|
decreases_activity of
|
inflammatory response
|
|
118674 |
MAS1
|
|
decreases_activity of
|
response to oxidative stress
|
|
118675 |
MAS1
|
|
increases_activity of
|
vasodilation
|
|
|
32348783
|
Cardiovascular disease
COVID-19
|
12,098
|
118800 |
MAS1
|
|
is_expressed_in
|
blood platelet
|
|
118802 |
Angiotensin (1-7)
|
|
interacts (colocalizes) with
|
MAS1
|
in blood platelets
|
|
18026570
|
Cardiovascular disease
|
12,099
|
118801 |
Angiotensin (1-7)
|
|
interacts (colocalizes) with
|
MAS1
|
in blood platelets
|
118805 |
MAS1
|
|
increases_quantity of
|
NO
|
in blood platelets
|
119560 |
MAS1
|
|
decreases_activity of
|
thrombosis
|
|
|
18026570
|
Cardiovascular disease
|
12,183
|
119485 |
MAS1
|
|
decreases_activity of
|
fibrosis
|
in lung
|
119500 |
MAS1
|
|
decreases_activity of
|
cardiac interstitial fibrosis
|
|
119510 |
MAS1
|
|
decreases_activity of
|
response to oxidative stress
|
in pulmonary artery, in lung
|
|
20581171
|
Lung disease
|
12,330
|
120871 |
Angiotensin (1-7)
|
|
increases_activity of
|
MAS1
|
|
120872 |
MAS1
|
|
decreases_activity of
|
Insulin resistance
|
|
|
23893738
|
Diabetes mellitus, type II
Insulin resistance
|
12,337
|
120769 |
Aldosterone
|
|
decreases_expression of
|
MAS1
|
|
120775 |
Spironolactone
|
|
decreases_quantity of
|
MAS1
|
|
|
31165585
|
Chronic kidney disease
|
12,362
|
121130 |
MAS1
|
|
increases_activity of
|
Phosphatidylinositol 3-kinase
|
in adipocytes
|
121157 |
MAS1
|
|
increases_activity of
|
glucose import
|
|
121209 |
MAS1
|
|
affects_activity of
|
glucose homeostasis
|
|
121210 |
MAS1
|
|
affects_activity of
|
lipid homeostasis
|
|
121211 |
MAS1
|
|
affects_activity of
|
increased circulating insulin level
|
|
121212 |
MAS1
|
|
affects_quantity of
|
LEP
|
|
121213 |
MAS1
|
|
affects_quantity of
|
abdominal adipose tissue
|
|
121214 |
MAS1
|
|
affects_expression of
|
SLC2A4
|
in adipose tissue
|
121215 |
MAS1
|
|
affects_expression of
|
PPARG
|
in adipose tissue
|
|
24450744
|
Diabetes mellitus, type II
Insulin resistance
|
13,516
|
127465 |
MAS1
|
|
decreases_activity of
|
ERBB2
|
in aortic smooth muscle cells
|
|
26536590
|
Diabetes mellitus, type II
Insulin resistance
|
13,667
|
128386 |
GHR
|
|
affects_quantity of
|
MAS1
|
in heart, in kidney
|
|
22947377
|
Cardiovascular disease
|
13,891
|
131222 |
Dopamine
|
|
increases_expression of
|
MAS1
|
in kidney
|
|
21701066
|
Renal
|